Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(647 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.028 produtos)
- BACE(37 produtos)
- Beta Amilóide(231 produtos)
- CaMK(73 produtos)
- COX(602 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(373 produtos)
- Gama-secretase(62 produtos)
- GluR(265 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(42 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(41 produtos)
- Receptor opioide(327 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5638 produtos de "Neurociência"
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RWJ-51204
CAS:RWJ-51204: potent adenosine A2A blocker, GABA(A) partial agonist (IC50: 0.2-2 nM), neuroprotective, may treat Parkinson's.
Fórmula:C21H19F2N3O3Pureza:99.57% - 99.95%Cor e Forma:SolidPeso molecular:399.39Ref: TM-T16811
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€PF-03635659
CAS:PF-03635659: potent M3 antagonist, Ki=0.2 nM, long half-life, potential COPD treatment.Fórmula:C28H32N2O3Pureza:98.39% - 99.85%Cor e Forma:SolidPeso molecular:444.57Ref: TM-T33941
1mg216,00€5mg532,00€1mL*10mM (DMSO)605,00€10mg758,00€25mg1.153,00€50mg1.558,00€100mg2.097,00€500mg4.204,00€MM 77 dihydrochloride
CAS:MM 77 dihydrochloride is an effecitve 5-HT1A receptor postsynaptic antagonist with anxiolytic-like activity.Fórmula:C19H29Cl2N3O3Pureza:99.91%Cor e Forma:SolidPeso molecular:418.36Ref: TM-T23007
1mg86,00€5mg157,00€10mg215,00€1mL*10mM (DMSO)281,00€25mg472,00€50mg687,00€100mg938,00€500mg1.882,00€PNU-282987 free base
CAS:PNU-282987 is an α7 nAChR agonist (EC50=154 nM) and a 5-HT3 antagonist (IC50=4541 nM) for nervous system research.
Fórmula:C14H17ClN2OPureza:99.64%Cor e Forma:SolidPeso molecular:264.75Xanomeline
CAS:Xanomeline: orally active, M1/M4 selective activator for neurological disorders; promising in trials, crosses blood-brain barrier, liver metabolized.Fórmula:C14H23N3OSPureza:99.61%Cor e Forma:SolidPeso molecular:281.42Aceclidine
CAS:Aceclidine (1-azabicyclo[2.2.2]octan-3-yl acetate) is a modulator of M3 mAChR and can be used in studies about treating glaucoma by reducing intraocularFórmula:C9H15NO2Pureza:>99.99%Cor e Forma:SolidPeso molecular:169.22Xanomeline oxalate
CAS:Xanomeline oxalate (LY246708), a potent SMRA, boosts phosphoinositide hydrolysis; key for Alzheimer's research.Fórmula:C16H25N3O5SPureza:99.1%Cor e Forma:SolidPeso molecular:371.45Ref: TM-T13353
5mg35,00€1mL*10mM (DMSO)39,00€10mg55,00€25mg100,00€50mg159,00€100mg245,00€200mg353,00€Valiglurax
CAS:Valiglurax (VU2957), potent mGlu4 PAM, crosses blood-brain barrier, orally available; promising for Parkinson's treatment.Fórmula:C16H10F3N5Pureza:98.29%Cor e Forma:SolidPeso molecular:329.28E6801
CAS:E6801: selective 5-HT6 agonist for research in dementia, Parkinson's, depression, obesity, epilepsy, anxiety, etc.Fórmula:C17H18ClN5O2S2Pureza:96.32% - 97.24%Cor e Forma:SolidPeso molecular:423.94SB228357
