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Neurociência

Neurociência

Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.

Subcategorias de "Neurociência"

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Foram encontrados 5398 produtos de "Neurociência"

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  • β-Amyloid (22-35)

    CAS:
    <p>β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells.</p>
    Fórmula:C59H102N16O21S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1403.62
  • (Rac)-Norcisapride

    CAS:
    <p>Norcisapride, a 5-HT3 and 5-HT4 agonist, treats GI, orofacial, and ENT disorders.</p>
    Fórmula:C14H20ClN3O3
    Pureza:99.32%
    Cor e Forma:Soild
    Peso molecular:313.78
  • MIDD0301

    CAS:
    <p>MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.</p>
    Fórmula:C19H13BrFN3O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:414.23
  • Anticonvulsant agent 9


    <p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>
    Fórmula:C22H24N4O2
    Cor e Forma:Solid
    Peso molecular:376.45
  • β-Amyloid (35-42)

    CAS:
    <p>β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.</p>
    Fórmula:C33H60N8O9S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:744.94
  • Lanuginosine

    CAS:
    <p>Lanuginosine, an aporphine alkaloid, exhibits cytotoxicity against U251.</p>
    Fórmula:C18H11NO4
    Cor e Forma:Solid
    Peso molecular:305.28
  • CaMKIIα-PHOTAC


    <p>CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα).</p>
    Fórmula:C54H58Cl2N10O11
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1094
  • NMDA receptor antagonist 8


    <p>Compound (R)-10a, an NMDA receptor antagonist, exhibits selectivity for the GluN2B subunit, possessing a Ki of 265 nM and an IC50 of 62 nM.</p>
    Fórmula:C22H27N3O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:349.47
  • 5-HT6R antagonist 1


    <p>Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stability</p>
    Fórmula:C17H22F2N6O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:364.39
  • Nardoguaianone J

    CAS:
    <p>Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].</p>
    Fórmula:C15H22O2
    Cor e Forma:Solid
    Peso molecular:234.33
  • CUR-IPA


    <p>CUR-IPA is a cholinesterase inhibitor with IC50 values of 5.99 μM for eAChE (electric eel), 59.30 μM for hAChE (human), and 60.66 μM for hBChE (human). It has free radical scavenging and antioxidant activity and is useful for researching cognitive dysfunction.</p>
    Fórmula:C43H38N2O8
    Cor e Forma:Solid
    Peso molecular:710.77
  • AChE/BuChE/MAO-B-IN-2


    <p>AChE/BuChE/MAO-B-IN-2 (compound 4b) is a potent inhibitor of AChE, BuChE, and hu MAO-B, with respective IC50 values of 5.3 μM, 12.4 μM, and 1.9±0.08 μM,</p>
    Fórmula:C19H18FNO3
    Cor e Forma:Solid
    Peso molecular:327.35
  • 5-HT1AR/5-HT6R ligand-1


    <p>5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.</p>
    Fórmula:C25H29ClN4O2S
    Cor e Forma:Solid
    Peso molecular:485.04
  • AChE-IN-49


    <p>AChE-IN-49 (Compd (S)-7g) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 0.0003 μM.</p>
    Fórmula:C31H28BrClN2O3
    Peso molecular:590.09718
  • SB656104

    CAS:
    <p>SB656104 is a bioactive chemical.</p>
    Fórmula:C25H30ClN3O3S
    Cor e Forma:Solid
    Peso molecular:488.04
  • Laniquidar TFA


    <p>Laniquidar TFA (R101933), a non-competitive P-gp inhibitor, has an IC50 of 0.51 μM; used to study AML and MDS, but with limited bioavailability.</p>
    Fórmula:C39H37F3N4O5
    Pureza:99.85%
    Cor e Forma:Soild
    Peso molecular:698.73
  • Suntinorexton

    CAS:
    <p>Suntinorexton (TAK 861) is an orexin type 2 receptor (OX2R) agonist used in the study of neurologic disorders.</p>
    Fórmula:C23H28F2N2O4S
    Pureza:99.89%
    Cor e Forma:Solid
    Peso molecular:466.54
  • Blestrin D

