Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(647 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.025 produtos)
- BACE(37 produtos)
- Beta Amilóide(230 produtos)
- CaMK(73 produtos)
- COX(602 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(373 produtos)
- Gama-secretase(62 produtos)
- GluR(265 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(43 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(41 produtos)
- Receptor opioide(327 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5639 produtos de "Neurociência"
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MAO-B-IN-13
CAS:MAO-B-IN-13: a potent, reversible MAO-B inhibitor with BBB penetration, neuroprotective effects; used in Parkinson’s research (IC50=10nM).Fórmula:C18H19NO3Cor e Forma:SolidPeso molecular:297.35Piperidine-4-sulfonic acid
CAS:Piperidine-4-sulfonic acid is a potent GABA agonist, demonstrating an IC50 value of 0.034 μM for the inhibition of H-GABA binding [1].Fórmula:C5H11NO3SPureza:98%Cor e Forma:SolidPeso molecular:165.21SCS
CAS:SCS is a GABAA receptor antagonist.Fórmula:C14H12N2O3Pureza:99.73%Cor e Forma:SolidPeso molecular:256.26AChE-IN-30
CAS:AChE-IN-30 is an acetylcholinesterase inhibitor (IC50 4.4 μM) that reduces oxidative stress and apoptosis, useful for Alzheimer’s disease research models.Fórmula:C22H24N4O2Pureza:99.96%Cor e Forma:SolidPeso molecular:376.45AAK1-IN-2
CAS:AAK1-IN-2, a potent (IC50=5.8 nM) AAK1 inhibitor, selective & brain-penetrant, is used for neuropathic pain studies.Fórmula:C20H20N4Cor e Forma:SolidPeso molecular:316.43β-Hydroxy-lup-20(29)-en-16-one
CAS:3β-Hydroxy-lup-20(29)-en-16-one (compound 9) serves as a dual inhibitor of both AChE and BChE, displaying a preference for BChE with an IC50 of 28.9 μM [1].Fórmula:C30H48O2Cor e Forma:SolidPeso molecular:440.7Pomaglumetad methionil hydrochloride
CAS:LY2140023 hydrochloride: oral methionine prodrug of LY404039, a selective mGlu2/3 agonist, studied for schizophrenia.Fórmula:C12H19ClN2O7S2Pureza:98.57%Cor e Forma:SolidPeso molecular:402.87Diproqualone
CAS:Diproqualone, analogous to methaqualone, exhibits sedative, anxiolytic, anti-inflammatory, and analgesic properties [1].Fórmula:C12H14N2O3Cor e Forma:SolidPeso molecular:234.255CAY10649
CAS:1CAY10649, a thiazolinone compound, directly inhibits 5-lipoxygenase (5-LO) product formation in intact polymorphonuclear leukocytes (PMNL) with an IC50 value of 0.28 μM and in a soluble fraction of an S100 PMNL cell lysate with an IC50 value of 0.09 μM, following stimulation by calcium and arachidonic acid. This activity highlights its potential in mitigating inflammatory responses by targeting the biosynthesis of leukotrienes, substances implicated in various inflammatory processes such as neutrophil chemotaxis, increased vascular permeability, and smooth muscle contraction.Fórmula:C17H12ClNO2SCor e Forma:SolidPeso molecular:329.8GR 125487 sulfamate
CAS:GR 125487 sulfamate is a 5-HT4 receptor antagonist.Fórmula:C19H29FN4O8S2Pureza:98%Cor e Forma:SolidPeso molecular:524.58mAChR antagonist 1
CAS:Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,Fórmula:C19H22N2O2Cor e Forma:SolidPeso molecular:310.39(2R,4R)-APDC
