Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(939 produtos)
- ACK(1 produtos)
- AChR(575 produtos)
- ATP Citrato Liase(16 produtos)
- Receptor adrenérgico(2.945 produtos)
- BACE(36 produtos)
- Beta Amilóide(205 produtos)
- CaMK(69 produtos)
- COX(561 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor GABA(336 produtos)
- Gama-secretase(59 produtos)
- GluR(255 produtos)
- GlyT(24 produtos)
- Receptor de Histamina(358 produtos)
- LRRK2(33 produtos)
- Receptor de Melatonina(24 produtos)
- NMDAR(28 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(297 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5400 produtos de "Neurociência"
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AChE-IN-39
<p>AChE-IN-39 (Compound 7c), with an IC50 value of 0.058 μM, is an acetylcholinesterase (AChE) inhibitor known for its DPPH scavenging activity and potential to</p>Fórmula:C19H15NO3Cor e Forma:SolidPeso molecular:305.33pCPA methyl ester hydrochloride
CAS:<p>pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.</p>Fórmula:C10H13Cl2NO2Pureza:99.73% - 99.88%Cor e Forma:SolidPeso molecular:250.12AChE-IN-46
<p>AChE-IN-46 (compound 4), a β-cyclocostunolide, functions as an acetylcholinesterase (AChE) inhibitor [1].</p>Fórmula:C15H22O2Cor e Forma:SolidPeso molecular:234.33(Gln22)-Amyloid β-Protein (1-42)
CAS:<p>(Gln22)-Amyloid β-Protein (1-42), a Dutch mutation (E22Q) variant of β-Amyloid (1-42), demonstrates increased fibrillogenic and pathogenic characteristics [1].</p>Fórmula:C203H312N56O59SCor e Forma:SolidPeso molecular:4513.05Orexin B, rat, mouse TFA
<p>Orexin B, rat/mouse TFA, activates OX1-R & OX2-R receptors, influencing food intake, energy, and sleep regulation.</p>Fórmula:C128H216F3N45O36SCor e Forma:SolidPeso molecular:3050.42Acetyl-Tau Peptide (273-284) amide
CAS:<p>Acetyl-Tau Peptide (273-284) amide inhibits Ac-Aβ(25–35)-NH2 aggregation and models Aβ/Tau interaction.</p>Fórmula:C64H116N18O17Cor e Forma:SolidPeso molecular:1409.72(Glu20)-Amyloid β-Protein (1-42)
CAS:<p>(Glu20)-Amyloid β-Protein (1-42) represents a variant of amyloid β-protein (Aβ) that fibrillizes more slowly.</p>Fórmula:C199H309N55O62SCor e Forma:SolidPeso molecular:4495.98Litoxetine HCl
<p>Litoxetine HCl, an SSRI and 5-HT antagonist, treats urinary incontinence and relaxes rat oesophageal muscles without antimuscarinic effects.</p>Fórmula:C16H20ClNOPureza:99.56% - 99.75%Cor e Forma:SoildPeso molecular:277.79CPN-267 TFA
<p>CPN-267 (compound 7b) TFA is a selective agonist of neuromedin U receptor 1 (NMUR1) with an EC50 of 0.25 nM. This compound inhibits weight gain in mice and is applicable in obesity research.</p>Fórmula:C54H68F6N16O12SCor e Forma:SolidPeso molecular:1279.27(D-Asp1)-Amyloid β-Protein (1-42)
CAS:<p>(D-Asp1)-Amyloid β-Protein (1-42), a peptide fragment of amyloid β-protein (Aβ), serves as the primary constituent of vascular and parenchymal amyloid deposits</p>Fórmula:C203H311N55O60SCor e Forma:SolidPeso molecular:4514.04KRP-199 sodium
<p>KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.</p>Fórmula:C22H12F3N5Na2O7Pureza:97.27%Cor e Forma:SoildPeso molecular:561.33mGluR3 modulator-1
