Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(114 productos)
- CDK(546 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(226 productos)
- HSP(179 productos)
- Integrin(253 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(274 productos)
- PKC(124 productos)
- PLK(25 productos)
- ROCK(62 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
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Se han encontrado 3872 productos de "Ciclo celular / Checkpoint"
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NUAK1-IN-1
NUAK1-IN-1 (Compound 9) is an inhibitor of NUAK1 with an IC50 of 5.012 nM, as well as a CDK4 inhibitor. It is suitable for research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.Fórmula:C25H30N6OForma y color:SolidPeso molecular:430.545(Gly0.8Nap0.2)20
(Gly0.8Nap0.2)20 is a dual-target compound effective against fungal membranes and DNA. It exhibits antimicrobial properties.Fórmula:C139H236N38O24·16(C2F3O2)2'-O-(2-Methoxyethyl)guanosine 5'-triphosphate ammonium
2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate (ammonium), a purine nucleoside analog, exhibits extensive antitumor properties, particularly against indolentFórmula:C13H34N9O15P3Forma y color:SolidPeso molecular:649.38CDK-IN-12
CAS:CDK-IN-12 (Example 20), a CDK inhibitor, effectively inhibits CDK4/6, demonstrating IC50 values below 20 nM [1].Fórmula:C26H29FN6OSForma y color:SolidPeso molecular:492.61RA-V
RA-V is a natural product that can be used as a reference standard.Fórmula:C160H202N24O41Forma y color:SolidPeso molecular:3117.5AR-13324 analog mesylate
AR-13324 analog mesylate is an inhibitor of Rho-kinase and a norepinephrine transporter and reduces intraocular pressure in normotensive monkey eyes.Fórmula:C29H33N3O9S2Pureza:98%Forma y color:SolidPeso molecular:631.72Cytarabine triphosphate
CAS:Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.Fórmula:C9H16N3O14P3Forma y color:SolidPeso molecular:483.165'-ODMT cEt G Phosphoramidite (Amidite)
CAS:5'-ODMT cEt G Amidite is a safe, effective nucleic acid analog with strong antisense activity.Fórmula:C46H56N7O9PForma y color:SolidPeso molecular:881.95USP7-IN-16
CAS:USP7-IN-16 (Compound 61) is a selective inhibitor of USP7, with IC50 values of 5.5 nM in the FLINT assay and 2.1 nM in MM.1S cells. This compound exhibits antitumor activity in mice and holds potential for research in the field of oncology.Fórmula:C43H45N7O6SForma y color:SolidPeso molecular:787.93DSPE-PEG2000-cRGD
DSPE-PEG2000-cRGD is a PEG compound composed of DSPE and an αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. This compound can be utilized for drug delivery.Forma y color:Odour Solidm7GpppUmpG
CAS:m7GpppUmpG, a trinucleotide cap analogue, enables RNA synthesis with cap 0 or 1 structures.Fórmula:C31H42N12O26P4Forma y color:SolidPeso molecular:1122.63huATN-658
huATN-658 (MNPR-101) is a humanized monoclonal antibody inhibitor targeting the urokinase-type plasminogen activator receptor (uPAR). It effectively disrupts the interaction between uPAR and integrins, thereby inhibiting tumor cell proliferation, invasion, and migration. huATN-658 shows potential for research in breast cancer, particularly in cases of triple-negative breast cancer.Forma y color:Odour LiquidNusinersen
CAS:Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.Pureza:98.62%Forma y color:SolidMaleuric acid
CAS:Maleuric acid is an anti-mitotic agent for research and boosts growth and fertility in flora and fauna.