CAS:(2R,4R)-APDC is a selective group II metabotropic glutamate receptors (mGluRs) agonist. It has anticonvulsant and neuroprotective effects.Fórmula:C6H10N2O4Pureza:98%Cor e Forma:SolidPeso molecular:174.15Velusetrag
CAS:Velusetrag(TD-5108), a potent 5-HT4 agonist, is in development for gastroparesis, constipation, and IBS.Fórmula:C25H36N4O5SCor e Forma:SolidPeso molecular:504.64MAO-B-IN-27
CAS:MAO-B-IN-27 (Compound 12c), a monoamine oxidase B (MAO-B) inhibitor, exhibits a potent and selective inhibitory effect on hMAO-B, with an IC50 value of 8.9 nM,Fórmula:C16H17ClF3NOPureza:98%Cor e Forma:SolidPeso molecular:331.765-HT2C agonist-3 free base
CAS:5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), exhibits antipsychotic drug-like activity and inhibits Amphetamine-Fórmula:C19H22FNO2Pureza:98%Cor e Forma:SolidPeso molecular:315.38PQM130
CAS:PQM130 is a Feruloyl-Donepezil Hybrid compound against the neurotoxicity induced by Aβ1-42 oligomer (AβO) and shows anti-inflammatory activity.Fórmula:C23H27NO4Pureza:98.73%Cor e Forma:SolidPeso molecular:381.465-HT2 agonist-1 free base
CAS:Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM,Fórmula:C19H22N2O2Pureza:98%Cor e Forma:SolidPeso molecular:310.39P11149
CAS:P11149: oral AChE inhibitor, crosses BBB, IC50 1.3 μM, based on Galanthamine, aims Alzheimer's research.Fórmula:C27H34ClNO4Cor e Forma:SolidPeso molecular:472.02UNC9994 hydrochloride
CAS:UNC9994 hydrochloride is a selective β-arrestin-biased D2R agonist, Ki of 79 nM, that stimulates β-arrestin and modulates cAMP.Fórmula:C21H23Cl3N2OSCor e Forma:SolidPeso molecular:457.845-HT2C agonist-3
CAS:5-HT2C agonist-3 ((+)-19), a selective 5-HT2C agonist (EC 50: 24 nM, Ki: 78 nM), exhibits antipsychotic-like activity by blocking amphetamine-inducedFórmula:C19H23ClFNO2Pureza:98%Cor e Forma:SolidPeso molecular:351.84BMS-932481
CAS:BMS-932481 is a γ-secretase modulator.Fórmula:C24H24FN7OCor e Forma:SolidPeso molecular:445.49(S)-Bexicaserin
CAS:(S)-Bexcaserin (compound 2) serves as a 5-HT2C receptor agonist, presenting research possibilities in obesity and psychiatric disorders [1].Fórmula:C15H19F2N3OPureza:98%Cor e Forma:SolidPeso molecular:295.33PZ-1190
CAS:PZ-1190, a multitarget ligand for serotonin and dopamine receptors, exhibits potential antipsychotic activity in rodents [1].Fórmula:C27H30N4O2S2Pureza:98%Cor e Forma:SolidPeso molecular:506.68Nemonapride
CAS:Nemonapride is a dopamine D2-like receptor antagonist.Fórmula:C21H26ClN3O2Pureza:98%Cor e Forma:SolidPeso molecular:387.9Anti-amyloid agent-1
CAS:Anti-amyloid agent-1 is a potent compound that inhibits amyloid aggregation, offering a promising approach for research into the treatment of amyloidosis [1].Fórmula:C21H17F3N2O3Cor e Forma:SolidPeso molecular:402.37MAO-B-IN-19
CAS:MAO-B-IN-19, a selective MAO-B inhibitor, exhibits neuroprotective and anti-inflammatory properties and demonstrates an IC50 value of 0.67 μM [1].Fórmula:C15H11FO2Pureza:98%Cor e Forma:SolidPeso molecular:242.255-HT2A receptor agonist-3
CAS:5-HT2A receptor agonist-3 represents the highest selectivity for the human 5-HT2A receptor currently identified, exhibiting a K i of 2.5 nM.Fórmula:C21H26BrNO3Pureza:98%Cor e Forma:SolidPeso molecular:420.34PTAC oxalate
