Metabolismo
Gli inibitori del metabolismo sono composti che interferiscono con le vie metaboliche, alterando la produzione e l'utilizzo dell'energia all'interno delle cellule. Questi inibitori sono utilizzati per studiare la regolazione del metabolismo, il ruolo delle vie metaboliche in malattie come il cancro e il diabete e per sviluppare nuove strategie terapeutiche. Gli inibitori del metabolismo possono bersagliare vari enzimi e processi coinvolti nella glicolisi, nell'ossidazione degli acidi grassi e in altre funzioni metaboliche. Presso CymitQuimica, offriamo una vasta gamma di inibitori del metabolismo di alta qualità per supportare la tua ricerca in biochimica, disturbi metabolici e sviluppo di farmaci.
Sottocategorie di "Metabolismo"
- AhR(42 prodotti)
- Aminopeptidasi(76 prodotti)
- CETP(20 prodotti)
- Anidrasi carbonica(196 prodotti)
- Caseina chinasi(137 prodotti)
- DHFR(33 prodotti)
- Decarbossilasi(4 prodotti)
- Deidrogenasi(302 prodotti)
- FAAH(66 prodotti)
- FXR(62 prodotti)
- Fattore Xa(87 prodotti)
- Sintasi degli acidi grassi(37 prodotti)
- Ferroptosi(226 prodotti)
- GR(3 prodotti)
- GSNOR(4 prodotti)
- Glucokinasi(57 prodotti)
- Prolil-idrossilasi HIF/HIF(146 prodotti)
- Reduttasi HMG-CoA(34 prodotti)
- Idrossilasi(36 prodotti)
- IDO(84 prodotti)
- LDL(8 prodotti)
- Lipasi(107 prodotti)
- Lipidi(61 prodotti)
- Lipossigenasi(134 prodotti)
- MAO(87 prodotti)
- MPO(2 prodotti)
- NAMPT(40 prodotti)
- P450(6 prodotti)
- PAI-1(26 prodotti)
- PDE(170 prodotti)
- PED(1 prodotti)
- PKM(17 prodotti)
- PPAR(170 prodotti)
- Fosfolipasi(84 prodotti)
- ROR(47 prodotti)
- Recettore dei retinoidi(26 prodotti)
- SGK(10 prodotti)
- Tioredossina(12 prodotti)
- Transferasi(29 prodotti)
- Trasportatore(45 prodotti)
- UGT(4 prodotti)
- Inibitori della xantina ossidasi (XO)(9 prodotti)
Mostrare 34 più sottocategorie
Trovati 9248 prodotti di "Metabolismo"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
3α-Hydroxysteroid dehydrogenase
CAS:3α-Hydroxysteroid dehydrogenase (3α-HSD), encoded by the AKR1C4 gene, is responsible for catalyzing the transformation of 3-ketosteroids into 3α-hydroxyColore e forma:SolidTerpendole C
CAS:Terpendole C, an indole diterpene from A. yamanashiensis, inhibits ACAT with IC50 of 2.1 μM in rats, 0.46 μM in J774 cells, non-toxic.Formula:C32H41NO5Colore e forma:SolidPeso molecolare:519.682Acyl coenzyme A synthetase
CAS:ACS activates fatty acids for lipid metabolism and the TCA cycle.Colore e forma:SolidEstriol 16α-(β-D-glucuronide)
CAS:Estriol 16α-(β-D-glucuronide), an endogenous metabolite found in urine, is utilized in pregnancy research [1] [2].Formula:C24H32O9Colore e forma:SolidPeso molecolare:464.514-Hydroxytryptamine creatinine sulfate
CAS:4-Hydroxytryptamine creatinine sulfate, a derivative of tryptamine, acts as an agonist for neurotransmitters.Formula:C14H21N5O6SColore e forma:SolidPeso molecolare:387.41PEG2000-C-DMG
CAS:PEG2000-C-DMG is a pegylated lipid for Onpattro, reducing transthyretin production via RNAi.Formula:C126H249NO52Colore e forma:SolidPeso molecolare:2000 (Average)Alismanol M
CAS:Alismanol M: FXR agonist, EC50 of 50.25 μM, from Alisma orientale, for cholestasis & NASH research.Formula:C30H48O6Colore e forma:SolidPeso molecolare:504.7ACAT-IN-4
