APIs for research and impurities

<p>Moexipril diketopiperazine is a drug product that is custom synthesized in a high purity and analytical grade. It is metabolized through metabolism studies and has been shown to have natural, synthetic, impurity and research and development standards. Moexipril diketopiperazine has CAS No. 103733-51-3. It has been shown to be a metabolite of Moexipril hydrochloride, which is an angiotensin II receptor antagonist used to treat hypertension and congestive heart failure. This product is also used as a standard for HPLC analysis.</p>

<p>Please enquire for more information about Moexipril-d5 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5α,6α-Epoxycholestanol-d7 is an impurity of a cholestatic drug product. It can be used as a research and development standard or as an impurity standard in the production of drugs. 5α,6α-Epoxycholestanol-d7 has been characterized by GC/MS and HPLC techniques. This compound is also useful for pharmacopoeia purposes, drug development, and metabolic studies.</p>

<p>Brexpiprazole impurity 10 is a drug product that is used as an analytical reference standard for the quality control of brexpiprazole. This drug product is a synthetic substance with a high purity and is designed for use in HPLC analyses. This impurity can be used as a reference to identify other metabolites of brexpiprazole, such as 3-desacetyl-brexpiprazole, which are not necessarily identified by mass spectrometry. The CAS number for Brexpiprazole impurity 10 is 15116-41-3 and it has been assigned the IUPAC name 2-[2-[(2S)-2-[[(3S)-3-[4-(1,1-dimethylethyl)phenoxy]propyl]amino]-3-methylbutanoyl]-1H-indol-5-yl]acetic acid.</p>

<p>[1-Hydroxy-3-(methylisopentylamino)propylidene] bisphosphonic acid monosodium (ibandronic acid impurity) is a metabolite of ibandronate, which is used in the treatment of osteoporosis. It is an impurity found in ibandronate drug products and can be detected using HPLC.</p>

<p>Please enquire for more information about Cefazolinamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Atorvastatin is a potent inhibitor of the enzyme HMG-CoA reductase, which is responsible for the conversion of HMG-CoA to mevalonate. This inhibition reduces the production of cholesterol and other lipids in the liver. Metabolism studies have shown that atorvastatin undergoes extensive presystemic metabolism by cytochrome P450 enzymes, primarily CYP3A4 and CYP2C9. The drug is converted to inactive metabolites that are eliminated primarily through renal excretion. Atorvastatin has not been found to inhibit any of the following: cytochrome P450 1A1/2, 2C8/9, 2D6, 2E1, 3A4/5 or glucuronidases.</p>

<p>3alpha-Hydroxy pravastatin sodium salt is a white to off-white crystalline powder. It is used as an analytical standard for 3alpha-hydroxypravastatin and its metabolites. The CAS number is 81093-43-8, and the molecular weight of this compound is 467.6 g/mol. This product can be custom synthesized to meet your needs.</p>

<p>Quinovin is a Chinese medicinal compound that has been shown to have potent anticancer properties. It works by inhibiting kinases, which are enzymes that play a crucial role in the growth and proliferation of cancer cells. Quinovin has been found to induce apoptosis, or programmed cell death, in various types of cancer cells. This compound is an analog of other kinase inhibitors that have been developed for the treatment of cancer in humans. Quinovin has also been found to inhibit the growth of tumors in animal models and to be excreted in urine after administration. Overall, Quinovin represents a promising candidate for the development of new anticancer therapies.</p>

<p>N-Desmethyl azithromycin B is a metabolite of the macrolide antibiotic azithromycin. It is an impurity in the drug product, and is present as an analytical standard for HPLC. N-Desmethyl azithromycin B can be found in the urine of patients taking azithromycin, but at much lower concentrations than the parent drug. This impurity is not toxicologically relevant, but may interfere with some analytical methods.</p>

<p>2,8-Diazabicyclo[4.3.0]nonane is a research and development (R&amp;D) impurity standard with a purity of ≥98%. This product has CAS number 169533-56-6 and is classified as a synthetic drug product. 2,8-Diazabicyclo[4.3.0]nonane can be used for the synthesis of drugs and pharmaceuticals, as well as for the study of metabolic pathways in vitro and in vivo. It is also an analytical standard for HPLC analysis, which can be used to measure the concentration of metabolites in urine or blood samples. 2,8-Diazabicyclo[4.3.0]nonane has been shown to inhibit the metabolism of a variety of compounds that are metabolized by cytochrome P450 enzymes such as CYP1A2 and CYP2C9, which are important enzymes involved in drug metabolism processes.</p>

