Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.024 produtos)
- ACK(1 produtos)
- AChR(624 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.029 produtos)
- BACE(36 produtos)
- Beta Amilóide(224 produtos)
- CaMK(73 produtos)
- COX(600 produtos)
- Receptor de Dopamina(443 produtos)
- Receptor GABA(365 produtos)
- Gama-secretase(62 produtos)
- GluR(263 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(42 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(42 produtos)
- Receptor opioide(326 produtos)
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Foram encontrados 5559 produtos de "Neurociência"
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Azocarnil
Azocarnil is a GABAergic agonist-enhancer used in neurological system research.Cor e Forma:Odour SolidNeuronal Signaling Compound Library
A unique collection of xnum compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;Cor e Forma:Odour SolidRef: TM-L2600
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarRocuronium
CAS:Rocuronium is an blocker of aminosteroid non-depolarizing neuromuscular.Fórmula:C32H53N2O4Pureza:98%Cor e Forma:SolidPeso molecular:529.77Lupanine perchlorate
CAS:Lupanine perchlorate is a bioactive chemical.Fórmula:C15H25ClN2O5Cor e Forma:SolidPeso molecular:348.825-HT2C agonist-4
CAS:Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.Fórmula:C24H25N5OCor e Forma:SolidPeso molecular:399.49AAK1-IN-11
AAK1-IN-11 is an inhibitor of AAK1 (adaptor associated kinase 1) with an IC50 of 2 nM, and it exhibits antiviral activity.Cor e Forma:Odour SolidNeuroprotective Compound Library
<p>A unique collection of xnum bioactive small molecules with neuroprotective relevance for high throughput screening (HTS) and high content screening (HCS);</p>Cor e Forma:Odour SolidbPiDDB
CAS:<p>bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.</p>Fórmula:C24H38Br2N2Pureza:98.72%Cor e Forma:SolidPeso molecular:514.38CIA-1 (Free base)
CAS:CIA-1, a COUP-TFII inhibitor, has IC50 of 1.2-7.6 μM in prostate cancer cells; inhibits tumor growth in mouse prostate cancer.Fórmula:C17H19N3O2SPureza:99%Cor e Forma:SolidPeso molecular:329.42hAChE-IN-3
hAChE-IN-3 (compound 5c) serves as a potent inhibitor for AChE, BuChE, MAO-B, and BACE-1, with respective IC50 values of 0.44, 0.08, 5.15, and 0.38 μM,Fórmula:C30H24ClN3O5Pureza:98%Cor e Forma:SolidPeso molecular:541.98Anti-inflammatory agent 53
Anti-inflammatory agent 52 (compound 7c) is an orally active, selective COX-2 inhibitor with demonstrated anti-HT29 metastatic activity, causing periodic arrestFórmula:C24H22N2O4SPureza:98%Cor e Forma:SolidPeso molecular:434.5112,14-Dichlorodehydroabietic acid
CAS:12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.Fórmula:C20H26Cl2O2Cor e Forma:SolidPeso molecular:369.33Fipronil sulfone
CAS:Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.Fórmula:C12H4Cl2F6N4O2SPureza:98%Cor e Forma:SolidPeso molecular:453.14DOAM
CAS:DOAM is an antagonist of the 5-HT2 receptor.Fórmula:C16H27NO2Cor e Forma:SolidPeso molecular:265.394-Methoxyphenyl isothiocyanate
CAS:4-Methoxyphenyl isothiocyanate (4-Methylphenyl ITC) is recognized as an antioxidant demonstrating an IC50 of 1.25 mM for scavenging DPPH free radicals. Its antioxidant capacity, as shown by the ORAC test, is 11.7 mM TE, equivalent to the efficacy of 11.7 mmol Trolox under similar conditions. Additionally, it extends the oxidation process in the Briggs–Rauscher reaction by approximately 9180 seconds. The compound also exhibits moderate cholinesterase inhibitory activity, with an inhibition rate of 30.4% for acetylcholinesterase (AChE) and 17.9% for butyrylcholinesterase (BChE). Research suggests 4-Methoxyphenyl isothiocyanate holds promise for applications in antioxidant and neurological disorder studies.Fórmula:C8H7NOSCor e Forma:SolidPeso molecular:165.21NPS ALX Compound 4a hydrochloride(1:1)
