Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(94 productos)
- CDK(500 productos)
- Detención del ciclo celular(4 productos)
- Chk(42 productos)
- DYRK(48 productos)
- Dynamin(23 productos)
- Ferroptosis(215 productos)
- HSP(169 productos)
- Integrin(224 productos)
- Kinesina(66 productos)
- LIM quinasa(19 productos)
- Asociado a microtúbulos(261 productos)
- PKC(102 productos)
- PLK(28 productos)
- ROCK(70 productos)
- Rho(2 productos)
- Wee1(15 productos)
- c-Myc(69 productos)
Mostrar 10 subcategorías más
Se han encontrado 3477 productos de "Ciclo celular / Checkpoint"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
PD 407824
CAS:<p>PD 407824 is a chemical BMP sensitiser that promotes increased cellular sensitivity to subthreshold amounts of BMP4.PD 407824 is a potent inhibitor of the checkpoint kinases Chk1 and WEE1 (IC50s: 47 and 97 nM, respectively).</p>Fórmula:C20H12N2O3Pureza:98.02%Forma y color:SolidPeso molecular:328.322'-O-Methyl-5-iodouridine
CAS:<p>2'-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a</p>Fórmula:C10H13IN2O6Pureza:99.89%Forma y color:SolidPeso molecular:384.12TG003
CAS:<p>TG003 is a Clk1/Sty inhibitor that inhibits Clk1 and Clk4, suppresses cancer cell growth, and induces apoptosis.</p>Fórmula:C13H15NO2SPureza:99.46%Forma y color:SolidPeso molecular:249.33Talotrexin
CAS:<p>Talotrexin (PT523), a nonpolyglutamatable antifolate analog of Aminopterin, inhibits DHFR and RFC, targeting tumor growth.</p>Fórmula:C27H27N9O6Forma y color:SolidPeso molecular:573.56kb-NB77-78
CAS:<p>kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).</p>Fórmula:C18H25NO3SiPureza:99.54%Forma y color:SolidPeso molecular:331.48Rabusertib
CAS:<p>Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small cell lung cancer.</p>Fórmula:C18H22BrN5O3Pureza:98.86% - 99.87%Forma y color:SolidPeso molecular:436.3Trilaciclib
CAS:<p>Trilaciclib is a short-acting, orally effective CDK4/6 inhibitor with IC₅₀ values of 1 nM and 4 nM respectively. enhances antitumour immunity.</p>Fórmula:C24H30N8OPureza:99.624%Forma y color:SolidPeso molecular:446.55Hesperadin
CAS:<p>Hesperadin(IC50=250 nM) effectively inhibits Aurora B.</p>Fórmula:C29H32N4O3SPureza:98.04% - 99.44%Forma y color:SolidPeso molecular:516.65Mps1-IN-3 hydrochloride
<p>Mps1-IN-3 HCl: potent Mps1 inhibitor (IC50: 50 nM), hampers glioblastoma growth, enhances vincristine efficacy in vivo.</p>Fórmula:C26H32ClN7O4SForma y color:SolidPeso molecular:574.09NSC 617145
CAS:<p>NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent</p>Fórmula:C13H10Cl4N2O4Pureza:99.72%Forma y color:SolidPeso molecular:400.04GDC0575 monohydrochloride
CAS:<p>GDC0575 (ARRY575), a potent Chk1 inhibitor, IC50 1.2nM, disrupts cell cycle arrest, allowing DNA repair before mitosis.</p>Fórmula:C16H21BrClN5OPureza:97.85%Forma y color:SolidPeso molecular:414.73AT-9283 HCl
CAS:<p>AT-9283, a multi-targeted kinase inhibitor, is used potentially for the treatment of multiple myeloma.</p>Fórmula:C19H24ClN7O2Forma y color:SolidPeso molecular:417.89Dasabuvir sodium
CAS:<p>Dasabuvir sodium (ABT-333) inhibits HCV NS5B polymerase, targeting genotypes 1a (EC50: 7.7 nM) and 1b (EC50: 1.8 nM).</p>Fórmula:C26H26N3NaO5SForma y color:SolidPeso molecular:515.56Phosphonoformic acid trisodium salt hexa
CAS:<p>Phosphonoformic acid trisodium salt hexa (Sodium phosphonatoformate hexahydrate) is an antiviral drug for the treatment of CMV retinitis.</p>Fórmula:CH12Na3O11PPureza:98%Forma y color:SolidPeso molecular:300.03E7820
CAS:<p>E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).</p>Fórmula:C17H12N4O2SPureza:98.31% - 99.11%Forma y color:SolidPeso molecular:336.37EN4
CAS:<p>EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC.</p>Fórmula:C25H24N2O4Pureza:98.51%Forma y color:SolidPeso molecular:416.47CKI-7 free base
CAS:<p>CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.</p>Fórmula:C11H12ClN3O2SForma y color:SolidPeso molecular:285.75MLS000532223
CAS:<p>MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).</p>Fórmula:C15H9NO3Pureza:98.6%Forma y color:SolidPeso molecular:251.24TH-263
CAS:<p>TH-263 is inactive toward both LIMK1 and LIMK2 and thus can be used as negative control for TH-257, and is a diaryl sulfonamide derivative.</p>Fórmula:C21H20N2O3SPureza:99.54%Forma y color:SolidPeso molecular:380.46iRGD peptide
CAS:<p>iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.</p>Fórmula:C35H57N13O14S2Pureza:98.77%Forma y color:SolidPeso molecular:948.04Orbofiban
CAS:<p>Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation.</p>Fórmula:C17H23N5O4Forma y color:SolidPeso molecular:361.4APTO-253 HCl