<p>Please enquire for more information about Ethyl 2-cyano-4-methylpent-2-enoate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2,3-Dichloro-6-(2,4-dichlorophenoxy)phenol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Nileprost is a medicinal inhibitor of protein kinases that has shown promising results in the treatment of cancer. It works by inducing apoptosis in cancer cells, effectively stopping their growth and proliferation. Nileprost has been extracted from human urine and is an analog of a Chinese anticancer compound. This inhibitor is effective against a wide range of kinases, making it a potent tool for cancer treatment. Nileprost has shown particular promise in inhibiting tumor growth in human studies. Its ability to selectively target cancer cells while leaving healthy cells intact makes it an attractive option for the development of new cancer therapies.</p>

<p>Bucumolol is a medicinal compound that has shown promise as an anticancer agent. It works by inhibiting the activity of certain proteins in cancer cells, leading to apoptosis (cell death) and disrupting the cell cycle. Bucumolol is an analog of a natural product found in human urine and Chinese medicinal herbs. It has been shown to be effective against various types of tumors, including breast, colon, and lung cancers. Bucumolol functions as a kinase inhibitor, blocking enzymes that are involved in cancer cell growth and proliferation. Its potent anticancer properties make it a promising candidate for further research into cancer treatments.</p>

<p>Please enquire for more information about N-Boc-4-nitro-L-phenylalanine t-butyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>Tymazoline hydrochloride is a medicine that belongs to the class of imidazolines. It is used to treat allergic diseases and other conditions where it is desirable to reduce the production of histamines. Tymazoline hydrochloride has been shown to inhibit histamine release from mast cells in vitro, and it is also used as an antihistamine. Tymazoline hydrochloride crystallizes from water as the dihydrate, and its diffraction patterns have been determined using synchrotron radiation. The molecule has an orthorhombic crystal structure with spacings of 0.7-0.8 nm between planes and intensities of 5-6 cm-1 in the X-ray region. Techniques such as molecular modelling and crystallography have been used to study this drug's structure and properties.</p>

<p>N-Boc-(R)-2-(3-thiazolidinylcarbonyl)pyrrolidine is a molecule that is used to develop analytical methods. It is a key intermediate in the synthesis of metformin hydrochloride, an anti-diabetic drug. N-Boc-(R)-2-(3-thiazolidinylcarbonyl)pyrrolidine can be used as a surrogate for impurities in pharmaceuticals and other substances. This product can be used to validate analytical methods and has been shown to have high sensitivity. <br>N-Boc-(R)-2-(3-thiazolidinylcarbonyl)pyrrolidine can be synthesized by reacting acetonitrile with melamine, which is an impurity found in products such as milk powder, baby formula, and wheat gluten. The compound is then purified using RP-HPLC.</p>

<p>Desmethyl dabrafenib is a synthetic drug product that is used in research and development. It is an impurity standard for dabrafenib, a prodrug of dabrafenib which has been shown to inhibit the growth of cancer cells by inhibiting the synthesis of proteins. Desmethyl dabrafenib is metabolized through CYP3A4/5-mediated oxidation and glucuronidation. It also undergoes phase I metabolism through CYP1A2 and 2C19, leading to formation of a major metabolite with no activity. This compound has been shown to have natural sources in plants such as rhubarb and soybeans.</p>

<p>Please enquire for more information about N-(4-Hydroxyphenyl)acetamide sulfate-d3 sodium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>L-Mevalonic acid lithium salt is an analog of mevalonic acid, a key intermediate in the biosynthesis of cholesterol and other important biomolecules. This compound has been shown to inhibit kinases involved in cancer cell growth and proliferation, making it a potential anticancer agent. L-Mevalonic acid lithium salt has been found to induce apoptosis (programmed cell death) in human cancer cells and inhibit the activity of cyclin-dependent kinases, which are involved in regulating the cell cycle. It is also a potent inhibitor of protein prenylation, which is essential for tumor cell survival. This compound can be detected in urine and has been used as a biomarker for various cancers, including breast and prostate cancer. Overall, L-Mevalonic acid lithium salt shows great promise as a potential therapeutic agent for cancer treatment.</p>

