Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(94 productos)
- CDK(500 productos)
- Detención del ciclo celular(4 productos)
- Chk(42 productos)
- DYRK(48 productos)
- Dynamin(23 productos)
- Ferroptosis(215 productos)
- HSP(169 productos)
- Integrin(224 productos)
- Kinesina(66 productos)
- LIM quinasa(19 productos)
- Asociado a microtúbulos(261 productos)
- PKC(102 productos)
- PLK(28 productos)
- ROCK(70 productos)
- Rho(2 productos)
- Wee1(15 productos)
- c-Myc(69 productos)
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Se han encontrado 3477 productos de "Ciclo celular / Checkpoint"
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10-Formyl-5,8-dideazafolic acid
CAS:<p>10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor.</p>Fórmula:C22H21N5O7Pureza:96.04%Forma y color:SolidPeso molecular:467.43RSK-IN-1
CAS:<p>RSK-IN-1 (compound 7d) shows anti-tumor activity. RSK-IN-1 is an inhibitor of RSK that inhibits the phosphorylation of YB-1 [1].</p>Fórmula:C22H17NO2Forma y color:SolidPeso molecular:327.38CDK9-IN-15
CAS:<p>CDK9-IN-15: potent CDK9 inhibitor, blocks P-TEFb phosphorylation, inhibits transcription, reduces mRNA, induces tumor cell apoptosis.</p>Fórmula:C16H11N3OSPureza:97.24%Forma y color:SolidPeso molecular:293.34CTP Synthetase-IN-1
CAS:<p>CTP Synthetase-IN-1 is a cytidine 5'-triphosphate synthetase (CTPS) inhibitor with antitumor activity for the study of arthritis and rheumatoid arthritis.</p>Fórmula:C20H19F3N6O3S2Pureza:98.11% - 99.18%Forma y color:SolidPeso molecular:512.53SP-471P
CAS:<p>SP-471P inhibits DENV protease; EC50: DENV1-5.9 μM, DENV2-1.4 μM, DENV3-5.1 μM, DENV4-1.7 μM; CC50 >100 μM; lowers viral RNA synthesis.</p>Fórmula:C33H26BrN5O2Forma y color:SolidPeso molecular:604.515(S)-HpETE
CAS:<p>15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis.</p>Fórmula:C20H32O4Forma y color:SolidPeso molecular:336.47Crisnatol
CAS:<p>Crisnatol (BWA770U) is an oral anticancer DNA intercalator, toxic to breast cancer cells, not skin fibroblasts.</p>Fórmula:C23H23NO2Forma y color:SolidPeso molecular:345.43Cdc7-IN-17
CAS:<p>Cdc7-IN-17 is a potent inhibitor of CDC7 with an IC 50 of <10 μM that can be used in cancer research [1].</p>Fórmula:C13H15N5OSForma y color:SolidPeso molecular:289.36CDK2-IN-13
CAS:<p>CDK2-IN-13: Potent CDK2 inhibitor, arrests cell cycle, induces apoptosis, IC50=12 µM, used in cancer research.</p>Fórmula:C13H12ClN5Forma y color:SoildPeso molecular:273.72CCG-257081
CAS:<p>CCG-257081 blocks Rho/MRTF/SRF pathway; prevents fibrosis in mice; useful in cancer and fibrosis research.</p>Fórmula:C24H19ClF3N3O2Pureza:99.76% - 99.94%Forma y color:SolidPeso molecular:473.87GW8510
CAS:<p>GW8510 is a CDK2 and RRM2 inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 prolongs lifespan.</p>Fórmula:C21H15N5O3S2Pureza:99.32%Forma y color:SolidPeso molecular:449.51CBL 0100 free base
CAS:<p>CBL0100 is an inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation.</p>Fórmula:C24H26N2O2Pureza:98.18% - 98.86%Forma y color:SolidPeso molecular:374.483'-Deoxyuridine-5'-triphosphate
CAS:<p>3'-dUTP, a nucleotide analogue, competitively inhibits RNA polymerases I & II, with a Ki of 2.0 µM.</p>Fórmula:C9H15N2O14P3Forma y color:SolidPeso molecular:468.14CDK8-IN-7