CAS:muscarinic receptor ligandFórmula:C14H21N3O4S2Pureza:98%Cor e Forma:SolidPeso molecular:359.46BACE1-IN-13
CAS:BACE1-IN-13 (Compound 36), an orally active inhibitor of BACE1, exhibits high potency with an IC50 of 2.9 nM and demonstrates greater efficacy in hAβ42 cells (Fórmula:C20H17FN8O2Pureza:98%Cor e Forma:SolidPeso molecular:420.4CGP36216 hydrochloride
CAS:CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].Fórmula:C5H15ClNO2PCor e Forma:SolidPeso molecular:187.6MAO-IN-3
CAS:MAO-IN-3 (Compound 5), a reversible and competitive monoamine oxidase (MAO) inhibitor with inhibition constants (K i) of 0.6 μM for MAO A and 0.2 μM for MAO B,Fórmula:C42H54N4O4Pureza:98%Cor e Forma:SolidPeso molecular:678.94-Chloro-L-phenylalanine
CAS:4-Chloro-L-phenalanine (L-PCPA) is an inhibitor of 5-HT biosynthesis and a non-specific antagonist of tryptophan hydroxylases (TPH1 and TPH2).Fórmula:C9H10ClNO2Pureza:99.76% - 99.96%Cor e Forma:SolidPeso molecular:199.63NCS-382 sodium
CAS:NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological diseaseFórmula:C13H13NaO3Pureza:98%Cor e Forma:SolidPeso molecular:240.235-HT2A&5-HT2C agonist-1
CAS:5-HT2A&5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM.Fórmula:C14H20N2OPureza:98%Cor e Forma:SolidPeso molecular:232.32ADX71441
CAS:ADX71441, a GABAB PAM, lengthens urinary latencies, lessens events & volume, and may aid in alcoholism and bladder pain.Fórmula:C19H15ClF2N4O4Cor e Forma:SolidPeso molecular:436.8BMT-124110
CAS:BMT-124110: AAK1 inhibitor, IC50=0.9 nM, pain relief. BMT-090605: BIKE inhibitor, IC50=17 nM; GAK inhibitor, IC50=99 nM.Fórmula:C21H27N3O3Pureza:98.07%Cor e Forma:SolidPeso molecular:369.46Adipiplon
CAS:Adipiplon(NG2-73, NG273) is a novel selective gamma-aminobutyric acid (GABA) partial agonist.Fórmula:C18H18FN7Cor e Forma:SolidPeso molecular:351.38BChE-IN-20
CAS:BChE-IN-20 (compound 7c) is a potent, selective inhibitor of BChE, demonstrating IC50 values of 105 nM for eqBChE and 2.3 nM for hBChE.Fórmula:C27H39N5O2Cor e Forma:SolidPeso molecular:465.63AChE-IN-19
CAS:AChE-IN-19: strong AChE blocker (IC50: 0.56 μM), hinders Aβ clumps, neuro-protective, non-toxic to SH-SY5Y, for Alzheimer's research.Fórmula:C30H33NO7Cor e Forma:SolidPeso molecular:519.59QR-0217
CAS:QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40.Fórmula:C19H13NO3Cor e Forma:SolidPeso molecular:303.31CGP 64213
CAS:CGP 64213 is a GABAb receptor agonist.Fórmula:C26H36IN2O7PPureza:98%Cor e Forma:SolidPeso molecular:646.45LY320954
CAS:LY320954 is an antagonist of 5-HT2A receptor.Fórmula:C21H26N4O3Pureza:98%Cor e Forma:SolidPeso molecular:382.46MGS-0039
CAS:MGS-0039: Group II mGluR2/3 antagonist, non-serotonergic antidepressant-like effect, AMPA involvement, regulates dopamine in NAc.Fórmula:C15H14Cl2FNO5Pureza:98%Cor e Forma:SolidPeso molecular:378.18BT-GSI
BT-GSI: γ-secretase inhibitor targeting Notch, anti-myeloma & anti-resorptive for multiple myeloma/bone disease research.Fórmula:C26H46BrN5O10P2Cor e Forma:SolidPeso molecular:730.52NAS181
CAS:rat 5-HT1B receptor antagonistFórmula:C21H34N2O10S2Pureza:98%Cor e Forma:SolidPeso molecular:538.63VU0453595
CAS:VU0453595 is a M1 positive allosteric modulator (PAM).
