Monosaccharides

(1S) -1- [(2S, 3S,4R) -4-Hydroxymethyl-3- hydroxy- N-methyl-1- azetidinyl] -1, 2- ethanediol is a synthetic sugar that can be used as a glycosylation or methylation agent. It is a white powder with a molecular weight of 342. The purity of this product is > 98%. This product has CAS No. 517862-65-8.

Raloxifene-4'-D-glucuronide D4 lithium salt is a synthetic glycosylate drug, which belongs to the group of anti-estrogens. Raloxifene-4'-D-glucuronide D4 lithium salt is used for the treatment of postmenopausal osteoporosis and prevention of osteoporotic fractures in women with intact uterus. It has been shown to inhibit bone resorption, increase bone mineral density and reduce the incidence of vertebral fractures in postmenopausal women. Raloxifene-4'-D-glucuronide D4 lithium salt can be synthesized using a click chemistry reaction which involves the addition of an azide to an alkyne followed by copper catalysis and subsequent reduction with sodium borohydride. Synthesis of this compound can be achieved without any purification steps due to its high purity.

Methyl α-D- glucopyranoside is a methylated sugar used as an inhibitor of lectin-conjugate binding. Methyl α-D- glucopyranoside is commonly used in protein purification for eluting glycoproteins and other glycoconjugates from affinity chromatography columns of agarose lectin. Methyl α-D- glucopyranoside is also known as Methyl alpha-D-glucoside or alpha-Methyl-glucoside.

5-O-tert-Butyldimethylsilyl-2,3-O-isopropylidene-L-ribono-1,4-lactone is a high purity custom synthesis and custom synthesis of complex carbohydrates. 5-O-tert-Butyldimethylsilyl-2,3-O-isopropylidene-L-ribono--1,4--lactone is a fluorination and an oligosaccharide that contains methylated sugar. It is a polysaccharide with a click modification that can be used for glycosylation and methylation. This product has been shown to be effective in the synthesis of oligosaccharides.

GDP-D-mannose is a natural mannosyl donor and substrate for mannosyltransferases that catalyses mannosylation, for instance during the synthesis of the trimannoside core of complex, high-mannose or hybrid N-glycans. GDP-D-mannose is widely used in (chemo)enzymatic synthesis of oligosaccharides and its biosynthesis occurs from glucose-6-phosphate over several steps. GDP-D-mannose consists of a D-mannose unit, α-glycosydically linked to the nucleotide guanosine diphosphate (GDP). Examples of this important reaction would be the transfer of mannosyl moieties onto the dolichol-P-P-GlcNAc2 precursor of N-glycans in the endoplasmatic reticulum, with release of GDP, or the mannosylation reactions during GPI-anchor (bio)synthesis. GDP-D-mannose has also been used for the in vitro synthesis of b-mannan oligosaccharides.

4-Methoxyphenyl 2,4,6-tri-O-benzoyl-a-D-mannopyranoside is a glycosylation product of mannose with 4-methoxybenzoic acid. It is a complex carbohydrate that has been modified by methylation and click modification. The fluorination increases the reactivity of the hydroxyl groups on the sugar ring. This product can be synthesized in high purity and custom synthesis.

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6'-O-Acetylpaniculoside II is an oligosaccharide that contains a methylated saccharide. It has CAS No. 836-50-4 and Click modification, which is a chemical reaction between the glycone of a saccharide and an electrophile. 6'-O-Acetylpaniculoside II is also a glycosylation product of a polysaccharide and it can be custom synthesized to produce high purity carbohydrates. This compound is fluorinated for complex carbohydrate chemistry.

Deoxygalactonojirimycin acetonide is a custom-synthesized, complex carbohydrate that belongs to the group of Oligosaccharides. It is a modified saccharide with methylation and glycosylation. Deoxygalactonojirimycin acetonide is an active ingredient that has been synthesized for use in cancer research. This compound is a high-purity, fluorinated sugar with Click modification that can be used to study the structure-activity relationships of carbohydrate-based drugs.

