Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(940 produtos)
- ACK(1 produtos)
- AChR(574 produtos)
- ATP Citrato Liase(16 produtos)
- Receptor adrenérgico(2.939 produtos)
- BACE(36 produtos)
- Beta Amilóide(204 produtos)
- CaMK(68 produtos)
- COX(562 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor GABA(336 produtos)
- Gama-secretase(59 produtos)
- GluR(255 produtos)
- GlyT(24 produtos)
- Receptor de Histamina(358 produtos)
- LRRK2(33 produtos)
- Receptor de Melatonina(24 produtos)
- NMDAR(28 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(296 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5400 produtos de "Neurociência"
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Aβ-IN-7
<p>Aβ-IN-7 (compound 5a) acts as a potent inhibitor of Aβ aggregation, stabilizing Aβ monomers at 50 μM concentration to prevent them from forming larger oligomers</p>Fórmula:C14H10N2SCor e Forma:SolidPeso molecular:238.31Furosemide sodium
CAS:<p>Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.</p>Fórmula:C12H10ClN2NaO5SPureza:99.52% - >99.99%Cor e Forma:SolidPeso molecular:352.73Arisugacin G
CAS:<p>Arisugacin G, a microbial metabolite, is a structural analogue of Arisugacin A. Unlike its analogue, Arisugacin G does not exhibit activity against AChE (acetylcholinesterase).</p>Fórmula:C27H32O5Cor e Forma:SolidPeso molecular:436.544-Hydroxy MET
CAS:<p>4-Hydroxy MET (4-HO-MET) is a tryptamine-based new psychoactive substance (NPS), structurally similar to the endogenous neurotransmitter serotonin. It has hallucinogenic properties that affect mood, movement, and cognitive functions.</p>Fórmula:C13H18N2OCor e Forma:SolidPeso molecular:218.3Pellotine
CAS:<p>Pellotine is an alkaloid isolated from Lophophora. It acts as an inverse agonist of the 5-HT7 receptor (5-HT7 receptor), with an EC50 of 291 nM. Pellotine shows strong affinity for the 5-HT1DR and 5-HT6R, with Ki values of 117 nM and 170 nM, respectively. Additionally, Pellotine reduces intracellular cAMP levels, thereby decreasing neuronal excitability and neurotransmitter release.</p>Fórmula:C13H19NO3Cor e Forma:SolidPeso molecular:237.295BChE-IN-39
<p>BChE-IN-39 (Compound 7c) selectively inhibits butyrylcholinesterase (BChE) with an IC50 of 0.08 μM, while showing an IC50 of 3.98 μM for acetylcholinesterase (AChE) inhibition. Additionally, BChE-IN-39 downregulates GSK-3β expression, thereby inhibiting the excessive phosphorylation of tau protein.</p>Fórmula:C29H23ClFN3O3Cor e Forma:SolidPeso molecular:515.963Chrodrimanin B
CAS:<p>Chrodrimanin B is a useful organic compound for research related to life sciences. The catalog number is T126052 and the CAS number is 132196-54-4.</p>Fórmula:C27H32O8Cor e Forma:SolidPeso molecular:484.545NPS ALX Compound 4a hydrochloride(1:1)
<p>NPS ALX Compound 4a hydrochloride(1:1) is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.</p>Fórmula:C25H26ClN3O2SPureza:99.84%Cor e Forma:SoildPeso molecular:468.01LY 344864 racemate
CAS:<p>LY 344864 racemate is a 5-HT1F receptor agonist.</p>Fórmula:C21H22FN3OPureza:99.75%Cor e Forma:SoildPeso molecular:351.42Fipronil sulfone
CAS:<p>Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.</p>Fórmula:C12H4Cl2F6N4O2SPureza:98%Cor e Forma:SolidPeso molecular:453.1412,14-Dichlorodehydroabietic acid
CAS:<p>12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.</p>Fórmula:C20H26Cl2O2Cor e Forma:SolidPeso molecular:369.33Methyllycaconitine citrate
CAS:<p>Methyllycaconitine citrate (MLA) is an α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist that crosses the blood-brain barrier.</p>Fórmula:C43H58N2O17Pureza:98.03% - 98.91%Cor e Forma:SolidPeso molecular:874.92β-Amyloid (12-20)
CAS:<p>β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad has</p>Fórmula:C57H83N15O11Pureza:98%Cor e Forma:SolidPeso molecular:1154.36VVZ-149
<p>VVZ-149 is an antagonist of both serotonin receptor 2A (5HT2A) and glycine transporter type 2 (GlyT2), with potential anti-nociceptive activity.</p>Cor e Forma:SolidSerazapine
CAS:<p>Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.</p>Fórmula:C22H23N3O2Pureza:98.71% - 99.57%Cor e Forma:SolidPeso molecular:361.44Zalospirone
CAS:<p>Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder.</p>Fórmula:C24H29N5O2Pureza:98.41% - 99.82%Cor e Forma:SolidPeso molecular:419.52K1833
<p>K1833 is an inhibitor and reactivator of human acetylcholinesterase (hrAChE), exhibiting an inhibition concentration (IC50) of 58$.</p>Cor e Forma:Odour SolidEthylpropyltryptamine
CAS:<p>Ethylpropyltryptamine (EPT) is an orally active novel psychoactive substance. It is predicted to act as a partial agonist of the 5-HT2A receptor.</p>Fórmula:C15H22N2Cor e Forma:SolidPeso molecular:230.35Monoamine oxidase
CAS:<p>Enzyme that breaks down amines in the brain and body, affecting mood and brain function.</p>Cor e Forma:SolidRiluzole-13C,15N2
CAS:<p>Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.</p>Fórmula:CC7H5F3OS15N2Cor e Forma:SolidPeso molecular:237.18Azocarnil
<p>Azocarnil is a GABAergic agonist-enhancer used in neurological system research.</p>Cor e Forma:Odour SolidFFN246
