Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5598 produtos de "Apoptose"
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dl-Maackiain
CAS:<p>1. dl-Maackiain (Demethylpterocarpin) induces apoptosis and growth suppression 2. MAK1 is the second functional gene cloned from Maackiain detoxification.</p>Fórmula:C16H12O5Pureza:97.36% - 99.89%Cor e Forma:SolidPeso molecular:284.26AT7519 Hydrochloride
CAS:<p>AT7519 Hydrochloride (AT7519 HCl) is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9.</p>Fórmula:C16H18Cl3N5O2Pureza:99.66% - 99.9%Cor e Forma:SolidPeso molecular:418.71G-749
CAS:<p>G-749, a new-type FLT3 inhibitor, exhibits effective and sustained inhibition of the FLT3 wild type and mutants.</p>Fórmula:C25H25BrN6O2Pureza:98.32% - 99.60%Cor e Forma:SolidPeso molecular:521.41Aurintricarboxylic acid
CAS:<p>Aurintricarboxylic acid (NSC-4056) blocks nucleases and topoisomerases, stopping nucleic acid binding.</p>Fórmula:C22H14O9Pureza:97.1%Cor e Forma:Deep Red Coarse Crystalline PowderPeso molecular:422.34PhiKan 083
CAS:<p>PhiKan 083 is a carbazole derivative</p>Fórmula:C16H18N2Pureza:98.37%Cor e Forma:SolidPeso molecular:238.33Hirsutine
CAS:<p>Hirsutine induces apoptosis and is a potent Dengue virus inhibitor exhibiting low cytotoxicity.Hirsutine has anticancer, cardioprotective, anti-hypertensive and</p>Fórmula:C22H28N2O3Pureza:99.36% - 99.98%Cor e Forma:SolidPeso molecular:368.47(Rac)-Antineoplaston A10
CAS:<p>Antineoplaston A10 is the first identified human antineoplaston, naturally occurring with anti-proliferative properties.</p>Fórmula:C13H14N2O3Pureza:98.41%Cor e Forma:SolidPeso molecular:246.26A-1210477
CAS:<p>A-1210477 is an effective and specific MCL-1 and Bcl-2 inhibitor (Ki/IC50: 0.454/26.2 nM).</p>Fórmula:C46H55N7O7SPureza:99.17% - 99.37%Cor e Forma:SolidPeso molecular:850.04Echinocystic acid
CAS:<p>EA, a natural triterpene, is found in herbs; it has anti-inflammatory and antioxidant properties.</p>Fórmula:C30H48O4Pureza:98% - 99.57%Cor e Forma:SolidPeso molecular:472.7Pseudolaric Acid B
CAS:<p>Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.</p>Fórmula:C23H28O8Pureza:98.91% - 99.84%Cor e Forma:SolidPeso molecular:432.46CCI-007
CAS:<p>CCI 007 is a selective inhibitor of MLL-r, CALM-AF10 and SET-NUP214 leukemia with IC50 of 3.5 uM against MLL-r leukemia cell line PER-485</p>Fórmula:C15H16N2O5SPureza:97.61%Cor e Forma:SolidPeso molecular:336.36Loganin
CAS:<p>Loganin inhibits Cox-1, suppresses TNF-α, and has antioxidant and anti-melanogenic properties.</p>Fórmula:C17H26O10Pureza:99.01% - >99.99%Cor e Forma:White PowderPeso molecular:390.38SHR0302
CAS:<p>SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3,</p>Fórmula:C18H22N8O2SPureza:99.11%Cor e Forma:SolidPeso molecular:414.48NVP-HSP990
CAS:<p>NVP-HSP990 (HSP990) is an effective and specific HSP90α/β inhibitor (IC50: 0.6 /0.8 nM).</p>Fórmula:C20H18FN5O2Pureza:98.03% - 99.32%Cor e Forma:SolidPeso molecular:379.39Ethyl 3,4-dihydroxybenzoate
CAS:<p>Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.</p>Fórmula:C9H10O4Pureza:99.88%Cor e Forma:White Crystal Or PowderPeso molecular:182.17Levistolide A
CAS:<p>1. Levistolide A (Diligustilide) inhibits liver fibrosis and angiogenesis.</p>Fórmula:C24H28O4Pureza:98.93% - 99.22%Cor e Forma:SolidPeso molecular:380.48Cabozantinib S-malate