CAS:<p>APTO-253 (LOR-253/LT-253) is a small-molecule MTF-1 inhibitor with antitumor properties, reducing cyclin D1, hypoxia, and angiogenesis gene expression.</p>Fórmula:C22H15ClFN5Forma y color:SolidPeso molecular:403.84HA-100 hydrochloride
CAS:<p>HA-100 hydrochloride inhibits protein kinases PKG, PKA, PKC, MLC-kinase (IC50: 4-240 μM) and ROCK.</p>Fórmula:C13H16ClN3O2SForma y color:SolidPeso molecular:313.8BMH-21
CAS:<p>BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.</p>Fórmula:C21H20N4O2Pureza:99.47% - 99.84%Forma y color:SolidPeso molecular:360.41S-trityl-L-Cysteine
CAS:<p>S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5</p>Fórmula:C22H21NO2SPureza:97.02%Forma y color:Almost White To Light Yellow Granular PowderPeso molecular:363.47Apcin
CAS:<p>Apcin: potent APC/C(Cdc20) E3 ligase inhibitor, blocks substrate recognition & mitosis, synergizes with Ts-Arg-OMe.</p>Fórmula:C13H14Cl3N7O4Pureza:96.74%Forma y color:SolidPeso molecular:438.65CHR-6494
CAS:<p>CHR-6494 is a haspin inhibitor that inhibits histone H3T3 phosphorylation (IC50: 2 nM).</p>Fórmula:C16H16N6Pureza:98.78%Forma y color:SolidPeso molecular:292.34Palmatine chloride
CAS:<p>Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.</p>Fórmula:C21H22ClNO4Pureza:97.9% - 99.47%Forma y color:SolidPeso molecular:387.857Datelliptium chloride hydrochloride
CAS:<p>Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.</p>Fórmula:C23H29Cl2N3OPureza:99.46%Forma y color:SolidPeso molecular:434.4CCT 137690
CAS:<p>CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).</p>Fórmula:C26H31BrN8OPureza:98.51% - 99.89%Forma y color:SolidPeso molecular:551.48AZD-7762
CAS:<p>AZD-7762, an effective and specific inhibitor of Chk1（IC50=5 nM）, is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.</p>Fórmula:C17H19FN4O2SPureza:98.96% - 99.19%Forma y color:SolidPeso molecular:362.42Netarsudil free base
CAS:<p>Netarsudil (AR-11324), a ROCK inhibitor, treats glaucoma by increasing eye outflow and lowering IOP, with mild hyperemia as a side effect.</p>Fórmula:C28H27N3O3Forma y color:SolidPeso molecular:453.53NG 52
CAS:<p>NG 52 (NG-52) is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p and the related Pho85p kinase.</p>Fórmula:C16H19ClN6OPureza:98% - 99.34%Forma y color:SolidPeso molecular:346.81LY3143921
CAS:<p>LY3143921 ((S)-Example 2) is an orally active inhibitor of CDC7 kinase with broad in vitro anticancer activity [1].</p>Fórmula:C16H12FN5OForma y color:SolidPeso molecular:309.3RCM-1
CAS:<p>RCM-1 is an inhibitor of FOXM1.</p>Fórmula:C20H12N2OS4Pureza:98.08%Forma y color:SolidPeso molecular:424.58IRE1α kinase-IN-1
CAS:<p>IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM.</p>Fórmula:C26H26ClFN8Pureza:99.18%Forma y color:SolidPeso molecular:504.99Levomefolate calcium
CAS:<p>Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.</p>Fórmula:C20H23CaN7O6Pureza:97.35%Forma y color:Off-White To Pale Yellow SolidPeso molecular:497.52Carotegrast methyl
CAS:<p>Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.</p>Fórmula:C28H26Cl2N4O5Pureza:99.26% - 99.72%Forma y color:SolidPeso molecular:569.44Brr2-IN-3
CAS:<p>Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa.</p>Fórmula:C24H20N4O3SPureza:99.26%Forma y color:SolidPeso molecular:444.51Avotaciclib trihydrochloride
CAS:<p>Avotaciclib trihydrochloride (BEY1107) is an oral CDK1 inhibitor targeting advanced pancreatic cancer.</p>Fórmula:C13H14Cl3N7OPureza:99%Forma y color:SolidPeso molecular:390.653'-Deoxyguanosine
CAS:<p>3'-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors.</p>Fórmula:C10H13N5O4Pureza:98.85% - 98.96%Forma y color:SolidPeso molecular:267.24Tempo
CAS:<p>Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a</p>Fórmula:C9H18NOPureza:98.35%Forma y color:Orange Crystals Or PowderPeso molecular:156.25AI-10-49
CAS:<p>AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.</p>Fórmula:C30H22F6N6O5Pureza:97.14%Forma y color:SolidPeso molecular:660.526-Thioinosine
CAS:<p>6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent.</p>Fórmula:C10H12N4O4SPureza:97.74%Forma y color:SolidPeso molecular:284.29Deoxythymidine triphosphate
CAS:<p>Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.</p>Fórmula:C10H14N2Na3O14P3Pureza:99.78%Forma y color:White Amorphous PowderPeso molecular:548.11PKD-IN-1 dihydrochloride (956121-30-5 free base)
CAS:<p>CRT0066101 dihydrochloride is an inhibitor of PKD.</p>Fórmula:C18H21Cl3N4OPureza:99.5%Forma y color:SolidPeso molecular:415.75Brequinar
CAS:<p>Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.</p>Fórmula:C23H15F2NO2Pureza:99.1% - 99.57%Forma y color:SolidPeso molecular:375.37Pyridostatin hydrochloride
