Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(940 produtos)
- ACK(1 produtos)
- AChR(574 produtos)
- ATP Citrato Liase(16 produtos)
- Receptor adrenérgico(2.942 produtos)
- BACE(36 produtos)
- Beta Amilóide(204 produtos)
- CaMK(68 produtos)
- COX(562 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor GABA(336 produtos)
- Gama-secretase(59 produtos)
- GluR(255 produtos)
- GlyT(24 produtos)
- Receptor de Histamina(358 produtos)
- LRRK2(33 produtos)
- Receptor de Melatonina(24 produtos)
- NMDAR(28 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(296 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5400 produtos de "Neurociência"
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(Met(O)35)-Amyloid β-Protein (1-42)
<p>(Met(O)35)-Amyloid β-Protein (1-42) represents the oxidized form of Methionine 35 in Aβ42, capable of producing an oligomer size distribution akin to that of</p>Fórmula:C203H311N55O61SCor e Forma:SolidPeso molecular:4530.04CALP2 TFA
<p>CALP2 TFA, a CaM antagonist with 7.9 µM Kd, blocks CaM-dependent enzymes, boosts Ca2+ levels, and activates macrophages.</p>Fórmula:C70H105F3N14O15SCor e Forma:SolidPeso molecular:1471.72Amyloid β-Protein (3-42)
CAS:<p>Amyloid β-Protein (3-42), the precursor of Pyr peptide, serves as the foundation of the amyloid template block in Alzheimer's disease when modified to</p>Cor e Forma:SolidSKF-83566 hydrochloride
CAS:<p>SKF-83566 hydrochloride is a D1-like dopamine receptor antagonist, inhibiting dopamine transporters and mitigating GBP-induced CPP.</p>Fórmula:C17H19BrClNOPureza:99.27%Cor e Forma:SoildPeso molecular:368.69(Rac)-5-Carboxy tolterodine
CAS:<p>(Rac)-5-Carboxy tolterodine is an inactive metabolite of Tolterodine, which acts as a muscarinic acetylcholine receptor antagonist.</p>Fórmula:C22H29NO3Cor e Forma:SolidPeso molecular:355.47AC3-I, myristoylated
<p>Myristoylated AC3-I is a biologically active peptide and a myristoylated variant of the Autocamtide-3-Derived Inhibitory Peptide (AC3-I).</p>Fórmula:C78H137N21O20Pureza:98%Cor e Forma:SolidPeso molecular:1689.05Lisuride maleate
CAS:<p>Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.</p>Fórmula:C24H30N4O5Pureza:99.85%Cor e Forma:SolidPeso molecular:454.52LE 300
CAS:<p>LE 300 represents a structurally novel type of antagonists acting preferentially at the dopamine D(1)/D(5)receptors and the serotonin 5-HT(2A)receptor.</p>Fórmula:C20H22N2Pureza:97.91% - 98.79%Cor e Forma:SolidPeso molecular:290.4nAChR agonist 2
CAS:<p>Compound 8, identified as a selective alpha4beta2 (α4β2) neuronal acetylcholine receptor (nAChR) agonist, demonstrates a dissociation constant (Kd) of 26 nM,</p>Fórmula:C11H16N2Cor e Forma:SolidPeso molecular:176.263Guvacine hydrobromide
CAS:<p>Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake.</p>Fórmula:C6H10BrNO2Pureza:98%Cor e Forma:SolidPeso molecular:208.05R 50595
CAS:<p>R 50595 is a selective non-competitive cisapride antagonist.</p>Fórmula:C30H35Cl2F2N3O3Pureza:98%Cor e Forma:SolidPeso molecular:594.52AChE-IN-46
<p>AChE-IN-46 (compound 4), a β-cyclocostunolide, functions as an acetylcholinesterase (AChE) inhibitor [1].</p>Fórmula:C15H22O2Cor e Forma:SolidPeso molecular:234.33pCPA methyl ester hydrochloride
CAS:<p>pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.</p>Fórmula:C10H13Cl2NO2Pureza:99.73% - 99.88%Cor e Forma:SolidPeso molecular:250.12Argiotoxin 636
CAS:<p>Argiotoxin 636 is a toxin and serves as a non-specific, non-competitive, and effective antagonist of ionotropic glutamate receptors (iGluR). It inhibits excitatory synaptic transmission in neurons and has paralyzing and muscle relaxant effects. Argiotoxin 636 can be utilized for research in neurological disorders.</p>Fórmula:C29H52N10O6Cor e Forma:SolidPeso molecular:636.794-Iodoamphetamine hydrochloride