NPS ALX Compound 4a hydrochloride(1:1) is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.Fórmula:C25H26ClN3O2SPureza:99.84%Cor e Forma:SoildPeso molecular:468.01Ref: TM-T12262L1
1mg40,00€5mg88,00€10mg119,00€25mg198,00€50mg288,00€100mg393,00€200mg520,00€1mL*10mM (DMSO)97,00€(Rac)-Oleoylcarnitine
CAS:(Rac)-Oleoylcarnitine, an endogenous acylcarnitine, acts as a potential non-competitive inhibitor of glycine transporter 2 (GLYT2) and can be used as a pain suppressant.Fórmula:C25H47NO4Peso molecular:425.65Sodium Channel Targeted Library
A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;Cor e Forma:Odour SolidRef: TM-L7400
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarOrg 24598 lithium salt
CAS:Org 24598 lithium salt is a GlyT-1 inhibitor of glycine transporter 1.Fórmula:C19H19F3LiNO3Cor e Forma:SolidPeso molecular:373.3CC-3240
CAS:CC-3240 (compound 13), a molecular glue degrader of CaMKK2 based on CC-8977, has an IC50 of 9 nM [1].Fórmula:C52H64N6O7SPeso molecular:917.17Chrodrimanin B
CAS:Chrodrimanin B is a useful organic compound for research related to life sciences. The catalog number is T126052 and the CAS number is 132196-54-4.Fórmula:C27H32O8Cor e Forma:SolidPeso molecular:484.545Galanin (1-15) (porcine, rat)
CAS:N-terminal galanin fragment used to mediate central cardiovascular effectsFórmula:C72H105N19O20Pureza:98%Cor e Forma:SolidPeso molecular:1556.72BChE-IN-39
BChE-IN-39 (Compound 7c) selectively inhibits butyrylcholinesterase (BChE) with an IC50 of 0.08 μM, while showing an IC50 of 3.98 μM for acetylcholinesterase (AChE) inhibition. Additionally, BChE-IN-39 downregulates GSK-3β expression, thereby inhibiting the excessive phosphorylation of tau protein.Fórmula:C29H23ClFN3O3Cor e Forma:SolidPeso molecular:515.963Pellotine
CAS:Pellotine is an alkaloid isolated from Lophophora. It acts as an inverse agonist of the 5-HT7 receptor (5-HT7 receptor), with an EC50 of 291 nM. Pellotine shows strong affinity for the 5-HT1DR and 5-HT6R, with Ki values of 117 nM and 170 nM, respectively. Additionally, Pellotine reduces intracellular cAMP levels, thereby decreasing neuronal excitability and neurotransmitter release.Fórmula:C13H19NO3Cor e Forma:SolidPeso molecular:237.295Pyridostigmine bromide
CAS:Pyridostigmine bromide (Mestinon), a cholinesterase inhibitor, is used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants.Fórmula:C9H13BrN2O2Pureza:99.00% - 99.98%Cor e Forma:White Or Practically White Crystalline Powder Pale Yellow To Colorless LiquidPeso molecular:261.12Tropicamide
CAS:Tropicamide (Ro 1-7683), a synthetic atropine-like muscarinic antagonist, dilates pupils and paralyzes eye muscles for diagnostic use.Fórmula:C17H20N2O2Pureza:99.78% - 99.94%Cor e Forma:White PowderPeso molecular:284.35(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS:(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.Fórmula:C6H11NO2Cor e Forma:SolidPeso molecular:129.16Arisugacin G
CAS:Arisugacin G, a microbial metabolite, is a structural analogue of Arisugacin A. Unlike its analogue, Arisugacin G does not exhibit activity against AChE (acetylcholinesterase).Fórmula:C27H32O5Cor e Forma:SolidPeso molecular:436.54Mesoridazine Besylate
CAS:Mesoridazine Besylate (Serentil), a piperidine antipsychotic and phenothiazine, treats schizophrenia; it's a thioridazine metabolite.Fórmula:C27H32N2O4S3Pureza:98.87%Cor e Forma:SolidPeso molecular:544.75DAA-1106