CAS:ACAT-IN-4 inhibits ACAT and NF-κB-mediated transcription.Formula:C32H50N2O5SColore e forma:SolidPeso molecolare:574.827β,25-Dihydroxycholesterol
CAS:7β,25-Dihydroxycholesterol, an endogenous metabolite, functions as chemoattractants for immune cells that express EBI2 [1].Formula:C27H46O3Colore e forma:SolidPeso molecolare:418.65Glutamic acid protease
CAS:Glutamic protease, a proteolytic enzyme characterized by the presence of a glutamic acid residue [1], is exclusive to fungi.Colore e forma:Solid15-LOX-1 inhibitor 1
CAS:9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, & cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.Formula:C22H21ClN2O4Colore e forma:SolidPeso molecolare:412.87Captopril EP Impurity B
CAS:Captopril EP Impurity B, an antihypertensive thiol ACE inhibitor with IC50 of 0.025 μM.Formula:C9H14BrNO3Colore e forma:SolidPeso molecolare:264.12Kallikrein
CAS:Kallikrein is capable of forming the kallikrenase kalinin system (KKS) in plasma and tissues, producing bradykinin and kalin peptides , respectively [1] .Colore e forma:SolidMonaschromone
CAS:Monaschromone, a polyketide, hinders B. cinerea, A. solani, M. oryzae, G. saubinettii growth; MICs 6.25-12.5 μM.Formula:C11H12O4Colore e forma:SolidPeso molecolare:208.21Ftase inhibitor III
CAS:Ftase Inhibitor III, derived from a phenotypic screen, functions as an anion-dependent inhibitor of Farnesyltransferase.Formula:C24H34N6OColore e forma:SolidPeso molecolare:422.577ACAT-IN-3
CAS:ACAT-IN-3, a potent inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT), effectively suppresses NF-κB dependent transcription.Formula:C25H36N2O6SColore e forma:SolidPeso molecolare:492.63Nucleoside hydrolase (IAGNH)
CAS:IAGNH, a glycosidase, breaks N-glycosidic bonds in nucleosides, recycling nucleobases and ribose.Colore e forma:SolidD-Glyceric acid
CAS:D-Glyceric acid, found in urine, aids in Primary hyperoxaluria I & Glutaric Acidemia II research.Formula:C3H6O4Colore e forma:SolidPeso molecolare:106.08Glucose 6-phosphate isomerase
CAS:GPI, also PGI or PHI, is a conserved dimeric glycolytic enzyme, catalyzing glucose-6-phosphate to fructose-6-phosphate isomerization.Colore e forma:Solid(E,Z)-2-propyl-2-Pentenoic Acid
CAS:(E,Z)-2-propyl-2-Pentenoic acid, a valproic acid metabolite, matches its anticonvulsant effects without teratogenicity or hepatotoxicity.Formula:C8H14O2Colore e forma:SolidPeso molecolare:142.2(±)-Hexanoylcarnitine chloride
CAS:(±)-Hexanoylcarnitine chloride is a fatty acid metabolite that breaks down fatty acids into small compounds that can be utilized by the body.Formula:C13H26ClNO4Purezza:99.35%Colore e forma:SolidPeso molecolare:295.8Berninamycin D
CAS:Berninamycin D, a cyclic peptide derived from Streptomyces bernensis through fermentation, is recognized as a fungal metabolite [1].Formula:C45H45N13O13SColore e forma:SolidPeso molecolare:1007.98VDR agonist 3
VDR agonist 3 (Compound E15) is a potent activator of the vitamin D receptor (VDR). It effectively inhibits the activation of hepatic stellate cells (HSC) via VDR. In a model of liver fibrosis induced by CCl4 in mice, VDR agonist 3 significantly alleviates liver fibrosis without causing hypercalcemia.Formula:C24H36O7Colore e forma:SolidPeso molecolare:436.538Phenolic acid