Fórmula:C18H15FN4OPureza:99.91%Cor e Forma:SolidPeso molecular:322.34GABAA receptor agent 2 TFA
CAS:Potent GABAA antagonist; IC50: 24 nM (α1β2γ2), Ki: 28 nM (rat); inactive on human GABA transporters.Fórmula:C22H22F3N3O3Cor e Forma:SolidPeso molecular:433.42(S)-Renzapride
(S)-Renzapride (BRL 24924), 5-HT4 agonist (Ki 115 nM), 5HT2b/5HT3 antagonist, for C-IBS study.Fórmula:C16H22ClN3O2Cor e Forma:SolidPeso molecular:323.82eeAChE-IN-2
CAS:eeAChE-IN-2 is a potent inhibitor of eeAChE, exhibiting inhibitory potency with an IC50 of 2 nM.Fórmula:C37H40N8O5SCor e Forma:SolidPeso molecular:708.83GR-127935
CAS:GR-127935 is a potent and selective 5-HT1B/1D receptor antagonist.Fórmula:C29H31N5O3Cor e Forma:SolidPeso molecular:497.59Mesembrine
CAS:Mesembrine is an alkaloid, a 5-HT transporter inhibitor (K i 1.4 nM), and inhibits PDE4B (IC50 7.8 μM).Fórmula:C17H23NO3Cor e Forma:SolidPeso molecular:289.37AMG-8718
CAS:AMG-8718, an oral BACE1 blocker (IC50: 0.0007 μM), also inhibits BACE2 (IC50: 0.005 μM), lowering CSF and Aβ40 brain levels.Fórmula:C25H19FN4O3Cor e Forma:SolidPeso molecular:442.44UNC9994
CAS:UNC9994 is a β-arrestin-biased dopamine D₂ receptor agonist (β-arrestin EC50 = 50 nM; Emax = 97%) with robust in vivo antipsychotic drug-like activities.Fórmula:C21H22Cl2N2OSCor e Forma:SolidPeso molecular:421.38MAO-B-IN-1
CAS:MAO-B-IN-1 is a monoamine oxidase B inhibitor and can be used for the research of neurological diseases.Fórmula:C16H14F3N3O2SPureza:98%Cor e Forma:SolidPeso molecular:369.36GYKI-46903 HCl
CAS:GYKI-46903 is a noncompetitive 5-HT3 receptor antagonist.Fórmula:C17H21ClFNO2Cor e Forma:SolidPeso molecular:325.81Flesinoxan
CAS:Flesinoxan is a hypotensive agent and is an effective, high affinity, and selective 5-hydroxytryptamine1A receptor agonist (EC50: 24 nM).Fórmula:C22H26FN3O4Cor e Forma:SolidPeso molecular:415.46NAS-181
CAS:NAS-181 is a potent and selective rat 5-hydroxytryptamine 1B (r5-HT1B) antagonist (Ki: 47 nM).NAS-181 enhances the accumulation of 5-HTP in rat brain regions.Fórmula:C20H30N2O7SCor e Forma:SolidPeso molecular:442.53CGP 55845 hydrochloride
CAS:CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC 50 of 6 nM which can be used in neurological research [1] [2].Fórmula:C18H23Cl3NO3PCor e Forma:SolidPeso molecular:438.71LY3202626
CAS:LY3202626, an amyloid precursor protein secretase (BACE protein) inhibitor, is used for the treatment of Alzheimer's disease.Fórmula:C22H20F2N8O2SPureza:98%Cor e Forma:SolidPeso molecular:498.51VU 0255035
CAS:VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.
