Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5592 produtos de "Apoptose"
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Bax inhibitor peptide V5 acetate
<p>Bax inhibitor peptide V5 acetate (Bax inhibitor peptide V5 acetate（579492-81-2 free base)) is a Bax-mediated apoptosis inhibitor, used for cancer treatment.</p>Fórmula:C29H54N6O8SPureza:99.2%Cor e Forma:SolidPeso molecular:646.85Conatumumab
CAS:<p>Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).</p>Pureza:> 95% - > 95%Cor e Forma:LiquidPeso molecular:145 kDa (average)Ref: IN-DA006YB9
1gA consultar1mg50,00€5mg52,00€10mg68,00€25mg129,00€50mg150,00€100mg163,00€250mg555,00€Pravastatin sodium
CAS:<p>Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.</p>Fórmula:C23H35NaO7Pureza:97.14%Cor e Forma:White Crystalline PowderPeso molecular:446.52Xanthone
CAS:<p>Xanthone (Xanthenone) is currently used as ovicide for codling moth eggs and as a larvicide.</p>Fórmula:C13H8O2Pureza:99.44% - 99.86%Cor e Forma:Off-White PowderPeso molecular:196.2AZD7624
CAS:<p>AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.</p>Fórmula:C27H30FN5O3Pureza:98.82%Cor e Forma:SolidPeso molecular:491.56L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-
CAS:Fórmula:C26H41N3O5Pureza:98%Cor e Forma:SolidPeso molecular:475.6208BETd-260
CAS:<p>BETd-260, a PROTAC linked by a Cereblon ligand and a BET ligand, has an inhibitory effect on BRD4 protein in leukemic cell lines.</p>Fórmula:C43H46N10O6Pureza:96.76%Cor e Forma:SolidPeso molecular:798.89Oxybenzone
CAS:<p>Oxybenzone (Eusolex 4360) is an organic compound used in sunscreens. It is a derivative of benzophenone.</p>Fórmula:C14H12O3Pureza:99.70%Cor e Forma:Colorless Crystals Physical Description White To Off-White Or Light Yellow Powder (Ntp 1992)Peso molecular:228.24Flurbiprofen
CAS:<p>Flurbiprofen is an anti-inflammatory, analgesic, antipyretic that reduces bone resorption by inhibiting carbonic anhydrase.</p>Fórmula:C15H13FO2Pureza:99.78% - 99.96%Cor e Forma:SolidPeso molecular:244.2609Capecitabine
CAS:<p>Capecitabine is a prodrug in the antimetabolite class, transformed into cytotoxic 5-FU by tumor cells, inhibiting DNA and RNA synthesis.</p>Fórmula:C15H22FN3O6Pureza:99.81% - >99.99%Cor e Forma:Less Solid Colourless SolidPeso molecular:359.35Aminoguanidine hydrochloride
CAS:<p>Aminoguanidine hydrochloride (Hydrazinecarboximidamide) is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy.</p>Fórmula:CH6N4·HClPureza:99.80%Cor e Forma:White To Off-White SolidPeso molecular:110.55Nitroaspirin
CAS:<p>NCX 4016, a NO-donor nitro-derivative of Aspirin, inhibits COX-1 and triggers apoptosis in ovarian cancer cells by modulating EGFR/PI3K/STAT3 and Bcl-2.</p>Fórmula:C16H13NO7Pureza:99.32%Cor e Forma:SolidPeso molecular:331.28Dasatinib monohydrate
CAS:<p>Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.</p>Fórmula:C22H28ClN7O3SPureza:99.68% - >99.99%Cor e Forma:SolidPeso molecular:506.03Methyl 3,4-dihydroxybenzoate
CAS:<p>Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester) is a major metabolite of antioxidant polyphenols found in green tea.</p>Fórmula:C8H8O4Pureza:98.51% - >99.99%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:168.15Methazolamide
CAS:<p>Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.</p>Fórmula:C5H8N4O3S2Pureza:99.31% - 99.77%Cor e Forma:Crystals From Water SolidPeso molecular:236.27Nortriptyline hydrochloride
CAS:<p>Nortriptyline HCl, a metabolite of amitriptyline, treats major and atypical depression, dysthymia.</p>Fórmula:C19H22ClNPureza:99.85% - ≥95%Cor e Forma:SolidPeso molecular:299.84Doxorubicin hydrochloride
CAS:<p>Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).</p>Fórmula:C27H29NO11·HClPureza:98% - 99.52%Cor e Forma:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Peso molecular:579.99Oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one, 2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-8-methylene-, (1aR,4E,7aS,10aS,10bR)-
CAS:Fórmula:C15H20O3Pureza:97%Cor e Forma:SolidPeso molecular:248.31751,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one
CAS:Fórmula:C16H10O7Pureza:98%Cor e Forma:SolidPeso molecular:314.2464Proparacaine hydrochloride
CAS:<p>Proparacaine Hydrochloride is the hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property.</p>Fórmula:C16H26N2O3·HClPureza:99.47% - 99.87%Cor e Forma:SolidPeso molecular:330.86β-Elemene
CAS:<p>β-Elemene (Levo-β-elemene) is a natural product isolated from Curcuma wenyujin, with an antitumor activity and induce cell apoptosis.</p>Fórmula:C15H24Pureza:99.165% - 99.35%Cor e Forma:SolidPeso molecular:204.35UC-514321
CAS:<p>UC-514321 directly targets STAT3/5 and represses TET1 expression.</p>Fórmula:C26H35NO5Pureza:98.50%Cor e Forma:SolidPeso molecular:441.56Carbaryl
CAS:<p>Carbaryl is a carbamate insecticide/parasiticide with low dermal toxicity used against head lice.</p>Fórmula:C12H11NO2Pureza:98.26% - 99.75%Cor e Forma:Colorless To Light Tan Crystals By Inhalation (Dust Etc ) Produces Toxic Oxides Of Nitrogen During CombustionPeso molecular:201.22Fenbufen
CAS:<p>Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis.</p>Fórmula:C16H14O3Pureza:98.35% - 98.46%Cor e Forma:White SolidPeso molecular:254.28Flubendazole
CAS:<p>Flubendazole (Flumoxane) is available OTC in Europe that is an anthelmintic using to treat worm infection in humans.</p>Fórmula:C16H12FN3O3Pureza:98.47% - 99.30%Cor e Forma:White To Pale Yellow PowderPeso molecular:313.28Methotrexate
CAS:<p>Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR.</p>Fórmula:C20H22N8O5Pureza:96.84% - 99.91%Cor e Forma:Orange-Brown Crystalline Powder Chemotherapy Drug That Interferes With Dna And Rna SynthesisPeso molecular:454.44Phenformin
CAS:<p>Phenformin: a biguanide with anti-cancer, anti-glycemic effects, inhibits skin tumors, enhances keratinocyte differentiation/apoptosis.</p>Fórmula:C10H15N5Pureza:99.72%Cor e Forma:SolidPeso molecular:205.26Nifuratel
