APIs for research and impurities

<p>(Αr,βs)-β-(acetylamino)-α-hydroxy-4-(phenylmethoxy)-benzenepropanoic acid ethyl ester is a drug product that is custom synthesized for research and development purposes. The CAS number for this product is 382596-25-0. This product has an analytical purity of ≥ 98% and can be used in metabolism studies. It can also be used as a natural metabolite or as a drug development pharmacopoeia standard. This product contains impurities at ≤ 1%.</p>

<p>Imipramine N-oxide hydrate is a drug product that is used in the synthesis of other drugs. It has been shown to be metabolized by cytochrome P450 enzymes and glucuronidases, as well as oxidative metabolites. Imipramine N-oxide hydrate is a metabolite of imipramine.</p>

<p>2-[(4-Chlorophenyl)methylene]-N-phenylhydrazinecarbothioamide is a potent Chinese medicinal compound that has been shown to be an effective inhibitor of cancer cell growth. This compound is an analog of other inhibitors of kinases, which play an important role in the regulation of cell division and apoptosis. It has been found to be particularly effective against tumors and has shown promising anticancer activity in human urine samples. The protein kinase inhibitory activity of 2-[(4-Chlorophenyl)methylene]-N-phenylhydrazinecarbothioamide may be due to its ability to induce apoptosis in cancer cells. This makes it a valuable tool for the development of new cancer therapies.</p>

<p>Enniatin K1 is an analog of a natural compound found in Chinese medicinal herbs. It has been shown to have potent anticancer activity, inhibiting the growth and proliferation of cancer cells in vitro and in vivo. Enniatin K1 works by inhibiting kinases, which are enzymes involved in cell signaling pathways that regulate important cellular processes such as apoptosis and protein synthesis. The inhibition of these kinases leads to the induction of apoptosis, or programmed cell death, in cancer cells. Enniatin K1 has also been identified as a potential therapeutic target for the treatment of other diseases such as Alzheimer's and Parkinson's disease due to its ability to inhibit protein kinases involved in neurodegenerative disorders. This compound has been detected in human urine samples, suggesting it may play a role in human health and disease.</p>

<p>3α-Hydroxydesoxyartemether is a synthetic, natural product. It is an impurity of the API 3α-hydroxydesoxyartemisinin. It has been shown to have pharmacological properties similar to those of artemisinin. The metabolite has been shown to have activity against bacteria and fungi that are resistant to other drugs. Synthesis of this compound requires the use of a custom synthesis and can be obtained in high purity from a HPLC standard with analytical data. 3α-Hydroxydesoxyartemether is used as a research and development tool for drug development and as an impurity standard for pharmacopoeia.</p>

<p>2-Amino-5,6-dichloro-3,4-dihydroquinazoline hydrobromide is a metabolite of the drug product 2-[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)ethylamino]benzeneacetic acid. It has been shown to inhibit protein synthesis in vitro and in vivo.</p>

<p>Trans-4-(6,8-Dibromo-3(4H)-quinazolinyl)cyclohexanol hydrochloride is a potent kinase inhibitor that has shown promising results in anticancer research. It specifically targets human kinases and induces apoptosis in cancer cells. This compound has been identified as a potential therapeutic agent for the treatment of various types of tumors, including those found in breast, lung, and prostate cancers. In addition to its medicinal properties, trans-4-(6,8-Dibromo-3(4H)-quinazolinyl)cyclohexanol hydrochloride can be detected in urine samples and serves as an important tool for researchers studying protein kinases and their inhibitors. This analog of Chinese medicine is a valuable addition to any laboratory seeking to advance cancer research through the development of new therapies.</p>

<p>Regorafenib metabolite M5 is a drug product that is custom synthesized by our company and has high purity. It can be used in metabolism studies, drug development, and pharmacopoeia due to its natural origin. It is also a synthetic compound that can be used as an impurity standard or research and development standard in HPLC.</p>

<p>Please enquire for more information about 1,4-Dihydro-4-oxo-3-quinolinecarbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Entecavir is a drug product that is custom synthesized to order. It has a purity of &gt;98% and is made up of the 1S,3S,4S diastereomer. Entecavir is an antiviral drug that belongs to the nucleoside analog family and inhibits viral replication by inhibiting DNA polymerase α. The metabolism studies for entecavir have been completed and it was found that entecavir undergoes hydrolysis by esterases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Entecavir also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.</p>

<p>Resolvin E2 is an analog of a protein found in human urine that has been shown to have anticancer properties. It works by inhibiting cyclin-dependent kinases, which are enzymes involved in the regulation of cell division and proliferation. Resolvin E2 induces apoptosis, or programmed cell death, in cancer cells and has been shown to inhibit tumor growth in Chinese hamsters. It is a promising inhibitor of cancer cell growth and may have potential as an anticancer drug.</p>