<p>This product is an organic compound that has a molecular formula of C6H7N3O2. It is a white solid with a melting point of 76.5 °C and an elution time of 7 minutes (range, 1-10 minutes). The detection method is based on the color change from yellow to blue in the presence of dimethylformamide (DMF). This product is used as a solvent for various chemical reactions and can be used in the synthesis of other products. 3-(Formylamino)-1H-pyrazole-4-carboxamide is used in analytical chemistry to determine substances such as pH, ionic strength, and concentration. In addition, this product can be used to quantify substances such as drugs or pharmaceuticals.</p>

<p>Pyridine-2-methanol methiodide is a drug product that is used as an HPLC standard. It is also used in the development of new drugs, natural products, and research and development. Pyridine-2-methanol methiodide has been shown to have anti-inflammatory properties in metabolism studies. This compound has a niche application as an API impurity standard for analytical purposes. The CAS number for this compound is 3313-51-7. Synthetic methods are required to produce this substance. It is a high purity chemical with pharmacopoeia applications.</p>

<p>O-Desmethyl mycophenolate mofetil (ODMM) is a metabolite of mycophenolic acid, a drug that is used to treat immunosuppressive diseases. ODMM can be synthesized in the laboratory and used as an analytical standard for mycophenolic acid and its metabolites. ODMM is also a metabolic product of mycophenolate mofetil, which has been shown to have anti-inflammatory properties.</p>

<p>Please enquire for more information about 7-Desmethyl-9-(5-oxohexyl) pentoxifylline including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1,3-Benzodioxol-5-yl[4-(2-chloroethoxy)phenyl]methanone (1,3-BDE) is a synthetic compound that is intended for use as an analytical reference standard. 1,3-BDE has been shown to inhibit the growth of Mycobacterium tuberculosis and Mycobacterium avium complex in vitro. This drug product is intended for research and development purposes only.</p>

<p>Mercaptopurine impurity standard is a drug product that is used as an analytical reference standard in the development of drugs. Mercaptopurine impurity standard is a natural metabolite of 6-mercaptopurine, which is used to treat leukemia and other forms of cancer. It has been shown to have an anti-inflammatory effect, but this has not been confirmed. Mercaptopurine impurity standard is a synthetic compound that is made synthetically for use as an impurity standard. It has also been shown to be metabolized by cytochrome P450 enzymes, glutathione reductase, or conjugation with glucuronic acid. Mercaptopurine impurity standard has been shown to be stable under acidic conditions and heat treatment at temperatures up to 200°C.</p>

<p>3,4-Dihydroxyphenylacetic acid-d5 is a drug product that is used as an impurity standard for HPLC. It has been shown to be a metabolite of 3,4-dihydroxyphenylacetic acid and may be found in the urine of patients taking drugs containing this compound. The stability of 3,4-dihydroxyphenylacetic acid-d5 in biological matrices has been determined by incubation studies with rat liver homogenates. This product is also used as an analytical reagent for the detection of other metabolites or impurities in drugs.</p>

<p>N-Demethyl pazopanib is a synthetic drug that has been researched and developed for the treatment of cancer. It is an impurity standard, custom synthesis, and drug product. Synthetic N-demethyl pazopanib is used in clinical trials as a research and development tool to explore the metabolism of this drug and its metabolites. High purity N-demethyl pazopanib is used as a pharmacopoeia reference material for HPLC analysis in pharmacological studies. The metabolite of N-demethyl pazopanib has been found to be carcinogenic in animal studies. Metabolism studies have shown that N-demethyl pazopanib undergoes extensive hydroxylation and glucuronidation, which are detoxification pathways for xenobiotics in mammals.</p>

<p>2-(4-(3-(2-(Trifluoromethyl)-10H-phenothiazin-10-yl)piperazin-1-yl)ethyl undecanoate is an analytical standard used as a reference compound in the drug development process. It is also used as a pharmacopoeia standard and a custom synthesis. 2-(4-(3-(2-(Trifluoromethyl)-10H-phenothiazin-10-yl)piperazin-1-yl)ethyl undecanoate is synthesized from natural or synthetic sources. This product has been shown to have an impurity level of less than 1%. 2-(4-(3-(2-(Trifluoromethyl)-10H-phenothiazin-10-yl)piperazin-1-yl)ethyl undecanoate is not known to be metabolized by the human body and does not produce any metabolites.</p>

<p>Fluticasone Furoate Impurity L is an impurity of Fluticasone Furoate, a drug product. It has been used as a HPLC standard and as a pharmaceutical reference material for the pharmacopoeia. This impurity can also be used in research and development for drug metabolism studies. The purity of Fluticasone Furoate Impurity L is high and it is natural with no synthetic activity.</p>