    CAS:
    <p>Blestrin D: BChE mixed-type inhibitor, IC50=8.1μM, from Bletilla striata, for AD research.</p>
    Fórmula:C30H24O6
    Cor e Forma:Solid
    Peso molecular:480.51
  • epi-Aszonalenin A

    CAS:
    <p>epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.</p>
    Fórmula:C25H25N3O3
    Cor e Forma:Solid
    Peso molecular:415.48
  • MAO-B-IN-4


    <p>MAO-B-IN-4 (Compound 26) is a reversible monoamine oxidase B (MAO-B) inhibitor with potent in vitro activity, characterized by an IC50 value of 9 nM.</p>
    Fórmula:C23H20ClF2N3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:411.87
  • Orexin A (human, rat, mouse) (TFA)


    Endogenous orexin receptor agonist with Ki of 20 nM (OX1) and 38 nM (OX2), promotes feeding, may regulate sleep-wake cycle.
    Fórmula:C154H244N47F3O46S4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3675.12
  • Apoptosis Compound Library


    <p>A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;</p>
    Cor e Forma:Odour Solid
  • LY 293284

    CAS:
    <p>LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.</p>
    Fórmula:C19H26N2O
    Cor e Forma:Solid
    Peso molecular:298.42
  • Pozanicline hydrochloride


    <p>Pozanicline hydrochloride is an oral α4β2 nAChR agonist with a 16.7 nM Ki, insignificantly binding to α7 nAChR.</p>
    Fórmula:C11H17ClN2O
    Pureza:97.13% - 99.81%
    Cor e Forma:Solid
    Peso molecular:228.72
  • N-Desmethyl Pimavanserin

    CAS:
    <p>N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.</p>
    Fórmula:C24H32FN3O2
    Pureza:98.02%
    Cor e Forma:Solid
    Peso molecular:413.53
  • L-AP3

    CAS:
    <p>L-AP3 blocks mGluR, inhibits D/L-phosphoserine (IC50: 368/2087 μM).</p>
    Fórmula:C3H8NO5P
    Cor e Forma:White Hygroscopic Solid
    Peso molecular:169.073
  • Zicronapine fumarate

    CAS:
    <p>Zicronapine fumarate, an antipsychotic, targets D1/D2 &amp; 5-HT2A receptors; may treat neuropsychiatric conditions.</p>
    Fórmula:C26H31ClN2O4
    Cor e Forma:Solid
    Peso molecular:470.99
  • AChE-IN-29


    <p>AChE-IN-29, a 3-OH pyrrolidine derivative, acts as a cholinesterase (ChE) inhibitor with potent activity against human acetylcholinesterase (hAChE), electric</p>
    Fórmula:C18H19BrN2O2
    Cor e Forma:Solid
    Peso molecular:375.26
  • VU6028418

    CAS:
    <p>VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).</p>
    Cor e Forma:Solid
  • Hamaline

    CAS:
    <p>Hamaline (9-(4-chlorobenzyl)-6-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole) is a substrate-selective cyclooxygenase-2 (COX-2) inhibitor.</p>
    Fórmula:C20H19ClN2O
    Pureza:99.88%
    Cor e Forma:Soild
    Peso molecular:338.83
  • (Rac)-5-Hydroxymethyl Tolterodine hydrochloride

    CAS:
    <p>(Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.</p>
    Fórmula:C22H32ClNO2
    Cor e Forma:Solid
    Peso molecular:377.95
  • JF-NP-26


    <p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>
    Cor e Forma:Solid
  • Jatrorrhizine hydroxide

    CAS:
    <p>Jatrorrhizine hydroxide: alkaloid from Coptis chinensis; neuroprotective, antimicrobial, antiplasmodial, antioxidant; AChE inhibitor, affects 5-HT/NE uptake.</p>
    Fórmula:C20H21NO5
    Cor e Forma:Solid
    Peso molecular:355.38
  • Lysyl hydroxylase 2-IN-1


    <p>"Lysyl Hydroxylase 2-IN-1 (compound 12) is a selective inhibitor of lysyl hydroxylase 2 (LH2) with an IC50 of approximately 300 nM and demonstrates specificity</p>
    Fórmula:C18H18N2O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:310.35
  • GAD65(247-266) epitope TFA


