Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(115 productos)
- CDK(546 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(227 productos)
- HSP(180 productos)
- Integrin(268 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(274 productos)
- PKC(126 productos)
- PLK(25 productos)
- ROCK(62 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
Mostrar 10 subcategorías más
Se han encontrado 3904 productos de "Ciclo celular / Checkpoint"
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ILK-IN-2
CAS:ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.Fórmula:C30H30F3N5OPureza:99.30%Forma y color:SolidPeso molecular:533.59Ref: TM-T5488
1mg46,00€5mg92,00€10mg122,00€25mg154,00€50mg182,00€100mg266,00€200mg386,00€1mL*10mM (DMSO)130,00€GSK461364
CAS:GSK461364 (GSK461364A)(Ki=2.2 nM) inhibits purified Plk1 .The specificity of GSK461364 for Plk1 is more than 1000-fold over Plk2/3.Fórmula:C27H28F3N5O2SPureza:99% - 99.73%Forma y color:SolidPeso molecular:543.6Ref: TM-T6282
1mg34,00€2mg49,00€5mg71,00€10mg117,00€25mg195,00€50mg354,00€100mg528,00€200mg755,00€500mg1.153,00€UNC10217938A
CAS:UNC10217938A is a 3-deazapteridine analog, has strong oligonucleotide enhancing effects.Fórmula:C26H28N6O2Pureza:98%Forma y color:SolidPeso molecular:456.54RCM-1
CAS:RCM-1 is an inhibitor of FOXM1.Fórmula:C20H12N2OS4Pureza:98.08%Forma y color:SolidPeso molecular:424.58Palmatine chloride
CAS:Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.Fórmula:C21H22ClNO4Pureza:97.9% - 99.47%Forma y color:SolidPeso molecular:387.86TH-263
CAS:TH-263 is inactive toward both LIMK1 and LIMK2 and thus can be used as negative control for TH-257, and is a diaryl sulfonamide derivative.Fórmula:C21H20N2O3SPureza:99.54%Forma y color:SolidPeso molecular:380.46Ref: TM-T19578
2mg34,00€5mg49,00€10mg75,00€25mg137,00€50mg192,00€100mg281,00€200mg419,00€1mL*10mM (DMSO)54,00€AT-9283 HCl
CAS:AT-9283, a multi-targeted kinase inhibitor, is used potentially for the treatment of multiple myeloma.Fórmula:C19H24ClN7O2Forma y color:SolidPeso molecular:417.895-Chloro-2'-deoxyuridine
CAS:5-Chloro-2'-deoxyuridine (5-Chlorodeoxyuridine) is a thymine analog.Fórmula:C9H11ClN2O5Pureza:99.54%Forma y color:SolidPeso molecular:262.65EG1
CAS:EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.Fórmula:C22H18N2O5Pureza:97.48%Forma y color:SolidPeso molecular:390.39Ref: TM-T27246
2mg34,00€5mg54,00€10mg86,00€25mg130,00€50mg187,00€100mg260,00€200mg370,00€1mL*10mM (DMSO)33,00€BAY-1816032
CAS:BAY-1816032 is a benzimidazole budding inhibition relieved homolog protein 1 kinase (BUB1) inhibitor.Cost-effective and quality-assured.Fórmula:C27H24F2N6O4Pureza:98.02% - 99.81%Forma y color:SolidPeso molecular:534.51Ref: TM-T10467
1mg35,00€5mg80,00€10mg119,00€25mg230,00€50mg339,00€100mg485,00€200mg665,00€1mL*10mM (DMSO)95,00€Longdaysin
CAS:Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).Fórmula:C16H16F3N5Pureza:99.97%Forma y color:SolidPeso molecular:335.335-Fluorocytidine
CAS:5-Fluorocytidine with antiviral activityFórmula:C9H12FN3O5Pureza:99.23%Forma y color:White PowderPeso molecular:261.21Adefovir dipivoxil