CAS:<p>Nifuratel (SAP 113) is a local antiprotozoal and antifungal agent that may also be given orally.</p>Fórmula:C10H11N3O5SPureza:99.76% - 99.87%Cor e Forma:Fresh Yellow Crystalline Or Yellow PowderPeso molecular:285.28Benufutamab
CAS:<p>Benufutamab (GEN1029) is an agonistic antibody targeting death receptor 5 (DR5) with anti-tumor activity, used in the study of solid tumors.</p>Pureza:98.6% (SEC-HPLC) - 98.62% (SEC-HPLC)Cor e Forma:LiquidPioglitazone
CAS:<p>Pioglitazone (U 72107) is a selective and oral PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively . High-Quality, Low-Cost!</p>Fórmula:C19H20N2O3SPureza:95% - 99.57%Cor e Forma:White PowderPeso molecular:356.44Inavolisib
CAS:<p>Inavolisib (GDC-0077) is an orally available selective PI3Kα inhibitor with an IC50 value of 0.038 nM.Cost-effective and quality-assured.</p>Fórmula:C18H19F2N5O4Pureza:97.36% - 99.87%Cor e Forma:SolidPeso molecular:407.37Ligandrol
CAS:<p>Ligandrol is a novel nonsteroidal, oral SARM that binds to the androgen receptor with high affinity (Ki: 1 nM) and selectivity.</p>Fórmula:C14H12F6N2OPureza:99.94% - >99.99%Cor e Forma:SolidPeso molecular:338.25Stachyose tetrahydrate
CAS:<p>Stachyose tetrahydrate (D-Stachyose tetrahydrate) is a tetrasaccharide consisting of two α-D-galactose units, one α-D-glucose unit, and one β-D-fructose unit</p>Fórmula:C24H50O25Pureza:99.89%Cor e Forma:White To Off White Crystalline PowderPeso molecular:738.64Geniposidic Acid
CAS:<p>Geniposidic acid, an iridoid glucoside, used in therapy of jaundice, inflammation and hepatic disorders.</p>Fórmula:C16H22O10Pureza:99.77% - >99.99%Cor e Forma:SolidPeso molecular:374.34Duvakitug
CAS:<p>Duvakitug (SAR-447189) is a humanized IgG1-λ2 monoclonal antibody targeting TNFSF15/TL1A, which can be used to study ulcerative colitis and Crohn's disease.</p>Pureza:SDS-PAGE:>95%;SEC-HPLC:96.17%Cor e Forma:LiquidPeso molecular:143.64 kDaβ-Carotene
CAS:<p>β-Carotene (Provitamin A) is a naturally-occurring retinol (vitamin A) precursor with potential antineoplastic and chemopreventive activities.</p>Fórmula:C40H56Pureza:98.84% - 99.83%Cor e Forma:Dark Red Power Or CrystalPeso molecular:536.87Sildenafil citrate
CAS:<p>Sildenafil citrate, a PDE5 inhibitor for erectile dysfunction and occasionally pulmonary hypertension.</p>Fórmula:C28H38N6O11SPureza:99.59% - 99.97%Cor e Forma:White SolidPeso molecular:666.70Avobenzone
CAS:<p>Avobenzone (Butyl methoxydibenzoylmethane), an oil-soluble ingredient, is a dibenzoylmethane derivative used in sunscreen products to absorb the full spectrum</p>Fórmula:C20H22O3Pureza:97.93%Cor e Forma:White To Pale Yellow SolidPeso molecular:310.39Bendamustine hydrochloride
CAS:<p>Bendamustine hydrochloride (EP-3101) (IC50 of 50 μM) is an alkylating agent associated with DNA damage.</p>Fórmula:C16H21Cl2N3O2·HClPureza:97.71%Cor e Forma:SolidPeso molecular:394.72CDDO-dhTFEA
CAS:<p>CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor.</p>Fórmula:C33H45F3N2O3Pureza:95.61% - 99.59%Cor e Forma:SolidPeso molecular:574.72Lercanidipine
CAS:<p>Lercanidipine (Masnidipine) is a calcium channel blocker of the dihydropyridine class.</p>Fórmula:C36H41N3O6Pureza:99.92%Cor e Forma:White To Light Yellow SolidPeso molecular:611.73Actarit
CAS:<p>Actarit (4-acetylaminophenylacetic acid) is an anti-inflammatory drug.</p>Fórmula:C10H11NO3Pureza:99.64% - 99.74%Cor e Forma:White Or Off-White Crystal Or Crystalline SolidPeso molecular:193.2Cusatuzumab
CAS:<p>Cusatuzumab (ARGX-110) is a human CD70 monoclonal antibody with enhanced antibody-dependent cytotoxic activity.</p>Pureza:95% - 95%Cor e Forma:LiquidLinagliptin
CAS:<p>Linagliptin (BI 1356) is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.</p>Fórmula:C25H28N8O2Pureza:99.15% - >99.99%Cor e Forma:SolidPeso molecular:472.54Epirubicin hydrochloride
CAS:<p>Epirubicin hydrochloride (Pharmorubicin) is a Topo and Foxp3 inhibitor. Epirubicin hydrochloride has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C27H30ClNO11Pureza:98.13% - 99.79%Cor e Forma:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Peso molecular:579.98Novobiocin Sodium
CAS:<p>Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound.</p>Fórmula:C31H35N2NaO11Pureza:99% - 99.28%Cor e Forma:SolidPeso molecular:634.61Mangiferin
CAS:<p>Mangiferin (Hedysarid) is used for antidiabetes. Extracted from Mangifera indica L.</p>Fórmula:C19H18O11Pureza:99.78% - 99.86%Cor e Forma:Light Yellow PowderPeso molecular:422.34CDKI-73
CAS:<p>CDKI-73: strong CDK9 blocker, Ki 4 nM, kills CLL cells selectively, aids cisplatin.</p>Fórmula:C15H15FN6O2S2Pureza:98.11%Cor e Forma:SolidPeso molecular:394.45Tetraethylenepentamine Pentahydrochloride
CAS:<p>Tetraethylenepentamine Pentahydrochloride is a high affinity copper and zinc chelator.</p>Fórmula:C8H23N5·5HClPureza:≥95%Cor e Forma:SolidPeso molecular:371.61Sunitinib Malate
CAS:<p>Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor.</p>Fórmula:C26H33FN4O7Pureza:98% - 99.26%Cor e Forma:SolidPeso molecular:532.56Tetrahydroxyquinone
CAS:<p>Tetrahydroxyquinone (Tetroquinone) is a primitive anticataract drug, is also a highly redox active molecule that can take part in a redox cycle.</p>Fórmula:C6H4O6Pureza:98.15%Cor e Forma:Penetrating Odor Black SolidPeso molecular:172.09Larotaxel
CAS:<p>Larotaxel (XRP9881), a taxane with anticancer properties, stabilizes microtubules, induces apoptosis, and is researched in breast and bladder cancer.</p>Fórmula:C45H53NO14Pureza:99.22%Cor e Forma:SolidPeso molecular:831.9Ciprofloxacin
CAS:<p>Ciprofloxacin (Bay-09867) mainly targets bacterial DNA Gyrase (IC50=0.22-0.31 µM) and topoisomerase IV (IC50=0.3-1.9 µM). antibiotic. High-Quality, Low-Cost!</p>Fórmula:C17H18FN3O3Pureza:98.77% - 99.91%Cor e Forma:White PowderPeso molecular:331.34Polyinosinic-polycytidylic acid sodium
CAS:<p>Polyinosinic-polycytidylic acid sodium (Poly(I:C) sodium) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and</p>Fórmula:(C10H13N4O8P)x·(C9H14N3O8P)x·xNaPureza:98%Cor e Forma:SolidPeso molecular:695.403HLY78