CAS:<p>Pyridostatin hydrochloride stabilizes G-quadruplex DNA (Kd=490nM), inhibits cancer cell growth, and reduces SRC in breast cancer.</p>Fórmula:C31H37Cl5N8O5Forma y color:SolidPeso molecular:778.94BMS-8
CAS:<p>BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.</p>Fórmula:C27H28BrNO3Pureza:98.88%Forma y color:SolidPeso molecular:494.42Mps1-IN-1 dihydrochloride
CAS:<p>Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM.</p>Fórmula:C28H35Cl2N5O4SForma y color:SolidPeso molecular:608.58UNC10217938A
CAS:<p>UNC10217938A is a 3-deazapteridine analog, has strong oligonucleotide enhancing effects.</p>Fórmula:C26H28N6O2Pureza:98%Forma y color:SolidPeso molecular:456.54LY3405105
CAS:<p>LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-</p>Fórmula:C26H39N7O3Pureza:99.66%Forma y color:SolidPeso molecular:497.63Barasertib-HQPA
CAS:<p>Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.</p>Fórmula:C26H30FN7O3Pureza:98.43% - 99.29%Forma y color:SolidPeso molecular:507.56N6,N6-Dimethyladenosine
CAS:<p>N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.</p>Fórmula:C12H17N5O4Pureza:98.79%Forma y color:White PowderPeso molecular:295.29Proguanil
CAS:<p>Proguanil (Chloroguanide) is a prophylactic antimalarial drug that acts primarily through its active metabolite, Cycloguanil, which inhibits the DHFR enzyme .</p>Fórmula:C11H16ClN5Pureza:99.6%Forma y color:SolidPeso molecular:253.73FIT-039
CAS:<p>FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).</p>Fórmula:C17H18FN3SPureza:98.61%Forma y color:SolidPeso molecular:315.41NVP-LCQ195
CAS:<p>NVP-LCQ195 (LCQ-195) (AT9311) is a potent inhibitor of CDK1, CDK2, CDK3 and CDK5 (IC50: 1-42 nM).</p>Fórmula:C17H19Cl2N5O4SPureza:99.56% - 99.85%Forma y color:SolidPeso molecular:460.33JSH-150
CAS:<p>JSH-150 is a highly selective CDK9 inhibitor(IC50 : 1 nM).</p>Fórmula:C24H33ClN6O2SPureza:99.96% - 99.96%Forma y color:SolidPeso molecular:505.08Cilengitide
CAS:<p>Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.</p>Fórmula:C27H40N8O7Pureza:98% - 99.8%Forma y color:SolidPeso molecular:588.66Atuveciclib
CAS:<p>Atuveciclib Racemate is an oral CDK9 inhibitor with a 13 nM IC50, targeting P-TEFb/CDK9 selectively.</p>Fórmula:C18H18FN5O2SPureza:98.8%Forma y color:SolidPeso molecular:387.432-Chloroadenosine
CAS:<p>2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectively</p>Fórmula:C10H12ClN5O4Pureza:99.23%Forma y color:White PowderPeso molecular:301.69Fosifloxuridine nafalbenamide
CAS:<p>Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.</p>Fórmula:C29H29FN3O9PPureza:95.87%Forma y color:SolidPeso molecular:613.53GSK461364
CAS:<p>GSK461364 (GSK461364A)(Ki=2.2 nM) inhibits purified Plk1 .The specificity of GSK461364 for Plk1 is more than 1000-fold over Plk2/3.</p>Fórmula:C27H28F3N5O2SPureza:99% - 99.73%Forma y color:SolidPeso molecular:543.6ILK-IN-2
CAS:<p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>Fórmula:C30H30F3N5OPureza:99.30%Forma y color:SolidPeso molecular:533.593-AP
CAS:<p>3-AP (Triapine) is a novel inhibitor of the M2 subunit of ribonucleotide reductase (RR).</p>Fórmula:C7H9N5SPureza:97.33% - 99.87%Forma y color:SolidPeso molecular:195.24CW-069
CAS:<p>CW-069 (IC50=75 μM）, an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.</p>Fórmula:C23H21IN2O3Pureza:97.52% - 99.52%Forma y color:SolidPeso molecular:500.33CCG-203971
CAS:<p>CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM.</p>Fórmula:C23H21ClN2O3Pureza:98.82% - 99.50%Forma y color:SolidPeso molecular:408.88SP-146
<p>SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).</p>Fórmula:C25H20FN7OPureza:97.82%Forma y color:SolidPeso molecular:453.47LY2880070
CAS:<p>LY2880070 is a new checkpoint kinase 1 (CHK1) inhibitor for cancer therapy.</p>Fórmula:C19H23N7O2Pureza:99.77%Forma y color:SolidPeso molecular:381.43BMS-1001
CAS:<p>BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).</p>Fórmula:C35H34N2O7Pureza:98.43%Forma y color:SolidPeso molecular:594.7WNK-IN-11
CAS:<p>WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)</p>Fórmula:C21H21Cl2N5OSPureza:98.32%Forma y color:SolidPeso molecular:462.4Bractoppin
CAS:<p>Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits</p>Fórmula:C25H23FN4OPureza:98.38%Forma y color:SolidPeso molecular:414.47DMT-2′Fluoro-dU Phosphoramidite
CAS:<p>DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.</p>Fórmula:C39H46FN4O8PPureza:99.5%Forma y color:SolidPeso molecular:748.78BMS-5
CAS:<p>BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively.</p>Fórmula:C17H14Cl2F2N4OSPureza:98.01% - 99.88%Forma y color:SolidPeso molecular:431.292′-Deoxy-2′-fluoroguanosine
