
Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(115 productos)
- CDK(546 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(227 productos)
- HSP(180 productos)
- Integrin(268 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(274 productos)
- PKC(126 productos)
- PLK(25 productos)
- ROCK(62 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
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Se han encontrado 3904 productos de "Ciclo celular / Checkpoint"
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THZ1
CAS:THZ1 (CDK7 inhibitor) is a selective inhibitor of CDK7, binding to the Cys residue located at the outer end of the classical kinase domain. Cost-effective and quality-assured.Fórmula:C31H28ClN7O2Pureza:97.42% - 99.27%Forma y color:SolidPeso molecular:566.05MLN8054
CAS:MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.Fórmula:C25H15ClF2N4O2Pureza:98.07% - 98.26%Forma y color:SolidPeso molecular:476.86Ref: TM-T6315
1mg50,00€2mg67,00€5mg84,00€10mg120,00€25mg220,00€50mg356,00€100mg537,00€1mL*10mM (DMSO)88,00€CCT245737
CAS:CCT245737 is an orally active, selective Chk1 inhibitor, and is >1,000-fold selective over CHK2 and CDK1.Cost-effective and quality-assured.Fórmula:C16H16F3N7OPureza:98.28% - 99.93%Forma y color:SolidPeso molecular:379.34Ref: TM-T7080
1mg37,00€2mg49,00€5mg79,00€10mg113,00€25mg213,00€50mg350,00€100mg523,00€1mL*10mM (DMSO)87,00€Cucurbitacin B
CAS:Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Fórmula:C32H46O8Pureza:97.1% - 99.93%Forma y color:SolidPeso molecular:558.70Y16
CAS:Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.Fórmula:C24H20N2O3Pureza:98.26% - 99.85%Forma y color:SolidPeso molecular:384.43Ref: TM-T3553
1mg34,00€2mg48,00€5mg70,00€10mg109,00€25mg177,00€50mg263,00€100mg389,00€1mL*10mM (DMSO)77,00€MC180295
CAS:MC180295 ((rel)-MC180295) is a novel potent, highly selective CDK9 inhibitor (IC50: 5 nM), displays >22-fold selectivity over other CDKs.Fórmula:C17H18N4O3SPureza:99.84%Forma y color:SolidPeso molecular:358.41Ref: TM-T5533
1mg52,00€5mg124,00€10mg177,00€25mg301,00€50mg424,00€100mg605,00€200mg797,00€1mL*10mM (DMSO)136,00€Cyclo(-RGDfK)
CAS:Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.Fórmula:C27H41N9O7Pureza:95.29% - >99.99%Forma y color:SolidPeso molecular:603.67CID44216842
CAS:CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.Fórmula:C22H20BrN3O3SPureza:99.66%Forma y color:SolidPeso molecular:486.38Ref: TM-T8930
2mg34,00€5mg50,00€10mg85,00€25mg159,00€50mg244,00€100mg359,00€200mg512,00€1mL*10mM (DMSO)55,00€6-AZATHYMINE
CAS:6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.Fórmula:C4H5N3O2Pureza:99.47%Forma y color:SolidPeso molecular:127.13-Methylcytidine
CAS:3-Methylcytidine as biomarkers of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.Fórmula:C10H15N3O5Pureza:99.52%Forma y color:SolidPeso molecular:257.24(1E)-CFI-400437 dihydrochloride
CAS:(1E)-CFI-400437 dihydrochloride (CFI-400437 dihydrochloride) is a selective and potent polo-like kinase 4 (PLK4) inhibitor.Fórmula:C29H30Cl2N6O2Pureza:97.08%Forma y color:SolidPeso molecular:565.5Ref: TM-T22288
1mg77,00€5mg160,00€10mg236,00€25mg394,00€50mg550,00€100mg782,00€1mL*10mM (DMSO)197,00€TH-257
