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Neurociência

Neurociência

Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.

Subcategorias de "Neurociência"

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Foram encontrados 5400 produtos de "Neurociência"

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  • MAO-B-IN-3


    <p>MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a Ki</p>
    Fórmula:C24H25N3O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:387.47
  • Maesopsin


    <p>Maesopsin is a useful organic compound for research related to life sciences and the catalog number is T124581.</p>
    Fórmula:C15H12O6
    Cor e Forma:Solid
    Peso molecular:288.255
  • Ebiratide TFA


    <p>Ebiratide (HOE-427) TFA is a derivative of ACTH4-9 that exerts its effect directly on the central nervous system, enhancing memory. Ebiratide TFA also promotes the metabolism of acetylcholine (ACh) in the rat brain.</p>
    Fórmula:C48H73N11O10S·xC2HF3O2
    Cor e Forma:Solid
    Peso molecular:996.23 (free base)
  • BSBM6

    CAS:
    <p>BSBM6 is an inhibitor of Aβ aggregation and neuronal toxicity that acts by reversing the aggregation and toxicity of amyloid-β peptides.</p>
    Fórmula:C23H29N3O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:427.49
  • (Iso)-Samixogrel

    CAS:
    <p>(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.</p>
    Fórmula:C25H25ClN2O4S
    Pureza:98.80%
    Cor e Forma:Solid
    Peso molecular:484.99
  • MAO-B-IN-18


    <p>MAO-B-IN-18 is a potent, selective inhibitor of MAO B, demonstrating IC50 values of 52 nM for hMAO B and 14 μM for hMAO A.</p>
    Fórmula:C25H22N4O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:458.47
  • Adatanserin hydrochloride

    CAS:
    <p>Adatanserin hydrochloride (WY50324 hydrochloride) is a 5-HT(1A)/5-HT(2) receptor ligand that is neuroprotective and may be used in the study of depression.</p>
    Fórmula:C21H32ClN5O
    Pureza:99.64%
    Cor e Forma:Solid
    Peso molecular:405.96
  • 5-HT6 agonist 1


    Compound 19, a 5-HT6 agonist with an affinity (K i : 5 nM), exhibits antidepressant-like effects and enhances cognitive function while also inhibiting platelet
    Fórmula:C17H22Cl2N6S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:413.37
  • AZD4694 Precursor

    CAS:
    <p>AZD4694 Precursor used for synthesizing [18F]AZD4694, a high-affinity amyloid-β imaging agent.</p>
    Fórmula:C22H25N3O7
    Cor e Forma:Solid
    Peso molecular:443.45
  • Oxotremorine

    CAS:
    <p>Oxotremorine acts as an agonist of mAChR, specifically activating the M1 and M3 acetylcholine receptors. In drug discrimination experiments with macaques, it exhibits effects similar to nicotine.</p>
    Fórmula:C12H18N2O
    Cor e Forma:Solid
    Peso molecular:206.28
  • 2-APB hydrochloride

    CAS:
    <p>2-APB is an analog of 6-APB and falls under the category of benzofuran derivatives, known for its psychoactive properties. Certain benzofuran derivatives also exhibit monoamine oxidase-A (MAO-A) inhibitory activity.</p>
    Fórmula:C11H14ClNO
    Cor e Forma:Solid
    Peso molecular:211.69
  • Melatonin-Tamoxifen Conjugate


    <p>Melatonin-Tamoxifen Conjugate (compound 16c) is an anticancer drug conjugate made of Melatonin and Tamoxifen, serving as an effective antagonist of ERα (IC50 = 863 nM). In cells expressing the hMT1 receptor, it binds to MLT receptors (Ki = 3.1 nM) and exhibits the ability to promote β-arrestin activation (EC50 = 914 nM) and ERK activation (EC50 = 98 nM). The IC50 values for Melatonin-Tamoxifen Conjugate in MCF-7, MDA-MB-231, and HT-1080 cell lines are 6.8 μM, 6.4 μM, and 1.7 μM, respectively.</p>
    Fórmula:C47H58N4O4
    Cor e Forma:Solid
    Peso molecular:742.99
  • Glycerophosphorylethanolamine (sodium salt)

    CAS:
    <p>Glycerophosphorylethanolamine, a phosphatidylethanolamine metabolite, elevates in Alzheimer's and promotes Aβ40 aggregation.</p>
    Fórmula:C5H13NNaO6P
    Cor e Forma:Solid
    Peso molecular:237.12
  • Fentonium bromide

    CAS:
    <p>Fentonium bromide is a biochemical.</p>
    Fórmula:C31H34BrNO4
    Cor e Forma:Solid
    Peso molecular:564.51
  • BMS-906024

    CAS:
    <p>BMS-906024 (Osugacestat) is a gamma secretase inhibitor, a Notch inhibitor.BMS-906024 has broad-spectrum antitumour activity.</p>
    Fórmula:C26H26F6N4O3
    Pureza:99.88% - >99.99%
    Cor e Forma:Solid
    Peso molecular:556.5
  • (+)-Coclaurine hydrochloride

    CAS:
    <p>(+)-Coclaurine hydrochloride, also known as (+)-(R)-Coclaurine, is a benzyltetrahydroisoquinoline alkaloid extracted from multiple plant species.</p>
    Fórmula:C17H20ClNO3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:321.8
  • FGIN-1-43

    CAS:
    <p>FGIN-1-43 is a potent and specific ligand for the mitochondrial DBI receptor.</p>
    Fórmula:C28H36Cl2N2O
    Pureza:99.57%
    Cor e Forma:Solid
    Peso molecular:487.5
  • (Iso)-Atagabalin HCl

    CAS:
    <p>(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.</p>
    Fórmula:C10H20ClNO2
    Pureza:99.26% - >99.99%
    Cor e Forma:Soild
    Peso molecular:221.72
  • [D-Trp7,9,10]-Substance P

    CAS:
    <p>Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.</p>
    Fórmula:C79H105N21O13S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1588.89
  • Crenezumab

    CAS:
    <p>Crenezumab (MABT 5102A) is a fully humanized anti-amyloid-beta antibody that binds to multiple forms of amyloid-beta (Aβ) for the study of Alzheimer's disease.</p>
    Pureza:97.5% (SDS-PAGE); 95.3% (SEC-HPLC) - 97.5% (SDS-PAGE); 95.3% (SEC-HPLC)
    Cor e Forma:Liquid