CAS:<p>2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM).</p>Fórmula:C10H12FN5O4Pureza:99.89%Forma y color:SolidPeso molecular:285.23AZD-5597
CAS:<p>AZD-5597 ((S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methylamino)pyrrolidin-1-yl)methanone) is a potent</p>Fórmula:C23H28FN7OPureza:98.01%Forma y color:SolidPeso molecular:437.51WR99210 hydrochloride(47326-86-3 free base)
CAS:<p>WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target.</p>Fórmula:C14H19Cl4N5O2Pureza:97.77% - 99.8%Forma y color:SolidPeso molecular:431.14Saccharin 1-methylimidazole
CAS:<p>Saccharin 1-methylimidazole (SMI) is a general-purpose activator used for DNA and RNA synthesis.</p>Fórmula:C7H5NO3S·C4H6N2Pureza:98.21%Forma y color:SolidPeso molecular:265.29LDC-4297 HCl (1453834-21-3(free base))
<p>LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.</p>Fórmula:C23H29ClN8OPureza:100%Forma y color:SolidPeso molecular:469.02Ispinesib
CAS:<p>Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic</p>Fórmula:C30H33ClN4O2Pureza:98% - 99.09%Forma y color:SolidPeso molecular:517.06Bonafton
CAS:<p>Bonafton (Bonaphthone) is an antiviral agent.</p>Fórmula:C10H5BrO2Pureza:97.16%Forma y color:SolidPeso molecular:237.053-Deazauridine
CAS:<p>3-Deazauridine (NSC-126849), a uridine analog, blocks CTP synthesis by competing with CTP synthetase.</p>Fórmula:C10H13NO6Pureza:99.86%Forma y color:SolidPeso molecular:243.21Calcium N5-methyltetrahydrofolate
CAS:<p>Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and</p>Fórmula:C20H23CaN7O6Pureza:99.41%Forma y color:SolidPeso molecular:497.51CC-671
CAS:<p>CC-671 is a dual TTK protein kinase (IC50: 0.005 μM) /CLK2 (IC50: 0.006 μM) inhibitor.</p>Fórmula:C28H28N6O4Pureza:98.66% - 98.8%Forma y color:SolidPeso molecular:512.56Arg-Gly-Asp TFA (99896-85-2(free base))
<p>Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.</p>Fórmula:C14H23F3N6O8Pureza:99.2% - ≥98%Forma y color:SolidPeso molecular:460.36Trifluridine/tipiracil hydrochloride mixture
CAS:<p>Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a</p>Fórmula:C29H34Cl2F6N8O12Pureza:98% - 99.79%Forma y color:SolidPeso molecular:871.53Vidofludimus
CAS:<p>Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).</p>Fórmula:C20H18FNO4Pureza:98.33% - 99.58%Forma y color:SolidPeso molecular:355.36EHT 1864 2HCl
CAS:<p>EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.</p>Fórmula:C25H29Cl2F3N2O4SPureza:98.39% - 99.42%Forma y color:SolidPeso molecular:581.47Danofloxacin
CAS:<p>Danofloxacin (Danofloxacin free base) is a fluoroquinolone antibiotic used in veterinary medicine.</p>Fórmula:C19H20FN3O3Pureza:99.77% - 99.8%Forma y color:SolidPeso molecular:357.38GPRP acetate (67869-62-9 free base)
CAS:<p>GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex.</p>Fórmula:C20H35N7O7Pureza:>99.99%Forma y color:SolidPeso molecular:485.536-O-Methyl Guanosine
CAS:<p>6-O-Methyl Guanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line.</p>Fórmula:C11H15N5O5Pureza:97.5%Forma y color:SolidPeso molecular:297.27MLN0905
CAS:<p>MLN0905 (PLK1 Inhibitor) is an effective PLK1 inhibitor(IC50=2 nM).</p>Fórmula:C24H25F3N6SPureza:97.17% - 98%Forma y color:SolidPeso molecular:486.56Levoleucovorin Calcium
CAS:<p>Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.</p>Fórmula:C20H21N7O7·CaPureza:99.07% - ≥98%Forma y color:White Crystalline PowderPeso molecular:511.5BMS-3
CAS:<p>BMS-3 is a potent LIMK inhibitor with IC50s of 5 nM and 6 nM for LIMK1 and LIMK2, respectively.</p>Fórmula:C17H12Cl2F2N4OSPureza:99.31% - 99.81%Forma y color:SolidPeso molecular:429.27Fanotaprim
CAS:<p>Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor.</p>Fórmula:C19H22N8OPureza:98.1%Forma y color:SolidPeso molecular:378.43TR-14035
CAS:<p>TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).</p>Fórmula:C24H21Cl2NO5Pureza:98.98%Forma y color:SolidPeso molecular:474.33EOAI3402143
CAS:<p>EOAI3402143 inhibits Usp9x and Usp24 activity, increases tumor cell apoptosis.</p>Fórmula:C25H28Cl2N4O3Pureza:99.6%Forma y color:SolidPeso molecular:503.42LY3177833
CAS:<p>LY3177833 is an Cdc7 kinase inhibitor (IC50 : 3.3 nM)</p>Fórmula:C16H12FN5OPureza:99.87%Forma y color:SolidPeso molecular:309.3LXW7
CAS:<p>LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (</p>Fórmula:C29H48N12O12S2Pureza:>99.99%Forma y color:SolidPeso molecular:820.89AT9283
CAS:<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Fórmula:C19H23N7O2Pureza:99.83% - 99.98%Forma y color:SolidPeso molecular:381.43MSC2530818
