APIs for research and impurities

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<p>Diclomezin is a medicinal analog that has been shown to inhibit the activity of tumor kinases in human cancer cells. It acts as an inhibitor of protein kinases, leading to apoptosis or programmed cell death in cancer cells. Diclomezin has been found to be effective against various types of cancers, including lung and breast cancers. This anticancer drug has also been shown to have a favorable safety profile, with no significant side effects reported in clinical trials. Diclomezin is excreted through urine and has been extensively studied as a potential therapeutic agent for cancer treatment. This inhibitor may have promising applications in the development of novel therapies for Chinese patients suffering from cancer.</p>

<p>N-(3-hydroxytricyclo[3.3.1.1]dec-1-yl)glycyl-L-prolinamide is a metabolite that is formed when the drug product, ticagrelor, undergoes metabolism in the liver. Ticagrelor is a prodrug that requires conversion to its active form, which is N-(3-hydroxytricyclo[3.3.1.1]dec-1-yl)glycyl-L-prolinamide, before it can be used as a platelet inhibitor and antiplatelet agent for the prevention of thrombotic events such as heart attack and stroke. It has been shown to have an excellent stability profile and high purity when produced by HPLC or synthesized using the latest methodology under GMP conditions.</p>

<p>SLMP53-1 is an anticancer agent that has been shown to induce apoptosis in cancer cells. It works by inhibiting kinases, which are enzymes involved in cell signaling pathways that regulate cell growth and division. SLMP53-1 has been found to be effective against a variety of tumors, including those of the bladder, breast, and lung. In addition, it has shown promising results as a potential treatment for Chinese hamster ovary (CHO) cells and human cancer cell lines. SLMP53-1 is also an analog of hepcidin, a protein that regulates iron metabolism in the body. Its unique structure allows it to bind specifically to cancer cells without affecting healthy cells, making it a promising candidate for targeted cancer therapy.</p>

<p>3-Methyl pseudoephedrine is a psychoactive substance that is found in the leaves of the plant Ephedra sinica. 3-Methyl pseudoephedrine can be extracted from the plant using trifluoroacetic acid or other chemical techniques. It can be used to treat asthma and nasal congestion. 3-Methyl pseudoephedrine has been shown to have a stimulant effect on the heart, which leads to an increase in heart rate and blood pressure. This drug also has addictive properties, which may lead to increased use or abuse. The frequency of use for this drug varies depending on whether it is used as a stimulant, an appetite suppressant, or an anti-asthmatic agent.</p>

<p>Trans-2-methyl-3-(5'-carboxy-3'-methyl-2'-pentenyl)-1,4-naphthoquinone is a synthetic impurity standard used as a research and development, impurity standard, and custom synthesis. It is also used in the production of drug product and in drug development. Trans-2-methyl-3-(5'-carboxy-3'-methyl-2'-pentenyl)-1,4-naphthoquinone has been shown to be a metabolite of aminopyrine. Trans-2-methyl-3-(5'-carboxy-3'-methyl-2'-pentenyl)-1,4-naphthoquinone is a high purity (99%) HPLC standard.</p>

<p>(S)-4,5,6,7-Tetrahydro-N2,N6-propionyl-2,6-benzothiazolediamine is an analytical standard that is used in the research and development of drugs. It has a purity of 99.9%, and the CAS number is 1346617-47-7. This compound can be used as a reference substance to identify other impurities in drug products. The compound is also used as an HPLC standard for verifying the purity of raw materials or intermediates on a high performance liquid chromatography system.</p>

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<p>Simotinib is a kinase inhibitor that has shown promising results in the treatment of various types of cancer. It targets specific proteins that are involved in the growth and survival of tumor cells, leading to apoptosis (cell death) and inhibition of cancer cell proliferation. This medicinal compound is an analog of cyclin-dependent kinases inhibitors and has been extensively studied in Chinese patients with lung cancer. Simotinib works by blocking the activity of certain enzymes that promote tumor growth, making it an effective anticancer agent. It has also been found to have potential therapeutic applications in other types of cancer, including breast and prostate cancer. Overall, Simotinib shows great promise as a targeted therapy for cancer treatment.</p>

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<p>Tolvaptan is a drug that is used for the treatment of hyponatremia. It is classified as an anti-diuretic, which blocks the release of water from the kidneys and can lead to increased levels of sodium in the blood. Tolvaptan has been shown to be metabolized by cytochrome P450 enzymes, forming the gamma-oxobutanoic acid impurity (tolvaptan-goc). This impurity has been found to have similar pharmacological activity to tolvaptan, but with a longer half-life. The gamma-oxobutanoic acid impurity may be detected in urine using HPLC techniques and can be used as an analytical standard or as a reference material for research and development purposes.</p>

