
Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(939 produtos)
- ACK(1 produtos)
- AChR(575 produtos)
- ATP Citrato Liase(16 produtos)
- Receptor adrenérgico(2.945 produtos)
- BACE(36 produtos)
- Beta Amilóide(205 produtos)
- CaMK(69 produtos)
- COX(561 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor GABA(336 produtos)
- Gama-secretase(59 produtos)
- GluR(255 produtos)
- GlyT(24 produtos)
- Receptor de Histamina(358 produtos)
- LRRK2(33 produtos)
- Receptor de Melatonina(24 produtos)
- NMDAR(28 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(297 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5398 produtos de "Neurociência"
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β-Amyloid (22-35)
CAS:<p>β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells.</p>Fórmula:C59H102N16O21SPureza:98%Cor e Forma:SolidPeso molecular:1403.62(Rac)-Norcisapride
CAS:<p>Norcisapride, a 5-HT3 and 5-HT4 agonist, treats GI, orofacial, and ENT disorders.</p>Fórmula:C14H20ClN3O3Pureza:99.32%Cor e Forma:SoildPeso molecular:313.78MIDD0301
CAS:<p>MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.</p>Fórmula:C19H13BrFN3O2Pureza:98%Cor e Forma:SolidPeso molecular:414.23Anticonvulsant agent 9
<p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>Fórmula:C22H24N4O2Cor e Forma:SolidPeso molecular:376.45β-Amyloid (35-42)
CAS:<p>β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.</p>Fórmula:C33H60N8O9SPureza:98%Cor e Forma:SolidPeso molecular:744.94Lanuginosine
CAS:<p>Lanuginosine, an aporphine alkaloid, exhibits cytotoxicity against U251.</p>Fórmula:C18H11NO4Cor e Forma:SolidPeso molecular:305.28CaMKIIα-PHOTAC
<p>CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα).</p>Fórmula:C54H58Cl2N10O11Pureza:98%Cor e Forma:SolidPeso molecular:1094NMDA receptor antagonist 8
<p>Compound (R)-10a, an NMDA receptor antagonist, exhibits selectivity for the GluN2B subunit, possessing a Ki of 265 nM and an IC50 of 62 nM.</p>Fórmula:C22H27N3OPureza:98%Cor e Forma:SolidPeso molecular:349.475-HT6R antagonist 1
<p>Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stability</p>Fórmula:C17H22F2N6OPureza:98%Cor e Forma:SolidPeso molecular:364.39Nardoguaianone J
CAS:<p>Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].</p>Fórmula:C15H22O2Cor e Forma:SolidPeso molecular:234.33CUR-IPA
<p>CUR-IPA is a cholinesterase inhibitor with IC50 values of 5.99 μM for eAChE (electric eel), 59.30 μM for hAChE (human), and 60.66 μM for hBChE (human). It has free radical scavenging and antioxidant activity and is useful for researching cognitive dysfunction.</p>Fórmula:C43H38N2O8Cor e Forma:SolidPeso molecular:710.77AChE/BuChE/MAO-B-IN-2
<p>AChE/BuChE/MAO-B-IN-2 (compound 4b) is a potent inhibitor of AChE, BuChE, and hu MAO-B, with respective IC50 values of 5.3 μM, 12.4 μM, and 1.9±0.08 μM,</p>Fórmula:C19H18FNO3Cor e Forma:SolidPeso molecular:327.355-HT1AR/5-HT6R ligand-1
<p>5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.</p>Fórmula:C25H29ClN4O2SCor e Forma:SolidPeso molecular:485.04AChE-IN-49
<p>AChE-IN-49 (Compd (S)-7g) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 0.0003 μM.</p>Fórmula:C31H28BrClN2O3Peso molecular:590.09718SB656104
CAS:<p>SB656104 is a bioactive chemical.</p>Fórmula:C25H30ClN3O3SCor e Forma:SolidPeso molecular:488.04Laniquidar TFA