CAS:<p>FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation and</p>Fórmula:C15H13FN2OPureza:98%Cor e Forma:SolidPeso molecular:256.27β-Secretase Inhibitor II
CAS:<p>β-Secretase Inhibitor II is a tripeptide aldehyde compound that acts as an inhibitor of β-Secretase.</p>Fórmula:C25H39N3O5Cor e Forma:SolidPeso molecular:461.59Epiboxidine hydrochloride
CAS:<p>Epiboxidine HCl: potent α4β2 nAChR agonist; Ki 0.46 nM (rat), 1.2 nM (human); Epibatidine analog.</p>Fórmula:C10H15ClN2OCor e Forma:SolidPeso molecular:214.69(rel)-Asperparaline A
CAS:<p>Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.</p>Fórmula:C20H29N3O3Cor e Forma:SolidPeso molecular:359.47Atracurium
CAS:<p>Atracurium (BW-33A) is a competitive AChR antagonist and non-depolarizing muscle relaxant that may cause bronchoconstriction.</p>Fórmula:C53H72N2O122Cor e Forma:SolidPeso molecular:929.14RAGE antagonist peptide
CAS:<p>RAGE antagonist blocks S100P/A4, HMGB-1; hinders glioma growth, metastasis; reduces PDAC cell growth, NF-κB activity; counters TDI effects in mice.</p>Fórmula:C57H101N13O17SPureza:98%Cor e Forma:SolidPeso molecular:1272.56Bensultap
CAS:<p>Bensultap is an agricultural chemical typically used as a pesticide.</p>Fórmula:C17H21NO4S4Pureza:98%Cor e Forma:SolidPeso molecular:431.61ECPLA
CAS:<p>ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.</p>Fórmula:C21H25N3OCor e Forma:SolidPeso molecular:335.44Bleformin A
CAS:<p>Bleformin A, a natural BChE inhibitor from Bletilla striata, has a 5.2 μM IC50 and is studied for Alzheimer's research.</p>Fórmula:C23H20O5Cor e Forma:SolidPeso molecular:376.4Osmanthuside B
CAS:<p>Osmanthuside B, isolated from Pseuderanthemum carruthersii (Seem.) Guill.</p>Fórmula:C29H36O13Cor e Forma:SolidPeso molecular:592.59α-Conotoxin AuIB
CAS:<p>Selective antagonist of α3β4 nicotinic acetylcholine receptors.</p>Fórmula:C65H89N17O21S4Pureza:98%Cor e Forma:SolidPeso molecular:1572.76β-Secretase Inhibitor I
CAS:<p>β-Secretase Inhibitor I is a highly potent inhibitor of the β-secretase enzyme.</p>Fórmula:C18H18F3N5O2SCor e Forma:SolidPeso molecular:425.43HDAC6-IN-49
<p>HDAC6-IN-49 (Compound 3) is an inhibitor of HDAC, with IC50 values of 0.012 and 0.735 µM against HDAC6 and HDAC1, respectively. Additionally, it inhibits MAO-B, cholinesterase (ChE), histamine receptor (H3R), and serotonin 6 receptor (5-HT6R). HDAC6-IN-49 exhibits neuroprotective effects in SH-SY5Y cells and enhances cognitive functions and motor abilities in fruit fly models of Parkinson's disease and C. elegans models of Alzheimer's disease.</p>Cor e Forma:Odour SolidAChE-IN-4
<p>AChE-IN-4 is an acetylcholine esterase inhibitor (AChEI) with an IC50 value of 24.1 μM.</p>Fórmula:C32H25BrN6O4SCor e Forma:SolidPeso molecular:669.55β-Amyloid (1-17)
CAS:<p>This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.</p>Fórmula:C90H130N28O29Pureza:98%Cor e Forma:SolidPeso molecular:2068.2ALEPH hydrochloride
CAS:<p>ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.</p>Fórmula:C12H20ClNO2SCor e Forma:SolidPeso molecular:277.81Mant-GTPγS
CAS:<p>Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.</p>Fórmula:C18H23N6O14P3SCor e Forma:SolidPeso molecular:672.39Antidepressant agent 3
<p>Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.</p>Fórmula:C17H30ClN5O2SCor e Forma:SolidPeso molecular:403.974-Butyl-α-agarofuran
CAS:<p>4-Butyl-alpha-agarofuran, a Gharu-wood derivative, is an anxiolytic, antidepressant, and aids neurological research.</p>Fórmula:C18H30OCor e Forma:SolidPeso molecular:262.43β-Amyloid (1-20)
CAS:<p>This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.</p>Fórmula:C113H157N31O32Pureza:98%Cor e Forma:SolidPeso molecular:2461.7Stacofylline
CAS:<p>Stacofylline is a xanthine derivative that is used to treat migraine headaches.</p>Fórmula:C20H33N7O3Pureza:99.54% - >99.99%Cor e Forma:SolidPeso molecular:419.52Velnacrine
CAS:<p>Velnacrine (1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate) is a biochemical.</p>Fórmula:C13H14N2OPureza:99.83%Cor e Forma:SolidPeso molecular:214.26GABAA receptor modulator-3
<p>GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.</p>Fórmula:C18H22O2Cor e Forma:SolidPeso molecular:270.37Dipentylone hydrochloride
CAS:<p>Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.</p>Fórmula:C14H20ClNO3Pureza:99.94%Cor e Forma:SolidPeso molecular:285.77Deoxynojirimycin Tetrabenzyl Ether
CAS:<p>Deoxynojirimycin tetrabenzyl ether aids in making 1-dNM, a strong α-glucosidase I & II blocker.</p>Fórmula:C34H37NO4Cor e Forma:SolidPeso molecular:523.673MAO-B-IN-38
<p>MAO-B-IN-38 (Compound 6b) is a reversible, competitive inhibitor of MAO-B, exhibiting IC50 values of 0.03 µM for MAO-B and 21.46 µM for MAO-A. This compound is applicable in research on neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.</p>Fórmula:C14H17FN4O2S3Cor e Forma:SolidPeso molecular:388.504Neocarzinostatin
CAS:<p>Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.</p>Pureza:98%Cor e Forma:SolidPeso molecular:N/A5-MeO-pyr-T
