Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(940 produtos)
- ACK(1 produtos)
- AChR(574 produtos)
- ATP Citrato Liase(16 produtos)
- Receptor adrenérgico(2.942 produtos)
- BACE(36 produtos)
- Beta Amilóide(204 produtos)
- CaMK(68 produtos)
- COX(562 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor GABA(336 produtos)
- Gama-secretase(59 produtos)
- GluR(255 produtos)
- GlyT(24 produtos)
- Receptor de Histamina(358 produtos)
- LRRK2(33 produtos)
- Receptor de Melatonina(24 produtos)
- NMDAR(28 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(296 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5400 produtos de "Neurociência"
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MK-0969
CAS:<p>MK-0969 (J-104135) is a possible M3 antagonist for the treatment of chronic obstructive pulmonary disease.</p>Fórmula:C24H30F2N4O2Cor e Forma:SolidPeso molecular:444.52Bis-(-)-8-demethylmaritidine
<p>Bis-(-)-8-demethylmaritidine, a natural alkaloid, serves as a potent inhibitor of acetylcholinesterase (AChE) and is utilized in Alzheimer's disease research [1</p>Cor e Forma:Odour SolidWithasomniferolide B
CAS:<p>Withasomniferolide B, a withanolide from Withania somnifera root, activates GABAA receptors.</p>Fórmula:C28H36O4Cor e Forma:SolidPeso molecular:436.58Antidepressant agent 3
<p>Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.</p>Fórmula:C17H30ClN5O2SCor e Forma:SolidPeso molecular:403.974-Butyl-α-agarofuran
CAS:<p>4-Butyl-alpha-agarofuran, a Gharu-wood derivative, is an anxiolytic, antidepressant, and aids neurological research.</p>Fórmula:C18H30OCor e Forma:SolidPeso molecular:262.43R-(+)-Cotinine
CAS:<p>R-(+)-Cotinine, an inactive nicotine metabolite, boosts Ach-induced current in human α7 nAChRs.</p>Fórmula:C10H12N2OCor e Forma:SolidPeso molecular:176.22β-Amyloid (12-20)
CAS:<p>β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad has</p>Fórmula:C57H83N15O11Pureza:98%Cor e Forma:SolidPeso molecular:1154.36BMS-906024
CAS:<p>BMS-906024 (Osugacestat) is a gamma secretase inhibitor, a Notch inhibitor.BMS-906024 has broad-spectrum antitumour activity.</p>Fórmula:C26H26F6N4O3Pureza:99.88% - >99.99%Cor e Forma:SolidPeso molecular:556.5mHTT-IN-1
CAS:<p>mHTT-IN-1 is a potent inhibitor of toxic mHTT, linked to Huntington's disease, with an EC50 of 46 nM.</p>Fórmula:C18H19N7OSCor e Forma:SolidPeso molecular:381.455-HT6R antagonist 1
<p>Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stability</p>Fórmula:C17H22F2N6OPureza:98%Cor e Forma:SolidPeso molecular:364.39LY836
<p>LY836 is an orally active, neuroprotective compound that effectively inhibits the PSD95-nNOS association in cortical neurons.</p>Pureza:98%Cor e Forma:Odour SolidMmTx1 toxin
<p>Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor's sensitivity to its agonist [1].</p>Fórmula:C295H455N95O97S10Pureza:98%Cor e Forma:SolidPeso molecular:7205CaMKIIα-PHOTAC
<p>CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα).</p>Fórmula:C54H58Cl2N10O11Pureza:98%Cor e Forma:SolidPeso molecular:1094MAO-B-IN-4
<p>MAO-B-IN-4 (Compound 26) is a reversible monoamine oxidase B (MAO-B) inhibitor with potent in vitro activity, characterized by an IC50 value of 9 nM.</p>Fórmula:C23H20ClF2N3Pureza:98%Cor e Forma:SolidPeso molecular:411.87Ro60-0175
CAS:<p>Ro60-0175 is a selective 5-HT2B and 5-HT2C serotonin receptor agonist, often used as fumarate.</p>Fórmula:C11H12ClFN2Pureza:97.09%Cor e Forma:SolidPeso molecular:226.68Lysyl hydroxylase 2-IN-1
<p>"Lysyl Hydroxylase 2-IN-1 (compound 12) is a selective inhibitor of lysyl hydroxylase 2 (LH2) with an IC50 of approximately 300 nM and demonstrates specificity</p>Fórmula:C18H18N2O3Pureza:98%Cor e Forma:SolidPeso molecular:310.35PD25