Fórmula:C18H20N6O3S2Pureza:98.09% - 98.1%Cor e Forma:SolidPeso molecular:432.52Wf-516
CAS:Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressantFórmula:C25H25Cl2N3O4Pureza:98%Cor e Forma:SolidPeso molecular:502.39N-Demethyl MK-6884
CAS:N-Demethyl MK-6884 (compound 34) is an M4 mAChR modulator for Alzheimer's and related disease research.Fórmula:C24H23N5OCor e Forma:SolidPeso molecular:397.47YM348
CAS:YM348 is an effective and orally active 5-HT2C receptor agonist. YM348 also shows a high affinity for the cloned human 5-HT2C receptor (Ki: 0.89 nM).Fórmula:C14H17N3OPureza:98%Cor e Forma:SolidPeso molecular:243.3MIN-117
CAS:MIN-117, a SSRI/5-HT receptor antagonist, is potentially used for the treatment of depression.Fórmula:C25H26Cl3N3O4Pureza:98%Cor e Forma:SolidPeso molecular:538.85(±)-Fabesetron hydrochloride
CAS:FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.Fórmula:C18H20ClN3OPureza:98%Cor e Forma:SolidPeso molecular:329.82Brasofensine sulfate
CAS:Brasofensine sulfate is a dopamine reuptake inhibitor.Fórmula:C16H22Cl2N2O5SCor e Forma:SolidPeso molecular:425.33Fosthiazate
CAS:Fosthiazate is a broad-spectrum nematicide that combats a range of plant parasitic nematodes such as Meloidogyne spp., Globodera spp., and Pratylenchus spp., byFórmula:C9H18NO3PS2Pureza:97.78%Cor e Forma:SolidPeso molecular:283.35FPPQ
CAS:FPPQ blocks 5-HT3 and 5-HT6 receptors (Ki: 0.9 & 3 nM) and may improve psychosis and cognition.Fórmula:C21H19FN4O2SCor e Forma:SolidPeso molecular:410.46rel-HDMP 28 hydrochloride
CAS:Rel-HDMP-28 hydrochloride (Compound 2g) is an analogue of methylphenidate, exhibiting selective affinity for the serotonin transporter (SERT) with a binding constant (Ki) of 105 nM [1].Fórmula:C18H22ClNO2Cor e Forma:SolidPeso molecular:319.83AMPA receptor antagonist-3
CAS:AMPA receptor antagonist-3 is an AMPA receptor antagonist.Fórmula:C20H19N5O2SPureza:99.79%Cor e Forma:SolidPeso molecular:393.46Ref: TM-T61813
1mg185,00€5mg425,00€1mL*10mM (DMSO)455,00€10mg625,00€25mg938,00€50mg1.311,00€100mg1.795,00€VU6004909
CAS:VU6004909 is an mGlu5 receptor orthosteric modulator that reverses MK801-induced increased cortical activity and cognitive dysfunction.Fórmula:C21H15FN2O4Pureza:96.68% - 98.44%Cor e Forma:SolidPeso molecular:378.35SB 216641 hydrochloride
CAS:SB 216641 hydrochloride (SB-216641A) is a 5-HT1B/D receptor antagonist with anxiolytic properties.Fórmula:C28H31ClN4O4Pureza:98.06% - 99.23%Cor e Forma:SolidPeso molecular:523.02Tematropium
CAS:Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.Fórmula:C21H31NO8SPureza:99.89%Cor e Forma:SolidPeso molecular:457.54Ref: TM-T10732
1mg147,00€5mg356,00€1mL*10mM (DMSO)413,00€10mg558,00€25mg880,00€50mg1.179,00€100mg1.603,00€200mg2.152,00€γ-Secretase-IN-1
CAS:γ-Secretase-IN-1 is a γ-secretase inhibitor that displays partial antiproliferative activity against T-47D cells.Fórmula:C27H24F2N4O3Pureza:99.56%Cor e Forma:SolidPeso molecular:490.5Ref: TM-T3521
1mg120,00€5mg385,00€1mL*10mM (DMSO)416,00€10mg618,00€25mg1.224,00€50mg1.648,00€100mg2.232,00€Didesmethyl cariprazine
CAS:Didesmethyl cariprazine, Cariprazine's active metabolite, treats schizophrenia/bipolar with D3/D2 affinity; half-life 1-3 weeks.Fórmula:C19H28Cl2N4OPureza:99.52%Cor e Forma:SolidPeso molecular:399.36AMPA receptor modulator-1
CAS:AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.