CAS:<p>HLY78, a Wnt/β-catenin activator, enhances Axin-LRP6 binding by targeting Axin's DIX domain.</p>Fórmula:C17H17NO2Pureza:99.548%Cor e Forma:SolidPeso molecular:267.32Ref: IN-DA00365L
1g285,00€5gA consultar10gA consultar1mg44,00€25gA consultar50gA consultar25mg68,00€50mg102,00€100mg120,00€250mg157,00€500mg184,00€Quinacrine dihydrochloride
CAS:<p>Quinacrine dihydrochloride (Mepacrine dihydrochloride) is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic</p>Fórmula:C23H30CLN3O·2HClPureza:98.24% - 99.80%Cor e Forma:Yellow Crystals Or PowderPeso molecular:472.88Ulocuplumab
CAS:<p>Ulocuplumab is a human anti-CXCR4 IgG4 antibody tackling AML, NHL, and multiple myeloma; induces CLL apoptosis.</p>Pureza:SDS-PAGE:97.2%;SEC-HPLC:96.2%Cor e Forma:LiquidPeso molecular:146.23 kDaNVS-ZP7-4
CAS:<p>NVS-ZP7-4 is a inhibitor of Zinc transporter SLC39A7 (ZIP7).</p>Fórmula:C28H28FN5OSPureza:99.86%Cor e Forma:SolidPeso molecular:501.625-Fluorouracil
CAS:<p>5-Fluorouracil (5-FU) is a uracil analog, an inhibitor of DNA synthesis.</p>Fórmula:C4H3FN2O2Pureza:98% - >99.99%Cor e Forma:White To Practically White Crystalline Powder Neoplastic Drug Chemosterilant For Insects (Epa 1998)Peso molecular:130.08Oxaprozin
CAS:<p>Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug.</p>Fórmula:C18H15NO3Pureza:98.53%Cor e Forma:SolidPeso molecular:293.32Sodium 4-phenylbutyrate
CAS:<p>Sodium 4-phenylbutyrate (TriButyrate), a transcriptional regulator, reversibly inhibits class I and II HDACs resulting in a global increase in gene expression.</p>Fórmula:C10H11NaO2Pureza:99.02% - >99.99%Cor e Forma:SolidPeso molecular:186.18Genistin
CAS:<p>Genistin (Genistoside) is the major isoflavonoid of soybeans and soy products.It has been reported to possess various therapeutic effects, including anti-</p>Fórmula:C21H20O10Pureza:97.65% - 97.85%Cor e Forma:Colorless CrystalsPeso molecular:432.38STAT3-IN-1
CAS:<p>STAT3-IN-1 selective and orally active inhibitor of STAT3(in HT29 and MDA-MB 231 cells, with IC50 values of 1.82 μM and 2.14 μM , respectively), induces tumor</p>Fórmula:C28H29NO6Pureza:95.89% - 95.89%Cor e Forma:SolidPeso molecular:475.534H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-
CAS:Fórmula:C27H30O10Pureza:98%Cor e Forma:SolidPeso molecular:514.5211BAM 15
CAS:<p>BAM 15 is an uncoupler of mitochondrial protonophore.</p>Fórmula:C16H10F2N6OPureza:99.75% - 99.92%Cor e Forma:SolidPeso molecular:340.29Disulfiram
CAS:<p>Disulfiram, a carbamate, deters alcohol use by blocking aldehyde dehydrogenase, causing unpleasant effects when alcohol is consumed.</p>Fórmula:C10H20N2S4Pureza:95.57% - 99.79%Cor e Forma:White To Off-White Crystalline Powder Unpleasant Taste With Metallic Or Garlic Aftertaste Ph Of A Solution Obtained By Shaking 1 G With 30Peso molecular:296.54Ifabotuzumab
CAS:<p>Ifabotuzumab (KB-004) is an antibody targeting EphA3+ cells, significantly reducing CCR10+ cells and improving pulmonary fibrosis in humanized NSG mice.</p>Pureza:>95%Cor e Forma:LiquidEzabenlimab
CAS:<p>Ezabenlimab (BI-754091) is an anti-PD-1 mAb, Kd 6 nM, blocks PD-1/PD-Ls, boosts T-cell IFN-γ, inhibits tumors in vivo.</p>Pureza:99.1% (SDS-PAGE); 96.9% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.9% (SEC-HPLC)Cor e Forma:LiquidJQAD1
CAS:<p>JQAD1, a potent EP300 degrader (DC50≤31.6 nM), induces apoptosis, suppresses tumor growth, and selectively downregulates CRC and MYCN without affecting CBP.</p>Fórmula:C48H52F4N6O9Pureza:99.75%Cor e Forma:SolidPeso molecular:932.95Penpulimab
CAS:<p>Penpulimab is a monoclonal antibody targeting PD-1 with antitumor activity, used in studies of pancreatic cancer.</p>Pureza:96.8% (SEC-HPLC) - 96.8% (SEC-HPLC)Cor e Forma:LiquidYS-67
CAS:<p>YS-67 is an orally available, selective and potent EGFR inhibitor with antitumor activity, inhibits p-EGFR and p-AKT, and inhibits the proliferation of A549, PC-9, and A431 cells.YS-67 blocks cell cycle progression and induces apoptosis in the G0/G1 phase, and can be used in the study of non-small-cell lung cancer.</p>Fórmula:C32H34N4O3Pureza:98.88%Cor e Forma:SoildPeso molecular:522.64Fenobam
CAS:<p>Fenobam shows inverse agonist activity which blocks the mGlu5 receptor basal activity(IC50: 84 nM).</p>Fórmula:C11H11ClN4O2Pureza:99.93%Cor e Forma:SolidPeso molecular:266.68Perindopril erbumine
CAS:<p>Perindopril erbumine is a non-sulfhydryl ACE inhibitor that reduces blood pressure and increases urine sodium.</p>Fórmula:C23H43N3O5Pureza:99.23% - 99.75%Cor e Forma:White SolidPeso molecular:441.61Ibuprofen
CAS:<p>Ibuprofen, an NSAID, reduces pain, inflammation, and fever by limiting prostaglandin production.</p>Fórmula:C13H18O2Pureza:99.7% - 99.81%Cor e Forma:Colorless Solid CrystallinePeso molecular:206.28Maprotiline hydrochloride
CAS:<p>Maprotiline hydrochloride (Psymion) is a tetracyclic antidepressant akin to tricyclics with similar side effects.</p>Fórmula:C20H24ClNPureza:99.68% - 99.84%Cor e Forma:White PowderPeso molecular:313.864BFC1108
CAS:<p>BFC1108 targets Bcl-2 and converts it to a pro-apoptotic protein, inhibits the growth of triple-negative breast cancer xenografts with high Bcl-2 expression, inhibits breast cancer lung metastasis, and induces apoptosis of Bcl-2-expressing cancer cells.</p>Fórmula:C23H21ClN2O4Pureza:98.50%Cor e Forma:SoildPeso molecular:424.88S55746
CAS:<p>S55746 (BLC201) is an effective and selective BCL-2 inhibitor (Ki: 1.3 nM and a Kd of 3.9 nM).</p>Fórmula:C43H42N4O6Pureza:97.14%Cor e Forma:SolidPeso molecular:710.82SD-36 TFA
<p>SD-36 TFA is a selective and highly efficient STAT3 degrader with a Kd value of about 50 nM.SD-36 has anticancer and antitumor activity, and can break down mutant STAT3 proteins in cells and inhibit STAT3 transcription.SD-36 promotes growth inhibition and induces apoptosis through inhibition of Mcl-1 in gliomas.</p>Fórmula:C61H63F5N9O14PPureza:98.43% - >99.99%Cor e Forma:SolidPeso molecular:1272.17Bisindolylmaleimide VIII acetate
