Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(939 produtos)
- ACK(1 produtos)
- AChR(574 produtos)
- ATP Citrato Liase(16 produtos)
- Receptor adrenérgico(2.943 produtos)
- BACE(36 produtos)
- Beta Amilóide(204 produtos)
- CaMK(68 produtos)
- COX(561 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor GABA(336 produtos)
- Gama-secretase(59 produtos)
- GluR(255 produtos)
- GlyT(24 produtos)
- Receptor de Histamina(358 produtos)
- LRRK2(33 produtos)
- Receptor de Melatonina(24 produtos)
- NMDAR(28 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(297 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5397 produtos de "Neurociência"
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AMPA receptor antagonist-3
CAS:<p>AMPA receptor antagonist-3 is an AMPA receptor antagonist.</p>Fórmula:C20H19N5O2SPureza:99.79%Cor e Forma:SolidPeso molecular:393.46CGP 78608 hydrochloride
CAS:<p>CGP 78608 hydrochloride: NMDA receptor antagonist (IC50=6 nM), anticonvulsant, enhances GluN1/GluN3A currents (EC50=26.3 nM).</p>Fórmula:C11H14BrClN3O5PPureza:99.85%Cor e Forma:SolidPeso molecular:414.58Rislenemdaz
CAS:<p>Rislenemdaz (CERC-301) (CERC-301) is an antagonist of the N-methyl-D-aspartate (NMDA) receptor subunit 2B (GluN2B).</p>Fórmula:C19H23FN4O2Pureza:98.18%Cor e Forma:SolidPeso molecular:358.41Didesmethyl cariprazine
CAS:<p>Didesmethyl cariprazine, Cariprazine's active metabolite, treats schizophrenia/bipolar with D3/D2 affinity; half-life 1-3 weeks.</p>Fórmula:C19H28Cl2N4OPureza:99.52%Cor e Forma:SolidPeso molecular:399.36Tematropium
CAS:<p>Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.</p>Fórmula:C21H31NO8SPureza:99.89%Cor e Forma:SolidPeso molecular:457.54SB 216641 hydrochloride
CAS:<p>SB 216641 hydrochloride (SB-216641A) is a 5-HT1B/D receptor antagonist with anxiolytic properties.</p>Fórmula:C28H31ClN4O4Pureza:98.06% - 99.23%Cor e Forma:SolidPeso molecular:523.02BuChE-IN-TM-10
CAS:<p>TM-10: Potent BuChE inhibitor, IC50 8.9 nM, disaggregates Aβ, antioxidant, BBB penetrant, may treat Alzheimer's.</p>Fórmula:C32H38N2O3Pureza:99.54%Cor e Forma:SolidPeso molecular:498.66γ-Secretase-IN-1
CAS:<p>γ-Secretase-IN-1 is a γ-secretase inhibitor that displays partial antiproliferative activity against T-47D cells.</p>Fórmula:C27H24F2N4O3Pureza:99.56%Cor e Forma:SolidPeso molecular:490.5Dalzanemdor
CAS:<p>Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington's chorea, Alzheimer's disease, and cognitive</p>Fórmula:C27H43F3O2Pureza:98.2% - >99.99%Cor e Forma:SolidPeso molecular:456.62Philanthotoxin 74 dihydrochloride
CAS:<p>Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1.</p>Fórmula:C24H44Cl2N4O3Pureza:99.75%Cor e Forma:SolidPeso molecular:507.54AMPA receptor modulator-1
CAS:<p>AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.</p>Fórmula:C16H11ClF3NO2Pureza:99.93%Cor e Forma:SolidPeso molecular:341.71JNJ-42253432
CAS:<p>JNJ-42253432 is an oral active P2X7 antagonist capable of penetrating the central nervous system with a pKi value of 9.1 for rat and 7.9 for human P2X7 channels</p>Fórmula:C28H38N4OPureza:99.98%Cor e Forma:SolidPeso molecular:446.63Osemozotan HCl
CAS:<p>Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder.</p>Fórmula:C19H22ClNO5Pureza:98.87% - 99.63%Cor e Forma:SolidPeso molecular:379.84Atabecestat
CAS:<p>Atabecestat (JNJ-54861911) is an oral BACE1 inhibitor for Alzheimer's treatment with strong brain uptake and lasting PK/PD effects.</p>Fórmula:C18H14FN5OSPureza:99.21% - 99.77%Cor e Forma:SolidPeso molecular:367.4WAY-607695