CAS:<p>4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated phenethylamine characterized by the presence of an iodine atom at the para position of the phenyl group. It selectively induces serotonin release and inhibits reuptake in rat brain synaptosomes.</p>Fórmula:C9H13ClINCor e Forma:SolidPeso molecular:297.56LY 344864 racemate
CAS:<p>LY 344864 racemate is a 5-HT1F receptor agonist.</p>Fórmula:C21H22FN3OPureza:99.75%Cor e Forma:SoildPeso molecular:351.42MAO-B-IN-4
<p>MAO-B-IN-4 (Compound 26) is a reversible monoamine oxidase B (MAO-B) inhibitor with potent in vitro activity, characterized by an IC50 value of 9 nM.</p>Fórmula:C23H20ClF2N3Pureza:98%Cor e Forma:SolidPeso molecular:411.87Amyloid-Forming peptide GNNQQNY
CAS:<p>Amyloid-Forming peptide GNNQQNY, a biologically active heptapeptide derived from the N-terminal prion-determining domain of yeast Sup35, is instrumental in</p>Fórmula:C33H48N12O14Cor e Forma:SolidPeso molecular:836.81Aβ-IN-7
<p>Aβ-IN-7 (compound 5a) acts as a potent inhibitor of Aβ aggregation, stabilizing Aβ monomers at 50 μM concentration to prevent them from forming larger oligomers</p>Fórmula:C14H10N2SCor e Forma:SolidPeso molecular:238.31(-)-Eseroline fumarate
CAS:<p>(-)-Eseroline fumarate, a Physostigmine metabolite and AChE inhibitor, triggers cancer cell LDH release and neuronal cell death.</p>Fórmula:C17H22N2O5Cor e Forma:SolidPeso molecular:334.37Salvianolic acid H
CAS:<p>Salvianolic acid H is a strong inhibitor of acetylcholinesterase (AChE) [1].</p>Fórmula:C27H22O12Cor e Forma:SolidPeso molecular:538.46Dalidnetug
CAS:<p>Dalidnetug is a humanized monoclonal antibody that targets human β-amyloid precursor protein (APP). By specifically binding to APP, Dalidnetug reduces the production of β-amyloid (Aβ), thereby demonstrating activity in clearing β-amyloid. This compound holds potential for research in Alzheimer's disease.</p>Cor e Forma:LiquidC175-0062
CAS:<p>C175-0062, a monoamine oxidase B (MAO-B) inhibitor, is applicable in research focused on neurodegenerative disorders such as Parkinson's disease (PD), Alzheimer's disease (AD), and amyotrophic lateral sclerosis (ALS) [1].</p>Fórmula:C21H18N2O5Cor e Forma:SolidPeso molecular:378.38Adatanserin hydrochloride
CAS:<p>Adatanserin hydrochloride (WY50324 hydrochloride) is a 5-HT(1A)/5-HT(2) receptor ligand that is neuroprotective and may be used in the study of depression.</p>Fórmula:C21H32ClN5OPureza:99.64%Cor e Forma:SolidPeso molecular:405.96nAChR modulator-1
CAS:<p>nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .</p>Fórmula:C12H8ClN3O2Cor e Forma:SolidPeso molecular:261.66YS-370
CAS:<p>YS-370 orally blocks P-gp, moderately inhibits CYP3A4, reverses drug resistance, and enhances paclitaxel's anticancer effects.</p>Fórmula:C37H35BrN4O3Pureza:98.055%Cor e Forma:SolidPeso molecular:663.6LEK 8804
CAS:<p>LEK 8804 is a 5-HT(2) receptor antagonist and 5-HT(1A) receptor agonist.</p>Fórmula:C19H19N3OCor e Forma:SolidPeso molecular:305.37β-Secretase inhibitor-STA
CAS:<p>BACE-IN-1 is amyloid precursor protein beta-secretase inhibitor</p>Fórmula:C73H118N16O27Pureza:98%Cor e Forma:SolidPeso molecular:1651.81LY3020371
CAS:<p>LY3020371: potent, selective mGlu 2/3 receptor antagonist with Ki of 5.26 nM (hmGluR2) and 2.50 nM (hmGluR3); key in depression studies.</p>Fórmula:C15H15F2NO5SCor e Forma:SolidPeso molecular:359.34K1833
<p>K1833 is an inhibitor and reactivator of human acetylcholinesterase (hrAChE), exhibiting an inhibition concentration (IC50) of 58$.</p>Cor e Forma:Odour Solid5-(2-Aminopropyl)indole
CAS:<p>5-(2-Aminopropyl)indole is an orally active psychoactive substance that inhibits monoamine oxidase (MAO) and exhibits long-lasting stimulant effects.</p>Fórmula:C11H14N2Cor e Forma:SolidPeso molecular:174.24Lysyl hydroxylase 2-IN-1