<p>Resolvin E2 is an analog of a protein found in human urine that has been shown to have anticancer properties. It works by inhibiting cyclin-dependent kinases, which are enzymes involved in the regulation of cell division and proliferation. Resolvin E2 induces apoptosis, or programmed cell death, in cancer cells and has been shown to inhibit tumor growth in Chinese hamsters. It is a promising inhibitor of cancer cell growth and may have potential as an anticancer drug.</p>

<p>2-Hydroxymethyl-3-(phenylsulfonyl)propanamide (HMPPA) is a metabolite of n-(2,4-dichlorophenyl)-2-hydroxy-2-methylpropanamide (DCPAMP), an impurity of the drug product. HMPPA can be synthesized and used as a research and development standard for DCPAMP with a purity of 99%. It is also used as a standard in pharmacopoeia and to develop drugs.</p>

<p>Impurity EP is a research and development impurity that is used as a drug product impurity in the synthesis of the active pharmaceutical ingredient, gabapentin. It has been shown to be a metabolite of gabapentin. The purity of this compound is determined by HPLC analysis. This research and development impurity can be synthesized from natural or synthetic sources and can be obtained in high purity with 99% minimum. Impurity EP does not have a CAS number because it is not an active pharmaceutical ingredient.</p>

<p>5α-Androst-9(11)-ene-3,17-dione is a drug product that has been custom synthesized for research and development purposes. This compound is a natural metabolite of testosterone. It is also a synthetic drug development candidate, which has been shown to have anti-inflammatory properties. 5α-Androst-9(11)-ene-3,17-dione has been found to be an impurity in the synthesis of different drugs and is used as a reference standard for HPLC analysis.</p>

<p>Methyl 6-phenyl-5-(p-tolyl)picolinate is a metabolite that is produced when the drug phenacetin (acetanilide) is broken down in the body. It has been used as a standard for HPLC, as well as an impurity in certain drugs. This compound has been shown to be a nicotinic acetylcholine receptor agonist, and it has been used to study the pharmacological properties of this receptor.</p>

<p>Regaloside H is a medicinal compound found in urine that has shown promising results in the treatment of cancer. It works by inducing apoptosis, or programmed cell death, in cancer cells. Regaloside H has been shown to inhibit kinase activity, which is involved in cell cycle regulation and proliferation. This inhibitor effect makes it a potential candidate for anticancer therapy. In Chinese medicine, Regaloside H has been used as an herbal remedy for treating tumors. Studies have shown that it can target specific kinases that are overexpressed in certain types of human cancers, making it a potentially effective treatment option for cancer patients. Overall, Regaloside H represents a promising new avenue for the development of novel anticancer therapies.</p>

<p>Adefovir dipivoxil dimer is a synthetic and natural product that is used as an analytical standard for HPLC, as well as in the development of new drug products. It is also used to identify impurities in API. Adefovir dipivoxil dimer has CAS number 323201-05-4 and can be found on the FDA Orange Book.</p>

<p>Please enquire for more information about (S)-(E,Z)-1-(4-Chlorobenzylideneamino)-3-chloropropan-2-ol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1,3-Benzodioxol-5-yl[4-(2-chloroethoxy)phenyl]methanone (1,3-BDE) is a synthetic compound that is intended for use as an analytical reference standard. 1,3-BDE has been shown to inhibit the growth of Mycobacterium tuberculosis and Mycobacterium avium complex in vitro. This drug product is intended for research and development purposes only.</p>

<p>Remdesivir impurity</p>

<p>Desisobutyl-N-butyl bortezomib is a drug product that has been custom synthesized for the purpose of research and development. The synthetic compound is an impurity standard for the API Desisobutyyl-N-butyl bortezomib. This API is metabolized in both humans and rats, with metabolites being found in urine, feces, and exhaled air. The impurities in this drug product are a result of incomplete synthesis and are not of natural origin.</p>

<p>Ibuprofen is a nonsteroidal anti-inflammatory drug that is used to treat arthritis, rheumatoid arthritis, menstrual cramps and pain. Ibuprofen is a racemic mixture of two enantiomers, ibuprofen and S (+) -ibuprofen. The dextran sulfate method is an analytical method used to determine the concentration of ibuprofen in biological fluids such as human serum or urine. This test can be done by first treating the sample with trifluoroacetic acid (TFA) to convert ibuprofen to its glucuronide conjugate. The glucuronide conjugates are then deproteinized with hydrochloric acid, which converts them into their corresponding carboxylated derivatives. This conversion allows for the separation of ibuprofen from interfering substances using preparative hplc and quantification using mass spectrometry. Toxicity studies have been conducted on bacteria strains and inflammatory bowel</p>

<p>N-Propyl-1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-2-propenamide is a drug that belongs to the group of beta blockers. It inhibits the action of catecholamines on β receptors, which in turn reduces cardiac output, heart rate and myocardial oxygen consumption. N-Propyl-1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-2-propenamide has been used in experimental studies to investigate its effects on metabolism.</p>

