Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(94 productos)
- CDK(500 productos)
- Detención del ciclo celular(4 productos)
- Chk(42 productos)
- DYRK(48 productos)
- Dynamin(23 productos)
- Ferroptosis(215 productos)
- HSP(169 productos)
- Integrin(224 productos)
- Kinesina(66 productos)
- LIM quinasa(19 productos)
- Asociado a microtúbulos(261 productos)
- PKC(102 productos)
- PLK(28 productos)
- ROCK(70 productos)
- Rho(2 productos)
- Wee1(15 productos)
- c-Myc(69 productos)
Mostrar 10 subcategorías más
Se han encontrado 3477 productos de "Ciclo celular / Checkpoint"
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PF-2771
CAS:<p>PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.</p>Fórmula:C29H36ClN5O4Pureza:98%Forma y color:SolidPeso molecular:554.08DNA Gyrase-IN-5
CAS:<p>DNA Gyrase-IN-5 is a potent inhibitor of DNA gyrase (IC50: 0.10 μM) and has an antibacterial effect on both wild-type and drug-resistant strains.</p>Fórmula:C25H15BrClN5Forma y color:SolidPeso molecular:500.78Syntelin
CAS:<p>Syntelin: a selective CENP-E inhibitor with an IC50 of 160 nM; distinct from GSK923295, effective on resistant mutants.</p>Fórmula:C21H20N6O2S3Forma y color:SolidPeso molecular:484.62Zalunfiban
CAS:<p>RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.</p>Fórmula:C16H18N8O2SForma y color:SolidPeso molecular:386.43MDK6204
CAS:<p>MDK6204 is a selective inhibitor of CLK1 and CLK2.</p>Fórmula:C20H20N6OPureza:98%Forma y color:SolidPeso molecular:360.41Cylindrospermopsin
CAS:<p>Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.</p>Fórmula:C15H21N5O7SForma y color:SolidPeso molecular:415.42Cdc7-IN-4
CAS:<p>Cdc7-IN-4 is a potent inhibitor of Cdc7 kinase.</p>Fórmula:C22H24F3N5O4Pureza:98%Forma y color:SolidPeso molecular:479.45Valategrast
CAS:<p>Valategrast: potent, oral dual α4β1/α4β7 integrin antagonist, may treat COPD and asthma.</p>Fórmula:C30H32Cl3N3O4Pureza:98%Forma y color:SolidPeso molecular:604.95Cyclapolin 9
CAS:<p>Cyclapolin 9: Selective PLK1 inhibitor, IC50 500 nM, ATP-competitive, inactive against other kinases.</p>Fórmula:C9H4F3N3O4SPureza:99.5%Forma y color:SolidPeso molecular:307.21Binucleine 2
CAS:<p>Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.</p>Fórmula:C13H11ClFN5Forma y color:SolidPeso molecular:291.71IRE1α kinase-IN-7
CAS:<p>IRE1α kinase-IN-7 is a chemical compound functioning as an inhibitor of IRE1α kinase, primarily utilized in the research of diseases related to endoplasmic</p>Fórmula:C28H25F3N6OForma y color:SolidPeso molecular:518.531-Methylcytosine
CAS:<p>1-Methylcytosine (4-amino-1-methylpyrimidin-2(1H)-one) is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired with</p>Fórmula:C5H7N3OPureza:99.88%Forma y color:SolidPeso molecular:125.13ANI-7
CAS:<p>ANI-7, an AhR pathway activator, selectively impedes MCF-7 breast cancer cell growth (GI50: 0.56 μM).</p>Fórmula:C13H8Cl2N2Pureza:99.07%Forma y color:SolidPeso molecular:263.12WF-536 Hydrochloride
CAS:<p>WF-536 Hydrochloride, a novel inhibitor of ROCK, inhibits tumour metastasis in some animal models.</p>Fórmula:C14H16ClN3OForma y color:SolidPeso molecular:277.75BA-1049
CAS:<p>BA-1049 is a selective ROCK2 inhibitor.</p>Fórmula:C16H21N3O2SForma y color:SolidPeso molecular:319.42M443