CAS:<p>5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.</p>Fórmula:C15H20N2OCor e Forma:SolidPeso molecular:244.33HTR2A antagonist 1
<p>HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.</p>Fórmula:C35H43Cl2F2N5O4Cor e Forma:SolidPeso molecular:706.65Biperiden Hydrochloride
CAS:<p>Biperiden HCl is an anti-Parkinson's drug, blocks M1 receptors, manages all Parkinson's types, and is FDA-approved. Non-toxic at 0.11 mg/kg to rats' cognition.</p>Fórmula:C21H30ClNOPureza:98%Cor e Forma:SolidPeso molecular:347.92Tiflucarbine
CAS:<p>Tiflucarbine is a potential non-selective 5-HT agonist with antidepressant activity.Tiflucarbine dose-dependently increased the specific activity of soluble</p>Fórmula:C16H17FN2SPureza:>99.99%Cor e Forma:SolidPeso molecular:288.38Alosetron-d3
CAS:<p>Alosetron D3 (GR 68755 D3) is a deuterium-labeled Alosetron. Alosetron is an antagonist of 5HT3-receptor.</p>Fórmula:C17H18N4OPureza:98%Cor e Forma:SolidPeso molecular:297.37COX-2-IN-49
<p>COX-2-IN-49 (compound 6c) is a potent inhibitor of cyclooxygenase-2 (COX-2), displaying an IC50 value of 2.671 µM. This compound exhibits anti-proliferative properties and holds potential for use in cancer research.</p>Cor e Forma:Odour SolidAChE/MAO-B-IN-7
<p>AChE/MAO-B-IN-7 (VAV-8) is a compound that acts as a dual inhibitor of acetylcholinesterase (AChE) and MAO-B, with the ability to cross the blood-brain barrier. It also inhibits the aggregation of Aβ42, making it a valuable compound for Alzheimer's disease (AD) research.</p>Fórmula:C22H21N3O3Cor e Forma:SolidPeso molecular:375.42Donitriptan hydrochloride
CAS:<p>Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively</p>Fórmula:C23H26ClN5O2Pureza:99.8% - 99.86%Cor e Forma:SolidPeso molecular:439.94bPiDDB
CAS:<p>bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.</p>Fórmula:C24H38Br2N2Pureza:98.72%Cor e Forma:SolidPeso molecular:514.38[Ala11,D-Leu15]-Orexin B(human)
CAS:<p>OX2 receptor agonist with 400x selectivity vs OX1. EC50: 0.13 nM (OX2), 52 nM (OX1).</p>Fórmula:C120H206N44O35SPureza:98%Cor e Forma:SolidPeso molecular:2857.28LY836
<p>LY836 is an orally active, neuroprotective compound that effectively inhibits the PSD95-nNOS association in cortical neurons.</p>Pureza:98%Cor e Forma:Odour SolidJNJ-67569762
CAS:<p>JNJ-67569762 is a selective BACE1 inhibitor targeting the S3 pocket ( IC 50 = 2.7 nM).</p>Fórmula:C22H22F4N4O5SCor e Forma:SolidPeso molecular:530.495-HT6R antagonist 1
<p>Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stability</p>Fórmula:C17H22F2N6OPureza:98%Cor e Forma:SolidPeso molecular:364.39R-(+)-Cotinine
CAS:<p>R-(+)-Cotinine, an inactive nicotine metabolite, boosts Ach-induced current in human α7 nAChRs.</p>Fórmula:C10H12N2OCor e Forma:SolidPeso molecular:176.22GABAA receptor modulator-4
<p>GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.</p>Fórmula:C15H17BrO4SCor e Forma:SolidPeso molecular:373.26AC3-I, myristoylated
<p>Myristoylated AC3-I is a biologically active peptide and a myristoylated variant of the Autocamtide-3-Derived Inhibitory Peptide (AC3-I).</p>Fórmula:C78H137N21O20Pureza:98%Cor e Forma:SolidPeso molecular:1689.05Exosome Compound Library
<p>76 exosome-related compounds that can be used for high-throughput and high-content screening.</p>Cor e Forma:Odour SolidGAD65(247-266) epitope TFA
<p>GAD65(247-266) epitope TFA, a T cell epitope derived from islet antigens, exhibits competitive binding to the type I diabetes-associated molecule I-A g7, albeit</p>Fórmula:C111H174F3N27O29S4Pureza:98%Cor e Forma:SolidPeso molecular:2535.99COX-1/2-IN-5
<p>COX-1/2-IN-5 (compound 2a) functions as a dual inhibitor of COX1/2, demonstrating inhibitory concentrations (IC50) of 2.650 μM and 0.958 μM, respectively, and</p>Fórmula:C21H22N2O5SPureza:98%Cor e Forma:SolidPeso molecular:414.47COX-2-IN-33
<p>COX-2-IN-33 (compound 5f) is a selective COX-2 inhibitor with an IC50 value of 45.5 nM and exhibits potential as an anti-inflammatory agent.</p>Fórmula:C20H13ClF3N5O4Pureza:98%Cor e Forma:SolidPeso molecular:479.8CaMKIIα-PHOTAC
<p>CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα).</p>Fórmula:C54H58Cl2N10O11Pureza:98%Cor e Forma:SolidPeso molecular:1094β-Amyloid (1-34)
CAS:<p>This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.</p>Fórmula:C170H253N47O52Pureza:98%Cor e Forma:SolidPeso molecular:3787.2IHC3
<p>IHC3 is a competitive and reversible monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.672 μM, which targets Cys172 within the enzyme's active site.</p>Fórmula:C17H12FN3OPureza:98%Cor e Forma:SolidPeso molecular:293.3N-Methylcyclohexaneethaneamine
CAS:<p>N-Methylcyclohexaneethaneamine is a useful organic compound for research related to life sciences.</p>Fórmula:C9H19NCor e Forma:SolidPeso molecular:141.2539Methyl piperate
CAS:<p>Methylpiperic acid, a piperine alkaloid, exhibits potent inhibitory activity on monoamine oxidase (MAO), with differing efficacy on isoforms: greater inhibition</p>Fórmula:C13H12O4Pureza:98%Cor e Forma:SolidPeso molecular:232.23MmTx1 toxin