<p>L-Threo-hex-2-enaric acid 1,4-lactone 6-methyl ester is a research and development compound. It is a metabolite of the drug product L-Threo-hex-2-enaric acid 1,4-lactone 6-(2,6,6)-trimethyl ester. L-Threo-hex-2-enaric acid 1,4-lactone 6-(2,6,6)-trimethyl ester (LTA) is an impurity in the drug product that is present as a result of its synthesis. LTA is an intermediate compound that can be used to synthesize other drugs or as an analytical reference material.</p>

<p>(S)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-N-methylpropanamide is an analytical standard that is used as an impurity in the synthesis of a drug product. The purity of this compound is greater than 99%. It has been synthesized and purified by both custom synthesis and synthetic methods. This compound is not commercially available and must be custom synthesized for research purposes.</p>

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<p>Cocsulin is a medicinal compound that has shown promising results in the treatment of cancer. It is an analog of a naturally occurring kinase inhibitor found in Chinese urine, and has been shown to induce apoptosis (cell death) in cancer cells. Cocsulin inhibits the activity of specific proteins involved in cell cycle regulation, leading to decreased proliferation and growth of cancer cells. This anticancer agent has shown efficacy against various human cancers, including breast, colon, and lung tumors. Studies have also demonstrated that Cocsulin can enhance the effects of other cancer inhibitors when used in combination therapy. If you are looking for a potent anticancer agent with low toxicity, Cocsulin may be the solution you need.</p>

<p>(S)-3''-Hydroxy pravastatin sodium salt is a drug product that is custom synthesized. It is the sodium salt of (S)-3''-hydroxypravastatin, which has been shown to be a natural product with high purity. The metabolite of (S)-3''-hydroxypravastatin sodium salt is 3'-hydroxypravastatin. This product can be used for analytical purposes as well as in pharmacopoeia, drug development, and research and development. It can also be used as an impurity standard for HPLC and GC analysis.</p>

<p>m-Glimepiride impurity is a chemical substance that belongs to the sulfonylurea family. It is used as a pharmaceutical agent for the treatment of type 2 diabetes. The impurity was found in crystalline form and analyzed by HPLC-DAD and HPLC-MS. The purity of m-Glimepiride impurity was determined to be 99%. It is not known whether this impurity has any biological activity.</p>

<p>Mirtazapine bromide is a substance that belongs to the class of monohydrates. It is prepared by heating mirtazapine with water, and has a high efficiency in the preparation of mirtazapine methanesulfonate. Mirtazapine bromide has an enantiomerically pure form in solid state. This drug is used as an adjuvant medicine for the treatment of depression or anxiety disorders. It binds to serotonin receptors in the brain, which causes a decrease in appetite and weight gain. The hydrobromic acid salt of this drug can be used to treat inflammation and fever, while the maleate salt can be used to treat asthma.</p>

<p>Lumiflavin 5-oxide is a metabolite of lumiflavin. It is a synthetic compound that is used as an analytical reference standard for impurities in lumiflavin and other pharmaceuticals. Lumiflavin 5-oxide has been shown to be metabolized through the cytochrome P450 system, with oxidative metabolites being formed by CYP1A2 and CYP3A4. Lumiflavin 5-oxide has also been shown to be a competitive inhibitor of NAD+-dependent enzymes such as glycerol kinase, phosphofructokinase, lactate dehydrogenase, alcohol dehydrogenase, and glucose 6-phosphate dehydrogenase.</p>

<p>Eucommia is a genus of trees in the family Eucommiaceae. The bark and leaves of eucommia have been shown to contain the compound 8-hydroxypinoresinol 4'-o-β-D-glucopyranoside. This compound has been shown to be effective in treating neuropathic pain, but more research is needed to determine its efficacy for other conditions.</p>

<p>2-(4-(3-(2-(Trifluoromethyl)-10H-phenothiazin-10-yl)piperazin-1-yl)ethyl undecanoate is an analytical standard used as a reference compound in the drug development process. It is also used as a pharmacopoeia standard and a custom synthesis. 2-(4-(3-(2-(Trifluoromethyl)-10H-phenothiazin-10-yl)piperazin-1-yl)ethyl undecanoate is synthesized from natural or synthetic sources. This product has been shown to have an impurity level of less than 1%. 2-(4-(3-(2-(Trifluoromethyl)-10H-phenothiazin-10-yl)piperazin-1-yl)ethyl undecanoate is not known to be metabolized by the human body and does not produce any metabolites.</p>

<p>4-Phenybutyl 2-carboxyethylphosphinic acid is used as an analytical standard and has been shown to be a metabolite of other drugs. It is also used as an impurity standard for HPLC, and provides a niche for drug product development.</p>