<p>Laniquidar TFA (R101933), a non-competitive P-gp inhibitor, has an IC50 of 0.51 μM; used to study AML and MDS, but with limited bioavailability.</p>Fórmula:C39H37F3N4O5Pureza:99.85%Cor e Forma:SoildPeso molecular:698.73Suntinorexton
CAS:<p>Suntinorexton (TAK 861) is an orexin type 2 receptor (OX2R) agonist used in the study of neurologic disorders.</p>Fórmula:C23H28F2N2O4SPureza:99.89%Cor e Forma:SolidPeso molecular:466.54Blestrin D
CAS:<p>Blestrin D: BChE mixed-type inhibitor, IC50=8.1μM, from Bletilla striata, for AD research.</p>Fórmula:C30H24O6Cor e Forma:SolidPeso molecular:480.51epi-Aszonalenin A
CAS:<p>epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.</p>Fórmula:C25H25N3O3Cor e Forma:SolidPeso molecular:415.48MAO-B-IN-4
<p>MAO-B-IN-4 (Compound 26) is a reversible monoamine oxidase B (MAO-B) inhibitor with potent in vitro activity, characterized by an IC50 value of 9 nM.</p>Fórmula:C23H20ClF2N3Pureza:98%Cor e Forma:SolidPeso molecular:411.87Orexin A (human, rat, mouse) (TFA)
Endogenous orexin receptor agonist with Ki of 20 nM (OX1) and 38 nM (OX2), promotes feeding, may regulate sleep-wake cycle.Fórmula:C154H244N47F3O46S4Pureza:98%Cor e Forma:SolidPeso molecular:3675.12Apoptosis Compound Library
<p>A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;</p>Cor e Forma:Odour SolidLY 293284
CAS:<p>LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.</p>Fórmula:C19H26N2OCor e Forma:SolidPeso molecular:298.42Pozanicline hydrochloride
<p>Pozanicline hydrochloride is an oral α4β2 nAChR agonist with a 16.7 nM Ki, insignificantly binding to α7 nAChR.</p>Fórmula:C11H17ClN2OPureza:97.13% - 99.81%Cor e Forma:SolidPeso molecular:228.72N-Desmethyl Pimavanserin
CAS:<p>N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.</p>Fórmula:C24H32FN3O2Pureza:98.02%Cor e Forma:SolidPeso molecular:413.53L-AP3
CAS:<p>L-AP3 blocks mGluR, inhibits D/L-phosphoserine (IC50: 368/2087 μM).</p>Fórmula:C3H8NO5PCor e Forma:White Hygroscopic SolidPeso molecular:169.073Zicronapine fumarate
CAS:<p>Zicronapine fumarate, an antipsychotic, targets D1/D2 & 5-HT2A receptors; may treat neuropsychiatric conditions.</p>Fórmula:C26H31ClN2O4Cor e Forma:SolidPeso molecular:470.99AChE-IN-29
<p>AChE-IN-29, a 3-OH pyrrolidine derivative, acts as a cholinesterase (ChE) inhibitor with potent activity against human acetylcholinesterase (hAChE), electric</p>Fórmula:C18H19BrN2O2Cor e Forma:SolidPeso molecular:375.26VU6028418
CAS:<p>VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).</p>Cor e Forma:SolidHamaline
CAS:<p>Hamaline (9-(4-chlorobenzyl)-6-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole) is a substrate-selective cyclooxygenase-2 (COX-2) inhibitor.</p>Fórmula:C20H19ClN2OPureza:99.88%Cor e Forma:SoildPeso molecular:338.83(Rac)-5-Hydroxymethyl Tolterodine hydrochloride
CAS:<p>(Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.</p>Fórmula:C22H32ClNO2Cor e Forma:SolidPeso molecular:377.95JF-NP-26
<p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>Cor e Forma:SolidJatrorrhizine hydroxide
CAS:<p>Jatrorrhizine hydroxide: alkaloid from Coptis chinensis; neuroprotective, antimicrobial, antiplasmodial, antioxidant; AChE inhibitor, affects 5-HT/NE uptake.</p>Fórmula:C20H21NO5Cor e Forma:SolidPeso molecular:355.38Lysyl hydroxylase 2-IN-1