CAS:Adefovir dipivoxil (GS 0840) is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity againstFórmula:C20H32N5O8PPureza:98% - 99.80%Forma y color:It Has Broad-Spectrum Antiviral ActivityPeso molecular:501.47BTB-1
CAS:BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A.Fórmula:C12H8ClNO4SPureza:99.71%Forma y color:SolidPeso molecular:297.71XMD8-92
CAS:XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).Fórmula:C26H30N6O3Pureza:98.21%Forma y color:SolidPeso molecular:474.55FUBP1-IN-1
CAS:FUBP1-in-1: Potent FUBP1 inhibitor with 11.0 M IC50, disrupts FUBP1-DNA binding.Fórmula:C19H14F3N3O2SPureza:99.7%Forma y color:SolidPeso molecular:405.39Ref: TM-T11332
1mg72,00€5mg160,00€10mg245,00€25mg406,00€50mg572,00€100mg772,00€200mg1.035,00€1mL*10mM (DMSO)144,00€Besifloxacin Hydrochloride
CAS:Besifloxacin Hydrochloride (BOL-303224-A) is a fourth-generation fluoroquinolone antibiotic.Fórmula:C19H21ClFN3O3·HClPureza:99.20%Forma y color:Pale Yellow SolidPeso molecular:430.3Ref: TM-T6406
5mg38,00€10mg57,00€25mg97,00€50mg172,00€100mg319,00€200mg470,00€500mg750,00€1mL*10mM (DMSO)52,00€roxifiban
CAS:Roxifiban, a prodrug of XV459, is an antiplatelet agent with high affinity and specificity for platelet glycoprotein IIb/IIIa complex(GPIIb/IIIa) receptors.
Fórmula:C21H29N5O6Pureza:98%Forma y color:SolidPeso molecular:447.48Eptifibatide acetate (148031-34-9 free base)
CAS:Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.Fórmula:C35H49N11O9S2·xC2H4O2Pureza:99.7% - 99.87%Forma y color:SolidPeso molecular:891.012-Chloropyrazine
CAS:2-Chloropyrazine is used in chemical industry.Fórmula:C4H3ClN2Pureza:98.98% - 99.89%Forma y color:Clear Colorless To Yellowish LiquidPeso molecular:114.53CB-6644
CAS:CB-6644 is a small molecule inhibitor of the ATPase activity of the RUVBL1/2 complex.Cost-effective and quality-assured.Fórmula:C29H34ClFN4O5Pureza:96.33% - 99.85%Forma y color:SolidPeso molecular:573.06Ref: TM-T10693
1mg205,00€5mg416,00€10mg533,00€25mg748,00€50mg973,00€100mg1.260,00€1mL*10mM (DMSO)525,00€VPC-80051 racemate
CAS:VPC-80051 is the first small molecule inhibitor of hnRNP A1 splicing activity by using a computer-aided drug discovery approach.Fórmula:C16H13F2N3OPureza:97.36%Forma y color:SolidPeso molecular:301.29C/EBPα inducer 1
CAS:C/EBPα inducer 1 (4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-) is a potential inducer of myeloid differentiation viaFórmula:C20H12FN3O4Pureza:98.99%Forma y color:SolidPeso molecular:377.33MK-8745
CAS:MK-8745 is a potent and selective Aurora A inhibitor.Fórmula:C20H19ClFN5OSPureza:99.09% - 99.79%Forma y color:SolidPeso molecular:431.91TC-E 5003
CAS:TC-E 5003 (NSC-30176) is a selective inhibitor of PRMT1 with IC50 of 1.5 μM.Fórmula:C16H14Cl2N2O4SPureza:97.01%Forma y color:SolidPeso molecular:401.26Antitumor agent-152
CAS:Organic compound, potential dCK inhibitor, with 2-ethyl-3-methoxyphenyl-1,3-thiazole and pyrimidine units.Fórmula:C17H19N5O2S2Pureza:95.00%Forma y color:SolidPeso molecular:389.5Ref: TM-T50079
1mg85,00€5mg170,00€10mg253,00€25mg414,00€50mg583,00€100mg783,00€200mg1.054,00€1mL*10mM (DMSO)185,00€Myoseverin
CAS:Myoseverin triggers myotube fission into single cells, influencing genes for growth, immunity, matrix remodeling, and stress, aiding healing and regeneration.
