Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.024 produtos)
- ACK(1 produtos)
- AChR(626 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.030 produtos)
- BACE(36 produtos)
- Beta Amilóide(225 produtos)
- CaMK(73 produtos)
- COX(601 produtos)
- Receptor de Dopamina(443 produtos)
- Receptor GABA(366 produtos)
- Gama-secretase(62 produtos)
- GluR(263 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(42 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(9 produtos)
- Receptor OX(42 produtos)
- Receptor opioide(326 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5546 produtos de "Neurociência"
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2-Hydroxyalbrassitriol
CAS:2-Hydroxyalbrassitriol (Compound 6) is an AChE inhibitor with an IC 50 of 35.97 μM [1] .Fórmula:C15H26O4Cor e Forma:SolidPeso molecular:270.36Osmanthuside B
CAS:Osmanthuside B, isolated from Pseuderanthemum carruthersii (Seem.) Guill.Fórmula:C29H36O13Cor e Forma:SolidPeso molecular:592.59HDAC6-IN-49
HDAC6-IN-49 (Compound 3) is an inhibitor of HDAC, with IC50 values of 0.012 and 0.735 µM against HDAC6 and HDAC1, respectively. Additionally, it inhibits MAO-B, cholinesterase (ChE), histamine receptor (H3R), and serotonin 6 receptor (5-HT6R). HDAC6-IN-49 exhibits neuroprotective effects in SH-SY5Y cells and enhances cognitive functions and motor abilities in fruit fly models of Parkinson's disease and C. elegans models of Alzheimer's disease.Cor e Forma:Odour SolidMant-GTPγS
CAS:Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.Fórmula:C18H23N6O14P3SCor e Forma:SolidPeso molecular:672.39Tiflucarbine
CAS:Tiflucarbine is a potential non-selective 5-HT agonist with antidepressant activity.Tiflucarbine dose-dependently increased the specific activity of solubleFórmula:C16H17FN2SPureza:97.71%Cor e Forma:SolidPeso molecular:288.38Stacofylline
CAS:Stacofylline is a xanthine derivative that is used to treat migraine headaches.Fórmula:C20H33N7O3Pureza:99.43% - 99.85%Cor e Forma:SolidPeso molecular:419.52Velnacrine
CAS:<p>Velnacrine (1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate) is a biochemical.</p>Fórmula:C13H14N2OPureza:99.83%Cor e Forma:SolidPeso molecular:214.26β-Amyloid Protein Precursor 770 (135-155)
CAS:<p>Beta-Amyloid Protein Precursor 770 (135-155)Aβ Protein Precursor 770 (135-155)</p>Fórmula:C116H172N35O31S2Pureza:98%Cor e Forma:SolidPeso molecular:2617.965-AMAM-2-CP
CAS:5-AMAM-2-CP, a significant metabolite of Acetamiprid, serves as a global insecticide within the neonicotinoid class and acts as an nAChR agonist [1] [2].Fórmula:C9H11ClN2OCor e Forma:SolidPeso molecular:198.65Neocarzinostatin
CAS:Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.Pureza:98%Cor e Forma:SolidPeso molecular:N/ADonitriptan hydrochloride
CAS:Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectivelyFórmula:C23H26ClN5O2Pureza:99.8% - 99.86%Cor e Forma:SolidPeso molecular:439.94Ref: TM-T21666
2mg40,00€5mg49,00€10mg64,00€25mg135,00€50mg240,00€100mg339,00€200mg439,00€500mgA consultarTropicamide
CAS:Tropicamide (Ro 1-7683), a synthetic atropine-like muscarinic antagonist, dilates pupils and paralyzes eye muscles for diagnostic use.Fórmula:C17H20N2O2Pureza:99.78% - 99.94%Cor e Forma:White PowderPeso molecular:284.35β-Amyloid (33-40)
CAS:β-Amyloid (33-40) is a peptide comprising amino acids 33 to 40 of the beta-amyloid protein.Fórmula:C32H58N8O9SPureza:98%Cor e Forma:SolidPeso molecular:730.92Exosome Compound Library
<p>76 exosome-related compounds that can be used for high-throughput and high-content screening.</p>Cor e Forma:Odour SolidPF-03382792