<p>Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor's sensitivity to its agonist [1].</p>Fórmula:C295H455N95O97S10Pureza:98%Cor e Forma:SolidPeso molecular:7205PF-03382792
CAS:<p>PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.</p>Fórmula:C23H32FN3O4Pureza:99.64%Cor e Forma:SolidPeso molecular:433.52Isonaringin
CAS:<p>Isonaringin shows anti-Alzheimer’s activity by inhibiting AChE.</p>Fórmula:C27H32O14Cor e Forma:SolidPeso molecular:580.53Soclenicant
CAS:<p>Soclenicant is a negative-altering modulator of α 7 -nAChR for anxiety, depression, and PTSD, due to its high selectivity, oral availability</p>Fórmula:C24H26N4O3Pureza:99.57%Cor e Forma:SoildPeso molecular:418.49GABA receptor Antagonist 1
<p>GABA receptor Antagonist 1 (compound 7w) effectively inhibits the Px RDL1 GABAR at an IC50 of 7.08 nmol/L and demonstrates insecticidal efficacy against P.</p>Pureza:98%Cor e Forma:Odour Solid5-HT5AR/5-HT6R ligand-1
<p>5-HT5AR/5-HT6R ligand-1 (Compound PP10) is a ligand for serotonin receptors, exhibiting high affinity for the 5-HT5A and 5-HT6 receptors with Ki values of 59 nM and 96 nM, respectively. It possesses some antiproliferative activity against tumor cells and can be utilized in cancer research.</p>Fórmula:C25H30N4O2SCor e Forma:SolidPeso molecular:450.6Potassium Channel Targeted Library
<p>A unique collection of xnum potassium channel blockers and agonists for high throughput and high content screening;</p>Cor e Forma:Odour SolidCP 465022
CAS:<p>CP 465022 hydrochloride is a potent AMPA receptor antagonist with anti-seizure properties, inhibiting responses at an IC50 of 25 nM.</p>Fórmula:C26H24ClFN4OPureza:99.05%Cor e Forma:SolidPeso molecular:462.955-HT6R antagonist 6
<p>5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.</p>Fórmula:C24H26N4O2SCor e Forma:SolidPeso molecular:434.55MAOA-IN-1
<p>MAOA-IN-1 (compound 15) is an orally-active inhibitor of monoamine oxidase A (MAOA) that exhibits cytotoxic effects on prostate cancer cells.</p>Fórmula:C13H16Cl2N2O2Pureza:98%Cor e Forma:SolidPeso molecular:303.18JPC0323
<p>JPC0323 is a dual positive allosteric modulator of the 5-HT2C and 5-HT2A receptors, featuring on-target properties, acceptable plasma exposure, and adequate</p>Fórmula:C22H43NO4Pureza:98%Cor e Forma:SolidPeso molecular:385.58Bis-(-)-8-demethylmaritidine
<p>Bis-(-)-8-demethylmaritidine, a natural alkaloid, serves as a potent inhibitor of acetylcholinesterase (AChE) and is utilized in Alzheimer's disease research [1</p>Cor e Forma:Odour SolidAnti-inflammatory agent 53
<p>Anti-inflammatory agent 52 (compound 7c) is an orally active, selective COX-2 inhibitor with demonstrated anti-HT29 metastatic activity, causing periodic arrest</p>Fórmula:C24H22N2O4SPureza:98%Cor e Forma:SolidPeso molecular:434.51Histamine & Melatonin Receptor-Targeted Compound Library
<p>A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS</p>Cor e Forma:Odour SolidFezolamine
CAS:<p>Fezolamine: a new, non-tricyclic, oral antidepressant, selectively inhibits norepinephrine uptake over serotonin or dopamine.</p>Fórmula:C20H23N3Pureza:99.33%Cor e Forma:SolidPeso molecular:305.42Tranylcypromine
CAS:<p>Tranylcypromine (SKF 385), a potent monoamine oxidase (MAO) inhibitor [1], is used in medicinal applications.</p>Fórmula:C9H11NPureza:98%Cor e Forma:SolidPeso molecular:133.19hAChE-IN-3
<p>hAChE-IN-3 (compound 5c) serves as a potent inhibitor for AChE, BuChE, MAO-B, and BACE-1, with respective IC50 values of 0.44, 0.08, 5.15, and 0.38 μM,</p>Fórmula:C30H24ClN3O5Pureza:98%Cor e Forma:SolidPeso molecular:541.98Neurotransmitter Receptor Compound Library
<p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；</p>Cor e Forma:Odour SolidDCCCyb
CAS:<p>DCCCyb: oral GlyT1 inhibitor with high in vivo occupancy in rhesus monkeys, confirmed by PET tracer displacement.</p>Fórmula:C22H29Cl2NO3SPureza:98%Cor e Forma:SolidPeso molecular:458.44COX-2-IN-35
<p>COX-2-IN-35 (compound 7) is a selective inhibitor of COX-2, demonstrating anti-inflammatory activity, with an inhibitory concentration (IC 50) of 4.37 nM [1].</p>Fórmula:C22H19NO2S2Pureza:98%Cor e Forma:SolidPeso molecular:393.52MAO-B-IN-24
<p>MAO-B-IN-24 (compound 11h) is a selective, reversible, competitive inhibitor of MAO-B with an IC50 value of 1.60 μM.</p>Fórmula:C20H18N2OPureza:98%Cor e Forma:SolidPeso molecular:302.371,8-Cineole
CAS:<p>Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.</p>Fórmula:C10H18OPureza:97.44% - 97.44%Cor e Forma:SolidPeso molecular:154.25Serotonin Receptor-Targeted Compound Library
<p>A unique collection of xnum compounds targeting serotonin receptors for high throughput screening and high content screening;</p>Cor e Forma:Odour SolidIon Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Cor e Forma:Odour SolidCalcium Channel Compound Library
<p>A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;</p>Cor e Forma:Odour SolidPolyglutamine binding peptide 1
CAS:<p>Polyglutamine binding peptide 1 (QBP1) is a peptide inhibitor of polyglutamine (polyQ). It effectively inhibits polyQ protein aggregation in vitro and prevents polyQ-induced cell death in cell cultures.</p>Fórmula:C72H90N16O16Cor e Forma:SolidPeso molecular:1435.58CNS-Penetrant Compound Library
