Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.024 produtos)
- ACK(1 produtos)
- AChR(624 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.029 produtos)
- BACE(36 produtos)
- Beta Amilóide(224 produtos)
- CaMK(73 produtos)
- COX(600 produtos)
- Receptor de Dopamina(443 produtos)
- Receptor GABA(365 produtos)
- Gama-secretase(62 produtos)
- GluR(263 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(42 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(42 produtos)
- Receptor opioide(326 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5559 produtos de "Neurociência"
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Femoxetine
CAS:Femoxetine: antidepressant, enhances morphine, inhibits MAO-A/B, boosts mice's exercise capacity.Fórmula:C20H25NO2Pureza:99.1% - 99.35%Cor e Forma:SolidPeso molecular:311.42FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)
FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium) is a FITC-labeled amyloid beta monomer, Alzheimer’s research, drug screening, and biomolecular studies.Fórmula:C227H330N58O66S2Cor e Forma:SolidPeso molecular:4991.53β-Amyloid (1-16)
CAS:β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid.Fórmula:C84H119N27O28Pureza:98%Cor e Forma:SolidPeso molecular:1955.04Inaperisone
CAS:Inaperisone: a novel muscle relaxant that indirectly inhibits voiding reflex via brainstem GABAB receptors.Fórmula:C16H23NOPureza:98.83%Cor e Forma:SolidPeso molecular:245.36GRGDSPK acetate
CAS:GRGDSPK acetate shows inhibitory activity against integrin-fibronectin binding and can be used in research on integrins in bone formation and resorption.Fórmula:C30H53N11O13Pureza:97.9%Cor e Forma:SoildPeso molecular:775.81Zanapezil free base
CAS:Zanapezil (TAK-147): potent, selective AChE inhibitor; reversible; IC50=51.2 nM; moderate M1/M2 inhibition; AD research potential.Fórmula:C25H32N2OCor e Forma:SolidPeso molecular:376.544δ-secretase inhibitor 11
CAS:<p>δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.</p>Fórmula:C10H12N4O2Pureza:99.84%Cor e Forma:SolidPeso molecular:220.23sabcomeline
CAS:Sabcomeline: potent, selective M1 agonist; boosts cognition; for Alzheimer's study.Fórmula:C10H15N3OCor e Forma:SolidPeso molecular:193.25MLCK Peptide
CAS:MLCK Peptide, a high-affinity (pM), fully reversible CaM-binding peptide, is derived from smooth muscle myosin light-chain kinase [1].Fórmula:C91H156N36O20Cor e Forma:SolidPeso molecular:2074.44M1/M4 muscarinic agonist 2
Compound 40 is a selective M1/M4 muscarinic antagonist with an IC50 of 19 nM for M1 receptors and 42 nM for M4 receptors [1].Cor e Forma:Odour SolidEncecalinol
CAS:Encecalinol, a compound isolated from the aerial parts of Ageratina grandifolia, acts as a potent inhibitor of calmodulin [1].Fórmula:C14H18O3Cor e Forma:SolidPeso molecular:234.29γ-Secretase Modulators
CAS:gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β.Fórmula:C26H24F3N3O3Pureza:98%Cor e Forma:SolidPeso molecular:483.48AL 34662
CAS:AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also aFórmula:C10H13N3OPureza:99.97%Cor e Forma:SolidPeso molecular:191.23BChE-IN-35
BChE-IN-35 (Azo-9) is an inhibitor of BChE. This compound exhibits dynamic cis/trans conformational changes, with the cis isomer preferentially binding to BChE. Additionally, BChE-IN-35 can be utilized in research on Alzheimer's disease (AD).Fórmula:C35H39N5O2Cor e Forma:SolidPeso molecular:561.72Antipsychotic agent-2