CAS:SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.Fórmula:C22H17F4N3O2Pureza:99.82%Cor e Forma:SolidPeso molecular:431.38NNC 05-2090 hydrochloride
CAS:NNC 05-2090 HCl: BGT-1 inhibitor, IC50 = 10.6 μM, potential for epilepsy, neurological research.Fórmula:C27H31ClN2O2Pureza:99.11%Cor e Forma:SolidPeso molecular:451Oxotremorine M iodide
CAS:Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.Fórmula:C11H19IN2OPureza:99.57%Cor e Forma:SolidPeso molecular:322.19RS 67333 hydrochloride
CAS:RS 67333 hydrochloride is a selective 5-HT4R partial agonist (pKi=8.7) with neuroprotective properties for Alzheimer's research.Fórmula:C19H30Cl2N2O2Pureza:98.78%Cor e Forma:SolidPeso molecular:389.36CT-179
CAS:CT-179 is a potent and selective inhibitor of OLIG2, reduces tumor cell proliferation and induces apoptosis, fpr medulloblastoma and glioblastoma.Fórmula:C17H22Cl2N6OPureza:98.67%Cor e Forma:SolidPeso molecular:397.3ASM-024
CAS:ASM-024, a synthetic piperazine, activates nicotinic and β2-adrenergic receptors for potential asthma and bronchitis treatment with anti-inflammatory effects.Fórmula:C15H25N2Pureza:99.74%Cor e Forma:SolidPeso molecular:233.378-OH-Dpat
CAS:8-OH-Dpat (8-Hydroxy-DPAT) is a serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.Fórmula:C16H25NOPureza:98%Cor e Forma:SolidPeso molecular:247.38BL-1020 Mesylate
CAS:BL-1020 Mesylate (CYP-1020 Mesylate) is a GABA A receptor agonist and D2 antagonist used in studies of neurodegeneration.Fórmula:C28H45ClN4O11S4Pureza:>99.99%Cor e Forma:SolidPeso molecular:777.39CPCCOEt
CAS:CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of mGluR1bFórmula:C13H13NO4Pureza:99.91%Cor e Forma:SolidPeso molecular:247.25Pimethixene maleate
CAS:Pimethixene maleate (Pimetixene maleate) is a 5-HT2B receptor antagonist with sedative activity that can be used to study dry cough in children.Fórmula:C23H23NO4SPureza:99.55%Cor e Forma:SolidPeso molecular:409.5amyloid P-IN-1
CAS:amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer's disease, amyloidosis, osteoarthritis, andFórmula:C30H44N2O14Pureza:99.76%Cor e Forma:SolidPeso molecular:656.68Desformylflustrabromine hydrochloride
CAS:Desformylflustrabromine hydrochloride (dFBr hydrochloride) is a selective agonist of nicotinic acetylcholine receptor (nAChR) in α4β2 neurons, with pEC50 of 6.Fórmula:C17H12INO5Pureza:99.79%Cor e Forma:SolidPeso molecular:437.19Ref: TM-T11004
2mg34,00€5mg50,00€1mL*10mM (DMSO)57,00€10mg80,00€25mg145,00€50mg225,00€100mg353,00€200mg550,00€NNC 05-711
CAS:NNC 05-711 (NO-711 hydrochloride) is a potent and selective inhibitor of GAT-1 (GABA transporter 1), exerting anticonvulsant and analgesic effects.Fórmula:C21H23ClN2O3Pureza:99.92%Cor e Forma:SolidPeso molecular:386.87ML 10302 hydrochloride