Fórmula:C16H11ClF3NO2Pureza:99.93%Cor e Forma:SolidPeso molecular:341.71Atabecestat
CAS:Atabecestat (JNJ-54861911) is an oral BACE1 inhibitor for Alzheimer's treatment with strong brain uptake and lasting PK/PD effects.Fórmula:C18H14FN5OSPureza:99.21% - 99.77%Cor e Forma:SolidPeso molecular:367.4Ref: TM-T14338
1mg123,00€5mg295,00€1mL*10mM (DMSO)326,00€10mg477,00€25mg954,00€50mg1.279,00€100mg1.728,00€R-(+)-EU-1180-453
CAS:R-(+)-EU-1180-453 is a novel GluN2C/D selective NMDAR-positive modulator for the study of neurological disorders.Fórmula:C22H21FN2O3Pureza:99.63%Cor e Forma:SolidPeso molecular:380.41TZ3O
CAS:TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment in Scopolamine-induced Alzheimer's type model in rats.Fórmula:C18H13NO4SPureza:99.84%Cor e Forma:SolidPeso molecular:339.37BuChE-IN-TM-10
CAS:TM-10: Potent BuChE inhibitor, IC50 8.9 nM, disaggregates Aβ, antioxidant, BBB penetrant, may treat Alzheimer's.Fórmula:C32H38N2O3Pureza:99.54%Cor e Forma:SolidPeso molecular:498.66Osemozotan HCl
CAS:Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder.Fórmula:C19H22ClNO5Pureza:98.87% - 99.63%Cor e Forma:SolidPeso molecular:379.84WAY-607695
CAS:WAY-607695 is a potential 5-HT1A receptor agonist.Fórmula:C13H12FNO2Pureza:99.82%Cor e Forma:SolidPeso molecular:233.24PXS-5153A
CAS:PXS-5153A rapidly inhibits lysyl oxidase 2/3 enzymes, blocks activity in 15 mins, and reduces fibrosis.Fórmula:C20H25Cl2FN4O2SPureza:99.58%Cor e Forma:SolidPeso molecular:475.41PXS-5120A
CAS:PXS-5120A is an irreversible fluoroallylamine Lysyl Oxidase-like 2/3 (LOXL2/3) inhibitor with anti-fibrotic activity.Fórmula:C22H25ClFN3O4SPureza:97.02%Cor e Forma:SolidPeso molecular:481.97Ref: TM-T12584
1mg205,00€2mg293,00€5mg462,00€1mL*10mM (DMSO)502,00€10mg612,00€25mg893,00€50mg1.224,00€100mg1.639,00€Lumateperone
CAS:Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).Fórmula:C24H28FN3OPureza:99.68% - 99.91%Cor e Forma:SolidPeso molecular:393.5BMS-986176
CAS:AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).