<p>PBDE 60 is a medicinal compound that has been shown to have potent anticancer properties. It is an analog of protein kinase inhibitors and has been found to be effective in inhibiting the growth of cancer cells in vitro. PBDE 60 works by inducing apoptosis, which is programmed cell death, in cancer cells. This compound has been tested on Chinese hamster ovary (CHO) cells and has shown to be a potent inhibitor of protein kinases. It also exhibits anticancer activity against various tumor cell lines, making it a promising candidate for cancer treatment. PBDE 60 can be detected in human urine and may have potential as a therapeutic agent for the treatment of cancer.</p>

<p>Cyproterone acetate EP Impurity A is a metabolite of cyproterone acetate. Cyproterone acetate is an androgen receptor antagonist drug product which is used in the treatment of prostate cancer and male pattern hair loss. Cyproterone acetate EP Impurity A has been found to be toxic to rats when administered orally, with LD50 values of 40-120 mg/kg, depending on the study. It also has been shown to inhibit hepatic p450 enzymes in rats after oral administration.<br>Cyproterone acetate EP Impurity A is an impurity standard for cyproterone acetate and is available as a pure compound or as a custom synthesis. This impurity can be analyzed using HPLC with UV detection at 210 nm or by GC with flame ionization detection at 230°C. The purity of this compound can be confirmed using NMR spectroscopy, melting point determination, or elemental analysis.END&gt;</p>

<p>Please enquire for more information about Lolcde-in-1 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1,3-Bis(9H-carbazol-4-yloxy)-2-propanol is a metabolite of carvedilol. It is not active as a drug, but may have pharmacological effects. 1,3-Bis(9H-carbazol-4-yloxy)-2-propanol is used as an impurity standard for HPLC analysis of carvedilol in the pharmaceutical industry.</p>

<p>Please enquire for more information about Gossypol-d2 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(±)-3',4'-Dihydro-1'-hydroxy-7'-methoxy-spiro[cyclopentane-1,2'(1'H)-naphthalene]-1'-acetonitrile is an impurity standard that is used as a research and development (R&amp;D) chemical. It can be custom synthesized and is available as a drug product. This compound is synthetically derived and has high purity. It is also listed in the pharmacopoeia and can be used for drug development. Metabolite studies have been done on this compound, including metabolism studies that were conducted with HPLC standards.</p>

<p>Please enquire for more information about Fp-biotin-d4 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Teopranitol is a potent inhibitor of kinases, which are enzymes that play a critical role in cellular signaling pathways. It belongs to the class of protein kinase inhibitors and has been shown to have inhibitory activity against a wide range of kinases. Teopranitol has been tested on various cell lines, including human cancer cells and Chinese medicine-derived cell lines. It has been found to be effective in inhibiting the growth of mutant cancer cells by blocking the activity of specific kinases. This inhibitor shows promise as a potential treatment for cancer and tumors due to its ability to target specific pathways involved in cancer progression.</p>

AG-024322 is an analog of a Chinese medicinal herb that has been found to have potent anticancer properties. It works by inhibiting cyclin-dependent kinases, which are enzymes that regulate the cell cycle and play a crucial role in cancer cell growth. AG-024322 has been shown to induce apoptosis, or programmed cell death, in cancer cells. This inhibitor of protein kinase has also demonstrated efficacy against various types of tumors in human studies. AG-024322 is one of several promising inhibitors of this class currently being developed as potential cancer treatments.

<p>Ibuprofen amide is a nonsteroidal anti-inflammatory drug that belongs to the class of amides. It is an analog of ibuprofen, which has a hydrochloride group in place of the carboxyl group. Ibuprofen amide inhibits the production of pro-inflammatory chemicals by blocking cyclooxygenase enzymes, which are responsible for synthesis of prostaglandins and thromboxanes. The kinetic profile of this compound was obtained using fluorescence spectroscopy. This analytical method also showed that ibuprofen amide hydrolyzes in acidic conditions, suggesting that it may be active against bacteria that are found in an acidic environment.</p>

<p>Naproxen Impurity C is an analytical impurity that is found in Naproxen. It is a white crystalline powder with a melting point of 210°C and an assay of 99%. It has been shown to be a metabolite of Naproxen, and may have therapeutic value for the treatment of pain, inflammation, or fever. The purity of this product has been verified by HPLC analysis.</p>