<p>A unique collection of 509 CNS-Penetrant compounds for high throughput screening (HTS) and high content screening (HCS);</p>Cor e Forma:Odour SolidTC-2216
CAS:<p>TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.</p>Fórmula:C12H17N3Pureza:99.33%Cor e Forma:SolidPeso molecular:203.28Flupyradifurone
CAS:<p>Flupyradifurone (flupyradifurone) is a systemic insecticide and nicotinic acetylcholine receptor (nAChR) agonist interfer nervous system of insects.</p>Fórmula:C12H11ClF2N2O2Pureza:99.83%Cor e Forma:SolidPeso molecular:288.68Neural Regeneration Compound Library
<p>A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening;</p>Cor e Forma:Odour SolidAL 34662
CAS:<p>AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also a</p>Fórmula:C10H13N3OPureza:99.77%Cor e Forma:SolidPeso molecular:191.23Hamaline
CAS:<p>Hamaline (9-(4-chlorobenzyl)-6-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole) is a substrate-selective cyclooxygenase-2 (COX-2) inhibitor.</p>Fórmula:C20H19ClN2OPureza:99.88%Cor e Forma:SoildPeso molecular:338.83DOPR hydrochloride
CAS:<p>DOPR hydrochloride is a psychoactive substance belonging to the amphetamine class.</p>Fórmula:C14H24ClNO2Cor e Forma:SolidPeso molecular:273.8Cinazepam
CAS:<p>Cinazepam is a GABAA receptor partial agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders.</p>Fórmula:C19H14BrClN2O5Cor e Forma:SolidPeso molecular:465.68Desalkylgidazepam
CAS:<p>Desalkylgidazepam, a benzodiazepine compound, is a metabolite of gidazepam. It is capable of activating both GABA A-type receptors and the translocator protein (TSPO).</p>Fórmula:C15H11BrN2OCor e Forma:SolidPeso molecular:315.174-Bromo-2,5-DMMA
CAS:<p>4-Bromo-2,5-DMMA (Compound 2) demonstrates affinity for the 5-HT2 binding site and has an ED50 of 0.82 mg/kg in rat discrimination experiments.</p>Fórmula:C12H18BrNO2Cor e Forma:SolidPeso molecular:288.18Minesapride
CAS:<p>Minesapride: novel 5-HT4 partial agonist, may treat constipation-predominant IBS.</p>Fórmula:C21H31ClN4O5Pureza:99.85% - 99.88%Cor e Forma:SolidPeso molecular:454.95Apoptosis Compound Library
<p>A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;</p>Cor e Forma:Odour SolidP-gb-IN-1
CAS:<p>P-gb-IN-1 is a potent P-glycoprotein (P-gp) inhibitor that exhibits reverse activity by inhibiting P-gp outflow.</p>Fórmula:C30H28N2O6Pureza:99.58%Cor e Forma:SoildPeso molecular:512.55p-Xylene bis(pyridinium bromide)
CAS:<p>p-Xylene bis(pyridinium bromide) (compound 21) is a cationic quenching agent and acts as a weak bis-quaternary ammonium salt inhibitor for AChE and BChE, with IC50 values of 1540 μM and 529 μM, respectively.</p>Fórmula:C18H18Br2N2Cor e Forma:SolidPeso molecular:422.16LY3020371
CAS:<p>LY3020371: potent, selective mGlu 2/3 receptor antagonist with Ki of 5.26 nM (hmGluR2) and 2.50 nM (hmGluR3); key in depression studies.</p>Fórmula:C15H15F2NO5SCor e Forma:SolidPeso molecular:359.34TET-13
<p>TET-13 is a positive allosteric modulator of the GABAA receptor with an EC50 of 5.65 μM, which is more potent than Etomidate (EC50: 9.29 μM). It exhibits strong anesthetic effects in both mice and rats, with an ED50 of 0.48 mg/kg in mice and 0.69 mg/kg in rats.</p>Fórmula:C15H16N2O3SCor e Forma:SolidPeso molecular:304.36(+)-OSU 6162
CAS:<p>(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.</p>Fórmula:C15H23NO2SPureza:98.19%Cor e Forma:SoildPeso molecular:281.41I2-IRs ligand-1
<p>I2-IRs ligand-1 (Compound 12d) is an orally active compound capable of crossing the blood-brain barrier. It exhibits high affinity for imidazoline I2 receptors (I2-IRs) with a pKi of 9.98. This compound can enhance cognitive deficits in aging mice and possesses analgesic, anti-inflammatory, and neuroprotective properties. I2-IRs ligand-1 is applicable for research in Alzheimer's disease and related pain disorders.</p>Fórmula:C21H23ClFN2O4PCor e Forma:SolidPeso molecular:452.84CVN417
<p>CVN417 is an orally active antagonist of nAChR containing the α6 subunit, modulating phasic dopaminergic neurotransmission in an impulse-dependent fashion.</p>Cor e Forma:Odour Solid1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS:<p>1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.</p>Fórmula:C10H12N2O2SPureza:99.96%Cor e Forma:SoildPeso molecular:224.28Aducanumab
CAS:<p>Aducanumab (BIIB037) is an IgG1 antibody targeting amyloid beta to treat Alzheimer's; it's brain-permeable.</p>Pureza:95% - 97.10%Cor e Forma:LiquidPeso molecular:145.93 kDaBIBD-124
CAS:<p>BIBD-124, with an IC50 value of 9.51 nM, effectively binds to amyloid beta (Aβ) plaques.</p>Fórmula:C19H24FN3O3Cor e Forma:SolidPeso molecular:361.41Pemedolac
CAS:<p>Pemedolac (Dexpemedolac) is a small molecule COX inhibitor used to treat neurological disorders, skin and musculoskeletal disorders.</p>Fórmula:C22H23NO3Pureza:>99.99%Cor e Forma:SolidPeso molecular:349.423-Aminopropylphosphonic Acid
