Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(647 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.027 produtos)
- BACE(37 produtos)
- Beta Amilóide(230 produtos)
- CaMK(73 produtos)
- COX(602 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(373 produtos)
- Gama-secretase(62 produtos)
- GluR(265 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(43 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(41 produtos)
- Receptor opioide(327 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5639 produtos de "Neurociência"
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ELND007
CAS:ELND007 is a Gamma secretase inhibitor.Fórmula:C19H14F4N4O2SCor e Forma:SolidPeso molecular:438.4MK-8768
CAS:MK-8768 is a potent, selective, and orally bioavailable negative allosteric modulator of the mGluR2 class, exhibiting an IC50 of 9.6 nM and characterized byFórmula:C21H22F3N5O2Cor e Forma:SolidPeso molecular:433.43SB 258719
CAS:SB 258719 is a selective antagonist of 5-HT7 receptor with pKi of 7.5.Fórmula:C18H30N2O2SPureza:99.73%Cor e Forma:SolidPeso molecular:338.51Ref: TM-T12855
2mg34,00€5mg52,00€1mL*10mM (DMSO)58,00€10mg85,00€25mg155,00€50mg240,00€100mg355,00€200mg502,00€VU 0255035
CAS:VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.
Fórmula:C18H20N6O3S2Pureza:98.09% - 98.1%Cor e Forma:SolidPeso molecular:432.52AAK1-IN-5
CAS:AAK1-IN-5: Potent, selective AAK1 inhibitor; CNS-penetrant; oral; IC50: 1.2 nM; Ki: 0.05 nM; cell IC50: 0.5 nM. Useful in neuropathic pain research.Fórmula:C19H23F4N3OCor e Forma:SolidPeso molecular:385.4(R)-4-Amino-3-hydroxybutyric Acid
CAS:(R)-4-Amino-3-hydroxybutyric acid, also known as (R)-GABOB, acts as a modulator of GABA receptors, specifically binding to both GABAA and GABAB receptors and blocking GABA reuptake in rat brain synaptosomes. Additionally, it serves as a GABAC receptor agonist, triggering currents in patch-clamp assays with Xenopus oocytes that express the human receptor. In vivo studies reveal its capability to suppress electrical discharges in the amygdala in cats undergoing N-amidinobenzamide-triggered seizures, indicating its potential therapeutic application in managing seizure disorders.Fórmula:C4H9NO3Cor e Forma:SolidPeso molecular:119.12Diproqualone
CAS:Diproqualone, analogous to methaqualone, exhibits sedative, anxiolytic, anti-inflammatory, and analgesic properties [1].Fórmula:C12H14N2O3Cor e Forma:SolidPeso molecular:234.255Pomaglumetad methionil hydrochloride
CAS:LY2140023 hydrochloride: oral methionine prodrug of LY404039, a selective mGlu2/3 agonist, studied for schizophrenia.Fórmula:C12H19ClN2O7S2Pureza:98.57%Cor e Forma:SolidPeso molecular:402.87SDZ-216525
CAS:SDZ-216525, a 5-HT1A receptor antagonist, inhibits the tracheal contractions induced both by NKA (10 nM-3 microM) and 5-HT (10 nM-10 microM) (n=4-10).Fórmula:C25H28N4O5SCor e Forma:SolidPeso molecular:496.58CGP 55845
CAS:CGP 55845: potent, selective GABAB blocker, IC50=5 nM, hinders agonist binding, reduces GABA/glutamate release.Fórmula:C18H22Cl2NO3PCor e Forma:SolidPeso molecular:402.25Velusetrag
CAS:Velusetrag(TD-5108), a potent 5-HT4 agonist, is in development for gastroparesis, constipation, and IBS.Fórmula:C25H36N4O5SCor e Forma:SolidPeso molecular:504.64RAGE/SERT-IN-1