Fórmula:C5H6N2O4Pureza:98.92%Forma y color:SolidPeso molecular:158.11PLK1-IN-2
CAS:PLK1-IN-2 is a PLK1 kinase inhibitor with an IC 50 value of 0.384 μM.Fórmula:C24H27FN8OSForma y color:SolidPeso molecular:494.59Orotidine 5′-monophosphate trisodium
CAS:Orotidine 5'-monophosphate trisodium, a pyrimidine nucleotide, is synthesized through the de novo DNA synthesis pathway by various microorganisms, including M.Fórmula:C10H10N2Na3O11PForma y color:SolidPeso molecular:434.14N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-5-methyl-2'-deoxycytidine
N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-5-methyl-2’-deoxycytidine, a purine nucleoside analog, exhibits broad antitumor activity particularly against indolentFórmula:C33H35N3O7Forma y color:SolidPeso molecular:585.65HDAC-IN-85
HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.Fórmula:C24H27FN4O5Forma y color:SolidPeso molecular:470.49N3-(2S)-[2-(tert-Butoxycarbonyl)amino-3-(tert-butoxy carbonyl)]propyluridine
N3-(2S)-propyluridine is a uridine analog with potential as an antiepileptic and for antihypertensive agent research.Fórmula:C22H35N3O10Forma y color:SolidPeso molecular:501.533'-β-C-Methyl-N6-isopentenyl adenosine
3’-Beta-C-Methyl-N6-isopentenyl adenosine is an adenosine analog.Fórmula:C16H23N5O4Forma y color:SolidPeso molecular:349.38CDK7-IN-7
CAS:CDK7-IN-7: Selective CDK7 inhibitor, IC50 < 50 nM (Patent CN112661745A).Fórmula:C20H20BrF3N6O2Forma y color:SolidPeso molecular:513.319IBU-DC Phosphoramidite
CAS:IBU-DC Phosphoramidite is used for synthesis of oligonucleotides.Fórmula:C43H54N5O8PForma y color:SolidPeso molecular:799.906IRE1α kinase-IN-6
CAS:IRE1α kinase-IN-6 is a potent IRE1α inhibitor with an IC 50 value of 4.4 nM.Fórmula:C25H23Cl2FN6O3S2Forma y color:SolidPeso molecular:609.52Cytidine 5'-diphosphate trisodium salt
CAS:CDP, a trisodium salt, helps synthesize DNA/RNA by aiding phosphoryl transfer from ATP to CMP via UMPK.Fórmula:C9H15N3Na3O11P2Pureza:99.55%Forma y color:White Crystalline PowderPeso molecular:472.157-Deazaxanthine
CAS:7-Deazaxanthine (7DX) is an inhibitor of thymidine phosphorylase (TPase) and reduces TPase activity in a concentration-dependent manner, with an IC50 value of 40 μM. Additionally, 7-Deazaxanthine exhibits significant anti-angiogenic properties.Fórmula:C6H5N3O2Forma y color:SolidPeso molecular:151.12Centaureidin
CAS:Centaureidin is a useful organic compound for research related to life sciences. The catalog number is T125588 and the CAS number is 17313-52-9.Fórmula:C18H16O8Forma y color:SolidPeso molecular:360.318N1-Methyl-2'-β-C-methyl inosine
N1-Methyl-2’-beta-C-methyl inosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies through mechanisms thatFórmula:C12H16N4O5Forma y color:SolidPeso molecular:296.28Suricapavir
CAS:Suricapavir is an effective viral replication inhibitor with antiviral activity.Fórmula:C41H29ClF9N9O4SForma y color:SolidPeso molecular:950.23CCT241533 dihydrochloride
CAS:Potent Chk2 inhibitor with 3 nM IC50, 63-fold more selective over Chk1, affects 84 kinases, reduces DNA damage response and apoptosis in cells.Fórmula:C23H29Cl2FN4O4Forma y color:SolidPeso molecular:515.41Uridine triphosphate 13C9,15N2 sodium
CAS:Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.Fórmula:C9H1415N2NaO15P3Forma y color:SolidPeso molecular:517.04PROTAC MPS1 degrader 1
PROTAC MPS1 degrader 1 (Compound 19) acts as a potent degrader of Monopolar spindle 1 (Mps1, TTK), AURKA, and AURKB, with DC50 values of 17.7, 108.7, and 570.3 nM respectively. It is utilized in the study of acute myeloid leukemia. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligase)Fórmula:C41H46N12O7Forma y color:SolidPeso molecular:818.88αvβ5 integrin-IN-1
CAS:αvβ5 integrin-IN-1, a potent and selective αvβ5 integrin inhibitor, exhibits a high inhibitory potency with a pIC50 value of 8.2.Fórmula:C25H28F3N3O3Forma y color:SolidPeso molecular:475.512SR15006
CAS:SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).Fórmula:C16H20ClN3O4SPureza:99.87%Forma y color:SoildPeso molecular:385.872'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
CAS:dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.Fórmula:C10H14N5Na2O8PForma y color:SolidPeso molecular:409.202DSPE-PEG1000-cRGD
DSPE-PEG1000-cRGD is a PEG compound composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to the αvβ3 receptors present on the surfaces of various cancer cells and angiogenic vascular cells. DSPE-PEG1000-cRGD is applicable in drug delivery.Forma y color:Odour SolidCDK9-IN-25
CDK9-IN-25 (compound 4a), an imidazopyrazine derivative, functions as a CDK9 inhibitor with an IC50 of 0.24 μM.Fórmula:C15H16FN5Pureza:98%Forma y color:SolidPeso molecular:285.32Activated Protein C (390-404), human TFA
APC's 390-404 peptide region key to anticoagulation, binds antibodies/proteins, inactivates cofactors Va/VIIIa.Fórmula:C93H131F3N22O25Pureza:98%Forma y color:SolidPeso molecular:2014.16Ibezapolstat hydrochloride
CAS:Ibezapolstat hydrochloride is an antibacterial agent.Fórmula:C18H21Cl3N6O2Pureza:99.84%Forma y color:SoildPeso molecular:459.756Ref: TM-T60171
1mg109,00€2mg163,00€5mg241,00€10mg355,00€25mg532,00€50mg745,00€100mg1.018,00€500mgA consultar1mL*10mM (DMSO)284,00€VPC-18005
CAS:VPC-18005: a luciferase inhibitor that blocks ERG-induced transcription by binding ERG-ETS, hindering DNA attachment.