CAS:ML 10302 hydrochloride is a specific agonist 5-HT4 and binds 5-HT receptors with Kis of 1.07 nM and 782 nM for 5-HT4 and 5-HT3.Fórmula:C15H22Cl2N2O3Pureza:99.99%Cor e Forma:SolidPeso molecular:349.25MNI 137
CAS:MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat.Fórmula:C15H9BrN4OPureza:97.49%Cor e Forma:SolidPeso molecular:341.165HT6-ligand-1
CAS:5HT6-ligand-1 is an orally active ligand of 5-HT6 receptor (Ki = 1.43 nM).Fórmula:C20H22BrN3O2SPureza:99.24% - 99.93%Cor e Forma:SolidPeso molecular:448.38NKY80
CAS:NKY80 regulates the adenylyl cyclase catalytic activity in heart and lung tissues.Fórmula:C12H11N3O2Pureza:99.88%Cor e Forma:SolidPeso molecular:229.23Ref: TM-T16333
2mg44,00€5mg64,00€10mg90,00€1mL*10mM (DMSO)100,00€25mg177,00€50mg309,00€100mg470,00€200mg677,00€McN-A 343
CAS:McN-A 343: Selective M1 muscarinic agonist; reduces inflammation in colitis models.Fórmula:C14H18Cl2N2O2Pureza:99.65%Cor e Forma:SolidPeso molecular:317.21GSK233705
CAS:GSK233705, a muscarinic antagonist, is used to prevent/treat COPD and asthma.Fórmula:C24H29BrN2Pureza:99.87% - 99.98%Cor e Forma:SolidPeso molecular:425.4Faxeladol
CAS:Faxeladol: adrenergic, serotonin inhibitor & opioid agonist for neurological studies.Fórmula:C15H23NOPureza:98.77% - 99.67%Cor e Forma:SolidPeso molecular:233.35Agomelatine hydrochloride
CAS:Agomelatine HCl is a MT1/MT2 receptor agonist (Ki: 0.1-0.27 nM) and a 5-HT2C antagonist (pKi: 6.2-6.4).Fórmula:C15H18ClNO2Pureza:99.57%Cor e Forma:SolidPeso molecular:279.76ADR-851 free base
CAS:ADR-851 free base is an antagonist of the HT3 receptor.Fórmula:C14H18ClN3O2Pureza:97.88% - 98.39%Cor e Forma:SolidPeso molecular:295.77Dipraglurant
CAS:Dipraglurant: a blood-brain permeable mGluR5 NAM, orally active, selective, IC50 = 21 nM, treats PD-LID.Fórmula:C16H12FN3Pureza:98.7%Cor e Forma:SolidPeso molecular:265.29Ref: TM-T15134
1mg92,00€5mg215,00€1mL*10mM (DMSO)260,00€10mg313,00€25mg685,00€50mg1.009,00€100mg1.341,00€Ezeprogind disulfate
CAS:Ezeprogind disulfate: neurotrophic inducer targeting neurodegeneration causes like Abeta, tau; for neurological disorder research.Fórmula:C25H48N6O8S2Pureza:99.72%Cor e Forma:SolidPeso molecular:624.81Litoxetine
CAS:Litoxetine: a selective 5-HT inhibitor & 5-HT3 antagonist, used as an antidepressant with antiemetic effects, Ki=85 nM.Fórmula:C16H19NOPureza:99.68%Cor e Forma:SolidPeso molecular:241.33Ref: TM-T67956
1mg92,00€1mL*10mM (DMSO)178,00€5mg207,00€10mg309,00€25mg527,00€50mg755,00€100mg1.044,00€500mg2.088,00€Saripidem
CAS:Saripidem (SL-85.0274) is a compound with anxiolytic activity.Fórmula:C19H20ClN3OPureza:98.42%Cor e Forma:SolidPeso molecular:341.83Iperoxo
CAS:Iperoxo (Iperoxo iodide) is an agonist of Muscarinic AChR and can be used to probe activation-related conformational transitions of muscarinic receptors.Fórmula:C10H17IN2O2Pureza:99.81%Cor e Forma:SolidPeso molecular:324.16Ref: TM-T25538