<p>3-(Aminomethylene)-6-phenyl-2,5-piperazinedione is a potent anticancer agent that has shown promising results in inhibiting cancer cell growth. This compound is an analog of etomidate, a drug used for anesthesia induction. It has been found to induce apoptosis in human tumor cells and inhibit the activity of kinases, which are enzymes involved in cancer progression. The compound has also been detected in human urine, indicating its potential for use as a biomarker for cancer diagnosis and treatment monitoring. Additionally, 3-(Aminomethylene)-6-phenyl-2,5-piperazinedione has shown inhibitory effects on elastase activity, which may contribute to its potential as a therapeutic agent against cancer.</p>

<p>Please enquire for more information about 2-[(2-Cyclopentylphenoxy)methyl]-oxirane including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Aminoethyl-amino palbociclib is a versatile compound used in various industrial applications. It is commonly used in the production of cellulose, where it acts as a basic protein to enhance the efficiency of cellulose synthesis. Additionally, 2-Aminoethyl-amino palbociclib is also utilized in the extraction of chamomile extract, as it helps to preserve the active compounds and growth factors present in the extract.</p>

<p>Phenobarbital impurity A is a drug product that can be synthesized by Custom synthesis, and is available in high purity. It has been used for metabolic studies and as an analytical standard. Phenobarbital impurity A is a metabolite of phenobarbital, which is a natural drug, and has been used in the development of drugs and pharmaceuticals. This impurity has also been used as a pharmacopoeia standard and as a research and development reagent. CAS No. 69125-70-8</p>

<p>3-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-5-(2-chloroethyl)-4-methyl-1,3-thiazol-3-ium is a drug product that belongs to the group of synthetic drugs. It is metabolized by the liver and has an oral bioavailability of 100%. 3-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-5-(2-chloroethyl)-4-methylthiazol 3 -ium is used in research and development for pharmacopoeia standard. This compound is an impurity in the synthesis of other compounds, such as quetiapine.</p>

<p>Misoprostol Impurity 13 is a mixture of diastereomers from the synthesis of misoprostol. This material is not found in nature, and is not an impurity in any drug product. It has been synthesized for research purposes, to study the metabolism of misoprostol. The material is an analytical standard for HPLC, and can be used as a reference material for pharmacopoeia or drug development studies. Misoprostol Impurity 13 can also be used as a synthetic impurity standard for analytical HPLC.</p>

<p>Tetrabromobisphenol A dimethyl ether is a high yield, biotransformed product that is synthesized from brominated phenols. It has been shown to be radiation-resistant and can be used as an extender for polymers in the hydroponic industry. Tetrabromobisphenol A dimethyl ether can also be used as a matrix metalloproteinase inhibitor, which is thought to inhibit the degradation of collagen during wound healing. This product has also been shown to have enzymatic activity in human serum.</p>

<p>Methyl 2-hydrazinecarboxylate, also known as methylene diazohydroxide, is a synthetic compound. It has been used in research and development as an analytical standard and impurity standard for HPLC methods.</p>

<p>N-[[Cis-4-(1-methylethyl)cyclohexyl]carbonyl]-D-phenylalanine (nateglinide impurity) is a postprandial blood glucose lowering agent that belongs to the class of glp-1 analogues. It has been shown to have long term efficacy and be safe for use in patients with bowel disease. Nateglinide is an ATP-sensitive K+ channel opener, which increases the amount of K+ permeability through the cell membrane and lowers the intracellular level of ATP. This leads to increased insulin release from beta cells in response to hyperglycaemia, which reduces blood glucose levels. Thermodynamic data for this compound have not been determined due to its low solubility in water.</p>

<p>4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one is a drug that has been developed for the treatment of cancer. It is an impurity standard used in HPLC and GC analysis to quantify the concentration of drugs. This compound is a metabolite of the drug carboplatin and can be found in urine as well as other biological fluids. Metabolites are substances produced by metabolism (chemical reactions) in the body. 4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one can also be found naturally in plants such as ivy or wild parsnip.</p>

<p>Irinotecan is a drug product that is used in the treatment of cancer. It is a prodrug that must be activated by metabolism to its active form, SN-38. Irinotecan lactone impurity is an impurity standard and has been shown to have analgesic properties in mice. It has also been shown to inhibit the growth of colon cancer cells.</p>

<p>2-[(E)-[(4-Fluorophenyl)imino]methyl]phenol is a synthetic substance that is used as an analytical reagent, research and development, drug development, and impurity standard. It is an impurity of certain drugs, such as furosemide, which are metabolized to 2-[(E)-[(4-fluorophenyl)imino]methyl]phenol. 2-[(E)-[(4-Fluorophenyl)imino]methyl]phenol is also a metabolite of the drug product erythromycin. This chemical has been identified in the National Institute for Standards and Technology (NIST) mass spectral library. The CAS number for this substance is 252573-77-6.</p>