Compound 11: potent antipsychotic, binds 5-HT1A/2A/2C, D2, H1 receptors; K is 56.6-1140 nM, BBB permeable.Fórmula:C22H26FN5OCor e Forma:SolidPeso molecular:395.47Amyloid β-Protein (1-24)
CAS:Amyloid β-Protein (1-24) is a peptide identified through peptide screening. This tool predominantly employs immunoassays to gather and analyze active peptides. Peptide screening is utilized in studies involving protein interactions, functional analysis, and epitope screening, particularly relevant in the research and development of active molecules.Fórmula:C130H183N35O40Peso molecular:2876.05(S)-Vamicamide
CAS:(S)-Vamicamide is an anti-anticholinergic compound.Fórmula:C18H23N3OPureza:99.48% - 99.65%Cor e Forma:SoildPeso molecular:297.39KRP-199 sodium
KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.Fórmula:C22H12F3N5Na2O7Pureza:97.27%Cor e Forma:SoildPeso molecular:561.33CAY10787
CAS:CAY10787, an oxysterol, inhibits GABAA receptors (IC50s: 1-1.5μM) and lessens GABA responses in mouse DRG neurons.Fórmula:C27H42OCor e Forma:SolidPeso molecular:382.632mGluR3 modulator-1
CAS:1-ethyl-3-morpholin-4-yl tetrahydroisoquinoline: mGluR3 modulator, potential for Parkinson's.Fórmula:C16H21N3OPureza:98.99%Cor e Forma:SolidPeso molecular:271.36Aβ1-14-εK-KKK-MvF5 Th
<p>Aβ1-14-εK-KKK-MvF5 Th (UB311 immunogen I) is a biologically active peptide and one of the Aβ1–14 targeting peptides (B-cell epitope) used in UB-311.</p>Fórmula:C199H318N56O55Peso molecular:4372.38081Nipecotic acid
CAS:<p>Compound PDK0243, with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0243 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C6H11NO2Cor e Forma:Off-White To Pale Yellow-Beige PowderPeso molecular:129.16β-Amyloid (25-35) acetate
β-Amyloid (25-35) acetate is the Aβ(25-35) fragment of amyloid beta peptide, neurotoxicity, construct Alzheimer's disease cell and animal models.Pureza:98.26%LY3027788 hydrochloride
CAS:LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.Fórmula:C25H32ClF2NO11SCor e Forma:SolidPeso molecular:628.03Tiflucarbine
CAS:Tiflucarbine is a potential non-selective 5-HT agonist with antidepressant activity.Tiflucarbine dose-dependently increased the specific activity of solubleFórmula:C16H17FN2SPureza:97.71%Cor e Forma:SolidPeso molecular:288.38PSEN1-IN-2
PSEN1-IN-2 (Compound 13K) is a potent inhibitor of both PSEN1-APH1A and PSEN1-APH1B complexes, exhibiting IC50 values of 6.9 nM and 2.4 nM, respectively.Fórmula:C20H18ClFN2O3SCor e Forma:SolidPeso molecular:420.88γ-Acetylenic GABA hydrochloride
CAS:γ-Acetylenic GABA hydrochloride is a GABA transaminase inhibitor.Fórmula:C6H10ClNO2Pureza:97.83% - 99.44%Cor e Forma:SolidPeso molecular:163.6LP 12 hydrochloride
CAS:LP 12 hydrochloride is a selective 5-HT7 receptor agonist (Ki=0.13 nM).Fórmula:C32H40ClN3OCor e Forma:SolidPeso molecular:518.14Imipramine N-oxide
CAS:Imipramine N-oxide is a tricyclic antidepressant (TCA) and imipramine analogue used to treat depression.Fórmula:C19H24N2OPureza:99.80%Cor e Forma:SolidPeso molecular:296.41Ref: TM-T74205
1mg75,00€5mg166,00€10mg254,00€25mg432,00€50mg596,00€100mg838,00€1mL*10mM (DMSO)171,00€Lisuride maleate
CAS:Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.Fórmula:C24H30N4O5Pureza:99.85%Cor e Forma:SolidPeso molecular:454.52Ref: TM-T8775