CAS:TH-257 is a Potent and selective allosteric LIMK 1/2 inhibitor(LIMK1 and LIMK2, IC50 of 84 nM and 39 nM).Fórmula:C24H26N2O3SPureza:98.23%Forma y color:SolidPeso molecular:422.54CRT0044876
CAS:CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.Fórmula:C9H6N2O4Pureza:98.27% - 98.98%Forma y color:Brown PowderPeso molecular:206.155-Fluoroorotic acid
CAS:5-Fluoroorotic acid is an inhibitor of thymidylate synthase.Fórmula:C5H3FN2O4Pureza:99.7% - >99.99%Forma y color:White To Pale Yellow PowderPeso molecular:174.09RI-2
CAS:RI-2, a potent RAD51 inhibitor, has a 44.17 μM IC50 and selectively blocks human HR repair.Fórmula:C21H18Cl2N2O4Pureza:99.63% - 99.86%Forma y color:SolidPeso molecular:433.28Ref: TM-T2628
1mg70,00€2mg92,00€5mg152,00€10mg266,00€25mg413,00€50mg605,00€100mg863,00€1mL*10mM (DMSO)166,00€Quarfloxin
CAS:Quarfloxin (CX-3543), a fluoroquinolone, inhibits neuroblastoma with nanomolar IC50, disrupting nucleolin and G-quadruplex DNA.Fórmula:C35H33FN6O3Pureza:99.77%Forma y color:SolidPeso molecular:604.67Ref: TM-T16703
1mg71,00€2mg92,00€5mg152,00€10mg236,00€25mg380,00€50mg530,00€100mg708,00€1mL*10mM (DMSO)212,00€Ro5-3335
CAS:Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins.Fórmula:C13H10ClN3OPureza:99.42% - 99.87%Forma y color:SolidPeso molecular:259.69XL228
CAS:XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Fórmula:C22H31N9OPureza:99.07%Forma y color:SolidPeso molecular:437.54Ref: TM-T17267
1mg52,00€2mg73,00€5mg94,00€10mg141,00€25mg244,00€50mg371,00€100mg552,00€1mL*10mM (DMSO)104,00€Tozasertib
CAS:Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).Fórmula:C23H28N8OSPureza:99.99%Forma y color:SolidPeso molecular:464.59SAR-020106
CAS:SAR-020106 is a potent, ATP-competitive, and selective CHK1 inhibitor with an IC50 of 13.3 nmol/L on the isolated human enzyme.Fórmula:C19H19ClN6OPureza:97.78%Forma y color:SolidPeso molecular:382.85Tipiracil hydrochloride
CAS:Tipiracil hydrochloride (MA-1 hydrochloride) is a thymidine phosphorylase inhibitor (TPI).Fórmula:C9H12Cl2N4O2Pureza:98.13% - ≥95%Forma y color:SolidPeso molecular:279.12THZ2
CAS:THZ2 (CDK7-IN-1), an analog of THZ1, is a potent and selective CDK7 inhibitor(IC50:13.9 nM),with the potential to treat Triple-negative breast cancer (TNBC).Fórmula:C31H28ClN7O2Pureza:98.28%Forma y color:SolidPeso molecular:566.05Madrasin
CAS:Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.Fórmula:C16H17N5O2Pureza:99.06% - 99.61%Forma y color:SolidPeso molecular:311.34Dimethylenastron
CAS:Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.Fórmula:C16H18N2O2SPureza:98.07%Forma y color:SolidPeso molecular:302.39Ref: TM-T3118
1mg34,00€2mg46,00€5mg58,00€10mg93,00€25mg147,00€50mg222,00€100mg334,00€1mL*10mM (DMSO)64,00€SCH900776 (S-isomer)
CAS:SCH900776 S-isomer (MK-8776 S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).Fórmula:C15H18BrN7Pureza:99.88%Forma y color:SolidPeso molecular:376.25Ref: TM-T3700
1mg50,00€2mg66,00€5mg90,00€10mg146,00€25mg250,00€50mg403,00€100mg593,00€1mL*10mM (DMSO)108,00€THZ531
CAS:THZ531 is a covalent inhibitor of both CDK12(IC50=158 nM) and CDK13(IC50=69 nM).Fórmula:C30H32ClN7O2Pureza:97.17% - 99.86%Forma y color:SolidPeso molecular:558.07Ref: TM-T4293
1mg59,00€2mg86,00€5mg105,00€10mg144,00€25mg313,00€50mg447,00€100mg650,00€500mg1.341,00€1mL*10mM (DMSO)130,00€RAD51-IN-1