CAS:<p>3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding</p>Fórmula:C3H10NO3PPureza:99.84%Cor e Forma:Light Yellow LiquidPeso molecular:139.09MK-0969
CAS:<p>MK-0969 (J-104135) is a possible M3 antagonist for the treatment of chronic obstructive pulmonary disease.</p>Fórmula:C24H30F2N4O2Cor e Forma:SolidPeso molecular:444.52CDD0102 HCl
CAS:<p>CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.</p>Fórmula:C8H13ClN4OPureza:99.7%Cor e Forma:SoildPeso molecular:216.6725N-NBOMe hydrochloride
CAS:<p>25N-NBOMe hydrochloride is a derivative of 2C-N and acts as an agonist for the 5-HT2A and 5-HT2C receptors, with Ki values of 0.144 nM and 1.06 nM, respectively. It has minimal effect on the release of preloaded neurotransmitters from recombinant dopamine, serotonin, and norepinephrine transporters.</p>Fórmula:C18H23ClN2O5Cor e Forma:SolidPeso molecular:382.84LtIA-F
<p>LtIA-F, a fluorescent LtIA derivative, aids study of α3β2 nAChR's structure, distribution, and binding domain.</p>Fórmula:C86H121N25O22S4Cor e Forma:SolidPeso molecular:1985.31Neuronal Signaling Compound Library
<p>A unique collection of xnum compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;</p>Cor e Forma:Odour SolidMelatonin-Tamoxifen Conjugate
<p>Melatonin-Tamoxifen Conjugate (compound 16c) is an anticancer drug conjugate made of Melatonin and Tamoxifen, serving as an effective antagonist of ERα (IC50 = 863 nM). In cells expressing the hMT1 receptor, it binds to MLT receptors (Ki = 3.1 nM) and exhibits the ability to promote β-arrestin activation (EC50 = 914 nM) and ERK activation (EC50 = 98 nM). The IC50 values for Melatonin-Tamoxifen Conjugate in MCF-7, MDA-MB-231, and HT-1080 cell lines are 6.8 μM, 6.4 μM, and 1.7 μM, respectively.</p>Fórmula:C47H58N4O4Cor e Forma:SolidPeso molecular:742.99Methalthiazide
CAS:<p>Methalthiazide enhances the activity of natural agonists of AMPA receptors and can be utilized in schizophrenia research.</p>Fórmula:C12H16ClN3O4S3Cor e Forma:SolidPeso molecular:397.92β-Amyloid (22-40)
CAS:<p>This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein.</p>Fórmula:C78H135N21O26SPureza:98%Cor e Forma:SolidPeso molecular:1815.12-APB hydrochloride
CAS:<p>2-APB is an analog of 6-APB and falls under the category of benzofuran derivatives, known for its psychoactive properties. Certain benzofuran derivatives also exhibit monoamine oxidase-A (MAO-A) inhibitory activity.</p>Fórmula:C11H14ClNOCor e Forma:SolidPeso molecular:211.69Rilmazolam
CAS:<p>Rilmazolam is a triazolobenzodiazepine compound and serves as the active metabolite of Rilmazafone.</p>Fórmula:C19H15Cl2N5OCor e Forma:SolidPeso molecular:400.26Antidepressant agent 4
<p>Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.</p>Fórmula:C19H38ClN5O2SCor e Forma:SolidPeso molecular:436.065-MeO-MET
CAS:<p>5-MeO-MET (5-Methoxy-N-methyl-N-ethyltryptamine) is a compound belonging to the 5-methoxytryptamine class. It acts as an agonist for 5-HT1A and 5-HT2A receptors. In mice, 5-MeO-MET inhibits locomotion and has sedative effects.</p>Fórmula:C14H20N2OCor e Forma:SolidPeso molecular:232.32ACG548B
CAS:<p>ACG548B inhibits AChE/BChE with IC50s of 1.78/0.496 μM; favors AChE over BChE/ChoK.</p>Fórmula:C38H34Br2Cl2N4Cor e Forma:SolidPeso molecular:777.43Pyrantel hydrochloride
CAS:<p>Pyrantel hydrochloride is the hydrochloride form of Pyrantel. Pyrantel is is an anthelmintic and a nicotinic acetylcholine receptor (nAChR) agonist.</p>Fórmula:C11H15ClN2SPureza:98.01%Cor e Forma:SoildPeso molecular:242.77Fasciculic acid C
CAS:<p>Fasciculic acid C is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.</p>Fórmula:C38H63NO11Pureza:98%Cor e Forma:SolidPeso molecular:709.91ANQ-9040
CAS:<p>ANQ-9040 is a nondepolarizing neuromuscular relaxant of the steroid class.</p>Fórmula:C36H58N2O5SCor e Forma:SolidPeso molecular:630.92Methyl ganoderate A acetonide
CAS:<p>Methyl ganoderate A from Ganoderma lucidum is a natural AChE inhibitor (IC50=18.35 μM) for Alzheimer's research.</p>Fórmula:C34H50O7Cor e Forma:SolidPeso molecular:570.76Camlipixant
CAS:<p>Camlipixant (BLU-5937) is an orally active purine P2X3 receptor antagonist that is potent, selective and competitive.</p>Fórmula:C23H24F2N4O4Pureza:99.37%Cor e Forma:SoildPeso molecular:458.46Aceclidine (hydrochloride)
CAS:<p>agonist of muscarinic receptors</p>Fórmula:C9H16ClNO2Pureza:98%Cor e Forma:SolidPeso molecular:205.68Sodium Channel Targeted Library
<p>A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;</p>Cor e Forma:Odour SolidCrenezumab
CAS:<p>Crenezumab (MABT 5102A) is a fully humanized anti-amyloid-beta antibody that binds to multiple forms of amyloid-beta (Aβ) for the study of Alzheimer's disease.</p>Pureza:97.5% (SDS-PAGE); 95.3% (SEC-HPLC) - 97.5% (SDS-PAGE); 95.3% (SEC-HPLC)Cor e Forma:Liquid(Iso)-Samixogrel
CAS:<p>(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.</p>Fórmula:C25H25ClN2O4SPureza:98.80%Cor e Forma:SolidPeso molecular:484.993-Hydroxy desalkylflurazepam
CAS:<p>3-Hydroxy desalkylflurazepam is a benzodiazepine compound with potential sedative and anxiolytic effects.</p>Fórmula:C15H10ClFN2O2Cor e Forma:SolidPeso molecular:304.7TIP 39, Tuberoinfundibular Neuropeptide