Fórmula:C15H17N3O3SPureza:99.95%Forma y color:SoildPeso molecular:319.38Cyclopentyluracil
CAS:Cyclopentyluracil is a carbocyclic analogue of uridine.Fórmula:C10H14N2O5Pureza:98%Forma y color:SolidPeso molecular:242.23N1-(2-Methyl)propyl pseudouridine
N1-(2-Methyl)propyl pseudouridine, a purine analog, targets lymphoid cancer by inhibiting DNA synthesis and inducing apoptosis.Fórmula:C13H20N2O6Forma y color:SolidPeso molecular:300.31Erythromycin A dihydrate
CAS:Erythromycin dihydrate, a macrolide antibiotic from Streptomyces erythreus, targets 50S ribosomal subunits, blocking protein synthesis.Fórmula:C37H69NO14Forma y color:SolidPeso molecular:751.94m7GpppCpG
CAS:m7GpppCpG, a trinucleotide cap analogue, is used for synthesizing RNA with cap 0 or cap 1 structures.Fórmula:C30H41N13O25P4Forma y color:SolidPeso molecular:1107.61wrwycr-NH2 TFA
wrwycr-NH2 (TFA) is a peptide that exhibits cytotoxic properties against various cancer cells, inducing DNA damage and cell cycle arrest without causing endoplasmic reticulum stress. It possesses antitumor activity, and its efficacy is enhanced when used in combination with DNA-damaging agents.Forma y color:Odour SolidXY028-133
CAS:XY028-133 is a PROTAC-based CDK4/6 degrader for the study of tumors.
Fórmula:C53H67N11O7SPureza:97.11%Forma y color:SolidPeso molecular:1002.23Biotin-PEG8-Vidarabine
Biotin-PEG8-Vidarabine is an antiviral PEG linker targeting herpes and varicella zoster with adenosine analog Vidarabine.Fórmula:C36H60N8O13SForma y color:SolidPeso molecular:844.975'-O-DMT-ibu-dC
CAS:5'-O-DMT-ibu-dC can be used in the synthesis of oligodeoxyribonucleotides.Fórmula:C34H37N3O7Forma y color:SolidPeso molecular:599.67Nogalamycin
CAS:Nogalamycin is an anthracycline antibiotic with antitumor properties produced by soil bacteria Streptomyces nogalater.Fórmula:C39H49NO16Pureza:98%Forma y color:SolidPeso molecular:787.8125'-O-DMT-2'-O-TBDMS-Ac-rC
CAS:5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.Fórmula:C38H47N3O8SiForma y color:SolidPeso molecular:701.892Rachelmycin
CAS:Rachelmycin, a potent antibiotic and antitumor agent from Streptomyces zelensis, binds to DNA's minor groove.Fórmula:C37H33N7O8Forma y color:SolidPeso molecular:703.712PROTAC CDK9 degrader-7
CAS:PROTAC CDK9 degrader-7 is a proteolysis-targeting chimera (PROTAC) specifically designed to target and mediate the degradation of Cyclin-Dependent Kinase 9 (Fórmula:C43H50Cl2N8O9Forma y color:SoildPeso molecular:893.81Fibronectin CS1 Peptide
CAS:Fibronectin CS1 peptide inhibits tumor metastasis, lacking RGD domain; may aid cancer therapy.Fórmula:C38H64N8O15Pureza:98%Forma y color:SolidPeso molecular:872.96N6-Methyl-2'-O-(2-methoxyethyl) adenosine
N6-Methyl-2’-O-(2-methoxyethyl) adenosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Fórmula:C14H21N5O5Forma y color:SolidPeso molecular:339.35KIF18A-IN-12
CAS:KIF18A-IN-12 (compound 9), a potent KIF18A inhibitor, exhibits an IC 50 of 45.54 nM and is utilized in cancer research.Fórmula:C30H39F2N5O4SForma y color:SolidPeso molecular:603.72Cotylenin A
CAS:Cotylenin A is a phenanthraquinone compound that synergistically works with vitamin K2 to induce monocyte differentiation and growth arrest. It also inhibits c-Myc expression while inducing cyclin G2 expression in human leukemia HL-60 cells. Cotylenin A is applicable in acute myeloid leukemia research.Fórmula:C33H50O11Forma y color:SolidPeso molecular:622.7442'-Fluoro-2'-deoxy-arabinoadenosine 5'-triphosphate triethylamine