CAS:PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.Fórmula:C23H32FN3O4Pureza:99.64%Cor e Forma:SolidPeso molecular:433.52Cianopramine hydrochloride
CAS:Cianopramine hydrochloride is a bio-active chemical.Fórmula:C20H24ClN3Cor e Forma:SolidPeso molecular:341.88Potassium Channel Targeted Library
A unique collection of xnum potassium channel blockers and agonists for high throughput and high content screening;Cor e Forma:Odour SolidRef: TM-L7300
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarTetrahydro-β-carboline
CAS:Compound Fr12161, with CAS No. 16502-01-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12161 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C11H12N2Pureza:96.31%Cor e Forma:Tan SolidPeso molecular:172.2264Histamine & Melatonin Receptor-Targeted Compound Library
<p>A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS</p>Cor e Forma:Odour SolidFezolamine
CAS:Fezolamine: a new, non-tricyclic, oral antidepressant, selectively inhibits norepinephrine uptake over serotonin or dopamine.Fórmula:C20H23N3Pureza:99.86%Cor e Forma:SolidPeso molecular:305.42Neurotransmitter Receptor Compound Library
<p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；</p>Cor e Forma:Odour SolidSerotonin Receptor-Targeted Compound Library
A unique collection of xnum compounds targeting serotonin receptors for high throughput screening and high content screening;Cor e Forma:Odour SolidRef: TM-L2800
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarPD07
PD07 is an orally active acetylcholinesterase (AChE) inhibitor, exhibiting an IC50 of 0.29 μM against human AChE, and demonstrates inhibition of cholinesterasesFórmula:C23H21ClN2O4Cor e Forma:SolidPeso molecular:424.88β-Amyloid (1-40)
CAS:Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.Fórmula:C194H295N53O58SPureza:98%Cor e Forma:SolidPeso molecular:4329.82Ion Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Cor e Forma:Odour SolidTZ4M
TZ4M, a 2,4-thiazolidinedione (TZD)-based anti-ADV agent, exhibits neuroprotective effects and acetylcholinesterase (AChE) inhibition in human plasma.Fórmula:C19H15NO4SCor e Forma:SolidPeso molecular:353.391-Ethyl-1H-indole
CAS:1-Ethyl-1H-indole exhibits inhibitory activity against AChE (IC₅₀ = 101 µM) and can be used in related research in the field of life sciences.Fórmula:C10H11NPureza:98.80%Cor e Forma:SolidPeso molecular:145.2Calcium Channel Compound Library
A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;Cor e Forma:Odour SolidRef: TM-L7200
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarCNS-Penetrant Compound Library
<p>A unique collection of 509 CNS-Penetrant compounds for high throughput screening (HTS) and high content screening (HCS);</p>Cor e Forma:Odour Solidβ-Amyloid (4-10)
CAS:Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances inFórmula:C39H52N12O12Pureza:98%Cor e Forma:SolidPeso molecular:880.9Neural Regeneration Compound Library
<p>A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening;</p>Cor e Forma:Odour SolidMinesapride
CAS:<p>Minesapride: novel 5-HT4 partial agonist, may treat constipation-predominant IBS.</p>Fórmula:C21H31ClN4O5Pureza:99.85% - 99.88%Cor e Forma:SolidPeso molecular:454.95Apoptosis Compound Library
A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;Cor e Forma:Odour SolidRef: TM-L9000
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarβ-Amyloid (12-28)
CAS:Amyloid β-peptide fragment; minimum section required to bind to brain proteins.Fórmula:C89H135N25O25Pureza:98%Cor e Forma:SolidPeso molecular:1955.18PF-06827443
