Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(940 produtos)
- ACK(1 produtos)
- AChR(574 produtos)
- ATP Citrato Liase(16 produtos)
- Receptor adrenérgico(2.942 produtos)
- BACE(36 produtos)
- Beta Amilóide(204 produtos)
- CaMK(68 produtos)
- COX(562 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor GABA(336 produtos)
- Gama-secretase(59 produtos)
- GluR(255 produtos)
- GlyT(24 produtos)
- Receptor de Histamina(358 produtos)
- LRRK2(33 produtos)
- Receptor de Melatonina(24 produtos)
- NMDAR(28 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(296 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5400 produtos de "Neurociência"
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AC3-I, myristoylated
<p>Myristoylated AC3-I is a biologically active peptide and a myristoylated variant of the Autocamtide-3-Derived Inhibitory Peptide (AC3-I).</p>Fórmula:C78H137N21O20Pureza:98%Cor e Forma:SolidPeso molecular:1689.05BMS-906024
CAS:<p>BMS-906024 (Osugacestat) is a gamma secretase inhibitor, a Notch inhibitor.BMS-906024 has broad-spectrum antitumour activity.</p>Fórmula:C26H26F6N4O3Pureza:99.88% - >99.99%Cor e Forma:SolidPeso molecular:556.5Hydroxytacrine maleate
CAS:<p>Hydroxytacrine maleate (Velnacrine maleate) is a cholinesterase inhibitor used in the study of Alzheimer's type dementia (SDAT).</p>Fórmula:C17H18N2O5Pureza:98.84%Cor e Forma:SolidPeso molecular:330.34Trontinemab
CAS:<p>Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC).</p>Pureza:96.77% - 99%Cor e Forma:Liquid(S)-UFR2709 hydrochloride
CAS:<p>(S)-UFR2709 HCl: competitive nAChR blocker, prefers α4β2 over α7, lessens anxiety & alcohol intake in rats, studies nicotine addiction.</p>Fórmula:C13H18ClNO2Pureza:98.94%Cor e Forma:SolidPeso molecular:255.74MAO-B-IN-18
<p>MAO-B-IN-18 is a potent, selective inhibitor of MAO B, demonstrating IC50 values of 52 nM for hMAO B and 14 μM for hMAO A.</p>Fórmula:C25H22N4O5Pureza:98%Cor e Forma:SolidPeso molecular:458.47Nardoguaianone J
CAS:<p>Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].</p>Fórmula:C15H22O2Cor e Forma:SolidPeso molecular:234.33(S)-3,4-DCPG HCl
<p>(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.</p>Fórmula:C10H10ClNO6Pureza:99.53% - 99.9%Cor e Forma:SoildPeso molecular:275.64Laniquidar TFA
<p>Laniquidar TFA (R101933), a non-competitive P-gp inhibitor, has an IC50 of 0.51 μM; used to study AML and MDS, but with limited bioavailability.</p>Fórmula:C39H37F3N4O5Pureza:99.85%Cor e Forma:SoildPeso molecular:698.73Minaprine
CAS:<p>Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.</p>Fórmula:C17H22N4OPureza:98%Cor e Forma:SolidPeso molecular:298.38GluN2B receptor modulator-1
CAS:<p>GluN2B receptor modulator-1 is a selective negative allosteric modulator of NMDA receptor GluN2B subunits (IC50 31 nM), valuable for neuropharmacology studies.</p>Fórmula:C17H15F3N4O2SPureza:99.56%Cor e Forma:SolidPeso molecular:396.392,3-Dehydrosilybin A
CAS:<p>2,3-Dehydrosilybin A is a useful organic compound for research related to life sciences and the catalog number is T125202.</p>Fórmula:C25H20O10Cor e Forma:SolidPeso molecular:480.425β-Amyloid (1-20)
CAS:<p>This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.</p>Fórmula:C113H157N31O32Pureza:98%Cor e Forma:SolidPeso molecular:2461.7Tropicamide
CAS:<p>Tropicamide (Ro 1-7683), a synthetic atropine-like muscarinic antagonist, dilates pupils and paralyzes eye muscles for diagnostic use.</p>Fórmula:C17H20N2O2Pureza:99.78% - 99.94%Cor e Forma:White PowderPeso molecular:284.35VVZ-149
<p>VVZ-149 is an antagonist of both serotonin receptor 2A (5HT2A) and glycine transporter type 2 (GlyT2), with potential anti-nociceptive activity.</p>Cor e Forma:SolidAChE-IN-49