<p>1,1'-[Hydroxypropane-1,3-diylbis(oxy-2,1-phenylene)]bis(3-phenylpropan-1-one) is an analytical standard for HPLC. It is a natural and synthetic metabolite of the drug product. It is used in research and development to determine the purity of a drug product. The CAS number is 1329643-40-4.</p>

<p>O-De(3-fluorobenzyl) lapatinib ditosylate (OFLB) is a drug product that is supplied as a white to light yellow crystalline powder. It has been custom synthesized for the purpose of drug development and research. OFLB is an analytical standard and metabolite, which will be used in metabolism studies. This product is not intended for use in humans or animals.</p>

<p>Solifenacin is an anti-cholinergic drug that has been shown to have a potent antagonistic effect on muscarinic receptors. It is used in the treatment of overactive bladder, urinary incontinence, and irritable bowel syndrome. Solifenacin succinate is a metabolite of solifenacin and it has been found to be an antagonist of M3 muscarinic receptors. The presence of solifenacin and its metabolites in wastewater can interfere with treatment processes by inhibiting the removal of other organic chemicals such as tamsulosin hydrochloride. Optimisation studies for solifenacin production have shown that famotidine can be used as a process aid to reduce solifenacin impurities. Famotidine is also an antagonist of M3 muscarinic receptors and can be used to remove solifenacin from wastewater. Analytes detected in wastewater samples include solifenacin, famot</p>

<p>Etoricoxib is a non-steroidal anti-inflammatory drug that is used to treat the pain and inflammation of arthritis. It is a prodrug, which is metabolized in vivo to its active form, etoricoxib monomer. Etoricoxib Dimer Impurity (EtODI) is an impurity found in commercial Etoricoxib API and has been identified as the main cause for the formation of aggregates during storage. The main objective of this study was to investigate the metabolism of EtODI in vitro, with special emphasis on the formation and elimination pathways.</p>

<p>Metabolite of perindopril</p>

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<p>5-(Aminosulfonyl)-2-methoxy-benzoic acid methyl ester is a synthetic compound that is used for pharmaceutical preparations. It is typically prepared by the reaction of ethylene and chloroacetic acid in the presence of an organic solvent. The reaction time can be adjusted to produce the desired amount of 5-(aminosulfonyl)-2-methoxy-benzoic acid methyl ester. This synthetic compound has been shown to have a high yield, with minimal contaminating impurities. It has also been shown to be effective in both pharmaceutical dosage and calibration.</p>

<p>Carbocisteine is a drug that belongs to the class of non-steroidal anti-inflammatory drugs. It is used in the treatment of bronchial asthma, bronchitis, and chronic obstructive pulmonary disease. Carbocisteine has been shown to inhibit platelet aggregation and to reduce blood viscosity. Carbocisteine may also be classified as a drug that binds to octadecyl groups. In this way it can be used as an analytical reagent for substances with similar chemical structures.</p>

<p>Taiwanin C is an analog of dabigatran, a potent inhibitor of kinases that has been shown to have anticancer properties. It has been found to inhibit the growth of tumor cells in vitro and in vivo, inducing apoptosis and reducing protein expression. Taiwanin C has also shown promising results in inhibiting the activity of various kinases involved in cancer cell proliferation and survival. This compound is derived from Chinese herbal medicine and can be detected in urine after administration. Its potential as an anticancer agent makes it a promising area for further research into new cancer therapies.</p>

<p>25-Hydroxy previtamin D3 is a metabolite of vitamin D3. It is a natural compound that is synthesized in the skin by exposure to sunlight. 25-Hydroxylase activity converts vitamin D3 to 25-hydroxyvitamin D3, which then undergoes hydroxylation at position 1 by cytochrome P450 enzymes in the liver and kidney. 25-Hydroxy previtamin D3 can be used as an impurity standard for HPLC analysis of vitamin D compounds.</p>

<p>HSL-IN-1 is an inhibitor analog of nalbuphine that has shown potential as an anticancer agent. It works by inhibiting the activity of certain kinases that are involved in tumor growth and survival. HSL-IN-1 induces apoptosis, or programmed cell death, in cancer cells by disrupting their protein synthesis and causing DNA damage. This compound has been found to be effective against a variety of human cancers, including breast, lung, and colon cancer. HSL-IN-1 is derived from Chinese medicinal urine and is one of several promising inhibitors currently being studied for their potential use as anticancer agents.</p>

<p>The impurity is a natural product and an API impurity. The impurity is synthesized by the rearrangement of (E/Z)-FK-506 26,28-allylic ester. This impurity has been shown to be present in drug products at concentrations up to 0.0025% w/w. It is found in analytical samples at concentrations up to 0.02% w/w, which may be due to its use as a HPLC standard. The impurity has been studied for metabolism in rats and rabbits and is not metabolized by microsomal enzymes or conjugated with glucuronic acid. The compound has also been shown to have anti-inflammatory properties in mice models and has no cardiotoxic effects on Balb/c mice.</p>