CAS:<p>TIP39 is a synthetic neuropeptide agonist for human and rat PTH2 receptors from the hypothalamus.</p>Fórmula:C202H325N61O54SPureza:98%Cor e Forma:SolidPeso molecular:4504.2Methoxy-X04
CAS:<p>Methoxy-X04, a derivative of Congo red and Chrysamine-G, is a brain-permeable fluorescent probe for amyloid-β (Aβ).</p>Fórmula:C23H20O3Pureza:98.96%Cor e Forma:SolidPeso molecular:344.4(Iso)-Atagabalin HCl
CAS:<p>(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.</p>Fórmula:C10H20ClNO2Pureza:99.26% - >99.99%Cor e Forma:SoildPeso molecular:221.72Sabirnetug
CAS:<p>Sabirnetug is a humanized IgG2κ monoclonal antibody that specifically targets the amyloid-β (A4) precursor protein.</p>Cor e Forma:LiquidAnagyrine hydrochloride
CAS:<p>Anagyrine hydrochloride, a quinolizidine from Lupinus albus, targets muscarinic/nicotinic receptors; IC50: 132/2096 µM. It desensitizes nAChR directly.</p>Fórmula:C15H21ClN2OCor e Forma:SolidPeso molecular:280.79Xylamidine
CAS:<p>Xylamidine is a biochemical.</p>Fórmula:C19H24N2O2Cor e Forma:SolidPeso molecular:312.41Antidepressant agent 5
CAS:<p>Antidepressant agent 5 is a 7-substituted tetrahydroisoquinoline derivative with antidepressant activity.Antidepressant agent 5 acts similarly to magnoflorine</p>Fórmula:C20H25NO3Pureza:99.34%Cor e Forma:SoildPeso molecular:327.42nAChR modulator-2
CAS:<p>nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator [1] .</p>Fórmula:C12H8ClN3O2Cor e Forma:SolidPeso molecular:261.66Proadrenomedullin (1-20), human
CAS:<p>Endogenous peptide; agonist of MRGPRX2 (EC50=251 nM); noncompetitive inhibitor of nicotinic receptors; reduces catecholamine secretion; antihypertensive.</p>Fórmula:C112H178N36O27Pureza:98%Cor e Forma:SolidPeso molecular:2460.84CGP 35348
CAS:<p>CGP 35348 是 GABAB 受体的选择性拮抗剂 (EC50 = 34 μM)。 CGP 35348 可用于研究白化新生小鼠脑损伤后的神经肌肉协调和空间学习。</p>Fórmula:C8H20NO4PPureza:≥98%Cor e Forma:SolidPeso molecular:225.22Encecalinol
CAS:<p>Encecalinol, a compound isolated from the aerial parts of Ageratina grandifolia, acts as a potent inhibitor of calmodulin [1].</p>Fórmula:C14H18O3Cor e Forma:SolidPeso molecular:234.29BChE-IN-16
<p>BChE-IN-16 (compound 87) is a potent inhibitor of human butyrylcholinesterase (hBChE) exhibiting an inhibition concentration half-maximum (IC50) of 3.8 nM.</p>Fórmula:C28H32FNO2Cor e Forma:SolidPeso molecular:433.56[D-Trp7,9,10]-Substance P
CAS:<p>Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.</p>Fórmula:C79H105N21O13SPureza:98%Cor e Forma:SolidPeso molecular:1588.895-methoxy-α-Ethyltryptamine
CAS:<p>5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects. </p>Fórmula:C13H18N2OPureza:98.25%Cor e Forma:SolidPeso molecular:218.29CALP2
CAS:<p>CALP2 is a CaM antagonist blocking EF-hand/Ca2+ site; inhibits CaM phosphodiesterase, raises Ca2+, and activates alveolar macrophages.</p>Fórmula:C68H104N14O13SPureza:98%Cor e Forma:SolidPeso molecular:1357.72LOX-IN-4
CAS:<p>LOX-IN-4 (Compound 112) is an inhibitor of lysyl oxidase (LOX). It holds potential for use in cancer research.</p>Fórmula:C20H24Cl2FN3O2SCor e Forma:SolidPeso molecular:460.39β-Amyloid (35-42)
CAS:<p>β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.</p>Fórmula:C33H60N8O9SPureza:98%Cor e Forma:SolidPeso molecular:744.94Lesogaberan napadisylate
CAS:<p>Lesogaberan (AZD-3355) is a selective GABAB agonist with EC50 of 8.6 nM, Ki of 5.1 nM in rats, and acts peripherally on the esophageal sphincter.</p>Fórmula:C13H17FNO5PSCor e Forma:SolidPeso molecular:349.31AChE/BChE-IN-14
<p>AChE/BChE-IN-14 (compound 13), a benzylisoquinoline alkaloid extracted from Fissistigma polyanthum roots, demonstrates inhibitory effects on both</p>Fórmula:C19H23NO3Cor e Forma:SolidPeso molecular:313.39pCPA methyl ester hydrochloride
CAS:<p>pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.</p>Fórmula:C10H13Cl2NO2Pureza:99.73% - 99.88%Cor e Forma:SolidPeso molecular:250.12Chrysophanol-1-O-β-gentiobioside
CAS:<p>Chrysophanol-1-O-β-gentiobioside, an anthraquinone glycoside obtained from the seeds of Cassia obtusifolia, exhibits targeted inhibition of hMAO-A isozyme</p>Fórmula:C27H30O14Cor e Forma:SolidPeso molecular:578.52Brexpiprazole S-oxide D8
CAS:<p>Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.</p>Fórmula:C25H19D8N3O3SPureza:98%Cor e Forma:SolidPeso molecular:457.61GSK-3β inhibitor 27
<p>GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.</p>Fórmula:C16H17ClN4O2Cor e Forma:SolidPeso molecular:332.79Biphenyl-3′,3,4,4′-tetrol
CAS:<p>Biphenyl-3′,3,4,4′-tetrol (BPT) is a potent inhibitor of Aβ40 aggregation and can be utilized in research related to neurodegenerative diseases such as Alzheimer's.</p>Fórmula:C12H10O4Cor e Forma:SolidPeso molecular:218.21β-Amyloid (1-9)
CAS:<p>This is an N-terminal fragment of beta amyloid.</p>Fórmula:C42H60N14O17Pureza:98%Cor e Forma:SolidPeso molecular:1033.01LY3027788 hydrochloride
CAS:<p>LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.</p>Fórmula:C25H32ClF2NO11SCor e Forma:SolidPeso molecular:628.03p-MPPF
