APIs for research and impurities

Intermediate in the synthesis of ribavirin

Please enquire for more information about o-Methyl malathion β-monoacid including the price, delivery time and more detailed product information at the technical inquiry form on this page

R-96544 Hydrochloride is an analytical standard used in HPLC analysis. It is also a metabolite of R-96544, which is an investigational drug for the treatment of schizophrenia. The impurity standard is a mixture of the racemic form and the pure enantiomeric form. This product is available in both natural and synthetic forms.

Mono(3-hydroxybutyl)phthalate-d4 is a research and development, impurity standard, custom synthesis, drug product, synthetic and high purity chemical that is used as an analytical standard in the pharmacopoeia. Mono(3-hydroxybutyl)phthalate-d4 is also a metabolite of monobutyl phthalate. This product has been shown to be an active substrate for human cytochrome P450 enzymes and has been used to study the metabolism of this compound. Mono(3-hydroxybutyl)phthalate-d4 can be synthesized from commercial chemicals such as pivalic acid, naphthalene or 2-(2'-methylpropoxy)-ethanol with butyric acid in the presence of aluminum chloride. The CAS number for this compound is 57074-43-8 and it should be stored at -20°C.

(-)-Cloprostenol is an analog of prostaglandin F2α and a potent inhibitor of protein kinase C. It has been shown to induce apoptosis in human cancer cells, making it a potential anticancer agent. (-)-Cloprostenol has also demonstrated inhibitory effects on tumor growth in Chinese hamster ovary cells and has been investigated for its medicinal uses in cancer treatment. This compound works by binding to the prostaglandin receptor and activating downstream signaling pathways that lead to cell death. Its ability to inhibit kinases makes it a promising candidate for the development of kinase inhibitors as a new class of anticancer drugs.

Methotrexate-5-monomethyl ester is an analytical standard that is synthesized synthetically. The synthetic route used to produce the compound has been optimized for high purity, making this product suitable for use as a drug product or impurity standard. The structure of methotrexate-5-monomethyl ester was confirmed by 1H and 13C NMR spectroscopy and mass spectrometry. Methotrexate-5-monomethyl ester is an impurity found in the synthesis of methotrexate and is a metabolite of methotrexate. It has been shown to inhibit DNA synthesis and protein synthesis in animal cells, which may be due to its ability to inhibit transcription factors such as NFATc1, NFkB, STAT3, STAT5A and STAT5B.

Alanycarb is a potent protein kinase inhibitor that has shown promising results in the treatment of cancer. It works by inhibiting the activity of kinases, which are enzymes that play a crucial role in cell growth and proliferation. Alanycarb induces apoptosis, or programmed cell death, in cancer cells and has been found to be particularly effective against tumors that are resistant to other anticancer drugs. This analog of cellulose has been tested on human and Chinese urine cancer cells and has shown significant tumor inhibition effects. Alanycarb is one of the most promising inhibitors for the development of new anticancer drugs due to its potent activity against various types of cancer cells.

DRI-c21045 is an analog of a medicinal compound that has been shown to inhibit the activity of a specific protein kinase involved in cell cycle regulation and tumor growth. This inhibitor has been demonstrated to induce apoptosis in cancer cells, making it a promising candidate for anticancer therapy. DRI-c21045 has been tested in both Chinese and human cancer cell lines and has shown potent activity against various types of tumors. Additionally, this compound has been detected in urine samples from patients with cancer, suggesting that it may have potential as a diagnostic marker for certain types of cancer. Overall, DRI-c21045 shows great promise as a potential anticancer agent with significant therapeutic potential.

3-(3-Trifluoromethylphenyl)propionaldehyde diethylacetal is a synthetic compound that belongs to the class of drug products. It is used for research and development, as well as for developing analytical standards for HPLC. This product has been shown to be metabolized in the rat liver by hydrolysis of the acetal group and oxidation of the alcohol.

Pyrimisulfan is a medicinal compound that has shown potent anticancer activity in both human and Chinese hamster cancer cell lines. It is an analog of pyrimidine, a naturally occurring compound found in urine. Pyrimisulfan works by inhibiting the activity of protein kinases, which are enzymes that regulate cell cycle progression and promote cell growth. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. Pyrimisulfan has been shown to be a highly selective inhibitor of certain protein kinases, making it a promising candidate for the development of targeted cancer therapies. Its unique mechanism of action and specificity make it a valuable addition to the arsenal of anticancer inhibitors currently available.

Acyclovir Impurity K is a drug product that is used as an analytical reference standard for metabolism studies. Acyclovir Impurity K is a natural product and an impurity of acyclovir, which has CAS No. 1797131-64-6. The chemical name of this drug is 3-hydroxy-2,5,6,7-tetrahydro-1H-[1]benzopyran-2,4(3H)-dione. It can be synthesized in the laboratory by custom synthesis or it can be obtained from a commercial supplier as an impurity standard. This product is used to help with drug development and research and development in the pharmaceutical industry. It can also be used as a high purity HPLC standard for pharmacopoeia testing purposes.

Granisetron is a serotonin 5-hydroxytryptamine 3 (5-HT3) receptor antagonist. It is used in the prevention and treatment of nausea and vomiting caused by cytotoxic chemotherapy, radiation therapy, or surgery. Granisetron hydrochloride is a white to off-white powder with a molecular weight of 476.0. The chemical formula for granisetron hydrochloride is C22H24ClN2O2S. This drug has been shown to be efficient in the prevention and treatment of nausea and vomiting caused by cytotoxic chemotherapy, radiation therapy, or surgery. The potential impurities are as follows:
1) 1-Desmethyl 2-methyl granisetron
2) 2-Methyl granisetron
3) 2-Methyl 3-(4'-hydroxyphenyl)propionitrile
4) 2-(4'-Hydroxyphenyl)-3-(

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Methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-alpha-D-glucopyranoside is an impurity of Dapagliflozin.