CAS:Phenolic acid is an endogenous metabolite.Formula:C7H8D2O3Purezza:98%Colore e forma:SolidPeso molecolare:144.16LysoFos Glycerol 16
CAS:LysoFos Glycerol 16 is a useful organic compound for research related to life sciences. The catalog number is TF0118 and the CAS number is 326495-22-1.Formula:C22H44NaO9PColore e forma:SolidPeso molecolare:506.549Irsenontrine maleate
CAS:Irsenontrine (E2027) maleate is a selective and orally active inhibitor of phosphodiesterase 9 (PDE9). It can be utilized in the study of neurological diseases.Formula:C26H26N4O7Colore e forma:SolidPeso molecolare:506.515Xanthine oxidase-IN-8
CAS:Xanthine oxidase-IN-8 (Icarisids J) (Compound 7) serves as an inhibitor of xanthine oxidase, exhibiting an inhibitory concentration (IC50) value of 29.71 μM [1Formula:C44H58O23Colore e forma:SolidPeso molecolare:954.923-Hydroxysebacic acid
CAS:3-Hydroxysebacic acid, an endogenous metabolite found in urine, is utilized in the study of Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD) [1] [2].Formula:C10H18O5Colore e forma:SolidPeso molecolare:218.25Febuxostat isopropyl isomer
CAS:Febuxostat isopropyl isomer is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .Formula:C15H14N2O3SColore e forma:SolidPeso molecolare:302.35Glycodeoxycholic acid monohydrate
CAS:Glycodeoxycholic acid monohydrate is a nuclear receptor ligand.Formula:C26H45NO6Colore e forma:SolidPeso molecolare:467.64Ninerafaxstat
CAS:Ninerafaxstat shifts metabolism to glucose, boosts mitochondrial function, and inhibits cancer growth.Formula:C22H29N3O5Purezza:98%Colore e forma:SolidPeso molecolare:415.48(3S,5R)-Fluvastatin D6 sodium
CAS:(3S,5R)-Fluvastatin D6 sodium: deuterium-labeled synthetic HMG-CoA reductase inhibitor with 8 nM IC50.Formula:C24H25FNNaO4Purezza:98%Colore e forma:SolidPeso molecolare:439.49Nampt degrader-2
Nampt degrader-2: a fluorescent PROTAC that degrades NAMPT at IC50 41.9 nM, reducing NAD+ and having anti-tumor effects.Formula:C59H73N9O7SColore e forma:SolidPeso molecolare:1052.33Calcineurin Autoinhibitory Peptide
CAS:Selective inhibitor of Ca2+-calmodulin-dependent protein phosphatase (calcineurin) (IC50 ~ 10 μM). Does not inhibit PP1, PP2A or CaM kinase II (IC50 > 100 mM).Formula:C124H205N39O39S2Purezza:98%Colore e forma:SolidPeso molecolare:2930.34Z-Pro-prolinal
CAS:Z-Pro-prolinal, an orally active PREP inhibitor, IC50: 0.4 nM in porcine.Formula:C18H22N2O4Colore e forma:SolidPeso molecolare:330.387-Hydroxydichloromethotrexate
CAS:7-Hydroxydichloromethotrexate is a methotrexate metabolite.Formula:C20H20Cl2N8O6Colore e forma:SolidPeso molecolare:539.33Tyrosine decarboxylase
CAS:TDC, a PLP-dependent enzyme, removes carboxyl groups from tyrosine, producing tyramine and CO2, found in plants, insects, and microbes.Colore e forma:SolidPhytin
CAS:Phytin has a wide range of applications in life science related research.Formula:C6H6CaMgO24P6Colore e forma:White PowderPeso molecolare:712.32P-orlandin
CAS:P-orlandin, a fungal compound, blocks FREP1, halting P. falciparum's mosquito infection.Formula:C22H18O8Colore e forma:SolidPeso molecolare:410.37Lurasidone metabolite 14326