CAS:DAA-1106 is a potent and selective ligand for PBR, acting as a potent and selective agonist at the peripheral benzodiazepine receptor.Fórmula:C23H22FNO4Pureza:99.54%Cor e Forma:SolidPeso molecular:395.42AChE/BChE-IN-14
AChE/BChE-IN-14 (compound 13), a benzylisoquinoline alkaloid extracted from Fissistigma polyanthum roots, demonstrates inhibitory effects on bothFórmula:C19H23NO3Cor e Forma:SolidPeso molecular:313.39COX-2-IN-46
COX-2-IN-46 (compound 5m) serves as a potent anti-inflammatory and analgesic agent. It demonstrates a significant inhibitory action on COX-2, with an IC 50 value of 87.74 nM.Fórmula:C28H19F2N3SCor e Forma:SolidPeso molecular:467.53SB 258585
CAS:SB 258585: Selective 5-HT6 antagonist, binds human receptors, used in cognitive and antipsychotic assays.Fórmula:C18H22IN3O3SPureza:99.77%Cor e Forma:SoildPeso molecular:487.36CPN-267
CAS:CPN-267 (compound 7b) acts as a selective agonist for the neuromediatin U receptor 1 (NMUR1), exhibiting an EC50 value of 0.25 nM. It effectively inhibits weight gain in mice, making it useful for obesity research.Fórmula:C50H66N16O8SPeso molecular:1051.23(-)-Eseroline fumarate
CAS:(-)-Eseroline fumarate, a Physostigmine metabolite and AChE inhibitor, triggers cancer cell LDH release and neuronal cell death.Fórmula:C17H22N2O5Cor e Forma:SolidPeso molecular:334.375-methoxy-α-Ethyltryptamine
CAS:<p>5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects. </p>Fórmula:C13H18N2OPureza:98.25%Cor e Forma:SolidPeso molecular:218.29Chrysophanol-1-O-β-gentiobioside
CAS:Chrysophanol-1-O-β-gentiobioside, an anthraquinone glycoside obtained from the seeds of Cassia obtusifolia, exhibits targeted inhibition of hMAO-A isozymeFórmula:C27H30O14Cor e Forma:SolidPeso molecular:578.52Triazolomethylindole-3-acetic acid
CAS:Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.Fórmula:C13H12N4O2Cor e Forma:SolidPeso molecular:256.26ACHE Inhibitor 12
CAS:<p>ACHE Inhibitor 12 inhibited acetylcholinesterase with an IC50 value of 0.38 µM.</p>Fórmula:C11H12OPureza:98.71%Cor e Forma:SolidPeso molecular:160.21LY3020371
CAS:LY3020371: potent, selective mGlu 2/3 receptor antagonist with Ki of 5.26 nM (hmGluR2) and 2.50 nM (hmGluR3); key in depression studies.Fórmula:C15H15F2NO5SCor e Forma:SolidPeso molecular:359.34Methalthiazide
CAS:Methalthiazide enhances the activity of natural agonists of AMPA receptors and can be utilized in schizophrenia research.Fórmula:C12H16ClN3O4S3Cor e Forma:SolidPeso molecular:397.926,7-dimethylisatin
CAS:6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.Fórmula:C10H9NO2Pureza:98.98%Cor e Forma:SolidPeso molecular:175.18Tryptamine hydrochloride
CAS:<p>Tryptamine hydrochloride is a monoamine alkaloid, metabolite of tryptophan and CNS active substance, agonist of 5-HT4 receptor, TAAR1, AHR.</p>Fórmula:C10H13ClN2Pureza:99.89%Cor e Forma:SolidPeso molecular:196.68Zanapezil free base
CAS:Zanapezil (TAK-147): potent, selective AChE inhibitor; reversible; IC50=51.2 nM; moderate M1/M2 inhibition; AD research potential.Fórmula:C25H32N2OCor e Forma:SolidPeso molecular:376.5442-Methyl-N,N-dimethyltryptamine
CAS:2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.Fórmula:C13H18N2Cor e Forma:SolidPeso molecular:202.35-HT6R antagonist 1
Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stabilityFórmula:C17H22F2N6OPureza:98%Cor e Forma:SolidPeso molecular:364.39GRGDSPK acetate
CAS:GRGDSPK acetate shows inhibitory activity against integrin-fibronectin binding and can be used in research on integrins in bone formation and resorption.Fórmula:C30H53N11O13Pureza:97.9%Cor e Forma:SoildPeso molecular:775.81β-Secretase inhibitor-STA