1mg50,00€5mg106,00€1mL*10mM (DMSO)117,00€10mg168,00€25mg339,00€50mg512,00€100mg748,00€200mg1.026,00€ALX-1393
CAS:ALX-1393 is a selective GlyT2 inhibitor that effectively reduces neuronal action potential activity in a concentration-dependent manner and inhibits theFórmula:C23H22FNO4Pureza:99.83%Cor e Forma:SolidPeso molecular:395.42Ref: TM-T14198
1mg1.243,00€5mg2.520,00€1mL*10mM (DMSO)2.592,00€10mg3.402,00€25mg5.059,00€50mg6.832,00€100mg8.883,00€BPDBA
CAS:BPDBA is an effective, selective, and non-competitive inhibitor of the betaine/GABA transporter (BGT-1), displaying inhibitory activity against human BGT-1 andFórmula:C19H20Cl2N2OPureza:99.43% - 99.95%Cor e Forma:SolidPeso molecular:363.285-HT1A modulator 1
CAS:5-HT1A modulator 1 displays very high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor (IC50s = 2 nM, 10 nM, and 40 nM).Fórmula:C21H25N3O2SPureza:99.68%Cor e Forma:SolidPeso molecular:383.51Lesopitron
CAS:Lesopitron: anxiolytic, 5-HT1A agonist, treats rodent anxiety, counters benzodiazepine withdrawal, low toxicity, no alcohol/barbiturate interaction.Fórmula:C15H21ClN6Pureza:99.33% - 99.46%Cor e Forma:SolidPeso molecular:320.82Ref: TM-T25672
1mg133,00€1mL*10mM (DMSO)323,00€5mg324,00€10mg477,00€25mg773,00€50mg1.063,00€100mg1.431,00€500mg2.872,00€H-9 dihydrochloride
CAS:H-9 dihydrochloride: Strong PKA inhibitor, curbs 5-HT response and EGF signaling, affects pharyngeal function.Fórmula:C11H15Cl2N3O2SPureza:97.3%Cor e Forma:SolidPeso molecular:324.23Lensiprazine
CAS:Lensiprazine (SLV314) is a potent dopamine D(2) receptor antagonist that acts as a serotonin reuptake inhibitor , and can be used to study bipolar disorder andFórmula:C24H27FN4O2Pureza:97.86%Cor e Forma:SolidPeso molecular:422.5Panadiplon
CAS:Panadiplon (FG 10571) is a selective gamma-aminobutyric acid receptor agonist and partial agonist of 5GABAA, a benzodiazepine receptor, used in the treatment ofFórmula:C18H17N5O2Pureza:98.30% - 98.94%Cor e Forma:SolidPeso molecular:335.36RS 42358-197
CAS:RS 42358-197 (RS 25259-007) is a competitive 5-HT3 receptor antagonist.Fórmula:C19H23ClN2OPureza:99.70%Cor e Forma:SolidPeso molecular:330.85Ref: TM-T20739
1mg158,00€1mL*10mM (DMSO)349,00€5mg351,00€10mg527,00€25mg783,00€50mg1.054,00€100mg1.414,00€200mg1.908,00€Cirsimaritin
CAS:Cirsimaritin has anti-bacterial, anti-inflammatory, anti-tumor, antioxidant effects, and protects kidneys; it weakly targets GABAA receptors.
Fórmula:C17H14O6Pureza:99.9%Cor e Forma:SolidPeso molecular:314.29Sudoxicam
CAS:Sudoxicam (4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide) is a reversible antagonist of COX with anti-inflammatory, anti-edema
Fórmula:C13H11N3O4S2Pureza:99.93%Cor e Forma:SolidPeso molecular:337.37(Z)-Thiothixene
CAS:(Z)-Thiothixene (Thiothixene) is an antagonist of serotonergic receptor.