CAS:<p>CDK8-IN-7 is a potent CDK8 inhibitor with a Kd of 3.5 nM, showing promise for AML research.</p>Fórmula:C30H40N2Forma y color:SolidPeso molecular:428.65XVA143
CAS:<p>XVA143, an α/β I-like allosteric antagonist, blocks LFA-1 adhesion and combats P. gingivalis in mice, preventing bone loss.</p>Fórmula:C25H21Cl2N3O8Forma y color:SolidPeso molecular:562.36IDD388
CAS:<p>IDD388 is a selective and potent aldose reductase (ALR2) inhibitor with antitumor activity that inhibits the ALR1 receptor.</p>Fórmula:C16H12BrClFNO4Pureza:99.56%Forma y color:SolidPeso molecular:416.63Laromustine
CAS:<p>Laromustine (VNP40101M) is a sulfonyl hydrolysis alkylation prodrug for cancer treatment with significant anticancer activity, inhibiting thioredoxin reductase.</p>Fórmula:C6H14ClN3O5S2Pureza:≥98%Forma y color:SolidPeso molecular:307.78HBV-IN-4
CAS:<p>HBV-IN-4, a phthalazinone, inhibits HBV DNA replication orally (IC50: 14 nM), encouraging genome-free capsids with strong anti-HBV effects.</p>Fórmula:C24H19ClFN5O3Forma y color:SolidPeso molecular:479.89APC 366
CAS:<p>APC 366: Mast cell tryptase inhibitor, Ki 7.1 μM. Reduces EAR, LAR, BHR in allergic asthma (sheep model).</p>Fórmula:C22H28N6O4Pureza:99.8%Forma y color:SolidPeso molecular:440.5MLAF50
CAS:<p>MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.</p>Fórmula:C15H12I2O4Forma y color:SolidPeso molecular:510.06Cdc7-IN-15
CAS:<p>Cdc7-IN-15 (Example 108) is an inhibitor of cdc7 kinase that has potential to be used for cancer research [1].</p>Fórmula:C12H14N4OSForma y color:SolidPeso molecular:262.33CP681301
CAS:<p>CP681301 is a potent CDK5 inhibitor with anti-tumor effects in Drosophila and reduces Glioma stem cells' growth and renewal.</p>Fórmula:C17H22N4OForma y color:SolidPeso molecular:298.38DNA Gyrase-IN-2
CAS:<p>DNA Gyrase-IN-2 inhibits E. coli (IC50: 3.29-10.49 μM) and M. tuberculosis (IC50: 4.41-5.61 μM) COX, has antibacterial properties.</p>Fórmula:C24H24N8OS2Forma y color:SolidPeso molecular:504.63CDK7-IN-15
CAS:<p>CDK7-IN-15, a pyrimidine-based potent CDK7 inhibitor, shows promise for various cancers with defective transcription.</p>Fórmula:C21H24F4N6OSForma y color:SolidPeso molecular:484.51DHODH-IN-15
CAS:<p>DHODH-IN-15, a hydroxyfuran analogue of A771726, inhibits rat liver DHODH with an IC50 of 11 μM, and is used for rheumatoid arthritis.</p>Fórmula:C15H11N3O3Pureza:99.8%Forma y color:SolidPeso molecular:281.27Beaucage reagent
CAS:<p>Beaucage reagent, which is found to be effective in causing DNA cleavage.</p>Fórmula:C7H4O3S2Pureza:98.50%Forma y color:White To Off-White PowderPeso molecular:200.23WNK1-IN-1
CAS:<p>WNK1-IN-1, a WNK1 inhibitor (IC50: 1.6 μM), also inhibits OSR1 phosphorylation (IC50: 4.3 μM), used in blood pressure and cancer research.</p>Fórmula:C13H15BrCl2N2O4SPureza:98.09%Forma y color:SolidPeso molecular:446.14DNA Gyrase-IN-3
CAS:<p>DNA Gyrase-IN-3 inhibits E. coli DNA gyrase B with IC50 5.41-15.64 μM; shows anti-TB and antibacterial properties.</p>Fórmula:C18H20N6OS2Forma y color:SolidPeso molecular:400.52Valategrast hydrochloride
CAS:<p>Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.</p>Fórmula:C30H33Cl4N3O4Pureza:98%Forma y color:SolidPeso molecular:641.41CH-1504
CAS:<p>CH-1504, dihydrofolate reductase (DHFR) inhibitor, is used potentially for the treatment of rheumatoid arthritis.</p>Fórmula:C23H23N5O5Forma y color:SolidPeso molecular:449.46MMV688844