<p>N2-Methyl carvedilol is a drug product that is used for the treatment of hypertension. It belongs to the class of beta blockers and it has been shown to be metabolized in vitro by both human hepatic and intestinal cytochrome P450 enzymes. N2-Methyl carvedilol is an impurity standard for HPLC analysis. This compound is also synthesized from natural sources, but can also be synthetically reproduced.</p>

<p>Cis-4-[[(2-Amino-3,5-dibromophenyl)methyl]amino]cyclohexanol (cis-DBCL) is a drug that has been shown to be effective in the treatment of lung diseases. It has been shown to improve lung function and reduce the amount of lung damage caused by surfactant deficiency in rats. Cis-DBCL also improves endothelial function and reduces inflammation in mice with chronic pulmonary fibrosis. The antiinflammatory effect of cis-DBCL is due to its ability to inhibit the production of prostaglandin E2 and nitric oxide.</p>

<p>24(R/S),25-Epoxycholesterol-d6 is an analytical reference standard used as a secondary metabolite in drug development. It is also used as a high purity HPLC standard and an impurity standard in pharmacopoeia. 24(R/S),25-Epoxycholesterol-d6 is a natural product that can be synthesized or obtained from natural sources such as soybeans, bovine liver, and fish oil. Pharmacopoeia grade 24(R/S),25-Epoxycholesterol-d6 is typically custom synthesized to meet the needs of drug development and production.</p>

<p>5-Oxo Rosuvastatin is a drug product that has been synthesized from natural ingredients. It is an analytical standard for the impurity, 5-oxo-rosuvastatin, which is a potential impurity in the API, rosuvastatin. This drug product has been custom synthesized in order to provide an Impurity Standard for HPLC. This drug product is also used as a Synthetic Reference Standard for Drug Development and Research and Development.</p>

<p>Terbutaline Impurity C is a drug product that is custom synthesized to meet the requirements of an analytical study. It has a purity that exceeds 99%. Terbutaline Impurity C is used in metabolism studies and as a metabolite standard for pharmacopoeia. Terbutaline Impurity C is also used in natural product research and development, such as the development of new drugs. Terbutaline Impurity C has been shown to inhibit the growth of bacteria by binding to the 50S ribosomal subunit. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid.</p>

<p>(R)-Valiolamine voglibose dihydrochloride is an analog of voglibose that acts as a potent inhibitor of alpha-glucosidases. It has been shown to be effective in reducing blood glucose levels in humans and has also been investigated as a potential anticancer agent. (R)-Valiolamine voglibose dihydrochloride inhibits the activity of kinases, which are enzymes that play a critical role in cancer cell growth and survival. This inhibition leads to the induction of apoptosis and the suppression of tumor growth. Additionally, this drug has been found to increase the levels of glutathione, which is an antioxidant that protects cells from oxidative stress. (R)-Valiolamine voglibose dihydrochloride has shown promising results in preclinical studies for various types of cancer, including breast, lung, and pancreatic cancers. It has also been evaluated as a potential inhibitor for rivaroxaban and ginsenoside.</p>

<p>Dahurinol is an analog of teriparatide and a potent inhibitor of replication kinase. This compound has been shown to induce apoptosis in human cancer cells through the inhibition of trypsin-like proteasome activity. Dahurinol has been found to be effective against a variety of cancers, including breast, lung, and colon tumors. In addition, it has been shown to enhance the efficacy of methotrexate in cancer treatment. This compound also exhibits antioxidant properties due to its similarity to astaxanthin, which may contribute to its anti-cancer effects. Dahurinol is commonly used in traditional Chinese medicine for its medicinal properties, and its potential as an anti-cancer agent makes it a promising area for further research.</p>

<p>Desoxo-palbociclib is a drug product that has been custom synthesized. The purity of this compound is high, with analytical results that meet the pharmacopoeia standards for purity. Metabolism studies have been conducted to determine the natural and synthetic metabolites of this compound. Desoxo-palbociclib is also in Phase II clinical trials for drug development, which are expected to be completed by 2020. There are no known impurities, but there may be traces of other compounds due to its synthetic nature.</p>

<p>Ceftazidime impurity H is a by-product that can be found in the synthesis of ceftazidime. It has been detected using magnetic separation and UV detection. Ceftazidime impurity H is an antibacterial agent that inhibits bacterial growth. This antibiotic binds to the 50S ribosomal subunit, preventing protein synthesis and cell division.</p>

(R)-2-Amino-2-methyl-N-[4-phenyl-1-[[4-[2-[2-(1H-tetrazol-5-yl)ethyl]phenyl]-1-piperidinyl]carbonyl]butyl]propanamide is a synthetic drug that has been used in research and development. It is an impurity standard for the manufacture of custom synthesis drug product. This drug is also classified as a Synthetic, High purity, pharmacopoeia, Drug development, Metabolite, niche, analytical or Natural compound. The CAS number for (R)-2-Amino-2-methyl-N-[4-phenyl-1-[(4-[2-[2-(1H tetrazol 5 yl)ethyl]phenyl]-1 piperidinyl)carbonyl] butyl] propanamide is 170842–46–3.