CAS:RAGE/SERT-IN-1 is a potent, orally active inhibitor of advanced glycation end products (RAGE) and serotonin transporter (SERT), with IC50 values of 8.26 μM andFórmula:C38H41ClN4OSCor e Forma:SolidPeso molecular:637.28LY108742
CAS:LY108742 is an antagonist of 5-HT2.Fórmula:C21H28N2O3Pureza:98%Cor e Forma:SolidPeso molecular:356.46Org-21465
CAS:Org-21465, a gamma-aminobutyric acid (GABA) receptor agonist, is used potentially for the use of anesthesia.Fórmula:C27H43NO4Pureza:98%Cor e Forma:SolidPeso molecular:445.63MDL-74156
CAS:MDL-74156 is an active metabolite of dolasetron and a 5-hydroxy-tryptamine3 (5-HT3) antagonist.Fórmula:C19H22N2O3Cor e Forma:SolidPeso molecular:326.39Adipiplon
CAS:Adipiplon(NG2-73, NG273) is a novel selective gamma-aminobutyric acid (GABA) partial agonist.Fórmula:C18H18FN7Cor e Forma:SolidPeso molecular:351.38AChE-IN-19
CAS:AChE-IN-19: strong AChE blocker (IC50: 0.56 μM), hinders Aβ clumps, neuro-protective, non-toxic to SH-SY5Y, for Alzheimer's research.Fórmula:C30H33NO7Cor e Forma:SolidPeso molecular:519.59mAChR antagonist 1
CAS:Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,Fórmula:C19H22N2O2Cor e Forma:SolidPeso molecular:310.39Quinolactacin A1
CAS:Quinolactacin A1, a strong AChE inhibitor from Penicillium citrinum, aids Alzheimer's research.Fórmula:C16H18N2O2Cor e Forma:SolidPeso molecular:270.33CGP 64213
CAS:CGP 64213 is a GABAb receptor agonist.Fórmula:C26H36IN2O7PPureza:98%Cor e Forma:SolidPeso molecular:646.45(2R,4R)-APDC
CAS:(2R,4R)-APDC is a selective group II metabotropic glutamate receptors (mGluRs) agonist. It has anticonvulsant and neuroprotective effects.Fórmula:C6H10N2O4Pureza:98%Cor e Forma:SolidPeso molecular:174.15MGS-0039
CAS:MGS-0039: Group II mGluR2/3 antagonist, non-serotonergic antidepressant-like effect, AMPA involvement, regulates dopamine in NAc.Fórmula:C15H14Cl2FNO5Pureza:98%Cor e Forma:SolidPeso molecular:378.18BChE-IN-20
CAS:BChE-IN-20 (compound 7c) is a potent, selective inhibitor of BChE, demonstrating IC50 values of 105 nM for eqBChE and 2.3 nM for hBChE.Fórmula:C27H39N5O2Cor e Forma:SolidPeso molecular:465.63BACE1-IN-1
CAS:BACE1-IN-1 is a high brain penetrant BACE1 inhibitor (IC50s: 32 and 47 nM for human BACE1 and BACE2).Fórmula:C18H14F3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:389.33LY320954
CAS:LY320954 is an antagonist of 5-HT2A receptor.Fórmula:C21H26N4O3Pureza:98%Cor e Forma:SolidPeso molecular:382.46CGP36216 hydrochloride
CAS:CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].Fórmula:C5H15ClNO2PCor e Forma:SolidPeso molecular:187.6BT-GSI
BT-GSI: γ-secretase inhibitor targeting Notch, anti-myeloma & anti-resorptive for multiple myeloma/bone disease research.Fórmula:C26H46BrN5O10P2Cor e Forma:SolidPeso molecular:730.52Anti-amyloid agent-1
CAS:Anti-amyloid agent-1 is a potent compound that inhibits amyloid aggregation, offering a promising approach for research into the treatment of amyloidosis [1].Fórmula:C21H17F3N2O3Cor e Forma:SolidPeso molecular:402.37BMS-932481
CAS:BMS-932481 is a γ-secretase modulator.Fórmula:C24H24FN7OCor e Forma:SolidPeso molecular:445.49QM-FN-SO3
CAS:QM-FN-SO3 is a blood-brain barrier (BBB)-penetrable, near-infrared (NIR) probe with aggregation-induced emission (AIE) activity, specifically designed for the detection of Aβ plaques. It exhibits ultra-high signal-to-noise (S/N) ratio, binding affinity, and high-performance NIR emission, making it suitable for in vivo detection of Aβ plaques [1].Fórmula:C29H25N4NaO3S2Cor e Forma:SolidPeso molecular:564.65AAK1-IN-3