PF-06827443 is a orally bioavailable, CNS-penetrant M1-selective PAM with minimal agonist activity.Fórmula:C24H24N2O4Cor e Forma:SolidPeso molecular:404.47(+)-OSU 6162
CAS:(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.Fórmula:C15H23NO2SPureza:98.19%Cor e Forma:SoildPeso molecular:281.41Ref: TM-T60027
1mg77,00€5mg155,00€10mg220,00€25mg338,00€50mg472,00€100mg632,00€200mg853,00€1mL*10mM (DMSO)163,00€BACE1-IN-15
BACE1-IN-15 (Compound 72) is a selective β-secretase 1 (BACE-1) inhibitor with oral bioavailability and blood-brain barrier permeability, exhibiting an IC50 value of 121.65 nM, and an IC50 of 480.92 nM for BACE-2. BACE1-IN-15 is applicable for research in the field of Alzheimer's disease.Cor e Forma:Odour Solid1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS:<p>1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.</p>Fórmula:C10H12N2O2SPureza:99.96%Cor e Forma:SoildPeso molecular:224.28Aducanumab
CAS:<p>Aducanumab (BIIB037) is an IgG1 antibody targeting amyloid beta to treat Alzheimer's; it's brain-permeable.</p>Pureza:95% - 97.10%Cor e Forma:LiquidPeso molecular:145.93 kDa3-Aminopropylphosphonic Acid
CAS:<p>3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding</p>Fórmula:C3H10NO3PPureza:99.84%Cor e Forma:Light Yellow LiquidPeso molecular:139.09Neuronal Signaling Compound Library
A unique collection of xnum compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;Cor e Forma:Odour SolidRef: TM-L2600
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarSodium Channel Targeted Library
A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;Cor e Forma:Odour SolidRef: TM-L7400
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarRo 12-5637
CAS:Ro 12-5637 is a metabolite of moclobemide.Fórmula:C13H17ClN2O3Cor e Forma:SolidPeso molecular:284.74α-Conotoxin PIA TFA
α-Conotoxin PIA TFA, targeting nicotinic acetylcholine receptor (nAChR) subtypes with α6 and α3 subunits, acts as an antagonist.Fórmula:C81H126F3N27O27S4Pureza:98.81%Cor e Forma:SolidPeso molecular:2095.3Biperiden Hydrochloride
CAS:Biperiden HCl is an anti-Parkinson's drug, blocks M1 receptors, manages all Parkinson's types, and is FDA-approved. Non-toxic at 0.11 mg/kg to rats' cognition.Fórmula:C21H30ClNOPureza:98%Cor e Forma:SolidPeso molecular:347.92Neuroprotective Compound Library
<p>A unique collection of xnum bioactive small molecules with neuroprotective relevance for high throughput screening (HTS) and high content screening (HCS);</p>Cor e Forma:Odour Solid5β-Cholanic acid
CAS:<p>5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.</p>Fórmula:C24H40O2Pureza:98.91% - 99.89%Cor e Forma:SoildPeso molecular:360.57Lanuginosine
CAS:Lanuginosine, an aporphine alkaloid, exhibits cytotoxicity against U251.Fórmula:C18H11NO4Cor e Forma:SolidPeso molecular:305.28Mosapride citrate dihydrate
CAS:<p>Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.</p>Fórmula:C27H35ClFN3O11Pureza:98%Cor e Forma:SolidPeso molecular:632.04Pozanicline hydrochloride
Pozanicline hydrochloride is an oral α4β2 nAChR agonist with a 16.7 nM Ki, insignificantly binding to α7 nAChR.Fórmula:C11H17ClN2OPureza:97.13% - 99.81%Cor e Forma:SolidPeso molecular:228.72Ref: TM-T16563L
1mg77,00€5mg155,00€10mg220,00€25mg338,00€50mg472,00€100mg632,00€200mg853,00€1mL*10mM (DMSO)134,00€CIA-1 (Free base)
CAS:CIA-1, a COUP-TFII inhibitor, has IC50 of 1.2-7.6 μM in prostate cancer cells; inhibits tumor growth in mouse prostate cancer.Fórmula:C17H19N3O2SPureza:99%Cor e Forma:SolidPeso molecular:329.42GRGDSPK acetate