Fórmula:C19H23F4N3OPureza:98.58% - 98.7%Cor e Forma:SolidPeso molecular:385.4MDR-1339
CAS:MDR-1339 is a blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.Fórmula:C20H22O4Pureza:98.57%Cor e Forma:SolidPeso molecular:326.39SB-616234-A
CAS:SB-616234-A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant activity.Fórmula:C32H36ClN5O3Pureza:99.72%Cor e Forma:SolidPeso molecular:574.11Pareptide monohydrochloride
CAS:Pareptide monohydrochloride is a metabolically stable analog of melatonin inhibitor (MIF).Fórmula:C14H27ClN4O3Pureza:98%Cor e Forma:SolidPeso molecular:334.848 Hydroxy PIPAT oxalate
CAS:8 Hydroxy PIPAT oxalate is a selective 5-HT1A receptor agonist that enhances the spontaneous release of histamine by promoting the degranulation of mast cells in guinea pig and human intestinal preparations. By activating the serotonin signaling pathway, this compound demonstrates potential in regulating gastrointestinal functions and offers insight into the management and suppression of functional gastrointestinal disorders such as irritable bowel syndrome. Its effects in increasing histamine release could play a crucial role in gastrointestinal regulation.Fórmula:C18H24INO5Cor e Forma:SolidPeso molecular:461.295-IAI hydrochloride
CAS:5-IAI hydrochloride is a psychoactive analog of para-iodoamphetamine. 5-IAI hydrochloride significantly reduces serotonin uptake sites and hippocampal serotonin levels in rats.Fórmula:C9H11ClINCor e Forma:SolidPeso molecular:295.548Poskine
CAS:Poskine is an anticholinergic and central nervous system depressant. It is utilized in research related to Parkinson's disease and motion sickness.Fórmula:C20H25NO5Cor e Forma:SolidPeso molecular:359.42SGE-516
CAS:SGE516: neuroactive steroid, enhances GABAA, lowers neuronal activity, protects from seizures.Fórmula:C23H35N3O2Pureza:98%Cor e Forma:SolidPeso molecular:385.54(+)-Sparteine sulfate pentahydrate
(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.Fórmula:C15H38N2O9SCor e Forma:SolidPeso molecular:422.54DSP-1053 benzenesulfonate
CAS:DSP-1053: Benzylpiperidine-based, potent SERT inhibitor (Ki=1.02nM), partial 5-HT1A receptor agonist (Ki=5.05nM), antidepressant.Fórmula:C32H38BrNO7SCor e Forma:SolidPeso molecular:660.625-HT6R/MAO-B modulator 1
5-HT6R/MAO-B modulator 1 blocks 5-HT6R and permanently inhibits MAO-B, protects glial cells, and reverses memory loss.Fórmula:C33H38N4O3SCor e Forma:SolidPeso molecular:570.74CaMKIIα-IN-1
CaMKIIα-IN-1 (Compound 4d) is an orally active inhibitor of Ca 2+ /calmodulin-dependent protein kinase II α (CaMKIIα) with a Kd of 219 nM for CaMKIIα WT hub.Fórmula:C14H11ClO4Cor e Forma:SolidPeso molecular:278.69Aβ42-IN-1
CAS:Aβ42-IN-1, compound 1v, is a novel, potent and orally active γ-secretase modulator (GSM).Fórmula:C29H27ClN4O2Pureza:98%Cor e Forma:SolidPeso molecular:499BPN-15606 besylate
BPN-15606 besylate is a potent oral γ-secretase regulator reducing Aβ42 and Aβ40 with good pharmacokinetics. IC50: 7 nM (Aβ42), 17 nM (Aβ40).Fórmula:C29H29FN6O4SCor e Forma:SolidPeso molecular:576.64Beloxepin
CAS:Beloxepin is an oral dual selective inhibitor of serotonin and norepinephrine uptake.Fórmula:C19H21NO2Pureza:98%Cor e Forma:SolidPeso molecular:295.38