CAS:<p>Bisindolylmaleimide VIII acetate is a selective PKC inhibitor with an IC50 of 158 nM in rat brain and varying IC50s for different PKC isoforms.</p>Fórmula:C26H26N4O4Pureza:99.27%Cor e Forma:SolidPeso molecular:458.51Sodium etidronate
CAS:<p>Sodium etidronate (Didronel), a bisphosphonate, resists degradation, inhibits osteoclasts, and may boost bone formation.</p>Fórmula:C2H6Na2O7P2Pureza:99.5% - 99.75%Cor e Forma:LiquidPeso molecular:249.99S-allyl-L-cysteine
CAS:<p>S-allyl-L-cysteine (S-Allylcysteine), a natural constituent of fresh garlic, has antioxidant and anticancer properties in animals.</p>Fórmula:C6H11NO2SPureza:97.84% - 99.87%Cor e Forma:SolidPeso molecular:161.22Tubulin inhibitor 35
CAS:<p>Tubulin inhibitor 35 (Tubulin IN 35) is a topoisomerase I and microtubulin polymerization inhibitor with antitumor activity and induces apoptosis .</p>Fórmula:C21H21N3OPureza:99.45%Cor e Forma:SoildPeso molecular:331.41Spartalizumab
CAS:<p>"Spartalizumab (PDR001), a humanized IgG4 monoclonal antibody, targets PD-1 to inhibit PD-L1/L2 interactions, useful in ATC research."</p>Pureza:SDS-PAGE:95.2%;SEC-HPLC:96.3%Cor e Forma:LiquidPeso molecular:145.74 kDaChlorzoxazone
CAS:<p>Chlorzoxazone (Chlorzoxazon) is a Muscle Relaxant. The physiologic effect of chlorzoxazone is by means of Centrally-mediated Muscle Relaxation.</p>Fórmula:C7H4ClNO2Pureza:99.49% - 99.6%Cor e Forma:SolidPeso molecular:169.57Amrinone
CAS:<p>Amrinone (Inocor) is a positive inotropic cardiotonic (cardiotonic agent) with vasodilator properties, phosphodiesterase 3 inhibitory activity.</p>Fórmula:C10H9N3OPureza:98.88% - 99.45%Cor e Forma:SolidPeso molecular:187.2Metronidazole
CAS:<p>Metronidazole (Metronidazol) is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.</p>Fórmula:C6H9N3O3Pureza:99.46% - 99.96%Cor e Forma:Cream-Colored CrystalsPeso molecular:171.15Metformin hydrochloride
CAS:<p>Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) is an AMPK activator. Metformin is used in type 2 diabetes research. Cost-effective and quality-assured.</p>Fórmula:C4H12ClN5Pureza:97.53% - 99.97%Cor e Forma:White Or Almost White Crystals Solid CrystallinePeso molecular:165.634-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole
CAS:Fórmula:C21H16FN3OSPureza:98%Cor e Forma:SolidPeso molecular:377.4346Sonrotoclax TFA
<p>Sonrotoclax TFA is an orally available and highly potent and selective Bcl-2 inhibitor of WT and G101V mutants with antitumor activity for the study of hematologic malignancies.</p>Fórmula:C51H60F3N7O9SPureza:99.63%Cor e Forma:SolidPeso molecular:1004.12Sulindac
CAS:<p>Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.</p>Fórmula:C20H17FO3SPureza:99.09% - 99.15%Cor e Forma:Yellow SolidPeso molecular:356.41Hydralazine hydrochloride
CAS:<p>Hydralazine hydrochloride, an antihypertensive phthalazine, induces vasodilation and may inhibit tumor DNA methylation.</p>Fórmula:C8H9ClN4Pureza:99.85% - 99.86%Cor e Forma:Yellow Crystals White Crystalline SolidPeso molecular:196.64Primidone
CAS:<p>Primidone (NCI-C56360) is a potent anticonvulsant agent.</p>Fórmula:C12H14N2O2Pureza:99.91%Cor e Forma:Crystals (Ntp 1992)Peso molecular:218.25Alexidine dihydrochloride
CAS:<p>Alexidine dihydrochloride: antifungal, antibiofilm, targets PTPMT1 for mitochondrial apoptosis, potential cancer treatment.</p>Fórmula:C26H58Cl2N10Pureza:99.32% - 99.81%Cor e Forma:SolidPeso molecular:581.71(R)-CR8
CAS:<p>(R)-CR8 ((R)-Isomer) is a potent and selective CDK inhibitor.</p>Fórmula:C24H29N7OPureza:98.41%Cor e Forma:SolidPeso molecular:431.53Tetrahydropalmatine
CAS:<p>Tetrahydropalmatine (DL-Tetrahydropalmatine) is an active component isolated from corydalis, suppressing amygdaloid release of dopamine to inhibit an epileptic</p>Fórmula:C21H25NO4Pureza:99.59% - 99.95%Cor e Forma:SolidPeso molecular:355.43Myricetin
CAS:<p>Myricetin (Cannabiscetin) is a natural flavonoid and MEK1 inhibitor. Myricetin has hypoglycemic and antioxidant activities. Cost-effective and quality-assured.</p>Fórmula:C15H10O8Pureza:97.92% - 99.85%Cor e Forma:Yellow Needles From Dilute Alcohol SolidPeso molecular:318.24Eragidomide
CAS:<p>Eragidomide (Cereblon modulator 1) is a CRBN E3 ligase modulator, specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.</p>Fórmula:C22H18ClF2N3O4Pureza:97.51% - 99.63%Cor e Forma:SolidPeso molecular:461.85Ketoprofen
CAS:<p>Ketoprofen (RP-19583) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects.</p>Fórmula:C16H14O3Pureza:99.67% - 99.97%Cor e Forma:SolidPeso molecular:254.28Milnacipran hydrochloride
CAS:<p>Milnacipran hydrochloride (Savella) is a serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders.</p>Fórmula:C15H23ClN2OPureza:99.7% - >99.99%Cor e Forma:White Crystalline PowderPeso molecular:282.81Fludarabine
CAS:<p>Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation.</p>Fórmula:C10H12FN5O4Pureza:99.65% - 99.89%Cor e Forma:White SolidPeso molecular:285.23Tamsulosin hydrochloride
CAS:<p>Tamsulosin hydrochloride (Flomax hydrochloride) is the hydrochloride salt of tamsulosin, a sulfonamide derivative with α1 adrenergic antagonist activity.</p>Fórmula:C20H29ClN2O5SPureza:95.45% - 99.95%Cor e Forma:White To Off-White SolidPeso molecular:444.97Olanzapine
CAS:<p>Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.</p>Fórmula:C17H20N4SPureza:99.86% - ≥95%Cor e Forma:Yellowish Crystalline PowderPeso molecular:312.43Lirentelimab
CAS:<p>Lirentelimab (AK002) is a humanized anti-Siglec-8 antibody that induces IL-5-activated apoptosis in eosinophils and inhibits IL-5-mediated mast cell activation.</p>Pureza:97.7% (SDS-PAGE); 99.7% (SEC-HPLC) - 97.7% (SDS-PAGE); 99.7% (SEC-HPLC)Cor e Forma:LiquidABT-510 acetate
CAS:<p>ABT-510 acetate: a TSP peptide mimicking anti-angiogenic, anti-inflammatory, and anti-cancer agent, inhibits tumor growth and angiogenesis in cancer and IBD.</p>Fórmula:C48H87N13O13Pureza:95.07%Cor e Forma:SolidPeso molecular:1054.28Fluvastatin sodium