CAS:<p>1-ethyl-3-morpholin-4-yl tetrahydroisoquinoline: mGluR3 modulator, potential for Parkinson's.</p>Fórmula:C16H21N3OPureza:98.99%Cor e Forma:SolidPeso molecular:271.36Lisuride maleate
CAS:<p>Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.</p>Fórmula:C24H30N4O5Pureza:99.85%Cor e Forma:SolidPeso molecular:454.52BSB
CAS:<p>BSB is a Congo red-derived fluorescent probe, an amyloid protein imaging agent, interacting with amyloid fibrils formed by Aβ (1-40) peptides in rodents.</p>Fórmula:C24H17BrO6Pureza:95.53%Cor e Forma:SolidPeso molecular:481.29Salvianolic acid H
CAS:<p>Salvianolic acid H is a strong inhibitor of acetylcholinesterase (AChE) [1].</p>Fórmula:C27H22O12Cor e Forma:SolidPeso molecular:538.46Amyloid β Peptide (42-1)(human) acetate
<p>Amyloid β Peptide (42-1)(human) acetate is the inactive form of Amyloid β Peptide (1-42).</p>Pureza:95.20%Cor e Forma:SoildMR33317
<p>MR33317 is an inhibitor of acetylcholinesterase with an IC50 value of 41 nM. Additionally, it acts as an agonist for brain 5-HT4 receptors.</p>Fórmula:C22H28ClN3O2Peso molecular:401.187Amyloid β-Protein (1-24)
CAS:<p>Amyloid β-Protein (1-24) is a peptide identified through peptide screening. This tool predominantly employs immunoassays to gather and analyze active peptides. Peptide screening is utilized in studies involving protein interactions, functional analysis, and epitope screening, particularly relevant in the research and development of active molecules.</p>Fórmula:C130H183N35O40Peso molecular:2876.05R 50595
CAS:<p>R 50595 is a selective non-competitive cisapride antagonist.</p>Fórmula:C30H35Cl2F2N3O3Pureza:98%Cor e Forma:SolidPeso molecular:594.52Malaoxon
CAS:<p>Malaoxon is used as an insecticide.</p>Fórmula:C10H19O7PSCor e Forma:SolidPeso molecular:314.29NNC 11-1607
CAS:<p>NNC 11-1607 is a functionally selective agonist of M(1)/M(4) mAChR.</p>Fórmula:C30H32N6O2S2Cor e Forma:SolidPeso molecular:572.74N-Desmethyl Pimavanserin
CAS:<p>N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.</p>Fórmula:C24H32FN3O2Pureza:98.02%Cor e Forma:SolidPeso molecular:413.53Endosulfan I
CAS:<p>Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complex</p>Fórmula:C9H6Cl6O3SPureza:99.86%Cor e Forma:SolidPeso molecular:406.93Kynuramine
CAS:<p>Kynuramine is an aromatic ketone containing the aniline structure.</p>Fórmula:C9H12N2OCor e Forma:SolidPeso molecular:164.20Biphenyl-3′,3,4,4′-tetrol
CAS:<p>Biphenyl-3′,3,4,4′-tetrol (BPT) is a potent inhibitor of Aβ40 aggregation and can be utilized in research related to neurodegenerative diseases such as Alzheimer's.</p>Fórmula:C12H10O4Cor e Forma:SolidPeso molecular:218.21STX-107
CAS:<p>STX-107 is a potent and selective mGluR5 agonist for the study of Fragile X Syndrome.</p>Fórmula:C18H10FN3SPureza:99.17%Cor e Forma:SolidPeso molecular:319.365-methoxy-α-Ethyltryptamine
CAS:<p>5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects. </p>Fórmula:C13H18N2OPureza:98.25%Cor e Forma:SolidPeso molecular:218.29Antidepressant agent 5
CAS:<p>Antidepressant agent 5 is a 7-substituted tetrahydroisoquinoline derivative with antidepressant activity.Antidepressant agent 5 acts similarly to magnoflorine</p>Fórmula:C20H25NO3Pureza:99.34%Cor e Forma:SoildPeso molecular:327.42Suntinorexton