N-Acetyl D-mannosamine (ManNAc) is an aldohexose (2-acetamido-2-deoxymannose) in which the axial hydroxyl group at position 2 is replaced by a N-acetyl group (Collins, 2006). It has been reported that N-acetyl D-mannosamine supplementation, may provide novel means to break the link between obesity and hypertension (Peng, 2019). N-Acetyl-D-mannosamine and N-acetyl-D-glucosamine are the essential precursors of sialic acid, the specific monomer of polysialic acid, a bacterial pathogenic determinant, for example, Escherichia coli K1 uses both amino sugars as carbon sources. It has been reported that ManNAc can be used as a treatment for hereditary inclusion body myopathy, an adult-onset, progressive neuromuscular disorder and also for renal disorders involving proteinuria and hematuria due to podocytopathy and/or segmental splitting of the glomerular basement membrane (Galeano, 2007).

2,3:5,6-Di-O-isopropylidene-D-talose is a custom synthesis of methylated oligosaccharides. It is a complex carbohydrate that contains both a monosaccharide and a polysaccharide. 2,3:5,6-Di-O-isopropylidene-D-talose is a modification of the sugar D(+)-talose (a pentasaccharide), which has been fluorinated to make it more stable. This product has high purity, and can be used in many different applications such as click chemistry, oligosaccharide synthesis, or fluorination reactions.
2,3:5,6-Di-O-isopropylidene-D-talose is an Oligosaccharide that is a Polysaccharide. It can be used as an inhibitor for DNA polymerase α and β enzymes in PCR reactions

L-Fucose is a monosaccharide that is an important component of glycoproteins and glycolipids. L-Fucose is also found in the cell wall of bacteria. The most abundant sources of L-fucose are from the hydrolysis of lactose or sucrose by bacteria, or as a result of intestinal microbial fermentation. L-Fucose has been shown to be involved in the regulation of many metabolic processes, including the glomerular filtration rate and sephadex g-100 binding capacity in the kidney. It has also been shown to improve growth in infant rats with protein malnutrition. The enzyme that catalyzes the conversion of D-arabinose to L-fucose is known as fucokinase.

2,3-O-Isopropylidene-5-O-tosyl-D-ribonic acid-1,4-lactone is a synthetic 2,3:5,6-diisopropylidene glycoside of D-ribose. It is a methylated sugar with an alpha-(2,3)-linked D-(+)-glucopyranosyl moiety and an alpha-(2,5)-linked L(+)-fucopyranosyl moiety. This compound can be used as a building block for the synthesis of polysaccharides and glycoconjugates. 2,3:5,6-Diisopropylidene glycoside of D-ribose is also used to synthesize oligosaccharides in carbohydrate chemistry.

Methyl 2,3-di-O-acetyl-4,6-O-(4-methoxybenzylidene)-a-D-glucopyranoside is a synthetic saccharide that has been modified with methylation and fluorination. It is an oligosaccharide derived from glucose that can be obtained through the custom synthesis of a polysaccharide. This product has CAS No. 52526-77-9 and is available in high purity. It can be used for the modification of monosaccharides or other carbohydrates.

L-g-Ethylidene glutamic acid is an organic compound that is used in the production of pharmaceuticals, agrochemicals, and other chemicals. It can be synthesized by the methylation of L-glutamic acid with formaldehyde and sodium cyanoborohydride. L-g-Ethylidene glutamic acid has also been modified by a click reaction to create a fluorinated derivative. This product is a white crystalline solid that has a CAS number. The product is available at high purity and can be ordered as either monosaccharide or polysaccharide.
L-g-Ethylidene glutamic acid is a sugar that belongs to the carbohydrate family and can be classified as complex carbohydrates because it comprises two or more sugars linked together. This product may also be referred to as an oligosaccharide or polysaccharide, depending on its molecular size.

D-Glucuronolactone is supposed to be involved in detoxification processes.

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This complex carbohydrate is a modification of the 6-O-tert.butyl dimethylsilyl]psicofuranose. It is an Oligosaccharide that has been modified with methylation, glycosylation, and Click modification of the sugar moieties. The CAS number for this complex carbohydrate is 10963-29-3, and it has a purity of 99%.