<p>AChE-IN-49 (Compd (S)-7g) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 0.0003 μM.</p>Fórmula:C31H28BrClN2O3Peso molecular:590.09718Rilmazolam
CAS:<p>Rilmazolam is a triazolobenzodiazepine compound and serves as the active metabolite of Rilmazafone.</p>Fórmula:C19H15Cl2N5OCor e Forma:SolidPeso molecular:400.26β-Amyloid (35-25)
CAS:<p>β-Amyloid (35-25) is the reverse sequence of β-Amyloid (25-35).</p>Fórmula:C45H81N13O14SPeso molecular:1060.27BuChE-IN-11
<p>BuChE-IN-11 (Compound 3b-1) is a selective inhibitor of BuChE with an IC50 of 0.44 μM for hBuChE. The compound demonstrates high brain-blood barrier permeability and possesses free radical scavenging capabilities, indicating significant antioxidant activity. BuChE-IN-11 interacts with the choline binding site, the acyl binding site, and the peripheral anionic site, showing submicromolar inhibitory activity against BuChE and preventing the self-aggregation of β-amyloid protein (Aβ). This compound holds promise for research in the field of Alzheimer's disease.</p>Fórmula:C28H27FN4O2Peso molecular:470.2118mHTT-IN-1
CAS:<p>mHTT-IN-1 is a potent inhibitor of toxic mHTT, linked to Huntington's disease, with an EC50 of 46 nM.</p>Fórmula:C18H19N7OSCor e Forma:SolidPeso molecular:381.45(S)-Vamicamide
CAS:<p>(S)-Vamicamide is an anti-anticholinergic compound.</p>Fórmula:C18H23N3OPureza:99.48% - 99.65%Cor e Forma:SoildPeso molecular:297.39RuBi-Nicotine
CAS:<p>Nicotinic receptor agonist</p>Fórmula:C40H44Cl2N8RuPureza:98%Cor e Forma:SolidPeso molecular:808.81Mesoridazine Besylate
CAS:<p>Mesoridazine Besylate (Serentil), a piperidine antipsychotic and phenothiazine, treats schizophrenia; it's a thioridazine metabolite.</p>Fórmula:C27H32N2O4S3Pureza:99.58%Cor e Forma:SolidPeso molecular:544.75Endosulfan I
CAS:<p>Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complex</p>Fórmula:C9H6Cl6O3SPureza:99.86%Cor e Forma:SolidPeso molecular:406.93Anagyrine hydrochloride
CAS:<p>Anagyrine hydrochloride, a quinolizidine from Lupinus albus, targets muscarinic/nicotinic receptors; IC50: 132/2096 µM. It desensitizes nAChR directly.</p>Fórmula:C15H21ClN2OCor e Forma:SolidPeso molecular:280.79Pirimiphos-ethyl
CAS:<p>Pirimiphos-ethyl is used as an organophosphorus pesticide.</p>Fórmula:C13H24N3O3PSPureza:98%Cor e Forma:SolidPeso molecular:333.39TC-2216
CAS:<p>TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.</p>Fórmula:C12H17N3Pureza:99.33%Cor e Forma:SolidPeso molecular:203.28(Iso)-Samixogrel
CAS:<p>(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.</p>Fórmula:C25H25ClN2O4SPureza:98.80%Cor e Forma:SolidPeso molecular:484.99Melatonin-Tamoxifen Conjugate
<p>Melatonin-Tamoxifen Conjugate (compound 16c) is an anticancer drug conjugate made of Melatonin and Tamoxifen, serving as an effective antagonist of ERα (IC50 = 863 nM). In cells expressing the hMT1 receptor, it binds to MLT receptors (Ki = 3.1 nM) and exhibits the ability to promote β-arrestin activation (EC50 = 914 nM) and ERK activation (EC50 = 98 nM). The IC50 values for Melatonin-Tamoxifen Conjugate in MCF-7, MDA-MB-231, and HT-1080 cell lines are 6.8 μM, 6.4 μM, and 1.7 μM, respectively.</p>Fórmula:C47H58N4O4Cor e Forma:SolidPeso molecular:742.99BSB
CAS:<p>BSB is a Congo red-derived fluorescent probe, an amyloid protein imaging agent, interacting with amyloid fibrils formed by Aβ (1-40) peptides in rodents.</p>Fórmula:C24H17BrO6Pureza:95.53%Cor e Forma:SolidPeso molecular:481.29(Rac)-Sabcomeline
CAS:<p>(Rac)-Sabcomeline ((Rac)-SB-202026) is an M1/M4 muscarinic agonist used in the study of neurologic disorders such as schizophrenia.</p>Fórmula:C10H15N3OPureza:99.14%Cor e Forma:SolidPeso molecular:193.25(-)-2-Phenylpropylamine
CAS:<p>(-)-2-Phenylpropylamine ((S)-2-Phenylpropylamine) (compound 3b) functions as an inhibitor for both MAO-A and MAO-B, with Ki values of 584 μM and 156 μM, respectively.</p>Fórmula:C9H13NCor e Forma:SolidPeso molecular:135.21(S)-AMPA HCl