CAS:<p>Cabozantinib S-malate (XL184) is the salt form of cabozantinib, an orally bioavailable, small molecule RTK inhibitor with potential antineoplastic activity.</p>Fórmula:C32H30FN3O10Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:635.59Liproxstatin-1
CAS:<p>Liproxstatin-1 is a potent and selective inhibitor of iron death (IC50=22 nM).</p>Fórmula:C19H21ClN4Pureza:97.11% - 99.44%Cor e Forma:SolidPeso molecular:340.85SZL P1-41
CAS:<p>SZL P1-41 inhibits Skp2, blocks complex formation, and halts ubiquitination, promoting cell senescence, reducing glycolysis, and exhibiting antitumor effects.</p>Fórmula:C24H24N2O3SPureza:99.60% - 99.87%Cor e Forma:SolidPeso molecular:420.52MK-8745
CAS:<p>MK-8745 is a potent and selective Aurora A inhibitor.</p>Fórmula:C20H19ClFN5OSPureza:99.09% - 99.79%Cor e Forma:SolidPeso molecular:431.91Panobinostat
CAS:<p>Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity.</p>Fórmula:C21H23N3O2Pureza:97.2% - 99.81%Cor e Forma:Yellow SolidPeso molecular:349.43Scopoletin
CAS:<p>Scopoletin (Esculetin 6-methyl ether) is a plant growth factor derived from the root of Scopolia carniolica, inhibits of acetylcholinesterase (AChE).</p>Fórmula:C10H8O4Pureza:97.06% - 99.88%Cor e Forma:Yellow To Beige Crystalline PowderPeso molecular:192.17Cucurbitacin B
CAS:<p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>Fórmula:C32H46O8Pureza:97.1% - 99.33%Cor e Forma:SolidPeso molecular:558.7Kinsenoside
CAS:<p>Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities.</p>Fórmula:C10H16O8Pureza:99.2% - >99.99%Cor e Forma:SolidPeso molecular:264.235-Geranoxy-7-methoxycoumarin
CAS:<p>5-Geranoxy-7-methoxycoumarin shows antifungal activity.</p>Fórmula:C20H24O4Pureza:98.94% - 99.99%Cor e Forma:SolidPeso molecular:328.4INH1
CAS:<p>INH1 (IBT13131) is a cell-permeable Hec1 inhibitor that specifically disrupts the Hec1/Nek2 interaction.</p>Fórmula:C18H16N2OSPureza:99.80%Cor e Forma:SolidPeso molecular:308.4FX1
CAS:<p>FX1 is an effective and selective BCL6 inhibitor (IC50: 35 μM).</p>Fórmula:C14H9ClN2O4S2Pureza:97.59%Cor e Forma:SolidPeso molecular:368.82ZM-447439
CAS:<p>ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.</p>Fórmula:C29H31N5O4Pureza:99.11% - 99.59%Cor e Forma:Pale Yellow SolidPeso molecular:513.59Rottlerin
CAS:<p>Rottlerin (NSC-56346), a Mallotus Philippinensis extract, inhibits PKC (3-100 μM IC50); triggers apoptosis by activating caspase 3.</p>Fórmula:C30H28O8Pureza:97.41% - 99.44%Cor e Forma:Orange To Brown PowderPeso molecular:516.54SP600125
CAS:<p>SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive</p>Fórmula:C14H8N2OPureza:97.63% - 99.82%Cor e Forma:SolidPeso molecular:220.23ASK1-IN-2
CAS:<p>ASK1-IN-2: oral ASK1 inhibitor, IC50 32.8 nM, potential ulcerative colitis treatment.</p>Fórmula:C19H17FN6OPureza:98.79%Cor e Forma:SolidPeso molecular:364.38GSK-923295
CAS:<p>GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).</p>Fórmula:C32H38ClN5O4Pureza:96.22% - 98.02%Cor e Forma:SolidPeso molecular:592.13Mimosine
CAS:<p>L-Mimosine (Leucenol) is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca and acts as an iron chelator.</p>Fórmula:C8H10N2O4Pureza:99.2% - 99.84%Cor e Forma:Crystals From Water SolidPeso molecular:198.18PHA-767491 hydrochloride