2,4,6-Tri-O-benzyl-3-O-benzyl-D-mannopyranose is a modification of the monosaccharide D-mannopyranose. It is a carbohydrate that can be custom synthesized and has high purity with a CAS number. The 2,4,6-tri-O-benzoyl group can be used for glycosylation reactions to produce polysaccharides. This modification also has the ability to be fluorinated or methylated by using the corresponding reagents.
2,4,6-Tri-O-benzoyl-3-O-benzyl mannopyranose is an oligosaccharide that can serve as a building block for more complicated carbohydrates like polysaccharides. It has not been shown to have any toxicity in animals and is used as a food additive in some countries.

6-Deoxy-L-allitol is a white crystalline solid that melts at 122°C. It has an amorphous character and may be present as a mixture of rotations, form, and crystalline polymorphs. 6-Deoxy-L-allitol can be oxidized to its diol derivative by hydrogen peroxide or sodium periodate. This compound is soluble in water, methanol, and acetone. The molecular weight of this compound is 179.06 g/mol.

Reference compound for metabolites of the pentosephosphate pathway

Ribulose 5-phosphate sodium is a chemical that can be used to inhibit the enzyme ribulose phosphate reductase. Ribulose 5-phosphate sodium has been shown to inhibit glycolaldehyde production in the chloroplasts of plants, effectively reducing the amount of carbon dioxide produced. This chemical has also been shown to have an inhibitory effect on other enzymes involved in carbon fixation and assimilation. The effectiveness of this chemical is dependent on the specific plant species and environmental conditions.

D-glucose 6-phosphate is an intermediate in the hexose monophosphate shunt pathway. It is formed by the enzyme phosphoglucomutase from D-glucose 1-phosphate and UTP. D-glucose 6-phosphate is also an important intermediate in glycolysis. The conversion of D-glucose 6-phosphate to glucose 1,6-bisphosphate occurs through a series of reactions catalyzed by enzymes that are sensitive to inhibition by magnesium ions. These reactions include the phosphofructokinase, hexokinase, and pyruvate kinase reactions. The accumulation of glucose 6-phosphate leads to increased levels of lactate production and decreased levels of ATP production. This may be due to its ability to inhibit monoamine reuptake, which would lead to decreased synthesis of dopamine and serotonin.

D-Arabino-5-hexulosonic acid is an intermediate in the pentose phosphate pathway. It is a component of the hexuronate, which is an important precursor for galactitol, 6-phosphate, and acid dehydrogenase. D-Arabino-5-hexulosonic acid is also an important intermediate in the glycolytic pathway for ATP production. The gene product has been shown to be involved in aerobic glycolysis, which is utilized by Staphylococcus aureus to produce energy from glucose fermentation. D-Arabino-5-hexulosonic acid plays a role in ion exchange and mitochondrial metabolism as well.

Methyl D-arabinofuranoside is an antimycobacterial agent that inhibits the synthesis of mycolic acids, which are important components of the cell wall of Mycobacterium tuberculosis. Methyl D-arabinofuranoside has been shown to be active against drug-resistant strains and has been well tolerated by animals. This compound can be synthesized from 2,4-dichlorophenylacetic acid and arabinose in two steps. The first step involves a three-component condensation reaction with sodium hydroxide, hydrochloric acid, and 2,4-dichlorophenylacetic acid. The second step is a nucleophilic attack on the pyran ring of methyl D-arabinofuranoside with hypophosphorous acid. Methyl D-arabinofuranoside can also be prepared by reacting sodium nitrosobenzene with sodium benzene sulfinate in alcoholic solution

4-Deoxy-D-glucose is a sugar that is synthesized by the condensation of two molecules of erythrose. It has been shown to be an efficient donor substrate for nucleophilic attack, which can lead to the synthesis of glycosides and other natural products. 4-Deoxy-D-glucose is also a competitive inhibitor of uridine diphosphate (UDP) glucose, which is an enzyme involved in the biosynthesis of UDP sugars and glycoproteins. The concentration of 4-deoxy-D-glucose affects its catalytic mechanism, as it acts as a competitive inhibitor at high concentrations. Molecular modeling has revealed that this molecule adopts a chair conformation with significant solvent exposure.