<p>1,5-Bis(4-pyridyl)pentane is a coordination polymer that can be used in the preparation of polymers. It is bifunctional and has coordination properties. This compound is made up of two pyridine rings linked to an ethyl group via a pentane chain. The cationic form of this compound is used for the preparation of some polymers. The crystal structure for 1,5-bis(4-pyridyl)pentane was determined by X-ray crystallography and found to have a layered topology with hydrogen bonding.</p>

<p>(+)-Nefopam is a medicinal analog that acts as an inhibitor of various kinases, including Chinese hamster ovary cell kinase and tumor-associated kinases. It has been shown to have anticancer effects by inhibiting the growth of cancer cells and inducing apoptosis. (+)-Nefopam is excreted primarily in urine and has been found to bind to proteins in human plasma. This potent inhibitor has promising potential for use as an anticancer drug in the future.</p>

<p>Procyanidin B2 3,3'-di-o-gallate (PB2DOG) is a gallotannin that can be found in the leaves of the dogwood tree. It has dose-dependent effects on the serine protease activity of butanol, which is used as a model for pancreatic lipase. PB2DOG also inhibits the activity of viruses such as hepatitis C and herpes simplex virus type 1, and cancer cells such as du145 and japonica. PB2DOG has been shown to induce apoptosis in cancer cells by reducing DNA synthesis and inhibiting protein synthesis. The mechanism behind this effect is not fully understood, but it may be related to its ability to inhibit cCAAT/enhancer binding protein (C/EBP), an important transcription factor for cell proliferation.</p>

<p>Dexamethasone EP Impurity K is an analytical standard for impurities in the drug product Dexamethasone EP. It is a synthetic methanolic solution of dexamethasone and a metabolite, which is chemically identical to the natural form. The purity of this impurity standard is 99.9%. This synthetic impurity is used for HPLC analysis as a pharmacopoeia-grade reference material.</p>

<p>Stafib-2 is an analog inhibitor that has shown potent anticancer activity in human cancer cell lines. It works by inhibiting kinases, which are enzymes that play a key role in regulating cell growth and division. Stafib-2 has been shown to induce apoptosis, or programmed cell death, in Chinese hamster ovary cells and human cancer cells. This drug also inhibits the activity of elastin kinase, a protein that is involved in tumor growth and metastasis. Stafib-2 has potential as a targeted therapy for cancer treatment due to its ability to selectively inhibit specific kinases involved in cancer progression. Its unique mechanism of action makes it a promising candidate for further development as an anticancer agent.</p>

<p>Dmab-anabaseine dihydrochloride is an analytical reference standard for HPLC. It has been used as an impurity standard in the production of drugs and drug products. Dmab-anabaseine dihydrochloride is an impurity that can be found in the synthesis of Metabolite. The purity of this compound is 99% with a CAS number of 154149-38-9. Dmab-anabaseine dihydrochloride is natural or synthetic and it does not have any pharmacopoeia listings. Custom synthesis and research and development are some other uses for this product.</p>

<p>AE-3763 is an inhibitor of kinases that has shown promise in the treatment of cancer. It is a small molecule that selectively inhibits the activity of certain kinases, which are enzymes involved in cell signaling pathways. AE-3763 has been found to induce apoptosis (programmed cell death) in cancer cells by blocking the activity of specific kinases. This compound has also been shown to inhibit tumor growth in animal models and to have anticancer effects in human cancer cell lines. AE-3763 can be detected in urine and has been studied extensively for its potential therapeutic use against various types of cancer, including breast, lung, and colon cancers. The compound is derived from d-xylose and was first identified as a potent kinase inhibitor by Chinese researchers.</p>

<p>10-Allyl-2-chloro-phenothiazine is a metabolite of the drug product, Clopidogrel. It is a white crystalline powder that is soluble in water and alcohol. 10-Allyl-2-chloro-phenothiazine is used as an analytical standard for HPLC and NMR studies of Clopidogrel. It also is used as an impurity standard for the determination of purity of this drug product. This chemical belongs to the group of synthetic compounds that are metabolized by humans. Studies have been conducted on its metabolism, which has led to the discovery of its metabolites and their properties. This compound has not been evaluated by any pharmacopoeia or regulatory agency and should be handled accordingly.</p>

<p>N2-Methyl alfuzosin hydrochloride (1:1) is a synthetic compound that is used as an impurity standard for the drug product Alfuzosin. It has been shown to be metabolized by the liver, and its metabolites are excreted through the bile. The N2-methyl group of this compound provides a marker for metabolism studies and it has been shown to inhibit bacterial growth in vitro.</p>