<p>"Lysyl Hydroxylase 2-IN-1 (compound 12) is a selective inhibitor of lysyl hydroxylase 2 (LH2) with an IC50 of approximately 300 nM and demonstrates specificity</p>Fórmula:C18H18N2O3Pureza:98%Cor e Forma:SolidPeso molecular:310.35GAD65(247-266) epitope TFA
<p>GAD65(247-266) epitope TFA, a T cell epitope derived from islet antigens, exhibits competitive binding to the type I diabetes-associated molecule I-A g7, albeit</p>Fórmula:C111H174F3N27O29S4Pureza:98%Cor e Forma:SolidPeso molecular:2535.99BChE-IN-21
<p>BChE-IN-21, a potent inhibitor of butyrylcholinesterase (BChE), exhibits an inhibition constant (IC50) of 0.14 ± 0.02 μM, indicating promise for research in</p>Cor e Forma:Odour SolidAChE/BChE-IN-15
<p>AChE/BChE-IN-15 (Compound 6d) serves as an inhibitor for both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), presenting inhibition constants (</p>Fórmula:C29H30N6O3Cor e Forma:SolidPeso molecular:510.59Notch 1 TFA
<p>Notch 1 TFA encodes a member of the NOTCH family of proteins.</p>Fórmula:C64H98N15F3O25S3Pureza:98%Cor e Forma:SolidPeso molecular:1614.81Calmodulin-Dependent Protein Kinase II 290-309 acetate
<p>Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).</p>Fórmula:C105H189N31O26SPureza:96.7%Cor e Forma:SolidPeso molecular:2333.88Endosulfan I
CAS:<p>Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complex</p>Fórmula:C9H6Cl6O3SPureza:99.86%Cor e Forma:SolidPeso molecular:406.93Xanthohumol I
<p>Xanthohumol I is a natural product that can be used as a reference standard.</p>Fórmula:C21H22O6Cor e Forma:SolidPeso molecular:370.401DSP-1053
CAS:<p>Dsp-1053 is a powerful SERT (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonizing activity.</p>Fórmula:C26H32BrNO4Pureza:98%Cor e Forma:SolidPeso molecular:502.44TMPH
CAS:<p>TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.</p>Fórmula:C16H31NO2Pureza:99.78%Cor e Forma:SoildPeso molecular:269.42Crenezumab
CAS:<p>Crenezumab (MABT 5102A) is a fully humanized anti-amyloid-beta antibody that binds to multiple forms of amyloid-beta (Aβ) for the study of Alzheimer's disease.</p>Pureza:97.5% (SDS-PAGE); 95.3% (SEC-HPLC) - 97.5% (SDS-PAGE); 95.3% (SEC-HPLC)Cor e Forma:LiquidSSAO inhibitor-1
CAS:<p>SSAO Inhibitor-1 blocks SSAO, has anti-inflammatory effects, used in liver disease research.</p>Fórmula:C17H24FN5O2Cor e Forma:SolidPeso molecular:349.41Pep63
CAS:Pep63, a neuroprotective peptide (VFQVRARTVA), enhances synaptic plasticity and memory. It competitively binds with Aβ1-42 oligomers, thereby inhibiting the formation of Aβ fibrils. Pep63 is employed in research focused on Alzheimer's disease (AD).Fórmula:C51H87N17O13Peso molecular:1146.34CDD0102 HCl
CAS:<p>CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.</p>Fórmula:C8H13ClN4OPureza:99.7%Cor e Forma:SoildPeso molecular:216.67β-Amyloid (35-25)
CAS:<p>β-Amyloid (35-25) is the reverse sequence of β-Amyloid (25-35).</p>Fórmula:C45H81N13O14SPeso molecular:1060.27(±)-LY367385
CAS:<p>(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.</p>Fórmula:C10H11NO4Cor e Forma:SolidPeso molecular:209.201(R)-Citalopram oxalate
CAS:<p>(R)-Citalopram oxalate is a weak selective serotonin reuptake inhibitor (SSRI) that antagonises its S-isomer (escitalopram), anticonvulsant and antidepressant</p>Fórmula:C22H23FN2O5Pureza:99.76%Cor e Forma:White SolidPeso molecular:414.43COX-2-IN-33
