Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(940 produtos)
- ACK(1 produtos)
- AChR(574 produtos)
- ATP Citrato Liase(16 produtos)
- Receptor adrenérgico(2.942 produtos)
- BACE(36 produtos)
- Beta Amilóide(204 produtos)
- CaMK(68 produtos)
- COX(562 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor GABA(336 produtos)
- Gama-secretase(59 produtos)
- GluR(255 produtos)
- GlyT(24 produtos)
- Receptor de Histamina(358 produtos)
- LRRK2(33 produtos)
- Receptor de Melatonina(24 produtos)
- NMDAR(28 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(296 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5400 produtos de "Neurociência"
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(Rac)-5-Carboxy tolterodine
CAS:<p>(Rac)-5-Carboxy tolterodine is an inactive metabolite of Tolterodine, which acts as a muscarinic acetylcholine receptor antagonist.</p>Fórmula:C22H29NO3Cor e Forma:SolidPeso molecular:355.47SSAO inhibitor-1
CAS:<p>SSAO Inhibitor-1 blocks SSAO, has anti-inflammatory effects, used in liver disease research.</p>Fórmula:C17H24FN5O2Cor e Forma:SolidPeso molecular:349.41BChE-IN-40
<p>BChE-IN-40 (compound D40) is a potent butyrylcholinesterase inhibitor with an IC50 of 0.59 μM. It demonstrates significant anti-inflammatory effects, with an IC50 of 4.55 μM in inhibiting nitric oxide production. Additionally, BChE-IN-40 exhibits excellent permeability across the blood-brain barrier.</p>Fórmula:C28H30N2O7Cor e Forma:SolidPeso molecular:506.2053Methyllycaconitine citrate
CAS:<p>Methyllycaconitine citrate (MLA) is an α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist that crosses the blood-brain barrier.</p>Fórmula:C43H58N2O17Pureza:98.03% - 98.91%Cor e Forma:SolidPeso molecular:874.92CHF-5022
CAS:<p>CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).</p>Fórmula:C17H12F4O2Cor e Forma:SolidPeso molecular:324.27Vortioxetine D8
CAS:<p>Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).</p>Fórmula:C18H22N2SPureza:98%Cor e Forma:SolidPeso molecular:306.5Epiboxidine
CAS:<p>Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.</p>Fórmula:C10H14N2OCor e Forma:SolidPeso molecular:178.23SB656104
CAS:<p>SB656104 is a bioactive chemical.</p>Fórmula:C25H30ClN3O3SCor e Forma:SolidPeso molecular:488.04isomer-Cilansetron
CAS:<p>isomer-Cilansetron is an isomer of Cilansetron.</p>Fórmula:C20H21N3OPureza:99.92% - 99.96%Cor e Forma:SoildPeso molecular:319.4Blestrin D
CAS:<p>Blestrin D: BChE mixed-type inhibitor, IC50=8.1μM, from Bletilla striata, for AD research.</p>Fórmula:C30H24O6Cor e Forma:SolidPeso molecular:480.51AChE-IN-43
<p>AChE-IN-43 is a potent, selective AChE inhibitor with a K i of 0.41 μM, applicable in the study of neurological diseases [1].</p>Cor e Forma:Odour Solidepi-Aszonalenin A
CAS:<p>epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.</p>Fórmula:C25H25N3O3Cor e Forma:SolidPeso molecular:415.48Nardoguaianone J
CAS:<p>Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].</p>Fórmula:C15H22O2Cor e Forma:SolidPeso molecular:234.33JH-XII-03-02
CAS:<p>JH-XII-03-02 is a potent and selective leucine-rich repeat kinase 2 (LRRK2) proteolysis targeting chimera (PROTAC) degrader, utilized in Parkinson's Disease (PD</p>Fórmula:C43H51N9O10Pureza:98%Cor e Forma:SolidPeso molecular:853.92Calmodulin Binding Peptide 1
CAS:<p>Calmodulin Binding Peptide 1, a high-affinity MLCK-derived inhibitor, blocks IP3-induced Ca2+ release.</p>Fórmula:C231H373N69O70S2Pureza:98%Cor e Forma:SolidPeso molecular:5301.1TIP 39, Tuberoinfundibular Neuropeptide
CAS:<p>TIP39 is a synthetic neuropeptide agonist for human and rat PTH2 receptors from the hypothalamus.</p>Fórmula:C202H325N61O54SPureza:98%Cor e Forma:SolidPeso molecular:4504.2N-Desmethyl Pimavanserin
CAS:<p>N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.</p>Fórmula:C24H32FN3O2Pureza:98.02%Cor e Forma:SolidPeso molecular:413.53VU6028418