2’-Fluoro-2’-deoxy-arabinoadenosine 5’-triphosphate (triethylamine) is a purine nucleoside analog with significant antitumor properties, particularly effectiveFórmula:C34H75FN9O12P3Forma y color:SolidPeso molecular:913.93Emofolin sodium
CAS:Emofolin sodium, a synthetic folate analogue, inhibits DNA/RNA/protein synthesis by blocking dihydrofolate reductase.Fórmula:C21H25N7Na2O6Pureza:98%Forma y color:SolidPeso molecular:517.45MYC-IN-2
CAS:MYC-IN-2 is a protein-protein inhibitor targeting the MYC protein, designed for use in cancer research.Fórmula:C25H17N3O2SForma y color:SolidPeso molecular:423.49Agrocin 84
CAS:Agrocin 84 is a microbial metabolite that inhibits DNA and protein synthesis, as well as amino acid transport, in the susceptible and virulent Agrobacterium strain H-38-9.Fórmula:C22H36N6O16P2Forma y color:SolidPeso molecular:702.4992',3'-Dideoxyuridine-5'-O-(1-thiotriphosphate) tetrasodium
2',3'-Dideoxyuridine-5'-O-(1-thiotriphosphate) (ddUTPαS) tetrasodium is a sulfur-containing nucleoside triphosphate derivative.Forma y color:Odour Solid[pSer2, pSer5, pSer7]-CTD TFA
Substrate '[pSer2, pSer5, pSer7]-CTD (TFA)' for CDK7 phosphorylates RNA Pol II CTD at ser2, 5, 7.Fórmula:C98H138F3N21O39Pureza:98%Forma y color:SolidPeso molecular:2291.25Polynucleotide kinase
CAS:Polynucleotide Kinase is a DNA repair enzyme. It exhibits 5'-kinase activity by catalyzing the transfer of phosphate from ATP to the 5'-hydroxyl (OH) end, and also shows 3'-phosphatase activity by converting the 3'-phosphate end into a 3'-OH end.Pyrindamycin A
CAS:Pyrindamycin A is an antibiotic that inhibits DNA synthesis,and shows antitumor activities against murine leukemia.Fórmula:C26H26ClN3O8Pureza:98%Forma y color:SolidPeso molecular:543.95H122
H122 is a TEADPROTAC degrader effective in degrading TEAD1 with a DC50 of 3 nM, and it shows strong affinity for TEAD2, TEAD3, and TEAD4 with Ki values of 2.0, 3.6, and 1.6 nM, respectively. H122 also downregulates Myc expression and inhibits the growth of MSTO-211H and NCI-H226 cells, with IC50 values of 21.3 nM and 0.6 nM, respectively, demonstrating antitumor activity in mouse models. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligaseCereblon)Fórmula:C45H45ClFN5O8Forma y color:SolidPeso molecular:838.3191-(β-D-Xylofuranosyl)-N6-(m-methoxybenzyl)adenine
1-(β-D-Xylofuranosyl)-N6-(m-methoxybenzyl)adenine is an adenosine analog.Fórmula:C18H21N5O5Forma y color:SolidPeso molecular:387.39N1-Methylpseudouridine-5′-triphosphate tetralithium
N1-Methylpseudouridine-5′-triphosphate tetralithium, also known as 1-Methylpseudouridine-5′-triphosphate tetralithium, is a nucleobase-modified nucleotide.Fórmula:C10H13Li4N2O15P3Forma y color:SolidPeso molecular:521.9FRα-targeting peptide C7 TFA
FRα-targeting peptide C7 TFA is a selective peptide ligand for the folate receptor alpha (FRα) that specifically binds to FRα-expressing cells and has tumor-targeting capabilities in vivo. It is applicable in research related to tumor diagnosis and therapy.Forma y color:Odour Solid3'-β-C-Methyl-2-thiouridine
