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Neurociência

Neurociência

Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.

Subcategorias de "Neurociência"

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Foram encontrados 5400 produtos de "Neurociência"

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  • Amyloid-β-IN-3
    Targetmol
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    Amyloid-β-IN-3

    CAS:
    <p>Amyloid-β-IN-3 (EX.113) is a selective inhibitor of γ-secretase. It demonstrates inhibitory activity on Aβ42 secretion in H4 cells, with an EC50 value of 148 nM. By modulating the catalytic activity of γ-secretase, Amyloid-β-IN-3 decreases Aβ42 production, thereby alleviating neurotoxicity caused by Aβ deposition. It holds potential for Alzheimer's disease (AD) research.</p>
    Fórmula:C22H21F2N3O2
    Cor e Forma:Solid
    Peso molecular:397.42

    Ref: TM-T207233

  • Tebideutorexant
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    Tebideutorexant

    CAS:
    <p>Tebideutorexant, an orexin-1 receptor antagonist, shows anti-panic effects in rodents and humans, providing a tool for stress response and psychiatric research.</p>
    Fórmula:C23H16D2F4N4O2
    Pureza:98.89%
    Cor e Forma:Solid
    Peso molecular:460.42

    Ref: TM-T70332

  • Logotipo do CymitQuimica
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    AChE-IN-8

    <p>AChE-IN-8 (Compound 19), potent acetylcholinesterase blocker; IC50 = 1.95 μM; potential Alzheimer's treatment.</p>
    Fórmula:C20H22N4O2S
    Cor e Forma:Solid
    Peso molecular:382.48

    Ref: TM-T61648

  • LY 541850
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    LY 541850

    CAS:
    <p>LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively.LY 541850 is claimed from human</p>
    Fórmula:C9H13NO4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:199.2

    Ref: TM-T11906

  • Logotipo do CymitQuimica
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    Monoamine Oxidase B inhibitor 2

    <p>MAO-B inhibitor 2: potent, reversible, oral, selective (IC50=1.33 nM), BBB-penetrant, with anti-oxidant and anti-inflammatory effects for Parkinson's study.</p>
    Fórmula:C19H19FO3
    Cor e Forma:Solid
    Peso molecular:314.35

    Ref: TM-T60806

  • Logotipo do CymitQuimica
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    K203

    <p>K203 is a potent tabun-inhibited AChE reactivator and is an important antidote to organophosphorus poisoning.</p>
    Fórmula:C16H18Br2N4O2
    Cor e Forma:Solid
    Peso molecular:458.15

    Ref: TM-T62857

  • P2X4 antagonist-1
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    P2X4 antagonist-1

    CAS:
    <p>P2X4 antagonist-1 is a potent P2X4 receptor antagonist used in the study of neurological, cardiovascular, and immune system diseases.</p>
    Fórmula:C20H15Cl3N2O4S
    Pureza:99.9%
    Cor e Forma:Solid
    Peso molecular:485.77

    Ref: TM-T87086

  • CVN636
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    CVN636

    CAS:
    <p>CVN636, a potent and selective allosteric agonist for the mGluR7 receptor, exhibits oral activity and CNS permeability [1], with an EC50 of 7 nM for human</p>
    Fórmula:C19H20FNO4S
    Cor e Forma:Solid
    Peso molecular:377.43

    Ref: TM-T78090

  • LRRK2-IN-3
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    LRRK2-IN-3

    CAS:
    <p>LRRK2-IN-3: potent, selective oral LRRK2 blocker, BBB-penetrant, IC50 of 0.6 nM in hPBMCs, for Parkinson's research.</p>
    Fórmula:C25H29ClF2N6O2
    Cor e Forma:Solid
    Peso molecular:518.99

    Ref: TM-T63620

  • Logotipo do CymitQuimica
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    β-Secretase Inhibitor III

    <p>β-Secretase Inhibitor III is a highly selective inhibitor of BACE1 with a Ki value of 0.13 nM.</p>
    Fórmula:C20H20F2N4O3S
    Cor e Forma:Solid
    Peso molecular:434.46