Fórmula:C24H28N6O2Pureza:99.25%Forma y color:SolidPeso molecular:432.522-Amino-4-hydroxypyrrolo[2,3- d]pyrimidi
CAS:2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine serves as an intermediate.Fórmula:C6H6N4OPureza:99.21% - 99.42%Forma y color:SolidPeso molecular:150.14Pipobroman
CAS:Pipobroman (Vercyte) is an alkylating anti-cancer drug effective in PV and ET with low toxicity and thrombosis risk.Fórmula:C10H16Br2N2O2Pureza:97.08%Forma y color:SolidPeso molecular:356.059-Ethylguanine
CAS:9-Ethylguanine is a model nucleobase commonly used in the studies of DNA interactions with organometallic complexes.Fórmula:C7H9N5OPureza:98.6%Forma y color:SolidPeso molecular:179.18Spermine tetrahydrochloride
CAS:Spermine tetrahydrochloride, a polyamine in all eukaryotic cells, protects DNA from free radicals.Fórmula:C10H26N4·4HClPureza:99.75% - 99.82%Forma y color:SolidPeso molecular:348.18GJ103 sodium salt
CAS:GJ103 sodium salt, a GJ072 analog, lowers surface tension, viscosity, and pH in aqueous solutions, aiding molecular movement.Fórmula:C16H13N4NaO3SPureza:99.70% - 99.91%Forma y color:SolidPeso molecular:364.36Sovilnesib
CAS:Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.Fórmula:C26H34F2N6O4SPureza:99.57%Forma y color:SolidPeso molecular:564.65Ref: TM-T39994
1mg96,00€5mg235,00€10mg376,00€25mg630,00€50mg898,00€100mg1.216,00€1mL*10mM (DMSO)259,00€Gadodiamide
CAS:Gadodiamide is an MRI contrast agent, used in MR imaging procedures to assist in the visualization of blood vessels.Fórmula:C16H26GdN5O8Pureza:99.86% - 99.93%Forma y color:SolidPeso molecular:573.662,2'-Anhydrouridine
CAS:2,2'-Anhydrouridine (2,2'-Cyclouridine) is a research tool for antiviral and anticancer studies.Fórmula:C9H10N2O5Pureza:98.45%Forma y color:SolidPeso molecular:226.19PRT4165
CAS:PRT4165 (NSC600157) is a potent PRC1-mediated H2A ubiquitylation inhibitor.Fórmula:C15H9NO2Pureza:98.91% - 99.6%Forma y color:SolidPeso molecular:235.24Ref: TM-T3110
5mg43,00€10mg49,00€25mg88,00€50mg112,00€100mg182,00€200mg254,00€500mg427,00€1mL*10mM (DMSO)50,00€KIRA6
CAS:KIRA6 is an effective inhibitor of IRE1α RNase kinase (IC50: 0.6 μM). It can trigger an apoptotic response.