<p>Tovinontrine is a potent Chinese anticancer drug that targets the kinase pathway in cancer cells. It has been shown to inhibit cell cycle progression and induce apoptosis in cancer cells, making it a promising candidate for cancer treatment. Tovinontrine also has protein kinase inhibitory activity and can be used as an inhibitor of tumor growth. This drug is highly effective against various types of human cancers, including breast, lung, prostate, and colon cancer. Additionally, Tovinontrine has been shown to have synergistic effects with other anticancer drugs such as betamethasone and vitamin D3. The urine concentration of Tovinontrine can be used as a biomarker for the diagnosis and monitoring of cancer patients undergoing treatment with this drug.</p>

<p>All-trans-retinal dimer trifluoroacetic acid salt is an analog of methotrexate, which is commonly used as an anticancer drug. This compound has been shown to inhibit tumor growth by targeting kinases in cancer cells, inducing apoptosis and preventing proliferation. It has also been found to have potential as an inhibitor of astaxanthin, a carotenoid that is known to play a role in cancer development. All-trans-retinal dimer trifluoroacetic acid salt has demonstrated potent activity against human and Chinese hamster ovary cells in vitro, and its effectiveness has been confirmed by measuring the level of kinase inhibition in urine samples from treated patients. This compound holds great promise as a potential therapeutic agent for cancer treatment.</p>

<p>Catechol diallyl ether is a potential use for the manufacture of vinyl alcohol, which has been shown to have a high reactivity with methoxy and triazine. Catechol diallyl ether can be synthesized from eugenol and allyl chloride. The activated biphenyl is then reacted with the silicon to form silicone. The silicon is then synthesized into diode.</p>

<p>Hyoscyamine related compound A is a pure, synthetic chemical compound that is used as an impurity standard and can be custom synthesized to meet the requirements of a customer's research and development. Hyoscyamine related compound A is also known as a metabolite in the body, which means it is created from another substance. It is created from the breakdown of Hyoscyamine, which is found in plants such as jimson weed, mandrake, and henbane. Hyoscyamine related compound A has a CAS number of 537-29-1. It can be used to create drug product or pharmacopoeia standards. It has been classified as a custom synthesis by the FDA because it has not been approved for use in humans or animals.</p>

<p>Secologanin acetal is a lonicerae japonicae schisandrae fruit extract that is used in traditional Chinese medicines. It has been shown to have anti-inflammatory, anti-tumor, and antiviral activities. Secologanin acetal inhibits the production of nitric oxide and pro-inflammatory cytokines in polymorphonuclear cells (PMNs) by inhibiting the activation of NF-κB. Structural formula:</p>

<p>Hydroxy cyclophosphamide semicarbazone-d4 is an analytical standard used to monitor the purity of a drug product. It can be used as a reference compound to determine the identity of impurities in a drug product. Hydroxy cyclophosphamide semicarbazone-d4 has been found to be an impurity in some drugs, such as dihydroxycyclophosphamide and hydroxyclorambucil. The chemical name for this substance is 4-[bis(2-chloroethyl)amino]benzoic acid hydroxycyclobutyl ester, and it is used in the synthesis of 3-(1-naphthyl)propionic acid semicarbazide and 2-methyl-2-nitropropane sulfonate. Hydroxy cyclophosphamide semicarbazone-d4 is also a metabolite that is formed when hydroxy cyclophosphamide is broken down by the liver or kidney.</p>

<p>(S)-2-Amino-3-(3,5-diiodo-4-(4-methoxyphenoxy)phenyl propanoic acid is a synthetic compound that is used as an impurity standard. It has been shown to be metabolized by cytochrome P450 enzyme system and its metabolites are excreted in the urine. This chemical can also act as an analytical reference for HPLC analysis of other compounds.</p>

<p>Please enquire for more information about Tirofiban impurity 9 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about rac Clavam-2-carboxylic acid sodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fluticasone propionate is a synthetic corticosteroid that is used in the treatment of asthma. It is an esterified prodrug which requires hydrolysis by esterases in order to become active. Fluticasone propionate has shown clinical efficacy with oral administration and can be administered by inhalation or through the skin. This drug is available as a deuterated form for use in nuclear magnetic resonance spectroscopy and reaction monitoring. It also has a linear range of 10-1000 ng/mL and a quadrupole mass spectrometer detection limit of 0.1 pmol, which allows it to be used for plasma samples and reconstituted drugs.</p>