Fórmula:C23H29N3O2S2Pureza:99.21%Cor e Forma:Yellow To Yellow With A Tan Cast PowderPeso molecular:443.63SCH-900271
CAS:SCH-900271 treats dyslipidemia by targeting nicotinic acid receptors, addressing hyperlipidaemia.Fórmula:C14H16N2O4Pureza:98.82% - 99.93%Cor e Forma:SolidPeso molecular:276.29Ref: TM-T34573
1mg112,00€1mL*10mM (DMSO)249,00€5mg261,00€10mg396,00€25mg655,00€50mg888,00€100mg1.251,00€500mg2.493,00€LY-2624803
CAS:LY-2624803 is a 5-HT2A receptor antagonist and histamine receptor inverse agonist that can be used to improve slow wave sleep.Fórmula:C22H25N3O3Pureza:99.78% - 99.97%Cor e Forma:SolidPeso molecular:379.45Tiospirone
CAS:Tiospirone (BMY 13859-1 free base) is a 5-HT2 receptor antagonist and a dopamine blocker used in the study of neurological disorders such as schizophrenia.Fórmula:C24H32N4O2SPureza:99.74%Cor e Forma:SolidPeso molecular:440.6Ref: TM-T24885
1mg123,00€5mg293,00€1mL*10mM (DMSO)354,00€10mg537,00€25mg863,00€50mg1.161,00€100mg1.558,00€Glutaminyl Cyclase Inhibitor 1
CAS:Glutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor (IC50: 0.5 μM) that can be used to study neurological disorders.Fórmula:C21H24FN3O2Pureza:99.81%Cor e Forma:SolidPeso molecular:369.435-HT6/7 antagonist 1
CAS:5-HT6/7 antagonist 1 is a dual 5-HT6/7/2A and D2 receptor antagonist for the study of dementia and Alzheimer's disease.Fórmula:C22H20FN3O3Pureza:98.78% - 99.26%Cor e Forma:SolidPeso molecular:393.41BI-1408
CAS:BI-1408 is a modulator potent of γ secretase (IC50: 0.04 μM for Aβ42).Fórmula:C22H23FN6Pureza:99.63%Cor e Forma:SolidPeso molecular:390.46Quinupramine
CAS:Quinupramine: an oral antidepressant targeting the serotonin system; penetrates CNS; doesn’t affect β-adrenergic system.Fórmula:C21H24N2Pureza:99.77%Cor e Forma:SolidPeso molecular:304.43NB001
CAS:NB001 (HTS 09836) is an inhibitor of adenyl cyclase 1 exhibiting effects on neural and non-neural pain.Fórmula:C12H20N6OPureza:99.69%Cor e Forma:Off-White To Pale Pink SolidPeso molecular:264.33Ref: TM-T16275
1mg74,00€1mL*10mM (DMSO)173,00€5mg200,00€10mg295,00€25mg497,00€50mg710,00€100mg964,00€500mg1.935,00€SPD-473 citrate
CAS:SPD-473 citrate is an inhibitior of serotonin/dopamine/norepinephrine reuptake.Fórmula:C23H31Cl2NO8SPureza:99.37%Cor e Forma:SolidPeso molecular:552.47BMY-14802 hydrochloride
CAS:BMY-14802 hydrochloride (BMS 181100 hydrochloride) is a selective antagonist of σ receptor (IC50 = 112 nM) with antipsychotic effects.Fórmula:C18H23ClF2N4OPureza:99.97%Cor e Forma:SolidPeso molecular:384.85Piromelatine
CAS:Piromelatine is an agonist of melatonin MT1/MT2 receptors, 5-HT1A and 5-HT1D, and an antagonist of 5-HT2B.Piromelatine has antinociceptive activity withFórmula:C17H16N2O4Pureza:99.83%Cor e Forma:SolidPeso molecular:312.32Ref: TM-T34081
1mg60,00€5mg130,00€1mL*10mM (DMSO)142,00€10mg178,00€25mg334,00€50mg522,00€100mg713,00€GR 46611
CAS:GR 46611 is a selective 5-HT1B and 5-HT1D receptor agonist and can be used in studies about the treatment of epilepsy.Fórmula:C23H27N3O2Pureza:99.75%Cor e Forma:SolidPeso molecular:377.48CBiPES hydrochloride