CAS:AAK1-IN-3: Brain-penetrant AAK1 inhibitor for neuropathic pain research; IC50=11 nM.Fórmula:C20H20N4Cor e Forma:SolidPeso molecular:316.4UNC9994 hydrochloride
CAS:UNC9994 hydrochloride is a selective β-arrestin-biased D2R agonist, Ki of 79 nM, that stimulates β-arrestin and modulates cAMP.Fórmula:C21H23Cl3N2OSCor e Forma:SolidPeso molecular:457.84CAY10649
CAS:1CAY10649, a thiazolinone compound, directly inhibits 5-lipoxygenase (5-LO) product formation in intact polymorphonuclear leukocytes (PMNL) with an IC50 value of 0.28 μM and in a soluble fraction of an S100 PMNL cell lysate with an IC50 value of 0.09 μM, following stimulation by calcium and arachidonic acid. This activity highlights its potential in mitigating inflammatory responses by targeting the biosynthesis of leukotrienes, substances implicated in various inflammatory processes such as neutrophil chemotaxis, increased vascular permeability, and smooth muscle contraction.Fórmula:C17H12ClNO2SCor e Forma:SolidPeso molecular:329.8Gentisein
CAS:Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7Fórmula:C13H8O5Pureza:96.89%Cor e Forma:SolidPeso molecular:244.2LY-426965
CAS:LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist.Fórmula:C28H38N2O2Cor e Forma:SolidPeso molecular:434.61VU0360172
CAS:VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).Fórmula:C18H15FN2OPureza:99.56%Cor e Forma:SolidPeso molecular:294.32GR 125487 sulfamate
CAS:GR 125487 sulfamate is a 5-HT4 receptor antagonist.Fórmula:C19H29FN4O8S2Pureza:98%Cor e Forma:SolidPeso molecular:524.58VU6012962
CAS:VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).Fórmula:C21H19F3N4O4Pureza:99.61% - 99.74%Cor e Forma:SolidPeso molecular:448.4Ref: TM-T13323
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg119,00€25mg225,00€50mg404,00€100mg592,00€L-822179
CAS:L-822179 (α5IA) is a selective inverse agonist for the Α5 subtype of GABAA receptor with higher intrinsic activity at the A5 subtype than other drugs.Fórmula:C17H14N8O2Pureza:98.5% - 99.61%Cor e Forma:SolidPeso molecular:362.35ASP8302
CAS:ASP8302 is an allosteric potentiator of the muscarinic M3 receptor. It enhances urination efficiency and reduces residual urine volume in two rat models of voiding dysfunction. ASP8302 is useful for investigating diseases associated with bladder dysfunction.Fórmula:C26H32ClN7O3S2Cor e Forma:SolidPeso molecular:590.16COR659
CAS:COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.Fórmula:C16H16ClNO3SPureza:99.75%Cor e Forma:SolidPeso molecular:337.82Ref: TM-T36520
1mg38,00€5mg86,00€1mL*10mM (DMSO)94,00€10mg123,00€25mg215,00€50mg299,00€100mg411,00€200mg560,00€Nemonapride
CAS:Nemonapride is a dopamine D2-like receptor antagonist.Fórmula:C21H26ClN3O2Pureza:98%Cor e Forma:SolidPeso molecular:387.9C3
CAS:C3 functions as a selective inhibitor of monoamine oxidase B (MAO-B; IC50= 0.021 µM), demonstrating preference over monoamine oxidase A (MAO-A; IC50= 26.8 µM). This compound, at dosages of 0.1, 1, and 3 mg/kg, effectively counters MPTP-induced reductions in dopamine levels within the mouse brain.Fórmula:C18H19FN2O2Cor e Forma:SolidPeso molecular:314.35ABT-418 hydrochloride