<p>COX-2-IN-33 (compound 5f) is a selective COX-2 inhibitor with an IC50 value of 45.5 nM and exhibits potential as an anti-inflammatory agent.</p>Fórmula:C20H13ClF3N5O4Pureza:98%Cor e Forma:SolidPeso molecular:479.8AC3-I, myristoylated
<p>Myristoylated AC3-I is a biologically active peptide and a myristoylated variant of the Autocamtide-3-Derived Inhibitory Peptide (AC3-I).</p>Fórmula:C78H137N21O20Pureza:98%Cor e Forma:SolidPeso molecular:1689.052'-O-Succinyl-cAMP
CAS:<p>2'-O-Monosuccinyladenosine-3',5'-cyclic monophosphate is an immunogenic derivative of cAMP that has been used to generate anti-cAMP antisera and antibodies.1,2</p>Fórmula:C14H16N5O9PCor e Forma:SolidPeso molecular:429.282Alosetron
CAS:<p>Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.</p>Fórmula:C17H18N4OPureza:98%Cor e Forma:Crystalline PowderPeso molecular:294.36[Ala11,D-Leu15]-Orexin B(human)
CAS:<p>OX2 receptor agonist with 400x selectivity vs OX1. EC50: 0.13 nM (OX2), 52 nM (OX1).</p>Fórmula:C120H206N44O35SPureza:98%Cor e Forma:SolidPeso molecular:2857.28Xylamidine
CAS:<p>Xylamidine is a biochemical.</p>Fórmula:C19H24N2O2Cor e Forma:SolidPeso molecular:312.41BuChE-IN-16
<p>BuChE-IN-16 (Compound 6a) is an orally active, blood-brain barrier-permeable, and selective BuChE inhibitor with an IC50 of 0.33 μM. It exhibits anti-inflammatory and neuroprotective effects, improves cognitive function in Alzheimer's disease (AD) zebrafish models, and alleviates scopolamine-induced memory impairment in mice. BuChE-IN-16 is applicable for Alzheimer's disease research.</p>Fórmula:C16H22N2O3Cor e Forma:SolidPeso molecular:290.36[D-Trp7,9,10]-Substance P
CAS:<p>Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.</p>Fórmula:C79H105N21O13SPureza:98%Cor e Forma:SolidPeso molecular:1588.89(R)-(+)-Anatabine
CAS:<p>(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent agonist of α4β2 nAChR.</p>Fórmula:C10H12N2Pureza:98%Cor e Forma:SolidPeso molecular:160.22α-Conotoxin AuIB
CAS:<p>Selective antagonist of α3β4 nicotinic acetylcholine receptors.</p>Fórmula:C65H89N17O21S4Pureza:98%Cor e Forma:SolidPeso molecular:1572.76COX-2-IN-31
<p>COX-2-IN-31 (compound 7b) is an orally active dual inhibitor targeting COX-2 (IC50=60 nM) and 5-LOX (IC50=1.9 μM).</p>Fórmula:C17H16N6O4SPureza:98%Cor e Forma:SolidPeso molecular:400.41Syntide 2 TFA
Syntide 2 (TFA) is a CaMKII substrate that selectively hinders GA response without affecting other plant processes.Fórmula:C70H123N20F3O20Cor e Forma:SolidPeso molecular:1621.84Anti-inflammatory agent 52
<p>Anti-inflammatory agent 52 (compound 7j) is an orally active, selective COX-2 inhibitor with the capability to induce G2/M phase arrest and exhibit anti-HT29</p>Fórmula:C24H21ClN2O3SPureza:98%Cor e Forma:SolidPeso molecular:452.95α5-GABAA receptor modulator 1
<p>α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.</p>Fórmula:C21H20FN3O4Cor e Forma:SolidPeso molecular:397.4(+)-Coclaurine hydrochloride
CAS:<p>(+)-Coclaurine hydrochloride, also known as (+)-(R)-Coclaurine, is a benzyltetrahydroisoquinoline alkaloid extracted from multiple plant species.</p>Fórmula:C17H20ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:321.8FGIN-1-43
CAS:<p>FGIN-1-43 is a potent and specific ligand for the mitochondrial DBI receptor.</p>Fórmula:C28H36Cl2N2OPureza:99.57%Cor e Forma:SolidPeso molecular:487.5Anticonvulsant agent 8