CAS:<p>BACE-IN-1 is amyloid precursor protein beta-secretase inhibitor</p>Fórmula:C73H118N16O27Pureza:98%Cor e Forma:SolidPeso molecular:1651.815-AAM-2-CP
CAS:5-AAM-2-CP is one of the major metabolites of Acetamiprid. Acetamiprid, a nAChR agonist, is a neonicotinoid insecticide used worldwide.Fórmula:C8H9ClN2OPureza:99.58%Cor e Forma:SolidPeso molecular:184.62CALP2
CAS:CALP2 is a CaM antagonist blocking EF-hand/Ca2+ site; inhibits CaM phosphodiesterase, raises Ca2+, and activates alveolar macrophages.Fórmula:C68H104N14O13SPureza:98%Cor e Forma:SolidPeso molecular:1357.72Cannabidiolic acid methyl ester
CAS:Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.Fórmula:C23H32O4Cor e Forma:SolidPeso molecular:372.5Deoxynojirimycin Tetrabenzyl Ether
CAS:Deoxynojirimycin tetrabenzyl ether aids in making 1-dNM, a strong α-glucosidase I & II blocker.Fórmula:C34H37NO4Cor e Forma:SolidPeso molecular:523.6734-Iodoamphetamine hydrochloride
CAS:4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated phenethylamine characterized by the presence of an iodine atom at the para position of the phenyl group. It selectively induces serotonin release and inhibits reuptake in rat brain synaptosomes.Fórmula:C9H13ClINCor e Forma:SolidPeso molecular:297.56Pikamilone Sodium
CAS:Pikamilone Sodium is a prodrug of GABA used for therapy of neurogenic bladder in spinal and benign prostatic hyperplasia.Fórmula:C10H11N2NaO3Pureza:98%Cor e Forma:SolidPeso molecular:230.2Antipsychotic agent-2
Compound 11: potent antipsychotic, binds 5-HT1A/2A/2C, D2, H1 receptors; K is 56.6-1140 nM, BBB permeable.Fórmula:C22H26FN5OCor e Forma:SolidPeso molecular:395.475-HT2A receptor agonist-5
CAS:5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.Fórmula:C23H29N3OCor e Forma:SolidPeso molecular:363.5Paynantheine
CAS:Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.Fórmula:C23H28N2O4Cor e Forma:SolidPeso molecular:396.48β-Amyloid (1-28)
CAS:β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.Fórmula:C145H209N41O46Pureza:98%Cor e Forma:SolidPeso molecular:3262.51sabcomeline
CAS:Sabcomeline: potent, selective M1 agonist; boosts cognition; for Alzheimer's study.Fórmula:C10H15N3OCor e Forma:SolidPeso molecular:193.25Metixene
CAS:Metixene is an anticholinergic drug. It was developed as a treatment against Parkinson's disease.Fórmula:C20H23NSCor e Forma:LiquidPeso molecular:309.47R 50595
CAS:R 50595 is a selective non-competitive cisapride antagonist.Fórmula:C30H35Cl2F2N3O3Pureza:98%Cor e Forma:SolidPeso molecular:594.52Nitrazolam
CAS:Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.Fórmula:C17H13N5O2Cor e Forma:SolidPeso molecular:319.32NT 13 acetate
NT 13 acetate is a partial agonist of NMDA receptor and can be used for research on depression, anxiety, and other related diseases.Fórmula:C20H34N4O9Pureza:98%Cor e Forma:SolidPeso molecular:474.51TAT-CN21
TatCN21, with an IC 50 of 77 nM, serves as a potent and selective inhibitor peptide of the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase. It is particularly useful in research pertaining to ischemia and neurodegenerative diseases.Fórmula:C169H303N69O43Cor e Forma:SolidPeso molecular:3989.65Cisapride hydrate
CAS:Cisapride acts directly as a selective agonist of serotonin 5-HT4 receptor with IC50 value of 0.483 μM. And It also acts indirectly as a parasympathomimetic.Fórmula:C23H31ClFN3O5Pureza:98%Cor e Forma:SolidPeso molecular:483.96mGluR5 modulator 1
CAS:mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.Fórmula:C18H19ClFN3O2Cor e Forma:SolidPeso molecular:363.82LE 300