CAS:Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.Fórmula:C22H16ClN3OPureza:99.95%Forma y color:SolidPeso molecular:373.83CBFβ Inhibitor
CAS:CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.Fórmula:C12H14N2OSPureza:96.50%Forma y color:SolidPeso molecular:234.32NITD-2
CAS:NITD-2 is a DENV RdRp inhibitor with poor cell membrane penetration; no vaccine or antiviral for DENV exists.Fórmula:C23H19N3O4SPureza:98.03% - 99.46%Forma y color:SolidPeso molecular:433.48Ref: TM-T8886
1mg74,00€5mg170,00€10mg274,00€25mg472,00€50mg655,00€100mg944,00€200mg1.264,00€1mL*10mM (DMSO)188,00€Monastrol
CAS:Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Fórmula:C14H16N2O3SPureza:98.02% - 98.59%Forma y color:SolidPeso molecular:292.35Ref: TM-T4048
1mg46,00€5mg73,00€10mg92,00€25mg178,00€50mg295,00€100mg477,00€500mg1.018,00€1mL*10mM (DMSO)93,00€AUZ 454
CAS:AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50/18.6/15.4/9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.Fórmula:C24H26F3N7O2Pureza:99.59%Forma y color:SolidPeso molecular:501.5CX-5461
CAS:CX5461 is an orally rRNA synthesis inhibitor that inhibits Pol I-driven rRNA transcription. CX5461 has antitumor activity. Cost-effective and quality-assured.Fórmula:C27H27N7O2SPureza:95.44% - 99.4%Forma y color:SolidPeso molecular:513.61BVDV-IN-1
CAS:BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM.Fórmula:C20H22N4OPureza:98.43%Forma y color:SolidPeso molecular:334.41Ref: TM-T9103
1mg38,00€5mg86,00€10mg124,00€25mg241,00€50mg355,00€100mg507,00€200mg687,00€1mL*10mM (DMSO)95,00€PND-1186
CAS:PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Fórmula:C25H26F3N5O3Pureza:99.14% - 99.75%Forma y color:SolidPeso molecular:501.5OSU-T315
CAS:OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.Fórmula:C30H30F3N5OPureza:98.69%Forma y color:SolidPeso molecular:533.59Ref: TM-T5485
1mg88,00€5mg187,00€10mg298,00€25mg533,00€50mg755,00€100mg1.008,00€200mg1.359,00€1mL*10mM (DMSO)220,00€HMN-176
CAS:HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1).Fórmula:C20H18N2O4SPureza:98.92% - 98.99%Forma y color:SolidPeso molecular:382.43Ref: TM-T3643
1mg40,00€2mg52,00€5mg84,00€10mg113,00€25mg178,00€50mg333,00€100mg495,00€500mg1.071,00€1mL*10mM (DMSO)74,00€PHA-680632
CAS:PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.Fórmula:C28H35N7O2Pureza:98.2%Forma y color:SolidPeso molecular:501.62Purvalanol B
CAS:Purvalanol B (NG 95) is a CDK inhibitor that inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively)Fórmula:C20H25ClN6O3Pureza:98.95%Forma y color:SolidPeso molecular:432.9Ref: TM-T7167
1mg34,00€2mg46,00€5mg67,00€10mg90,00€25mg130,00€50mg203,00€100mg305,00€200mg447,00€1mL*10mM (DMSO)75,00€ARQ 621
CAS:ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.Fórmula:C28H24Cl2FN5O2Pureza:97.01% - 98.38%Forma y color:SolidPeso molecular:552.43Palbociclib monohydrochloride
CAS:Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6, with no inhibition against a panel of 36 additional protein kinasesFórmula:C24H29N7O2·HClPureza:99.73% - >99.99%Forma y color:SolidPeso molecular:483.99Nolatrexed
CAS:Nolatrexed is a thymidylate synthase inhibitor with potential anticancer activity.Fórmula:C14H12N4OSPureza:97.53%Forma y color:SolidPeso molecular:284.34Ref: TM-T4228
1mg39,00€2mg52,00€5mg86,00€10mg140,00€25mg226,00€50mg408,00€100mg600,00€1mL*10mM (DMSO)90,00€Rac1 Inhibitor W56 acetate(1095179-01-3 free base)
