Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(115 productos)
- CDK(546 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(227 productos)
- HSP(180 productos)
- Integrin(268 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(274 productos)
- PKC(126 productos)
- PLK(25 productos)
- ROCK(62 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
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Se han encontrado 3904 productos de "Ciclo celular / Checkpoint"
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Favipiravir sodium
CAS:Favipiravir sodium inhibits viral RNA polymerases, effective against flu, West Nile, yellow fever, and more RNA viruses.Fórmula:C5H4FN3NaO2Forma y color:SolidPeso molecular:180.09MLS000532223
CAS:MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).Fórmula:C15H9NO3Pureza:98.6%Forma y color:SolidPeso molecular:251.24Ref: TM-T8473
1mg105,00€5mg250,00€10mg401,00€25mg685,00€50mg982,00€100mg1.341,00€1mL*10mM (DMSO)301,00€Hesperadin
CAS:Hesperadin(IC50=250 nM) effectively inhibits Aurora B.Fórmula:C29H32N4O3SPureza:98.04% - 99.44%Forma y color:SolidPeso molecular:516.65Reversine
CAS:Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).Fórmula:C21H27N7OPureza:98% - 99.45%Forma y color:SolidPeso molecular:393.49Ref: TM-T1825
1mg35,00€2mg50,00€5mg66,00€10mg84,00€25mg156,00€50mg212,00€100mg371,00€1mL*10mM (DMSO)66,00€SB-743921 hydrochloride
CAS:SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).Fórmula:C31H34Cl2N2O3Pureza:95.58% - 99.70%Forma y color:SolidPeso molecular:553.52Ref: TM-T2255
1mg39,00€5mg101,00€10mg155,00€25mg263,00€50mg406,00€100mg622,00€500mg1.423,00€1mL*10mM (DMSO)123,00€BCH001
CAS:BCH001 is a specific small-molecule inhibitor of PAPD5.Fórmula:C20H15F3N2O5Pureza:99.06%Forma y color:SolidPeso molecular:420.34P005091
CAS:P005091 (P5091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 of 4.2 μM.Fórmula:C12H7Cl2NO3S2Pureza:99.53% - 99.87%Forma y color:SolidPeso molecular:348.22USP7-IN-8
CAS:Benzamide, 4-[6-amino-4-ethyl-5-(4-hydroxyphenyl)-3-pyridinyl]-N-methyl- is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM.Fórmula:C21H21N3O2Pureza:99.31%Forma y color:SolidPeso molecular:347.41Ref: TM-T9217
1mg46,00€5mg92,00€10mg147,00€25mg269,00€50mg389,00€100mg532,00€200mg705,00€1mL*10mM (DMSO)100,00€XL177A
CAS:XL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34 nM). XL177A elicits cancer cell killing through a p53-dependent mechanism.Fórmula:C48H57ClN8O5Pureza:98.75%Forma y color:SolidPeso molecular:861.47BDP5290
CAS:BDP5290 is a potent inhibitor of both ROCK and MRCK(IC50s of 5 nM, 50 nM, 10 nM and 100 nM for ROCK1, ROCK2, MRCKα and MRCKβ, respectively.)Fórmula:C17H18ClN7OPureza:97.22%Forma y color:SolidPeso molecular:371.82Ref: TM-T7301
1mg52,00€2mg77,00€5mg113,00€10mg178,00€25mg369,00€50mg535,00€100mg780,00€1mL*10mM (DMSO)124,00€SAR407899 hydrochloride
CAS:SAR407899 hydrochloride is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human andFórmula:C14H17ClN2O2Pureza:99.15%Forma y color:SolidPeso molecular:280.75KenPaullone