CAS:GRGDSPK acetate shows inhibitory activity against integrin-fibronectin binding and can be used in research on integrins in bone formation and resorption.Fórmula:C30H53N11O13Pureza:97.9%Cor e Forma:SoildPeso molecular:775.81β-Secretase inhibitor-STA
CAS:<p>BACE-IN-1 is amyloid precursor protein beta-secretase inhibitor</p>Fórmula:C73H118N16O27Pureza:98%Cor e Forma:SolidPeso molecular:1651.81BU 226 hydrochloride
CAS:BU 226 hydrochloride demonstrates affinity for imidazoline (I) receptors, in particular the I2 binding site with a Ki of 1.4 nM.Fórmula:C12H12ClN3Pureza:99.67%Cor e Forma:SolidPeso molecular:233.75-HT6R antagonist 1
Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stabilityFórmula:C17H22F2N6OPureza:98%Cor e Forma:SolidPeso molecular:364.39Calmodulin-Dependent Protein Kinase II (281-309)
CAS:Calmodulin-Dependent Protein Kinase II (281-309) is a synthetic peptide that can be phosphorylated at Thr286 by PKC and inhibits CaM kinase II (IC50 = 80 nM).Fórmula:C146H254N46O39S3Pureza:98%Cor e Forma:SolidPeso molecular:3374.06LY836
LY836 is an orally active, neuroprotective compound that effectively inhibits the PSD95-nNOS association in cortical neurons.Pureza:98%Cor e Forma:Odour SolidCOX-1/2-IN-4
COX-1/2-IN-4 (compound 2b) is a dual COX-1 and COX-2 inhibitor with respective IC50 values of 0.239 μM for COX-1 and 0.191 μM for COX-2.Fórmula:C22H24N2O2SPureza:98%Cor e Forma:SolidPeso molecular:380.5NMDA receptor antagonist 8
Compound (R)-10a, an NMDA receptor antagonist, exhibits selectivity for the GluN2B subunit, possessing a Ki of 265 nM and an IC50 of 62 nM.Fórmula:C22H27N3OPureza:98%Cor e Forma:SolidPeso molecular:349.47MmTx1 toxin
Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor's sensitivity to its agonist [1].Fórmula:C295H455N95O97S10Pureza:98%Cor e Forma:SolidPeso molecular:7205CaMKIIα-PHOTAC
CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα).Fórmula:C54H58Cl2N10O11Pureza:98%Cor e Forma:SolidPeso molecular:1094MAO-B-IN-4
MAO-B-IN-4 (Compound 26) is a reversible monoamine oxidase B (MAO-B) inhibitor with potent in vitro activity, characterized by an IC50 value of 9 nM.Fórmula:C23H20ClF2N3Pureza:98%Cor e Forma:SolidPeso molecular:411.87Lysyl hydroxylase 2-IN-1
"Lysyl Hydroxylase 2-IN-1 (compound 12) is a selective inhibitor of lysyl hydroxylase 2 (LH2) with an IC50 of approximately 300 nM and demonstrates specificityFórmula:C18H18N2O3Pureza:98%Cor e Forma:SolidPeso molecular:310.35NMDA receptor antagonist 7
Compound (S)-10a, a GluN2B subunit-selective NMDA receptor antagonist, exhibits a K i of 93 nM and an IC 50 of 72 nM.Fórmula:C22H27N3OPureza:98%Cor e Forma:SolidPeso molecular:349.47Fabesetron
CAS:<p>Fabesetron (FK1052): oral dual antagonist for 5-HT3/5-HT4 receptors. Aids in managing acute and delayed chemo-induced emesis.</p>Fórmula:C18H19N3OCor e Forma:SolidPeso molecular:293.37Aloveroside A
CAS:Aloveroside A, a triglucosylnaphthalene derivative extracted from Aloe vera using ethanol, exhibits modest inhibitory activity against bACE, demonstratingFórmula:C30H40O17Cor e Forma:SolidPeso molecular:672.63Tampramine
CAS:<p>Tampramine: a TCA and selective norepinephrine inhibitor, with low affinity for other receptors, potential treatment for FST depression.</p>Fórmula:C23H24N4Pureza:99.87%Cor e Forma:SolidPeso molecular:356.46α-Casozepine
CAS:α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.Fórmula:C60H94N14O16Cor e Forma:SolidPeso molecular:1267.47LBG20304