<p>"Lysyl Hydroxylase 2-IN-1 (compound 12) is a selective inhibitor of lysyl hydroxylase 2 (LH2) with an IC50 of approximately 300 nM and demonstrates specificity</p>Fórmula:C18H18N2O3Pureza:98%Cor e Forma:SolidPeso molecular:310.35Perlapine
CAS:<p>Perlapine is an effective and selective HM3DQ DREADD agonist (EC50 = 2.8 nM).</p>Fórmula:C19H21N3Cor e Forma:SolidPeso molecular:291.39Pomaglumetad methionil anhydrous
CAS:<p>LY2140023, potential schizophrenia treatment, is an oral prodrug of LY404039, a selective mGlu2/3 agonist.</p>Fórmula:C12H18N2O7S2Pureza:98%Cor e Forma:SolidPeso molecular:366.41EB-42486
CAS:<p>EB-42486 is an effective and highly selective inhibitor of G2019S-LRRK2 with an IC50 < 0.2 nM.</p>Fórmula:C22H22N8OPureza:99.53%Cor e Forma:SolidPeso molecular:414.46(-)-Coclaurine hydrochloride
CAS:<p>(-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum.</p>Fórmula:C17H20ClNO3Pureza:99.07%Cor e Forma:SoildPeso molecular:321.8Desmethyl Mirtazapine (hydrochloride)
CAS:<p>Desmethyl mirtazapine is a metabolite of the antidepressant mirtazapine.1It is formed from mirtazapine by the cytochrome P450 (CYP) isoform CYP3A4.</p>Fórmula:C16H18ClN3Cor e Forma:SolidPeso molecular:287.79ZZL-7
CAS:<p>ZZL-7 is a rapid antidepressant targeting nNOS & SERT in DRN, crosses blood-brain barrier, with MDD research potential.</p>Fórmula:C11H20N2O4Pureza:99.79%Cor e Forma:SoildPeso molecular:244.29NMDA receptor antagonist 7
<p>Compound (S)-10a, a GluN2B subunit-selective NMDA receptor antagonist, exhibits a K i of 93 nM and an IC 50 of 72 nM.</p>Fórmula:C22H27N3OPureza:98%Cor e Forma:SolidPeso molecular:349.47β-Secretase Inhibitor II
CAS:<p>β-Secretase Inhibitor II is a tripeptide aldehyde compound that acts as an inhibitor of β-Secretase.</p>Fórmula:C25H39N3O5Cor e Forma:SolidPeso molecular:461.59GluN2B receptor modulator-1
CAS:<p>GluN2B receptor modulator-1 is a selective negative allosteric modulator of NMDA receptor GluN2B subunits (IC50 31 nM), valuable for neuropharmacology studies.</p>Fórmula:C17H15F3N4O2SPureza:99.56%Cor e Forma:SolidPeso molecular:396.39Fentonium bromide
CAS:<p>Fentonium bromide is a biochemical.</p>Fórmula:C31H34BrNO4Cor e Forma:SolidPeso molecular:564.51Alosetron-d3
CAS:<p>Alosetron D3 (GR 68755 D3) is a deuterium-labeled Alosetron. Alosetron is an antagonist of 5HT3-receptor.</p>Fórmula:C17H18N4OPureza:98%Cor e Forma:SolidPeso molecular:297.37Lu AE51090
CAS:<p>Lu AE51090 is a selective muscarinic M1 receptor agonist with minimal off-target effects, receptor function and selective pharmacological modulation.</p>Fórmula:C24H29N3O3Pureza:99.57%Cor e Forma:SolidPeso molecular:407.51COX-1/2-IN-5
<p>COX-1/2-IN-5 (compound 2a) functions as a dual inhibitor of COX1/2, demonstrating inhibitory concentrations (IC50) of 2.650 μM and 0.958 μM, respectively, and</p>Fórmula:C21H22N2O5SPureza:98%Cor e Forma:SolidPeso molecular:414.47Hydroxytacrine maleate
CAS:<p>Hydroxytacrine maleate (Velnacrine maleate) is a cholinesterase inhibitor used in the study of Alzheimer's type dementia (SDAT).</p>Fórmula:C17H18N2O5Pureza:98.84%Cor e Forma:SolidPeso molecular:330.34N-Methylcyclohexaneethaneamine
CAS:<p>N-Methylcyclohexaneethaneamine is a useful organic compound for research related to life sciences.</p>Fórmula:C9H19NCor e Forma:SolidPeso molecular:141.2539BIBD-124
CAS:<p>BIBD-124, with an IC50 value of 9.51 nM, effectively binds to amyloid beta (Aβ) plaques.</p>Fórmula:C19H24FN3O3Cor e Forma:SolidPeso molecular:361.41(S)-3,4-DCPG HCl
<p>(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.</p>Fórmula:C10H10ClNO6Pureza:99.53% - 99.9%Cor e Forma:SoildPeso molecular:275.64Imagabalin
CAS:<p>Imagabalin is an active compound used in the study of neurological diseases.</p>Fórmula:C9H19NO2Cor e Forma:SolidPeso molecular:173.25