3’-β-C-Methyl-2-thiouridine, a purine nucleoside analog, exhibits extensive antitumor activity, particularly against indolent lymphoid malignancies.Fórmula:C10H14N2O5SForma y color:SolidPeso molecular:274.295-Aza-xylo-cytidine
5-Aza-xylo-cytidine, a purine analog with antitumor effects, inhibits DNA synthesis and induces apoptosis in lymphoid cancers.Fórmula:C8H12N4O5Forma y color:SolidPeso molecular:244.2N3-[(Pyrid-4-yl)methyl]uridine
N3-[(Pyrid-4-yl)methyl]uridine, a uridine analog, may have antiepileptic properties and aid in researching anticonvulsants and anxiolytics.Fórmula:C15H17N3O6Forma y color:SolidPeso molecular:335.31RNA polymerase II-IN-2
RNA Pol II-IN-2 (20iii) strongly inhibits Pol II (Ki=9.5 nM), is more toxic to CHO/HEK293 than α-amanitin.Fórmula:C41H58N10O12SForma y color:SolidPeso molecular:915.022'-Chloro-N6-(3-trifluoromethyl)benzyl adenosine
2’-Chloro-N6-(3-trifluoromethyl)benzyl adenosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoidFórmula:C18H17ClF3N5O4Forma y color:SolidPeso molecular:459.81SNX7
CAS:SNX7 (WAY-323879) inhibits CDKI pathway; useful for studying aging and related diseases.Fórmula:C15H14N2OPureza:99.96%Forma y color:SolidPeso molecular:238.28LL-K8-22
LL-K8-22: potent CDK8/cyclin C degrader; DC50 ~2.5μM; hinders STAT1 phosphorylation; curbs E2F/MYC cancer pathways; for TNBC study.Fórmula:C37H43N5OForma y color:SolidPeso molecular:573.77ddTTPαS tetrasodium
ddTTPαS tetrasodium is a sulfur-containing nucleotide triphosphate derivative used in chain extension during PCR assays.Forma y color:Odour SolidCarbazole
CAS:Carbazole belongs to the class of carbazole-based organic compounds. Carbazole can form novel DNA small groove complexes, inhibiting the synthesis of new DNA or RNA.Fórmula:C12H9NPureza:99.82%Forma y color:SolidPeso molecular:167.2112'-Amino-2'deoxyadenosine-5'-O-diphosphate sodium
2'-Amino-2'-deoxyadenosine-5'-O-diphosphate (2'-NH2-ADP) sodium is an amine-modified nucleotide, serving as a structural analog of the purine nucleotide ADP.Forma y color:Odour SolidBSJ-04-132
Selective Cdk4 degrader. Degrades Cdk4 in Molt-4 cells, with no effect on Cdk6 levels. Displays cereblon-dependent degradation.Forma y color:LiquidPurine riboside-5'-O-triphosphate sodium
CAS:Purine riboside-5'-O-triphosphate sodium is an active metabolite of Nebularine and acts as an inhibitor of DNA primase ATP and GTP polymerization activities, with IC50 values of 35 µM and 28 µM, respectively. It also inhibits calmodulin-dependent protein kinase II (CaMKII), with a Ki value of 590 µM.Fórmula:C10H11N4Na4O13P3Forma y color:SolidPeso molecular:580.09CDK8/19-IN-3
CDK8/19-IN-3 (compound 3-7) is a potent and selective inhibitor of CDK8 and CDK19. It can increase IL-10 levels and has potential for research in inflammatory bowel disease (IBD).Fórmula:C20H23FN6O2Forma y color:SolidPeso molecular:398.4346-Methoxypurine-9-β-D-(3-methoxy riboside)
6-Methoxypurine riboside is a purine analog with anti-lymphoma activity via DNA synthesis inhibition and apoptosis induction.Fórmula:C12H16N4O5Forma y color:SolidPeso molecular:296.286-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
6-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a purine nucleoside analogue with broad antitumor activity, particularly againstFórmula:C10H15N7O4Forma y color:SolidPeso molecular:297.27Py-MAA-Val-Cit-PAB-DX8951