CAS:Lurasidone metabolite 14326, an active metabolite of the atypical antipsychotic Lurasidone, functions effectively in the body.Formula:C28H36N4O3SPurezza:98%Colore e forma:SolidPeso molecolare:508.68A32390A
CAS:A32390A, an antibiotic inhibitor, shows antimicrobial activity against gram-positive bacteria and fungi.Formula:C18H24N2O8Colore e forma:SolidPeso molecolare:396.39Rennin
CAS:Rennin or Chymosin, a stomach enzyme in some animals, curdles milk by cleaving K-casein; key in cheese making.Colore e forma:SolidSphingolipid ceramide N-deacylase (SCDase)
CAS:SCDase splits fatty acids from sphingosine in glycosphingolipids, forming lysoglycosphingolipids.Colore e forma:SolidBilirubin oxidase
CAS:Bilirubin oxidase (BOD), a multi-copper enzyme, converts bilirubin to biliverdin, reduces O2 to H2O, and aids porphyrin metabolism.Colore e forma:SolidDiadenosine pentaphosphate pentaammonium
CAS:Endogenous vasoactive dinucleotide isolated from thrombocytes; found in secretory vesicles across various cells.Formula:C20H44N15O22P5Colore e forma:SolidPeso molecolare:1001.524Fluazifop-P-butyl
CAS:Fluazifop-P-butyl is an arylophenoxypropionate group graminicide that functions as an inhibitor of acetyl-CoA carboxylase (ACCase)[1].Formula:C19H20F3NO4Colore e forma:Light Yellow LiquidPeso molecolare:383.361-Stearoyl-2-Adrenoyl-sn-glycero-3-PE
CAS:Phospholipid with stearic acid at sn-1, adrenic acid at sn-2; less in older human hippocampal mitochondria.Formula:C45H82NO8PColore e forma:SolidPeso molecolare:796.124TPT-004
TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuatingColore e forma:Odour SolidLaccase-IN-1
Laccase-IN-1 (compound 4b) is an orally active laccase inhibitor, demonstrating an IC50 of 11.3 μM.Formula:C16H19FN2O3Colore e forma:SolidPeso molecolare:306.332'-Rhamnoechinacoside
CAS:2'-Rhamnoechinacoside is a naturally occurring compound sourced from Cistanche tubulosa.Formula:C41H56O24Colore e forma:SolidPeso molecolare:932.92H-Cho-Arg (trifluoroacetate salt)
CAS:2H-Cho-Arg, a cationic lipid, enables gene delivery into cells and shows cytotoxicity at 92.7 μg/ml.Formula:C43H73F6N5O7Colore e forma:SolidPeso molecolare:886.06DIPQUO hydrochloride
DIPQUO hydrochloride: ALP activator (EC50=6.27μM, C2C12 cells), induces osteoblast differentiation via p38 MAPK-β.Formula:C20H18ClN3OPurezza:98.09%Colore e forma:SoildPeso molecolare:351.83Ref: TM-T11048L
1mg49,00€5mg87,00€10mg131,00€25mg198,00€50mg276,00€100mg380,00€200mg513,00€1mL*10mM (DMSO)87,00€PDE4-IN-3
CAS:PDE4-IN-3, a new oral drug, potently blocks PDE4 enzyme with 4.2 nM IC50.Formula:C35H33FO8Colore e forma:SolidPeso molecolare:600.639RARα antagonist 1
Compound 21, an orally active and selective RARα antagonist, exhibits a potent inhibition of the retinoic acid receptor α with an IC50 of 4.6 nM [1].Formula:C26H23NO4Colore e forma:SolidPeso molecolare:413.47HBPC-GSH
CAS:HBPC-GSH, a derivative of glutathione, functions as an inhibitor for the glyoxalase system, specifically inhibiting cGloI and cGloII with IC50 values of 0.6μMFormula:C17H23BrN4O8SColore e forma:SolidPeso molecolare:523.36MEY-003
MEY-003, an Autotaxin (ATX) inhibitor, exhibits EC50 values of 460 nM for hATX-β and 1.09 μM for hATX-ɣ (analysis with LPC18:1), demonstrating its potencyColore e forma:Odour SolidN-Desmethyl imatinib mesylate