CAS:CBiPES hydrochloride (CBiPES HCl) is an orthosteric modulator of the mGlu2 receptor and is used to study neurological disorders like epilepsy.Fórmula:C21H20ClN3O2SPureza:99.66%Cor e Forma:SolidPeso molecular:413.92Tribendimidine
CAS:Tribendimidine: broad-spectrum oral anthelmintic, nAChR agonist, effective against A. lumbricoides and N. americanus.Fórmula:C28H32N6Pureza:≥98%Cor e Forma:SolidPeso molecular:452.59LRRK2-IN-7
CAS:LRRK2-IN-7: potent, selective CNS-active LRRK2 inhibitor, IC50 0.9 nM, >1000x selectivity vs kinases/channels/CYPs.Fórmula:C24H26N6OPureza:99.26%Cor e Forma:SolidPeso molecular:414.5MAO-B-IN-9
CAS:MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence.Fórmula:C18H24N2O2Pureza:99.93%Cor e Forma:SolidPeso molecular:300.4Ref: TM-T60671
2mg39,00€5mg58,00€1mL*10mM (DMSO)66,00€10mg93,00€25mg167,00€50mg260,00€100mg378,00€200mg552,00€Landipirdine
CAS:Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia.Fórmula:C18H19FN2O3SPureza:97.61% - 99.99%Cor e Forma:SolidPeso molecular:362.42ABP688
CAS:ABP688 is a non-competitive and selective mGluR5 antagonist(Ki = 1.7 nM). ABP688 can be used as a PET tracer for clinical imaging.Fórmula:C15H16N2OPureza:98.63%Cor e Forma:SolidPeso molecular:240.3NS-2710
CAS:NS-2710, a GABA receptor agonist, is used potentially for the treatment of anxiety.Fórmula:C22H20N4OPureza:99.7% - 99.82%Cor e Forma:SolidPeso molecular:356.42ELB-139
CAS:ELB-139 is a GABA A receptor agonist. ELB139 increases 5-HT in the striatum and prefrontal cortex of rats.Fórmula:C14H16ClN3OPureza:>99.99%Cor e Forma:SolidPeso molecular:277.75Zamifenacin fumarate
CAS:Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.Fórmula:C31H33NO7Pureza:99.88%Cor e Forma:SolidPeso molecular:531.6Ref: TM-T13385
2mg34,00€5mg50,00€1mL*10mM (DMSO)58,00€10mg75,00€25mg128,00€50mg200,00€100mg304,00€200mg424,00€Org-21465
CAS:Org-21465, a gamma-aminobutyric acid (GABA) receptor agonist, is used potentially for the use of anesthesia.Fórmula:C27H43NO4Pureza:98%Cor e Forma:SolidPeso molecular:445.63Zaldaride (free base)
CAS:Zaldaride (free base) is a calmodulin antagonist.Fórmula:C26H28N4O2Cor e Forma:SolidPeso molecular:428.531-Carboxycyclohexaneacetic Acid
CAS:1-Carboxycyclohexaneacetic acid may be present as a potential impurity in commercial gabapentin, an antiepileptic drug. Furthermore, it serves as a precursor for synthesizing antagonists targeting the serotonin (5-HT) receptor subtype 5-HT2A.Fórmula:C9H14O4Cor e Forma:SolidPeso molecular:186.207Abaperidone
CAS:Abaperidone is an atypical antipsychotic, antagonizes 5-HT2A (IC50=6.2 nM) and D2 receptors (IC50=17 nM), reduces hsp70 mRNA in rat brains.Fórmula:C25H25FN2O5Pureza:99.77%Cor e Forma:SolidPeso molecular:452.47RPC425 free base
CAS:RPC425 is a noncompetitive inhibitors of the Betaine-γ-Aminobutyric Acid Transporter 1 (BGT1).Fórmula:C22H27NO2S2Pureza:98%Cor e Forma:SolidPeso molecular:401.59MAO-B-IN-27