CAS:<p>M443 is a potent small molecule inhibitor of MRK that inhibits radiation-induced activation of p38 and Chk2 and can be used in cancer research.</p>Fórmula:C31H30F3N7O2Pureza:98.95%Forma y color:SolidPeso molecular:589.61XIE18-6
CAS:<p>XIE18-6 is a novel INK4C inhibitor that blocks p18 activity and promotes ex vivo expansion of human and murine hematopoietic stem cells.</p>Fórmula:C18H15NO6SPureza:99.712%Forma y color:SolidPeso molecular:373.38CI-898 HCl
CAS:<p>CI-898 HCl: lipophilic antifolate, DHFR inhibitor, effective on methotrexate-resistant cancers, synergizes with other drugs in advanced P338 leukemia.</p>Fórmula:C19H26Cl3N5O3Forma y color:SolidPeso molecular:478.8CDK4/6-IN-14
CAS:<p>CDK4/6-IN-14: potent CDK4/6 inhibitor, IC50s 10/16 nM, >60-fold selectivity over CDKs 1/2/7/9, selective across 205 kinases.</p>Fórmula:C24H27ClFN7OForma y color:SolidPeso molecular:483.97IRE1α kinase-IN-9
CAS:<p>IRE1α kinase-IN-9 (compound 2) is a potent inhibitor of IRE-1α, demonstrating an average IC50 value of less than 0.1 μM.</p>Fórmula:C24H24N2O6Pureza:98%Forma y color:SolidPeso molecular:436.46Trimetrexate glucuronate
CAS:<p>Trimetrexate glucuronate, a folic acid foe, blocks DNA/RNA synthesis by inhibiting purine and thymidylic acid production, may fight tumors.</p>Fórmula:C25H33N5O10Forma y color:SolidPeso molecular:563.564TCS 2314
CAS:<p>TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).</p>Fórmula:C28H34N4O6Pureza:98%Forma y color:SolidPeso molecular:522.59Thiarabine
CAS:<p>Thiarabine displays effective anti-tumor activity. It also inhibition of DNA synthesis.</p>Fórmula:C9H13N3O4SPureza:98%Forma y color:SolidPeso molecular:259.28ROCK-IN-4
CAS:<p>ROCK-IN-4: Inhibits ROCK, sustains NO release, disrupts F-actin, hinders HTM cell respiration, aids glaucoma research.</p>Fórmula:C20H26ClFN4O7SForma y color:SolidPeso molecular:520.96USP28-IN-2
CAS:<p>USP28-IN-2 selectively inhibits USP28 (IC50=0.3 μM), degrades c-Myc, kills cancer cells, lowers ankyrin-1/2, and enhances Regorafenib effects.</p>Fórmula:C23H20Cl2N2O3SForma y color:SolidPeso molecular:475.39IRE1α kinase-IN-8
CAS:<p>IRE1α kinase-IN-8, a benzoheterocyclecarboxaldehyde derivative, serves as a potent inhibitor of IRE-1α.</p>Fórmula:C23H22N2O5Pureza:98%Forma y color:SolidPeso molecular:406.43Dihydro-5-azacytidine acetate
CAS:<p>Dihydro-5-azacytidine acetate (DHAC), a nucleoside analog, becomes integrated into DNA, thereby inhibiting DNA methylation, and exhibits antitumor activity [1</p>Fórmula:C10H18N4O7Pureza:98%Forma y color:SolidPeso molecular:306.27Cdc7-IN-5
CAS:<p>Cdc7-IN-5: potent Cdc7 serine-threonine kinase inhibitor, critical for starting DNA replication.</p>Fórmula:C25H23N3O5Pureza:97.15%Forma y color:SolidPeso molecular:445.47JH-XIV-68-3
CAS:<p>JH-XIV-68-3: Selective DYRK1A/B inhibitor; effective in HNSCC cell lines.</p>Fórmula:C21H17F3N8OForma y color:SolidPeso molecular:454.41CM03
CAS:<p>CM03 is a cell-selective G-quadruplex ligand with anti-cancer activity, stabilizing G4 genes, useful in pancreatic cancer research.</p>Fórmula:C34H44N6O6Pureza:98.65%Forma y color:SolidPeso molecular:632.75Akt1&PKA-IN-2