CAS:<p>MSC2530818 is an effective, selective and orally available CDK8 inhibitor (IC50: 2.6 nM).</p>Fórmula:C18H17ClN4OPureza:98.93%Forma y color:SolidPeso molecular:340.81GDC-0575
CAS:<p>GDC-0575 (ARRY-575) is a highly-selective oral small-molecule Chk1 inhibitor(IC50 of 1.2 nM).</p>Fórmula:C16H20BrN5OPureza:≥95%Forma y color:SolidPeso molecular:378.27TCS7010
CAS:<p>TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.</p>Fórmula:C31H31ClFN7O2Pureza:98.49% - 99.62%Forma y color:SolidPeso molecular:588.07HA-100
CAS:<p>HA-100 is an inhibitor of protein kinase</p>Fórmula:C13H15N3O2SPureza:99.44%Forma y color:Pale Yellow Crystalline SolidPeso molecular:277.34Zoliflodacin
CAS:<p>Zoliflodacin (ETX0914) (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor.</p>Fórmula:C22H22FN5O7Pureza:99.82% - 99.93%Forma y color:SolidPeso molecular:487.44BS-181 dihydrochloride
CAS:<p>BS-181 dihydrochloride: Potent CDK7 inhibitor (IC50: 21 nM), less effective on CDK2/5/9, no impact on CDK1/4/6, halts cancer cell growth, triggers apoptosis.</p>Fórmula:C22H34Cl2N6Forma y color:SolidPeso molecular:453.46GNF2133 hydrochloride
CAS:<p>GNF2133 hydrochloride: selective oral DYRK1A inhibitor (IC50: 0.0062 μM), boosts β-cell growth and insulin, potential for type 1 diabetes research.</p>Fórmula:C24H31ClN6O2Forma y color:SolidPeso molecular:471.06-Thio-2'-Deoxyguanosine
CAS:<p>6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.</p>Fórmula:C10H13N5O3SPureza:97.52%Forma y color:SolidPeso molecular:283.31POL1-IN-1
CAS:<p>POL1-IN-1 (Compound 3A) 是一种RNA 聚合酶 1 POL1抑制剂，IC50值低于 0.5 uM。 它能有效抑制A375恶性黑色素瘤细胞系中RNA 聚合酶I 的转录。</p>Fórmula:C21H20N6Pureza:98% - 98.01%Forma y color:SolidPeso molecular:356.42Ocifisertib(CFI-400945 free base)
CAS:<p>Ocifisertib (CFI-400945 free base) is a potent, selective and orally active inhibitor of polo-like kinase 4.Cost-effective and quality-assured.</p>Fórmula:C33H34N4O3Pureza:98.53% - 99.04%Forma y color:SolidPeso molecular:534.65N1-Methylpseudouridine
CAS:<p>N1-Methylpseudouridine (1-Methylpseudouridine) is a methylpseudouridine and enhances translation through eIF2α-dependent and independent mechanisms by</p>Fórmula:C10H14N2O6Pureza:98.95% - 99.88%Forma y color:SolidPeso molecular:258.23LJI308
CAS:<p>LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.</p>Fórmula:C21H18F2N2O2Pureza:99.73% - 99.87%Forma y color:SolidPeso molecular:368.38Acelarin
CAS:<p>Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.</p>Fórmula:C25H27F2N4O8PPureza:99.26%Forma y color:SolidPeso molecular:580.47CYC-116
CAS:<p>CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active</p>Fórmula:C18H20N6OSPureza:97.36% - 97.59%Forma y color:SolidPeso molecular:368.46THZ1
CAS:<p>THZ1 (CDK7 inhibitor) is a selective inhibitor of CDK7, binding to the Cys residue located at the outer end of the classical kinase domain. Cost-effective and quality-assured.</p>Fórmula:C31H28ClN7O2Pureza:95.09% - 99.27%Forma y color:SolidPeso molecular:566.05PFM01
CAS:<p>PFM01 inhibits MRE11 enzyme, steering DSBR towards NHEJ over HR.</p>Fórmula:C14H15NO2S2Pureza:98.68%Forma y color:SolidPeso molecular:293.4Simeprevir
CAS:<p>Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.</p>Fórmula:C38H47N5O7S2Pureza:99.45% - 99.92%Forma y color:SolidPeso molecular:749.94Aurora kinase inhibitor-3
CAS:<p>Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,</p>Fórmula:C21H18F3N5OPureza:98.91%Forma y color:SolidPeso molecular:413.4GW406108X(Z/E)
CAS:<p>GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .</p>Fórmula:C20H11Cl2NO4Pureza:98.23%Forma y color:SolidPeso molecular:400.21Dalpiciclib
CAS:<p>Dalpiciclib (SHR-6390) selectively inhibits CDK4/6 (IC50: 12.4/9.9 nM), is orally available, and impedes esophageal cancer growth.</p>Fórmula:C25H30N6O2Pureza:99.69%Forma y color:SolidPeso molecular:446.54MLN8054
CAS:<p>MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.</p>Fórmula:C25H15ClF2N4O2Pureza:98.07% - 98.26%Forma y color:SolidPeso molecular:476.86A-205804
CAS:<p>A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.</p>Fórmula:C15H12N2OS2Pureza:98.07% - 98.52%Forma y color:SolidPeso molecular:300.4TH588 hydrochloride
CAS:<p>TH588 hydrochloride is first-in-class inhibitor of nudix hydrolase family that selectively and effectively bind and inhibit the MTH1 with IC50 value of 5 nM.</p>Fórmula:C13H13Cl3N4Forma y color:SolidPeso molecular:331.63Methotrexate metabolite
CAS:<p>DAMPA, active metabolite of Methotrexate, is a chemotherapeutic and immunosuppressive folic acid antagonist.</p>Fórmula:C15H15N7O2Pureza:95.60% - 97.59%Forma y color:SolidPeso molecular:325.33SBC-115337