CAS:ABT-418 HCl enhances cognition and reduces anxiety as a selective nAChRs agonist, researched for Alzheimer's.Fórmula:C9H15ClN2OCor e Forma:SolidPeso molecular:202.68Hydroxy Varenicline
CAS:Hydroxy varenicline, a metabolite of the nicotinic acetylcholine receptor (nAChR) agonist varenicline, functions within the biochemical pathway by interacting with nAChR sites.Fórmula:C13H13N3OCor e Forma:SolidPeso molecular:227.267Lanabecestat HCl
CAS:Lanabecestat (AZD3293/LY3314814) is a potent oral BACE1 inhibitor that crosses the BBB and reduces Aβ levels.Fórmula:C26H29ClN4OCor e Forma:SolidPeso molecular:448.995QR-0217
CAS:QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40.Fórmula:C19H13NO3Cor e Forma:SolidPeso molecular:303.31Befiradol
CAS:Befiradol (NLX-112) is an agonist of 5-HT1A receptor.Fórmula:C20H22ClF2N3OCor e Forma:SolidPeso molecular:393.86SB 649915
CAS:SB 649915 is a serotonin reuptake inhibitor and 5-HT1A and 5-HT1B receptor antagonist.Fórmula:C26H29N3O3Cor e Forma:SolidPeso molecular:431.53GYKI-46903 HCl
CAS:GYKI-46903 is a noncompetitive 5-HT3 receptor antagonist.Fórmula:C17H21ClFNO2Cor e Forma:SolidPeso molecular:325.815-HT2 agonist-1
CAS:Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively.Fórmula:C19H23ClN2O2Pureza:98%Cor e Forma:SolidPeso molecular:346.855-HT3-In-1
CAS:5-HT3-In-1 (compound example 8) exhabits with 5-HT3 inhibition activity.Fórmula:C16H21ClN4O3Pureza:98%Cor e Forma:SolidPeso molecular:352.824-Chloro-L-phenylalanine
CAS:4-Chloro-L-phenalanine (L-PCPA) is an inhibitor of 5-HT biosynthesis and a non-specific antagonist of tryptophan hydroxylases (TPH1 and TPH2).Fórmula:C9H10ClNO2Pureza:99.76% - 99.96%Cor e Forma:SolidPeso molecular:199.635-HT2C agonist-3 free base
CAS:5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), exhibits antipsychotic drug-like activity and inhibits Amphetamine-Fórmula:C19H22FNO2Pureza:98%Cor e Forma:SolidPeso molecular:315.38Brasofensine
CAS:Brasofensine, a benztoalkane MA reuptake inhibitor, shows promise for Parkinson's and Alzheimer's.Fórmula:C16H20Cl2N2OCor e Forma:SolidPeso molecular:327.255-HT2 agonist-1 free base
CAS:Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM,Fórmula:C19H22N2O2Pureza:98%Cor e Forma:SolidPeso molecular:310.39BMS 433796
CAS:BMS 433796 is a γ-secretase inhibitor that demonstrates Aβ-lowering activity within a transgenic mouse model of Alzheimer's disease.Fórmula:C21H20F2N4O4Pureza:99.17%Cor e Forma:SolidPeso molecular:430.45-HT2C agonist-3
CAS:5-HT2C agonist-3 ((+)-19), a selective 5-HT2C agonist (EC 50: 24 nM, Ki: 78 nM), exhibits antipsychotic-like activity by blocking amphetamine-inducedFórmula:C19H23ClFNO2Pureza:98%Cor e Forma:SolidPeso molecular:351.84mGluR5 antagonist-1
CAS:mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1].Fórmula:C23H18N4O2Cor e Forma:SolidPeso molecular:382.41MAO-B-IN-1
CAS:MAO-B-IN-1 is a monoamine oxidase B inhibitor and can be used for the research of neurological diseases.Fórmula:C16H14F3N3O2SPureza:98%Cor e Forma:SolidPeso molecular:369.36(S)-Bexicaserin
CAS:(S)-Bexcaserin (compound 2) serves as a 5-HT2C receptor agonist, presenting research possibilities in obesity and psychiatric disorders [1].Fórmula:C15H19F2N3OPureza:98%Cor e Forma:SolidPeso molecular:295.33Mesembrine