<p>Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.</p>Fórmula:C15H11N5OCor e Forma:SolidPeso molecular:277.28Acetyl-Tau Peptide (273-284) amide
CAS:<p>Acetyl-Tau Peptide (273-284) amide inhibits Ac-Aβ(25–35)-NH2 aggregation and models Aβ/Tau interaction.</p>Fórmula:C64H116N18O17Cor e Forma:SolidPeso molecular:1409.72β-Secretase Inhibitor I
CAS:<p>β-Secretase Inhibitor I is a highly potent inhibitor of the β-secretase enzyme.</p>Fórmula:C18H18F3N5O2SCor e Forma:SolidPeso molecular:425.43Quetiapine-d4 fumarate
CAS:<p>Deuterium-labeled Quetiapine fumarate; an antidepressant and anxiolytic 5-HT agonist, dopamine antagonist.</p>Fórmula:C25H29N3O6SPureza:98%Cor e Forma:SolidPeso molecular:503.61MAOA-IN-1
<p>MAOA-IN-1 (compound 15) is an orally-active inhibitor of monoamine oxidase A (MAOA) that exhibits cytotoxic effects on prostate cancer cells.</p>Fórmula:C13H16Cl2N2O2Pureza:98%Cor e Forma:SolidPeso molecular:303.18IHC3
<p>IHC3 is a competitive and reversible monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.672 μM, which targets Cys172 within the enzyme's active site.</p>Fórmula:C17H12FN3OPureza:98%Cor e Forma:SolidPeso molecular:293.3Rasagiline 13C3 mesylate racemic
CAS:<p>Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor.</p>Fórmula:C13H17NO3SPureza:98%Cor e Forma:SolidPeso molecular:270.32N-Ethyl-N-(3-pyridylmethyl)amine
CAS:<p>N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.</p>Fórmula:C8H12N2Pureza:99.65%Cor e Forma:SolidPeso molecular:136.19Substance P(1-4) Acetate
<p>Substance P(1-4) Acetate is a neurokinin receptor (NK-R) antagonist, inhibiting the formation of PV EEC.</p>Fórmula:C24H44N8O7Pureza:99.84%Cor e Forma:SolidPeso molecular:556.66Fasciculic acid B
CAS:<p>Fasciculic acid B: ester of fasciculol B, 3-hydroxy-methylglutaric acid; a calmodulin antagonist from Naematoloma fasciculare.</p>Fórmula:C36H60O9Pureza:98%Cor e Forma:SolidPeso molecular:636.86AChE/BChE-IN-13
<p>AChE/BChE-IN-13 (compound 5j) serves as a potent dual inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting half-maximal</p>Fórmula:C21H18N8O7Cor e Forma:SolidPeso molecular:494.42Fezolamine
CAS:<p>Fezolamine: a new, non-tricyclic, oral antidepressant, selectively inhibits norepinephrine uptake over serotonin or dopamine.</p>Fórmula:C20H23N3Pureza:99.33%Cor e Forma:SolidPeso molecular:305.42(Iso)-Atagabalin HCl
CAS:<p>(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.</p>Fórmula:C10H20ClNO2Pureza:99.26% - >99.99%Cor e Forma:SoildPeso molecular:221.72Histamine & Melatonin Receptor-Targeted Compound Library
<p>A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS</p>Cor e Forma:Odour SolidPZ-1922
<p>PZ-1922 (Compound 16), able to cross the blood-brain barrier, is a dual antagonist for 5-HT6R and 5-HT3R with K i values of 17 nM and 0.45 nM, respectively.</p>Pureza:98%Cor e Forma:Odour Solidβ-Amyloid (10-20)
CAS:<p>Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-</p>Fórmula:C71H99N17O16Pureza:98%Cor e Forma:Lyophilized PowderPeso molecular:1446.65Calmodulin Kinase IINtide, Myristoylated
<p>Myristoylated Calmodulin Kinase IINtide (Myr-CaMKIINtide) serves as a selective and noncompetitive inhibitor of CaMKII [1].</p>Fórmula:C156H275N47O43Pureza:98%Cor e Forma:SolidPeso molecular:3497.14SPL-707