CAS:Norimatinib mesylate, N-Desmethyl imatinib metabolite, inhibits v-Abl, c-Kit, PDGFR.Formula:C29H33N7O4SColore e forma:SolidPeso molecolare:575.68Febuxostat n-butyl isomer
CAS:Febuxostat n-butyl isomer is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .Formula:C16H16N2O3SColore e forma:SolidPeso molecolare:316.38VU533
CAS:VU533 is a NAPE-PLD activator, EC50=0.30 µM, boosts macrophage activity, potential in cardiometabolic diseases.Formula:C21H22FN3O3S2Purezza:99.87%Colore e forma:SolidPeso molecolare:447.55VU534
CAS:VU534 is a NAPE-PLD agonist with an EC50 of 0.30 μM.VU534 is a dual inhibitor of FAAH and sEH, with an IC50 of 1.2 μM for sEH.VU534 is used in diseases relatedFormula:C21H22FN3O3S2Purezza:98.85%Colore e forma:SolidPeso molecolare:447.55(R)-ICMT-IN-3
(R)-ICMT-IN-3 (compound ent 2-27) functions as a potent inhibitor of ICMT, exhibiting an IC50 value of 0.01 μM [1].Colore e forma:Odour SolidDiorcinol
CAS:Diorcinol is a natural product that can be used as a reference standard. The CAS number of Diorcinol is 20282-75-1.Formula:C14H14O3Colore e forma:SolidPeso molecolare:230.263FCE 28073
CAS:FCE 28073 is a Monoamine oxidase B inibitor with IC50 of 0.45 uM.Formula:C17H19FN2O2Purezza:99.92%Colore e forma:SolidPeso molecolare:302.34Ellagic acid 4-O-β-D-xylopyranoside
CAS:Ellagic acid 4-O-β-D-xylopyranoside, an ellagitannin found naturally, exhibits antimicrobial properties and acts as an inhibitor of xanthine oxidase, displayingFormula:C19H14O12Colore e forma:SolidPeso molecolare:434.31Carbolactone
CAS:Carbolactone is a biologically active metabolite from fungi [1] .Formula:C24H36O3Colore e forma:SolidPeso molecolare:372.54Diadenosine pentaphosphate pentasodium
CAS:Diadenosine pentaphosphate pentasodium, an endogenous purine from platelets and various cells, has vasoactive properties.Formula:C20H24N10Na5O22P5Colore e forma:SolidPeso molecolare:1026.28Malate dehydrogenase
CAS:Malate dehydrogenase catalyzes the mutual conversion of oxaloacetate and malate, and is associated with the oxidation/reduction of dinucleotide coenzymes [1] .Colore e forma:SolidMK-8262
CAS:MK-8262: oral CETP inhibitor, potent (IC50 = 53 nM, log D = 5.3), may impact HDL/LDL and CHD research.Formula:C35H25F9N2O5Colore e forma:SolidPeso molecolare:724.58Caffeoylcalleryanin
CAS:Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.Formula:C22H24O11Colore e forma:SolidPeso molecolare:464.4H-Gly-Pro-Gly-NH2
CAS:<p>H-Gly-Pro-Gly-NH2, a tripeptide, inhibits HIV-1 and HIV-2 replication (EC50: 35µM, 30µM) by blocking capsid formation.</p>Formula:C9H16N4O3Colore e forma:SolidPeso molecolare:228.25Teprotide
CAS:Teprotide is an angiotensin-converting enzyme (ACE) inhibitor used to study hypertensive [1].Formula:C53H76N14O12Colore e forma:SolidPeso molecolare:1101.26Dansylphenylalanine
CAS:Dansylphenylalanine is a typical fluorescent analyte.Formula:C21H22N2O4SColore e forma:SolidPeso molecolare:398.48PKCζ/ι pseudosubstrate inhibitor
CAS:PKCζ/ι pseudosubstrate inhibitor demonstrates comprehensive inhibitory activity across the protein kinase C (PKC) family and is associated with the induction ofFormula:C76H128N30O16Colore e forma:SolidPeso molecolare:1718.02Casein kinase 1δ-IN-15
