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Neurociência

Neurociência

Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.

Subcategorias de "Neurociência"

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Foram encontrados 5397 produtos de "Neurociência"

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  • PF-06648671
    Targetmol
    + Info

    PF-06648671

    CAS:
    <p>PF-06648671 is a γ-secretase modulator for the treatment of neurodegenerative and/or neurological disorders.</p>
    Fórmula:C25H23ClF4N4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:538.92

    Ref: TM-T24621

  • SB 224289
    Targetmol
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    SB 224289

    CAS:
    <p>SB 224289: selective 5-HT1B antagonist, pKi 8.2, 60x selectivity, effective orally.</p>
    Fórmula:C32H32N4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:520.62

    Ref: TM-T19690

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    BPN-15606 besylate

    <p>BPN-15606 besylate is a potent oral γ-secretase regulator reducing Aβ42 and Aβ40 with good pharmacokinetics. IC50: 7 nM (Aβ42), 17 nM (Aβ40).</p>
    Fórmula:C29H29FN6O4S
    Cor e Forma:Solid
    Peso molecular:576.64

    Ref: TM-T64081

  • AChE/BChE/MAO-B-IN-5
    Targetmol
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    AChE/BChE/MAO-B-IN-5

    CAS:
    <p>AChE/BChE/MAO-B-IN-5 is a multi-target inhibitor capable of crossing the blood-brain barrier, targeting cholinesterases (AChE and BChE) and monoamine oxidase MAO-B. It exhibits IC50 values of 0.24 µM for AChE, 6.29 µM for BChE, and 0.11 µM for MAO-B. AChE/BChE/MAO-B-IN-5 holds potential for research in neurodegenerative diseases such as Alzheimer's disease.</p>
    Fórmula:C22H14F3NO2
    Cor e Forma:Solid
    Peso molecular:381.347

    Ref: TM-T206229

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    LRRK2-IN-5

    <p>LRRK2-IN-5 is an oral, BBB-penetrating selective inhibitor for LRRK2 with IC50s: 1.2μM (GS) and 16μM (WT); halts LRRK2 autophosphorylation.</p>
    Fórmula:C24H26F2N4O2S
    Cor e Forma:Solid
    Peso molecular:472.55

    Ref: TM-T63057

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    SB 258741 hydrochloride

    <p>SB 258741 hydrochloride is a potent antagonist of the 5-HT 7 receptor, designed specifically for studying schizophrenia [1].</p>
    Fórmula:C19H31ClN2O2S
    Cor e Forma:Solid
    Peso molecular:386.98

    Ref: TM-T61724

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    AChE/BChE-IN-1

    <p>AChE/BChE-IN-1: dual AChE/BChE inhibitor, IC50 of 1.06 nM/7.3 nM, crosses blood-brain barrier, with antioxidant properties for Alzheimer's research.</p>
    Fórmula:C32H35ClN6O3
    Cor e Forma:Solid
    Peso molecular:587.11

    Ref: TM-T64156

  • (9R)-RO7185876
    Targetmol
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    (9R)-RO7185876

    CAS:
    <p>(9R)-RO7185876 (Compound example 16) is a γ-secretase inhibitor. It reduces the secretion of Αβ42. This compound can be employed in the research of Alzheimer's disease, cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, multi-infarct dementia, senile dementia, or Down syndrome.</p>
    Fórmula:C25H28F3N7
    Cor e Forma:Solid
    Peso molecular:483.532

    Ref: TM-T204358

  • BACE1-IN-2
    Targetmol
    + Info

    BACE1-IN-2

    CAS:
    <p>BACE1-IN-2 is a BACE1 inhibitor (IC50: 22 nM).</p>
    Fórmula:C19H15F4N5O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:421.35

    Ref: TM-T10451

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    (+)-Sparteine sulfate pentahydrate

    <p>(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.</p>
    Fórmula:C15H38N2O9S
    Cor e Forma:Solid
    Peso molecular:422.54