LBG20304 (compound 2s) serves as a ligand for the homologous GluK5 receptor, demonstrating an IC50 of 432 nM and exhibiting over 40-fold selectivity against the GluK1-3 isoforms. At concentrations below 10 μM, LBG20304 shows neither agonistic nor antagonistic effects on heterologous GluK2/5 receptors. However, at concentrations above 10 μM, it displays minimal agonist activity in neuronal slices (rat).Fórmula:C19H18N4O5Cor e Forma:SolidPeso molecular:382.37COX-2-IN-46
COX-2-IN-46 (compound 5m) serves as a potent anti-inflammatory and analgesic agent. It demonstrates a significant inhibitory action on COX-2, with an IC 50 value of 87.74 nM.Fórmula:C28H19F2N3SCor e Forma:SolidPeso molecular:467.53Calmodulin Kinase IINtide, Myristoylated
Myristoylated Calmodulin Kinase IINtide (Myr-CaMKIINtide) serves as a selective and noncompetitive inhibitor of CaMKII [1].Fórmula:C156H275N47O43Pureza:98%Cor e Forma:SolidPeso molecular:3497.14TAT-CN21
TatCN21, with an IC 50 of 77 nM, serves as a potent and selective inhibitor peptide of the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase. It is particularly useful in research pertaining to ischemia and neurodegenerative diseases.Fórmula:C169H303N69O43Cor e Forma:SolidPeso molecular:3989.65COX-1-IN-2
COX-1-IN-2 (compound 5h) serves as a potent anti-inflammatory and analgesic agent. This compound demonstrates a significant inhibitory effect on COX-1, with an IC 50 value of 38.76 nM.Fórmula:C29H22FN3OSCor e Forma:SolidPeso molecular:479.57Anti-inflammatory agent 52
Anti-inflammatory agent 52 (compound 7j) is an orally active, selective COX-2 inhibitor with the capability to induce G2/M phase arrest and exhibit anti-HT29Fórmula:C24H21ClN2O3SPureza:98%Cor e Forma:SolidPeso molecular:452.95COX-2-IN-31
COX-2-IN-31 (compound 7b) is an orally active dual inhibitor targeting COX-2 (IC50=60 nM) and 5-LOX (IC50=1.9 μM).Fórmula:C17H16N6O4SPureza:98%Cor e Forma:SolidPeso molecular:400.41NMDAR antagonist 2
NMDAR antagonist 2 (compound 3I) is a blood-brain barrier permeable antagonist of NMDA receptors, exhibiting IC50 values of 4.42 μM and 214.75 μM at membrane potentials of -60 mV and 40 mV, respectively, for hGluN1/hGluN2A. This compound has been shown to mitigate hippocampal damage.Fórmula:C17H20ClNOCor e Forma:SolidPeso molecular:289.8ACG548B
CAS:ACG548B inhibits AChE/BChE with IC50s of 1.78/0.496 μM; favors AChE over BChE/ChoK.Fórmula:C38H34Br2Cl2N4Cor e Forma:SolidPeso molecular:777.43AC 253
CAS:Amylin (AMY3) receptor antagonist; blocks cAMP, Ca2+, PKA, MAPK, Akt, and cFOS activity; prevents Aβ-induced neuronal death. Cyclic AC 253 variant exists.Fórmula:C122H196N40O39Pureza:98%Cor e Forma:SolidPeso molecular:2847.11PZ-1922
PZ-1922 (Compound 16), able to cross the blood-brain barrier, is a dual antagonist for 5-HT6R and 5-HT3R with K i values of 17 nM and 0.45 nM, respectively.Pureza:98%Cor e Forma:Odour SolidEB-42486
CAS:EB-42486 is an effective and highly selective inhibitor of G2019S-LRRK2 with an IC50 < 0.2 nM.Fórmula:C22H22N8OPureza:99.53%Cor e Forma:SolidPeso molecular:414.46Ref: TM-T39972
1mg70,00€2mg93,00€5mg156,00€10mg226,00€25mg409,00€50mg610,00€100mg867,00€200mg1.159,00€1mL*10mM (DMSO)170,00€Lu AF27139
CAS:Lu AF27139: P2X7 receptor antagonist; IC50: 12 nM (human), 2.4 nM (rat); Ki: 22 (mouse), 54 (human), 13 nM (rat); for CNS research.Fórmula:C21H19ClF3N5O2SPureza:99.96%Cor e Forma:SolidPeso molecular:497.92Ref: TM-T9786
1mg87,00€5mg210,00€10mg338,00€25mg562,00€50mg817,00€100mg1.103,00€1mL*10mM (DMSO)233,00€IHC3