<p>(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.</p>Fórmula:C7H11ClN2O4Pureza:99.18%Cor e Forma:SolidPeso molecular:222.63Pyrantel hydrochloride
CAS:<p>Pyrantel hydrochloride is the hydrochloride form of Pyrantel. Pyrantel is is an anthelmintic and a nicotinic acetylcholine receptor (nAChR) agonist.</p>Fórmula:C11H15ClN2SPureza:98.01%Cor e Forma:SoildPeso molecular:242.77BIBD-124
CAS:<p>BIBD-124, with an IC50 value of 9.51 nM, effectively binds to amyloid beta (Aβ) plaques.</p>Fórmula:C19H24FN3O3Cor e Forma:SolidPeso molecular:361.41Methyllycaconitine citrate
CAS:<p>Methyllycaconitine citrate (MLA) is an α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist that crosses the blood-brain barrier.</p>Fórmula:C43H58N2O17Pureza:98.03% - 98.91%Cor e Forma:SolidPeso molecular:874.92Biphenyl-3′,3,4,4′-tetrol
CAS:<p>Biphenyl-3′,3,4,4′-tetrol (BPT) is a potent inhibitor of Aβ40 aggregation and can be utilized in research related to neurodegenerative diseases such as Alzheimer's.</p>Fórmula:C12H10O4Cor e Forma:SolidPeso molecular:218.21LOX-IN-4
CAS:<p>LOX-IN-4 (Compound 112) is an inhibitor of lysyl oxidase (LOX). It holds potential for use in cancer research.</p>Fórmula:C20H24Cl2FN3O2SCor e Forma:SolidPeso molecular:460.39Glycerophosphorylethanolamine (sodium salt)
CAS:<p>Glycerophosphorylethanolamine, a phosphatidylethanolamine metabolite, elevates in Alzheimer's and promotes Aβ40 aggregation.</p>Fórmula:C5H13NNaO6PCor e Forma:SolidPeso molecular:237.12R-(+)-Cotinine
CAS:<p>R-(+)-Cotinine, an inactive nicotine metabolite, boosts Ach-induced current in human α7 nAChRs.</p>Fórmula:C10H12N2OCor e Forma:SolidPeso molecular:176.227-Methyl DMT
CAS:<p>7-Methyl DMT (7-TMT) acts as a 5-HT2 receptor agonist. Structurally, it is a tryptamine derivative and serves as an analytical reference for the psychoactive substance DOM. It is also applicable in research related to neurological disorders.</p>Fórmula:C13H18N2Cor e Forma:SolidPeso molecular:202.3Imagabalin
CAS:<p>Imagabalin is an active compound used in the study of neurological diseases.</p>Fórmula:C9H19NO2Cor e Forma:SolidPeso molecular:173.25COX-1/2-IN-4
<p>COX-1/2-IN-4 (compound 2b) is a dual COX-1 and COX-2 inhibitor with respective IC50 values of 0.239 μM for COX-1 and 0.191 μM for COX-2.</p>Fórmula:C22H24N2O2SPureza:98%Cor e Forma:SolidPeso molecular:380.5Xylamidine
CAS:<p>Xylamidine is a biochemical.</p>Fórmula:C19H24N2O2Cor e Forma:SolidPeso molecular:312.41TMPH
CAS:<p>TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.</p>Fórmula:C16H31NO2Pureza:99.78%Cor e Forma:SoildPeso molecular:269.42[Ala11,D-Leu15]-Orexin B(human)
CAS:<p>OX2 receptor agonist with 400x selectivity vs OX1. EC50: 0.13 nM (OX2), 52 nM (OX1).</p>Fórmula:C120H206N44O35SPureza:98%Cor e Forma:SolidPeso molecular:2857.28NMDA receptor antagonist 8
<p>Compound (R)-10a, an NMDA receptor antagonist, exhibits selectivity for the GluN2B subunit, possessing a Ki of 265 nM and an IC50 of 62 nM.</p>Fórmula:C22H27N3OPureza:98%Cor e Forma:SolidPeso molecular:349.47Suntinorexton
CAS:<p>Suntinorexton (TAK 861) is an orexin type 2 receptor (OX2R) agonist used in the study of neurologic disorders.</p>Fórmula:C23H28F2N2O4SPureza:99.89%Cor e Forma:SolidPeso molecular:466.54β-Amyloid (12-28)
CAS:<p>Amyloid β-peptide fragment; minimum section required to bind to brain proteins.</p>Fórmula:C89H135N25O25Pureza:98%Cor e Forma:SolidPeso molecular:1955.18TRV-7019
CAS:<p>TRV-7019: BBB-permeable radioligand for brain imaging, used in diagnosing amyloid diseases, MS, and brain tumors.</p>Fórmula:C14H12INO3Cor e Forma:SolidPeso molecular:369.15
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