Rac1 Inhibitor W56 acetate(1095179-01-3 free base) is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activationFórmula:C76H121N19O25SPureza:98.96%Forma y color:SolidPeso molecular:1732.95CVT-313
CAS:CVT-313 (NG-26) is a potent, selective, reversible, and ATP-competitive inhibitor.Fórmula:C20H28N6O3Pureza:97.46% - 97.97%Forma y color:SolidPeso molecular:400.47GW779439X
CAS:GW779439X is an inhibitor of CDK.Fórmula:C22H21F3N8Pureza:97.87%Forma y color:SolidPeso molecular:454.45Ref: TM-T8866
1mg58,00€2mg82,00€5mg113,00€10mg178,00€25mg404,00€50mg592,00€100mg845,00€1mL*10mM (DMSO)124,00€Raltitrexed
CAS:Raltitrexed (D1694)(IC50 of 9 nM), a thymidylate synthase inhibitor, is used for the inhibition of L1210 cell growth.Fórmula:C21H22N4O6SPureza:98.99% - 99.29%Forma y color:Yellow Crystalline PowderPeso molecular:458.49AMG 900
CAS:AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.Fórmula:C28H21N7OSPureza:98.4% - 99.51%Forma y color:SolidPeso molecular:503.58Ref: TM-T6380
1mg49,00€5mg92,00€10mg158,00€25mg286,00€50mg442,00€100mg645,00€500mg1.341,00€1mL*10mM (DMSO)100,00€MKC3946
CAS:MKC3946 is an effective and soluble IRE1α inhibitor which triggered modest growth inhibition in multiple myeloma cell lines.Fórmula:C21H20N2O3SPureza:99.65%Forma y color:SolidPeso molecular:380.46Ref: TM-TQ0101
1mg50,00€2mg70,00€5mg92,00€10mg152,00€25mg295,00€50mg447,00€100mg670,00€200mg888,00€1mL*10mM (DMSO)104,00€2′-O-Methylcytidine
CAS:2′-O-Methylcytidine inhibits NS5B-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.Fórmula:C10H15N3O5Pureza:99.72%Forma y color:SolidPeso molecular:257.24Palbociclib Isethionate
CAS:Palbociclib Isethionate (PD 0332991 isethionate) 是一种高选择性的CDK4/6抑制剂,IC50为11 nM 和16 nM。它对一组 36 种额外的蛋白激酶没有抑制作用。Fórmula:C24H29N7O2·C2H6O4SPureza:99.01% - 99.27%Forma y color:SolidPeso molecular:573.66ML264
CAS:ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.Fórmula:C17H21ClN2O4SPureza:99.33% - 99.45%Forma y color:SolidPeso molecular:384.88CCT241736
CAS:CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3Fórmula:C22H23Cl2N7Pureza:96.2% - 99.81%Forma y color:SolidPeso molecular:456.37Ara-G
CAS:Ara-G, a deoxyguanosine analog, inhibits DNA synthesis, targeting T cell leukemia by converting to araGTP.Fórmula:C10H13N5O5Pureza:98.74%Forma y color:Slightly Off White To White PowderPeso molecular:283.24Didox
CAS:Didox (NSC-324360), a synthetic RR inhibitor, lowers oxidative injury markers in HIV-related dementia.Fórmula:C7H7NO4Pureza:99.83%Forma y color:SolidPeso molecular:169.13T56-LIMKi
CAS:T56-LIMKi (T5601640) is a selective inhibitor of LIMK2.Fórmula:C19H14F3N3O3Pureza:98.39% - 99.57%Forma y color:SolidPeso molecular:389.33TP-353
CAS:TP-353 (EOS-61973) is a CDK7 inhibitor.Fórmula:C35H30FNO3Pureza:99.12%Forma y color:SolidPeso molecular:531.62Ref: TM-T22440
1mg43,00€5mg80,00€10mg129,00€25mg225,00€50mg314,00€100mg432,00€200mg597,00€1mL*10mM (DMSO)105,00€ENMD-2076
CAS:ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Fórmula:C21H25N7Pureza:97.63% - ≥95%Forma y color:SolidPeso molecular:375.47BI-1347
CAS:BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.Fórmula:C22H20N4OPureza:96.7% - 99.63%Forma y color:SolidPeso molecular:356.42Ref: TM-T5405