<p>Impentamine dihydrobromide (IMB) is a research and development drug product that has been synthesized for the treatment of epilepsy. IMB is an impurity standard for impentamine, a synthetic drug that inhibits the enzyme acetylcholinesterase and has been shown to be effective in the treatment of Alzheimer's disease. Impentamine dihydrobromide is a metabolite of impentamine, which inhibits the enzyme acetylcholinesterase and has been shown to be effective in the treatment of Alzheimer's disease. Impentamine dihydrobromide binds to acetylcholinesterase by competitive inhibition and causes an accumulation of acetylcholine in the synaptic cleft. This accumulation leads to increased neurotransmission at nerve terminals, because acetylcholine is necessary for neurotransmitter release.</p>

<p>2-Hydroxy-2,3-tetrahydrofuranyl entecavir is a drug product that is an impurity standard for 2-hydroxy-2,3-dihydrofuranilide. It is used as a synthetic intermediate in the manufacture of entecavir, which is an antiviral agent used to treat hepatitis B virus infection. 2H2TFE has been shown to be metabolized by CYP450 enzymes and may have niche therapeutic uses. It also has a high purity level and can be used as a analytical reference material or API impurity. CAS No. 1984788-96-6</p>

<p>Bupropion is a racemic mixture of two enantiomers. The (R)-isomer is the more active form and is used for the treatment of major depressive disorder, seasonal affective disorder, and nicotine addiction. Bupropion has been shown to inhibit monoamine oxidase type A in humans and other mammals. This inhibition may be responsible for its antidepressant effects. The drug also has an effect on the liver, which can lead to serious side effects such as seizures or death if not monitored carefully. Bupropion has a high affinity for α1-acid glycoprotein, which plays a role in drug interactions with other drugs that are metabolized by this protein.</p>

<p>N-Methyl-N-(3-chloropropyl)homoveratrylamine is a chlorinated alkylating agent that has been shown to accumulate in the myocardium. It is an anaesthetic that can be recycled and used as a nutrient. N-Methyl-N-(3-chloropropyl)homoveratrylamine binds to DNA, which blocks the synthesis of RNA and protein. This drug has been demonstrated to have antiarrhythmic effects, but it is not effective against cardiac arrhythmias caused by digitalis or hypoxia. N-Methyl-N-(3-chloropropyl)homoveratrylamine also has an antagonist effect on the central nervous system and may be useful for treating convulsions.</p>

<p>This product is a synthetic impurity of Allopurinol. It is a cyclization reaction product of dimethylhydrazine and allopurinol in the presence of an organic solvent such as DMF.</p>

<p>N-(3-Trifluoromethylphenyl)-phenylamine is a research and development drug product that is used as an analytical impurity standard. It has a CAS number of 101-23-5 and is classified under the trade name 3TFPPA. The chemical formula for N-(3-Trifluoromethylphenyl)-phenylamine is C12H8F3NO. This compound can be synthesized from phenylamine, 3-trifluoromethylaniline, and hydrochloric acid. The molecular weight of this compound is 197.19 g/mol, which falls within the range of 195 to 200 g/mol. N-(3-Trifluoromethylphenyl)-phenylamine can be found in the following pharmacopoeia: USP (United States Pharmacopeia), EP (European Pharmacopoeia), JP (Japanese Pharmacopeia), BP</p>

<p>Metabolite of benserazide</p>

<p>KSI-3716 is a potent inhibitor of kinases, which are enzymes that play a critical role in cancer cell growth and survival. This inhibitor has been shown to be effective against Chinese and human kinases, making it a promising candidate for the treatment of various types of cancer. KSI-3716 is an analog of oseltamivir, a drug used to treat influenza. It has been found to induce apoptosis in tumor cells by inhibiting the activity of protein kinases. KSI-3716 also shows anticancer activity in vivo, as demonstrated by its ability to inhibit tumor growth in mice models. This inhibitor may have potential therapeutic applications for the treatment of cancer and other diseases related to kinase dysregulation.</p>

<p>O-De(3-fluorobenzyl) lapatinib ditosylate (OFLB) is a drug product that is supplied as a white to light yellow crystalline powder. It has been custom synthesized for the purpose of drug development and research. OFLB is an analytical standard and metabolite, which will be used in metabolism studies. This product is not intended for use in humans or animals.</p>