CAS:<p>WAY-607695 is a potential 5-HT1A receptor agonist.</p>Fórmula:C13H12FNO2Pureza:99.82%Cor e Forma:SolidPeso molecular:233.24VU6004909
CAS:<p>VU6004909 is an mGlu5 receptor orthosteric modulator that reverses MK801-induced increased cortical activity and cognitive dysfunction.</p>Fórmula:C21H15FN2O4Pureza:96.68% - 98.44%Cor e Forma:SolidPeso molecular:378.35TZ3O
CAS:<p>TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment in Scopolamine-induced Alzheimer's type model in rats.</p>Fórmula:C18H13NO4SPureza:99.84%Cor e Forma:SolidPeso molecular:339.37PXS-5153A
CAS:<p>PXS-5153A rapidly inhibits lysyl oxidase 2/3 enzymes, blocks activity in 15 mins, and reduces fibrosis.</p>Fórmula:C20H25Cl2FN4O2SPureza:99.58%Cor e Forma:SolidPeso molecular:475.41Lumateperone
CAS:<p>Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).</p>Fórmula:C24H28FN3OPureza:99.68% - 99.91%Cor e Forma:SolidPeso molecular:393.5BMS-986176
CAS:<p>AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).</p>Fórmula:C19H23F4N3OPureza:98.58% - 98.7%Cor e Forma:SolidPeso molecular:385.4MDR-1339
CAS:<p>MDR-1339 is a blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.</p>Fórmula:C20H22O4Pureza:98.57%Cor e Forma:SolidPeso molecular:326.39PXS-5120A
CAS:<p>PXS-5120A is an irreversible fluoroallylamine Lysyl Oxidase-like 2/3 (LOXL2/3) inhibitor with anti-fibrotic activity.</p>Fórmula:C22H25ClFN3O4SPureza:97.02%Cor e Forma:SolidPeso molecular:481.97SB-616234-A
CAS:<p>SB-616234-A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant activity.</p>Fórmula:C32H36ClN5O3Pureza:99.72%Cor e Forma:SolidPeso molecular:574.11TDI-11861
CAS:<p>TDI-11861 is a second-gen sAC (ADCY10) inhibitor with an IC50 of 5.5 nM and slow dissociation.</p>Fórmula:C22H25ClF2N6O3Cor e Forma:SolidPeso molecular:494.925-HT6R/MAO-B modulator 1
<p>5-HT6R/MAO-B modulator 1 blocks 5-HT6R and permanently inhibits MAO-B, protects glial cells, and reverses memory loss.</p>Fórmula:C33H38N4O3SCor e Forma:SolidPeso molecular:570.74Moxetomidate
CAS:<p>Moxetomidate is a GABAA receptor (GABAA receptor) agonist with hypnotic properties.</p>Fórmula:C15H18N2O3Cor e Forma:SolidPeso molecular:274.315YM 202074
CAS:<p>metabotropic glutamate receptor type 1 (mGlu1) antagonist</p>Fórmula:C56H72N8O16S2Pureza:98%Cor e Forma:SolidPeso molecular:1177.34MAO-B-IN-10
<p>MAO-B-IN-10: Potent, selective MAO-B inhibitor; crosses blood-brain barrier; IC50 5.3 μM; reduces Aβ aggregation 58.2%, disaggregates 43.3%.</p>Fórmula:C23H26N2O4Cor e Forma:SolidPeso molecular:394.46Glutaminyl Cyclase Inhibitor 3
CAS:<p>Designed anti-Alzheimer’s compound; potent Glutaminyl Cyclase inhibitor; IC50 at 4.5 nM; reduces brain Aβ; improves cognition.</p>Fórmula:C24H32N6O2SPureza:98%Cor e Forma:SolidPeso molecular:468.61AChE-IN-83
CAS:<p>AChE-IN-83 (compound f1) is an AChE inhibitor that suppresses nematode growth and acetylcholinesterase activity in rice seeds while being safe for the seeds. It specifically targets Aphelenchoides besseyi, with an LC50 of 19.0 μg/mL over 48 hours. AChE-IN-83 impedes nematode populations and behaviors in rice seeds, damages the nematode cuticle, and induces reactive oxygen species, lipofuscin, and lipid generation within the nematodes.</p>Fórmula:C10H7ClN2O2SCor e Forma:SolidPeso molecular:254.693(S)-Praziquantel
CAS:<p>(S)-Praziquantel is the inactive isomer of R-praziquantel.</p>Fórmula:C19H24N2O2Cor e Forma:SolidPeso molecular:312.406LP 12 hydrochloride hydrate
<p>LP 12 hydrochloride hydrate: potent, selective 5-HT7 agonist (Ki: 0.13 nM); less affinity for D2, 5-HT1A/2A receptors.</p>Fórmula:C32H39N3O·HCl·xH2OCor e Forma:SolidAAZ-A 154 mesylate