Fórmula:C28H25F3N6OPureza:97.91%Forma y color:SolidPeso molecular:518.53N2-Methylguanosine
CAS:N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA's
Fórmula:C11H15N5O5Pureza:97.77%Forma y color:SolidPeso molecular:297.27Triciribine
CAS:Triciribine (NSC-154020) is a DNA synthesis inhibitor, and it also inhibits Akt and HIV-1/2.Fórmula:C13H16N6O4Pureza:99.01% - 99.87%Forma y color:SolidPeso molecular:320.3Ref: TM-T6065
1mg38,00€2mg49,00€5mg80,00€10mg116,00€25mg207,00€50mg329,00€100mg512,00€200mg727,00€1mL*10mM (DMSO)88,00€Rg3039
CAS:Rg3039 (PF-06687859) is a potent DcpS inhibitor. DcpS is a therapeutic target for spinal muscular atrophy (SMA). RG3039 improves motor function in SMA mice.Fórmula:C21H23Cl2N5OPureza:98.24% - 99.58%Forma y color:SolidPeso molecular:432.35VX-11e
CAS:VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; antitumor agent.Fórmula:C24H20Cl2FN5O2Pureza:98.92% - ≥98%Forma y color:SolidPeso molecular:500.35GSK-923295
CAS:GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).Fórmula:C32H38ClN5O4Pureza:96.22% - 98.02%Forma y color:SolidPeso molecular:592.13Ref: TM-T2039
1mg49,00€5mg97,00€10mg168,00€25mg283,00€50mg432,00€100mg605,00€200mg852,00€1mL*10mM (DMSO)136,00€Voruciclib
CAS:Voruciclib: oral, selective CDK inhibitor (Ki: 0.626-9.1 nM), reduces MCL-1, targets CDK9 in diffuse large B-cell lymphoma.Fórmula:C22H19ClF3NO5Pureza:99.89% - 99.99%Forma y color:SolidPeso molecular:469.84FDI-6
CAS:FDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6 binds to the FOXM1 protein and downregulates FOXM1-activated genes.Fórmula:C19H11F4N3OS2Pureza:98.92% - >99.99%Forma y color:SolidPeso molecular:437.43Ref: TM-T4005
1mg34,00€5mg74,00€10mg114,00€25mg192,00€50mg274,00€100mg408,00€200mg597,00€1mL*10mM (DMSO)84,00€CID-797718
CAS:CID-797718 is a protein kinase D1 (PKD1) inhibitor.Fórmula:C12H11NO3Pureza:98.91% - 99.21%Forma y color:SolidPeso molecular:217.22Ref: TM-T1858
1mg62,00€5mg138,00€10mg200,00€25mg339,00€50mg482,00€100mg665,00€200mg893,00€1mL*10mM (DMSO)152,00€MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Fórmula:C9H7NO4Pureza:98.53%Forma y color:Yellow PowderPeso molecular:193.16URMC-099
CAS:URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.Fórmula:C27H27N5Pureza:99.32% - 99.98%Forma y color:SolidPeso molecular:421.54APY29
CAS:APY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.Fórmula:C17H16N8Pureza:96.51% - 98.46%Forma y color:SolidPeso molecular:332.36Ref: TM-T3654
2mg40,00€5mg62,00€10mg90,00€25mg167,00€50mg285,00€100mg515,00€500mg1.071,00€1mL*10mM (DMSO)67,00€NSAH
CAS:NSAH (2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide) is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-Fórmula:C18H14N2O3Pureza:99.27%Forma y color:SolidPeso molecular:306.32BSJ-03-123
CAS:BSJ-03-123 is a potent, CDK6-selective small-molecule degrader.Fórmula:C47H56N10O11Pureza:97.78% - 99.38%Forma y color:SolidPeso molecular:937.01Ref: TM-T5395
1mg87,00€2mg113,00€5mg177,00€10mg259,00€25mg409,00€50mg560,00€100mg800,00€500mg1.611,00€DHFR-IN-3
CAS:DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) is an active biochemical.Fórmula:C8H7BrN4Pureza:99.521% - 99.65%Forma y color:SolidPeso molecular:239.07NU2058
CAS:NU2058 (O(6)-Cyclohexylmethylguanine) is a guanine-based CDK inhibitor, also inhibits DNA topoisomerase II ATPase activity.Fórmula:C12H17N5OPureza:99.34% - 99.92%Forma y color:SolidPeso molecular:247.3Ref: TM-T3186
10mg42,00€25mg78,00€50mg106,00€100mg160,00€200mg230,00€500mg378,00€1mL*10mM (DMSO)47,00€SNS-314 Mesylate