CAS:<p>Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol</p>Fórmula:C24H25FNNaO4Pureza:98.54% - 99.56%Cor e Forma:Light Yellow Solid PowderPeso molecular:433.45Tolperisone hydrochloride
CAS:<p>Tolperisone hydrochloride (Muscalm) is a muscle relaxant for treating muscle tone disorders from neurological diseases.</p>Fórmula:C16H24ClNOPureza:99.51%Cor e Forma:White SolidPeso molecular:281.82Olsalazine disodium
CAS:<p>Olsalazine disodium (Dipentum) is bioconverted to 5-aminosalicylic acid (5-ASA) in the colon and has anti-inflammatory activity in ulcerative colitis.</p>Fórmula:C14H8N2Na2O6Pureza:99.47% - 99.52%Cor e Forma:Yellow Crystalline PowderPeso molecular:346.2Nortriptyline
CAS:<p>Nortriptyline is an antidepressant compound used for smoking cessation.</p>Fórmula:C19H21NPureza:99.8%Cor e Forma:SolidPeso molecular:263.381H-Benzimidazole, 5,6-dichloro-1-b-D-ribofuranosyl-
CAS:Fórmula:C12H12Cl2N2O4Pureza:98%Cor e Forma:SolidPeso molecular:319.14072(1H)-Pyridinone, 5,6-dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-
CAS:Fórmula:C17H19NO5Pureza:98%Cor e Forma:SolidPeso molecular:317.3365Ref: IN-DA002CWY
1g579,00€5gA consultar1mg30,00€5mg57,00€10mg65,00€25mg79,00€100mg116,00€250mg183,00€500mg240,00€Sodium butanoate
CAS:<p>Sodium butanoate (Sodium Butyrate) is the sodium salt of butyrate with potential antineoplastic activity.</p>Fórmula:C4H7NaO2Pureza:98.02% - 99.79%Cor e Forma:White PowderPeso molecular:110.09Batabulin
CAS:<p>Batabulin (T138067), an antitumor agent, binds selectively to β-tubulin, halts microtubule formation, and induces apoptosis.</p>Fórmula:C13H7F6NO3SPureza:99.85%Cor e Forma:SolidPeso molecular:371.26Minocycline hydrochloride
CAS:<p>Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.</p>Fórmula:C23H28ClN3O7Pureza:99.28% - >99.99%Cor e Forma:Bright Yellow-Orange Amorphous Solid Crystalline YellowPeso molecular:493.94Amcinonide
CAS:<p>Amcinonide (CL-34699) is a Corticosteroid. The mechanism of action of amcinonide is as a Corticosteroid Hormone Receptor Agonist.</p>Fórmula:C28H35FO7Pureza:98.33% - 99.62%Cor e Forma:SolidPeso molecular:502.57Belimumab
CAS:<p>Belimumab, a human IgG1λ monoclonal antibody, blocks BAFF, treating lupus and related fatigue.</p>Pureza:SDS-PAGE:98.4%;SEC-HPLC:98.4%Cor e Forma:LiquidPeso molecular:144.07 kDaRisedronic Acid
CAS:<p>Risedronic Acid (Risedronate), a pyridinyl biphosphonate, can inhibit osteoclast-mediated bone resorption.</p>Fórmula:C7H11NO7P2Pureza:99.85% - 99.87%Cor e Forma:White Crystalline PowderPeso molecular:283.11Onfekafusp alfa
CAS:<p>Onfekafusp alfa (L19TNF), a trimeric fusion of L19 scFv and human TNF, targets malignant glioma.</p>Cor e Forma:LiquidThalidomide-Piperazine-PEG3-NH2
CAS:<p>Thalidomide-Piperazine-PEG3-NH2: a cereblon ligand-linker for PROTAC E3 ligase recruitment.</p>Fórmula:C25H35N5O7Cor e Forma:SolidPeso molecular:517.583XIAP BIR2/BIR2-3 inhibitor-1
CAS:<p>XIAP BIR2/BIR2-3 inhibitor-1 (compound 3) serves as a potent dual inhibitor targeting BIR2 and BIR2-3 domains, with IC50 values of 1.9 nM and 0.8 nM, respectively. This compound is utilized in cancer research studies [1].</p>Fórmula:C72H96N16O14Cor e Forma:SolidPeso molecular:1409.63Disitertide
CAS:<p>Disitertide (P144) is an inhibitor of TGF-β1.</p>Fórmula:C68H109N17O22S2Pureza:98%Cor e Forma:SolidPeso molecular:1580.84Eciskafusp alfa
CAS:<p>Eciskafusp alfa, a cis-targeted IL2v immunocytokine, acts on programmed cell death 1 (PDCD1, commonly known as PD-1), preferentially targeting antigen-specific</p>Pureza:98%Cor e Forma:SolidPoly (I:C):Kanamycin (1:1)
<p>Poly (I:C):Kanamycin (1:1) is an equimolar mixture of Poly(I:C) and kanamycin. TLR3 agonist commonly used as a vaccine adjuvant; enhanced Poly(I:C) stability.</p>Cor e Forma:SolidMcl-1 inhibitor 15
<p>Mcl-1 Inhibitor 15 (Compound (Ra)-15), with a K i of 0.02 nM, is utilized in cancer research [1].</p>Fórmula:C40H42ClFN6O4SCor e Forma:SolidPeso molecular:757.32Pidilizumab
CAS:<p>Pidilizumab (CT-011), a humanized IgG1κ anti-PD-1 monoclonal antibody, serves as a DLL1 antagonist with potential applications in researching hematologic</p>Pureza:98%Cor e Forma:LiquidATPase-IN-3
CAS:<p>ATPase-IN-3 is an ATPase (ATPase) inhibitor that can be used in the study of metabolism-related diseases.</p>Fórmula:C10H6N2O3S2Pureza:97.76%Cor e Forma:SoildPeso molecular:266.3RET ligand-3
<p>RETligand-3 is the ligand for PROTAC QZ2135, which targets RET.</p>Fórmula:C38H42N10O3Cor e Forma:SolidPeso molecular:686.81Thalidomide-O-C8-Boc
CAS:<p>Thalidomide-O-C8-Boc: CRBN ligand for PROTAC creation, derived from Thalidomide.</p>Fórmula:C26H34N2O7Cor e Forma:SolidPeso molecular:486.565D-Trimannuronic acid
CAS:<p>D-Trimannuronic acid from seaweed induces TNF-α in mouse macrophages; useful in pain, dementia studies.</p>Fórmula:C18H26O19Cor e Forma:SolidPeso molecular:546.387Antibiotic DC 81
CAS:<p>DC 81: Streptomyces-derived antitumor antibiotic, potent nucleic acid synthesis inhibitor, binds DNA sequences, forms covalent adducts.</p>Fórmula:C13H14N2O3Cor e Forma:SolidPeso molecular:246.26p38-α MAPK-IN-8
<p>p38-α MAPK-IN-8 (Compound 13) is a lipophilic cationic derivative. It exhibits cytotoxicity toward various tumor cells, inducing cell cycle arrest and apoptosis, as well as increasing reactive oxygen species (ROS) production and causing mitochondrial membrane potential depolarization. Its antitumor activity may be related to the p38α MAPK pathway, making it a potential candidate for cancer research.</p>Fórmula:C49H62BrO4PCor e Forma:SolidPeso molecular:825.892PZ703b
CAS:<p>PZ703b is a novel BCL-XL PROTAC degrader with enhanced BCL-2 inhibition.</p>Fórmula:C80H102ClF3N10O11S4Cor e Forma:SolidPeso molecular:1600.44Ecdysone
CAS:<p>Ecdysone is a major steroid hormone in insects and herbs.</p>Fórmula:C27H44O6Pureza:99.22%Cor e Forma:PowderPeso molecular:464.63APG-1387
CAS:<p>APG-1387 inhibits IAPs, degrades cIAP1/2, XIAP, boosts chemosensitivity, and induces apoptosis in NPC.</p>Fórmula:C60H72N10O10S2Cor e Forma:SolidPeso molecular:1157.41ROCK/HDAC-IN-2
