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Neurociência

Neurociência

Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.

Subcategorias de "Neurociência"

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Foram encontrados 5389 produtos de "Neurociência"

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  • Logotipo do CymitQuimica
    Targetmol
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    AChE/BChE-IN-14

    <p>AChE/BChE-IN-14 (compound 13), a benzylisoquinoline alkaloid extracted from Fissistigma polyanthum roots, demonstrates inhibitory effects on both</p>
    Fórmula:C19H23NO3
    Cor e Forma:Solid
    Peso molecular:313.39

    Ref: TM-T79966

  • β-Amyloid (1-34)
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    β-Amyloid (1-34)

    CAS:
    <p>This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.</p>
    Fórmula:C170H253N47O52
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3787.2

    Ref: TM-TP1599

  • LRRK2 inhibitor 1
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    LRRK2 inhibitor 1

    CAS:
    <p>LRRK2 inhibitor 1 is a selective and potent LRRK2 inhibitor with an IC50 of 13 nM.LRRK2 inhibitor 1 inhibits DCLK1 kinase with an IC50 value of 2.61 nM.</p>
    Fórmula:C20H23N5O4
    Pureza:99.94%
    Cor e Forma:Solid
    Peso molecular:397.43

    Ref: TM-T11878

  • Logotipo do CymitQuimica
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    AChE-IN-45

    <p>AChE-IN-45 (Compound 14) is an acetylcholinesterase (AChE) inhibitor exhibiting an IC50 value of 11.57±0.45 nM, and it demonstrates both antioxidant and</p>
    Cor e Forma:Odour Solid

    Ref: TM-T83183

  • Logotipo do CymitQuimica
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    AChE/Aβ-IN-6

    <p>BACE1-IN-15 (compound 4j) serves as an effective inhibitor of BACE1 (β-secretase), efficiently mitigating the copper-induced toxicity of Aβ, with an EC50 value of 0.68 μM.</p>
    Cor e Forma:Odour Solid

    Ref: TM-T89221

  • 4-P-PDOT
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    4-P-PDOT

    CAS:
    <p>4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.</p>
    Fórmula:C19H21NO
    Pureza:99.91%
    Cor e Forma:Solid
    Peso molecular:279.38

    Ref: TM-T14042

  • Triazolomethylindole-3-acetic acid
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    Triazolomethylindole-3-acetic acid

    CAS:
    <p>Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.</p>
    Fórmula:C13H12N4O2
    Cor e Forma:Solid
    Peso molecular:256.26

    Ref: TM-T203624

  • Cevimeline hydrochloride hemihydrate
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    Cevimeline hydrochloride hemihydrate

    CAS:
    <p>Cevimeline hydrochloride hemihydrate is a novel muscarinic receptor agonist, used as a candidate therapeutic drug for xerostomia in Sjogren's syndrome.</p>
    Fórmula:C20H38Cl2N2O3S2
    Pureza:97.00%
    Cor e Forma:Solid
    Peso molecular:489.55

    Ref: TM-T2390

  • CGP 35348
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    CGP 35348

    CAS:
    <p>CGP 35348 是 GABAB 受体的选择性拮抗剂 (EC50 = 34 μM)。 CGP 35348 可用于研究白化新生小鼠脑损伤后的神经肌肉协调和空间学习。</p>
    Fórmula:C8H20NO4P
    Pureza:≥98%
    Cor e Forma:Solid
    Peso molecular:225.22

    Ref: TM-T21793

  • Logotipo do CymitQuimica
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    GM-60186

    GM-60186, a potent inhibitor of the 5-HT receptor 2B (HTR2B) with an IC50 of 257 nM, effectively suppresses the proliferation and migration of colorectal cancer cells.
    Fórmula:C30H33FN2O4
    Cor e Forma:Solid
    Peso molecular:504.59

    Ref: TM-T201190

  • JH-XII-03-02
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    JH-XII-03-02

    CAS:
    <p>JH-XII-03-02 is a potent and selective leucine-rich repeat kinase 2 (LRRK2) proteolysis targeting chimera (PROTAC) degrader, utilized in Parkinson's Disease (PD</p>
    Fórmula:C43H51N9O10
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:853.92

    Ref: TM-T79351

  • AChE-IN-86
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    AChE-IN-86

    <p>AChE-IN-86 (Compound 6f) is an inhibitor of acetylcholinesterase (AChE) with an IC50 value of 25.33 μg/mL. This compound exerts its inhibitory effects by forming hydrogen bonds, π-π, and π-alkyl interactions with amino acid residues at the key catalytic site of AChE. AChE-IN-86 can be utilized in Alzheimer's disease research.</p>
    Fórmula:C28H27N3O6S
    Cor e Forma:Solid
    Peso molecular:533.595

    Ref: TM-T206075

  • TIP 39, Tuberoinfundibular Neuropeptide
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    TIP 39, Tuberoinfundibular Neuropeptide

    CAS:
    <p>TIP39 is a synthetic neuropeptide agonist for human and rat PTH2 receptors from the hypothalamus.</p>
    Fórmula:C202H325N61O54S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:4504.2

    Ref: TM-TP1688

  • LE 300
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    LE 300

    CAS:
    <p>LE 300 represents a structurally novel type of antagonists acting preferentially at the dopamine D(1)/D(5)receptors and the serotonin 5-HT(2A)receptor.</p>
    Fórmula:C20H22N2
    Pureza:97.91% - 98.79%
    Cor e Forma:Solid
    Peso molecular:290.4

    Ref: TM-T22921

  • Tryptamine hydrochloride
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    Tryptamine hydrochloride

    CAS:
    <p>Tryptamine hydrochloride is a monoamine alkaloid, metabolite of tryptophan and CNS active substance, agonist of 5-HT4 receptor, TAAR1, AHR.</p>
    Fórmula:C10H13ClN2
    Pureza:99.89%
    Cor e Forma:Solid
    Peso molecular:196.68

    Ref: TM-T124997

  • AC1-IN-1
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    AC1-IN-1

    CAS:
    <p>AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).</p>
    Fórmula:C18H18FN5O2
    Pureza:99.89%
    Cor e Forma:Solid
    Peso molecular:355.37

    Ref: TM-T60003

  • BChE-IN-10
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    BChE-IN-10

    CAS:
    <p>BChE-IN-10, a strong mixed BChE inhibitor (IC50=6.4 μM), comes from Bletilla striata for AD research.</p>
    Fórmula:C23H20O5
    Cor e Forma:Solid
    Peso molecular:376.4

    Ref: TM-T75511

  • 1,8-Cineole
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    1,8-Cineole

    CAS:
    <p>Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.</p>
    Fórmula:C10H18O
    Pureza:97.44% - 97.44%
    Cor e Forma:Solid
    Peso molecular:154.25

    Ref: TM-T1714

  • LY-53857 free base
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    LY-53857 free base

    CAS:
    <p>LY-53857 free base is a bioactive chemical.</p>
    Fórmula:C23H32N2O3
    Cor e Forma:Solid
    Peso molecular:384.51

    Ref: TM-T33018

  • (S,S)-BMS-984923
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    (S,S)-BMS-984923

    CAS:
    <p>(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 &gt;1μM; less active than its potent counterpart.</p>
    Fórmula:C22H15ClN2O2
    Cor e Forma:Solid
    Peso molecular:374.82

    Ref: TM-T74185