CAS:KenPaullone (9-Bromopaullone), a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell differentiation.Fórmula:C16H11BrN2OPureza:97.14% - 98.99%Forma y color:Tan SolidPeso molecular:327.18Ref: TM-T2247
1mg35,00€2mg50,00€5mg66,00€10mg89,00€25mg178,00€50mg303,00€100mg449,00€500mg1.018,00€1mL*10mM (DMSO)71,00€GNE-6640
CAS:GNE-6640: non-covalent USP7 inhibitor; IC50s: 0.75 µM (full), 0.43 µM (catalytic), 20.3 µM (USP43), 0.23 µM (Ub-MDM2).Fórmula:C20H18N4OPureza:98.64%Forma y color:SolidPeso molecular:330.38Ref: TM-T5461
1mg66,00€2mg96,00€5mg144,00€10mg236,00€25mg507,00€50mg730,00€100mg1.018,00€1mL*10mM (DMSO)158,00€R-IMPP
CAS:R-IMPP is an inhibitor of PCSK9 translation.Fórmula:C24H27N3O2Pureza:99.47% - 99.85%Forma y color:SolidPeso molecular:389.49Ref: TM-T4058
1mg46,00€2mg56,00€5mg88,00€10mg140,00€25mg280,00€50mg500,00€100mg718,00€1mL*10mM (DMSO)75,00€MLCK inhibitor peptide 18 acetate
MLCK inhibitor peptide 18 acetate: Selective (IC50=50nM), 4000x more than CaM kinase II. Does not block PKA. Cell-permeable.Fórmula:C62H109N23O13Pureza:99.57%Forma y color:SolidPeso molecular:1384.67ROCK-IN-2
CAS:ROCK-IN-2 (Azaindole 1) is a selective and ATP-competitive ROCK inhibitor with IC50 of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2.Fórmula:C18H13ClF2N6OPureza:97.29%Forma y color:SolidPeso molecular:402.79Ref: TM-TQ0110
1mg108,00€5mg260,00€10mg416,00€25mg690,00€50mg964,00€100mg1.305,00€1mL*10mM (DMSO)353,00€EOAI3402143
CAS:EOAI3402143 inhibits Usp9x and Usp24 activity, increases tumor cell apoptosis.Fórmula:C25H28Cl2N4O3Pureza:99.6%Forma y color:SolidPeso molecular:503.42Ref: TM-T11209
1mg63,00€5mg137,00€10mg215,00€25mg423,00€50mg680,00€100mg1.009,00€1mL*10mM (DMSO)152,00€NSC632839
CAS:NSC-632839 (Ubiquitin Isopeptidase Inhibitor II) is a nonselective isopeptidase inhibitor, which inhibits USP2 (EC50: 45±4 μM), USP7 (EC50: 37±1 μM), and SENP2Fórmula:C21H22ClNOPureza:99.74% - 99.88%Forma y color:SolidPeso molecular:339.86Trifluridine/tipiracil hydrochloride mixture
CAS:Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in aFórmula:C29H34Cl2F6N8O12Pureza:98% - 99.79%Forma y color:SolidPeso molecular:871.53Ref: TM-T3658
2mg37,00€5mg54,00€10mg93,00€25mg148,00€50mg236,00€100mg358,00€200mg538,00€500mg842,00€1mL*10mM (DMSO)73,00€LDC4297 hydrochloride
CAS:LDC4297 hydrochloride is a selective and potent CDK7 inhibitor with broad-spectrum antiviral activity, useful for research on viral infections.Fórmula:C23H29ClN8OForma y color:SolidPeso molecular:468.98Arg-Gly-Asp TFA (99896-85-2(free base))
Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.Fórmula:C14H23F3N6O8Pureza:99.2% - ≥98%Forma y color:SolidPeso molecular:460.36Tempo
CAS:Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as aFórmula:C9H18NOPureza:98.35%Forma y color:Orange Crystals Or PowderPeso molecular:156.25Netarsudil mesylate
CAS:Netarsudil mesylate (AR-13324 mesylate) is a Rho-related protein kinase inhibitor used to study glaucoma and hypertension.Fórmula:C30H35N3O9S2Pureza:99.7%Forma y color:SolidPeso molecular:645.74Ref: TM-T10358L2
1mg34,00€5mg66,00€10mg105,00€25mg236,00€50mg409,00€100mg700,00€1mL*10mM (DMSO)96,00€Remdesivir