<p>Please enquire for more information about Clobetasol Propionate - Impurity D including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about L-Trans-1-methyl-4-propyl-2-pyrrolidinecarboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Hydrochlorothiazide is a sulfonamide that inhibits the activity of the enzyme, angiotensin-converting enzyme (ACE), which is responsible for converting angiotensin I to the potent vasoconstrictor, angiotensin II. It also has antihypertensive effects by blocking the production of aldosterone, which causes sodium retention and leads to high blood pressure. It is a byproduct in reactions with substances such as valsartan. Hydrochlorothiazide may react chemically with other medicines such as ampicillin and cefaclor.</p>

<p>Naftifine-d3 is an analytical standard for HPLC. It is a drug product that is used to determine the purity of active pharmaceutical ingredients and drug products. Naftifine-d3 is also an impurity standard for the pharmacopoeia, which can be used to develop assays for testing drugs for purity. This compound is a metabolite of naftifine hydrochloride, which belongs to the group of topical antibiotics. Naftifine-d3 has been found in natural sources such as plants and fungi. It can also be synthesized or obtained from various types of raw materials, including plant extracts and coal tar derivatives.</p>

<p>8-Benzyloxy-5-[(R)-2-bromo-1-(tertbutyldimethylsilyloxy)ethyl]-1H-quinolinone is a drug product that is used as an analytical standard in metabolism studies. It has been shown to be a natural impurity in the API, and is found in the synthesis of a custom synthesis. 8-Benzyloxy-5-[(R)-2-bromo-1-(tertbutyldimethylsilyloxy)ethyl]-1H-quinolinone has been synthesized and characterized as an impurity standard for HPLC analysis. This substance has been used extensively in drug development and research as well as being a pharmacopoeia grade material.</p>

<p>Sitagliptin Hydrazine Diamide impurity is an analytical reference material that has been manufactured in accordance with the requirements of the United States Pharmacopeia (USP) and the European Pharmacopoeia (EP). The material is a white to off-white crystalline powder. It has a purity of 99.9% with a specific gravity of 1.06 g/cm3 and a melting point of 176-177°C. This material is an impurity standard for Sitagliptin Hydrazine Diamide, CAS No. 2072867-07-1, which is used as an anti-diabetic drug product in niche markets.</p>

<p>Cereulide is a potent inhibitor of apoptosis and has been shown to have medicinal properties in Chinese traditional medicine. It is a protein kinase inhibitor that has been found to be effective against various types of cancer cells, including human tumor cell lines. Cereulide analogs have been developed as potential anticancer agents due to their ability to inhibit kinases involved in cancer progression. This compound has also been detected in urine samples from patients with acute gastroenteritis caused by Bacillus cereus, indicating its potential as a diagnostic marker for this condition. With its promising medicinal properties, Cereulide continues to be studied for its potential therapeutic applications.</p>

<p>Scopine-2,2-dithienyl glycolate is a catalyst that belongs to the class of dithienyl glycolates. Scopine-2,2-dithienyl glycolate is used in the pharmaceutical industry as an average catalyst for reactions and can be used to recover dimethylbenzene. The method of detection for scopine-2,2-dithienyl glycolate is based on its ability to absorb light at a wavelength of 360 nm. The reaction solution must be monitored carefully during the synthetic process because it has been shown that it can react with water or air and form hydrogen sulfide gas. If this happens, the reaction solution will become cloudy or turbid. This product is a white crystalline solid that appears as tiny needles and has a melting point of 173 degrees Celsius (340 degrees Fahrenheit).</p>

<p>Methylprednisolone 21-propionate is a drug product that is used in the treatment of inflammation and autoimmune diseases. It has been used in research and development to develop a natural, synthetic, and analytical standard for the drug product. Methylprednisolone 21-propionate is metabolized by glucuronidation or sulfation. The impurity standards are used to identify any potential impurities or metabolites that may be present in the API. This drug product is also an analytical standard that can be used as a reference material for pharmacopoeia testing.</p>

<p>Lysine-methotrexate is a monoclonal antibody that binds to the DNA template of Leishmania. This protein can be used for the diagnosis of leishmaniasis and other diseases caused by this parasite. The binding of lysine-methotrexate to the DNA template blocks transcription, preventing RNA from being synthesized from DNA. Lysine-methotrexate also has chemotactic activity and cytostatic effects. It may be useful in treating inflammatory diseases and depression, as well as cancer. Lysine-methotrexate is an immunosuppressant and can be used in polyclonal antibodies or monoclonal antibodies to produce an antigen against which the immune system can react.</p>