1mg204,00€5mg627,00€10mg898,00€25mg1.346,00€50mg1.745,00€100mg2.382,00€1mL*10mM (DMSO)627,00€GSK-3β inhibitor 27
GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.Fórmula:C16H17ClN4O2Cor e Forma:SolidPeso molecular:332.79CDD0102 HCl
CAS:CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.Fórmula:C8H13ClN4OPureza:99.7%Cor e Forma:SoildPeso molecular:216.67(S)-AMPA HCl
(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.Fórmula:C7H11ClN2O4Pureza:99.18%Cor e Forma:SolidPeso molecular:222.63GABAA receptor modulator-3
GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.Fórmula:C18H22O2Cor e Forma:SolidPeso molecular:270.37ANQ-9040
CAS:ANQ-9040 is a nondepolarizing neuromuscular relaxant of the steroid class.Fórmula:C36H58N2O5SCor e Forma:SolidPeso molecular:630.92SB 699551
CAS:SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.Fórmula:C34H45N3OPureza:99.83%Peso molecular:511.74Ref: TM-T23325L
1mg201,00€5mg497,00€10mg700,00€25mg1.094,00€50mg1.508,00€100mg1.922,00€200mg2.627,00€β-Secretase inhibitor-STA
CAS:<p>BACE-IN-1 is amyloid precursor protein beta-secretase inhibitor</p>Fórmula:C73H118N16O27Pureza:98%Cor e Forma:SolidPeso molecular:1651.81Bencycloquidium Bromide
CAS:Bencycloquidium bromide is an M3 muscarinic antagonist that reduces nasal secretion in allergic rhinitis and has high affinity for M3 receptors.Fórmula:C21H32BrNO2Cor e Forma:SolidPeso molecular:410.39AChE-IN-87
AChE-IN-87 is an AChE inhibitor with an IC50 of 0.05 μM and a Ki of 16.93 nM. It exhibits no cytotoxicity toward 3T3 cells and is suitable for Alzheimer's disease (AD) research.Fórmula:C32H39N3O12S2Cor e Forma:SolidPeso molecular:721.19752hAChE/hBuChE-IN-1
hAChE/hBuChE-IN-1 (compound C2) acts as a dual inhibitor of cholinesterases, exhibiting IC50 values of 514 nM for hAChE and 358 nM for hBuChE. It is orally active and capable of enhancing cognitive function and spatial memory.Fórmula:C30H31FN2O3Cor e Forma:SolidPeso molecular:486.577β-Amyloid (29-40)
CAS:β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical propertiesFórmula:C49H88N12O13SPureza:98%Cor e Forma:SolidPeso molecular:1085.365-HT6 inverse agonist 1
CAS:5-HT6 inverse agonist 1 (Compound 33) is an antagonist of the 5-HT6 receptor with a Ki of 23 nM and a Kb of 6.62 nM. This compound can inhibit 5-HT6R-mediated Cdk5 and mTOR signaling pathways and reduce tactile allodynia induced by spinal nerve ligation (SNL) in rat models.Fórmula:C22H22Cl2FN3O3SCor e Forma:SolidPeso molecular:498.4Methyl ganoderate A acetonide
CAS:Methyl ganoderate A from Ganoderma lucidum is a natural AChE inhibitor (IC50=18.35 μM) for Alzheimer's research.Fórmula:C34H50O7Cor e Forma:SolidPeso molecular:570.76α-Conotoxin EI
CAS:Selective antagonist of neuromuscular nicotinic receptors α1β1γδFórmula:C83H125N27O27S5Pureza:98%Cor e Forma:SolidPeso molecular:2093.372-Hydroxyalbrassitriol
CAS:2-Hydroxyalbrassitriol (Compound 6) is an AChE inhibitor with an IC 50 of 35.97 μM [1] .Fórmula:C15H26O4Cor e Forma:SolidPeso molecular:270.36Emamectin B1a
CAS:<p>Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.</p>Fórmula:C49H75NO13Cor e Forma:SolidPeso molecular:886.133Pseudocoptisine acetate
CAS:Pseudocoptisine acetate is a quaternary alkaloid isolated from the tubers of Corydalis turtschaninovii,with anti-inflammatory properties.Fórmula:C21H17NO6Pureza:98%Cor e Forma:SolidPeso molecular:379.36Fasciculic acid A