CAS:Mesembrine is an alkaloid, a 5-HT transporter inhibitor (K i 1.4 nM), and inhibits PDE4B (IC50 7.8 μM).Fórmula:C17H23NO3Cor e Forma:SolidPeso molecular:289.37PZ-1190
CAS:PZ-1190, a multitarget ligand for serotonin and dopamine receptors, exhibits potential antipsychotic activity in rodents [1].Fórmula:C27H30N4O2S2Pureza:98%Cor e Forma:SolidPeso molecular:506.68GABAA receptor agent 2 TFA
CAS:Potent GABAA antagonist; IC50: 24 nM (α1β2γ2), Ki: 28 nM (rat); inactive on human GABA transporters.Fórmula:C22H22F3N3O3Cor e Forma:SolidPeso molecular:433.42Brasofensine sulfate
CAS:Brasofensine sulfate is a dopamine reuptake inhibitor.Fórmula:C16H22Cl2N2O5SCor e Forma:SolidPeso molecular:425.33SCS
CAS:SCS is a GABAA receptor antagonist.Fórmula:C14H12N2O3Pureza:99.73%Cor e Forma:SolidPeso molecular:256.26NAS181
CAS:rat 5-HT1B receptor antagonistFórmula:C21H34N2O10S2Pureza:98%Cor e Forma:SolidPeso molecular:538.63MAO-B-IN-19
CAS:MAO-B-IN-19, a selective MAO-B inhibitor, exhibits neuroprotective and anti-inflammatory properties and demonstrates an IC50 value of 0.67 μM [1].Fórmula:C15H11FO2Pureza:98%Cor e Forma:SolidPeso molecular:242.25Timepidium bromide
CAS:Timepidium bromide is an agent of anticholinergic.Fórmula:C17H22BrNOS2Pureza:98%Cor e Forma:SolidPeso molecular:400.4(-)-Bicuculline methochloride
CAS:(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.
Fórmula:C21H20ClNO6Pureza:98%Cor e Forma:SolidPeso molecular:417.84eeAChE-IN-2
CAS:eeAChE-IN-2 is a potent inhibitor of eeAChE, exhibiting inhibitory potency with an IC50 of 2 nM.Fórmula:C37H40N8O5SCor e Forma:SolidPeso molecular:708.83rel-HDMP 28 hydrochloride
CAS:Rel-HDMP-28 hydrochloride (Compound 2g) is an analogue of methylphenidate, exhibiting selective affinity for the serotonin transporter (SERT) with a binding constant (Ki) of 105 nM [1].Fórmula:C18H22ClNO2Cor e Forma:SolidPeso molecular:319.83U 89843A
CAS:U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.Fórmula:C16H23N5Pureza:99.62%Cor e Forma:SolidPeso molecular:285.39Gepirone
CAS:Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.Fórmula:C19H29N5O2Pureza:99.35% - 99.89%Cor e Forma:SolidPeso molecular:359.47AAK1-IN-4
CAS:AAK1-IN-4 selectively inhibits AAK1 with IC50 of 4.6 nM; penetrates CNS, oral bioactive, potential for studying neuropathic pain.Fórmula:C20H28N4O3Cor e Forma:SolidPeso molecular:372.46MAO-IN-3
CAS:MAO-IN-3 (Compound 5), a reversible and competitive monoamine oxidase (MAO) inhibitor with inhibition constants (K i) of 0.6 μM for MAO A and 0.2 μM for MAO B,Fórmula:C42H54N4O4Pureza:98%Cor e Forma:SolidPeso molecular:678.9VU0029251
CAS:VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM.Fórmula:C10H11N3S2Cor e Forma:SolidPeso molecular:237.34NCS-382 sodium
CAS:NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological diseaseFórmula:C13H13NaO3Pureza:98%Cor e Forma:SolidPeso molecular:240.23Robalzotan
CAS:Robalzotan is a selective 5-HT1A receptor antagonist.Fórmula:C18H23FN2O2Pureza:98%Cor e Forma:SolidPeso molecular:318.39Aβ/tau aggregation-IN-3
CAS:Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 µM in an Aβ-Thioflavin T (Aβ-ThT) functionalFórmula:C23H22N4O3Cor e Forma:SolidPeso molecular:402.45A-424274
CAS:A-424274 is a positive allosteric modulator of α4β2 neuronal nicotinic receptor.Fórmula:C14H15N3Pureza:98%Cor e Forma:SolidPeso molecular:225.29Bisnorcymserine