S(-)-BZM is a potent kinase inhibitor that has been shown to induce apoptosis in cancer cells. It is an analog of the natural product staurosporine and has been isolated from human urine. S(-)-BZM inhibits the activity of several kinases, including protein kinase C and cyclin-dependent kinases, which are involved in cell cycle regulation and tumor growth. This drug has been tested on various cancer cell lines, including leukemia, and has demonstrated significant antitumor activity. S(-)-BZM is a promising medicinal agent for the treatment of cancer and other diseases characterized by abnormal cell proliferation.

Solifenacin N-oxide is an anti-cholinergic agent that has been shown to be effective in the treatment of overactive bladder. Solifenacin N-oxide is a prodrug that is hydrolyzed in vivo to solifenacin, its active form. The compound reversibly binds to muscarinic receptors and inhibits the release of acetylcholine. Solifenacin N-oxide has been shown to have low levels of impurities and is highly soluble in water. It was also found to be stable when stored at room temperature for two months. This drug has a high flow rate and moderate retention time, which makes it suitable for reversed-phase liquid chromatography (RPLC). RPLC is a chromatographic technique that separates compounds by size, hydrophobicity, or charge.

Desgadolinium gadoteridol is a contrast agent that is used in magnetic resonance imaging (MRI). It is a gadolinium-based contrast agent that contains an ester linkage. The chelate complex of gadolinium with desgadolinium has been shown to have high water permeability and target tissue affinity, as well as low toxicity. Desgadolinium gadoteridol is used to diagnose inflammatory bowel diseases by determining the thickness of the bowel wall. This agent may also be used to evaluate blood pressure and diagnose hemorrhoids or colorectal polyps.

Aceclofenac ethyl ester is a prodrug of diclofenac. It is a non-steroidal anti-inflammatory drug that alleviates the symptoms of pain, stiffness, and swelling. It exerts its effects by inhibiting prostaglandin synthesis in the central nervous system and peripheral tissues. Aceclofenac ethyl ester has minimal systemic absorption when administered orally, which reduces the risk of side effects such as stomach upset and kidney damage. The pharmacopoeia provides an efficient method for preparing this compound by reacting diclofenac with magnesium stearate in a solvent containing an organic amine or alcohol at temperatures below 50°C (122°F). Aceclofenac ethyl ester may contain impurities such as benzyl alcohol, polyvinylpyrrolidone, or magnesium stearate.

Ethosuximide impurity A is a fluorinated compound that inhibits the enzyme acetylcholinesterase. It has been shown to inhibit the catalytic mechanism of acetylcholinesterase, which leads to its inhibitory effect on the enzyme. The compound does not have any structural similarity to the other known inhibitors of this enzyme. Ethosuximide impurity A has been shown to be an antimutagen and anticarcinogen in vitro, with a postulated mechanism of action that involves inhibition of a water molecule from binding to the active site.

Surfactin is a cyclic lipopeptide that has been found in urine and has shown potential as an anticancer agent. It has been shown to inhibit kinases, including indirubin and Chinese hamster ovary cell tumor kinase, which are involved in cancer cell proliferation. Surfactin analogs have also been developed as inhibitors of cancer cell growth and inducers of apoptosis. In addition to its anticancer properties, surfactin has been found to have antimicrobial activity against a variety of bacteria, including Clostridium perfringens. Overall, surfactin shows promise as a multifunctional therapeutic agent with potential applications in both cancer treatment and microbial control.

25-Hydroxyvitamin D2 3-hemisuccinate is a drug product that belongs to the group of natural products. It is a metabolite of vitamin D2 and has been shown to have anti-inflammatory properties. 25-Hydroxyvitamin D2 3-hemisuccinate is used as an analytical standard for HPLC, but it is also used in research and development for drug development. This product can be used as an impurity standard for API's because it is easily purified and stable in storage. Research has shown that this compound may be effective in protecting against osteoporosis, cardiovascular disease, and cancer.

4-Carboxy-3-ethoxy)phenyl acetic acid (CPAE) is a fluorescent compound that has been shown to have antidiabetic and luminescence properties. It absorbs light at wavelengths of 340, 405, and 455 nm and emits light at 525 nm. It also absorbs UV light at 310 nm and emits fluorescence at 495 nm. CPAE is formed by the condensation of two molecules of 4-carboxybenzaldehyde with one molecule of ethyl 3-ethoxypropanoate in the presence of a base. The crystals are monoclinic, with space group P2/c and lattice constants a = 12.872(1) Å, b = 7.319(1) Å, c = 17.814(2) Å, β = 98.664(9)°, Z = 2. The molecular weight is 182.24 g/mol and its molecular

Isoleucine valsartan is a drug product that is chemically synthesized from the natural amino acid isoleucine. The chemical synthesis of this drug product is carried out in an impurity-free environment and under strict quality control. Isoleucine valsartan has been developed for research and development purposes and as an analytical standard. It can be used for the production of high purity, pharmacopoeia grade API or as an impurity standard for HPLC analysis.

SAR131675 is a small molecule that potently inhibits angiotensin converting enzyme (ACE) and angiotensin receptor type 1 (AT1). SAR131675 selectively blocks the kinase activity of ACE, thereby inhibiting the production of Ang II. This drug has shown anticancer activity in vitro by inducing apoptosis in cancer cells. SAR131675 also has anti-herpes simplex virus activity, which may be due to its ability to inhibit viral DNA synthesis and/or stimulate cell death.