CAS:Remdesivir (GS-5734) is a nucleoside analog, a broad-spectrum antiviral compound that exerts its activity by inhibiting the RNA-dependent RNA polymerase ofFórmula:C27H35N6O8PPureza:97.62% - 99.98%Forma y color:SolidPeso molecular:602.58Ref: TM-T7766
1mg108,00€5mg205,00€10mg326,00€25mg497,00€50mg663,00€100mg1.063,00€1mL*10mM (DMSO)268,00€SRPIN340
CAS:SRPIN340 (SRPK inhibitor), a serine/arginine-rich protein kinase (SRPK)-specific inhibitor, is potent for SRPK1 (IC50 = 0.89 uM).Fórmula:C18H18F3N3OPureza:99.79% - 99.96%Forma y color:SolidPeso molecular:349.35Ref: TM-T1954
2mg44,00€5mg65,00€10mg100,00€25mg177,00€50mg324,00€100mg421,00€500mg945,00€1mL*10mM (DMSO)71,00€CKI-7
CAS:CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.Fórmula:C11H14Cl3N3O2SPureza:>99.99%Forma y color:SolidPeso molecular:358.67Ref: TM-T19913
1mg73,00€5mg128,00€10mg185,00€25mg299,00€50mg405,00€100mg545,00€1mL*10mM (DMSO)140,00€LDN-192960
CAS:LDN-192960 is a potent inhibitor of Haspin and DYRK2 (IC50s: 10 nM and 48 nM).Fórmula:C18H20N2O2SPureza:99.01% - 99.51%Forma y color:SolidPeso molecular:328.43Ref: TM-TQ0111
1mg49,00€2mg64,00€5mg92,00€10mg152,00€25mg295,00€50mg477,00€100mg763,00€200mg1.018,00€1mL*10mM (DMSO)104,00€L189
CAS:L189 is a human DNA ligase inhibitor, inhibits hLigI/III/IV (IC50: 5/9/5 μM).Fórmula:C11H10N4OSPureza:97.37%Forma y color:SolidPeso molecular:246.29CeMMEC13
CAS:CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).Fórmula:C19H16N2O4Pureza:98.52%Forma y color:SolidPeso molecular:336.34Ref: TM-T6801
1mg34,00€2mg44,00€5mg66,00€10mg105,00€25mg230,00€50mg334,00€100mg447,00€1mL*10mM (DMSO)73,00€Protein kinase inhibitors 1
CAS:Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.Fórmula:C18H17N5O3SPureza:98%Forma y color:SolidPeso molecular:383.42SJB2-043
CAS:SJB2-043 is an inhibitor of USP1-UAF1 ( IC50 : 544 nM).Fórmula:C17H9NO3Pureza:98.44%Forma y color:SolidPeso molecular:275.26Indirubin-3'-monoxime
CAS:Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/Fórmula:C16H11N3O2Pureza:99.55%Forma y color:Dark Red SolidPeso molecular:277.28USP25/28 inhibitor AZ1
CAS:USP25/28 inhibitor AZ1 is a selective, orally active and non-competitive dual ubiquitin-specific protease USP25/28 inhibitor.Cost-effective and quality-assured.Fórmula:C17H16BrF4NO2Pureza:99.79% - 99.86%Forma y color:SolidPeso molecular:422.21Ref: TM-T7685
1mg34,00€5mg66,00€10mg92,00€25mg200,00€50mg304,00€100mg447,00€500mg982,00€1mL*10mM (DMSO)73,00€WR99210
CAS:WR99210 (BRL 6231 free base) is a DHFR inhibitor with antiparasitic activity.Fórmula:C14H18Cl3N5O2Pureza:98.8%Forma y color:SolidPeso molecular:394.68ID-8
CAS:ID-8, a DYRK inhibitor, sustains embryonic stem cell self-renewal in long-term culture.Fórmula:C16H14N2O4Pureza:99.32%Forma y color:SolidPeso molecular:298.29AZ191
CAS:AZ191（IC50 of 17 nM） is an effective and specific DYRK1B inhibitor.Fórmula:C24H27N7OPureza:98.04% - 99.65%Forma y color:SolidPeso molecular:429.52Hexapeptide-10 Acetate
Hexapeptide-10 Acetate (Hexapeptide-10 Acetate) is a synthetic peptide.Fórmula:C30H57N7O10Pureza:98.84%Forma y color:SolidPeso molecular:675.81GNF4877
CAS:GNF4877 inhibits DYRK1A/GSK3β (IC50: 6/16 nM), blocks NFATc export, and boosts β-cell growth.Fórmula:C25H27FN6O4Pureza:98.68% - 99.40%Forma y color:SolidPeso molecular:494.52SAR407899