    Ref: TM-T62265

  • PF-06751979
    Targetmol
    + Info

    PF-06751979

    CAS:
    <p>PF-06751979 is an inhibitor of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) (IC50 of 7.3 nM in BACE1 binding assay).</p>
    Fórmula:C18H19F2N5O3S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:455.5

    Ref: TM-T12429

  • LRRK2-IN-4
    Targetmol
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    LRRK2-IN-4

    CAS:
    <p>LRRK2-IN-4: Potent, selective LRRK2 inhibitor, oral, BBB-penetrating, IC50=2.6 nM, potential for Parkinson's.</p>
    Fórmula:C25H29ClF2N6O2
    Cor e Forma:Solid
    Peso molecular:518.99

    Ref: TM-T63621

  • Gabaculine HCl
    Targetmol
    + Info

    Gabaculine HCl

    CAS:
    <p>Gabaculine, an irreversible GABA-T inhibitor (Ki: 2.9 μM), impacts plastid development and affects DPOR/GluTR levels.</p>
    Fórmula:C7H10ClNO2
    Cor e Forma:Solid
    Peso molecular:175.61

    Ref: TM-T24080

  • SEP-363856 mesylate
    Targetmol
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    SEP-363856 mesylate

    CAS:
    <p>SEP-363856 (SEP-856) mesylate is an orally active compound that acts as an agonist for both TAAR1 and 5-HT1A receptors. This compound exhibits antipsychotic activity in the central nervous system and has potential for the study of schizophrenia.</p>
    Fórmula:C10H17NO4S2
    Cor e Forma:Solid
    Peso molecular:279.38

    Ref: TM-T201258

  • Rodatristat ethyl
    Targetmol
    + Info

    Rodatristat ethyl

    CAS:
    <p>Rodatristat ethyl is an oral TPH1 inhibitor reducing 5-HT levels &amp; lowering PAH at low doses.</p>
    Fórmula:C29H31ClF3N5O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:590.04

    Ref: TM-T16779

  • RTIOXA-43
    Targetmol
    + Info

    RTIOXA-43

    CAS:
    <p>RTIOXA-43 is an OX2R/OX1R (orexin receptor) dual agonist that increases wakefulnesand is commonly used in studies related to narcolepsy and neural signaling.</p>
    Fórmula:C37H37N5O5S
    Pureza:99.17%
    Cor e Forma:Solid
    Peso molecular:663.79

    Ref: TM-T87345

  • BACE1-IN-5
    Targetmol
    + Info

    BACE1-IN-5

    CAS:
    <p>BACE1-IN-5 inhibits BACE1 (IC50: 9.1 nM) &amp; Aβ production (IC50: 0.82 nM), enhances hERG inhibition &amp; P-gp efflux.</p>
    Fórmula:C18H16F5N5O2S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:461.41

    Ref: TM-T10453

  • Nafimidone hydrochloride
    Targetmol
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    Nafimidone hydrochloride

    CAS:
    <p>Nafimidone hydrochloride, an antiepileptic agent, inhibits acetylcholinesterase, protects neurons, and ameliorates cognitive decline. It is utilized in epilepsy research.</p>
    Fórmula:C15H13ClN2O
    Cor e Forma:Solid
    Peso molecular:272.73

    Ref: TM-T201733

  • DA-8031
    Targetmol
    + Info

    DA-8031

    CAS:
    <p>DA-8031 is a selective and orally active serotonin reuptake inhibitor. It is utilized in research related to premature ejaculation (PE).</p>
    Fórmula:C21H24N2O2
    Cor e Forma:Solid
    Peso molecular:336.43

    Ref: TM-T201663

  • Sulamserod hydrochloride
    Targetmol
    + Info

    Sulamserod hydrochloride

    CAS:
    <p>Sulamserod hydrochloride is a 5-HT4 receptor antagonist. It is utilized in research related to gastrointestinal disorders.</p>
    Fórmula:C19H29Cl2N3O5S
    Cor e Forma:Solid
    Peso molecular:482.42

    Ref: TM-T201756