Neurociência

Applications Etafedrine is the N-ethylated analogue of Ephedrine (E575000). Etafedrine is a long-acting bronchodilator that …

Impurity Rivastigmine USP Related Compound F Stability Light Sensitive Applications A related compound of Rivastigmine …

Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = …

Applications 3-(Diethylamino)-2,2-dimethyl-1-propanol 4-Nitrobenzoate Hydrochloride is an intermediate in the preparation of Dimethocaine Hydrochloride (D460545).

Applications D-α-Methyl DOPA (M303790) derivative.

Applications Homoveratric Acid is a dopamine metabolite that inhibits brain mitochondrial respiration via monoamine oxidase/H2O2-dependent …

Applications 3-(Diethylamino)-2,2-dimethyl-1-propanol 4-Nitrobenzoate-d4 Hydrochloride is an intermediate in the preparation of Dimethocaine-d4 Hydrochloride (D460547).

Applications (4-((Pyrrolidin-1-ylsulfonyl)methyl)phenyl)carbamic Acid tert-Butyl Ester is an impurity in the synthesis of Almotriptan (A575200), a …

Applications (S)-3-Amino-6,7-dihydroxy-hydrocoumarin Hydrochloride is a derivative of the amino acid L-DOPA (D533751) with neurotoxic properties …

Applications Isotope labelled 9-Methylharmine, an compound studied in the detection of photosensitizers methyl-carbolines induced DNA …

Applications N-Demethylricinine is a demethylated metabolite of Ricinine (R495550), an alkaloid extract from the castor-oil …

Applications (8β)-8-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-6-methylergoline is an protected intermediate in the synthesis of cabergoline (C050000) which is a …

Applications N-Tosyl-L-aspartic Acid is a protected L-Aspartic Acid, a nonessential amino acid. References Singh, S. …

Applications 2-Hydroxy-1-phenylpentane is an impurity of Prolintane (P756100) synthesis. References Hucker, H.B. et al.: Experientia, …

4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert …

BMS 193885 is a selective and competitive neuropeptide Y(1) receptor antagonist with affinity of 3.3 …

Eledoisin Related Peptide (Eledoisin RP) is a tachykinin receptor ligand.

Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester functioning as a central cannabinoid receptor (CB1) antagonist …

Naltrindole hydrochloride is a selective and non-peptide δ opioid receptor antagonist(Ki = 0.02 nM).

Nimbin is an anti-pyretic, can be used to treat arthritis, hypoglycaemia, peptic ulcers, anti-secretory activity, …

YM-254890, a macrocyclohexapeptide isolated from Chromobacterium sp, is a selective and potent inhibitor of Gαq/11 …

Eledoisin (Eledone peptide) is a specific agonist of NK2 and NK3 receptors.Eledoisin is an undecapeptide …

(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).

α-Muricholic acid is the most abundant primary bile acid in rodents.

Peonidin chloride has antioxidant activity. Peonidin has show potent inhibitory and apoptotic effects on cancer …

Cetirizine D8 dihydrochloride is a deuterium-labeled Cetirizine. Cetirizine is a second-generation antihistamine and a long-acting …

4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory …

(S)-Coclaurine (Coclaurine) is an antagonist of nAChR isolated from Sarcopetalum harveyanum.

Fustin is the phytogenic flavanol component of the plant Rhus verniciflua Stokes. Fustin shows protective …

Mahanimbine is found in the roots, leaves and stems of Murraya koenigii and is an …

(-)-Pluviatolide can inhibit electrically-induced and acetylcholine-induced contraction in the isolated guinea-pig ileum.

Gliotoxin, a Wnt signaling pathway inhibitor, induces growth inhibition and apoptosis in multiple colorectal cancer …

Bacopaside X (9.06 μM) showed binding affinity towards the D1 receptor.

Cariprazine D6 (RGH-188 D6) is a deuterium-labeled Cariprazine. Cariprazine is an antipsychotic agent (D3 receptors, …

Nimesulide D5 is a deuterium labeled Nimesulide. Nimesulide is a selective inhibitor OF COX-2(IC50s of …

Mirtazapine D3 is a deuterium labeled Mirtazapine. Mirtazapine is an inhibitor of 5-HT receptor .

DPDPE is selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens …

L-689560 is widely used as a radiolabeled ligand in binding studies and used to study …

NF023 hexasodium is a selective and competitive P2X1 receptor antagonist, with IC50 values of 0.21 …

Pimozide D4 is a deuterium labeled Pimozide.

NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, …

Reboxetine (Norebox) is an antidepressant drug used in the treatment of clinical depression, panic disorder …

Ciproxifan (FUB-359) is a highly effective and specific histamin H3-receptor antagonist (IC50: 9.2 nM).

Pardoprunox (SLV-308) is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist …

Diclofensine (Ro 8-4650) is a monoamine reuptake inhibitor that blocks dopamine (IC50=0.74 nM), norepinephrine (IC50=2.3 …

Applications Cevimeline derivative.

Applications (S)-Benzylphenobarbital is a derivative of Phenobarbital (P316760), which is an Anticonvulsant; sedative; hypnotic. References …

Applications 2-[[3-(Dimethylamino)propyl]thio]benzenamine is a reagent in the synthesis of Cinanserin (C441903) which is a serotonin …

Applications rel-α-​Amino-​β-​hydroxy-​1,3-benzodioxole-5-methyl Propanoate is an intermediate in the synthesis of (2S,3R)-2-Amino-3-(benzo[d][1,3]dioxol-5-yl)-3-hydroxypropanoic Acid (A400545). (2S,3R)-2-Amino-3-(benzo[d][1,3]dioxol-5-yl)-3-hydroxypropanoic Acid …

Applications A ring-opened analog of Fentanyl (F274990). An opioid analgesic with potency similar to morphine. …

Stability Very Hygroscopic Applications Antihypertensive agent. References Beckett, et al.: J. Pharm. Pharmacol., 7, 433 …