Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(114 productos)
- CDK(544 productos)
- Detención del ciclo celular(5 productos)
- Chk(47 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(226 productos)
- HSP(179 productos)
- Integrin(230 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(272 productos)
- PKC(120 productos)
- PLK(25 productos)
- ROCK(63 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
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Se han encontrado 3835 productos de "Ciclo celular / Checkpoint"
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NSC23005 Sodium
CAS:NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.Fórmula:C13H16NNaO4SPureza:99.64%Forma y color:SolidPeso molecular:305.32BS-181 hydrochloride
CAS:BS-181 hydrochloride (BS-181 HCl) is a highly selective CDK7 inhibitor with IC50 of 21 nM.Fórmula:C22H32N6·HClPureza:99.21%Forma y color:SolidPeso molecular:416.99Ref: TM-T6162
1mg37,00€2mg52,00€5mg79,00€10mg116,00€25mg250,00€50mg416,00€100mg645,00€200mgA consultar1mL*10mM (DMSO)87,00€Triazavirin
CAS:Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.Fórmula:C5H7N6NaO5SPureza:99.55%Forma y color:SolidPeso molecular:286.2NSC 617145
CAS:NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependentFórmula:C13H10Cl4N2O4Pureza:99.78%Forma y color:SolidPeso molecular:400.04Ref: TM-T9168
1mg34,00€2mg49,00€5mg73,00€10mg90,00€25mg164,00€50mg227,00€100mg358,00€500mg842,00€1mL*10mM (DMSO)80,00€Natalizumab
CAS:Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.Pureza:97.15% (SDS-PAGE); 97.2% (SEC-HPLC) - 98.00%Forma y color:LiquidPeso molecular:146.19 kDaJNJ-7706621
CAS:JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.Fórmula:C15H12F2N6O3SPureza:99.1% - 99.85%Forma y color:SolidPeso molecular:394.36Ref: TM-T6126
1mg48,00€5mg100,00€10mg155,00€25mg268,00€50mg432,00€100mg595,00€200mg833,00€1mL*10mM (DMSO)94,00€6-Bromo-2-hydroxy-3-methoxybenzaldehyde
CAS:6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC-95682) is an inhibitor of IRE-1α (IC50 : 0.08 μM).Fórmula:C8H7BrO3Pureza:99.82%Forma y color:SolidPeso molecular:231.04Empesertib
CAS:Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.Fórmula:C29H26FN5O4SPureza:97.45% - 99.4%Forma y color:SolidPeso molecular:559.61Ref: TM-T8487
1mg86,00€5mg173,00€10mg261,00€25mg425,00€50mg583,00€100mg803,00€200mg1.063,00€1mL*10mM (DMSO)231,00€4μ8C
CAS:4μ8C (IRE1 Inhibitor III)(IC50=76 nM) is an effective and specific IRE1 Rnase inhibitor.Fórmula:C11H8O4Pureza:97.48% - 98.45%Forma y color:SolidPeso molecular:204.18Isoindigotin
CAS:Isoindigotin is used in the therapy of Y.
Fórmula:C16H10N2O2Pureza:98.14% - ≥95%Forma y color:SolidPeso molecular:262.26Pyridostatin Trihydrochloride
CAS:Pyridostatin Trihydrochloride (RR-82 Trihydrochloride) is a G-quadruplexe stabilizer, with a Kd of 490 nM.Fórmula:C31H35Cl3N8O5Pureza:99.69%Forma y color:SolidPeso molecular:706.026-Thioinosine
CAS:6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent.Fórmula:C10H12N4O4SPureza:97.74%Forma y color:SolidPeso molecular:284.29CCG-203971
CAS:CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM.Fórmula:C23H21ClN2O3Pureza:98.82% - 99.50%Forma y color:SolidPeso molecular:408.88RI-1
CAS:RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).Fórmula:C14H11Cl3N2O3Pureza:99.3% - 99.62%Forma y color:SolidPeso molecular:361.61TMPyP4 tosylate
CAS:TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.Fórmula:C72H66N8O12S4Pureza:98.61% - 99.85%Forma y color:SolidPeso molecular:1363.6Pyridostatin
CAS:Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome orFórmula:C31H32N8O5Pureza:98%Forma y color:SolidPeso molecular:596.64Adavosertib
CAS:Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.Fórmula:C27H32N8O2Pureza:98.65% - 99.86%Forma y color:SolidPeso molecular:500.6Ref: TM-T2077
5mg46,00€10mg66,00€25mg81,00€50mg96,00€100mg110,00€200mg161,00€500mg260,00€1mL*10mM (DMSO)49,00€CK7
CAS:CK7, a Cdk2/9 inhibitor, is instrumental in the synthesis of Nek1 inhibitors BSc5231 and BSc5367.Fórmula:C14H12N6O2SPureza:99.54%Forma y color:SolidPeso molecular:328.35Ref: TM-T9615
1mg52,00€5mg120,00€10mg187,00€25mg376,00€50mg588,00€100mg905,00€200mg1.216,00€1mL*10mM (DMSO)133,00€Indisulam
CAS:Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.Fórmula:C14H12ClN3O4S2Pureza:98.68% - 99.77%Forma y color:SolidPeso molecular:385.85Ref: TM-T4321
1mg34,00€2mg43,00€5mg63,00€10mg88,00€25mg130,00€50mg198,00€100mg298,00€1mL*10mM (DMSO)69,00€Risdiplam
CAS:Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.Fórmula:C22H23N7OPureza:98.68% - 99.64%Forma y color:SolidPeso molecular:401.46