CAS:<p>MMV688844 inhibits M. abscessus DNA cyclooxygenase (IC50: 2μM) and has MIC50 of 12μM on strain bamboo; useful in antimicrobial studies.</p>Fórmula:C23H25ClN4O2Forma y color:SolidPeso molecular:424.92CDK7-IN-10
CAS:<p>CDK7-IN-10: CDK7 inhibitor, IC50<100 nM, may hinder cell growth, induce apoptosis. (Patent WO2021016388A1, I-1)</p>Fórmula:C29H35N7O3Forma y color:SolidPeso molecular:529.63CDK7-IN-16
CAS:<p>CDK7-IN-16, a potent CDK7 inhibitor (IC50: 1-10 nM), is used in cancer research with transcription defects.</p>Fórmula:C19H21F3N6O2SForma y color:SolidPeso molecular:454.47Y-33075
CAS:<p>Y-33075 (Y-39983 free base) is a ROCK inhibitor that lowers IOP, increases blood flow to ONH, and increases the number of RGCs with regenerating axons.</p>Fórmula:C16H16N4OPureza:98%Forma y color:SolidPeso molecular:280.32DHX9-IN-1
CAS:<p>DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].</p>Fórmula:C21H21F2N5O3SForma y color:SolidPeso molecular:461.49Tripolin A
CAS:<p>Tripolin A is a specific non-ATP competitive inhibitor of Aurora A kinase(Aurora A and Aurora B with IC50 values of 1.5 μM and 7 μM, respectively)</p>Fórmula:C15H11NO3Pureza:98%Forma y color:SolidPeso molecular:253.255-OHdU
CAS:<p>5-OHdU (5-OHdU) is a major oxidation product of 2'-Deoxycytidine and can be incorporated into DNA in vitro.</p>Fórmula:C9H12N2O6Pureza:99.5%Forma y color:SolidPeso molecular:244.2DENV-IN-4
CAS:<p>DENV-IN-4: Effective DENV inhibitor (EC50=4.79 μM), low toxicity (CC50>100 μM), and strong selectivity (SI>20.9); suppresses DENV2 and RdRp.</p>Fórmula:C28H32N4O4SiForma y color:SolidPeso molecular:516.66CDK9-IN-14
CAS:<p>CDK9-IN-14: Potent CDK9 inhibitor, IC50=6.92 nM, effective on MV-4-11 cells and in vivo tumors, low toxicity, minimal side effects.</p>Fórmula:C21H23F2N3O4Forma y color:SolidPeso molecular:419.42ST7612AA1
CAS:<p>ST7612AA1: potent, oral HDAC inhibitor; reactivates HIV-1 latency; shows antitumor effects; may study malaria.</p>Fórmula:C20H27N3O4SPureza:99.71%Forma y color:SolidPeso molecular:405.518-Azido-ADP disodium
CAS:<p>8-Azido-ADP (disodium) is a covalent inhibitor of ADP/ATP exchange in mitochondria, causing irreversible inhibition in light.</p>Fórmula:C10H13N8NaO10P2Forma y color:SolidPeso molecular:490.197Triaziquone
CAS:<p>Triaziquone is an alkylating agent that can react with DNA to form intrastrand crosslinks.</p>Fórmula:C12H13N3O2Forma y color:SolidPeso molecular:231.25FAK/aurora kinase-IN-1
CAS:<p>FAK/aurora kinase-IN-1, a dual inhibitor of FAK and aurora kinase, has IC50 values of 6.61 nM and 0.91 nM respectively, and demonstrates anticancer effects (WO2018019252A1; compound 11) [1].</p>Fórmula:C23H24ClN7O3Forma y color:SolidPeso molecular:481.93tBID
CAS:<p>tBID is a selective homeodomain-interacting protein kinase 2 (HIPK2) inhibitor (IC50 of 0.33 μM)</p>Fórmula:C11H3Br4N3O2Pureza:98%Forma y color:SolidPeso molecular:528.78P18IN003
CAS:<p>P18IN003 is a selective and effective p18(INK4C) inhibitor that inhibits the activity of p18 protein and can be used to study in vitro expansion of</p>Fórmula:C17H16N2O3Pureza:98.77%Forma y color:SolidPeso molecular:296.32Cdc7-IN-3
CAS:<p>Cdc7-IN-3 is a potent inhibitor of Cdc7 kinase.</p>Fórmula:C20H22N4O5Pureza:98%Forma y color:SolidPeso molecular:398.41LCAHA