CAS:<p>Suntinorexton (TAK 861) is an orexin type 2 receptor (OX2R) agonist used in the study of neurologic disorders.</p>Fórmula:C23H28F2N2O4SPureza:99.89%Cor e Forma:SolidPeso molecular:466.54P-gb-IN-1
CAS:<p>P-gb-IN-1 is a potent P-glycoprotein (P-gp) inhibitor that exhibits reverse activity by inhibiting P-gp outflow.</p>Fórmula:C30H28N2O6Pureza:99.58%Cor e Forma:SoildPeso molecular:512.55CDD0102 HCl
CAS:<p>CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.</p>Fórmula:C8H13ClN4OPureza:99.7%Cor e Forma:SoildPeso molecular:216.67Nemifitide diTFA
CAS:<p>Nemifitide diTFA is a synthetic pentapeptide with antidepressant properties, resembling MIF, that crosses the blood-brain barrier.</p>Fórmula:C37H45F7N10O10Pureza:99.78% - 99.84%Cor e Forma:SolidPeso molecular:922.85-HT6R antagonist 6
<p>5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.</p>Fórmula:C24H26N4O2SCor e Forma:SolidPeso molecular:434.55GABAA receptor modulator-4
<p>GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.</p>Fórmula:C15H17BrO4SCor e Forma:SolidPeso molecular:373.26Brexpiprazole S-oxide
CAS:<p>Brexpiprazole S-oxide is the main metabolite of Brexpiprazole, a human 5-HT1A and dopamine receptor partial agonist (Ki: 0.12, 0.3 nM).</p>Fórmula:C25H27N3O3SPureza:98%Cor e Forma:SolidPeso molecular:449.57Aβ-IN-8
<p>Aβ-IN-8, also known as compound 7e, is a potent inhibitor of Aβ aggregation [1].</p>Fórmula:C22H16F3N3O3SCor e Forma:SolidPeso molecular:459.44hAChE-IN-4
<p>Compd 5d (hAChE-IN-4) is a potent hAChE inhibitor that readily crosses the blood-brain barrier, exhibiting an IC50 of 0.25 μM, and is utilized in the study of</p>Fórmula:C30H23Cl3N2O3Cor e Forma:SolidPeso molecular:565.87AZD4694 Precursor
CAS:<p>AZD4694 Precursor used for synthesizing [18F]AZD4694, a high-affinity amyloid-β imaging agent.</p>Fórmula:C22H25N3O7Cor e Forma:SolidPeso molecular:443.45(S)-AMPA HCl
<p>(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.</p>Fórmula:C7H11ClN2O4Pureza:99.18%Cor e Forma:SolidPeso molecular:222.63Syntide 2 TFA
Syntide 2 (TFA) is a CaMKII substrate that selectively hinders GA response without affecting other plant processes.Fórmula:C70H123N20F3O20Cor e Forma:SolidPeso molecular:1621.84OXA(17-33) TFA
<p>OXA(17-33) TFA: Potent OX1 agonist, ~23x more selective for OX1 (EC50=8.29nM) than OX2 (187nM).</p>Fórmula:C81H126F3N23O24Cor e Forma:SolidPeso molecular:1863Anti-Amyloid β Antibody (scFv59)
<p>Anti-Amyloid Beta Antibody (scFv59) is a human-derived antibody produced in CHO cells that targets Amyloid-β. For isotype control, please refer to Human IgG1 kappa, Isotype Control.</p>Cor e Forma:Odour LiquidOM99-2 TFA
CAS:<p>OM99-2 TFA, an 8-residue inhibitor of brain memapsin 2, has a Ki of 9.58 nM, showing promise in Alzheimer's research.</p>Fórmula:C43H65F3N8O16Cor e Forma:SolidPeso molecular:1007.028BuChE-IN-13
<p>BuChE-IN-13 (compound 3) is a BuChE inhibitor that exhibits anti-Alzheimers activity. It is utilized in the research of neurodegenerative diseases.</p>Cor e Forma:Odour SolidmcK6A1