CAS:SNS-314 Mesylate (SNS-314) is an effective and specific Aurora A/B/C inhibitor. SNS-314 is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2.Fórmula:C18H15ClN6OS2·CH4O3SPureza:99.44% - 99.92%Forma y color:SolidPeso molecular:527.04Favipiravir
CAS:Favipiravir is a potent and selective RNA-dependent RNA polymerase inhibitor for the treatment of influenza virus infections.Cost-effective and quality-assured.Fórmula:C5H4FN3O2Pureza:97.32% - 99.90%Forma y color:SolidPeso molecular:157.1CID755673
CAS:CID755673 inhibits PKD (IC50: 182 nM), with selectivity over PLK1, AKT, CAMKIIα, CAK, PKC.Fórmula:C12H11NO3Pureza:97.68% - 99.84%Forma y color:SolidPeso molecular:217.22Carotegrast methyl HCl
CAS:Carotegrast methyl (AJM300/PTC-100) is an oral α4 integrin blocker reducing inflammation and experimental colitis.Fórmula:C25H20Cl3N3O5Forma y color:SolidPeso molecular:548.801Clevudine
CAS:Clevudine (Levovir) fights HBV, blocks viral DNA synthesis, and has a long half-life reducing relapse risk after treatment.Fórmula:C10H13FN2O5Pureza:99.88% - 99.97%Forma y color:SolidPeso molecular:260.22Aplidine
CAS:Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM).Fórmula:C57H87N7O15Pureza:99.86%Forma y color:SolidPeso molecular:1110.34Ref: TM-T9715
1mg235,00€5mg588,00€10mg787,00€25mg1.216,00€50mg1.568,00€100mg2.527,00€1mL*10mM (DMSO)938,00€MLN8054 sodium
CAS:MLN8054 sodium is an Aurora A inhibitor.Fórmula:C25H14ClF2N4NaO2Forma y color:SolidPeso molecular:498.84Piritrexim isethionate
CAS:Piritrexim isethionate, a fat-soluble DHFR inhibitor, shows efficacy in metastatic urothelial cancer with a 5-day oral regimen.Fórmula:C19H25N5O6SForma y color:SolidPeso molecular:451.49MTOB
CAS:MTOB, a CtBP substrate, inhibits CtBP-linked cancer activity in cells/mice and regulates TCF-4, affecting CSC proliferation.Fórmula:C5H7NaO3SPureza:98.23%Forma y color:SolidPeso molecular:170.16Ganciclovir sodium
CAS:Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.Fórmula:C9H13N5NaO4Pureza:99.93%Forma y color:SolidPeso molecular:278.22ML-7 hydrochloride
CAS:ML-7 hydrochloride (ML-7 HCl) is a cell-permeable, reversible, effective, ATP-competitive, and specific inhibitor of myosin light chain kinase (Ki: 300 nM);Fórmula:C15H18ClIN2O2SPureza:99% - 99.26%Forma y color:White PowderPeso molecular:452.74Ref: TM-T3050
2mg34,00€5mg47,00€10mg71,00€25mg141,00€50mg230,00€100mg334,00€200mg434,00€1mL*10mM (DMSO)52,00€Nemorubicin HCL
CAS:Nemorubicin HCL, a PNU152243A salt, acts on resistant tumors via topoisomerase I inhibition and targets NER pathway upregulated cells.Fórmula:C32H38ClNO13Forma y color:SolidPeso molecular:680.1Bohemine
CAS:Bohemine is a cyclin-dependent kinase inhibitor.Fórmula:C18H24N6OPureza:99.09% - 99.53%Forma y color:SolidPeso molecular:340.42GS-441524 HCl
CAS:GS-441524: Inhibits FIP virus, EC50 at 0.78 μM, precursor to active triphosphate, non-toxic up to 100 μM, works at ≥1 μM, metabolite of Remdesivir.Fórmula:C12H14ClN5O4Forma y color:SolidPeso molecular:327.72CWHM-12
CAS:CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).Fórmula:C26H32BrN5O6Pureza:98.05% - 99.83%Forma y color:SolidPeso molecular:590.47Ref: TM-TQ0250
1mg40,00€2mg52,00€5mg88,00€10mg126,00€25mg221,00€50mg369,00€100mg550,00€1mL*10mM (DMSO)96,00€Fasudil dihydrochloride
CAS:Fasudil dihydrochloride inhibits ROCK1/2, PKA, PKC, PKG, and acts as a Ca²⁺ channel blocker and vasodilator, supporting vascular, cardiovascular, and signaling research.Fórmula:C14H19Cl2N3O2SPureza:99.86%Forma y color:SolidPeso molecular:364.29BS194