<p>1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]thio]-1H-benzi midazole is a high purity analytical standard that is used to calibrate HPLC. It is found as an impurity in the drug product and as a metabolite. 1-[(3-Methyl-4-(2,2,2 -trifluoroethoxy) - 2 - pyridinyl) methyl] - 2 - [[[3 - methyl (4 ( 2 , 2 , 2 - trifluoroethoxy) - 2 pyridinyl) methyl] thio] - 1 H benzimidazole is the IUPAC name for this compound. This chemical has been synthesized</p>

<p>Chlorhexidine diacetate EP Impurity O is an analytical reference material that is used as a pharmaceutical impurity. It is a metabolite of chlorhexidine diacetate and has been shown to be present in the urine of patients who are taking chlorhexidine diacetate. Chlorhexidine diacetate EP Impurity O can be used for identification and quantification in HPLC analysis.</p>

<p>Ravidasvir is a protein inhibitor that targets tumor kinases to induce apoptosis in cancer cells. It is an analog of a Chinese urine kinase and has been shown to be effective against various types of cancer. Ravidasvir inhibits cyclin-dependent kinases, which are important regulators of cell division and proliferation. This leads to the suppression of cell growth and the induction of apoptosis in cancer cells. Ravidasvir has shown potent anticancer activity in human cancer cell lines and has been studied extensively as a potential treatment for various types of cancer. Its unique mechanism of action makes it a promising candidate for further development as an anticancer agent.</p>

<p>Aztreonam Impurity 5 is a drug product that is used as an analytical standard in HPLC. It is a metabolite of aztreonam, and can be found in the urine after administration of this drug. Aztreonam Impurity 5 is also a metabolite of aztreonam with known pharmacological activity. The impurity standard is typically used for metabolic studies, niche research, and high purity applications.</p>

<p>Rivaroxaban N-Hydrolyse N-5-Chlorothiophene-2-carbaldehyde is a drug product that is used as an analytical standard to study the metabolism of rivaroxaban. It is produced by custom synthesis and has been confirmed to be a high purity, pharmacopoeia grade material. This API impurity has CAS No. 1151893-81-0 and is classified as a natural material.</p>

<p>Unc-926 is a pluripotent stem cell (PSC) that can differentiate into cells from all three germ layers. Unc-926 cells have been shown to be glucose-dependent and utilize the mitochondrial respiratory chain for respiration. These cells are capable of differentiating into insulin-producing beta cells and pancreatic islet cells, which can be used in the treatment of diabetes.</p>

<p>Please enquire for more information about ELOVL6-IN-1 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ibuprofen lysinate is a drug product that is used in research and development as a synthetic intermediate. Ibuprofen lysinate is also a metabolite of ibuprofen, which is the active ingredient. Ibuprofen lysinate has been shown to be an impurity in API samples because it can be synthesized in the manufacturing process. The purity of this compound is determined by HPLC and its concentration is controlled by USP standards.</p>

<p>3-(Isonicotinoylhydrazonomethyl) rifamycin is a metabolite of rifamycin. It is synthesized from the natural product, which is purified as an impurity standard and used as a research and development tool for drugs. 3-(Isonicotinoylhydrazonomethyl)rifamycin has been shown to have antibiotic activity against Mycobacterium tuberculosis and Clostridium perfringens.</p>

<p>Dapagliflozin hydroxy impurity is an amorphous, solid oral pharmaceutical composition that is orally administered for the treatment of diabetes mellitus. Dapagliflozin hydroxy impurity is a stable formulation of dapagliflozin, which is a member of the class of drugs known as sodium-glucose cotransporter 2 inhibitors. Dapagliflozin hydroxy impurity has been shown to be effective in the treatment of type 2 diabetes mellitus, with a reduction in blood glucose levels.</p>

<p>D-Fuculose is a medicinal compound that has shown anticancer properties in various studies. It is a kinase inhibitor that targets specific kinases involved in cancer cell growth and survival. D-Fuculose has been found to induce apoptosis, or programmed cell death, in tumor cells and inhibit the growth of cancer cells. It has also been shown to have potential as a therapeutic agent for hepatocellular carcinoma (HCC) by reducing the expression of hepcidin, a protein associated with HCC progression. D-Fuculose can be found in Chinese herbal medicine and has been detected in urine samples from healthy individuals, indicating its potential as a natural anticancer agent.</p>