CAS:<p>Akt1&PKA-IN-2 ((R)-29) inhibits AKT1, PKAα, CDK2 with IC50s: 0.007, 0.01, 0.69 µM respectively.</p>Fórmula:C20H17Cl2N3OForma y color:SolidPeso molecular:386.27CDK1-IN-1
CAS:<p>CDK1-IN-7 inhibits CDK1 at 161.2 nM, triggers p53-dependent apoptosis, and selectively targets tumor growth.</p>Fórmula:C27H23N5O3Forma y color:SolidPeso molecular:465.5Werner syndrome RecQ helicase-IN-4
CAS:<p>Werner syndrome RecQ helicase-IN-4 is a WRN inhibitor with anticancer and anti-proliferative activity, used in colorectal and gastric cancer research.</p>Fórmula:C32H33F3N8O5Pureza:98.27%Forma y color:SolidPeso molecular:666.65FLDP-5
CAS:<p>FLDP-5: BBB-penetrant curcuminoid, induces ROS, DNA damage, S phase arrest, suppresses tumors in LN-18 cells.</p>Fórmula:C21H21NO5Forma y color:SolidPeso molecular:367.45-Aminouridine
CAS:<p>5-Aminouridine (4-Chloro-2-isopropyl-5-methylphenol(chlorothymol)) modifies nucleobases and is incorporated into the target DNA.</p>Fórmula:C9H13N3O6Pureza:99.53%Forma y color:SolidPeso molecular:259.22CDK7-IN-2
CAS:<p>CDK7-IN-2 inhibits CDK7, essential for RNA polymerase II activation and cell cycle control, with cancer research potential.</p>Fórmula:C26H39N7O3Forma y color:SolidPeso molecular:497.63CB10-277
CAS:<p>CB10-277 is a synthetic anti-cancer drug related to dacarbazine that alkylates DNA, inhibits DNA replication and repair, and may block DNA synthesis.</p>Fórmula:C9H11N3O2Forma y color:SolidPeso molecular:193.2Edatrexate
CAS:<p>Edatrexate (CGP 30694), a Methotrexate analog, combats MTX-resistant tumors and researches various cancers.</p>Fórmula:C22H25N7O5Forma y color:SolidPeso molecular:467.48Balamapimod
CAS:<p>Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.</p>Fórmula:C30H32ClN7OSPureza:98%Forma y color:SolidPeso molecular:574.14HBV-IN-21
CAS:<p>HBV-IN-21 inhibits HBV DNA replication (IC50: 2.2 μM) and binds HBV capsid protein well (KD: 60.0 μM).</p>Fórmula:C17H17FN4OS2Forma y color:SolidPeso molecular:376.47CDK4/6-IN-7
CAS:<p>CDK4/6-IN-7 is an oral, potent CDK4/6 inhibitor with IC50s of 1.58/4.09 nM, crucial for breast cancer studies.</p>Fórmula:C18H18ClN5O3Forma y color:SolidPeso molecular:387.82BI8622
CAS:<p>BI8622 is a HUWE1 antagonist that restores levels of RP2 mutants in retinal cell lines and inhibits cellular activation of NLRP3 and AIM2 inflammatory vesicles.</p>Fórmula:C25H26N6OPureza:98.28%Forma y color:SolidPeso molecular:426.51DHODH-IN-4
CAS:<p>DHODH-IN-4 inhibits human & Plasmodium DHODH; IC50: 4 μM (Pf), 0.18 μM (Hs). It has antimalarial properties.</p>Fórmula:C17H12Cl2N2O2Pureza:99.34%Forma y color:SolidPeso molecular:347.2Enocitabine
CAS:<p>Enocitabine is a nucleoside analog.</p>Fórmula:C31H55N3O6Pureza:97.22%Forma y color:SolidPeso molecular:565.78CAY10760
CAS:<p>CAY10760 inhibits RAD51-BRCA2 interaction (EC50=19 μM), reduces homologous recombination by 54%, and hinders BxPC-3/Capan-1 cancer cell proliferation.</p>Fórmula:C28H24ClN3O3Forma y color:SolidPeso molecular:485.96SPC-839
CAS:<p>SPC-839 is an IKK-2 Inhibitor with oral activity.</p>Fórmula:C18H14N4O3SForma y color:SolidPeso molecular:366.39DHODH-IN-19
CAS:<p>DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)</p>Fórmula:C22H18ClF6N3O3Forma y color:SolidPeso molecular:521.84ARN22089