    Ref: TM-T62455

  • Remlifanserin
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    Remlifanserin

    CAS:
    <p>Remlifanserin is a potent inverse agonist of the serotonin receptor (5-HT2A).</p>
    Fórmula:C24H29F2N3O2
    Cor e Forma:Solid
    Peso molecular:429.50

    Ref: TM-T201055

  • Cyproflanilide
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    Cyproflanilide

    CAS:
    <p>Cyproflanilide is a GABAR antagonist that exhibits high activity against a variety of pests, including those from the Lepidoptera, Coleoptera, and Thysanoptera orders.</p>
    Fórmula:C28H17BrF12N2O2
    Cor e Forma:Solid
    Peso molecular:721.33

    Ref: TM-T201028

  • P2X7 receptor antagonist-5
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    P2X7 receptor antagonist-5

    CAS:
    <p>P2X7 receptor antagonist-5 (compound 13a) is a potent, orally active, and long-lasting antagonist of the P2X7 receptor.</p>
    Fórmula:C21H17F3N6O3S2
    Cor e Forma:Solid
    Peso molecular:522.52

    Ref: TM-T201089

  • Logotipo do CymitQuimica
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    Monoamine Oxidase B inhibitor 1

    <p>Potent, selective MAO-B inhibitor; reversible; oral; crosses BBB; IC50=0.02 nM; potential for Parkinson's research.</p>
    Fórmula:C18H15FO3
    Cor e Forma:Solid
    Peso molecular:298.31

    Ref: TM-T60656

  • LB-102
    Targetmol
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    LB-102

    CAS:
    <p>LB-102 is an orally active inhibitor of dopamine D2, D3, and serotonin 5-HT7 receptors, utilized in the study of schizophrenia and other psychiatric disorders.</p>
    Fórmula:C18H29N3O4S
    Cor e Forma:Solid
    Peso molecular:383.51

    Ref: TM-T200914

  • Logotipo do CymitQuimica
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    AChE-IN-10

    <p>AChE-IN-10 (24r) inhibits AChE (IC50=2.4 nM), reducing amyloid buildup, tau phosphorylation, and promotes neuron health.</p>
    Fórmula:C23H27F2NO4S
    Cor e Forma:Solid
    Peso molecular:451.53

    Ref: TM-T62743

  • Aβ aggregation-IN-1
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    Aβ aggregation-IN-1

    CAS:
    <p>Aβ aggregation-IN-1 (Compound 1b) is an inhibitor of amyloid-beta precursor protein. It suppresses the aggregation and disaggregation of amyloid-beta fibrils with IC50 values of 3.92 and 7.19 M, respectively. Additionally, Aβ aggregation-IN-1 reduces malondialdehyde formation in neuronal cells, increases intracellular levels of reduced glutathione (GSH), and inhibits caspase 3.</p>
    Fórmula:C9H8BF3O2
    Cor e Forma:Solid
    Peso molecular:215.965

    Ref: TM-T204182

  • hAChE/Aβ1-42-IN-1
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    hAChE/Aβ1-42-IN-1

    CAS:
    <p>Compound 16 (hAChE/Aβ1-42-IN-1) is a potent inhibitor targeting both hAChE and Aβ1-42 aggregation, demonstrating considerable safety in hepG2 cell lines and</p>
    Fórmula:C20H24N6O
    Cor e Forma:Solid
    Peso molecular:364.44

    Ref: TM-T61388

  • Logotipo do CymitQuimica
    Targetmol
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    (+)-Sparteine sulfate pentahydrate

    <p>(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.</p>
    Fórmula:C15H38N2O9S
    Cor e Forma:Solid
    Peso molecular:422.54

    Ref: TM-T62265

  • DL-AP5 lithium
    Targetmol
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    DL-AP5 lithium

    CAS:
    <p>DL-AP5 (2-APV) lithium is a competitive antagonist of the NMDA (N-Methyl-D-aspartate) receptor. It exhibits notable analgesic activity and specifically blocks channels in the rabbit retina.</p>
    Fórmula:C5H11LiNO5P
    Cor e Forma:Solid
    Peso molecular:203.06

    Ref: TM-T201724