CAS:LE 300 represents a structurally novel type of antagonists acting preferentially at the dopamine D(1)/D(5)receptors and the serotonin 5-HT(2A)receptor.Fórmula:C20H22N2Pureza:97.91% - 98.79%Cor e Forma:SolidPeso molecular:290.4BRD9 ligand-6
CAS:BRD9 ligand-6 serves as a ligand for the target protein in PROTAC applications. It is utilized in the synthesis of FHD-609.Fórmula:C21H21N3O4Cor e Forma:SolidPeso molecular:379.41Guanylyl Imidodiphosphate (lithium salt)
CAS:Guanylyl Imidodiphosphate (lithium salt) is a non-hydrolyzable GTP analog that increases adenylate cyclase activity.Fórmula:C10H13Li4N6O13P3Cor e Forma:SolidPeso molecular:545.93AChE-IN-49
<p>AChE-IN-49 (Compd (S)-7g) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 0.0003 μM.</p>Fórmula:C31H28BrClN2O3Peso molecular:590.09718γ-Secretase Modulators
CAS:gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β.Fórmula:C26H24F3N3O3Pureza:98%Cor e Forma:SolidPeso molecular:483.48Profenofos
CAS:Profenofos is an organophosphate insecticide used in cotton and vegetables. that causes neurotoxicity through the inhibition of AChE activity.Fórmula:C11H15BrClO3PSPureza:97.04% - 97.24%Cor e Forma:SolidPeso molecular:373.631-(2-Methoxyphenyl)piperazine hydrochloride
CAS:Compound PDK0265, with CAS No. 5464-78-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0265 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C11H16N2OPeso molecular:192.25TET-13
TET-13 is a positive allosteric modulator of the GABAA receptor with an EC50 of 5.65 μM, which is more potent than Etomidate (EC50: 9.29 μM). It exhibits strong anesthetic effects in both mice and rats, with an ED50 of 0.48 mg/kg in mice and 0.69 mg/kg in rats.Fórmula:C15H16N2O3SCor e Forma:SolidPeso molecular:304.36Alosetron
CAS:Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.Fórmula:C17H18N4OPureza:98%Cor e Forma:Crystalline PowderPeso molecular:294.36Dihydrochalcone
CAS:Compound PDK0018, with CAS No. 1083-30-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0018 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C15H14OPeso molecular:210.27(S)-AMPA HCl
(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.Fórmula:C7H11ClN2O4Pureza:99.18%Cor e Forma:SolidPeso molecular:222.63SD-254
CAS:SD-254 is a deuterium analog of Effexor, with fewer side effects and a longer half-life.Fórmula:C17H27NO2Peso molecular:286.465-(2-Aminopropyl)indole
CAS:5-(2-Aminopropyl)indole is an orally active psychoactive substance that inhibits monoamine oxidase (MAO) and exhibits long-lasting stimulant effects.Fórmula:C11H14N2Cor e Forma:SolidPeso molecular:174.24Melatonin-Tamoxifen Conjugate
Melatonin-Tamoxifen Conjugate (compound 16c) is an anticancer drug conjugate made of Melatonin and Tamoxifen, serving as an effective antagonist of ERα (IC50 = 863 nM). In cells expressing the hMT1 receptor, it binds to MLT receptors (Ki = 3.1 nM) and exhibits the ability to promote β-arrestin activation (EC50 = 914 nM) and ERK activation (EC50 = 98 nM). The IC50 values for Melatonin-Tamoxifen Conjugate in MCF-7, MDA-MB-231, and HT-1080 cell lines are 6.8 μM, 6.4 μM, and 1.7 μM, respectively.Fórmula:C47H58N4O4Cor e Forma:SolidPeso molecular:742.99Methylatropine (nitrate)
CAS:Methylatropine: Muscarinic antagonist, <0.1 nM IC50, atropine derivative, lowers ACh's effect on BP, affects salivation, pupil dilation, heart rate.Fórmula:C18H26N2O6Cor e Forma:SolidPeso molecular:366.414Emraclidine
CAS:Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.Fórmula:C20H21F3N4OPureza:99.96%Cor e Forma:SolidPeso molecular:390.4Ref: TM-T9694
1mg127,00€2mgA consultar5mg305,00€10mg494,00€25mg882,00€50mg1.198,00€100mg1.586,00€1mL*10mM (DMSO)338,00€Lon 954