CAS:<p>SPL-707 is an effective and selective signal peptide peptidase-like 2a inhibitor (IC50: 80 nM).</p>Fórmula:C27H28FN5O4Pureza:98%Cor e Forma:SolidPeso molecular:505.54Monoamine oxidase
CAS:<p>Enzyme that breaks down amines in the brain and body, affecting mood and brain function.</p>Cor e Forma:Solid(Met(O)35)-Amyloid β-Protein (1-42)
<p>(Met(O)35)-Amyloid β-Protein (1-42) represents the oxidized form of Methionine 35 in Aβ42, capable of producing an oligomer size distribution akin to that of</p>Fórmula:C203H311N55O61SCor e Forma:SolidPeso molecular:4530.04(rel)-Asperparaline A
CAS:<p>Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.</p>Fórmula:C20H29N3O3Cor e Forma:SolidPeso molecular:359.47Imagabalin
CAS:<p>Imagabalin is an active compound used in the study of neurological diseases.</p>Fórmula:C9H19NO2Cor e Forma:SolidPeso molecular:173.25Proadrenomedullin (1-20), human
CAS:<p>Endogenous peptide; agonist of MRGPRX2 (EC50=251 nM); noncompetitive inhibitor of nicotinic receptors; reduces catecholamine secretion; antihypertensive.</p>Fórmula:C112H178N36O27Pureza:98%Cor e Forma:SolidPeso molecular:2460.84Antidepressant agent 5
CAS:<p>Antidepressant agent 5 is a 7-substituted tetrahydroisoquinoline derivative with antidepressant activity.Antidepressant agent 5 acts similarly to magnoflorine</p>Fórmula:C20H25NO3Pureza:99.34%Cor e Forma:SoildPeso molecular:327.42OXA(17-33)
CAS:<p>Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.</p>Fórmula:C79H125N23O22Pureza:98%Cor e Forma:SolidPeso molecular:1749RA306
<p>RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.</p>Cor e Forma:Odour SolidSTX-107
CAS:<p>STX-107 is a potent and selective mGluR5 agonist for the study of Fragile X Syndrome.</p>Fórmula:C18H10FN3SPureza:99.17%Cor e Forma:SolidPeso molecular:319.36BuChE-IN-11
<p>BuChE-IN-11 (Compound 3b-1) is a selective inhibitor of BuChE with an IC50 of 0.44 μM for hBuChE. The compound demonstrates high brain-blood barrier permeability and possesses free radical scavenging capabilities, indicating significant antioxidant activity. BuChE-IN-11 interacts with the choline binding site, the acyl binding site, and the peripheral anionic site, showing submicromolar inhibitory activity against BuChE and preventing the self-aggregation of β-amyloid protein (Aβ). This compound holds promise for research in the field of Alzheimer's disease.</p>Fórmula:C28H27FN4O2Peso molecular:470.2118MAO-B-IN-3
<p>MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a Ki</p>Fórmula:C24H25N3O2Pureza:98%Cor e Forma:SolidPeso molecular:387.47Sulamserod
CAS:<p>Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular related</p>Fórmula:C19H28ClN3O5SPureza:98.76%Cor e Forma:SolidPeso molecular:445.96PF-03382792
CAS:<p>PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.</p>Fórmula:C23H32FN3O4Pureza:99.64%Cor e Forma:SolidPeso molecular:433.52CPN-267 TFA
<p>CPN-267 (compound 7b) TFA is a selective agonist of neuromedin U receptor 1 (NMUR1) with an EC50 of 0.25 nM. This compound inhibits weight gain in mice and is applicable in obesity research.</p>Fórmula:C54H68F6N16O12SCor e Forma:SolidPeso molecular:1279.27Eletriptan
CAS:<p>Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.</p>Fórmula:C22H26N2O2SCor e Forma:SolidPeso molecular:382.52Atagabalin
CAS:<p>Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.</p>Fórmula:C10H19NO2Cor e Forma:SolidPeso molecular:185.26

