Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(942 produtos)
- ACK(1 produtos)
- AChR(575 produtos)
- ATP Citrato Liase(16 produtos)
- Receptor adrenérgico(2.946 produtos)
- BACE(36 produtos)
- Beta Amilóide(205 produtos)
- CaMK(69 produtos)
- COX(562 produtos)
- Receptor de Dopamina(408 produtos)
- Receptor GABA(336 produtos)
- Gama-secretase(59 produtos)
- GluR(255 produtos)
- GlyT(24 produtos)
- Receptor de Histamina(359 produtos)
- LRRK2(33 produtos)
- Receptor de Melatonina(24 produtos)
- NMDAR(28 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5400 produtos de "Neurociência"
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HTR2A antagonist 1
<p>HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.</p>Fórmula:C35H43Cl2F2N5O4Cor e Forma:SolidPeso molecular:706.65SB 699551
CAS:<p>SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.</p>Fórmula:C34H45N3OPureza:99.83%Peso molecular:511.74AChE-IN-4
<p>AChE-IN-4 is an acetylcholine esterase inhibitor (AChEI) with an IC50 value of 24.1 μM.</p>Fórmula:C32H25BrN6O4SCor e Forma:SolidPeso molecular:669.555-methoxy-α-Ethyltryptamine
CAS:<p>5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects. </p>Fórmula:C13H18N2OPureza:98.25%Cor e Forma:SolidPeso molecular:218.29AChE/BChE-IN-26
<p>AChE/BChE-IN-26 (Compound 20aa) is a cholinesterase inhibitor with IC50 values of 0.75 μM for eeAChE and 4.11 μM for eqBChE. This compound possesses antioxidant properties and is applicable in research related to diseases such as Alzheimer's.</p>Cor e Forma:Odour SolidmcK6A1
<p>mcK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.</p>Fórmula:C71H99N17O16Cor e Forma:SolidPeso molecular:1446.65Alosetron-d3
CAS:<p>Alosetron D3 (GR 68755 D3) is a deuterium-labeled Alosetron. Alosetron is an antagonist of 5HT3-receptor.</p>Fórmula:C17H18N4OPureza:98%Cor e Forma:SolidPeso molecular:297.37Alosetron
CAS:<p>Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.</p>Fórmula:C17H18N4OPureza:98%Cor e Forma:Crystalline PowderPeso molecular:294.36NMDA receptor antagonist 8
<p>Compound (R)-10a, an NMDA receptor antagonist, exhibits selectivity for the GluN2B subunit, possessing a Ki of 265 nM and an IC50 of 62 nM.</p>Fórmula:C22H27N3OPureza:98%Cor e Forma:SolidPeso molecular:349.47β-Secretase Inhibitor II
CAS:<p>β-Secretase Inhibitor II is a tripeptide aldehyde compound that acts as an inhibitor of β-Secretase.</p>Fórmula:C25H39N3O5Cor e Forma:SolidPeso molecular:461.59Profenofos
CAS:<p>Profenofos is an organophosphate insecticide used in cotton and vegetables. that causes neurotoxicity through the inhibition of AChE activity.</p>Fórmula:C11H15BrClO3PSPureza:97.04% - 97.24%Cor e Forma:SolidPeso molecular:373.63SKF-83566 hydrochloride
CAS:<p>SKF-83566 hydrochloride is a D1-like dopamine receptor antagonist, inhibiting dopamine transporters and mitigating GBP-induced CPP.</p>Fórmula:C17H19BrClNOPureza:99.27%Cor e Forma:SoildPeso molecular:368.69DOPR hydrochloride
CAS:<p>DOPR hydrochloride is a psychoactive substance belonging to the amphetamine class.</p>Fórmula:C14H24ClNO2Cor e Forma:SolidPeso molecular:273.84-Bromo-2,5-DMMA
CAS:<p>4-Bromo-2,5-DMMA (Compound 2) demonstrates affinity for the 5-HT2 binding site and has an ED50 of 0.82 mg/kg in rat discrimination experiments.</p>Fórmula:C12H18BrNO2Cor e Forma:SolidPeso molecular:288.18Desalkylgidazepam
CAS:<p>Desalkylgidazepam, a benzodiazepine compound, is a metabolite of gidazepam. It is capable of activating both GABA A-type receptors and the translocator protein (TSPO).</p>Fórmula:C15H11BrN2OCor e Forma:SolidPeso molecular:315.17Nipecotic acid
CAS:<p>Compound PDK0243, with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0243 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C6H11NO2Cor e Forma:Off-White To Pale Yellow-Beige PowderPeso molecular:129.1625N-NBOMe hydrochloride
CAS:<p>25N-NBOMe hydrochloride is a derivative of 2C-N and acts as an agonist for the 5-HT2A and 5-HT2C receptors, with Ki values of 0.144 nM and 1.06 nM, respectively. It has minimal effect on the release of preloaded neurotransmitters from recombinant dopamine, serotonin, and norepinephrine transporters.</p>Fórmula:C18H23ClN2O5Cor e Forma:SolidPeso molecular:382.84PSEN1-IN-2
<p>PSEN1-IN-2 (Compound 13K) is a potent inhibitor of both PSEN1-APH1A and PSEN1-APH1B complexes, exhibiting IC50 values of 6.9 nM and 2.4 nM, respectively.</p>Fórmula:C20H18ClFN2O3SCor e Forma:SolidPeso molecular:420.885-MeO-MET
CAS:<p>5-MeO-MET (5-Methoxy-N-methyl-N-ethyltryptamine) is a compound belonging to the 5-methoxytryptamine class. It acts as an agonist for 5-HT1A and 5-HT2A receptors. In mice, 5-MeO-MET inhibits locomotion and has sedative effects.</p>Fórmula:C14H20N2OCor e Forma:SolidPeso molecular:232.32Pyrantel hydrochloride
CAS:<p>Pyrantel hydrochloride is the hydrochloride form of Pyrantel. Pyrantel is is an anthelmintic and a nicotinic acetylcholine receptor (nAChR) agonist.</p>Fórmula:C11H15ClN2SPureza:98.01%Cor e Forma:SoildPeso molecular:242.77