CAS:<p>LCAHA is a USP2a inhibitor. LCAHA inhibits growth of cyclin D1-dependent cells.</p>Fórmula:C24H41NO3Forma y color:SolidPeso molecular:391.59Flurocitabine
CAS:<p>Flurocitabine is a therapeutic agent with antineoplastic activity.</p>Fórmula:C9H10FN3O4Pureza:98%Forma y color:SolidPeso molecular:243.19DHFR-IN-5
CAS:<p>DHFR-IN-5: potent, oral DHFR inhibitor, Ki 0.54 nM against mutant P. falciparum, anti-malarial.</p>Fórmula:C18H24N4O4Forma y color:SolidPeso molecular:360.41FN-1501-propionic acid
CAS:<p>FN-1501-propionic acid, a CDK2/9 ligand, in conjunction with a CRBN ligand, has been utilized in the design of a PROTAC CDK2/9 degrader.</p>Fórmula:C25H27N9O4Pureza:98%Forma y color:SolidPeso molecular:517.54Zelpolib
CAS:<p>Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.</p>Fórmula:C22H21N3O5S2Pureza:98.79%Forma y color:SolidPeso molecular:471.5510-Methyl-10-deazaaminopterin
CAS:<p>10-Methyl-10-deazaaminopterin is a folate analog that shows antitumor activity.</p>Fórmula:C21H23N7O5Pureza:98%Forma y color:SolidPeso molecular:453.45N2-Ethylguanosine
CAS:<p>N2-Ethylguanosine is a Nucleoside Derivative - 2-Modified purine nucleoside.</p>Fórmula:C12H17N5O5Forma y color:SolidPeso molecular:311.29Y-9738
CAS:<p>Y-9738 is an agent of hypolipidemic.</p>Fórmula:C15H16ClNO4Pureza:98%Forma y color:SolidPeso molecular:309.74NSC 693868
CAS:<p>CDKs and GSK-3 inhibitor</p>Fórmula:C9H7N5Pureza:98%Forma y color:SolidPeso molecular:185.19Zaurategrast ethyl ester sulfate
CAS:<p>Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders.</p>Fórmula:C56H60Br2N8O10SPureza:98%Forma y color:SolidPeso molecular:1197.01HBV-IN-22
CAS:<p>HBV-IN-22 (Compound LC5f) is an HBV DNA replication inhibitor that acts on both wild-type HBV (IC50: 0.71 μM) and drug-resistant HBV (IC50: 0.84 μM).</p>Fórmula:C26H29N3O2S2Forma y color:SolidPeso molecular:479.66NSC666715
CAS:<p>NSC666715 is the strand-displacement activity of DNA polymerase inhibitor.</p>Fórmula:C15H13Cl2N5O2S2Pureza:98%Forma y color:SolidPeso molecular:430.33ROCK2-IN-5
<p>ROCK2-IN-5, a compound blending fasudil, caffeic, and ferulic acids, shows promise for ALS research involving SOD1 mutations.</p>Fórmula:C23H25N3O5SForma y color:SolidPeso molecular:455.53S-(N-PhenethylthiocarbaMoyl)-L-cysteine
CAS:<p>PEITC-Cys: anticarcinogenic, antileukemic, inhibits DNA synthesis in HL60, P450 inhibitor.</p>Fórmula:C12H16N2O2S2Forma y color:SolidPeso molecular:284.4Aurora A/PKC-IN-1
CAS:<p>Aurora A/PKC-IN-1 inhibits AurA (IC50: 6.9 nM), PKCα (IC50: 16.9 nM), and hinders breast cancer cell growth and spread.</p>Fórmula:C16H14N6OSe2Forma y color:SolidPeso molecular:464.24KIRA-7
CAS:<p>KIRA-7: imidazopyrazine, anti-fibrotic, inhibits IRE1α RNase (IC50: 110 nM) allosterically.</p>Fórmula:C27H23FN6OForma y color:SolidPeso molecular:466.51DHODH-IN-1
CAS:<p>DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.</p>Fórmula:C21H20F3N3O2Pureza:99.76%Forma y color:SolidPeso molecular:403.4BRD9185
CAS:<p>BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.</p>Fórmula:C23H21F6N3O2Pureza:98%Forma y color:SolidPeso molecular:485.42Zaurategrast ethyl ester
CAS:<p>Zaurategrast ethyl ester, an α4β1/α4β7 integrin antagonist prodrug of CT7758, treats inflammatory/autoimmune conditions.</p>Fórmula:C28H29BrN4O3Pureza:98%Forma y color:SolidPeso molecular:549.46DHFR-IN-2