CAS:Lon 954, also known as Harmine, is a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds.Fórmula:C9H10Cl3N3OCor e Forma:SolidPeso molecular:282.55TRV-7019
CAS:TRV-7019: BBB-permeable radioligand for brain imaging, used in diagnosing amyloid diseases, MS, and brain tumors.Fórmula:C14H12INO3Cor e Forma:SolidPeso molecular:369.15BChE-IN-16
BChE-IN-16 (compound 87) is a potent inhibitor of human butyrylcholinesterase (hBChE) exhibiting an inhibition concentration half-maximum (IC50) of 3.8 nM.Fórmula:C28H32FNO2Cor e Forma:SolidPeso molecular:433.565-Hydroxymethyl tolterodine formate
CAS:5-Hydroxymethyl tolterodine (formate) (PNU-200577 (formic)) is an active metabolite of the muscarinic acetylcholine receptor antagonists Tolterodine and Fesoterodine. It is synthesized by the cytochrome P450 (CYP) isoenzyme CYP2D6 and plasma esterases.Fórmula:C23H33NO4Cor e Forma:SolidPeso molecular:387.512,3-Dehydrosilybin A
CAS:2,3-Dehydrosilybin A is a useful organic compound for research related to life sciences and the catalog number is T125202.Fórmula:C25H20O10Cor e Forma:SolidPeso molecular:480.43(S,S)-BMS-984923
CAS:(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 >1μM; less active than its potent counterpart.Fórmula:C22H15ClN2O2Cor e Forma:SolidPeso molecular:374.82Emamectin B1a
CAS:<p>Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.</p>Fórmula:C49H75NO13Cor e Forma:SolidPeso molecular:886.133CDD0102 HCl
CAS:CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.Fórmula:C8H13ClN4OPureza:99.7%Cor e Forma:SoildPeso molecular:216.67DISC-0974
DISC-0974 is a humanized antibody targeting RGMC/HFE2, which can be used to study urogenital system diseases.Cor e Forma:LiquidPeso molecular:145.66 kDaSKF-83566 hydrochloride
CAS:SKF-83566 hydrochloride is a D1-like dopamine receptor antagonist, inhibiting dopamine transporters and mitigating GBP-induced CPP.Fórmula:C17H19BrClNOPureza:99.27%Cor e Forma:SoildPeso molecular:368.69SQ-3
SQ-3, a quinoline analogue, prefers α-syn (Ki=39.3nM) to Aβ (Ki=230nM), and [18F]SQ3 is a lead for α-syn probes. [1]Fórmula:C21H21FN2OCor e Forma:SolidPeso molecular:336.4Methyl ganoderate A acetonide
CAS:Methyl ganoderate A from Ganoderma lucidum is a natural AChE inhibitor (IC50=18.35 μM) for Alzheimer's research.Fórmula:C34H50O7Cor e Forma:SolidPeso molecular:570.76Serazapine
CAS:<p>Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.</p>Fórmula:C22H23N3O2Pureza:98.71% - 99.57%Cor e Forma:SolidPeso molecular:361.44Rilmazolam
CAS:Rilmazolam is a triazolobenzodiazepine compound and serves as the active metabolite of Rilmazafone.Fórmula:C19H15Cl2N5OCor e Forma:SolidPeso molecular:400.26Tampramine
CAS:<p>Tampramine: a TCA and selective norepinephrine inhibitor, with low affinity for other receptors, potential treatment for FST depression.</p>Fórmula:C23H24N4Pureza:99.87%Cor e Forma:SolidPeso molecular:356.46Vortioxetine D8
CAS:Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).Fórmula:C18H22N2SPureza:98%Cor e Forma:SolidPeso molecular:306.5COX-1-IN-2
COX-1-IN-2 (compound 5h) serves as a potent anti-inflammatory and analgesic agent. This compound demonstrates a significant inhibitory effect on COX-1, with an IC 50 value of 38.76 nM.Fórmula:C29H22FN3OSCor e Forma:SolidPeso molecular:479.57[Ala2,8,9,11,19,22,24,25,27,28]-VIP
CAS:[Ala2,8,9,11,19,22,24,25,27,28]-VIP can be used for related research in the field of life sciences. Its product number is T36637 and CAS number is 866552-34-3.Fórmula:C131H219N41O33SCor e Forma:SolidPeso molecular:2928.51
![[Ala2,8,9,11,19,22,24,25,27,28]-VIP](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT36637.webp&w=3840&q=75)