CAS:Fasciculic acid A is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.Fórmula:C36H60O8Cor e Forma:SolidPeso molecular:620.868BTMPS
CAS:BTMPS is a usage-dependent nicotinic antagonist capable of reducing acute withdrawal symptoms associated with morphine use.Fórmula:C28H52N2O4Pureza:98.1%Cor e Forma:SolidPeso molecular:480.725α-Androst-16-en-3α-ol
CAS:5α-Androst-16-en-3α-ol is a steroid pheromone that has been found in boar testes and human male axillary sweat and has diverse biological activities.1,2ItFórmula:C19H30OCor e Forma:SolidPeso molecular:274.448SQ-3
SQ-3, a quinoline analogue, prefers α-syn (Ki=39.3nM) to Aβ (Ki=230nM), and [18F]SQ3 is a lead for α-syn probes. [1]Fórmula:C21H21FN2OCor e Forma:SolidPeso molecular:336.4Br-PBTC
CAS:Br-PBTC modulates nAChRs; targets α2/β2,4 subtypes; potent with 0.1-0.6 μM EC50; binds α subunit c-tail.Fórmula:C14H15BrN2OSCor e Forma:SolidPeso molecular:339.25CPN-267
CAS:CPN-267 (compound 7b) acts as a selective agonist for the neuromediatin U receptor 1 (NMUR1), exhibiting an EC50 value of 0.25 nM. It effectively inhibits weight gain in mice, making it useful for obesity research.Fórmula:C50H66N16O8SPeso molecular:1051.23Cianopramine hydrochloride
CAS:Cianopramine hydrochloride is a bio-active chemical.Fórmula:C20H24ClN3Cor e Forma:SolidPeso molecular:341.88PD24
PD24 serves as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), with inhibitory concentrations (IC50) of 1.72 μM for humanFórmula:C24H22N2O6Cor e Forma:SolidPeso molecular:434.44(±)-LY367385
CAS:(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.Fórmula:C10H11NO4Cor e Forma:SolidPeso molecular:209.201PD07
PD07 is an orally active acetylcholinesterase (AChE) inhibitor, exhibiting an IC50 of 0.29 μM against human AChE, and demonstrates inhibition of cholinesterasesFórmula:C23H21ClN2O4Cor e Forma:SolidPeso molecular:424.886,9-Dichloro-1,2,3,4-tetrahydroacridine
CAS:6,9-Dichloro-1,2,3,4-tetrahydroacridine is a synthetic intermediate in the synthesis of tacrine-based acetylcholinesterase (AChE) inhibitors.1It is also anFórmula:C13H11Cl2NCor e Forma:SolidPeso molecular:252.139BIBD-124
CAS:BIBD-124, with an IC50 value of 9.51 nM, effectively binds to amyloid beta (Aβ) plaques.Fórmula:C19H24FN3O3Cor e Forma:SolidPeso molecular:361.41meta-Fluoxetine (hydrochloride)
CAS:meta-Fluoxetine (hydrochloride) can be used in related research in the field of life sciences. Its product number is T37474 and CAS number is 79088-29-2.Fórmula:C17H19ClF3NOCor e Forma:SolidPeso molecular:345.79Rocuronium
CAS:Rocuronium is an blocker of aminosteroid non-depolarizing neuromuscular.Fórmula:C32H53N2O4Pureza:98%Cor e Forma:SolidPeso molecular:529.77Oxotremorine
CAS:Oxotremorine acts as an agonist of mAChR, specifically activating the M1 and M3 acetylcholine receptors. In drug discrimination experiments with macaques, it exhibits effects similar to nicotine.Fórmula:C12H18N2OCor e Forma:SolidPeso molecular:206.28CZC-54252 hydrochloride
CAS:CZC-54252 hydrochloride: selective LRRK2 inhibitor; IC50 = 1.85/1.28 nM (wild-type/G2019S); neuroprotective; EC50 = 1 nM for G2019S injury.Fórmula:C22H26Cl2N6O4SPureza:98.21%Cor e Forma:SolidPeso molecular:541.45Ref: TM-T39202
5mg52,00€10mg75,00€25mg135,00€50mg215,00€100mg319,00€200mg449,00€1mL*10mM (DMSO)64,00€RuBi-Nicotine