1mg40,00€5mg88,00€10mg126,00€25mg240,00€50mg439,00€100mg647,00€500mg1.359,00€1mL*10mM (DMSO)87,00€COH29
CAS:COH29 is an oral RNR-blocking thiazole that may reduce DNA synthesis and promote apoptosis, with potential cancer-treating properties.Fórmula:C22H16N2O5SPureza:97.04% - 98.92%Forma y color:SolidPeso molecular:420.44Ref: TM-T3157
1mg34,00€2mg49,00€5mg74,00€10mg113,00€25mg178,00€50mg334,00€100mg557,00€200mg790,00€1mL*10mM (DMSO)82,00€Fialuridine
CAS:Fialuridine (DRG-0098), a DNA polymerase inhibitor, shows strong anti-HBV effects both in vitro and in vivo.Fórmula:C9H10FIN2O5Pureza:99.71% - 99.88%Forma y color:Less Crystals Colourless CrystalsPeso molecular:372.09SRI-29329
CAS:SRI-29329 is a potent, specific inhibitor of CDC-like kinase (with IC50 of 78 nM, 16 nM and 86 nM for CLK1, CLK2 and CLK4, respectively).Fórmula:C20H26ClN7Pureza:99.18%Forma y color:SolidPeso molecular:399.92NSC23005
CAS:NSC23005 sodium is a p18INK inhibitor with potently promoted hematopoietic stem cell (HSC) expansion (ED50: 5.21 nM).Fórmula:C13H17NO4SPureza:>99.99%Forma y color:SolidPeso molecular:283.34Lifitegrast
CAS:Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.
Fórmula:C29H24Cl2N2O7SPureza:99.39% - 99.66%Forma y color:SolidPeso molecular:615.48TH287 hydrochloride
CAS:TH287 inhibits MTH1 (IC50: 0.8 nM), causing DNA damage in cancer cells through oxidized dNTP incorporation, leading to cytotoxicity in mouse xenografts.Fórmula:C11H11Cl3N4Pureza:>99.99%Forma y color:SolidPeso molecular:305.59ILK-IN-3
CAS:ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.Fórmula:C10H12N6OPureza:99.69%Forma y color:SolidPeso molecular:232.24Trilaciclib
CAS:Trilaciclib is a short-acting, orally effective CDK4/6 inhibitor with IC₅₀ values of 1 nM and 4 nM respectively. enhances antitumour immunity.Fórmula:C24H30N8OPureza:99.624%Forma y color:SolidPeso molecular:446.55Barasertib-HQPA
CAS:Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.
Fórmula:C26H30FN7O3Pureza:98.43% - 99.29%Forma y color:SolidPeso molecular:507.56N6,N6-Dimethyladenosine
CAS:N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.Fórmula:C12H17N5O4Pureza:98.79%Forma y color:White PowderPeso molecular:295.29Proguanil
CAS:Proguanil (Chloroguanide) is a prophylactic antimalarial drug that acts primarily through its active metabolite, Cycloguanil, which inhibits the DHFR enzyme .Fórmula:C11H16ClN5Pureza:99.6%Forma y color:SolidPeso molecular:253.73USP1-IN-2
CAS:USP1-IN-2 is a potent USP1 inhibitor with potential anti-tumor activity for the study of cancer.Fórmula:C26H22F4N6OPureza:99.69% - 99.88%Forma y color:SolidPeso molecular:510.4862'-O-Methyl-2-thiouridine
CAS:2'-O-Methyl-2-thiouridine, a purine nucleoside analog present in synthetic thermophilic bacterial tRNAs, is more selective for A than unmodified U.Fórmula:C10H14N2O5SPureza:99.89%Forma y color:SolidPeso molecular:274.29O6-Methyldeoxy guanosine
CAS:O6-Methyldeoxy guanosine, a deoxypurine nucleoside, is a weak inhibitor of the removal of O6-methylguanine from methylated DNA by rat liver enzymes in vitro.Fórmula:C11H15N5O4Pureza:99.57%Forma y color:SolidPeso molecular:281.27N6-Methyl-2'-O-methyladenosine
CAS:N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound foundFórmula:C12H17N5O4Pureza:99.97%Forma y color:SolidPeso molecular:295.292'-O-(2-Methoxyethyl)adenosine