    <p>GAD65(247-266) epitope TFA, a T cell epitope derived from islet antigens, exhibits competitive binding to the type I diabetes-associated molecule I-A g7, albeit</p>
    Fórmula:C111H174F3N27O29S4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:2535.99
  • BChE-IN-21


    <p>BChE-IN-21, a potent inhibitor of butyrylcholinesterase (BChE), exhibits an inhibition constant (IC50) of 0.14 ± 0.02 μM, indicating promise for research in</p>
    Cor e Forma:Odour Solid
  • AChE/BChE-IN-15


    <p>AChE/BChE-IN-15 (Compound 6d) serves as an inhibitor for both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), presenting inhibition constants (</p>
    Fórmula:C29H30N6O3
    Cor e Forma:Solid
    Peso molecular:510.59
  • Notch 1 TFA


    <p>Notch 1 TFA encodes a member of the NOTCH family of proteins.</p>
    Fórmula:C64H98N15F3O25S3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1614.81
  • Calmodulin-Dependent Protein Kinase II 290-309 acetate


    <p>Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).</p>
    Fórmula:C105H189N31O26S
    Pureza:96.7%
    Cor e Forma:Solid
    Peso molecular:2333.88
  • Endosulfan I

    CAS:
    <p>Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complex</p>
    Fórmula:C9H6Cl6O3S
    Pureza:99.86%
    Cor e Forma:Solid
    Peso molecular:406.93
  • Xanthohumol I


    <p>Xanthohumol I is a natural product that can be used as a reference standard.</p>
    Fórmula:C21H22O6
    Cor e Forma:Solid
    Peso molecular:370.401
  • DSP-1053

    CAS:
    <p>Dsp-1053 is a powerful SERT (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonizing activity.</p>
    Fórmula:C26H32BrNO4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:502.44
  • TMPH

    CAS:
    <p>TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.</p>
    Fórmula:C16H31NO2
    Pureza:99.78%
    Cor e Forma:Soild
    Peso molecular:269.42
  • Crenezumab

    CAS:
    <p>Crenezumab (MABT 5102A) is a fully humanized anti-amyloid-beta antibody that binds to multiple forms of amyloid-beta (Aβ) for the study of Alzheimer's disease.</p>
    Pureza:97.5% (SDS-PAGE); 95.3% (SEC-HPLC) - 97.5% (SDS-PAGE); 95.3% (SEC-HPLC)
    Cor e Forma:Liquid
  • SSAO inhibitor-1

    CAS:
    <p>SSAO Inhibitor-1 blocks SSAO, has anti-inflammatory effects, used in liver disease research.</p>
    Fórmula:C17H24FN5O2
    Cor e Forma:Solid
    Peso molecular:349.41
  • Pep63

    CAS:
    Pep63, a neuroprotective peptide (VFQVRARTVA), enhances synaptic plasticity and memory. It competitively binds with Aβ1-42 oligomers, thereby inhibiting the formation of Aβ fibrils. Pep63 is employed in research focused on Alzheimer's disease (AD).
    Fórmula:C51H87N17O13
    Peso molecular:1146.34
  • CDD0102 HCl

    CAS:
    <p>CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.</p>
    Fórmula:C8H13ClN4O
    Pureza:99.7%
    Cor e Forma:Soild
    Peso molecular:216.67
  • β-Amyloid (35-25)

    CAS:
    <p>β-Amyloid (35-25) is the reverse sequence of β-Amyloid (25-35).</p>
    Fórmula:C45H81N13O14S
    Peso molecular:1060.27
  • (±)-LY367385

    CAS:
    <p>(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.</p>
    Fórmula:C10H11NO4
    Cor e Forma:Solid
    Peso molecular:209.201
  • (R)-Citalopram oxalate

    CAS:
    <p>(R)-Citalopram oxalate is a weak selective serotonin reuptake inhibitor (SSRI) that antagonises its S-isomer (escitalopram), anticonvulsant and antidepressant</p>
    Fórmula:C22H23FN2O5
    Pureza:99.76%
    Cor e Forma:White Solid
    Peso molecular:414.43
  • COX-2-IN-33