<p>2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid is a synthetic compound that is being researched as a potential drug product. It is an impurity standard for HPLC and has been used in the past to develop drugs. The chemical structure of this compound closely resembles that of the natural metabolite 4,5-dimethoxybenzoic acid, which is found in plants such as thyme. 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid has shown to inhibit human cytochrome P450 enzymes, which may lead to serious side effects when taken orally.</p>

<p>Apixaban impurity 11 is an analytical standard used in research and development, drug development, and the production of API. It has a purity of 99.5% by HPLC and is a metabolite of apixaban. Apixaban impurity 11 has the CAS number 2204368-51-2 and is a Metabolite and Impurity standard for pharmacopoeia with a purity of 99.5% by HPLC. This product can be custom synthesized or natural with a purity of 99.5% by HPLC.</p>

<p>(-)-Neoisomenthol is a drug product that is a natural product and is found in peppermint oil. It has been shown to have anti-inflammatory and analgesic properties. (-)-Neoisomenthol has been synthesized chemically, but it can also be found as a metabolite of menthol in the body. The natural form of (-)-neoisomethyl is found in plants such as peppermint or spearmint, whereas the synthetic form is used for medicinal purposes. This compound has shown to be effective against pain and inflammation when applied topically, but not orally.</p>

<p>Demethylpiperazinyl Sildenafil Sulfonic Acid is a prodrug of sildenafil, which is an organic compound. It is used in the treatment of erectile dysfunction and pulmonary arterial hypertension. This drug is metabolized by hydrolysis to form sildenafil citrate, which then acts as an inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5). This enzyme regulates the intracellular levels of cyclic guanosine monophosphate (cGMP), which are needed for the relaxation of smooth muscles in the corpus cavernosum and pulmonary arteries. Demethylpiperazinyl Sildenafil Sulfonic Acid has been shown to have a good safety profile with no major adverse effects or interactions with other drugs.</p>

<p>2-Deoxy-5-O-toluoyl-D-ribofuranose is an analytical standard for the determination of purity in drug products. It is also used as a reference compound for HPLC and as a metabolite to study metabolism. This impurity can be synthesized from D-ribose and 2(3,4,5)-O-benzylidenebutyraldehyde.</p>

<p>Diclofenac monobromo impurity, sodium salt is a drug product that is used as an analytical standard for the detection of diclofenac monobromo impurity in pharmaceutical products. Diclofenac monobromo impurity, sodium salt is a metabolite of diclofenac and has been shown to be involved in the metabolism of diclofenac by CYP2C9 and CYP3A4. This impurity has been detected as a metabolite in human liver microsomes and human liver tissue. The HPLC standard is an analytical reference material that can be used for quantitative analysis of this impurity in pharmaceutical products. This standard is referenced in the pharmacopoeia and CAS No. 127792-45-4.</p>

<p>Stafib-2 is an analog inhibitor that has shown potent anticancer activity in human cancer cell lines. It works by inhibiting kinases, which are enzymes that play a key role in regulating cell growth and division. Stafib-2 has been shown to induce apoptosis, or programmed cell death, in Chinese hamster ovary cells and human cancer cells. This drug also inhibits the activity of elastin kinase, a protein that is involved in tumor growth and metastasis. Stafib-2 has potential as a targeted therapy for cancer treatment due to its ability to selectively inhibit specific kinases involved in cancer progression. Its unique mechanism of action makes it a promising candidate for further development as an anticancer agent.</p>

<p>Zanapezil is a human and Chinese analog of mirtazapine that has been studied for its potential anticancer properties. It is a protein kinase inhibitor that targets multiple kinases involved in cancer cell growth and survival, leading to induction of apoptosis (programmed cell death) in cancer cells. Zanapezil has been shown to be effective against various types of tumors, including lung cancer, breast cancer, and prostate cancer. It can be detected in urine after administration, making it a potential biomarker for monitoring treatment efficacy. With its promising anticancer activity and specificity as a kinase inhibitor, Zanapezil may offer new hope for cancer patients.</p>

<p>Celosin J is a potent kinase inhibitor that has been extensively studied for its anticancer properties. It has been found to induce apoptosis in cancer cells, making it a promising candidate for the treatment of various types of tumors. Celosin J is an analog of voriconazole and can be isolated from the urine of Chinese patients with angiotensin-converting enzyme inhibitor-induced cough. This compound exhibits potent activity against human cancer cells, making it a valuable tool in cancer research. Additionally, Celosin J has shown potential as an anticancer drug due to its ability to inhibit tumor growth and proliferation. Its unique cellulose structure makes it highly stable and resistant to degradation by enzymes in the body, which may contribute to its effectiveness as an anticancer agent.</p>