CAS:SAR407899 is Rho kinase inhibitor potently inhibits endothelin-1-induced constriction of renal resistance arteries.Fórmula:C14H16N2O2Pureza:99.42%Forma y color:SolidPeso molecular:244.29Ref: TM-T7391
2mg34,00€5mg50,00€10mg75,00€25mg128,00€50mg200,00€100mg319,00€200mg474,00€1mL*10mM (DMSO)55,00€USP7/USP47 inhibitor
CAS:USP7/USP47 inhibitor (USP7/47 inhibitor-1) is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 μM and 1.0 μM,Fórmula:C18H11Cl2N3O3S3Pureza:98.5% - 98.71%Forma y color:SolidPeso molecular:484.4Ref: TM-T4338
1mg40,00€5mg96,00€10mg152,00€25mg268,00€50mg429,00€100mg703,00€200mg954,00€1mL*10mM (DMSO)94,00€BSJ-4-116
CAS:BSJ-4-116: potent, selective CDK12 PROTAC, IC50 = 6 nM; downregulates DDR genes, induces premature transcription termination.Fórmula:C40H49ClN8O8SPureza:99.09%Forma y color:SolidPeso molecular:837.38ML364
CAS:ML364 is an inhibitor of ubiquitin specific peptidase 2 (USP2) and can be used for the research of breast cancer.Fórmula:C24H18F3N3O3S2Pureza:99.35% - >99.99%Forma y color:SolidPeso molecular:517.54CID 2011756
CAS:CID 2011756 is an ATP-competitive and specific PKD1 inhibitor.Fórmula:C22H21ClN2O3Pureza:98.15% - ≥95%Forma y color:SolidPeso molecular:396.87GAK inhibitor 49
CAS:GAK inhibitor 49 is a highly selective and ATP-competitive cyclin G associated kinase (GAK) inhibitor (IC50: 56 nM; Ki: 0.54 nM ).Fórmula:C20H22N2O5Pureza:98.71%Forma y color:SolidPeso molecular:370.4Ref: TM-T8535
1mg54,00€5mg111,00€10mg177,00€25mg299,00€50mg430,00€100mg587,00€200mg792,00€1mL*10mM (DMSO)128,00€BI-847325
CAS:BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.Fórmula:C29H28N4O2Pureza:97.13% - 97.54%Forma y color:SolidPeso molecular:464.56GDC0575 monohydrochloride
CAS:GDC0575 (ARRY575), a potent Chk1 inhibitor, IC50 1.2nM, disrupts cell cycle arrest, allowing DNA repair before mitosis.Fórmula:C16H21BrClN5OPureza:97.85%Forma y color:SolidPeso molecular:414.73Ref: TM-T27407
1mg43,00€2mg55,00€5mg80,00€10mg103,00€25mg177,00€50mg255,00€100mg356,00€200mg520,00€1mL*10mM (DMSO)93,00€Aurora kinase inhibitor-2
CAS:Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).Fórmula:C23H20N4O3Pureza:98.66%Forma y color:SolidPeso molecular:400.43Ref: TM-T9040
1mg63,00€5mg138,00€10mg200,00€25mg360,00€50mg532,00€100mg788,00€200mg1.063,00€1mL*10mM (DMSO)150,00€SR18662
SR18662, improved ML264 derivative, inhibits KLF5 at 4.4 nM IC50; curbs colorectal cancer cell growth and triggers apoptosis.Fórmula:C16H19Cl2N3O4SPureza:98.97% - 99.2%Forma y color:SolidPeso molecular:420.31Ref: TM-T22429
1mg46,00€5mg90,00€10mg152,00€25mg295,00€50mg475,00€100mg680,00€200mg888,00€500mg1.378,00€1mL*10mM (DMSO)100,00€BIO-1211
CAS:BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).Fórmula:C36H48N6O9Pureza:99.33%Forma y color:SolidPeso molecular:708.8PKD-IN-1
CAS:CRT0066101 is an inhibitor of PKD.Fórmula:C18H19ClN4OPureza:98%Forma y color:SolidPeso molecular:342.82GNE-6776
CAS:GNE-6776 is a selective USP7 inhibitor.Fórmula:C20H20N4O2Pureza:96.59% - 98.2%Forma y color:SolidPeso molecular:348.4DUB-IN-1