    <p>COX-2-IN-33 (compound 5f) is a selective COX-2 inhibitor with an IC50 value of 45.5 nM and exhibits potential as an anti-inflammatory agent.</p>
    Fórmula:C20H13ClF3N5O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:479.8
  • AC3-I, myristoylated


    <p>Myristoylated AC3-I is a biologically active peptide and a myristoylated variant of the Autocamtide-3-Derived Inhibitory Peptide (AC3-I).</p>
    Fórmula:C78H137N21O20
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1689.05
  • 2'-O-Succinyl-cAMP

    CAS:
    <p>2'-O-Monosuccinyladenosine-3',5'-cyclic monophosphate is an immunogenic derivative of cAMP that has been used to generate anti-cAMP antisera and antibodies.1,2</p>
    Fórmula:C14H16N5O9P
    Cor e Forma:Solid
    Peso molecular:429.282
  • Alosetron

    CAS:
    <p>Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.</p>
    Fórmula:C17H18N4O
    Pureza:98%
    Cor e Forma:Crystalline Powder
    Peso molecular:294.36
  • [Ala11,D-Leu15]-Orexin B(human)

    CAS:
    <p>OX2 receptor agonist with 400x selectivity vs OX1. EC50: 0.13 nM (OX2), 52 nM (OX1).</p>
    Fórmula:C120H206N44O35S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:2857.28
  • Xylamidine

    CAS:
    <p>Xylamidine is a biochemical.</p>
    Fórmula:C19H24N2O2
    Cor e Forma:Solid
    Peso molecular:312.41
  • BuChE-IN-16


    <p>BuChE-IN-16 (Compound 6a) is an orally active, blood-brain barrier-permeable, and selective BuChE inhibitor with an IC50 of 0.33 μM. It exhibits anti-inflammatory and neuroprotective effects, improves cognitive function in Alzheimer's disease (AD) zebrafish models, and alleviates scopolamine-induced memory impairment in mice. BuChE-IN-16 is applicable for Alzheimer's disease research.</p>
    Fórmula:C16H22N2O3
    Cor e Forma:Solid
    Peso molecular:290.36
  • [D-Trp7,9,10]-Substance P

    CAS:
    <p>Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.</p>
    Fórmula:C79H105N21O13S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1588.89
  • (R)-(+)-Anatabine

    CAS:
    <p>(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent agonist of α4β2 nAChR.</p>
    Fórmula:C10H12N2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:160.22
  • α-Conotoxin AuIB

    CAS:
    <p>Selective antagonist of α3β4 nicotinic acetylcholine receptors.</p>
    Fórmula:C65H89N17O21S4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1572.76
  • COX-2-IN-31


    <p>COX-2-IN-31 (compound 7b) is an orally active dual inhibitor targeting COX-2 (IC50=60 nM) and 5-LOX (IC50=1.9 μM).</p>
    Fórmula:C17H16N6O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:400.41
  • Syntide 2 TFA


    Syntide 2 (TFA) is a CaMKII substrate that selectively hinders GA response without affecting other plant processes.
    Fórmula:C70H123N20F3O20
    Cor e Forma:Solid
    Peso molecular:1621.84
  • Anti-inflammatory agent 52


    <p>Anti-inflammatory agent 52 (compound 7j) is an orally active, selective COX-2 inhibitor with the capability to induce G2/M phase arrest and exhibit anti-HT29</p>
    Fórmula:C24H21ClN2O3S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:452.95
  • α5-GABAA receptor modulator 1


    <p>α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.</p>
    Fórmula:C21H20FN3O4
    Cor e Forma:Solid
    Peso molecular:397.4
  • (+)-Coclaurine hydrochloride

    CAS:
    <p>(+)-Coclaurine hydrochloride, also known as (+)-(R)-Coclaurine, is a benzyltetrahydroisoquinoline alkaloid extracted from multiple plant species.</p>
    Fórmula:C17H20ClNO3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:321.8
  • FGIN-1-43

    CAS:
    <p>FGIN-1-43 is a potent and specific ligand for the mitochondrial DBI receptor.</p>
    Fórmula:C28H36Cl2N2O
    Pureza:99.57%
    Cor e Forma:Solid
    Peso molecular:487.5
  • Anticonvulsant agent 8