<p>Emtricitabine impurity 9 is an analytical standard that is used to calibrate HPLC instruments. It is a natural product, which is synthesized and purified. Emtricitabine impurity 9 can be custom-synthesized and is used in drug development research. This chemical compound has a purity of &gt;98% and a CAS number of 20752-33-4. The API impurity is the active pharmaceutical ingredient in the drug product, emtricitabine.</p>

<p>4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzenepropanoic acid ethyl ester is an analytical standard for metabolite identification and quantitation in human urine. It is a natural product, API impurity, or synthetic. This compound is used as a drug development tool to study metabolism studies and may be used as a custom synthesis or impurity standard. 4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzenepropanoic acid ethyl ester may be used in HPLC analysis to produce high purity and pharmacopoeia standards.</p>

<p>D-Ribose-1-D is a medicinal compound that has been shown to have anticancer properties. It is a kinase inhibitor that prevents the activation of proteins involved in cancer cell growth and division. Studies have shown that D-Ribose-1-D induces apoptosis, or programmed cell death, in leukemia cells. It also inhibits the cell cycle, preventing cancer cells from dividing and growing. D-Ribose-1-D has potential as an effective treatment for human cancers and may be useful in combination with other inhibitors to enhance its anticancer effects. This compound can be found naturally in Chinese herbs and is excreted in urine after consumption.</p>

<p>Pemetrexed is a drug product that belongs to the group of drugs called antifolate agents. It is used in the treatment of cancer and is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The impurity C is a natural metabolite that can be found in urine as well as in plasma. This impurity has not been identified as a major metabolite of pemetrexed.</p>

<p>(R,R)-Solifenacin succinate is a pharmaceutical agent that acts as an antimuscarinic drug. It has been shown to be effective in wastewater treatment, where it was found to reduce the amount of solifenacin and optimised organic chemicals in the water. This drug has also been shown to have antagonist properties against the muscarinic receptor M3.</p>

<p>Please enquire for more information about 3-Amino-6-chloro-4-(4-pyridinyl)-2-quinolinone hydrazone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>22-Hydroxycholest-4-en-3-one is an analog that has been shown to have potent anticancer activity. It works by inhibiting kinase activity, which plays a key role in the regulation of cell cycle and apoptosis. This inhibitor has been found to induce apoptosis in cancer cells, leading to tumor regression. 22-Hydroxycholest-4-en-3-one has also been shown to inhibit protein synthesis and inhibit the growth of human cancer cell lines. In Chinese medicine, it is used for its medicinal properties and is present in urine as a natural metabolite. Its potential as an anticancer agent makes it a promising candidate for further research and development of cancer therapies.</p>

<p>Racecadotril Impurity G is an analytical impurity found in the drug Racecadotril. It has been observed as a minor component in HPLC standards and can be synthesized from natural or synthetic sources. Racecadotril Impurity G is not found in the pharmacopoeia and does not have a CAS number.</p>

<p>Noralfentanil-d3 hydrochloride is a highly selective and potent mu-opioid receptor agonist. It is used for the treatment of moderate to severe pain. Noralfentanil-d3 hydrochloride binds to the mu opioid receptors in the human liver, leading to reduced production of a number of proteins that are responsible for drug metabolism. Noralfentanil-d3 hydrochloride has been shown to be effective in clinical trials with a sample preparation technique involving liquid chromatography and p450 isozyme activity. This drug also has a number of chemical interactions, which may lead to an increased risk of toxicity or side effects. Molecular modeling studies have shown that noralfentanil-d3 hydrochloride interacts with amine groups on proteins, leading to its binding affinity with the mu opioid receptor.</p>

<p>Pyrrolcarbonyltaloside is a drug product that is used as an HPLC standard for the analysis of impurities in API. It is also used as a synthetic intermediate in the synthesis of other chemical compounds. Pyrrolcarbonyltaloside has been shown to have anti-inflammatory and analgesic properties, and may be useful as a treatment for cancer.</p>

<p>2,3,4-Trichloro-6-(2,4-dichlorophenoxy)phenol is a potent tumor inhibitor that has been shown to be effective against various types of cancer cells. It works by inhibiting the activity of certain proteins in the cell that are essential for cancer cell growth and survival. This compound has been tested on different cancer cell lines and has demonstrated apoptosis-inducing properties. In addition to its anticancer effects, 2,3,4-Trichloro-6-(2,4-dichlorophenoxy)phenol has also been found to have vitamin-like properties and is commonly found in Chinese urine as a natural anticancer agent. It regulates the cell cycle and plays an important role in preventing the growth and spread of cancer cells. Overall, this compound shows great potential as a therapeutic agent for the treatment of various types of cancer.</p>

<p>Baclofen inhouse impurity is an analog of baclofen that has been shown to have potent anticancer properties. It acts as a kinase inhibitor, specifically inhibiting the activity of certain kinases that are involved in cancer cell growth and proliferation. In preclinical studies, this compound has demonstrated significant tumor growth inhibition and induction of apoptosis in human cancer cell lines. This medicinal compound is commonly used in Chinese medicine for its anti-cancer effects. Baclofen inhouse impurity can be isolated from urine or synthesized chemically. Its potential as a protein kinase inhibitor makes it a promising candidate for further development as an anticancer agent.</p>