CAS:Nicotinic receptor agonistFórmula:C40H44Cl2N8RuPureza:98%Cor e Forma:SolidPeso molecular:808.81β-Amyloid (1-34)
CAS:This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.Fórmula:C170H253N47O52Pureza:98%Cor e Forma:SolidPeso molecular:3787.2Ro 12-5637
CAS:Ro 12-5637 is a metabolite of moclobemide.Fórmula:C13H17ClN2O3Cor e Forma:SolidPeso molecular:284.74Desmethyl Mirtazapine (hydrochloride)
CAS:<p>Desmethyl mirtazapine is a metabolite of the antidepressant mirtazapine.1It is formed from mirtazapine by the cytochrome P450 (CYP) isoform CYP3A4.</p>Fórmula:C16H18ClN3Cor e Forma:SolidPeso molecular:287.79Cyclodrine
CAS:<p>Cyclodrine (Cyclopent) is a cholinergic (muscarinic, nicotinic) (mAChR and nAChR) receptor antagonist.</p>Fórmula:C19H29NO3Pureza:97.62%Cor e Forma:SoildPeso molecular:319.44Xenopus orexin B
CAS:Xenopus orexin B, a neuropeptide identified as an endogenous ligand for an orphan G-protein-coupled receptor, acts as a potent agonist of OX2R [1].Fórmula:C130H219N45O40S2Cor e Forma:SolidPeso molecular:3116.54CIA-1 (Free base)
CAS:CIA-1, a COUP-TFII inhibitor, has IC50 of 1.2-7.6 μM in prostate cancer cells; inhibits tumor growth in mouse prostate cancer.Fórmula:C17H19N3O2SPureza:99%Cor e Forma:SolidPeso molecular:329.42AChE/BChE-IN-20
AChE/BChE-IN-20 (compound 3m) serves as an inhibitor for both acetylcholinesterase (AChE, IC50=34.81 µM) and butyrylcholinesterase (BChE, IC50=20.66 µM). The affinity for the critical enzyme pockets and the favorable interaction profiles were established through molecular docking and kinetics simulation, making it relevant for the study of Alzheimer's disease.Cor e Forma:Odour SolidXL01126
XL01126 degrades LRRK2 (DC50: 14 nM G2019S, 32 nM WT), crosses the blood-brain barrier, aiding Parkinson's studies.Fórmula:C50H64ClFN10O6S2Cor e Forma:SolidPeso molecular:1019.69(S)-UFR2709 hydrochloride
CAS:(S)-UFR2709 HCl: competitive nAChR blocker, prefers α4β2 over α7, lessens anxiety & alcohol intake in rats, studies nicotine addiction.Fórmula:C13H18ClNO2Pureza:98.94%Cor e Forma:SolidPeso molecular:255.74Ref: TM-T37094
2mgA consultar5mg52,00€10mg81,00€25mg145,00€50mg212,00€100mg329,00€1mL*10mM (DMSO)55,00€FRM-024
CAS:FRM-024 is a powerful gamma secretase modulator with the ability to penetrate the central nervous system (CNS), designed specifically for the treatment ofFórmula:C22H22ClN5O2Cor e Forma:SolidPeso molecular:423.9Malaoxon
CAS:Malaoxon is used as an insecticide.Fórmula:C10H19O7PSCor e Forma:SolidPeso molecular:314.292-Methyl-1-indanone
CAS:2-Methyl-1-indanone is an acetylcholinesterase inhibitor and can be used for biochemical experiments and drug synthesis.Fórmula:C10H10OPureza:96.6%Cor e Forma:SolidPeso molecular:146.19BuChE-IN-21
BuChE-IN-21 (compound SXF3) is a potent and selective inhibitor of BuChE, demonstrating inhibitory effects on eqBuChE and hBuChE with IC50 values of 0.05 and 0.04 μM, respectively. Additionally, BuChE-IN-21 exhibits significant anti-inflammatory activity.Fórmula:C16H23NO2Cor e Forma:SolidPeso molecular:261.17288MGS0028
CAS:MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.Fórmula:C8H8FNO5Cor e Forma:SolidPeso molecular:217.154-Butyl-α-agarofuran
CAS:4-Butyl-alpha-agarofuran, a Gharu-wood derivative, is an anxiolytic, antidepressant, and aids neurological research.Fórmula:C18H30OCor e Forma:SolidPeso molecular:262.43AChE-IN-70