CAS:BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.Fórmula:C20H27N5O3Pureza:99.85%Forma y color:SolidPeso molecular:385.461,7-Diaminoheptane
CAS:1,7-Diaminoheptane, an aliphatic amine, is used in peptide synthesis and as a substrate, ligand, or reagent.Fórmula:C7H18N2Pureza:99.97%Forma y color:White To Light Yellow Crystalline ChunksPeso molecular:130.23Preq1-Dihydrochloride
CAS:Preq1-Dihydrochloride, a queuosine pathway intermediate, binds strongly to PreQ1 riboswitch aptamer, suppressing protein expression.Fórmula:C7H11Cl2N5OPureza:99.46%Forma y color:SolidPeso molecular:252.1Cdk5 Substrate acetate
Cdk5, a serine/threonine kinase active in neurons, phosphorylates proteins like histone H1; its synthetic substrate has a Km of 5 µM.Fórmula:C55H103N15O14Pureza:96.21%Forma y color:SolidPeso molecular:1198.5Poloxin
CAS:Poloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).Fórmula:C18H19NO3Pureza:99.19%Forma y color:SolidPeso molecular:297.35M2I-1
CAS:M2I-1 inhibits Mad2 binding to Cdc20, disrupting SAC-related PPI and Mad2 dynamics, blocks Mad2-F-Mbp1 in FP assays.Fórmula:C19H24N4O4SPureza:99.02% - >99.99%Forma y color:SolidPeso molecular:404.48NU6027
CAS:NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 μM/1.3 μM, 0.4 μM and 2.2 μM, enter cells more readily than the 6-Fórmula:C11H17N5O2Pureza:98.36%Forma y color:SolidPeso molecular:251.29ML367
CAS:ML367 inhibits ATAD5 stabilization with low micromolar activity, serving as a probe molecule.Fórmula:C19H12F2N4Pureza:99.39%Forma y color:SolidPeso molecular:334.32GSK-25
CAS:GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K, and a dramatically improved P450 profile.Fórmula:C24H16Cl2F2N6OPureza:98.59%Forma y color:SolidPeso molecular:513.33Ref: TM-T4488
1mg44,00€2mg56,00€5mg87,00€10mg111,00€25mg168,00€50mg258,00€100mg430,00€1mL*10mM (DMSO)89,00€A-674563 2HCl(552325-73-2(fb-2hcl))
A-674563 2HCl is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.Fórmula:C22H24Cl2N4OPureza:94.66%Forma y color:SolidPeso molecular:431.36Ref: TM-T6139L
1mg81,00€5mg131,00€10mg178,00€25mg318,00€50mg479,00€100mg692,00€1mL*10mM (DMSO)161,00€Palbociclib
CAS:Palbociclib is an oral CDK4/6 inhibitor, halts Rb phosphorylation, arrests cell cycle, and curbs tumor growth.Fórmula:C24H29N7O2Pureza:98% - 99.9%Forma y color:SolidPeso molecular:447.53IMP-1088
CAS:IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.Fórmula:C25H29F2N5OPureza:98.48% - 99.52%Forma y color:SolidPeso molecular:453.53Ref: TM-T9350
1mg137,00€2mg178,00€5mg268,00€10mg444,00€25mg790,00€50mg1.063,00€1mL*10mM (DMSO)294,00€BTYNB
CAS:BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1. MDK6620 downregulates β-TrCP1 mRNA and reduces activation of NF-κB.Fórmula:C12H9BrN2OSPureza:≥95%Forma y color:SolidPeso molecular:309.186-Thio-2'-Deoxyguanosine
CAS:6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.Fórmula:C10H13N5O3SPureza:97.52%Forma y color:SolidPeso molecular:283.31SL327
CAS:SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to transport through the blood-brain barrier.Fórmula:C16H12F3N3SPureza:97.98% - >99.99%Forma y color:SolidPeso molecular:335.35GDC-0575
CAS:GDC-0575 (ARRY-575) is a highly-selective oral small-molecule Chk1 inhibitor(IC50 of 1.2 nM).Fórmula:C16H20BrN5OPureza:≥95%Forma y color:SolidPeso molecular:378.27AT9283
CAS:AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).