CAS:MAO-B-IN-27 (Compound 12c), a monoamine oxidase B (MAO-B) inhibitor, exhibits a potent and selective inhibitory effect on hMAO-B, with an IC50 value of 8.9 nM,Fórmula:C16H17ClF3NOPureza:98%Cor e Forma:SolidPeso molecular:331.765-HT2A receptor agonist-3
CAS:5-HT2A receptor agonist-3 represents the highest selectivity for the human 5-HT2A receptor currently identified, exhibiting a K i of 2.5 nM.Fórmula:C21H26BrNO3Pureza:98%Cor e Forma:SolidPeso molecular:420.345-HT2A&5-HT2C agonist-1
CAS:5-HT2A&5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM.Fórmula:C14H20N2OPureza:98%Cor e Forma:SolidPeso molecular:232.32BACE1-IN-10
CAS:BACE1-IN-10 is a potent inhibitor of BACE1, demonstrating sub-micromolar activity against recombinant BACE1 (rBACE1) [1].Fórmula:C33H49N5O8SPureza:98%Cor e Forma:SolidPeso molecular:675.84BMS-983970
CAS:BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.Fórmula:C26H26F4N4O3Cor e Forma:SolidPeso molecular:518.5FK-1052
CAS:FK-1052 is a serotonin 3 & 4 dual receptor antagonist.Fórmula:C18H19N3OCor e Forma:SolidPeso molecular:293.36Osemozotan Free Base
CAS:Osemozotan Free Base is a 5-HT(1A) receptor agonist.Fórmula:C19H21NO5Cor e Forma:SolidPeso molecular:343.37PZ-II-029
CAS:PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.Fórmula:C18H15N3O3Pureza:99.79%Cor e Forma:SolidPeso molecular:321.33Ref: TM-T28479
1mg50,00€5mg105,00€10mg167,00€1mL*10mM (DMSO)192,00€25mg289,00€50mg447,00€100mg685,00€500mg1.378,00€Brilaroxazine
CAS:Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.Fórmula:C22H25Cl2N3O3Pureza:99.36%Cor e Forma:SolidPeso molecular:450.36Ref: TM-T14782
1mg100,00€5mg236,00€1mL*10mM (DMSO)268,00€10mg385,00€25mg663,00€50mg954,00€100mg1.305,00€200mg1.738,00€FPTQ
CAS:FPTQ is a highly effective antagonist of mGluR 1, displaying IC50 values of 6 nM and 1.4 nM for human and mouse mGluR1 respectively [1].Fórmula:C17H12FN5Pureza:99.68% - 99.88%Cor e Forma:SolidPeso molecular:305.31Ref: TM-T5509
500mgA consultar1mg52,00€2mg70,00€5mg105,00€1mL*10mM (DMSO)110,00€10mg152,00€25mg294,00€50mg398,00€100mg527,00€(-)-Bicuculline methochloride
CAS:(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.
Fórmula:C21H20ClNO6Pureza:98%Cor e Forma:SolidPeso molecular:417.84Timepidium bromide
CAS:Timepidium bromide is an agent of anticholinergic.Fórmula:C17H22BrNOS2Pureza:98%Cor e Forma:SolidPeso molecular:400.4rTRD01
CAS:rTRD01 is a TDP-43 ligand that selectively binds to the RRM1 and RRM2 domains of TDP-43, exhibiting a dissociation constant (Kd) of 89 µM for TDP-43 102–269.Fórmula:C18H21FN4O2Pureza:99.44%Cor e Forma:SolidPeso molecular:344.38VU6007477
CAS:VU6007477 is a brain-penetrant M1 muscarinic receptor PAM (EC50 230 nM) used for research on CNS exposure and seizure-related models.Fórmula:C24H26N6O2Pureza:99.67%Cor e Forma:SolidPeso molecular:430.5VU0360172
CAS:VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).Fórmula:C18H15FN2OPureza:99.56%Cor e Forma:SolidPeso molecular:294.32VU0453595
CAS:VU0453595 is a M1 positive allosteric modulator (PAM).