<p>PD25, an inhibitor of both AChE and BuChE, demonstrates inhibitory constants of hAChE IC50: 1.58 μM, eeAChE IC50: 1.63 μM, and eqBuChE IC50: 2.39 μM.</p>Fórmula:C25H24N2O4Cor e Forma:SolidPeso molecular:416.47NMDA receptor antagonist 7
<p>Compound (S)-10a, a GluN2B subunit-selective NMDA receptor antagonist, exhibits a K i of 93 nM and an IC 50 of 72 nM.</p>Fórmula:C22H27N3OPureza:98%Cor e Forma:SolidPeso molecular:349.47hAChE-IN-4
<p>Compd 5d (hAChE-IN-4) is a potent hAChE inhibitor that readily crosses the blood-brain barrier, exhibiting an IC50 of 0.25 μM, and is utilized in the study of</p>Fórmula:C30H23Cl3N2O3Cor e Forma:SolidPeso molecular:565.87IHC3
<p>IHC3 is a competitive and reversible monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.672 μM, which targets Cys172 within the enzyme's active site.</p>Fórmula:C17H12FN3OPureza:98%Cor e Forma:SolidPeso molecular:293.3MAOA-IN-1
<p>MAOA-IN-1 (compound 15) is an orally-active inhibitor of monoamine oxidase A (MAOA) that exhibits cytotoxic effects on prostate cancer cells.</p>Fórmula:C13H16Cl2N2O2Pureza:98%Cor e Forma:SolidPeso molecular:303.18GABA receptor Antagonist 1
<p>GABA receptor Antagonist 1 (compound 7w) effectively inhibits the Px RDL1 GABAR at an IC50 of 7.08 nmol/L and demonstrates insecticidal efficacy against P.</p>Pureza:98%Cor e Forma:Odour SolidMAO-B-IN-3
<p>MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a Ki</p>Fórmula:C24H25N3O2Pureza:98%Cor e Forma:SolidPeso molecular:387.47MAO-B-IN-18
<p>MAO-B-IN-18 is a potent, selective inhibitor of MAO B, demonstrating IC50 values of 52 nM for hMAO B and 14 μM for hMAO A.</p>Fórmula:C25H22N4O5Pureza:98%Cor e Forma:SolidPeso molecular:458.47Muscarine
CAS:<p>Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.</p>Fórmula:C9H20NO2Pureza:98%Cor e Forma:SolidPeso molecular:174.265-HT6 agonist 1
<p>Compound 19, a 5-HT6 agonist with an affinity (K i : 5 nM), exhibits antidepressant-like effects and enhances cognitive function while also inhibiting platelet</p>Fórmula:C17H22Cl2N6SPureza:98%Cor e Forma:SolidPeso molecular:413.37Syntide 2 TFA
<p>Syntide 2 (TFA) is a CaMKII substrate that selectively hinders GA response without affecting other plant processes.</p>Fórmula:C70H123N20F3O20Cor e Forma:SolidPeso molecular:1621.84MRS7925
<p>MRS7925 (Compound 43) serves as a potent antagonist of the 5-HT2B receptor, with an inhibition constant (Ki) of 17 nM, and is utilized in the study of fibrosis</p>Fórmula:C20H26IN5O3Pureza:98%Cor e Forma:SolidPeso molecular:511.36MAO-B-IN-25
<p>MAO-B-IN-25 (compound 92) is a selective inhibitor of monoamine oxidase B (MAO-B), exhibiting inhibitory half-maximal inhibitory concentrations (IC50) of 240 nM</p>Fórmula:C16H13BrO3Pureza:98%Cor e Forma:SolidPeso molecular:333.18Acetyl-Tau Peptide (273-284) amide
CAS:<p>Acetyl-Tau Peptide (273-284) amide inhibits Ac-Aβ(25–35)-NH2 aggregation and models Aβ/Tau interaction.</p>Fórmula:C64H116N18O17Cor e Forma:SolidPeso molecular:1409.72Arotinolol hydrochloride
CAS:<p>Arotinolol HCl is a non-selective α/β-blocker, anti-hypertensive, anti-obesity, and improves aortic stiffness.</p>Fórmula:C15H22ClN3O2S3Pureza:99.84%Cor e Forma:SolidPeso molecular:408BuChE-IN-13
<p>BuChE-IN-13 (compound 3) is a BuChE inhibitor that exhibits anti-Alzheimers activity. It is utilized in the research of neurodegenerative diseases.</p>Cor e Forma:Odour SolidmcK6A1
<p>mcK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.</p>Fórmula:C71H99N17O16Cor e Forma:SolidPeso molecular:1446.65(Met(O2)35)-Amyloid β-Protein (1-42)
<p>(Met(O2)35)-Amyloid β-Protein (1-42) is a peptide [1] .</p>Fórmula:C203H311N55O62SCor e Forma:SolidPeso molecular:4546.04(D-Asp1)-Amyloid β-Protein (1-42)
CAS:<p>(D-Asp1)-Amyloid β-Protein (1-42), a peptide fragment of amyloid β-protein (Aβ), serves as the primary constituent of vascular and parenchymal amyloid deposits</p>Fórmula:C203H311N55O60SCor e Forma:SolidPeso molecular:4514.04Lisuride maleate