<p>ROCK/HDAC-IN-2 (Compound C-9) is a dual inhibitor of ROCK/HDAC, characterized by IC50 values of 0.185 µM for HDAC6, 0.8 µM for ROCK1, and 0.7 µM for ROCK2. It effectively induces apoptosis and mitochondrial membrane potential alterations in cancer cells and demonstrates notable antitumor activity, making it useful for research in pancreatic ductal adenocarcinoma (PDAC) and triple-negative breast cancer (TNBC).</p>Fórmula:C22H32N4O4SCor e Forma:SolidPeso molecular:448.58Cardanol (C15:1)
CAS:<p>Cardanol (C15:1), found in cashew nut shell liquid, induces mitochondria-associated apoptosis in human melanoma cells.</p>Fórmula:C21H34OPureza:98.48% - 99.77%Cor e Forma:SolidPeso molecular:302.49Se-Aspirin
CAS:<p>Se-Aspirin (Se-NSAID-8) has anticancer activity and gastroprotective effects, inhibits activation of proinflammatory and pro-survival NF-ĸB pathways, and inhibits the expression of anti-apoptotic targets downstream of NF-ĸB (e.g., Bcl-xL, Mcl-1, and survivin).Se-Aspirin induces Cell cycle arrest and activation of apoptosis accelerates ulcer healing and can be used to study pancreatic and colorectal cancer.</p>Fórmula:C12H12N2O3SePureza:98.07%Cor e Forma:SolidPeso molecular:311.2RO7567132
<p>RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.</p>Cor e Forma:Odour LiquidNF-κB-IN-19
<p>NF-κB-IN-19 (Compound 8) is an NF-κB inhibitor. It effectively induces DNA damage in tumor cells through the NF-κB signaling pathway and promotes the production of reactive oxygen species (ROS), as well as induces autophagy and apoptosis. Additionally, NF-κB-IN-19 inhibits levels of VEGF and HIF-1α, exerting antiproliferative effects in tumor cells through the PI3K/AKT and STAT-3 pathways. It is also effective in overcoming cisplatin resistance and exhibits antitumor activity.</p>Fórmula:C24H26Cl3F2N3O4PtCor e Forma:SolidPeso molecular:759.922-aminobenzo[d]thiazol-6-ol
CAS:<p>2-aminobenzo[d]thiazol-6-ol: antimicrobial, antioxidant, anticancer; may trigger cancer cell apoptosis.</p>Fórmula:C7H6N2OSPureza:98.27%Cor e Forma:SolidPeso molecular:166.2hCAIX-IN-23
<p>hCAIX-IN-23 (Compound 27) is a human carbonic anhydrase (hCA) inhibitor with Ki values of 10.4 nM for hCA IX and 8.5 nM for hCA XII. It not only inhibits hCA activity but also releases NO, exerting dual anti-tumor effects. By reducing the expression of hCA IX and iron regulatory proteins, hCAIX-IN-23 regulates mitochondrial caspase activity and the ferroptosis pathway, thereby inducing apoptosis. This compound is utilized in research focused on renal cancer.</p>Cor e Forma:Odour SolidG-Glu-Val
CAS:<p>G-Glu-Val (γ-glutamyl-L-valine, H-Glu-Val -OH), a flavour-regulating dipeptide, is a major contributor to "mellow".</p>Fórmula:C10H18N2O5Cor e Forma:SolidPeso molecular:246.26Lambertianic acid
CAS:<p>Lambertianic acid is a bioactive chemical that has anti-allergic and antibacterial effects.</p>Fórmula:C20H28O3Pureza:98%Cor e Forma:SolidPeso molecular:316.441PI3K/HDAC-IN-4
<p>PI3K/HDAC-IN-4 (Compound 31f) is a dual inhibitor targeting PI3K and HDAC, with an IC50 of 0.2μM. It demonstrates high selectivity for HDAC1-3, with IC50 values of 75.5 nM, 70.9 nM, and 1.9 nM, respectively. As a potent pan-PI3K inhibitor, PI3K/HDAC-IN-4 has IC50 values of 2.5 nM, 80.5 nM, 10.0 nM, and 57.2 nM for PI3Kα, β, δ, and γ, respectively. This compound effectively induces apoptosis in tumor cells by concurrently inhibiting the PI3K/AKT/mTOR signaling pathway and HDAC1-3. It shows significant antiproliferative activity across various tumor cell lines, such as MV4-11, Jeko-1, HL60, and MCF-7, with IC50 values of 0.2, 0.9, 0.8, and 1.5 μM, respectively. PI3K/HDAC-IN-4 is applicable in the study of lymphoma and leukemia.</p>Fórmula:C28H35F3N12O3Cor e Forma:SolidPeso molecular:644.29072Antitumor agent-100 hydrochloride
CAS:<p>Antitumor agent-100 hydrochloride (compound A6), serving as both an apoptosis inducer and molecular glue, exhibits superior anti-tumor activity [1].</p>Fórmula:C17H15Cl2N3OPureza:98%Cor e Forma:SolidPeso molecular:348.23Thalidomide-NH-PEG3-COOH
CAS:<p>Thalidomide-NH-PEG3-COOH is a cereblon-based E3 ligase ligand-linker for PROTAC synthesis.</p>Fórmula:C22H27N3O9Cor e Forma:SolidPeso molecular:477.47Bifenthrin
CAS:<p>Bifenthrin is a synthetic pyrethroid insecticide.Bifenthrin induces cell death in bovine mammary epithelial cells through ROS generation, disruption of calcium homeostasis, and alteration of the MAPK signaling cascade.Bifenthrin induces apoptosis by inducing cell-cycle arrest.</p>Fórmula:C23H22ClF3O2Pureza:99.25%Cor e Forma:SolidPeso molecular:422.87PROTAC SMARCA2/4 degrader-38
<p>PROTACSMARCA2/4 degrader-38 is a SMARCA2/4 PROTAC degrader with DC50 values of 3.0 nM and 4.0 nM, respectively. It facilitates the ubiquitination and degradation of SMARCA2/4 and can block the G0/G1 phase of the cell cycle, leading to the induction of apoptosis. PROTACSMARCA2/4 degrader-38 is applicable in acute myeloid leukemia (AML) research.</p>Cor e Forma:Odour SolidAnti-inflammatory agent 42
CAS:<p>Anti-inflammatory agent 42 has anti-inflammatory activity and inhibits the expression of TNF-α and IL-6 in LPS-stimulated macrophages.</p>Fórmula:C20H12N2OSPureza:98.13%Cor e Forma:SolidPeso molecular:328.39155H1
<p>155H1 (Compound 11) is a stapled peptide that covalently binds to hMcl1 (172-323) with an IC50 of 18 nM.</p>Fórmula:C79H120FN19O23SPeso molecular:1753.85092Pamrevlumab
CAS:<p>FG-3019 (Pamrevlumab), a human antibody, targets CTGF, potentially treating idiopathic pulmonary fibrosis.</p>Pureza:100% (SEC-HPLC) - 95%Cor e Forma:LiquidCholesteryl Hemisuccinate Tris Salt
CAS:<p>Cholesteryl Hemisuccinate Tris Salt is a cholesteryl ester with anticancer activity.Cholesteryl hemisuccinate has antitumor activity and inhibits tumor growth.</p>Fórmula:C35H61NO7Pureza:≥98%Cor e Forma:SolidPeso molecular:607.86HNPMI