AChE-IN-70 (compound 4) is an acetylcholinesterase inhibitor. It exhibits larvicidal activity against mosquito larvae (Culex pipiens L.), making it useful for mosquito control research.Cor e Forma:Odour SolidSLAFVDVLN
SLAFVDVLN is a peptide molecule that functions as a BACE-1 inhibitor, exhibiting a Ki value of 94 nM. Additionally, SLAFVDVLN is capable of reducing the production of Aβ42.Fórmula:C45H72N10O14Cor e Forma:SolidPeso molecular:977.115-methoxy-α-Ethyltryptamine
CAS:<p>5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects. </p>Fórmula:C13H18N2OPureza:98.25%Cor e Forma:SolidPeso molecular:218.295-HT6R antagonist 6
5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.Fórmula:C24H26N4O2SCor e Forma:SolidPeso molecular:434.55AC 253
CAS:Amylin (AMY3) receptor antagonist; blocks cAMP, Ca2+, PKA, MAPK, Akt, and cFOS activity; prevents Aβ-induced neuronal death. Cyclic AC 253 variant exists.Fórmula:C122H196N40O39Pureza:98%Cor e Forma:SolidPeso molecular:2847.11GABAA receptor modulator-4
GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.Fórmula:C15H17BrO4SCor e Forma:SolidPeso molecular:373.26LY86057
CAS:LY86057 is a bioactive chemical.Fórmula:C20H26N2O3Cor e Forma:SolidPeso molecular:342.439Atagabalin
CAS:Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.Fórmula:C10H19NO2Cor e Forma:SolidPeso molecular:185.26RA306
RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.Cor e Forma:Odour SolidOXA(17-33)
CAS:Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.Fórmula:C79H125N23O22Pureza:98%Cor e Forma:SolidPeso molecular:1749Epiboxidine hydrochloride
CAS:Epiboxidine HCl: potent α4β2 nAChR agonist; Ki 0.46 nM (rat), 1.2 nM (human); Epibatidine analog.Fórmula:C10H15ClN2OCor e Forma:SolidPeso molecular:214.69(-)-Coclaurine hydrochloride
CAS:(-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum.Fórmula:C17H20ClNO3Pureza:99.07%Cor e Forma:SoildPeso molecular:321.8Ref: TM-TN1519L
1mg115,00€5mg249,00€10mg369,00€25mg562,00€50mg787,00€100mg1.054,00€200mg1.406,00€1mL*10mM (DMSO)249,00€Imagabalin
CAS:Imagabalin is an active compound used in the study of neurological diseases.Fórmula:C9H19NO2Cor e Forma:SolidPeso molecular:173.25α5-GABAA receptor modulator 1
α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.Fórmula:C21H20FN3O4Cor e Forma:SolidPeso molecular:397.4Atracurium
CAS:Atracurium (BW-33A) is a competitive AChR antagonist and non-depolarizing muscle relaxant that may cause bronchoconstriction.Fórmula:C53H72N2O122Cor e Forma:SolidPeso molecular:929.14nAChR agonist CMPI hydrochloride
CAS:CMPI hydrochloride: Potent α4:α4 nAChR PAM; EC50 0.26 μM for (α4)3(β2)2 response to ACh; may aid nicotine dependence, neuropsychiatric research.Fórmula:C18H20Cl2N4OCor e Forma:SolidPeso molecular:379.29γ-Secretase modulator 10
CAS:γ-Secretase modulator 10 is a novel γ-secretase modulator.Fórmula:C25H23F3N4O2Cor e Forma:SolidPeso molecular:468.48NF023 hexasodium
CAS:NF023 hexasodium is a selective and competitive P2X1 receptor antagonist, with IC50 values of 0.21 μM, 28.9 μM, > 50 μM and > 100 μM for human P2X1, P2X3, P2X2Fórmula:C35H26N4Na6O21S6Pureza:98%Cor e Forma:SolidPeso molecular:1168.92Multitarget AD inhibitor-1
CAS:Multitarget AD inhibitor-1: reversible, selective BuChE blocker, inhibits β-secretase and amyloid/tau aggregation, promising for Alzheimer's research.Fórmula:C29H38N2OCor e Forma:SolidPeso molecular:430.636