3'-a-Sialyl-N-acetyllactosamine sodium salt is a high purity, custom synthesis sugar. It has been modified with fluorination, glycosylation, and methylation to provide the desired properties. This product is also available in other forms such as monosaccharide and saccharide. 3'-a-Sialyl-N-acetyllactosamine sodium salt can be used in various applications including Click modification, fluoroamination, glycosylation, carbonylation and methylation. CAS No. 350697-53-9

D-Xylulose 5-phosphate sodium salt is a synthetic monosaccharide that can be used in the synthesis of oligosaccharides, polysaccharides, and complex carbohydrates. It is also used in glycosylation reactions. D-Xylulose 5-phosphate sodium salt has been fluorinated to provide better stability and solubility. The compound has a molecular weight of 206.06 g/mol and a CAS number of 105931-44-0. This product is available for custom synthesis upon request.

2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-a-D-galactopyranose is a fluorinated complex carbohydrate that has been modified by methylation and acetylation. This product is a custom synthesis that has not been previously described in the scientific literature. It is synthesized from 2, 3, 4, 6 tetraacetyl alpha D galactopyranoside and 2 deoxy alpha D galactopyranose. The chemical properties of this compound are similar to those of other complex carbohydrates such as glycogen and heparin.

D-Glucose 6-phosphate, disodium salt is an antibiotic that is used to treat gram-negative bacterial infections. It binds to the bacterial ribosome and inhibits protein synthesis, which leads to cell death by inhibiting the production of proteins vital for cell division. This drug has been shown to be active against a wide range of bacteria, including resistant strains such as Escherichia coli and Salmonella typhimurium. D-Glucose 6-phosphate, disodium salt also has anti-inflammatory properties and can be used as an anti-bacterial agent in the treatment of typhoid fever.

Glucose pentaacetate is a form of glucose that reacts with boron trifluoride etherate to produce anomers. This process can be used to synthesize the anomeric form of glucose, which is important for the biosynthesis of glycosides. Glucose pentaacetate has been shown to react with nitrate and trifluoride, forming conjugates with aluminum and chloride. The catalytic stereocontrol of this reaction allows for the production of disaccharides without hydrogen chloride or formylation.

D-ribulose-5-phosphate sodium is a nucleotide sugar that is one of the ribonucleotides, which are fundamental components of RNA. D-ribulose 5-phosphate sodium has been shown to be an intermediate in the metabolism of ribulose and catalyzes the oxidation of d-arabinose. This enzyme also catalyses the synthesis of fatty acids and participates in reactions involving glycerolipids and phospholipids. The reaction mechanism involves a double displacement with simultaneous attack by a water molecule on C2' and C3'. When deuterium is present, it affects the rate of these reactions in a way that depends on the orientation of the substrate to the enzyme.

Decyl D-glucopyranoside is a sodium salt of decyl D-glucopyranoside that is used as a detergent additive in cleaning compositions. Decyl D-glucopyranoside has shown antimicrobial activity against both Gram-positive and Gram-negative bacteria, including methicillin resistant Staphylococcus aureus (MRSA) and Clostridium perfringens. Decyl D-glucopyranoside has also been shown to have chemical stability at high temperatures, making it useful in the manufacture of lacrimal gland preparations and cationic surfactants.

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Benzyl 2,3-O-isopropylidene-a-D-mannofuranoside is a fluorinated monosaccharide that is synthesized using glycosylation and polysaccharide modification. This product has a CAS number of 20689-03-6 and can be used for complex carbohydrate synthesis. It has been shown to have high purity.

ADP-L-glycero-b-D-manno-heptose is a synthetic, fluorinated oligosaccharide that is custom synthesized and modified. It has a high purity level and CAS No., as well as being a complex carbohydrate that can be modified with methylation or click modification to generate desired properties. ADP-L-glycero-b-D-manno-heptose is an Oligosaccharide with a glycosylation and methylation. This compound can be used in the synthesis of saccharides, polysaccharides, or other complex carbohydrates.