CAS:<p>HNPMI is an epidermal growth factor receptor inhibitor that promotes apoptosis and is used in the study of colorectal cancer.</p>Fórmula:C22H20N2O3Pureza:97.19%Cor e Forma:SoildPeso molecular:360.41Sanggenon G
CAS:<p>Sanggenon G inhibits XIAP by binding its BIR3 domain; affinity is 34.26 μM, boosting caspase activation.</p>Fórmula:C40H38O11Cor e Forma:SolidPeso molecular:694.72MET/PDGFRA-IN-2
<p>MET/PDGFRA-IN-2 (compound 8h) serves as an inhibitor of MET and PDGFRA proteins, promoting apoptosis in cells and impeding the proliferation of MET-positive</p>Fórmula:C29H29N7OPureza:98%Cor e Forma:SolidPeso molecular:491.59cpm-1285
CAS:<p>CPM-1285 induces apoptosis by effectively inhibiting the function of intracellular Bcl-2 and associated death antagonists.</p>Fórmula:C153H240N44O42SPureza:98%Cor e Forma:SolidPeso molecular:3399.88TAT-NEP1-40
<p>TAT-NEP1-40, a blood-brain barrier (BBB) permeable peptide, confers protection to PC12 cells against oxygen and glucose deprivation (OGD) while promoting</p>Fórmula:C268H438N88O77Pureza:98%Cor e Forma:SolidPeso molecular:6124.89CPT2
CAS:<p>Carnitine palmitoyltransferase 2 (CPT2), an enzyme involved in fatty acid oxidation, serves as a prognostic biomarker for colorectal cancer (CRC).</p>Pureza:98%Cor e Forma:SolidTAT-BH4 (Bcl-xL)
<p>TAT-BH4 (Bcl-xL), primarily localized at the mitochondria, inhibits apoptotic cell death.</p>Fórmula:C159H268N58O45Pureza:98%Cor e Forma:SolidPeso molecular:3712.19Kurzipene D
CAS:<p>Kurzipene D: anticancer, induces apoptosis, halts HepG2 at S phase, anti-tumor in zebrafish, inhibits tumor growth and spread.</p>Fórmula:C26H36O8Cor e Forma:SolidPeso molecular:476.56Dehydrobruceine B
CAS:<p>Dehydrobruceine B, from Brucea javanica, enhances Cisplatin-induced apoptosis by affecting AIF, Bax, and Keap1-Nrf2.</p>Fórmula:C23H26O11Cor e Forma:SolidPeso molecular:478.45Anticancer agent 204
<p>Anticanceragent 204 (Compound 6) is a fluorinated derivative of cinnamamides with anticancer activity. It can arrest the cell cycle of HepG2 cells in the G1 phase and induces apoptosis by reducing mitochondrial membrane polarization (MMP) levels.</p>Fórmula:C26H18FN5O3SPeso molecular:499.11144ZMF-24
<p>ZMF-24 is an anti-triple-negative breast cancer (TNBC) agent that exhibits IC50 values of 0.22 μM and 0.44 μM against BT-549 and MDA-MB-231 TNBC cell proliferation, respectively. It targets the eukaryotic translation initiation factor 3 subunit D (EIF3D), disrupting TNBC's energy supply by inhibiting glycolysis. Additionally, ZMF-24 induces TNBC cell apoptosis (apoptosis) by stimulating sustained endoplasmic reticulum stress.</p>Cor e Forma:Odour SolidN-Stearoyltyrosine
CAS:<p>N-Stearoyltyrosine (N-(1-Oxooctadecyl)-L-tyrosine) is an analog of Anandamide. It exhibits neuroprotective effects by safeguarding the CA1 region of the hippocampus in a gerbil ischemia-reperfusion model. Additionally, N-Stearoyltyrosine inhibits free radical generation, enhances antioxidant capacity, and reduces IR-induced apoptosis (cell apoptosis).</p>Fórmula:C27H45NO4Cor e Forma:SolidPeso molecular:447.65c-Met/HDAC-IN-4
<p>c-Met/HDAC-IN-4, a dual inhibitor of c-Met/HDAC, exhibits an IC 50 value of 28.92 nM for c-Met. This compound effectively induces G 0 /G 1 phase cell cycle arrest and apoptosis in MDA-MB-231 breast cancer cells. Additionally, c-Met/HDAC-IN-4 suppresses both the proliferation and invasion of breast cancer cell lines.</p>Fórmula:C37H36N8OCor e Forma:SolidPeso molecular:608.73BCL-XL-IN-3
CAS:<p>BCL-XL-IN-3 (Compound 11) is an inhibitor of BCL-XL, with a Ki of less than 0.01 nM. It suppresses cell viability in both normal Molt-4 cells and digitonin-permeabilized Molt-4 cells, with EC50 values of 77.8 nM and 0.07 nM, respectively. BCL-XL-IN-3 can be utilized as an ADC toxin for synthesizing Clezutoclax.</p>Fórmula:C46H55N7O6SCor e Forma:SolidPeso molecular:834.045-LOX-IN-2
CAS:<p>5-LOX-in-2: a 5-lipoxygenase inhibitor with IC50 of 0.33 μM, reduces kidney cancer cell activity, induces apoptosis.</p>Fórmula:C17H16O4Pureza:98.74%Cor e Forma:SoildPeso molecular:284.31BRAFV600E/JNK-IN-1
<p>BRAFV600E/JNK-IN-1 (Compound 14c) is an inhibitor of JNK1, JNK2, JNK3, and BRAFV600E, with IC50 values of 0.51 μM, 0.53 μM, 1.02 μM, and 0.009 μM, respectively. It also inhibits the phosphorylation of MEK1/2 and ERK1/2. Additionally, BRAFV600E/JNK-IN-1 suppresses tumor cell proliferation, NO release, and PGE2 production, exhibiting both antitumor and anti-inflammatory activities.</p>Cor e Forma:Odour SolidPUMA BH3
<p>PUMA BH3 activates Bak, binds Bcl-2; triggers apoptosis via cytochrome C release; Kd 26 nM.</p>Fórmula:C128H202N42O43SPureza:98%Cor e Forma:SolidPeso molecular:3049.3Tilogotamab
CAS:<p>Tilogotamab (GEN-1029) is an agonistic hexameric complex targeting two independent epitopes on DR5, used for studying multiple myeloma (MM).</p>Pureza:95%Cor e Forma:LiquidsEH inhibitor-19
<p>sEH inhibitor-19 (Compound (R)-14i) is an orally active soluble epoxide hydrolase (sEH) inhibitor with an IC50 of 1.2 nM. This compound suppresses the expression of TNF-α and IL-6 and exhibits anti-inflammatory effects in mouse models of acute pancreatitis and Carrageenan-induced edema.</p>Fórmula:C28H28F3N3O4Cor e Forma:SolidPeso molecular:527.535PI3Kδ-IN-16
CAS:<p>PI3Kδ-IN-16 is a selective and potent PI3Kδ inhibitor with anticancer and antiproliferative activity, induces cell cycle arrest and apoptosis.</p>Fórmula:C22H26N6O2Pureza:99.68%Cor e Forma:SoildPeso molecular:406.48Thalidomide-O-PEG4-Boc
CAS:<p>Thalidomide-O-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].</p>Fórmula:C28H38N2O11Pureza:98%Cor e Forma:SolidPeso molecular:578.61TNF-α-IN-9
CAS:<p>TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.</p>Fórmula:C17H14O4Pureza:98.28%Cor e Forma:SoildPeso molecular:282.29Z-VDVA-(DL-Asp)-FMK
CAS:<p>Z-VDVA-(DL-Asp)-FMK is a derivative compound of Z-VDVAD-FMK specifically designed as an inhibitor targeting caspase-2.</p>Fórmula:C32H46FN5O11Cor e Forma:SolidPeso molecular:695.742VB-85247