CAS:Casein kinase 1δ-IN-15, an inhibitor for casein kinase 1 (CK1δ), exhibits an IC50 of 0.045 μM [1].Formula:C19H17FN6OColore e forma:SolidPeso molecolare:364.38Methoxycarbonyl-D-Nle-Gly-Arg-pNA
CAS:Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin substrate utilized for coagulation factors IXa (FIXa) and Xa (FXa), as evidenced by studies [1] [2] [3Formula:C22H34N8O7Colore e forma:SolidPeso molecolare:522.55Cyclosporin A-Derivative 3
CAS:Cyclosporin A-Derivative 3 is a derivative of Cyclosporin A with calcineurin inhibition [1] .Formula:C63H111N11O12Colore e forma:SolidPeso molecolare:1214.6213C C16 Sphingomyelin (d18:1/16:0)
CAS:'13C-enriched C16 Sphingomyelin is a standard for quantifying C16 sphingomyelin by MS. Common in eggs; less in brain/milk; interacts with cholesterol.'Formula:C39H79N2O6PColore e forma:SolidPeso molecolare:704.035α-Glucosidase-IN-87
α-Glucosidase-IN-87 (Compound 11c) is an orally active inhibitor of α-glucosidase with an IC50 of 119.7 μM. It exhibits hypoglycemic properties and is applicable in research on metabolic diseases such as diabetes.Colore e forma:Odour SolidH-Pro-Phe-OH
CAS:H-Pro-Phe-OH is a dipeptide formed from proline and phenylalanine, serving as a substrate for prolylase and in peptide synthesis.Formula:C14H18N2O3Colore e forma:SolidPeso molecolare:262.30IETP2
CAS:IETP2 targets low-density lipoprotein receptor-related protein 1 (LRP1) with a KD of 738 nM, making it useful for delivering drugs and imaging agents across the blood-labyrinth barrier (BLB).Formula:C107H171N39O29Colore e forma:SolidPeso molecolare:2467.75Fmoc-Ile-Ser(psi(Me,Me)pro)-OH
CAS:Fmoc-Ile-Ser(psi(Me,Me)pro)-OH is a dipeptide.Formula:C27H32N2O6Colore e forma:SolidPeso molecolare:480.55α-Glucosidase-IN-54
CAS:α-Glucosidase-IN-54 (compound 2) functions as an α-glucosidase inhibitor, exhibiting an IC 50 value of 0.011 mM, and is derived from Syzygium jambos (L.). This compound is employed in diabetes research [1].Formula:C24H36O3Colore e forma:SolidPeso molecolare:372.54HLF1-11
CAS:HLF1-11: human lactoferrin peptide, antimicrobial, inhibits MPO, steers monocytes to macrophages, boosts immunity.Formula:C56H95N25O14SColore e forma:SolidPeso molecolare:1374.58N,S-Bis-Fmoc-Glutathione
CAS:N,S-Bis-Fmoc-Glutathione is a potent inhibitor of glyoxalase II, exhibiting a K i of 0.32 mM [1].Formula:C40H37N3O10SColore e forma:SolidPeso molecolare:751.8Methionylserine
CAS:Methionylserine (H-MET-SER-OH), a dipeptide, binds hPEPT1 (Km 0.2 mM), inhibits ACE, used in hypertension research.Formula:C8H16N2O4SColore e forma:SolidPeso molecolare:236.29Tianeptine Metabolite MC5 sodium
CAS:Tianeptine metabolite MC5, an active derivative of the atypical antidepressant tianeptine produced through β-oxidation, exhibits selective G protein activationFormula:C19H20ClN2O4S·NaColore e forma:SolidPeso molecolare:430.88Glycyllysine
CAS:<p>Glycyllysine is a dipeptide. It can be used to study the interactions of the lysine side chain with copper in Glycyl-L-lysine-copper(II) complex.</p>Formula:C8H17N3O3Colore e forma:SolidPeso molecolare:203.24SHP2-IN-37
SHP2-IN-37 (compound C5) is a potent allosteric inhibitor selective for SHP2, with an IC50 of 0.023 μM. It exhibits antiproliferative effects on KYSE-520 and MV-411 cells, with IC50 values of 6.97 μM and 0.67 μM, respectively.Formula:C19H22Cl2N4O2SColore e forma:SolidPeso molecolare:440.084053-Oxocholic acid