CAS:<p>AAZ-A 154 mesylate mesylate is a selective, competitive, and non-hallucinogenic antagonist of 5-HT2AR. It enhances neuronal growth in rodents and produces enduring beneficial behavioral effects.</p>Fórmula:C15H24N2O4SCor e Forma:SolidPeso molecular:328.43FP0429
CAS:<p>FP0429 is an agonist of mGlu4.</p>Fórmula:C10H12N2O7Pureza:98%Cor e Forma:SolidPeso molecular:272.21VU6016235
CAS:<p>VU6016235 is a structurally unique, orally available, and highly selective tricyclic M4 muscarinic acetylcholine receptor positive allosteric modulator.</p>Fórmula:C21H22N4OSCor e Forma:SolidPeso molecular:378.49SB 243213 hydrochloride
CAS:<p>SB 243213 hydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8).It</p>Fórmula:C22H20ClF3N4O2Pureza:98%Cor e Forma:SolidPeso molecular:464.875-HT1A antagonist 1
<p>Compound 6f is a potent, selective 5-HT1A receptor blocker (Ki: 35 nM), useful in CNS disorder research.</p>Fórmula:C23H29ClN6O2Cor e Forma:SolidPeso molecular:456.971,9-Dideoxyforskolin
CAS:<p>The compound is an inactive analog of forskolin(an adenylyl cyclase activator).</p>Fórmula:C22H34O5Pureza:98%Cor e Forma:SolidPeso molecular:378.5BPN-15606 besylate
<p>BPN-15606 besylate is a potent oral γ-secretase regulator reducing Aβ42 and Aβ40 with good pharmacokinetics. IC50: 7 nM (Aβ42), 17 nM (Aβ40).</p>Fórmula:C29H29FN6O4SCor e Forma:SolidPeso molecular:576.64LRRK2-IN-6
<p>LRRK2-IN-6 is an oral, selective LRRK2 inhibitor crossing the blood-brain barrier, targeting GS (IC50: 4.6μM) and WT LRRK2 (IC50: 49μM).</p>Fórmula:C23H24F2N4O2SCor e Forma:SolidPeso molecular:458.52Rodatristat ethyl
CAS:<p>Rodatristat ethyl is an oral TPH1 inhibitor reducing 5-HT levels & lowering PAH at low doses.</p>Fórmula:C29H31ClF3N5O3Pureza:98%Cor e Forma:SolidPeso molecular:590.04Elzasonan hydrochloride
CAS:<p>Elzasonan hydrochloride is a serotonin 1B and serotonin 1D receptor antagonist. It is utilized in the study of depression.</p>Fórmula:C22H24Cl3N3OSCor e Forma:SolidPeso molecular:484.87hMAO-B-IN-10
<p>hMAO-B-IN-10 (compound 7) is an inhibitor of MAO-A/B with IC50 values of 424.1 nM and 177.9 nM, respectively. It has demonstrated neuroprotective effects in the MPTP-induced mouse model of Parkinson's Disease (PD).</p>Fórmula:C16H12N4O4Cor e Forma:SolidPeso molecular:324.29TP003
CAS:<p>TP003 is a novel non-selective GABAA receptor benzodiazepine site agonist with affinity for α1β2gam2, α2β3gam2, α3β3gam2, α5β2gam2, EC50 of 20.3, 10.6, 3.24, 5.</p>Fórmula:C23H16F3N3OPureza:99.17%Cor e Forma:SolidPeso molecular:407.39nAChR antagonist 1
CAS:<p>Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.</p>Fórmula:C19H22N4O2Cor e Forma:SolidPeso molecular:338.4YNT-3708
CAS:<p>YNT-3708 is an orexin receptor (OXR) agonist, exhibiting EC50 values of 14.6 nM for OX1R and 277 nM for OX2R.</p>Fórmula:C35H36N4O6SCor e Forma:SolidPeso molecular:640.749γ-Secretase modulator 11 hydrochloride
CAS:<p>γ-Secretase modulator 11 hydrochloride is a potent, orally active γ-secretase modulator (IC50: 0.029 μM).</p>Fórmula:C28H23ClF2N4O2Cor e Forma:SolidPeso molecular:520.96γ-secretase modulator 5
<p>Compound 22d is a GSM that crosses the blood-brain barrier, inhibits Aβ42 production (IC50: 60 nM), and may help study Alzheimer's.</p>Cor e Forma:SolidMesulergine hydrochloride
CAS:<p>5-HT2A and 2C receptor antagonist</p>Fórmula:C18H27ClN4O2SPureza:98%Cor e Forma:SolidPeso molecular:398.95LRRK2-IN-3
CAS:<p>LRRK2-IN-3: potent, selective oral LRRK2 blocker, BBB-penetrant, IC50 of 0.6 nM in hPBMCs, for Parkinson's research.</p>Fórmula:C25H29ClF2N6O2Cor e Forma:SolidPeso molecular:518.99