<p>mcK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.</p>Fórmula:C71H99N17O16Cor e Forma:SolidPeso molecular:1446.65Biotin-β-Amyloid (1-42), human TFA
<p>Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in the</p>Fórmula:C215H326F3N57O64S2Cor e Forma:SolidPeso molecular:4854.36AChE/Aβ-IN-6
<p>BACE1-IN-15 (compound 4j) serves as an effective inhibitor of BACE1 (β-secretase), efficiently mitigating the copper-induced toxicity of Aβ, with an EC50 value of 0.68 μM.</p>Cor e Forma:Odour SolidFITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)
<p>FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium) is a FITC-labeled amyloid beta monomer, Alzheimer’s research, drug screening, and biomolecular studies.</p>Fórmula:C227H330N58O66S2Cor e Forma:SolidPeso molecular:4991.53G923-0271
CAS:<p>G923-0271 is a TDP-43 inhibitor that improves disease phenotypes in TDP-43 nematode models and reduces the overexpression of human TDP-43, ALS FTD.</p>Fórmula:C28H23FN4OCor e Forma:SolidPeso molecular:450.51BTMPS
CAS:<p>BTMPS is a usage-dependent nicotinic antagonist capable of reducing acute withdrawal symptoms associated with morphine use.</p>Fórmula:C28H52N2O4Pureza:98.1%Cor e Forma:SolidPeso molecular:480.72Dapoxetine
CAS:<p>Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.</p>Fórmula:C21H23NOPureza:99.73%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:305.42GABA-A Receptor Ligand-1
<p>GABA-A Receptor Ligand-1 (Compound 4) is a ligand for the GABA-A receptor with a pKi of 7.27. It alleviates mitochondrial dysfunction, promotes neurite outgrowth and neuronal regeneration, and demonstrates neuroprotective effects in a rat ischemic stroke model.</p>Fórmula:C20H20FN3OCor e Forma:SolidPeso molecular:337.391Xenopus orexin B
CAS:Xenopus orexin B, a neuropeptide identified as an endogenous ligand for an orphan G-protein-coupled receptor, acts as a potent agonist of OX2R [1].Fórmula:C130H219N45O40S2Cor e Forma:SolidPeso molecular:3116.54Amyloid-Forming peptide GNNQQNY
CAS:<p>Amyloid-Forming peptide GNNQQNY, a biologically active heptapeptide derived from the N-terminal prion-determining domain of yeast Sup35, is instrumental in</p>Fórmula:C33H48N12O14Cor e Forma:SolidPeso molecular:836.81Dalidnetug
CAS:<p>Dalidnetug is a humanized monoclonal antibody that targets human β-amyloid precursor protein (APP). By specifically binding to APP, Dalidnetug reduces the production of β-amyloid (Aβ), thereby demonstrating activity in clearing β-amyloid. This compound holds potential for research in Alzheimer's disease.</p>Cor e Forma:LiquidAChE-IN-70
<p>AChE-IN-70 (compound 4) is an acetylcholinesterase inhibitor. It exhibits larvicidal activity against mosquito larvae (Culex pipiens L.), making it useful for mosquito control research.</p>Cor e Forma:Odour SolidhAChE/hBuChE/GSK-3β-IN-1
<p>hAChE/hBuChE/GSK-3β-IN-1 (Compound 6c) is a multi-target compound designed for Alzheimer's treatment capable of crossing the blood-brain barrier. It inhibits hAChE with an IC50 of 28.88 nM, hBuChE with an IC50 of 131.90 nM, and GSK-3β with an IC50 of 51.42 nM. Additionally, it acts as an inhibitor of tau protein and Aβ protein aggregation.</p>Fórmula:C19H15NO4Cor e Forma:SolidPeso molecular:321.327Pomaglumetad methionil anhydrous