CAS:<p>DHFR-IN-2 (4e) is a potent MtDHFR uncompetitive inhibitor with a 7 μM IC50, promising for TB research.</p>Fórmula:C14H13NO2Forma y color:SolidPeso molecular:227.26(E/Z)-BIO-acetoxime
CAS:<p>(E/Z)-BIO-acetoxime: potent GSK-3 α/β inhibitor; IC50: GSK-3α/β 10nM, CDK5/p25 2.4μM, CDK2/A 4.3μM, CDK1/B 63μM.</p>Fórmula:C18H12BrN3O3Forma y color:SolidPeso molecular:398.21Capzimin
CAS:<p>Capzimin is a selective inhibitor of proteasome isopeptidase Rpn11.</p>Fórmula:C30H24N6O2S4Pureza:98.31% - 99.32%Forma y color:SolidPeso molecular:628.818-Deazahomofolic acid
CAS:<p>8-Deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor and other folate related enzymes inhibitor.</p>Fórmula:C21H22N6O6Pureza:98%Forma y color:SolidPeso molecular:454.44A 65281
CAS:<p>A 65281: antibacterial isothiazoloquinolone, inhibits P4-unknotting, induces DNA breakage via topoisomerase II.</p>Fórmula:C17H16F2N4O2SPureza:98%Forma y color:SolidPeso molecular:378.4MFH290
CAS:<p>MFH290 is a selective CDK12/13 inhibitor, covalently bonding with CDK12 Cys-1039, blocks Pol II CTD phosphorylation, and enhances olaparib's efficacy.</p>Fórmula:C26H31N5O3S2Forma y color:SolidPeso molecular:525.69RHI002-Me
CAS:<p>RHI002-Me is a methylated derivative of RHI002, a selective inhibitor of human RNaseH2.</p>Fórmula:C18H19N3O2S2Pureza:98%Forma y color:SolidPeso molecular:373.49Direct Black 38 free acid
CAS:<p>Ferristatin II (Direct Black 38 free acid) is a polysulphonated dye and promotes the degradation of transferrin receptor-1 in vitro and in vivo.</p>Fórmula:C34H27N9O7S2Pureza:98%Forma y color:SolidPeso molecular:737.77ROCK-IN-D2
CAS:<p>ROCK-IN-D2 is an effective and selective inhibitor of ROCK.</p>Fórmula:C22H28N6OPureza:98%Forma y color:SolidPeso molecular:392.5Atuveciclib S-Enantiomer
CAS:<p>Atuveciclib S-Enantiomer is a (S)-form of BAY-1143572; a potent, selective CDK9 inhibitor with an IC50 of 16 nM.</p>Fórmula:C18H18FN5O2SPureza:98%Forma y color:SolidPeso molecular:387.43RET-IN-19
CAS:<p>RET-IN-19, a potent RET inhibitor, anticancer: IC50 6.8 nM (RET-wt), 13.51 nM (RET V804M); for NSCLC research.</p>Fórmula:C28H28N6O4SForma y color:SolidPeso molecular:544.62(R)-Filanesib
CAS:<p>(R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM).</p>Fórmula:C20H22F2N4O2SForma y color:SolidPeso molecular:420.48Apricitabine
CAS:<p>Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-</p>Fórmula:C8H11N3O3SPureza:99.45%Forma y color:SolidPeso molecular:229.26PD 130883
CAS:<p>PD 130883 is a potent lipophilic quinazoline antifolate.</p>Fórmula:C18H15N5O3Pureza:98%Forma y color:SolidPeso molecular:349.34RP-106
CAS:<p>RP-106 is an ATP-competitive inhibitor of CDK5/p25, CDK1/cyclin B, and GSK-3.</p>Fórmula:C17H19N3OPureza:98%Forma y color:SolidPeso molecular:281.35A 65282
CAS:<p>A 65282: antibacterial isothiazoloquinolone, inhibits P4-unknotting, causes DNA breaks via topoisomerase II.</p>Fórmula:C17H16F2N4O2SPureza:98%Forma y color:SolidPeso molecular:378.4CDK8-IN-10
CAS:<p>CDK8-IN-10 is a selective and potent inhibitor of cell cycle protein-dependent kinase (CDK8) (IC50: 8.25 nM) that can be used to study cancer.</p>Fórmula:C25H15ClF3N5O3Forma y color:SolidPeso molecular:525.87CDK4/6-IN-8