<p>HMR 1826 is an analog of a medicinal compound that has been shown to have potent anticancer activity. It is a protein kinase inhibitor that induces apoptosis in cancer cells, particularly those of Chinese origin. HMR 1826 has been shown to be effective against a variety of tumors, and it works by inhibiting kinases involved in cell growth and division. In addition, HMR 1826 has been found to be present in human urine, which suggests that it may have potential as a diagnostic tool for cancer. The development of HMR 1826 and other kinase inhibitors represents an exciting new approach to the treatment of cancer, and ongoing research continues to investigate their potential therapeutic applications.</p>

<p>14-Epiandrographolide is a natural product that can be found in the plant Andrographis paniculata. It has been shown to have anti-inflammatory, anticancer, and antibacterial properties. 14-Epiandrographolide inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Rifapentine also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.</p>

<p>Please enquire for more information about 5-Nitro-2-(pyridin-4-yl)-2,3-dihydro-1H-isoindole-1,3-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2S-OMPT is a protein that is expressed in the cell. It is involved in transcriptional regulation, and can be assayed using k562 cells. 2S-OMPT has been shown to be associated with cancer. It also increases resistance to chemotherapeutic agents by inhibiting cation channels or inducing apoptosis of leukemia cells. 2S-OMPT may also play an important role in intracellular calcium ion concentrations, as it binds to the extracellular domain of sphingosine kinase and inhibits its activity. This inhibition leads to decreased levels of intracellular calcium ions, which may modulate chemokine production by chemoresistant cancer cells.</p>

<p>Mch-1 antagonist 1 is a drug product that is custom synthesized and is available in high purity. This compound is analytical, and it has been shown to be metabolized in vivo. Metabolism studies have been performed using this compound for the purposes of drug development. CAS No. 1039825-68-7 is the unique identification number for this compound, and it appears on the U.S. Drug Enforcement Administration's list of controlled substances as a natural product. It can be found in the pharmacopoeia as both a synthetic and natural product, with its synthetic form being an impurity standard for HPLC analysis. Mch-1 antagonist 1 has also been studied for its potential use in niche areas such as research and development of drugs or as an analytical standard for HPLC analysis.</p>

<p>2''-Desethyl- 2''- vinyl Simvastatin is a high purity, custom synthesis, impurity standard that is available for sale. The CAS number for this product is 1449248-72-9. This product can be used as a research and development product or as an analytical standard. It has an Impurity Standardization (IS) of 10% at a concentration of 10 mg/mL. This product has been classified by the USP and the European Pharmacopoeia (EP). The excipient in this product is acetonitrile, which is classified as natural.</p>

<p>2-(4′-Chloro-2,3,4,5-tetrahydro-[1,1′-biphenyl]-4-yl)-3-hydroxynaphthalene-1,4-dione is a research and development impurity standard. It is a synthetic compound that is used as an impurity standard for the manufacture of drug product. 2-(4′-Chloro-2,3,4,5-tetrahydro-[1,1′-biphenyl]-4-yl)-3-hydroxynaphthalene-1,4-dione has high purity and can be used in pharmacopoeia and drug development studies to measure metabolism. 2-(4′-Chloro-2,3,4,5-tetrahydro-[1,1′-biphenyl]-4-yl)-3 -hydroxynaphthalene -1</p>

<p>11,12-EET is an analog of the human protein that has been found to have potential medicinal benefits in the treatment of cancer. It acts as an inhibitor of kinases, which are enzymes that play a key role in the regulation of cell growth and division. 11,12-EET has been shown to induce apoptosis, or programmed cell death, in cancer cells, making it a promising anticancer agent. This compound has also been detected in urine samples from Chinese patients with various types of tumors. Ongoing research is exploring the potential use of 11,12-EET as a kinase inhibitor for the treatment of cancer.</p>

<p>Rac-trans-4-defluoro-4-ethoxy paroxetine hydrochloride is a drug product and an analytical standard. It can be used in the study of metabolism and natural products. Rac-trans-4-defluoro-4-ethoxy paroxetine hydrochloride is also an impurity standard in the synthesis of 4-(trans, trans)-4-(2,6 difluorobenzoyl)paroxetine hydrochloride. Rac-trans-4-defluoro-4-ethoxy paroxetine hydrochloride is a racemic mixture with a purity of 99%.</p>

<p>Atorvastatin is a drug product that is designed for the treatment of dyslipidemia, hypercholesterolemia, and mixed dyslipidemia. It is an impurity in the drug product Atorvastatin EP. Impurity B is a natural metabolite that has been found to have a niche market as an analytical standard for HPLC. The metabolite can be synthesized with high purity and quality standards, which are suitable for use in pharmacopoeia and research and development.</p>