CAS:Bisnorcymserine reversibly inhibits butyrylcholinesterase, binding Ser(200) and His(440) non-covalently and stacking with Trp(84).Fórmula:C21H25N3O2Pureza:98%Cor e Forma:SolidPeso molecular:351.44BACE1-IN-10
CAS:BACE1-IN-10 is a potent inhibitor of BACE1, demonstrating sub-micromolar activity against recombinant BACE1 (rBACE1) [1].Fórmula:C33H49N5O8SPureza:98%Cor e Forma:SolidPeso molecular:675.84L 687306
CAS:L 687306 is a partial agonist of muscarinic M1 receptors. It is also a highly competitive antagonist at cardiac M2 receptors and ileal M3 muscarinic receptors.Fórmula:C11H15N3OCor e Forma:SolidPeso molecular:205.26Capeserod HCl
CAS:Capeserod HCl, a 5-hydroxytriptamine 4 (5-HT4) receptor agonist, is used potentially for the treatment of Alzheimer's disease.Fórmula:C23H26Cl2N4O4Pureza:98%Cor e Forma:SolidPeso molecular:493.38LY 53857
CAS:LY 53857 is a potent and selective antagonist of 5-HT2 serotonin receptor.Fórmula:C27H36N2O7Cor e Forma:SolidPeso molecular:500.592Frovatriptan
CAS:Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.Fórmula:C14H17N3OPureza:100%Cor e Forma:SolidPeso molecular:243.3JM-1232
CAS:JM-1232 is a sedative and hypnotic drug being researched as a potential anesthetic.Fórmula:C24H27N3O2Cor e Forma:SolidPeso molecular:389.49CGP-54626 free base
CAS:CGP-54626 is a selective antagonist of the GABAB receptor (IC50 = 4 nM ).Fórmula:C18H28Cl2NO3PPureza:98%Cor e Forma:SolidPeso molecular:408.3PHP 501 trifluoroacetate
CAS:GABAA antagonistFórmula:C20H21N3OPureza:98%Cor e Forma:SolidPeso molecular:319.4ADX71441
CAS:ADX71441, a GABAB PAM, lengthens urinary latencies, lessens events & volume, and may aid in alcoholism and bladder pain.Fórmula:C19H15ClF2N4O4Cor e Forma:SolidPeso molecular:436.8FGIN-1-27
CAS:FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).Fórmula:C28H37FN2OPureza:99.86%Cor e Forma:SolidPeso molecular:436.6VU6007477
CAS:VU6007477 is a brain-penetrant M1 muscarinic receptor PAM (EC50 230 nM) used for research on CNS exposure and seizure-related models.Fórmula:C24H26N6O2Pureza:99.67%Cor e Forma:SolidPeso molecular:430.5BMS-933043
CAS:BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) & human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).Fórmula:C16H19N7OPureza:98%Cor e Forma:SolidPeso molecular:325.37Indeloxazine hydrochloride
CAS:Indeloxazine HCl: Serotonin releaser, NE reuptake inhibitor, NMDA antagonist; antidepressant that boosts acetylcholine in rats.Fórmula:C14H18ClNO2Pureza:98%Cor e Forma:SolidPeso molecular:267.75LG 50643
CAS:LG 50643 is a muscarinic antagonist.Fórmula:C24H34INO2Pureza:98%Cor e Forma:SolidPeso molecular:495.44MRK-560
CAS:MRK-560 is an effective and brain-penetrant inhibitor of γ-secretase.Fórmula:C19H17ClF5NO4S2Pureza:98.87%Cor e Forma:SolidPeso molecular:517.92L-772,405
CAS:L-772,405 is a highly selective agonists of h5-HT(1D) receptor.Fórmula:C26H31FN6OPureza:98%Cor e Forma:SolidPeso molecular:462.56Adenylyl cyclase-IN-1
CAS:Adenylyl cyclase-IN-1 is a potential adenylyl cyclase inhibitor for ocular hypotonia research [1].Fórmula:C9H8N2S3Cor e Forma:SolidPeso molecular:240.37AAK1-IN-2
CAS:AAK1-IN-2, a potent (IC50=5.8 nM) AAK1 inhibitor, selective & brain-penetrant, is used for neuropathic pain studies.Fórmula:C20H20N4Cor e Forma:SolidPeso molecular:316.4