CAS:<p>LY2140023, potential schizophrenia treatment, is an oral prodrug of LY404039, a selective mGlu2/3 agonist.</p>Fórmula:C12H18N2O7S2Pureza:98%Cor e Forma:SolidPeso molecular:366.41GluN2B receptor modulator-1
CAS:<p>GluN2B receptor modulator-1 is a selective negative allosteric modulator of NMDA receptor GluN2B subunits (IC50 31 nM), valuable for neuropharmacology studies.</p>Fórmula:C17H15F3N4O2SPureza:99.56%Cor e Forma:SolidPeso molecular:396.39Lu AE51090
CAS:<p>Lu AE51090 is a selective muscarinic M1 receptor agonist with minimal off-target effects, receptor function and selective pharmacological modulation.</p>Fórmula:C24H29N3O3Pureza:99.57%Cor e Forma:SolidPeso molecular:407.51SB 216641
CAS:<p>SB 216641 is a 5-HT (1B/1D) antagonist with anxiolytic activity for the study of anxiety disorders and depression.</p>Fórmula:C28H30N4O4Pureza:98.09%Cor e Forma:SolidPeso molecular:486.56TIM-098a
<p>TIM-098a is a selective AAK1 inhibitor with an IC50 of 0.24 µM. It does not inhibit CaMKK isoforms. By inhibiting AAK1 kinase activity, TIM-098a disrupts AAK1-regulated endocytosis.</p>Fórmula:C18H11N3O2Peso molecular:301.08513FITC-β-Ala-Amyloid β-Protein (1-42)
CAS:<p>FITC-β-Ala-Amyloid β-Protein (1-42) is a polypeptide identified through peptide screening. This screening method predominantly utilizes immunoassays to gather active polypeptides and is used in studying protein interactions, conducting functional analyses, and screening antigen epitopes, with particular application in the research and development of active molecules.</p>Fórmula:C227H327N57O66S2Peso molecular:4971.34251GABAA receptor modulator-3
<p>GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.</p>Fórmula:C18H22O2Cor e Forma:SolidPeso molecular:270.37Otaplimastat HCl
CAS:<p>Otaplimastat HCl is an MMP inhibitor reducing NMDA-mediated excitotoxicity and oxidative stress, restoring TIMP levels, and protecting vascular permeability.</p>Fórmula:C28H35ClN6O5Pureza:100%Peso molecular:571.07AChE/MAO-B-IN-7
<p>AChE/MAO-B-IN-7 (VAV-8) is a compound that acts as a dual inhibitor of acetylcholinesterase (AChE) and MAO-B, with the ability to cross the blood-brain barrier. It also inhibits the aggregation of Aβ42, making it a valuable compound for Alzheimer's disease (AD) research.</p>Fórmula:C22H21N3O3Cor e Forma:SolidPeso molecular:375.42YS-370
CAS:<p>YS-370 orally blocks P-gp, moderately inhibits CYP3A4, reverses drug resistance, and enhances paclitaxel's anticancer effects.</p>Fórmula:C37H35BrN4O3Pureza:98.055%Cor e Forma:SolidPeso molecular:663.6LEK 8804
CAS:<p>LEK 8804 is a 5-HT(2) receptor antagonist and 5-HT(1A) receptor agonist.</p>Fórmula:C19H19N3OCor e Forma:SolidPeso molecular:305.375-HT5AR/5-HT6R ligand-1
<p>5-HT5AR/5-HT6R ligand-1 (Compound PP10) is a ligand for serotonin receptors, exhibiting high affinity for the 5-HT5A and 5-HT6 receptors with Ki values of 59 nM and 96 nM, respectively. It possesses some antiproliferative activity against tumor cells and can be utilized in cancer research.</p>Fórmula:C25H30N4O2SCor e Forma:SolidPeso molecular:450.6I2-IRs ligand-1