CAS:DUB-IN-1, with an IC50 value of 0.24 for USP8, is an active inhibitor of ubiquitin-specific protease (USPs).Fórmula:C20H11N5OPureza:98.33% - 98.96%Forma y color:SolidPeso molecular:337.33Ref: TM-T11110
1mg62,00€5mg110,00€10mg173,00€25mg334,00€50mg469,00€100mg618,00€200mg848,00€1mL*10mM (DMSO)122,00€α2β1 Integrin Ligand Peptide acetate
α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) is a potential antagonist of α2β1 integrin receptor.Fórmula:C16H26N4O11Pureza:98.46%Forma y color:SolidPeso molecular:450.4Hydroxyfasudil Hydrochloride
CAS:Hydroxyfasudil Hydrochloride (HA 1100 hydrochloride) is a ROCK1/2 inhibitor (IC50s: 0.73/0.72 μM).Fórmula:C14H18ClN3O3SPureza:98.05%Forma y color:SolidPeso molecular:343.83DUB-IN-2
CAS:Dub-in-2, with an IC50 value of 0.28 for USP8, is an effective deubiquitinase inhibitor.Fórmula:C15H9N5OPureza:98.96%Forma y color:SolidPeso molecular:275.26Ref: TM-T11111
1mg54,00€5mg155,00€10mg233,00€25mg467,00€50mg682,00€100mg990,00€1mL*10mM (DMSO)169,00€P18IN011
CAS:P18IN011 (P18IN011 - CAS 77408-67-4 - Calbiochem) is a novel inhibitor of p18(INK4C).
Fórmula:C15H12N2O5SPureza:97.63%Forma y color:SolidPeso molecular:332.33AG-636
CAS:AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.Fórmula:C21H17N3O2Pureza:99.19%Forma y color:SolidPeso molecular:343.38HQ461
CAS:HQ461, a molecular glue, boosts CDK12-DDB1 binding, lowers cyclin K, impedes CDK12 phosphorylation, hinders DNA repair genes, and induces cell death.Fórmula:C15H15N5OS2Pureza:98.11%Forma y color:SolidPeso molecular:345.44Ref: TM-T9849
1mg43,00€2mg56,00€5mg93,00€10mg144,00€25mg319,00€50mg537,00€100mg767,00€500mg1.558,00€1mL*10mM (DMSO)90,00€Hydroxyfasudil
CAS:Hydroxyfasudil (Hydroxy-Fasudil) is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively).Fórmula:C14H17N3O3SPureza:98.13%Forma y color:SolidPeso molecular:307.37ZCL278
CAS:ZCL278 is a selective Cdc42 GTPase inhibitor.Fórmula:C21H19BrClN5O4S2Pureza:96.29% - 99.72%Forma y color:SolidPeso molecular:584.89Ref: TM-T1855
5mg52,00€10mg74,00€25mg129,00€50mg210,00€100mg294,00€200mg470,00€500mg763,00€1mL*10mM (DMSO)74,00€AI-10-49
CAS:AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.Fórmula:C30H22F6N6O5Pureza:97.14%Forma y color:SolidPeso molecular:660.52Ref: TM-T6753
2mg38,00€5mg57,00€10mg92,00€25mg160,00€50mg231,00€100mg343,00€200mg485,00€1mL*10mM (DMSO)84,00€TCID
CAS:TCID (UCH-L3 Inhibitor)(IC50=0.6 μM) is a DUB inhibitor of ubiquitin C-terminal hydrolase L3. It has the 125-fold selectivity to L1.Fórmula:C9H2Cl4O2Pureza:99.34%Forma y color:SolidPeso molecular:283.92Deoxythymidine triphosphate
CAS:Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.Fórmula:C10H17N2O14P3·XNaPureza:99.78%Forma y color:White Amorphous PowderPeso molecular:482.17（free base）NVP-LCQ195
CAS:NVP-LCQ195 (LCQ-195) (AT9311) is a potent inhibitor of CDK1, CDK2, CDK3 and CDK5 (IC50: 1-42 nM).Fórmula:C17H19Cl2N5O4SPureza:99.56% - 99.85%Forma y color:SolidPeso molecular:460.33Ref: TM-TQ0068
1mg46,00€5mg92,00€10mg138,00€25mg255,00€50mg374,00€100mg533,00€200mg705,00€1mL*10mM (DMSO)94,00€RKI-1447