CAS:Py-MAA-Val-Cit-PAB-DX8951, a purine toxin, serves as an intermediate in the synthesis of antibody-drug conjugates [1].Fórmula:C57H66FN11O13SForma y color:SolidPeso molecular:1164.26CPS2
CAS:CPS2: potent, selective PROTAC CDK2 degrader. IC50=24nM, targets acute myeloid leukemia research.Fórmula:C38H42N12O10S2Forma y color:SolidPeso molecular:890.94PDI-IN-4
PDI-IN-4 (Compound 14d) is a protein disulfide isomerase inhibitor with an IC50 value of 0.48 μM. It prevents platelet aggregation and thrombosis by reducing the activation of GPIIb/IIIa, without causing significant cytotoxicity. PDI-IN-4 is applicable in thrombosis research.Fórmula:C17H12F3NO2Forma y color:SolidPeso molecular:319.278Rev 2'-O-MOE-C(Bz)-5'-amidite
'Rev 2’-O-MOE-C(Bz)-5’-amidite, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.Fórmula:C49H58N5O10PForma y color:SolidPeso molecular:907.99CDP-β-S trisodium salt
CDP-β-S (Cytidine-5'-O-(2-thiodiphosphate)) trisodium salt is a non-hydrolyzable analog of CDP (Cytidine Diphosphate) with antioxidant and free radical scavenging properties.Forma y color:Odour SolidZIKV-IN-6
ZIKV-IN-6 (compound 22) acts as a direct inhibitor of the Zika virus (ZIKV) by binding to its RNA-dependent RNA polymerase (RdRp) and obstructing viral RNAForma y color:Odour SolidGuanosine 5'-triphosphate trisodium salt hydrate
CAS:5'-GTP trisodium salt hydrate activates G proteins and is a precursor for DNA/RNA synthesis.Fórmula:C10H18N5NaO15P3Pureza:98%Forma y color:SolidPeso molecular:564.185Ascochlorin A
CAS:Ascochlorin A, a compound with a dissociation constant (K D) of 3.29 μM, serves as a novel and potent human dihydroorotate dehydrogenase (hDHODH) inhibitorFórmula:C23H31ClO4Forma y color:SolidPeso molecular:406.95BSJ-03-204
CAS:BSJ-03-204 is a selective Cdk4/6 degrader.Fórmula:C43H48N10O8Forma y color:SolidPeso molecular:832.9AAK1-IN-7
AAK1-IN-7 (Compound 16) is a dual inhibitor of AAK1 and GAK with EC50 values of 40 nM and 80 nM, respectively. This compound inhibits the phosphorylation of the AP2-µ2 subunit at the T156 position. However, it demonstrates only weak antiviral activity against RNA viruses.Forma y color:Odour SolidEMD527040 hydrochloride
EMD527040 (hydrochloride) is a potent and selective αvβ6 antagonist with antifibrotic properties. It is applicable in research related to liver cancer and hepatic fibrosis.Forma y color:Odour SolidXanthosine-5'-Triphosphate
CAS:Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes.Fórmula:C10H15N4O15P3Forma y color:SolidPeso molecular:524.1645-Methylcytidine 5′-triphosphate
CAS:5-Methylcytidine 5′-triphosphate (5-Methyl-CTP), a modified nucleoside triphosphate, enhances translational properties and stability while reducing innateFórmula:C10H18N3O14P3Forma y color:SolidPeso molecular:497.18LY2812223
CAS:LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).Fórmula:C10H12N4O4SPureza:98%Forma y color:SolidPeso molecular:284.294,6-Dichloroguaiacol
CAS:4,6-Dichloroguaiacol elicits biochemical and morphological alterations in human peripheral blood lymphocytes in vitro.Fórmula:C7H6Cl2O2Forma y color:SolidPeso molecular:193.02CDK12-IN-2
CAS:CDK12-IN-2 selectively inhibits CDK12 (IC50: 52 nM) with minimal effect on CDK2, CDK7, and CDK9, useful for CDK12 research.
Fórmula:C32H32N6O2Pureza:99.31%Forma y color:SolidPeso molecular:532.64