<p>I2-IRs ligand-1 (Compound 12d) is an orally active compound capable of crossing the blood-brain barrier. It exhibits high affinity for imidazoline I2 receptors (I2-IRs) with a pKi of 9.98. This compound can enhance cognitive deficits in aging mice and possesses analgesic, anti-inflammatory, and neuroprotective properties. I2-IRs ligand-1 is applicable for research in Alzheimer's disease and related pain disorders.</p>Fórmula:C21H23ClFN2O4PCor e Forma:SolidPeso molecular:452.84Polyglutamine binding peptide 1
CAS:<p>Polyglutamine binding peptide 1 (QBP1) is a peptide inhibitor of polyglutamine (polyQ). It effectively inhibits polyQ protein aggregation in vitro and prevents polyQ-induced cell death in cell cultures.</p>Fórmula:C72H90N16O16Cor e Forma:SolidPeso molecular:1435.58(Iso)-Landipirdine
CAS:<p>(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.</p>Fórmula:C18H19FN2O3SPureza:98.50%Cor e Forma:SoildPeso molecular:362.42Flupyradifurone
CAS:<p>Flupyradifurone (flupyradifurone) is a systemic insecticide and nicotinic acetylcholine receptor (nAChR) agonist interfer nervous system of insects.</p>Fórmula:C12H11ClF2N2O2Pureza:99.83%Cor e Forma:SolidPeso molecular:288.68Crenezumab
CAS:<p>Crenezumab (MABT 5102A) is a fully humanized anti-amyloid-beta antibody that binds to multiple forms of amyloid-beta (Aβ) for the study of Alzheimer's disease.</p>Pureza:97.5% (SDS-PAGE); 95.3% (SEC-HPLC) - 97.5% (SDS-PAGE); 95.3% (SEC-HPLC)Cor e Forma:Liquidisomer-Cilansetron
CAS:<p>isomer-Cilansetron is an isomer of Cilansetron.</p>Fórmula:C20H21N3OPureza:99.92% - 99.96%Cor e Forma:SoildPeso molecular:319.4Xylamidine
CAS:<p>Xylamidine is a biochemical.</p>Fórmula:C19H24N2O2Cor e Forma:SolidPeso molecular:312.41(Iso)-Atagabalin HCl
CAS:<p>(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.</p>Fórmula:C10H20ClNO2Pureza:99.26% - >99.99%Cor e Forma:SoildPeso molecular:221.72FGIN-1-43
CAS:<p>FGIN-1-43 is a potent and specific ligand for the mitochondrial DBI receptor.</p>Fórmula:C28H36Cl2N2OPureza:99.57%Cor e Forma:SolidPeso molecular:487.5(+)-Coclaurine hydrochloride
CAS:<p>(+)-Coclaurine hydrochloride, also known as (+)-(R)-Coclaurine, is a benzyltetrahydroisoquinoline alkaloid extracted from multiple plant species.</p>Fórmula:C17H20ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:321.8Proadrenomedullin (1-20), human
CAS:<p>Endogenous peptide; agonist of MRGPRX2 (EC50=251 nM); noncompetitive inhibitor of nicotinic receptors; reduces catecholamine secretion; antihypertensive.</p>Fórmula:C112H178N36O27Pureza:98%Cor e Forma:SolidPeso molecular:2460.84Mirtazapine N-oxide
CAS:<p>Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.</p>Fórmula:C17H19N3OCor e Forma:SolidPeso molecular:281.3592002-H20
CAS:<p>2002-H20 is an Aβ42-induced cytotoxicity inhibitor. It acts by binding the Alzheimer's Aβ peptide and reducing its cytotoxicity.</p>Fórmula:C20H15N3O3Pureza:98%Cor e Forma:SolidPeso molecular:345.358Fentonium bromide
CAS:<p>Fentonium bromide is a biochemical.</p>Fórmula:C31H34BrNO4Cor e Forma:SolidPeso molecular:564.51Ebiratide TFA