CAS:RKI-1447 is a potent inhibitor of ROCK1 and ROCK2. It has anti-invasive and antitumor activities.Fórmula:C16H14N4O2SPureza:98% - 99.73%Forma y color:SolidPeso molecular:326.37Ref: TM-T1898
5mg49,00€10mg93,00€25mg177,00€50mg295,00€100mg391,00€200mg494,00€500mg797,00€1mL*10mM (DMSO)54,00€P 22077
CAS:P 22077 (P22077) is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM. It also inhibits the closely related USP47.Fórmula:C12H7F2NO3S2Pureza:97.9% - 99.64%Forma y color:SolidPeso molecular:315.32DUB-IN-3
CAS:DUB-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor and the IC50 for USP8 is 0.56 μM.Fórmula:C16H9N5OPureza:99.34%Forma y color:SolidPeso molecular:287.28Ref: TM-T11112
1mg130,00€2mg178,00€5mg309,00€10mg442,00€25mg705,00€50mg982,00€100mg1.333,00€500mg2.655,00€1mL*10mM (DMSO)324,00€THAL-SNS-032
CAS:THAL-SNS-032 is a selective CDK9 degrader PROTAC.Fórmula:C40H52N8O10S2Pureza:99.68%Forma y color:SolidPeso molecular:869.02Ref: TM-T17069
1mg110,00€5mg259,00€10mg389,00€25mg622,00€50mg884,00€100mg1.198,00€1mL*10mM (DMSO)389,00€GRGDSP acetate(91037-75-1 free base)
GRGDSP acetate(91037-75-1 free base) is a synthetic linear RGD peptide and is an integrin inhibitor.Fórmula:C24H41N9O12Pureza:99.77%Forma y color:SolidPeso molecular:647.64Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)
Gly-Arg-Gly-Asp-Ser (GRGDS) acetate is a cell binding protein domain derived from the cell-binding region of fibronectin.Fórmula:C19H34N8O11Pureza:99.81%Forma y color:SolidPeso molecular:550.52VLX1570
CAS:VLX1570 is a competitive inhibitor of proteasome DUB activity with IC50 ranging from 4.2 uM to 8.6 uM. It has potent inhibition for USP14.Fórmula:C23H17F2N3O6Pureza:98.53% - 99.91%Forma y color:SolidPeso molecular:469.39Ref: TM-T4067
1mg90,00€2mg146,00€5mg245,00€10mg385,00€25mg645,00€50mg888,00€100mg1.234,00€1mL*10mM (DMSO)251,00€Thiazovivin
CAS:Thiazovivin, a ROCK inhibitor (IC50: 0.5 μM), increases the survival rate of hESC.Fórmula:C15H13N5OSPureza:98.00%Forma y color:SolidPeso molecular:311.36Ref: TM-T2155
1mg34,00€2mg46,00€5mg64,00€10mg98,00€25mg180,00€50mg304,00€100mg444,00€1mL*10mM (DMSO)70,00€N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamine
CAS:Novel 2,6-naphthyridine inhibits PKC/PKD, identified by HTS.Fórmula:C23H28N6Pureza:98.35%Forma y color:SolidPeso molecular:388.51Indirubin-3′-oxime
CAS:Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.Fórmula:C16H11N3O2Pureza:98.34%Forma y color:SolidPeso molecular:277.28Ref: TM-T9138
1mg44,00€5mg93,00€10mg120,00€25mg236,00€50mg356,00€100mg532,00€200mg772,00€1mL*10mM (DMSO)92,00€LY3177833
CAS:LY3177833 is an Cdc7 kinase inhibitor (IC50 : 3.3 nM)Fórmula:C16H12FN5OPureza:99.87%Forma y color:SolidPeso molecular:309.3Ref: TM-T7810
1mg38,00€5mg80,00€10mg109,00€25mg212,00€50mg318,00€100mg477,00€200mg677,00€1mL*10mM (DMSO)87,00€PHA-767491
CAS:PHA-767491 (CAY10572) is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.Fórmula:C12H11N3OPureza:99.49% - >99.99%Forma y color:SolidPeso molecular:213.24Ref: TM-T6206
2mg34,00€5mg49,00€10mg64,00€25mg92,00€50mg138,00€100mg197,00€200mg295,00€1mL*10mM (DMSO)50,00€CCG-222740
CAS:CCG-222740 is an inhibitor of Rho/MRTF pathwayFórmula:C23H19ClF2N2O3Pureza:98.76%Forma y color:SolidPeso molecular:444.86Ref: TM-T7764