Fórmula:C18H15FN4OPureza:99.91%Cor e Forma:SolidPeso molecular:322.34BACE1-IN-1
CAS:BACE1-IN-1 is a high brain penetrant BACE1 inhibitor (IC50s: 32 and 47 nM for human BACE1 and BACE2).Fórmula:C18H14F3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:389.33(2R,4R)-APDC
CAS:(2R,4R)-APDC is a selective group II metabotropic glutamate receptors (mGluRs) agonist. It has anticonvulsant and neuroprotective effects.Fórmula:C6H10N2O4Pureza:98%Cor e Forma:SolidPeso molecular:174.15LY3202626
CAS:LY3202626, an amyloid precursor protein secretase (BACE protein) inhibitor, is used for the treatment of Alzheimer's disease.Fórmula:C22H20F2N8O2SPureza:98%Cor e Forma:SolidPeso molecular:498.51C3
CAS:C3 functions as a selective inhibitor of monoamine oxidase B (MAO-B; IC50= 0.021 µM), demonstrating preference over monoamine oxidase A (MAO-A; IC50= 26.8 µM). This compound, at dosages of 0.1, 1, and 3 mg/kg, effectively counters MPTP-induced reductions in dopamine levels within the mouse brain.Fórmula:C18H19FN2O2Cor e Forma:SolidPeso molecular:314.35MAO-IN-3
CAS:MAO-IN-3 (Compound 5), a reversible and competitive monoamine oxidase (MAO) inhibitor with inhibition constants (K i) of 0.6 μM for MAO A and 0.2 μM for MAO B,Fórmula:C42H54N4O4Pureza:98%Cor e Forma:SolidPeso molecular:678.9MDL-74156
CAS:MDL-74156 is an active metabolite of dolasetron and a 5-hydroxy-tryptamine3 (5-HT3) antagonist.Fórmula:C19H22N2O3Cor e Forma:SolidPeso molecular:326.39BACE-1 inhibitor 1
CAS:BACE-1 inhibitor 1 (Compound 8a) is an effective BACE-1 inhibitor (IC50: 56 nM).Fórmula:C17H14BrF3N4O2Pureza:98%Cor e Forma:SolidPeso molecular:443.22(±)-N-desmethyl Venlafaxine hydrochloride
CAS:(±)-N-desmethyl Venlafaxine, a minor active metabolite of venlafaxine, serves as a selective norepinephrine and serotonin reuptake inhibitor (SNRI). Generated through the metabolization by the cytochrome P450 (CYP) isoform CYP3A4, it exhibits reuptake inhibition of norepinephrine and serotonin in rat synaptosome preparations, demonstrated by IC50 values of 4.7 and 1.6 µM, respectively. Clinically, it has been shown to counteract reserpine-induced hypothermia in mice, displaying efficacy at a minimum effective dose (MED) of 10 mg/kg.Fórmula:C16H26ClNO2Cor e Forma:SolidPeso molecular:299.84(R)-4-Amino-3-hydroxybutyric Acid
CAS:(R)-4-Amino-3-hydroxybutyric acid, also known as (R)-GABOB, acts as a modulator of GABA receptors, specifically binding to both GABAA and GABAB receptors and blocking GABA reuptake in rat brain synaptosomes. Additionally, it serves as a GABAC receptor agonist, triggering currents in patch-clamp assays with Xenopus oocytes that express the human receptor. In vivo studies reveal its capability to suppress electrical discharges in the amygdala in cats undergoing N-amidinobenzamide-triggered seizures, indicating its potential therapeutic application in managing seizure disorders.Fórmula:C4H9NO3Cor e Forma:SolidPeso molecular:119.12(1α,1'S,4β)-Lanabecestat
CAS:(1α,1'S,4β)-Lanabecestat is a Beta site APP Cleaving Enzymel (BACE1) inhibitor, and has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay),Fórmula:C26H28N4OCor e Forma:SolidPeso molecular:412.53Cyanopindolol fumarate
CAS:Cyanopindolol fumarate is a 5-HT receptor antagonist [1].Fórmula:C16H21N3O2C4H4O4Cor e Forma:SolidPeso molecular:345.4