<p>Ebiratide (HOE-427) TFA is a derivative of ACTH4-9 that exerts its effect directly on the central nervous system, enhancing memory. Ebiratide TFA also promotes the metabolism of acetylcholine (ACh) in the rat brain.</p>Fórmula:C48H73N11O10S·xC2HF3O2Cor e Forma:SolidPeso molecular:996.23 (free base)BSBM6
CAS:<p>BSBM6 is an inhibitor of Aβ aggregation and neuronal toxicity that acts by reversing the aggregation and toxicity of amyloid-β peptides.</p>Fórmula:C23H29N3O5Pureza:98%Cor e Forma:SolidPeso molecular:427.49Desmethyl Mirtazapine (hydrochloride)
CAS:<p>Desmethyl mirtazapine is a metabolite of the antidepressant mirtazapine.1It is formed from mirtazapine by the cytochrome P450 (CYP) isoform CYP3A4.</p>Fórmula:C16H18ClN3Cor e Forma:SolidPeso molecular:287.79Emamectin B1a
CAS:<p>Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.</p>Fórmula:C49H75NO13Cor e Forma:SolidPeso molecular:886.133Alverine hydrochloride
CAS:<p>Alverine hydrochloride is a parasympatholytic.</p>Fórmula:C20H28ClNCor e Forma:SolidPeso molecular:317.9(±)-LY367385
CAS:<p>(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.</p>Fórmula:C10H11NO4Cor e Forma:SolidPeso molecular:209.201Org 13011
CAS:<p>Org 13011 has CNS activity and induces conditioned taste aversion by mediating 5-HT 1A receptors.</p>Fórmula:C18H25F3N4OPureza:98.02%Cor e Forma:SoildPeso molecular:370.41GSK-3β inhibitor 27
<p>GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.</p>Fórmula:C16H17ClN4O2Cor e Forma:SolidPeso molecular:332.79Binospirone
CAS:<p>Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of movement disorders associated with neurologic dysfunction.</p>Fórmula:C20H26N2O4Pureza:97.57% - 98.96%Cor e Forma:SoildPeso molecular:358.435-MeO-pyr-T
CAS:<p>5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.</p>Fórmula:C15H20N2OCor e Forma:SolidPeso molecular:244.33ALEPH hydrochloride
CAS:<p>ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.</p>Fórmula:C12H20ClNO2SCor e Forma:SolidPeso molecular:277.81ECPLA
CAS:<p>ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.</p>Fórmula:C21H25N3OCor e Forma:SolidPeso molecular:335.44Ethylpropyltryptamine
CAS:<p>Ethylpropyltryptamine (EPT) is an orally active novel psychoactive substance. It is predicted to act as a partial agonist of the 5-HT2A receptor.</p>Fórmula:C15H22N2Cor e Forma:SolidPeso molecular:230.354-Hydroxy MET
CAS:<p>4-Hydroxy MET (4-HO-MET) is a tryptamine-based new psychoactive substance (NPS), structurally similar to the endogenous neurotransmitter serotonin. It has hallucinogenic properties that affect mood, movement, and cognitive functions.</p>Fórmula:C13H18N2OCor e Forma:SolidPeso molecular:218.34-Chloromethamphetamine hydrochloride
CAS:<p>4-Chloromethamphetamine hydrochloride is a novel psychoactive substance belonging to the amphetamine class.</p>Fórmula:C10H15Cl2NCor e Forma:SolidPeso molecular:220.144-fluoro MBZP
CAS:<p>4-fluoro MBZP is a novel psychoactive substance in the phenylpiperazine class, utilized for studies on the 5-HT2 receptors in the central nervous system.</p>Fórmula:C12H17FN2Cor e Forma:SolidPeso molecular:208.285-HT2C agonist-4
CAS:<p>Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.</p>Fórmula:C24H25N5OCor e Forma:SolidPeso molecular:399.49