CAS:<p>Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.</p>Fórmula:C24H30N4O5Pureza:99.85%Cor e Forma:SolidPeso molecular:454.52AChE/BuChE-IN-4
CAS:<p>AChE/BuChE-IN-4 is a multi-target AChE/BuChE inhibitor with IC50 values of 2.08 and 7.41 μM for AChE and BuChE, respectively.</p>Fórmula:C17H23N5Pureza:99.89%Cor e Forma:SoildPeso molecular:297.42,6-DMA hydrochloride
CAS:<p>2,6-DMA hydrochloride is a phenethylamine and acts as an agonist of the serotonin 5-HT2 receptor, with a pA2 value of 5.09.</p>Fórmula:C11H18ClNO2Cor e Forma:SolidPeso molecular:231.72Pyrazolam
CAS:<p>Pyrazolam is a psychoactive benzodiazepine compound serving as a central nervous system depressant. [Pyrazolam] can lead to psychomotor impairment.</p>Fórmula:C16H12BrN5Cor e Forma:SolidPeso molecular:354.2Dalidnetug
CAS:<p>Dalidnetug is a humanized monoclonal antibody that targets human β-amyloid precursor protein (APP). By specifically binding to APP, Dalidnetug reduces the production of β-amyloid (Aβ), thereby demonstrating activity in clearing β-amyloid. This compound holds potential for research in Alzheimer's disease.</p>Cor e Forma:LiquidN-Ethyl-N-(3-pyridylmethyl)amine
CAS:<p>N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.</p>Fórmula:C8H12N2Pureza:99.65%Cor e Forma:SolidPeso molecular:136.19Argiotoxin 636
CAS:<p>Argiotoxin 636 is a toxin and serves as a non-specific, non-competitive, and effective antagonist of ionotropic glutamate receptors (iGluR). It inhibits excitatory synaptic transmission in neurons and has paralyzing and muscle relaxant effects. Argiotoxin 636 can be utilized for research in neurological disorders.</p>Fórmula:C29H52N10O6Cor e Forma:SolidPeso molecular:636.79Rasagiline 13C3 mesylate racemic
CAS:<p>Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor.</p>Fórmula:C13H17NO3SPureza:98%Cor e Forma:SolidPeso molecular:270.32GluN2B receptor modulator-1
CAS:<p>GluN2B receptor modulator-1 is a selective negative allosteric modulator of NMDA receptor GluN2B subunits (IC50 31 nM), valuable for neuropharmacology studies.</p>Fórmula:C17H15F3N4O2SPureza:99.56%Cor e Forma:SolidPeso molecular:396.39Lu AE51090
CAS:<p>Lu AE51090 is a selective muscarinic M1 receptor agonist with minimal off-target effects, receptor function and selective pharmacological modulation.</p>Fórmula:C24H29N3O3Pureza:99.57%Cor e Forma:SolidPeso molecular:407.5125E-NBOMe hydrochloride
CAS:<p>25E-NBOMe hydrochloride is a derivative of 2C-E, featuring an N-(2-methoxybenzyl) addition to the amine group, and acts as a selective agonist of the 5-HT2A receptor.</p>Fórmula:C20H28ClNO3Cor e Forma:SolidPeso molecular:365.896-Fluoro-N,N-diethyltryptamine
CAS:<p>6-Fluoro-N,N-diethyltryptamine (6-F-DET) exhibits affinity for the 5-HT2A receptor.</p>Fórmula:C14H19FN2Cor e Forma:SolidPeso molecular:234.31MAO-B-IN-37
CAS:<p>MAO-B-IN-37 (Compound 37) is a derivative of TT01001 and acts as a selective inhibitor of monoamine oxidase B (MAO-B), with an IC50 of 270 nM. It exhibits good metabolic stability in mouse microsomes and shows strong affinity for human serum albumin.</p>Fórmula:C14H12FN3O3Cor e Forma:SolidPeso molecular:289.26Methamnetamine hydrochloride
CAS:<p>Methamnetamine (PAL-1046) hydrochloride is a psychoactive substance derived from phenethylamine, known to cause excessive serotonin release.</p>Fórmula:C14H18ClNCor e Forma:SolidPeso molecular:235.754-hydroxy DiPT hydrochloride
CAS:<p>4-hydroxy DiPT (hydrochloride) is a 5-HT2A agonist that can induce head twitch response (HTR) in mice, indicating its hallucinogenic potential. This compound holds promise for research into hallucinogens.</p>Fórmula:C16H25ClN2OCor e Forma:SolidPeso molecular:296.84