<p>VB-85247 is a STING agonist that, by activating the STING pathway, induces the upregulation of inflammatory cytokines IFNα/β, TNFα, IL6, and CXCL10, as well as the maturation and activation of dendritic cells. It can lead to the regression of tumors within the bladder and is applicable in bladder cancer research.</p>Cor e Forma:Odour SolidHFY-4A
CAS:<p>HFY-4A is a novel HDAC inhibitor.HFY-4A has antitumour activity and has shown antiproliferative activity in breast cancer cells.</p>Fórmula:C20H19N3O2Pureza:98.66% - 99.22%Cor e Forma:SoildPeso molecular:333.38DiPT-4
<p>DiPT-4, a dual TOP1/PARP1 inhibitor, effectively induces DNA double-strand breaks (DSBs), cell cycle arrest, and apoptosis in cancer cells, with potential to</p>Fórmula:C32H22FN5O4SPureza:98%Cor e Forma:SolidPeso molecular:591.61Tasisulam sodium
CAS:<p>Tasisulam triggers apoptosis, halts mitosis, and normalizes blood vessels to combat cancer.</p>Fórmula:C11H5BrCl2NNaO3S2Cor e Forma:SolidPeso molecular:437.09Oxythiamine
CAS:<p>Oxythiamine (Hydroxythiamin) is a TK inhibitor that inhibits cancer cell proliferation, induces cell cycle arrest, and induces apoptosis.</p>Fórmula:C12H16N3O2SPureza:96.14% - 99.51%Cor e Forma:SolidPeso molecular:266.34MX106-4C
<p>MX106-4C is a survivin inhibitor that selectively targets ABCB1-positive colorectal cancer cells. It can work synergistically with Doxorubicin for enhanced anticancer effects or restore Doxorubicin sensitivity in drug-resistant ABCB1 cells.</p>Fórmula:C23H25BrN2O2Peso molecular:440.10994Flaccidoside II
CAS:<p>Flaccidoside II, an active triterpenoid saponin from Anemone flaccida rhizome, both inhibits proliferation and induces apoptosis in Malignant Peripheral Nerve</p>Fórmula:C59H96O25Pureza:98%Cor e Forma:SolidPeso molecular:1205.38Antitumor agent-96
<p>"Antitumor agent-96 (Compound D34) is a potent MRE11 inhibitor that down-regulates the homologous recombination (HR) pathway by binding to and suppressing the</p>Fórmula:C27H32N2O2Pureza:98%Cor e Forma:SolidPeso molecular:416.56Thalidomide-O-amido-PEG4-azide
CAS:<p>Thalidomide-O-amido-PEG4-azide is a polyethylene glycol (PEG) derivative serving as a linker for Proteolysis Targeting Chimeras (PROTACs) synthesis [1].</p>Fórmula:C25H32N6O10Pureza:98%Cor e Forma:SolidPeso molecular:576.56ZX782
<p>ZX782 acts as a GPX4 protein degrader and an inducer of ferroptosis (Ferroptosis), targeting GPX4 for destruction via both the ubiquitin-proteasome system and the autophagy-lysosome pathway. Following the degradation of GPX4 induced by ZX782, there is a significant increase in the accumulation of lipid reactive oxygen species (ROS) in HT1080 cells.</p>Fórmula:C39H48ClN5O8Cor e Forma:SolidPeso molecular:750.28TAT-GluN2BCTM
CAS:<p>TAT-GluN2BCTM is a membrane-permeable peptide that selectively targets active DAPK1 (Death-associated protein kinase 1) for lysosomal degradation, thereby</p>Fórmula:C224H374N86O54Pureza:98%Cor e Forma:SolidPeso molecular:5135.91Antitumor photosensitizer-4
<p>Antitumor Photosensitizer-4 (compound 10b), a conjugate of dasatinib and imatinib, serves as a potent tyrosine kinase inhibitor (TKI) targeting ABCG2.</p>Fórmula:C65H77ClN12O11SPureza:98%Cor e Forma:SolidPeso molecular:1269.9PROTAC GPX4 degrader-2
<p>PROTACGPX4 degrader-2 (compound 18a) is a proteolysis-targeting chimera (PROTAC) that targets the degradation of glutathione peroxidase 4 (GPX4), with a DC50, 48h value of 1.68 μM. It induces the accumulation of lipid peroxides and mitochondrial depolarization, subsequently triggering ferroptosis. Additionally, PROTACGPX4 degrader-2 exhibits antiproliferative activity.</p>Fórmula:C50H61ClN8O9Peso molecular:952.425Boc-AEVD-CHO
CAS:<p>Boc-AEVD-CHO, a selective Caspase 8 inhibitor, facilitates apoptosis research and the investigation of immune and inflammatory diseases [1] [2].</p>Fórmula:C22H36N4O10Pureza:98%Cor e Forma:SolidPeso molecular:516.54PROTAC-O4I2
CAS:<p>PROTAC-O4I2, a PROTAC ligand targeting splicing factor 3B1 (SF3B1), induced FLAG-SF3B1 degradation in K562 cells with an IC50 value of 0.244 μM.</p>Fórmula:C29H29ClN6O5SPureza:97.45%Cor e Forma:SolidPeso molecular:609.1Linsidomine
CAS:<p>Lincydomine relaxes smooth muscles, treats unstable angina, and opens human and guinea pig respiratory tracts.</p>Fórmula:C6H10N4O2Cor e Forma:Solid Off-WhitePeso molecular:170.17Thalidomide-NH-C8-NH2
CAS:<p>Thalidomide-NH-C8-NH2 is a synthetic E3 ligase ligand-linker for PROTAC, combining cereblon ligand and a specific linker.</p>Fórmula:C21H28N4O4Cor e Forma:SolidPeso molecular:400.479PI3K/AKT-IN-4
<p>PI3K/AKT-IN-4 (compound 3), a diterpenoid extracted from the roots and rhizomes of Salvia castanea Dielsf., exhibits antitumor properties by inhibiting cell viability and proliferation (IC 50 =4.72 μM) and promoting apoptosis in Hep3B cells. This compound obstructs the G0/G1 phase of the cell cycle, triggers mitochondrial dysfunction, and induces oxidative stress. Moreover, PI3K/AKT-IN-4 combats hepatocellular carcinoma through the inhibition of the PI3K-Akt signaling pathway and by interacting with PARP1 and CDK2 targets.</p>Fórmula:C19H26O2Cor e Forma:SolidPeso molecular:286.41OICR12694 TFA
CAS:<p>OICR12694 (JNJ-65234637) TFA, an orally active B cell lymphoma 6 (BCL6) inhibitor [1], demonstrates effectiveness in targeting BCL6 pathways.</p>Fórmula:C29H28ClF3N8O4·xC2HF3O2Cor e Forma:SolidGalloflavin Potassium
CAS:<p>Galloflavin Potassium is an inhibitor of lactate dehydrogenase.</p>Fórmula:C12H5KO8Cor e Forma:SolidPeso molecular:316.26Borrelidin
CAS:<p>Borrelidin (Treponemycin) is an inhibitor of trehalose-6-phosphate synthase, a nitrogen-containing macrolide antibiotic isolated from Streptomyces rochei.</p>Fórmula:C28H43NO6Pureza:98%Cor e Forma:White To Off-White PowderPeso molecular:489.64SBP-0636457
CAS:<p>SBP-0636457: SMAC mimetic, IAP inhibitor, binds BIR-domains (Ki=0.27μM), potential in tumor/cancer research.</p>Fórmula:C25H36N4O4Cor e Forma:SolidPeso molecular:456.587
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