    <p>Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.</p>
    Fórmula:C15H11N5O
    Cor e Forma:Solid
    Peso molecular:277.28
  • Acetyl-Tau Peptide (273-284) amide

    CAS:
    <p>Acetyl-Tau Peptide (273-284) amide inhibits Ac-Aβ(25–35)-NH2 aggregation and models Aβ/Tau interaction.</p>
    Fórmula:C64H116N18O17
    Cor e Forma:Solid
    Peso molecular:1409.72
  • β-Secretase Inhibitor I

    CAS:
    <p>β-Secretase Inhibitor I is a highly potent inhibitor of the β-secretase enzyme.</p>
    Fórmula:C18H18F3N5O2S
    Cor e Forma:Solid
    Peso molecular:425.43
  • Quetiapine-d4 fumarate

    CAS:
    <p>Deuterium-labeled Quetiapine fumarate; an antidepressant and anxiolytic 5-HT agonist, dopamine antagonist.</p>
    Fórmula:C25H29N3O6S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:503.61
  • MAOA-IN-1


    <p>MAOA-IN-1 (compound 15) is an orally-active inhibitor of monoamine oxidase A (MAOA) that exhibits cytotoxic effects on prostate cancer cells.</p>
    Fórmula:C13H16Cl2N2O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:303.18
  • IHC3


    <p>IHC3 is a competitive and reversible monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.672 μM, which targets Cys172 within the enzyme's active site.</p>
    Fórmula:C17H12FN3O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:293.3
  • Rasagiline 13C3 mesylate racemic

    CAS:
    <p>Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor.</p>
    Fórmula:C13H17NO3S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:270.32
  • N-Ethyl-N-(3-pyridylmethyl)amine

    CAS:
    <p>N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.</p>
    Fórmula:C8H12N2
    Pureza:99.65%
    Cor e Forma:Solid
    Peso molecular:136.19
  • Substance P(1-4) Acetate


    <p>Substance P(1-4) Acetate is a neurokinin receptor (NK-R) antagonist, inhibiting the formation of PV EEC.</p>
    Fórmula:C24H44N8O7
    Pureza:99.84%
    Cor e Forma:Solid
    Peso molecular:556.66
  • Fasciculic acid B

    CAS:
    <p>Fasciculic acid B: ester of fasciculol B, 3-hydroxy-methylglutaric acid; a calmodulin antagonist from Naematoloma fasciculare.</p>
    Fórmula:C36H60O9
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:636.86
  • AChE/BChE-IN-13


    <p>AChE/BChE-IN-13 (compound 5j) serves as a potent dual inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting half-maximal</p>
    Fórmula:C21H18N8O7
    Cor e Forma:Solid
    Peso molecular:494.42
  • Fezolamine

    CAS:
    <p>Fezolamine: a new, non-tricyclic, oral antidepressant, selectively inhibits norepinephrine uptake over serotonin or dopamine.</p>
    Fórmula:C20H23N3
    Pureza:99.33%
    Cor e Forma:Solid
    Peso molecular:305.42
  • (Iso)-Atagabalin HCl

    CAS:
    <p>(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.</p>
    Fórmula:C10H20ClNO2
    Pureza:99.26% - >99.99%
    Cor e Forma:Soild
    Peso molecular:221.72
  • Histamine & Melatonin Receptor-Targeted Compound Library


    <p>A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS</p>
    Cor e Forma:Odour Solid
  • PZ-1922


    <p>PZ-1922 (Compound 16), able to cross the blood-brain barrier, is a dual antagonist for 5-HT6R and 5-HT3R with K i values of 17 nM and 0.45 nM, respectively.</p>
    Pureza:98%
    Cor e Forma:Odour Solid
  • β-Amyloid (10-20)

    CAS:
    <p>Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-</p>
    Fórmula:C71H99N17O16
    Pureza:98%
    Cor e Forma:Lyophilized Powder
    Peso molecular:1446.65
  • Calmodulin Kinase IINtide, Myristoylated


    <p>Myristoylated Calmodulin Kinase IINtide (Myr-CaMKIINtide) serves as a selective and noncompetitive inhibitor of CaMKII [1].</p>
    Fórmula:C156H275N47O43
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3497.14
  • SPL-707