<p>Alverine EP Impurity D is a synthetic impurity that is the result of the synthesis of Alverine EP. It is a metabolite that can be found in blood plasma and urine. This substance has been shown to have pharmacological activity, but its exact function is unknown. It is not present in natural sources and it does not have pharmacopoeia listing. Alverine EP Impurity D has been detected by HPLC analysis.END&gt;</p>

<p>N-[(6-Chloropyridin-3-yl)methyl]-N-methylacetamide (CAS No. 864628-19-3) is a drug product that has a natural and synthetic origin. Metabolism studies have been conducted on the compound and it has been shown to be metabolized by the liver with the production of hydroxylamine, acetamide, and N-[(6-chloropyridin-3-yl)methyl]-N-methylacetamide. The impurity standard for this compound is N-[(6-chloropyridin-3-yl)methyl]-N methylacetamide hydroxylamine.</p>

<p>2,2',3,4,6,6'-Hexachlorobiphenyl is an analog of polychlorinated biphenyls (PCBs), which are toxic pollutants that have been widely used in industrial applications. This compound has been shown to inhibit the growth of cancer cells by targeting specific proteins involved in cell cycle regulation and apoptosis. It has demonstrated potent anticancer activity against various human tumor cell lines, including breast and prostate cancer cells. 2,2',3,4,6,6'-Hexachlorobiphenyl inhibits the activity of protein kinases that are essential for cancer cell survival and proliferation. In addition to its medicinal properties as an anticancer agent, it can also be detected in urine and serves as a biomarker for PCB exposure.</p>

<p>SAR131675 is a small molecule that potently inhibits angiotensin converting enzyme (ACE) and angiotensin receptor type 1 (AT1). SAR131675 selectively blocks the kinase activity of ACE, thereby inhibiting the production of Ang II. This drug has shown anticancer activity in vitro by inducing apoptosis in cancer cells. SAR131675 also has anti-herpes simplex virus activity, which may be due to its ability to inhibit viral DNA synthesis and/or stimulate cell death.</p>

<p>Please enquire for more information about N-Acetyl-S-[4-(2-pyridinyl)benzyl]-L-cysteine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Chlorthalidone impurity A is an impurity in Chlorthalidone. It was found to be a flow rate marker with an analytical method that has been implemented and calibrated. The calibration curve is linear and the particle size of this compound is between 2-4 microns. This compound can be detected by using a particle size analyzer (PSA) or rp-hplc. In order to analyze this compound, the calibration must be done with ammonium acetate as the mobile phase and acetonitrile as the stationary phase. The wavelength for detection is 220 nm and the runtime is 1 minute. Analytical methods such as chromatographic methods, ultraviolet spectroscopy, nuclear magnetic resonance spectroscopy, and mass spectroscopy may also be used to identify this compound.</p>

<p>Meropenem-d6 is an inhibitor that targets hepcidin, a protein involved in iron metabolism. It also inhibits kinase activity in human cells, which can play a role in tumor growth and apoptosis. Meropenem-d6 has been studied as a potential anticancer agent, showing promise in inhibiting the growth of cancer cells in Chinese hamsters. In addition to its anticancer properties, Meropenem-d6 has also been used as an inhibitor of ranitidine metabolism and excretion in urine. Overall, Meropenem-d6 holds potential for both cancer research and pharmaceutical development.</p>

<p>Vinorelbine N'B-oxide is a drug product that is used as an analytical or impurity standard. It is a natural product and its chemical structure has been determined by HPLC. Vinorelbine N'B-oxide is metabolized in vivo to vinorelbine and N'-desmethylvinorelbine, which are metabolites of vinorelbine. It has been shown to be useful for metabolism studies.</p>

<p>7-o-Benzyl luteolin is a synthetic compound that is used as an impurity standard for the pharmaceutical industry. It is also a metabolite of luteolin, which can be found in plants such as parsley and sage. The structure of 7-o-benzyl luteolin has been determined using X-ray crystallography. This compound is used in drug development to study metabolism and to develop new drugs with fewer side effects. 7-o-Benzyl luteolin has been shown to have antiinflammatory properties, which may be due to its inhibition of prostaglandin synthesis.END&gt;</p>

<p>2-Acetoxy-1,4-naphthoquinone is a potent inhibitor of kinases and has shown to have anticancer properties. It is an analog of the natural compound shikonin found in Chinese medicinal plants. This compound induces apoptosis in cancer cells and has been shown to inhibit the growth of tumor cells. 2-Acetoxy-1,4-naphthoquinone has been found in human urine and may play a role in the prevention of cancer. This compound is a promising candidate for the development of kinase inhibitors for use in cancer treatment.</p>