<p>Linagliptin impurity E is a metabolite of the drug Linagliptin. It is an analytical reference material that is used to calibrate HPLC and GC-MS methods for quality control and purity assessment of Linagliptin. This impurity standard is also used for metabolism studies.</p>

<p>Methyl 4-methyl-3-[2-(propylamino)acetamido]thiophene-2-carboxylate is an impurity that can be found in the drug product. It is a metabolite of clozapine, which is used to treat schizophrenia and other psychiatric disorders. This impurity can be detected by HPLC or LC/MS analysis and quantified using a calibration curve generated from standards. Methyl 4-methyl-3-[2-(propylamino)acetamido]thiophene-2-carboxylate may also be found in the urine as an indicator of clozapine use.</p>

<p>Please enquire for more information about Levofloxacin impurity 19 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone is a research and development impurity standard for synthesis. It is a synthetic, high purity compound with a CAS number of 89991-52-6. The chemical is not found in nature and does not have any natural metabolites. Des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone has been shown to be metabolized by the liver into various metabolites that have been identified through analysis of urine samples. The metabolite of des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone may be used as an analytical standard for HPLC methods.</p>

<p>9,13β-Dehydro epinastine is a synthetic impurity that is an analytical reference material. It is a metabolite of the drug epinastine and has been shown to have pharmacological activity.</p>

<p>Moexipril methyl ester analog hydrochloride is a drug product that has been custom synthesized for research and development. It is a high purity, analytical grade compound with CAS No. 1356841-17-2. Moexipril methyl ester analog hydrochloride is metabolized through metabolic studies and is a natural metabolite of the drug moexipril. This substance can be found in the pharmacopoeia and is used as an impurity standard. Moexipril methyl ester analog hydrochloride also has niche applications in synthetic chemistry research and development.</p>

<p>2-Deschloro aripiprazole is a drug that belongs to the class of antipsychotics. It is an atypical antipsychotic with a high affinity for human albumin and α1-acid glycoprotein, which are plasma proteins. 2-Deschloro aripiprazole has been shown to interact with human albumin and α1-acid glycoprotein in vitro, and it has been suggested that this interaction may be responsible for its pharmacological effects. 2-Deschloro aripiprazole has also been shown to bind to the dopamine D2 receptor, which is thought to be responsible for its therapeutic effects as an antipsychotic. The molecular interactions between 2-deschloro aripiprazole and human albumin have been studied using isothermal titration calorimetry (ITC) and molecular docking studies. These studies have helped us understand how 2-deschloro aripiprazole binds to human album</p>

<p>Betanidine or betanidine is a glycosidic dye or pigment responsible to provide their color to the plant. It belongs to the family of betalain and is used as coloring agent in the food industry. Betadinine is also involved in the in the metabolism of betalains via tyrosinase regulation. It has high antioxidant properties and in certains studies in mice it has been proved to be involved in the regulation of blood glucose levels.</p>

<p>Aurantinidin chloride is a molecule that has been shown to inhibit the growth of prostate cancer cells in vitro. It also inhibits fatty acid synthesis and induces apoptosis in prostate cancer cells. Aurantinidin chloride can be used as a dietary supplement to prevent or treat cancer. It is fat-soluble and can be absorbed by skin, which makes it useful for skin conditions. Aurantinidin chloride has been shown to inhibit the transfer mechanism for the uptake of fatty acids from the intestines into the bloodstream, which may provide therapeutic benefits in pediatric patients with malabsorption syndromes. Aurantinidin chloride also has an anti-inflammatory effect due to its ability to inhibit prostaglandins.</p>

<p>Salmeterol ep impurity A is an API impurity in the drug product 1-(RS)-1-[4-hydroxy-3-(hydroxymethylphenyl]-2-[(4-phenylbutyl)aminoethanol. It is a synthetic, natural, and pharmacopoeia impurity standard. The CAS number for this compound is 1798014-51-3. Salmeterol ep impurity A has a molecular weight of 255.9 g/mol and chemical formula of C24H30ClNO5.</p>

<p>Fluocortolone Impurity 8 is a drug product. It is an impurity standard for fluocortolone and has been purified from natural sources. Fluocortolone Impurity 8 is a metabolite of fluocortolone and has been synthesized for research purposes. Fluocortolone Impurity 8 is also a drug product that has been developed by the Pharmaceutical Research and Development team at the company with CAS No. 87-69-2. Fluocortolone Impurity 8 can be used as an analytical standard, API impurity, or pharmacopoeia reference material in metabolic studies.</p>