CAS:<p>ARN22089 is an oral active CDC42 GTPase interaction inhibitor that blocks tumour growth in BRAF mutant mouse melanoma models and PDXs in vivo.</p>Fórmula:C23H27N5Pureza:98.37%Forma y color:SolidPeso molecular:373.49αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
<p>αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).</p>Fórmula:C28H35F3N6O8SPureza:98%Forma y color:SolidPeso molecular:672.67MTH1-IN-2
CAS:<p>MTH1-IN-2 is an inhibitor of MutT homolog 1 (MTH1), with anti-tumor activity.</p>Fórmula:C24H27N3O5SPureza:98%Forma y color:SolidPeso molecular:469.55TH470
CAS:<p>TH470, a potent and highly selective inhibitor of LIM kinase 1/2 (LIMK1/2), demonstrates specificity with IC50 values of 9.8 nM for LIMK1 and 13 nM for LIMK2,</p>Fórmula:C30H31N5O5S2Forma y color:SolidPeso molecular:605.73Mequindox
CAS:<p>Mequindox is an antimicrobial agent [1]. Mequindox, as an inhibitor of DNA synthesis, induces genotoxicity and carcinogenicity in mice [2].</p>Fórmula:C11H10N2O3Forma y color:SolidPeso molecular:218.21Phen-DC3
CAS:<p>Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases (IC50s of 65±6 and 50±10 nM, respectively).</p>Fórmula:C34H26N6O2Pureza:98%Forma y color:SolidPeso molecular:550.61cp028
CAS:<p>cp028 inhibits pre-mRNA splicing in vitro.</p>Fórmula:C23H17FN2O4Forma y color:SolidPeso molecular:404.39Aurora kinase inhibitor-10
CAS:<p>Aurora kinase inhibitor-10 is an orally active Aurora B inhibitor (IC50: 8 nM) that exhibits antitumour effects.</p>Fórmula:C21H19F5N6O4SForma y color:SolidPeso molecular:546.47Dyrk1A-IN-5
CAS:<p>Potent DYRK1A inhibitor with IC50s: 6 nM overall, 0.5 μM SF3B1, 2.1 μM tau phosphorylation. Useful for Down syndrome studies.</p>Fórmula:C16H9IN2O2Forma y color:SolidPeso molecular:388.16Crozbaciclib fumarate
CAS:<p>Crozbaciclib fumarate is a CDK4/6 inhibitor with IC 50 s of 3 and 1 nM, respectively.</p>Fórmula:C32H34F2N6O4Forma y color:SolidPeso molecular:604.65SR31527
CAS:<p>SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.</p>Fórmula:C15H14ClN3OSPureza:98%Forma y color:SolidPeso molecular:319.81Antitumor agent-84
<p>Antitumor agent-84 stabilizes G-quadruplex DNA, exhibits potent anti-tumor effects.</p>Fórmula:C24H31N7Forma y color:SolidPeso molecular:417.55CRT-0105446
CAS:<p>CRT-0105446 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.</p>Fórmula:C20H18F3N3O2SPureza:98%Forma y color:SolidPeso molecular:421.44TCS 2312
CAS:<p>checkpoint kinase 1 (chk1) inhibitor</p>Fórmula:C25H24N4O2Pureza:98%Forma y color:SolidPeso molecular:412.48Trimetrexate
CAS:<p>Trimetrexate is an effective competitive inhibitor of bacterial, protozoan, and mammalian dihydrofolate reductase.</p>Fórmula:C19H23N5O3Pureza:98%Forma y color:SolidPeso molecular:369.42Akt1&PKA-IN-1
CAS:<p>Akt1&PKA-IN-1 inhibits Akt/PKA: IC50 = 0.03μM (PKAa), 0.11μM (Akt), 9.8μM (CDK2); selective for CDK2.</p>Fórmula:C20H17Cl2N3OForma y color:SolidPeso molecular:386.27Laflunimus
CAS:<p>Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin secretion in vitro and in vivo,by interfering with pyrimidine metabolism,neuralgia.</p>Fórmula:C15H13F3N2O2Pureza:99.86%Forma y color:SolidPeso molecular:310.275-Ethynyluridine