IHC3 is a competitive and reversible monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.672 μM, which targets Cys172 within the enzyme's active site.Fórmula:C17H12FN3OPureza:98%Cor e Forma:SolidPeso molecular:293.3Desfesoterodine
CAS:<p>Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.</p>Fórmula:C22H31NO2Pureza:99.77%Cor e Forma:SolidPeso molecular:341.49Litoxetine HCl
Litoxetine HCl, an SSRI and 5-HT antagonist, treats urinary incontinence and relaxes rat oesophageal muscles without antimuscarinic effects.Fórmula:C16H20ClNOPureza:98.97% - 99.9%Cor e Forma:SoildPeso molecular:277.79Ref: TM-T67956L
1mg97,00€5mg217,00€10mg325,00€25mg557,00€50mg797,00€100mg1.103,00€1mL*10mM (DMSO)208,00€(±)-LY367385
CAS:(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.Fórmula:C10H11NO4Cor e Forma:SolidPeso molecular:209.201GSK-3β inhibitor 27
GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.Fórmula:C16H17ClN4O2Cor e Forma:SolidPeso molecular:332.79MAOA-IN-1
MAOA-IN-1 (compound 15) is an orally-active inhibitor of monoamine oxidase A (MAOA) that exhibits cytotoxic effects on prostate cancer cells.Fórmula:C13H16Cl2N2O2Pureza:98%Cor e Forma:SolidPeso molecular:303.18(-)-Coclaurine hydrochloride
CAS:(-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum.Fórmula:C17H20ClNO3Pureza:99.07%Cor e Forma:SoildPeso molecular:321.8Ref: TM-TN1519L
1mg115,00€5mg249,00€10mg369,00€25mg562,00€50mg787,00€100mg1.054,00€200mg1.406,00€1mL*10mM (DMSO)249,00€5-MeO-pyr-T
CAS:5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.Fórmula:C15H20N2OCor e Forma:SolidPeso molecular:244.33ALEPH hydrochloride
CAS:ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.Fórmula:C12H20ClNO2SCor e Forma:SolidPeso molecular:277.81Small Cardioactive Peptide B (SCPB)
CAS:SCPB: neurally active peptide, boosts adenylate cyclase in heart/gills, EC50s: 0.1 μM (heart), 1.0 μM (gills).Fórmula:C52H80N14O11S2Pureza:98%Cor e Forma:SolidPeso molecular:1141.41ECPLA
CAS:ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.Fórmula:C21H25N3OCor e Forma:SolidPeso molecular:335.44Ethylpropyltryptamine
CAS:Ethylpropyltryptamine (EPT) is an orally active novel psychoactive substance. It is predicted to act as a partial agonist of the 5-HT2A receptor.Fórmula:C15H22N2Cor e Forma:SolidPeso molecular:230.354-Hydroxy MET
CAS:4-Hydroxy MET (4-HO-MET) is a tryptamine-based new psychoactive substance (NPS), structurally similar to the endogenous neurotransmitter serotonin. It has hallucinogenic properties that affect mood, movement, and cognitive functions.Fórmula:C13H18N2OCor e Forma:SolidPeso molecular:218.3Perlapine
CAS:Perlapine is an effective and selective HM3DQ DREADD agonist (EC50 = 2.8 nM).Fórmula:C19H21N3Cor e Forma:SolidPeso molecular:291.39nAChR agonist CMPI hydrochloride
CAS:CMPI hydrochloride: Potent α4:α4 nAChR PAM; EC50 0.26 μM for (α4)3(β2)2 response to ACh; may aid nicotine dependence, neuropsychiatric research.Fórmula:C18H20Cl2N4OCor e Forma:SolidPeso molecular:379.29γ-Secretase modulator 10
CAS:γ-Secretase modulator 10 is a novel γ-secretase modulator.Fórmula:C25H23F3N4O2Cor e Forma:SolidPeso molecular:468.484-Chloromethamphetamine hydrochloride
CAS:4-Chloromethamphetamine hydrochloride is a novel psychoactive substance belonging to the amphetamine class.Fórmula:C10H15Cl2NCor e Forma:SolidPeso molecular:220.144-fluoro MBZP
CAS:4-fluoro MBZP is a novel psychoactive substance in the phenylpiperazine class, utilized for studies on the 5-HT2 receptors in the central nervous system.Fórmula:C12H17FN2Cor e Forma:SolidPeso molecular:208.28
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