<p>9-Demethyl FR-901235 is a synthetic compound that is used as an impurity standard for the synthesis of drugs. It is not intended to have any pharmacological activity, and the only known metabolic pathway is through hydrolysis in the liver by esterases. 9-Demethyl FR-901235 has been shown to be a metabolite of FR-900520, and it has been used in metabolism studies. The substance has been identified as an analytical standard for HPLC analysis.</p>

<p>Please enquire for more information about Dihydro artemisinin tetrahydrofuran acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Chlorhexidine dihydrochloride impurity B is an impurity found in chlorhexidine dihydrochloride, a drug that is used as an antiseptic and disinfectant. It is a metabolite of chlorhexidine and has been detected in urine and plasma samples. This impurity has no known pharmacological activity. The purity of this compound is not less than 99%.</p>

<p>3' - Destrifluoromethyl 2' - trifluoromethyl cinacalcet is a metabolite of cinacalcet, which is a drug used for the treatment of secondary hyperparathyroidism. It is an impurity in the drug product and can be identified by HPLC.</p>

<p>Prothoate is a medicinal analog that acts as an inhibitor of kinases. It has been shown to have anticancer properties and can induce apoptosis in cancer cells. Prothoate has been found to be effective against various types of tumors, including those of the lung and breast. This inhibitor has been isolated from Chinese urine and can target specific proteins involved in tumor growth and progression. Prothoate may offer a promising new approach for the treatment of cancer.</p>

<p>2-Amino-5,6-dichloro-3,4-dihydroquinazoline hydrobromide is a metabolite of the drug product 2-[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)ethylamino]benzeneacetic acid. It has been shown to inhibit protein synthesis in vitro and in vivo.</p>

<p>Please enquire for more information about 2-[(2-Cyclopentylphenoxy)methyl]-oxirane including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cyamemazine sulfoxide is a histamine H1 receptor antagonist. It has been shown to have strong affinity for the serotonin 5-HT2C and dopamine D2 receptors, as well as the atrial 5-HT2A receptors. Cyamemazine sulfoxide has a low oral bioavailability of about 10% and is metabolized in the liver to cyamemazine and its active form, cyamemazine sulfoxide. Cyamemazine sulfoxide binds to serotonin 5-HT2C receptors with a high affinity, which leads to inhibition of serotonin release from nerve endings in the brain. This drug also inhibits dopamine release from nerve endings in the brain and has been shown to have cardiac effects on heart rate and contractility.</p>

<p>Nitromifene citrate is a nonsteroidal drug that inhibits the enzyme fatty acid synthase, thereby preventing the production of prostaglandins. It has been shown to inhibit tumor growth in mice and to be effective against autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Nitromifene citrate also binds to neurokinin-1 receptor and inhibits tissue culture granulosa cells. This drug has been shown to have clinical significance in the treatment of breast cancer. Nitromifene citrate is metabolized by the liver and is taken up into the brain where it can affect brain functions, such as emotional behavior or memory. Nitromifene citrate is synthesized by cultured cells in vitro and has been used for research purposes in vivo.</p>

<p>N-(1-Oxobutyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine (GW1929) is a potent vasodilator that is used for the treatment of hypertension. It is synthesized by condensation of sodium hydroxide with 2-(4′-chlorophenyl)piperazine followed by methyl esterification and chloride acylation. The synthesis of GW1929 has been accomplished in two steps: carbonate cyclization and valsartan hydrolysis. In the first step, the carboxylic acid group of GW1929 was converted to its corresponding chloride compound which was then reacted with methyl bromide to yield the desired product. The second step involved hydrolysis of GW1929 with potassium carbonate, after which it was oxidized with azide to form an ester. Sodium</p>

<p>(R,R)-Solifenacin succinate is a pharmaceutical agent that acts as an antimuscarinic drug. It has been shown to be effective in wastewater treatment, where it was found to reduce the amount of solifenacin and optimised organic chemicals in the water. This drug has also been shown to have antagonist properties against the muscarinic receptor M3.</p>

<p>1,3-Bis(9H-carbazol-4-yloxy)-2-propanol is a metabolite of carvedilol. It is not active as a drug, but may have pharmacological effects. 1,3-Bis(9H-carbazol-4-yloxy)-2-propanol is used as an impurity standard for HPLC analysis of carvedilol in the pharmaceutical industry.</p>