CAS:<p>5-Ethynyluridine marks new RNA for RICK, capturing proteins on various RNAs, even nonpolyadenylated types.</p>Fórmula:C11H12N2O6Pureza:99.78%Forma y color:SolidPeso molecular:268.22Aurora Kinases-IN-3
CAS:<p>Aurora Kinases-IN-3 is an oral AURKB inhibitor that disrupts its mitotic localization, not its H3 Ser10 phosphorylation.</p>Fórmula:C20H16F3N3O4Forma y color:SolidPeso molecular:419.35SRPIN-803
CAS:<p>SRPIN-803 is a selective dual SRPK1 and CK2 inhibitor.</p>Fórmula:C14H9F3N4O3SPureza:98%Forma y color:SolidPeso molecular:370.31GSK317354A
CAS:<p>GSK317354A is a GRK2 inhibitor.</p>Fórmula:C25H18F4N6OForma y color:SolidPeso molecular:494.44BOP sodium
CAS:<p>BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.</p>Fórmula:C25H29N3NaO7SForma y color:SolidPeso molecular:538.57Integrin-IN-2
CAS:<p>Integrin-IN-2, an oral αv integrin blocker, enhances αvβ6/3/5/8 affinities with pIC50s: 7.8/8.4/8.4/7.4.</p>Fórmula:C27H30N4O3Pureza:98%Forma y color:SolidPeso molecular:458.55360A iodide
CAS:<p>360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).</p>Fórmula:C27H23I2N5O2Pureza:98%Forma y color:SolidPeso molecular:703.31NSC 625987
CAS:<p>Cyclin-dependent kinase (cdk) 4 inhibitor</p>Fórmula:C15H13NO2SPureza:98%Forma y color:SolidPeso molecular:271.33CDK8-IN-4
CAS:<p>CDK8-IN-4 is an inhibitor of CDK8 (IC50: 0.2 nM).</p>Fórmula:C20H18N4OForma y color:SolidPeso molecular:330.38CDK12-IN-3
CAS:<p>CDK12-IN-3 is a CDK12 inhibitor with anti-tumor activity and can be used for the study of malignant tumors.</p>Fórmula:C23H28F2N8OPureza:99.85%Forma y color:SolidPeso molecular:470.52DNA Gyrase-IN-4
CAS:<p>DNA Gyrase-IN-4 inhibits DNA cyclooxygenase (IC50: 0.13 μM) and is effective against Salmonella and E. coli.</p>Fórmula:C22H15Cl2NO4SForma y color:SolidPeso molecular:460.33FUBP1-IN-2
CAS:<p>FUBP1-IN-2 hinders FUBP1, affects c-Myc and p21 expression, and depletes polyamines.</p>Fórmula:C26H26ClN3O4Forma y color:SolidPeso molecular:479.96Cdc7-IN-1
CAS:<p>Cdc7-IN-1: selective ATP-competitive Cdc7 kinase inhibitor; IC50 0.6 nM at 1mM ATP; induces cancer cell death.</p>Fórmula:C21H16ClN3O4Forma y color:SolidPeso molecular:409.82IXA6
CAS:<p>IXA6 is an IRE1/XBP1s agonist with potential vasoprotective activity for the study of neurodegenerative diseases such as Parkinson's disease.</p>Fórmula:C22H20ClN3O3SPureza:98.63%Forma y color:SolidPeso molecular:441.93KSI-3716
CAS:<p>KSI-3716 is a c-Myc inhibitor, a bladder chemotherapy agent that blocks the formation of complexes between c-MYC/MAX and target gene promoters.</p>Fórmula:C17H11BrCl2N2O2Pureza:98.94%Forma y color:SolidPeso molecular:426.09CLK1/2-IN-3
CAS:<p>CLK1/2-IN-3 (Cpd-3) is a CLK1 and CLK2 inhibitor with antiproliferative activity that inhibits the activity of CLK and SRPK.</p>Fórmula:C21H21N5O2Pureza:99.04%Forma y color:SolidPeso molecular:375.42CDK12-IN-E9
CAS:<p>CDK12-IN-E9 is a potent and selective covalent CDK12 inhibitor and non-covalent CDK9 inhibitor while avoiding ABC transporter-mediated efflux.</p>Fórmula:C24H30N6O2Forma y color:SolidPeso molecular:434.53PD-1/PD-L1-IN-NP19
CAS:<p>PD-1/PD-L1-IN-NP19: a PD-1/PD-L1 inhibitor with 12.5 nM IC50, may boost antitumor immunity.</p>Fórmula:C33H31ClN2O4Pureza:98%Forma y color:SolidPeso molecular:555.06AS2863619 free base