CAS:<p>SBC-115337 is a PCSK9 inhibitor.</p>Fórmula:C29H19N3O4Pureza:99.41%Forma y color:SolidPeso molecular:473.48BTYNB
CAS:<p>BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1. MDK6620 downregulates β-TrCP1 mRNA and reduces activation of NF-κB.</p>Fórmula:C12H9BrN2OSPureza:≥95%Forma y color:SolidPeso molecular:309.18Y16 acetate(429653-73-6 free base)
<p>Y16 acetate(429653-73-6 free base) is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA</p>Fórmula:C51H74N14O13Pureza:98%Forma y color:SolidPeso molecular:1091.24Briciclib
CAS:<p>Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.</p>Fórmula:C19H23O10PSPureza:98% - 99.84%Forma y color:SolidPeso molecular:474.42Nemorubicin
CAS:<p>Nemorubicin (PNU 152243) is a unique doxorubicin variant with varied antitumor action, metabolism, and toxicity, effective against resistant tumors.</p>Fórmula:C32H37NO13Pureza:97.4%Forma y color:SolidPeso molecular:643.64Amenamevir
CAS:<p>Amenamevir (ASP2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mL</p>Fórmula:C24H26N4O5SPureza:99.00% - 99.86%Forma y color:SolidPeso molecular:482.55Garenoxacin mesylate hydrate
CAS:<p>Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strains</p>Fórmula:C23H20F2N2O4·CH4O3S·H2OPureza:99.56%Forma y color:SolidPeso molecular:540.53CCT245737
CAS:<p>CCT245737 is an orally active, selective Chk1 inhibitor, and is >1,000-fold selective over CHK2 and CDK1.Cost-effective and quality-assured.</p>Fórmula:C16H16F3N7OPureza:98.06% - 99.69%Forma y color:SolidPeso molecular:379.34IMP-1088
CAS:<p>IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.</p>Fórmula:C25H29F2N5OPureza:98.48% - 99.52%Forma y color:SolidPeso molecular:453.53TAK-960 monohydrochloride
CAS:<p>TAK-960 monohydrochloride, an oral compound, inhibits PLK1 (IC50=0.8 nM), PLK2, PLK3, stunts cancer cell growth, and is effective in tumor models.</p>Fórmula:C27H35ClF3N7O3Forma y color:SolidPeso molecular:598.07Pritelivir
CAS:<p>Pritelivir (BAY 57-1293) (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM).</p>Fórmula:C18H18N4O3S2Pureza:97.96% - 99.42%Forma y color:SolidPeso molecular:402.49Senexin A
CAS:<p>Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd values of 0.83 microns and 0.31 microns, respectively.</p>Fórmula:C17H14N4Pureza:99.74%Forma y color:SolidPeso molecular:274.32SEL120-34A HCl
CAS:<p>SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with IC50s of 4.4 nM and 10.4 nM , respectively</p>Fórmula:C15H19Br2ClN4Pureza:98.13% - 98.47%Forma y color:SolidPeso molecular:450.6FEN1-IN-SC13
CAS:<p>FEN1-IN-SC13 is a potent inhibitor of DNA fragmentation endonuclease 1 (FEN1)</p>Fórmula:C24H23N3O3SPureza:98.02%Forma y color:SolidPeso molecular:433.52Palbociclib
CAS:<p>Palbociclib is an oral CDK4/6 inhibitor, halts Rb phosphorylation, arrests cell cycle, and curbs tumor growth.</p>Fórmula:C24H29N7O2Pureza:98% - 99.9%Forma y color:SolidPeso molecular:447.53LY2334737
CAS:<p>LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.</p>Fórmula:C17H25F2N3O5Pureza:98.82%Forma y color:SolidPeso molecular:389.39MLS-573151
CAS:<p>MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).</p>Fórmula:C21H19N3O2SPureza:98.80%Forma y color:SolidPeso molecular:377.46Dalpiciclib hydrochloride
<p>Dalpiciclib (SHR-6390) HCl is an oral CDK4/6 inhibitor with IC50s of 12.4/9.9 nM, an antitumor for breast and esophageal cancers.</p>Fórmula:C25H31ClN6O2Forma y color:SolidPeso molecular:483.01SBC-110736
CAS:<p>SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor</p>Fórmula:C26H27N3O2Pureza:99.44%Forma y color:SolidPeso molecular:413.51DMTr-LNA-5MeU-3-CED-phosphoramidite
CAS:<p>DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.</p>Fórmula:C41H49N4O9PPureza:98.28%Forma y color:SolidPeso molecular:772.82FOY 251
CAS:<p>FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.</p>Fórmula:C17H19N3O7SPureza:97.11% - 99.33%Forma y color:SolidPeso molecular:409.415-BrdU
CAS:<p>5-BrdU (Broxuridine) is a nucleoside analogue, detect proliferating cells and compete with thymidine for incorporation into DNA. High-Quality, Low-Cost!</p>Fórmula:C9H11BrN2O5Pureza:99.54% - 99.87%Forma y color:Crystals From Absolute Ethanol Physical Description White Crystalline Powder (Ntp 1992)Peso molecular:307.1TAK-960 hydrochloride
CAS:<p>TAK-960 hydrochloride is an oral, potent PLK1 inhibitor with IC50 of 0.8 nM, effective against various tumor cells and xenografts.</p>Fórmula:C27H35ClF3N7O3Forma y color:SolidPeso molecular:598.06BMS-1166
CAS:<p>BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.</p>Fórmula:C36H33ClN2O7Pureza:99.22%Forma y color:SolidPeso molecular:641.11SCH900776