CAS:2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.Fórmula:C13H19N5O5Pureza:99.35%Forma y color:SolidPeso molecular:325.323'-Deoxy-3'-fluoroadenosine
CAS:3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with a wide range of anti-tumor and anti-viral activity, and has inhibitory effects on tick-borneFórmula:C10H12FN5O3Pureza:99.84%Forma y color:SolidPeso molecular:269.235-Bromouridine
CAS:5-Bromouridine is a antitumor uracil derivative that induces apoptosis in cancer cells by inhibiting DNA synthesis and is also a marker for DNA and RNA.Fórmula:C9H11BrN2O6Pureza:99.89%Forma y color:White PowderPeso molecular:323.1PDD00017273
CAS:PDD00017273 is a radiosensitizing PARG) inhibitor with antitumor or activity for the study of epithelial ovaries.Fórmula:C23H26N6O4S2Pureza:99.14% - 99.21%Forma y color:SolidPeso molecular:514.62Ref: TM-T5700
5mg78,00€10mg130,00€25mg269,00€50mg403,00€100mg580,00€500mg1.198,00€1mL*10mM (DMSO)92,00€5-Hydroxyuridine
CAS:5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue with potential antitumour activity, showing cytotoxicity against human colon adenocarcinoma cell lines.Fórmula:C9H12N2O7Pureza:98.76%Forma y color:SolidPeso molecular:260.2CDK12-IN-5
CAS:CDK12-IN-5 is a potent CDK12 inhibitor with potential anticancer and antitumor activity, and can be used orally in the study of breast and ovarian cancer.Fórmula:C18H15F5N8OPureza:99.37%Forma y color:SolidPeso molecular:454.36Ref: TM-T40290
1mg157,00€5mg378,00€10mg612,00€25mg1.251,00€50mg1.972,00€100mg2.673,00€1mL*10mM (DMSO)416,00€N6-(p-Methoxybenzyl)adenosine
CAS:Nucleoside Derivatives - 6-Modified purine nucleosides; Drugs and Inhibitors; plant growth regulator, plant hormoneFórmula:C18H21N5O5Pureza:99.79%Forma y color:SolidPeso molecular:387.39Ref: TM-TNU0430
1mg141,00€2mg203,00€5mg344,00€10mg505,00€25mg797,00€50mg1.044,00€100mg1.431,00€200mg1.953,00€2',3'-Bis-(O-t-butyldimethylsilyl)uridine
CAS:2',3'-Bis-(O-t-butyldimethylsilyl)uridine is a nucleoside derivative protect the NH2/OH groups of nucleosides.inhibitory on viral replication,AIDS and herpes.Fórmula:C21H40N2O6Si2Pureza:99.88%Forma y color:SolidPeso molecular:472.722'-Deoxy-N4-methylcytidine
CAS:2’-Deoxy-N4-methylcytidine (N(3)-Methyl-2'-deoxycytidine) is a purine nucleoside analog with potential antitumor activity for the study of apoptosis.Fórmula:C10H15N3O4Pureza:99.61%Forma y color:SolidPeso molecular:241.24LSN2839567
CAS:LSN2839567 (Abemaciclib metabolite M2) is a CDK4 and CDK6 inhibitor with anticancer activity, inhibits CDK9, and can be used in breast cancer research.Fórmula:C25H28F2N8Pureza:99.14%Forma y color:SolidPeso molecular:478.549-(β-D-Xylofuranosyl)adenine
CAS:9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine hasFórmula:C10H13N5O4Pureza:99.97%Forma y color:SolidPeso molecular:267.24Rabacfosadine
CAS:Rabacfosadine (GS-9219) is a novel prodrug of PMEG, an acyclic nucleotide phosphonate, with antitumor activity for the study of lymphoma.Fórmula:C21H35N8O6PPureza:99.06% - 99.37%Forma y color:SolidPeso molecular:526.53Bexotegrast
CAS:Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).Fórmula:C27H36N6O3Pureza:99.53%Forma y color:SolidPeso molecular:492.615'-O-DMT-N4-Bz-5-Me-dC