CAS:<p>AS2863619 free base enables the conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells.</p>Fórmula:C16H12N8OForma y color:SolidPeso molecular:332.325,10-Dideazaaminopterin
CAS:<p>5,10-Dideazaaminopterin is an antileukemic drug.</p>Fórmula:C21H22N6O5Pureza:98%Forma y color:SolidPeso molecular:438.44HBV-IN-14
CAS:<p>HBV-IN-14: a pyridinopyrimidinone, potent cccDNA inhibitor for HBV study (patent WO2021190502A1, comp 5).</p>Fórmula:C22H21ClN2O5Forma y color:SolidPeso molecular:428.87Chlorasquin
CAS:<p>Chlorasquin is a dihydrofolate reductase inhibitor.</p>Fórmula:C20H19ClN6O5Pureza:98%Forma y color:SolidPeso molecular:458.86Centrinone-B
CAS:<p>Centrinone-B (LCR-323) is a Plk4 inhibitor with potential anticancer activity for the study of triple-negative breast cancer.</p>Fórmula:C27H27F2N7O5S2Pureza:98.71%Forma y color:SolidPeso molecular:631.67MMV688845
CAS:<p>MMV688845: NTM RNA polymerase inhibitor, kills Mycobacterium abscessus, and fights TB.</p>Fórmula:C24H25N3O3SForma y color:SolidPeso molecular:435.54L 888607 Racemate
CAS:<p>L 888607 Racemate blocks DP1 and TP receptors with 132 nM and 17 nM affinity.</p>Fórmula:C19H15ClFNO2SForma y color:SolidPeso molecular:375.84Ilorasertib hydrochloride
CAS:<p>Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s:</p>Fórmula:C25H22ClFN6O2SPureza:98.45%Forma y color:SolidPeso molecular:525CLK1-IN-1
CAS:<p>CLK1-IN-1 is a potent and selective inhibitor of the Cdc2-like kinase 1 (CLK1; IC50: 2 nM).</p>Fórmula:C24H16FN5OForma y color:SolidPeso molecular:409.42THZ1-R
CAS:<p>THZ1-R is a non-covalent active analogue of THZ1, with the acrylamide group removed from THZ1, not covalently bind to the C312 cysteine residue of CDK7.</p>Fórmula:C31H30ClN7O2Pureza:98%Forma y color:SolidPeso molecular:568.07Antibacterial agent 124
CAS:<p>Antibacterial agent 124 inhibits Sa ProRS with an IC50 of 0.18 μM.</p>Fórmula:C16H17ClFN3O2Forma y color:SolidPeso molecular:337.78JA2131
CAS:<p>JA2131: Small PARG inhibitor, IC50 0.4μM, induces DNA damage, stalls replication, kills cancer cells.</p>Fórmula:C13H19N5O2S2Forma y color:SolidPeso molecular:341.45Poloxipan
CAS:<p>Poloxipan inhibits PLK1 (IC50: 3.2µM), PLK2 (1.7µM), PLK3 (3µM); minimal effect on Chk2, STAT1, STAT5b, Lck.</p>Fórmula:C14H10BrN3O3SForma y color:SolidPeso molecular:380.22Kif15-IN-1
CAS:<p>Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.</p>Fórmula:C20H22N4O5SPureza:99.39% - 99.39%Forma y color:SolidPeso molecular:430.48KIF18A-IN-3
CAS:<p>KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.</p>Fórmula:C28H38N4O5S2Pureza:98.45%Forma y color:SolidPeso molecular:574.76BMS-688521
CAS:<p>BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.</p>Fórmula:C26H19Cl2N5O4Pureza:98.87%Forma y color:SolidPeso molecular:536.37CDK8/19-IN-51
CAS:<p>CDK8/19-IN-51 is a CDK8 and CDK19 inhibitor with anticancer activity, used in research on colorectal and gastric cancers.</p>Fórmula:C23H22N6O2Pureza:98.65% - 99.62%Forma y color:SoildPeso molecular:414.46UR-3216
CAS:<p>UR-3216 is a prodrug, selectively antagonizing GPIIb/IIIa receptors orally, with its active form, UR-2992, binding tightly to platelets.</p>Fórmula:C27H29N7O7Pureza:98%Forma y color:SolidPeso molecular:563.56
