Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(939 produtos)
- ACK(1 produtos)
- AChR(575 produtos)
- ATP Citrato Liase(16 produtos)
- Receptor adrenérgico(2.945 produtos)
- BACE(36 produtos)
- Beta Amilóide(205 produtos)
- CaMK(69 produtos)
- COX(561 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor GABA(336 produtos)
- Gama-secretase(59 produtos)
- GluR(255 produtos)
- GlyT(24 produtos)
- Receptor de Histamina(358 produtos)
- LRRK2(33 produtos)
- Receptor de Melatonina(24 produtos)
- NMDAR(28 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(297 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5398 produtos de "Neurociência"
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D3/5-HT receptor modulator-1
CAS:<p>D3/5-HT receptor modulator-1 (compound 5i) is a selective antagonist of the dopamine D3 and 5-HT2A receptors, and a partial agonist at the 5-HT1A receptor. It exhibits Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for the dopamine D3, 5-HT2A, and 5-HT1A receptors respectively. The compound shows lower affinity for the dopamine D2 receptor, 5-HT2C receptor, and hERG channel. D3/5-HT receptor modulator-1 possesses atypical antipsychotic properties.</p>Fórmula:C24H29N3O2Cor e Forma:SolidPeso molecular:391.506AChE/BuChE-IN-3
CAS:<p>AChE/BuChE-IN-3 inhibits AChE (IC50: 0.65 μM), BuChE (IC50: 5.77 μM), crosses BBB, and hinders Aβ1-42 aggregation for Alzheimer's research.</p>Fórmula:C30H30F3N3O6Cor e Forma:SolidPeso molecular:585.57AChE/BChE-IN-1
<p>AChE/BChE-IN-1: dual AChE/BChE inhibitor, IC50 of 1.06 nM/7.3 nM, crosses blood-brain barrier, with antioxidant properties for Alzheimer's research.</p>Fórmula:C32H35ClN6O3Cor e Forma:SolidPeso molecular:587.11γ-secretase modulator 5
<p>Compound 22d is a GSM that crosses the blood-brain barrier, inhibits Aβ42 production (IC50: 60 nM), and may help study Alzheimer's.</p>Cor e Forma:SolidAChE-IN-5
<p>AChE-IN-5: oral, crosses blood-brain barrier, targets AChE/5-HT1A/SERT, potent with 2.29 nM IC50.</p>Fórmula:C38H45N5OCor e Forma:SolidPeso molecular:587.8Revexepride
CAS:<p>Revexepride, a 5-HT4 agonist, may boost CYP3A4, used for treating GERD.</p>Fórmula:C21H32ClN3O4Pureza:98%Cor e Forma:SolidPeso molecular:425.95BACE-1 inhibitor 2
CAS:<p>BACE-1 Inhibitor 2 is a potent, CNS-permeable inhibitor of BACE-1, exhibiting an IC50 value of 1.5 nM in enzymatic assays [1].</p>Fórmula:C21H21F4N5O3Cor e Forma:SolidPeso molecular:467.42BChE-IN-2
<p>BChE-IN-2, a pyrimidine/pyridine derivative, potently inhibits BChE (Ki 0.099 μM) and shows promise in AD research.</p>Fórmula:C22H31N5Cor e Forma:SolidPeso molecular:365.52MAO-B-IN-10
<p>MAO-B-IN-10: Potent, selective MAO-B inhibitor; crosses blood-brain barrier; IC50 5.3 μM; reduces Aβ aggregation 58.2%, disaggregates 43.3%.</p>Fórmula:C23H26N2O4Cor e Forma:SolidPeso molecular:394.46LP 12 hydrochloride hydrate
<p>LP 12 hydrochloride hydrate: potent, selective 5-HT7 agonist (Ki: 0.13 nM); less affinity for D2, 5-HT1A/2A receptors.</p>Fórmula:C32H39N3O·HCl·xH2OCor e Forma:Solid25B-NBOH hydrochloride
CAS:<p>25B-NBOH hydrochloride is a phenethylamine that exhibits high affinity for serotonin (5-HT) receptors 5-HT2A and 5-HT2C, with pKi values of 8.3 and 9.4, respectively.</p>Fórmula:C17H21BrClNO3Cor e Forma:SolidPeso molecular:402.711AChE-IN-83
CAS:<p>AChE-IN-83 (compound f1) is an AChE inhibitor that suppresses nematode growth and acetylcholinesterase activity in rice seeds while being safe for the seeds. It specifically targets Aphelenchoides besseyi, with an LC50 of 19.0 μg/mL over 48 hours. AChE-IN-83 impedes nematode populations and behaviors in rice seeds, damages the nematode cuticle, and induces reactive oxygen species, lipofuscin, and lipid generation within the nematodes.</p>Fórmula:C10H7ClN2O2SCor e Forma:SolidPeso molecular:254.6935-HT1A modulator 4
CAS:<p>5-HT1A modulator 4 (Compound 1) is a ligand for the 5-HT receptor, with Ki values of 2.18 μM for 5-HT1A and 19.7 μM for 5-HT2A.</p>Fórmula:C9H14N4Cor e Forma:SolidPeso molecular:178.234MMB-4
CAS:<p>MMB-4 is an oxime that can reactivate cholinesterases (cholinesterases) which have been inactivated due to exposure to organophosphates such as Sarin or Soman.</p>Fórmula:C13H14Br2N4O2Cor e Forma:SolidPeso molecular:418.084MAO-B-IN-40
CAS:<p>MAO-B-IN-40 (3a) is an inhibitor of MAOB, exhibiting an IC50 value of 0.493 μM against hMAOB, and demonstrates significant neuroprotective and antioxidant effects. MAO-B-IN-40 (3a) is applicable in Parkinson's disease research.</p>Fórmula:C17H15N3O3Cor e Forma:SolidPeso molecular:309.319ChE/Aβ1-42-IN-1
<p>ChE/Aβ1-42-IN-1 (compound 28) is a potent aggregation inhibitor of ChE and Aβ 1-42 with excellent BBB permeability.</p>Fórmula:C19H24N2O3Cor e Forma:SolidPeso molecular:328.41BChE-IN-5
<p>BChE-IN-5: potent, selective BChE inhibitor (IC50: 2.8 nM), more effective on hBChE, potential in Alzheimer's research.</p>Fórmula:C30H42N4OCor e Forma:SolidPeso molecular:474.68BACE1-IN-2
CAS:<p>BACE1-IN-2 is a BACE1 inhibitor (IC50: 22 nM).</p>Fórmula:C19H15F4N5O2Pureza:98%Cor e Forma:SolidPeso molecular:421.35YNT-3708
CAS:<p>YNT-3708 is an orexin receptor (OXR) agonist, exhibiting EC50 values of 14.6 nM for OX1R and 277 nM for OX2R.</p>Fórmula:C35H36N4O6SCor e Forma:SolidPeso molecular:640.749eeAChE-IN-1
<p>eeAChE-IN-1 is a strong inhibitor of eeAChE (IC50: 23 nM).</p>Fórmula:C27H30N6O5SCor e Forma:SolidPeso molecular:550.63