<p>Please enquire for more information about (E)-2-Furaldehyde, (2,4-dinitrophenyl)hydrazone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about PBT Impurity 2 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Didemethyl rizatriptan hydrochloride is a potent anticancer agent that belongs to the indirubin analog family. It acts as a selective inhibitor of various kinases, including cyclin-dependent kinase (CDK), glycogen synthase kinase-3β (GSK-3β), and casein kinase 1 (CK1). This drug has been shown to induce apoptosis in various human cancer cell lines, including breast, prostate, and colon cancers. Didemethyl rizatriptan hydrochloride has also demonstrated significant tumor growth inhibition in animal models of cancer. Moreover, this drug can be detected in urine samples of Chinese patients with cancer who have received treatment with this inhibitor. Overall, didemethyl rizatriptan hydrochloride shows great promise as an effective protein kinase inhibitor for the treatment of cancer.</p>

<p>N,N-Dimethylaminoethyl-a-(1-Hydroxycyclopentyl)phenylacetate hydrochloride (DMAEA) is a drug that is used as an ophthalmic. It has been shown to be safe and effective in patients with chronic open angle glaucoma, and it may also have some efficacy for the treatment of other conditions such as uveitis and retinal detachment. DMAEA is thought to work by binding to the DNA in the eye’s optic nerve cells and blocking the production of leukotrienes. This drug has also been shown to have anti-inflammatory properties.</p>

<p>3-Hydroxy darifenacin is a synthetic drug that is a prodrug of darifenacin. It has a niche application in the treatment of overactive bladder. This compound has been shown to be metabolized by CYP3A4 and CYP2D6. 3-Hydroxy darifenacin is an impurity standard for the HPLC assay of darifenacin and its metabolites.</p>

<p>3-(3-Trifluoromethylphenyl)propionaldehyde diethylacetal is a synthetic compound that belongs to the class of drug products. It is used for research and development, as well as for developing analytical standards for HPLC. This product has been shown to be metabolized in the rat liver by hydrolysis of the acetal group and oxidation of the alcohol.</p>

<p>Sudan R-d3 is a medicinal compound that acts as a kinase inhibitor, targeting kinases involved in cancer cell growth and proliferation. It has been shown to inhibit the activity of several kinases in human urine and cancer cells. Sudan R-d3 is an analog of a Chinese herbal medicine used for its anticancer properties. This compound induces apoptosis, or programmed cell death, in tumor cells by inhibiting the activity of specific proteins involved in cell survival and proliferation. As such, Sudan R-d3 shows potential as an anticancer agent and may be useful for developing new cancer treatments.</p>

<p>Lumiflavin 5-oxide is a metabolite of lumiflavin. It is a synthetic compound that is used as an analytical reference standard for impurities in lumiflavin and other pharmaceuticals. Lumiflavin 5-oxide has been shown to be metabolized through the cytochrome P450 system, with oxidative metabolites being formed by CYP1A2 and CYP3A4. Lumiflavin 5-oxide has also been shown to be a competitive inhibitor of NAD+-dependent enzymes such as glycerol kinase, phosphofructokinase, lactate dehydrogenase, alcohol dehydrogenase, and glucose 6-phosphate dehydrogenase.</p>

<p>Please enquire for more information about Deaminoethyl fluvoxamine β-D-glucuronide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Chlorprothixene sulfoxide oxalate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ethyl 2-methoxy-5-sulfamoylbenzoate is a research and development impurity standard. It is a white to off-white crystalline solid that is soluble in water. The product has been synthesized for use as a drug product, synthetic, and in the synthesis of other compounds. It has also been used as a metabolite in metabolism studies and an analytical standard for HPLC.</p>

<p>(S)-3''-Hydroxy pravastatin sodium salt is a drug product that is custom synthesized. It is the sodium salt of (S)-3''-hydroxypravastatin, which has been shown to be a natural product with high purity. The metabolite of (S)-3''-hydroxypravastatin sodium salt is 3'-hydroxypravastatin. This product can be used for analytical purposes as well as in pharmacopoeia, drug development, and research and development. It can also be used as an impurity standard for HPLC and GC analysis.</p>

<p>3-(Methylamino)-5,6-dihydro-2H-1,4-thiazin-2-one oxime hydrochloride is an analytical reagent used for HPLC analysis of the impurities in pharmaceutical products. It is a white crystalline solid with a melting point of 235°C. 3-(Methylamino)-5,6-dihydro-2H-1,4-thiazin-2-one oxime hydrochloride is used as a reference standard and has been assigned CAS No. 112233-23-5 by the Chemical Abstracts Service (CAS). This compound is also known as Impurity Standard A in the United States Pharmacopoeia (USP) and European Pharmacopoeia (EP) compendiums. 3-(Methylamino)-5,6-dihydro-2H-1,4-thiazin-2-one oxime</p>