CAS:<p>p-MPPF is a 5-HT antagonist that can be used to study neurological diseases.</p>Fórmula:C25H27FN4O2Pureza:99.92%Cor e Forma:SolidPeso molecular:434.51Aminoacetone hydrochloride
CAS:<p>Aminoacetone hydrochloride (1-Aminoacetone Hydrochloride) is an oxidative agent that induces loss of ferritin ferrireductase activity and iron uptake.</p>Fórmula:C3H8ClNOPureza:99.76%Cor e Forma:SolidPeso molecular:109.56AChE-IN-45
<p>AChE-IN-45 (Compound 14) is an acetylcholinesterase (AChE) inhibitor exhibiting an IC50 value of 11.57±0.45 nM, and it demonstrates both antioxidant and</p>Cor e Forma:Odour SolidDoxacurium Chloride
CAS:<p>Doxacurium Chloride is a muscarinic acetylcholine receptor M2 antagonist.</p>Fórmula:C56H78ClN2O16Pureza:98%Cor e Forma:SolidPeso molecular:1070.69Alverine hydrochloride
CAS:<p>Alverine hydrochloride is a parasympatholytic.</p>Fórmula:C20H28ClNCor e Forma:SolidPeso molecular:317.9Fluphenazine-N-2-chloroethane (hydrochloride)
CAS:<p>Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.</p>Fórmula:C22H27Cl3F3N3SCor e Forma:SolidPeso molecular:528.89Lupanine hydrochloride
CAS:<p>Lupanine hydrochloride, a Sparteine derivative, binds to nAChR with a Ki of 500 nM and has ganglioplegic properties.</p>Fórmula:C15H25ClN2OCor e Forma:SolidPeso molecular:284.834-P-PDOT
CAS:<p>4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.</p>Fórmula:C19H21NOPureza:99.91%Cor e Forma:SolidPeso molecular:279.38Oxotremorine
CAS:<p>Oxotremorine acts as an agonist of mAChR, specifically activating the M1 and M3 acetylcholine receptors. In drug discrimination experiments with macaques, it exhibits effects similar to nicotine.</p>Fórmula:C12H18N2OCor e Forma:SolidPeso molecular:206.28SSAO inhibitor-1
CAS:<p>SSAO Inhibitor-1 blocks SSAO, has anti-inflammatory effects, used in liver disease research.</p>Fórmula:C17H24FN5O2Cor e Forma:SolidPeso molecular:349.41Emamectin B1a
CAS:<p>Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.</p>Fórmula:C49H75NO13Cor e Forma:SolidPeso molecular:886.133BChE-IN-40
<p>BChE-IN-40 (compound D40) is a potent butyrylcholinesterase inhibitor with an IC50 of 0.59 μM. It demonstrates significant anti-inflammatory effects, with an IC50 of 4.55 μM in inhibiting nitric oxide production. Additionally, BChE-IN-40 exhibits excellent permeability across the blood-brain barrier.</p>Fórmula:C28H30N2O7Cor e Forma:SolidPeso molecular:506.2053DISC-0974
<p>DISC-0974 is a humanized antibody targeting RGMC/HFE2, which can be used to study urogenital system diseases.</p>Cor e Forma:LiquidPeso molecular:145.5kDaHeliosupine
<p>Heliosupine is a useful organic compound for research related to life sciences and the catalog number is T125038.</p>Fórmula:C20H31NO7Cor e Forma:SolidPeso molecular:397.468CHF-5022
CAS:<p>CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).</p>Fórmula:C17H12F4O2Cor e Forma:SolidPeso molecular:324.27Vortioxetine D8
CAS:<p>Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).</p>Fórmula:C18H22N2SPureza:98%Cor e Forma:SolidPeso molecular:306.5Epiboxidine
CAS:<p>Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.</p>Fórmula:C10H14N2OCor e Forma:SolidPeso molecular:178.23Mirtazapine N-oxide
CAS:<p>Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.</p>Fórmula:C17H19N3OCor e Forma:SolidPeso molecular:281.359SB656104
CAS:<p>SB656104 is a bioactive chemical.</p>Fórmula:C25H30ClN3O3SCor e Forma:SolidPeso molecular:488.04Kynuramine
CAS:<p>Kynuramine is an aromatic ketone containing the aniline structure.</p>Fórmula:C9H12N2OCor e Forma:SolidPeso molecular:164.20Methylatropine (nitrate)
CAS:<p>Methylatropine: Muscarinic antagonist, <0.1 nM IC50, atropine derivative, lowers ACh's effect on BP, affects salivation, pupil dilation, heart rate.</p>Fórmula:C18H26N2O6Cor e Forma:SolidPeso molecular:366.414Blestrin D
CAS:<p>Blestrin D: BChE mixed-type inhibitor, IC50=8.1μM, from Bletilla striata, for AD research.</p>Fórmula:C30H24O6Cor e Forma:SolidPeso molecular:480.51AChE-IN-43
<p>AChE-IN-43 is a potent, selective AChE inhibitor with a K i of 0.41 μM, applicable in the study of neurological diseases [1].</p>Cor e Forma:Odour SolidZL-1101
<p>ZL-1101 is a human monoclonal antibody (mAb) targeting TNFRSF4/OX40/CD134.</p>Cor e Forma:Odour Liquidepi-Aszonalenin A
CAS:<p>epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.</p>Fórmula:C25H25N3O3Cor e Forma:SolidPeso molecular:415.48Nardoguaianone J
CAS:<p>Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].</p>Fórmula:C15H22O2Cor e Forma:SolidPeso molecular:234.33JH-XII-03-02
CAS:<p>JH-XII-03-02 is a potent and selective leucine-rich repeat kinase 2 (LRRK2) proteolysis targeting chimera (PROTAC) degrader, utilized in Parkinson's Disease (PD</p>Fórmula:C43H51N9O10Pureza:98%Cor e Forma:SolidPeso molecular:853.92Calmodulin Binding Peptide 1
CAS:<p>Calmodulin Binding Peptide 1, a high-affinity MLCK-derived inhibitor, blocks IP3-induced Ca2+ release.</p>Fórmula:C231H373N69O70S2Pureza:98%Cor e Forma:SolidPeso molecular:5301.1
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