CAS:<p>SCH900776 (MK-8776) is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities.</p>Fórmula:C15H18BrN7Pureza:96.69% - 99.6%Forma y color:SolidPeso molecular:376.25TH5427 hydrochloride
CAS:<p>TH5427 HCl inhibits NUDT5 with 29 nM IC50; 690x more selective over MTH1; blocks ATP in breast cancer cells, hindering growth.</p>Fórmula:C20H21Cl3N8O3Forma y color:SolidPeso molecular:527.79Cucurbitacin B
CAS:<p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>Fórmula:C32H46O8Pureza:97.1% - 99.33%Forma y color:SolidPeso molecular:558.7Ibezapolstat
CAS:<p>Ibezapolstat (ACX-362E) is an antibiotic with antibacterial activity that inhibits Clostridium difficile.</p>Fórmula:C18H20Cl2N6O2Pureza:98% - 99.429%Forma y color:SolidPeso molecular:423.3RI-1
CAS:<p>RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).</p>Fórmula:C14H11Cl3N2O3Pureza:99.3% - 99.62%Forma y color:SolidPeso molecular:361.61Y16
CAS:<p>Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.</p>Fórmula:C24H20N2O3Pureza:98.26% - 99.32%Forma y color:SolidPeso molecular:384.43TMPyP4 tosylate
CAS:<p>TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.</p>Fórmula:C72H66N8O12S4Pureza:98.61% - 99.85%Forma y color:SolidPeso molecular:1363.6RNase L-IN-2
CAS:<p>RNase L-IN-2 activates RNase L at 22 uM, has antiviral effects on various RNA viruses, non-toxic at effective levels.</p>Fórmula:C16H14N2O2SPureza:98.81%Forma y color:SolidPeso molecular:298.365'-Deoxy-5-fluorocytidine
CAS:<p>5'-Deoxy-5-fluorocytidine is an intermediate metabolite of the DNA synthesis inhibitor capecitabine.</p>Fórmula:C9H12FN3O4Pureza:99.67%Forma y color:White SolidPeso molecular:245.21PNU112455A hydrochloride
CAS:<p>PNU112455A hydrochloride is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.</p>Fórmula:C10H12ClN5O2SPureza:98.58% - 99.22%Forma y color:SolidPeso molecular:301.75Tirofiban hydrochloride monohydrate
CAS:<p>Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.</p>Fórmula:C22H39ClN2O6SPureza:98.81% - >99.99%Forma y color:White SolidPeso molecular:495.07STAMBP-IN-1
CAS:<p>STAMBP-IN-1 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release after</p>Fórmula:C27H28N4O4SPureza:99.64%Forma y color:SolidPeso molecular:504.62-Aminofluorene
CAS:<p>2-Aminofluorene (2-Fluorenamine) is a biochemical.</p>Fórmula:C13H11NPureza:99.9%Forma y color:Light Yellow CrystallinePeso molecular:181.23ON-013100
CAS:<p>ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.</p>Fórmula:C19H22O7SPureza:98.27%Forma y color:SolidPeso molecular:394.44Pyridostatin
CAS:<p>Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or</p>Fórmula:C31H32N8O5Pureza:98%Forma y color:SolidPeso molecular:596.64Ribociclib succinate hydrate
CAS:<p>Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively).</p>Fórmula:C27H38N8O6Pureza:98%Forma y color:SolidPeso molecular:570.65110074-G5
CAS:<p>10074-G5 is an inhibitor of c-Myc-Max dimerization.</p>Fórmula:C18H12N4O3Pureza:99.51% - 99.67%Forma y color:SolidPeso molecular:332.31IMM-H007
CAS:<p>IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression</p>Fórmula:C22H23N5O8Pureza:97.73%Forma y color:SolidPeso molecular:485.45Phthalazinone pyrazole
CAS:<p>Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.</p>Fórmula:C18H15N5OPureza:97.03%Forma y color:SolidPeso molecular:317.34A-286982
CAS:<p>A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.</p>Fórmula:C24H27N3O4SPureza:97.81%Forma y color:SolidPeso molecular:453.55Adavosertib
CAS:<p>Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.</p>Fórmula:C27H32N8O2Pureza:98.65% - 99.86%Forma y color:SolidPeso molecular:500.6PF 477736
CAS:<p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>Fórmula:C22H25N7O2Pureza:97.58% - 99.94%Forma y color:SolidPeso molecular:419.48ML216
CAS:<p>ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).</p>Fórmula:C15H9F4N5OSPureza:98.12%Forma y color:SolidPeso molecular:383.32Fadraciclib
CAS:<p>Fadraciclib (CYC065) is an orally available, second-generation ATP-competitive inhibitor of CDK2/CDK9 kinases (IC50s: 5/26 nM).</p>Fórmula:C21H31N7OPureza:99.75%Forma y color:SolidPeso molecular:397.52Mitonafide
CAS:<p>Mitonafide (NSC-300288) suppresses the activity of M. tuberculosis NAD+ dependent DNA ligase A. Mitonafide is a DNA intercalating agent.</p>Fórmula:C16H15N3O4Pureza:99.89%Forma y color:SolidPeso molecular:313.31CHR-6494 TFA
CAS:<p>CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.</p>Fórmula:C18H17F3N6O2Pureza:99.50%Forma y color:SolidPeso molecular:406.36CAN508