CAS:<p>PHA-767491 (CAY-10572) is a potent Cdc7/CDK9 inhibitor (IC50: 10/34 nM), selective against GSK3-β, CDK1/2, CDK5, MK2, CHK2, PLK1.</p>Fórmula:C12H12ClN3OPureza:99.56% - 99.92%Cor e Forma:SolidPeso molecular:249.69KY-05009
CAS:<p>KY-05009 blocks TGF-β1 EMT in lung cancer cells, inhibits TNIK, Wnt genes, induces apoptosis, and is an ATP-competitive TNIK inhibitor (Ki = 100 nM).</p>Fórmula:C18H16N4O2SPureza:99.89%Cor e Forma:SolidPeso molecular:352.411A-116
CAS:<p>1A-116 is a specific Rac1 inhibitor.</p>Fórmula:C16H16F3N3Pureza:99.71%Cor e Forma:SolidPeso molecular:307.31Urolithin A
CAS:<p>Urolithin A is a metabolite of ellagic acid, which inhibits DNA synthesis and induces apoptosis and autophagy. Cost-effective and quality-assured.</p>Fórmula:C13H8O4Pureza:99.14% - 99.67%Cor e Forma:SolidPeso molecular:228.2TJ191
CAS:<p>TJ191 is a selective anti-cancer agent, targeting low TβRIII-expressing malignant T-cell leukemia/lymphoma cells.</p>Fórmula:C13H21NO2SPureza:99.28%Cor e Forma:SolidPeso molecular:255.38α-Thujone
CAS:<p>α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.</p>Fórmula:C10H16OPureza:97.02% - 98.41%Cor e Forma:Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Peso molecular:152.23ASP3026
CAS:<p>ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies,and Positive for Anaplastic Lymphoma Kinase.</p>Fórmula:C29H40N8O3SPureza:98.78% - 99.81%Cor e Forma:SolidPeso molecular:580.74CCT 137690
CAS:<p>CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).</p>Fórmula:C26H31BrN8OPureza:98.51% - 99.89%Cor e Forma:SolidPeso molecular:551.48BTZO-1
CAS:<p>BTZO-1 is an antioxidant response element (ARE) activator with cardioprotective activity.</p>Fórmula:C13H8N2OSPureza:99.46%Cor e Forma:SolidPeso molecular:240.28CI-1040
CAS:<p>CI-1040 (PD 184352) (PD184352) is an ATP non-competitive MEK1/2 inhibitor (IC50: 17 nM).</p>Fórmula:C17H14ClF2IN2O2Pureza:99.64%Cor e Forma:Off-White To Pale Beige SolidPeso molecular:478.66C-DIM12
CAS:<p>C-DIM12 boosts Nurr1 gene expression, heightens Nurr1 protein in neurons, and improves survival against 6-OHDA.</p>Fórmula:C23H17ClN2Pureza:97.72% - ≥95%Cor e Forma:SolidPeso molecular:356.85SJ-172550
CAS:<p>SJ-172550 is a small molecule inhibitor of MDMX (EC50: 5 μM).</p>Fórmula:C22H21ClN2O5Pureza:99.87%Cor e Forma:SolidPeso molecular:428.87Momelotinib
CAS:<p>Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.</p>Fórmula:C23H22N6O2Pureza:97.47% - 99.56%Cor e Forma:SolidPeso molecular:414.46Kahweol
CAS:<p>Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaB</p>Fórmula:C20H26O3Pureza:99.26% - 99.86%Cor e Forma:Off-White To Yellow SolidPeso molecular:314.42TC11
CAS:<p>TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis</p>Fórmula:C20H22N2O2Pureza:97.86%Cor e Forma:SolidPeso molecular:322.4Oleic acid
CAS:<p>Oleic acid, a common unsaturated fat, is used in oleates, lotions, and as a pharma solvent.</p>Fórmula:C18H34O2Pureza:97.14% - 99.91%Cor e Forma:Colorless Or Nearly Colorless Liq (Above 5-7 Deg C) Oleic Acid Is A Colorless To Pale Yellow Liquid With A Mild Odor Floats On Water (Uscg 1999)Peso molecular:282.46RA-9
CAS:<p>RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs), with favorable toxicity profile and anticancer activity.</p>Fórmula:C19H15N3O5Pureza:98.15%Cor e Forma:SolidPeso molecular:365.34