2mg39,00€5mg62,00€10mg94,00€25mg172,00€50mg260,00€100mg371,00€200mg530,00€1mL*10mM (DMSO)66,00€Activated Protein C (390-404), human acetate
Activated Protein C (390-404), human acetate (Activated Protein C ) inhibits APC anticoagulant activity.Fórmula:C93H134N22O25Pureza:99.92%Forma y color:SolidPeso molecular:1960.19Metoprine
CAS:Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.Fórmula:C11H10Cl2N4Pureza:98.42%Forma y color:SolidPeso molecular:269.13Irigenin
CAS:Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the ExtraFórmula:C18H16O8Pureza:99.50% - 99.85%Forma y color:SolidPeso molecular:360.31AT-130
CAS:AT-130: Strong HBV inhibitor (IC50 0.13 μM), low toxicity in HepAD38, hinders RNA packaging.Fórmula:C22H22BrN3O5Pureza:97.81%Forma y color:SolidPeso molecular:488.33Ref: TM-T26674
1mg39,00€5mg86,00€10mg124,00€25mg215,00€50mg320,00€100mg482,00€200mg662,00€1mL*10mM (DMSO)93,00€EHop-016
CAS:EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Fórmula:C25H30N6OPureza:98.99% - >99.99%Forma y color:SolidPeso molecular:430.55Ref: TM-T2427
5mg46,00€10mg70,00€25mg120,00€50mg202,00€100mg316,00€200mg467,00€500mg747,00€1mL*10mM (DMSO)49,00€kb NB 142-70
CAS:kb NB 142-70 is a selective protein kinase D (PKD) inhibitor (IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively).Fórmula:C11H9NO2S2Pureza:98.15% - ≥95%Forma y color:SolidPeso molecular:251.32TH5427
CAS:TH5427 is a lead NUDT5 inhibitor(MG assay IC50 = 29 nM).Fórmula:C20H20Cl2N8O3Pureza:99.54%Forma y color:SolidPeso molecular:491.33Ref: TM-T39785L
1mg92,00€2mg130,00€5mg200,00€10mg290,00€25mg495,00€50mg623,00€100mg842,00€200mg1.134,00€RKI1313
CAS:RKI1313 (RKI-1313) was a selective inhibitor for ROCK-dependent signaling, cytoskeletal changes, anchorage-independent colony formation, migration, and invasionFórmula:C17H16N4O2SPureza:99.53% - ≥95%Forma y color:SolidPeso molecular:340.4Ref: TM-T2011
1mg66,00€5mg135,00€10mg197,00€25mg349,00€50mg512,00€100mg730,00€500µg50,00€1mL*10mM (DMSO)152,00€10074-A4
CAS:10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features fromFórmula:C18H14Cl2N2O3SPureza:99.06%Forma y color:SolidPeso molecular:409.29Ref: TM-T9628
1mg56,00€2mg80,00€5mg114,00€10mg177,00€25mg318,00€50mg454,00€100mg627,00€200mg845,00€1mL*10mM (DMSO)101,00€GSK180736A
CAS:GSK180736A: GRK2 inhibitor (IC50 0.77µM), >100x selectivity vs GRKs, weak at PKA (IC50 30µM), strong vs ROCK1 (IC50 100nM).Fórmula:C19H16FN5O2Pureza:98.38% - 98.98%Forma y color:SolidPeso molecular:365.36Ref: TM-T3513
1mg39,00€2mg50,00€5mg70,00€10mg94,00€25mg161,00€50mg290,00€100mg538,00€500mg1.161,00€1mL*10mM (DMSO)62,00€K858 (Racemic)
CAS:K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.Fórmula:C13H15N3O2SPureza:>99.99%Forma y color:SolidPeso molecular:277.345-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE
CAS:5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE targets PLK1.Fórmula:C8H13N3SPureza:99.03%Forma y color:SolidPeso molecular:183.27Abemaciclib methanesulfonate
CAS:Abemaciclib methanesulfonate (LY2835219) is a specific and effective inhibitor of CDK4(IC50=2 nM) and CDK6(IC50=10 nM).