CAS:3-Oxocholic acid(3-Ketocholic acid) is the metabolite of bile acid and the main product of bile degradation by Clostridium perfringens in the intestine.3-Formula:C24H38O5Purezza:99.44%Colore e forma:SolidPeso molecolare:406.56Ref: TM-T19124
1mg44,00€5mg93,00€10mg126,00€25mg203,00€50mg303,00€100mg442,00€200mg642,00€1mL*10mM (DMSO)92,00€Zabicipril HCl
CAS:Zabicipril HCl（S 9650） is a potent angiotensin-converting enzyme inhibitor.Formula:C23H33ClN2O5Purezza:99.24%Colore e forma:SoildPeso molecolare:452.9711β-HSD1 inibitor 17
CAS:11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).Formula:C22H20F3N3O2SPurezza:99.26% - 99.72%Colore e forma:SoildPeso molecolare:447.47Dimethylaminomicheliolide HCl
CAS:Dimethylaminomicheliolide HCl has potential anti-inflammatory and anti-tumor activity and inhibits the proliferation of glioblastoma cells by targeting pyruvateFormula:C17H28ClNO3Purezza:99.91%Colore e forma:SoildPeso molecolare:329.86Nicotinic Acid Adenine Dinucleotide
CAS:Nicotinic Acid Adenine Dinucleotide is a precursor of NAD (Nicotinamide adenine dinucleotide) and a substrate for glutamine-dependent NAD+ synthaseFormula:C21H26N6O15P2Colore e forma:SoildPeso molecolare:664.41VH4127
VH4127 is a cyclic peptide designed to target low-density lipoprotein receptors (LDLR) with a KD of 18 nM for hLDLR. Incorporating non-natural amino acid residues, VH4127 binds specifically to epidermal growth factor (EGF) LDLR homologous domains in both rodents and humans.Formula:C41H73N15O9S4Colore e forma:SolidPeso molecolare:1048.37D-3
CAS:D-3, a phosphorpeptide, is an efficient, simple, and specific iPSC-eliminating agent.Formula:C48H47N4O10PColore e forma:SolidPeso molecolare:870.896GSK-3β/CK-1δ-IN-1
GSK-3β/CK-1δ-IN-1 (8d) is a dual inhibitor of GSK-3β and CK-1δ that can cross the blood-brain barrier, with IC50 values of 0.77 μM and 0.57 μM, respectively. GSK-3β/CK-1δ-IN-1 (8d) is applicable in neuroblastoma research.Formula:C22H17F3N4OColore e forma:SolidPeso molecolare:410.39PKM2-IN-10
PKM2-IN-10 is a PKM2 inhibitor. It effectively suppresses the proliferation of A549 and HCC1833 cell lines with IC50 values of 3.36 μM and 9.20 μM, respectively. PKM2-IN-10 demonstrates antitumor activity in human non-small cell lung cancer (NSCLC) and mouse lung adenocarcinoma models. It is applicable for research in lung cancer.Formula:C21H15F4N5Colore e forma:SolidPeso molecolare:413.12636Ethyl gentisate
CAS:Ethyl gentisate acts as a dual regulator of cell differentiation, promoting osteoblast differentiation while inhibiting osteoclast differentiation.Formula:C9H10O4Purezza:99.55%Colore e forma:SolidPeso molecolare:182.17IDO1/TDO-IN-8
IDO1/TDO-IN-8 (Compound CZ-17) is a dual IDO1 and TDO inhibitor capable of crossing the blood-brain barrier, with EC50 values of 0.33 μM and 1.78 μM, respectively. It modulates the kynurenine pathway of tryptophan metabolism, reducing the kynurenine/tryptophan ratio. IDO1/TDO-IN-8 has neuroprotective effects, alleviating motor dysfunction and improving depressive behavior, making it relevant for research into Parkinson's disease with comorbid depression.Formula:C17H14N2SColore e forma:SolidPeso molecolare:278.37