CAS:<p>CDK4/6-IN-8 (Compound 7p) is a selective inhibitor of CDK4 (IC50=5.01 nM) and CDK6 (IC50=3.97 nM).</p>Fórmula:C18H18N6O5Forma y color:SolidPeso molecular:398.37IMB-10
CAS:<p>IMB-10 is an alphaMbeta2 integrin modulator, inhibiting leukocyte migration and recruitment in vitro and in vivo.</p>Fórmula:C19H15NOS2Forma y color:SolidPeso molecular:337.46CRT5
CAS:<p>CRT5, a selective PKD inhibitor, blocks VEGF effects on histone deacetylase 5, CREB, HSP27, and endothelial functions. IC50s: 1-2 nM for PKD1-3.</p>Fórmula:C28H30N4O2Forma y color:SolidPeso molecular:454.56AnnH31
CAS:<p>AnnH31 is a potent Dyrk1A inhibitor with an IC50 value of 81 nM.AnnH31 inhibits MAO-A with an IC50 of 3.2 μM.AnnH31 can be used as a probe to confirm the</p>Fórmula:C15H13N3OPureza:99.88%Forma y color:SolidPeso molecular:251.28hDHODH-IN-4
CAS:<p>hDHODH-IN-4, a potent DHODH inhibitor, has a pIC50 of 7.8 and blocks measles virus replication with a pMIC50 of 8.8.</p>Fórmula:C21H24N4O2Pureza:99.87%Forma y color:SolidPeso molecular:364.44SC-203885
CAS:<p>SC-203885 is a checkpoint kinase 2 inhibitor.</p>Fórmula:C15H13N5O2Pureza:98%Forma y color:SolidPeso molecular:295.3DHODH-IN-24
CAS:<p>DHODH-IN-24 (compound 16) serves as a powerful inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 91 nM [1].</p>Fórmula:C26H26N4Forma y color:SolidPeso molecular:394.51Kira8 Hydrochloride
CAS:<p>Kira8 Hydrochloride is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.</p>Fórmula:C31H30Cl2N6O3SPureza:98%Forma y color:SolidPeso molecular:637.58Clociguanil
CAS:<p>Clociguanil has antimalarial activity.</p>Fórmula:C12H15Cl2N5OForma y color:SolidPeso molecular:316.19CDK4/6-IN-12
CAS:<p>CDK4/6-IN-12 inhibits CDK4/6 with IC50s of 592.3 nM & 3090 nM, useful in cancer research.</p>Fórmula:C12H10N6Forma y color:SolidPeso molecular:238.25Tenofovir exalidex
CAS:<p>Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant</p>Fórmula:C28H52N5O5PPureza:99.83%Forma y color:SolidPeso molecular:569.72BPIC
CAS:<p>BPIC is an agent of anti-tumor that acts by inhibiting inflammation and scavenging free radicals.</p>Fórmula:C27H20N2O5Forma y color:SolidPeso molecular:452.46Levofloxacin sodium
CAS:<p>Levofloxacin sodium: synthetic antibacterial, stops DNA replication by inhibiting bacterial DNA gyrase.</p>Fórmula:C18H20FN3NaO4Pureza:98%Forma y color:SolidPeso molecular:384.363FRα-IN-1
CAS:<p>FRα-IN-1 (Compound 4) is a tumour targeting agent. FRα-IN-1 exhibits selective anti-cancer effects on FRα and FRβ expressing cells.</p>Fórmula:C21H24N6O6Forma y color:SolidPeso molecular:456.45CLK1-IN-2
<p>CLK1-IN-2: Metabolically stable, Clk1-selective inhibitor; IC50=1.7nM; useful in tumor, Duchenne MD, HIV-1, influenza research.</p>Fórmula:C16H12Cl2N2O2SForma y color:SolidPeso molecular:367.25TDRL-X80
CAS:<p>TDRL-X80 inhibits XPA DNA binding; effective on single, double, and cisplatin-damaged DNA; IC50: 18-29 μM (FP), 21-39 μM (ELISA).</p>Fórmula:C23H15ClN2O6Forma y color:SolidPeso molecular:450.83Metioprim
CAS:<p>Metioprim is a competitive bacterial dihydrofolate reductases inhibitor.</p>Fórmula:C14H18N4O2SPureza:98%Forma y color:SolidPeso molecular:306.38XL-188
CAS:<p>XL-188: Potent, selective USP7 inhibitor, IC50 = 193 nM (domain), 90 nM (full). Boosts p53, p21; degrades HDM2. Unique among DUB inhibitors.</p>Fórmula:C32H42N6O4Forma y color:SolidPeso molecular:574.71