CAS:5'-O-DMT-N4-Bz-5-Me-dC (DMT-NBZ-5-METHYL DC) is a modified nucleoside used in the synthesis of nucleoside phosphoramidites.Fórmula:C38H37N3O7Pureza:98.88%Forma y color:SolidPeso molecular:647.72DS44960156
CAS:DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.Fórmula:C20H15NO5Pureza:99.13%Forma y color:SolidPeso molecular:349.34Ref: TM-T37655
1mg73,00€5mg160,00€10mg236,00€25mg409,00€50mg595,00€100mg858,00€1mL*10mM (DMSO)170,00€Braco-19
CAS:Braco-19 is a telomerase/telomere inhibitor and an inhibitor of HAdV viral replication with antiviral activity that reduces lipid vacuolization in adipocytes, inhibits proliferation and decreases telomerase activity in human glioblastoma cells.Fórmula:C35H43N7O2Pureza:97.01%Forma y color:SolidPeso molecular:593.76RO0270608
CAS:RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.Fórmula:C24H19Cl3N2O4Pureza:98.26%Forma y color:SolidPeso molecular:505.785-Bromo-2',3',5'-tri-O-acetyluridine
CAS:5-Bromo-2',3',5'-tri-O-acetyluridine is a purine nucleoside analog that can be used to explore explore improve Parkinson's disease.Fórmula:C15H17BrN2O9Pureza:99%Forma y color:SolidPeso molecular:449.21P-2'-deoxyribose
CAS:P-2'-deoxyribose (P-Nucleoside) is a deoxyribose that is widely found in organisms.Fórmula:C11H15N3O5Pureza:99.71%Forma y color:SolidPeso molecular:269.25Ref: TM-TNU1281
1mg109,00€2mg160,00€5mg261,00€10mg374,00€25mg583,00€50mg803,00€100mg1.063,00€200mg1.431,00€2'-C-β-Methylguanosine
CAS:2'-C-beta-Methylguanosine (2'-C-Methylguanosine), with antiviral activity, inhibits dengue virus 2.Fórmula:C11H15N5O5Pureza:99.37%Forma y color:SolidPeso molecular:297.27Arg-Gly-Asp-Ser
CAS:Arg-Gly-Asp-Ser (RGDS peptide) is a conserved tetrapeptide sequence found in fibronectin, and the von Willebrand factor.Fórmula:C15H27N7O8Pureza:98.29%Forma y color:SolidPeso molecular:433.42Z62954982
CAS:Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arteriesFórmula:C20H21N3O5SPureza:98.28%Forma y color:SolidPeso molecular:415.46Ref: TM-T37113
1mg35,00€5mg75,00€10mg105,00€25mg173,00€50mg255,00€100mg371,00€200mg530,00€1mL*10mM (DMSO)87,00€2'-Deoxy-2-iodoadenosine
CAS:2'-Deoxy-2-iodoadenosine is a purine nucleoside analog with potential antimicrobial, antioxidant and anti-leukemic activities.Fórmula:C10H12IN5O3Pureza:99.37%Forma y color:SolidPeso molecular:377.14PolQi2
CAS:PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.Fórmula:C21H16ClN5O3SPureza:99.19%Forma y color:SolidPeso molecular:453.9Ref: TM-T84770
1mg84,00€5mg170,00€10mg281,00€25mg542,00€50mg757,00€100mg1.044,00€1mL*10mM (DMSO)195,00€2'-Deoxy-N2-methylguanosine
CAS:2'-Deoxy-N2-methylguanosine is a purine nucleoside analog that can be used as a chemical probe to study DNA-protein interactions.Fórmula:C11H15N5O4Pureza:99.79%Forma y color:SolidPeso molecular:281.27Tenidap
CAS:Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities.Fórmula:C14H9ClN2O3SPureza:98.56% - 99.42%Forma y color:SolidPeso molecular:320.75Levomefolate sodium
CAS:Levomefolate sodium (L-5-MTHF sodium) is a dietary supplement that can be used to study megaloblastic anemia and neurological disorders.Fórmula:C20H23N7Na2O6Pureza:98.7%Forma y color:SolidPeso molecular:503.42MK-5108
CAS:MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.Fórmula:C22H21ClFN3O3SPureza:99.22%Forma y color:SolidPeso molecular:461.94