<p>Ciprofibrate-o-β-glucuronide is the major metabolite of ciprofibrate in humans. It can be detected in urine by a variety of analytical methods, including magnetic resonance spectroscopy, voltammetry, and microscopy. Ciprofibrate-o-β-glucuronide is an enantiomer of ciprofibrate and has been shown to have an enzymatic hydrolysis rate of 0.07% per hour. This hydrolysis process is catalyzed by cytochrome P450 enzymes. Ciprofibrate-o-β-glucuronide is also found in pharmaceutical formulations and excreted from the body with a half life of 4 hours.</p>

<p>Prilocaine is a synthetic chemical that is used as an active ingredient in some local anesthetic preparations. It is a metabolite of lidocaine and has been shown to be more potent than lidocaine in animal studies. Prilocaine hydrochloride is the free base form of prilocaine, which is soluble in water and alcohol. This product can be used as a reference standard for quality control purposes or as an analytical impurity standard for the analysis of drug products containing prilocaine.</p>

<p>Desloratadine is a drug that belongs to the group of antihistamines and is indicated for the treatment of allergic rhinitis. It has been shown to be as effective as loratadine, cetirizine, and fexofenadine in clinical trials. Desloratadine is metabolized by cytochrome P450 enzymes including CYP2D6 to its active form, desloratadine N-oxide. The metabolites are excreted in the urine.</p>

<p>DMAC-PDB is an aromatic cleavable linker commonly used in protein and drug conjugation. It enables controlled release of payloads under specific chemical conditions.</p>

<p>Please enquire for more information about 3’,4’-Di-o-methoxy 3,7-bis(benzyloxy) quercetin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2,2-Bis(3-methylthiophen-2-yl)tetrahydrofuran including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Sambacolignoside is a natural compound that has been shown to have bioactivities. Sambacolignoside has been shown to inhibit the growth of cancer cells in vitro, including bladder, prostate and breast cancer cells. This compound is also able to induce apoptosis in these cells. Sambacolignoside can be used as a dietary supplement or as part of a profiling study for bladder cancer.</p>

<p>Methyl 2-(4-biphenylyl)propionate is a custom synthesis that is used for metabolism studies. It is a natural product, although it can be synthesized. Methyl 2-(4-biphenylyl)propionate has been shown to have pharmacopoeia and HPLC standards, as well as impurities and metabolites that can be used for analytical purposes. Methyl 2-(4-biphenylyl)propionate is an impurity standard in the drug development of niche drugs, such as synthetic penicillins and cephalosporins. Methyl 2-(4-biphenylyl)propionate has been used in research and development for its ability to bind to proteins in the adrenal cortex.</p>

<p>Cp-66713 mesylate is a synthetic drug product with a molecular formula of C17H19NO2 and a molecular weight of 269.34. It has the following CAS number: 91896-58-1. The purity of this compound is &gt;99% (HPLC).</p>

<p>2-Acetamido-N-benzyl-3-hydroxypropanamide is an analog of a Chinese kinase inhibitor that has been shown to have anticancer properties. This compound induces apoptosis in human cancer cells by inhibiting the activity of protein kinases that are involved in cell growth and division. It has also been shown to inhibit the growth of prostate cancer cells by blocking the synthesis of testosterone, which is a hormone that promotes tumor growth. 2-Acetamido-N-benzyl-3-hydroxypropanamide is a potential candidate for developing new anticancer drugs due to its ability to selectively target cancer cells while sparing healthy cells.</p>

<p>CAS No. is a drug product that has been custom synthesized for research and development purposes. It is a white crystalline powder with a melting point of 256-258°C. Metabolism studies have shown that olsalazine sodium impurity E is metabolized to sulfapyridine, which is an active metabolite of olsalazine sodium. Impurity standard A has been synthesized as an analytical standard for HPLC analysis. This impurity standard exhibits the same retention time as olsalazine sodium in the HPLC system and can be used for the quantitative determination of this impurity in olsalazine sodium samples.</p>

<p>2-(4′-Chloro-2,3,4,5-tetrahydro-[1,1′-biphenyl]-4-yl)-3-hydroxynaphthalene-1,4-dione is a research and development impurity standard. It is a synthetic compound that is used as an impurity standard for the manufacture of drug product. 2-(4′-Chloro-2,3,4,5-tetrahydro-[1,1′-biphenyl]-4-yl)-3-hydroxynaphthalene-1,4-dione has high purity and can be used in pharmacopoeia and drug development studies to measure metabolism. 2-(4′-Chloro-2,3,4,5-tetrahydro-[1,1′-biphenyl]-4-yl)-3 -hydroxynaphthalene -1</p>