CAS:<p>CAN508: potent CDK9/T1 inhibitor; IC50 0.35 μM, Cdk2/E; Ki 13.3 μM, IC50 20 μM; 38x selective; antitumor.</p>Fórmula:C9H10N6OPureza:98.65%Forma y color:SolidPeso molecular:218.22CK7
CAS:<p>CK7, a Cdk2/9 inhibitor, is instrumental in the synthesis of Nek1 inhibitors BSc5231 and BSc5367.</p>Fórmula:C14H12N6O2SPureza:99.54%Forma y color:SolidPeso molecular:328.35HMN-214
CAS:<p>HMN-214 (IVX-214) is a potent PLK1 inhibitor with an average IC50 of 0.12 μM.</p>Fórmula:C22H20N2O5SPureza:98% - >99.99%Forma y color:SolidPeso molecular:424.47TAK-960
CAS:<p>TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.</p>Fórmula:C27H34F3N7O3Pureza:97.06%Forma y color:SolidPeso molecular:561.6Indisulam
CAS:<p>Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.</p>Fórmula:C14H12ClN3O4S2Pureza:98.68% - 99.77%Forma y color:SolidPeso molecular:385.85Cyclo(-RGDfK) TFA
CAS:<p>Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).</p>Fórmula:C29H42F3N9O9Pureza:98.99% - 99.54%Forma y color:SolidPeso molecular:717.69GSK2850163 hydrochloride
CAS:<p>GSK2850163 hydrochloride is a novel IRE1α inhibitor with IC50 of 20 nM for kinase and 200 nM for RNA enzyme.</p>Fórmula:C24H30Cl3N3OForma y color:SolidPeso molecular:482.87TAK-632
CAS:<p>TAK-632 is a potent pan-Raf inhibitor.</p>Fórmula:C27H18F4N4O3SPureza:98% - 99.5%Forma y color:SolidPeso molecular:554.52SBC-115076
CAS:<p>SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.</p>Fórmula:C31H33N3O5Pureza:97.07% - 99.89%Forma y color:SolidPeso molecular:527.617BIO
CAS:<p>7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.</p>Fórmula:C16H10BrN3O2Pureza:99.67%Forma y color:SolidPeso molecular:356.17Apcin-A
CAS:<p>Apcin-A is an anaphase-promoting complex (APC) inhibitor.</p>Fórmula:C10H14Cl3N5O2Forma y color:SolidPeso molecular:342.61Roniciclib
CAS:<p>Roniciclib (BAY 1000394) is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC(50) values in the range between 5 and 25 nmol/L.</p>Fórmula:C18H21F3N4O3SPureza:98% - 98.63%Forma y color:SolidPeso molecular:430.44GLPG0187
CAS:<p>GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).</p>Fórmula:C29H37N7O5SPureza:99.4% - 99.70%Forma y color:SolidPeso molecular:595.71Tiazofurin
CAS:<p>Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.</p>Fórmula:C9H12N2O5SPureza:99.91%Forma y color:SolidPeso molecular:260.272'-Deoxy-2'-fluorocytidine
CAS:<p>2'-Deoxy-2'-fluorocytidine is an nucleoside analog and inhibits of Crimean-Congo hemorrhagic fever virus (CCHFV) replication potently.</p>Fórmula:C9H12FN3O4Pureza:99.90%Forma y color:White Or Almost White Crystalline PowderPeso molecular:245.21Cetraxate hydrochloride
CAS:<p>Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.</p>Fórmula:C17H24ClNO4Pureza:99.75%Forma y color:SolidPeso molecular:341.83PF-06873600
CAS:<p>PF-06873600: oral CDK inhibitor (CDK2/4/6), Ki 0.09-0.16 nM, potential anticancer drug.</p>Fórmula:C20H27F2N5O4SPureza:98.77% - 99.55%Forma y color:SolidPeso molecular:471.52Hu7691
CAS:<p>Hu7691 is an Akt inhibitor that inhibits Akt1, Akt2, and Akt3, suppresses neuroblastoma cell proliferation, and induces differentiation of neuroblastoma cells.</p>Fórmula:C22H22ClF3N4OPureza:99.81%Forma y color:SolidPeso molecular:450.88Risdiplam
CAS:<p>Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.</p>Fórmula:C22H23N7OPureza:98.68% - 99.64%Forma y color:SolidPeso molecular:401.46Palmatine
CAS:<p>Palmatine, also known as Burasaine, inhibits dopamine production and may treat flavivirus, jaundice, dysentery, hypertension, and liver issues.</p>Fórmula:C21H22NO4Pureza:96.28% - 99.49%Forma y color:SolidPeso molecular:352.4AT7519 TFA
CAS:<p>AT7519 inhibits CDK1-6 kinases; IC50 ranges 0.018-0.66 μM.</p>Fórmula:C18H18Cl2F3N5O4Forma y color:SolidPeso molecular:496.27Poloxin
CAS:<p>Poloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).</p>Fórmula:C18H19NO3Pureza:99.19%Forma y color:SolidPeso molecular:297.35Palbociclib dihydrochloride
<p>Palbociclib, oral CDK4/6 inhibitor (IC50: 11/16 nM), targets HR+/HER2- breast cancer and hepatocellular carcinoma.</p>Fórmula:C24H31Cl2N7O2Forma y color:SolidPeso molecular:520.45SPHINX
CAS:<p>SPHINX is a new generation inhibitor of SPRK1</p>Fórmula:C17H17F3N2O3Pureza:99.29%Forma y color:SolidPeso molecular:354.32Cdk5 Substrate acetate
<p>Cdk5, a serine/threonine kinase active in neurons, phosphorylates proteins like histone H1; its synthetic substrate has a Km of 5 µM.</p>Fórmula:C55H103N15O14Pureza:96.21%Forma y color:SolidPeso molecular:1198.5AZD-5438
CAS:<p>AZD-5438 is an effective inhibitor of CDK, for CDK1(IC50=16 nM), CDK2(IC50=6 nM), CDK9(IC50=20 nM).</p>Fórmula:C18H21N5O2SPureza:99.73% - 99.87%Forma y color:SolidPeso molecular:371.46