    CAS:
    <p>SPL-707 is an effective and selective signal peptide peptidase-like 2a inhibitor (IC50: 80 nM).</p>
    Fórmula:C27H28FN5O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:505.54
  • Monoamine oxidase

    CAS:
    <p>Enzyme that breaks down amines in the brain and body, affecting mood and brain function.</p>
    Cor e Forma:Solid
  • (Met(O)35)-Amyloid β-Protein (1-42)


    <p>(Met(O)35)-Amyloid β-Protein (1-42) represents the oxidized form of Methionine 35 in Aβ42, capable of producing an oligomer size distribution akin to that of</p>
    Fórmula:C203H311N55O61S
    Cor e Forma:Solid
    Peso molecular:4530.04
  • (rel)-Asperparaline A

    CAS:
    <p>Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.</p>
    Fórmula:C20H29N3O3
    Cor e Forma:Solid
    Peso molecular:359.47
  • Imagabalin

    CAS:
    <p>Imagabalin is an active compound used in the study of neurological diseases.</p>
    Fórmula:C9H19NO2
    Cor e Forma:Solid
    Peso molecular:173.25
  • Proadrenomedullin (1-20), human

    CAS:
    <p>Endogenous peptide; agonist of MRGPRX2 (EC50=251 nM); noncompetitive inhibitor of nicotinic receptors; reduces catecholamine secretion; antihypertensive.</p>
    Fórmula:C112H178N36O27
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:2460.84
  • Antidepressant agent 5

    CAS:
    <p>Antidepressant agent 5 is a 7-substituted tetrahydroisoquinoline derivative with antidepressant activity.Antidepressant agent 5 acts similarly to magnoflorine</p>
    Fórmula:C20H25NO3
    Pureza:99.34%
    Cor e Forma:Soild
    Peso molecular:327.42
  • OXA(17-33)

    CAS:
    <p>Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.</p>
    Fórmula:C79H125N23O22
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1749
  • RA306


    <p>RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.</p>
    Cor e Forma:Odour Solid
  • STX-107

    CAS:
    <p>STX-107 is a potent and selective mGluR5 agonist for the study of Fragile X Syndrome.</p>
    Fórmula:C18H10FN3S
    Pureza:99.17%
    Cor e Forma:Solid
    Peso molecular:319.36
  • BuChE-IN-11


    <p>BuChE-IN-11 (Compound 3b-1) is a selective inhibitor of BuChE with an IC50 of 0.44 μM for hBuChE. The compound demonstrates high brain-blood barrier permeability and possesses free radical scavenging capabilities, indicating significant antioxidant activity. BuChE-IN-11 interacts with the choline binding site, the acyl binding site, and the peripheral anionic site, showing submicromolar inhibitory activity against BuChE and preventing the self-aggregation of β-amyloid protein (Aβ). This compound holds promise for research in the field of Alzheimer's disease.</p>
    Fórmula:C28H27FN4O2
    Peso molecular:470.2118
  • MAO-B-IN-3


    <p>MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a Ki</p>
    Fórmula:C24H25N3O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:387.47
  • Sulamserod

    CAS:
    <p>Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular related</p>
    Fórmula:C19H28ClN3O5S
    Pureza:98.76%
    Cor e Forma:Solid
    Peso molecular:445.96
  • PF-03382792

    CAS:
    <p>PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.</p>
    Fórmula:C23H32FN3O4
    Pureza:99.64%
    Cor e Forma:Solid
    Peso molecular:433.52
  • CPN-267 TFA


    <p>CPN-267 (compound 7b) TFA is a selective agonist of neuromedin U receptor 1 (NMUR1) with an EC50 of 0.25 nM. This compound inhibits weight gain in mice and is applicable in obesity research.</p>
    Fórmula:C54H68F6N16O12S
    Cor e Forma:Solid
    Peso molecular:1279.27
  • Eletriptan

    CAS:
    <p>Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.</p>
    Fórmula:C22H26N2O2S
    Cor e Forma:Solid
    Peso molecular:382.52
  • Atagabalin

    CAS:
    <p>Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.</p>
    Fórmula:C10H19NO2
    Cor e Forma:Solid
    Peso molecular:185.26