Fórmula:C27H32F2N8·CH4O3SPureza:98.69% - 99.44%Forma y color:SolidPeso molecular:602.7KB-0742 dihydrochloride
CAS:KB-0742 dihydrochloride is a potent, selective and orally inhibitor of CDK9.Fórmula:C16H27Cl2N5Pureza:99.79%Forma y color:SolidPeso molecular:360.33Ref: TM-T9446
1mg96,00€2mg143,00€5mg235,00€10mg378,00€25mg630,00€50mg898,00€100mg1.216,00€1mL*10mM (DMSO)249,00€BMS-265246
CAS:BMS-265246 is a potent and selective CDK1/2 inhibitor.Fórmula:C18H17F2N3O2Pureza:99.25% - 99.57%Forma y color:SolidPeso molecular:345.34Ref: TM-T2679
1mg34,00€5mg71,00€10mg110,00€25mg210,00€50mg318,00€100mg455,00€200mg617,00€1mL*10mM (DMSO)78,00€Alisertib
CAS:Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.Fórmula:C27H20ClFN4O4Pureza:98.31% - >99.99%Forma y color:SolidPeso molecular:518.92Ref: TM-T2241
5mg52,00€10mg92,00€25mg146,00€50mg215,00€100mg334,00€200mg430,00€500mg705,00€1mL*10mM (DMSO)59,00€BRD32048
CAS:BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation.
Fórmula:C16H22N6OPureza:99.87%Forma y color:SolidPeso molecular:314.39IXA4
CAS:IXA4 is a highly selective, nontoxic activator of IRE1/XBP1s and reduces APP secretion by activating IRE1.Fórmula:C24H28N4O4Pureza:99.8% - 99.85%Forma y color:SolidPeso molecular:436.5STF-083010
CAS:STF-083010 is a selective inhibitor of the IRE1α endonuclease.Fórmula:C15H11NO3S2Pureza:98.09% - 99.45%Forma y color:SolidPeso molecular:317.38Ref: TM-T6681
5mg49,00€10mg75,00€25mg114,00€50mg193,00€100mg349,00€200mg527,00€500mg767,00€1mL*10mM (DMSO)55,00€Cyclo(RADfK)
CAS:Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.Fórmula:C28H43N9O7Pureza:>99.99%Forma y color:SolidPeso molecular:617.7E7820
CAS:E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).Fórmula:C17H12N4O2SPureza:98.31% - 99.11%Forma y color:SolidPeso molecular:336.37Ref: TM-T4435
1mg34,00€2mg49,00€5mg65,00€10mg84,00€25mg137,00€50mg200,00€100mg321,00€200mg477,00€1mL*10mM (DMSO)80,00€EN4
CAS:EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC.Fórmula:C25H24N2O4Pureza:98.51%Forma y color:SolidPeso molecular:416.47NG 52
CAS:NG 52 (NG-52) is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p and the related Pho85p kinase.Fórmula:C16H19ClN6OPureza:98% - 99.34%Forma y color:SolidPeso molecular:346.81
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