Fórmula:C19H23N7O2Pureza:99.83% - 99.98%Forma y color:SolidPeso molecular:381.43Tegafur-Uracil
CAS:Tegafur-Uracil, an oral anticancer agent for solid tumor research, inhibits thymidylate synthase.Fórmula:C12H13FN4O5Forma y color:SolidPeso molecular:312.257Levoleucovorin Calcium
CAS:Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.Fórmula:C20H21N7O7·CaPureza:99.07% - ≥98%Forma y color:White Crystalline PowderPeso molecular:511.5Afuresertib
CAS:Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplasticFórmula:C18H17Cl2FN4OSPureza:97.51% - 99.51%Forma y color:SolidPeso molecular:427.32Ref: TM-T1911
1mg37,00€2mg52,00€5mg74,00€10mg92,00€25mg166,00€50mg259,00€100mg452,00€500mg982,00€1mL*10mM (DMSO)74,00€Danofloxacin
CAS:Danofloxacin (Danofloxacin free base) is a fluoroquinolone antibiotic used in veterinary medicine.Fórmula:C19H20FN3O3Pureza:99.77% - 99.8%Forma y color:SolidPeso molecular:357.38CC-671
CAS:CC-671 is a dual TTK protein kinase (IC50: 0.005 μM) /CLK2 (IC50: 0.006 μM) inhibitor.Fórmula:C28H28N6O4Pureza:98.66% - 98.8%Forma y color:SolidPeso molecular:512.56Ref: TM-T4482
1mg50,00€5mg105,00€10mg170,00€25mg340,00€50mg512,00€100mg733,00€500mg1.513,00€1mL*10mM (DMSO)120,00€Calcium N5-methyltetrahydrofolate
CAS:Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease andFórmula:C20H23CaN7O6Pureza:99.41%Forma y color:SolidPeso molecular:497.51AT13148
CAS:AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.Fórmula:C17H16ClN3OPureza:98.04% - ≥95%Forma y color:SolidPeso molecular:313.78Bractoppin
CAS:Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibitsFórmula:C25H23FN4OPureza:98.38%Forma y color:SolidPeso molecular:414.47Ref: TM-T8873
1mg50,00€5mg99,00€10mg158,00€25mg309,00€50mg465,00€100mg697,00€500mg1.404,00€1mL*10mM (DMSO)109,00€FIT-039
CAS:FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).Fórmula:C17H18FN3SPureza:98.61%Forma y color:SolidPeso molecular:315.41Cedazuridine hydrochloride
Cedazuridine (E7727) hydrochloride is an oral cancer research drug blocking cytidine deaminase (IC50=0.4μM).Fórmula:C9H15ClF2N2O5Forma y color:SolidPeso molecular:304.68Rifamycin sodium
CAS:Rifamycin sodium (Rifamycin sodium salt) salt is an antibiotic that inhibits bacterial DNA-dependent RNA polymerase.Fórmula:C37H46NNaO12Pureza:97.72%Forma y color:CoaPeso molecular:719.75IRE1α kinase-IN-1
CAS:IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM.Fórmula:C26H26ClFN8Pureza:99.18%Forma y color:SolidPeso molecular:504.99Ref: TM-T9564
1mg110,00€5mg268,00€10mg427,00€25mg670,00€50mg964,00€100mg1.333,00€1mL*10mM (DMSO)295,00€Benzamidine hydrochloride
CAS:Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin.Fórmula:C7H9ClN2Pureza:99.25% - 99.97%Forma y color:White To Off-White PowderPeso molecular:156.61Emvistegrast
CAS:Emvistegrast is a quinolone derivative that acts as an antagonist for the α4β7 integrin.Fórmula:C35H32F4N6O6Forma y color:SolidPeso molecular:708.66Datelliptium chloride hydrochloride
CAS:Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.
Fórmula:C23H29Cl2N3OPureza:99.46%Forma y color:SolidPeso molecular:434.4
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