CAS:<p>VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).</p>Cor e Forma:SolidTC-2559 difumarate
CAS:<p>TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.</p>Fórmula:C20H26N2O9Cor e Forma:SolidPeso molecular:438.43AChE-IN-40
<p>AChE-IN-40 (Compound 5C), with an inhibitory concentration 50 (IC50) of 120 nM, is an acetylcholinesterase (AChE) inhibitor suitable for Alzheimer's disease</p>Fórmula:C23H27NO4Cor e Forma:SolidPeso molecular:381.465-Hydroxymethyl tolterodine formate
CAS:<p>5-Hydroxymethyl tolterodine (formate) (PNU-200577 (formic)) is an active metabolite of the muscarinic acetylcholine receptor antagonists Tolterodine and Fesoterodine. It is synthesized by the cytochrome P450 (CYP) isoenzyme CYP2D6 and plasma esterases.</p>Fórmula:C23H33NO4Cor e Forma:SolidPeso molecular:387.51TRV-7019
CAS:<p>TRV-7019: BBB-permeable radioligand for brain imaging, used in diagnosing amyloid diseases, MS, and brain tumors.</p>Fórmula:C14H12INO3Cor e Forma:SolidPeso molecular:369.15Endosulfan I
CAS:<p>Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complex</p>Fórmula:C9H6Cl6O3SPureza:99.86%Cor e Forma:SolidPeso molecular:406.93Calmodulin-Dependent Protein Kinase II 290-309 acetate
<p>Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).</p>Fórmula:C105H189N31O26SPureza:96.7%Cor e Forma:SolidPeso molecular:2333.88JF-NP-26
<p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>Cor e Forma:SolidMaesopsin
<p>Maesopsin is a useful organic compound for research related to life sciences and the catalog number is T124581.</p>Fórmula:C15H12O6Cor e Forma:SolidPeso molecular:288.2551,8-Cineole
CAS:<p>Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.</p>Fórmula:C10H18OPureza:97.44% - 97.44%Cor e Forma:SolidPeso molecular:154.25LY-53857 free base
CAS:<p>LY-53857 free base is a bioactive chemical.</p>Fórmula:C23H32N2O3Cor e Forma:SolidPeso molecular:384.51[Ala11,D-Leu15]-Orexin B(human)
CAS:<p>OX2 receptor agonist with 400x selectivity vs OX1. EC50: 0.13 nM (OX2), 52 nM (OX1).</p>Fórmula:C120H206N44O35SPureza:98%Cor e Forma:SolidPeso molecular:2857.28Pirimiphos-ethyl
CAS:<p>Pirimiphos-ethyl is used as an organophosphorus pesticide.</p>Fórmula:C13H24N3O3PSPureza:98%Cor e Forma:SolidPeso molecular:333.39LY 293284
CAS:<p>LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.</p>Fórmula:C19H26N2OCor e Forma:SolidPeso molecular:298.42G923-0271
CAS:<p>G923-0271 is a TDP-43 inhibitor that improves disease phenotypes in TDP-43 nematode models and reduces the overexpression of human TDP-43, ALS FTD.</p>Fórmula:C28H23FN4OCor e Forma:SolidPeso molecular:450.511-Ethyl-1H-indole
CAS:<p>1-Ethyl-1H-indole exhibits inhibitory activity against AChE (IC₅₀ = 101 µM) and can be used in related research in the field of life sciences.</p>Fórmula:C10H11NPureza:98.80%Cor e Forma:SolidPeso molecular:145.2(R)-(+)-Anatabine
CAS:<p>(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent agonist of α4β2 nAChR.</p>Fórmula:C10H12N2Pureza:98%Cor e Forma:SolidPeso molecular:160.22(rel)-Asperparaline A
CAS:<p>Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.</p>Fórmula:C20H29N3O3Cor e Forma:SolidPeso molecular:359.47Neuroprotective Compound Library
<p>A unique collection of xnum bioactive small molecules with neuroprotective relevance for high throughput screening (HTS) and high content screening (HCS);</p>Cor e Forma:Odour SolidFasciculic acid B
CAS:<p>Fasciculic acid B: ester of fasciculol B, 3-hydroxy-methylglutaric acid; a calmodulin antagonist from Naematoloma fasciculare.</p>Fórmula:C36H60O9Pureza:98%Cor e Forma:SolidPeso molecular:636.86NNC 11-1607
CAS:<p>NNC 11-1607 is a functionally selective agonist of M(1)/M(4) mAChR.</p>Fórmula:C30H32N6O2S2Cor e Forma:SolidPeso molecular:572.742002-H20
CAS:<p>2002-H20 is an Aβ42-induced cytotoxicity inhibitor. It acts by binding the Alzheimer's Aβ peptide and reducing its cytotoxicity.</p>Fórmula:C20H15N3O3Pureza:98%Cor e Forma:SolidPeso molecular:345.358Substance P(1-4) Acetate
<p>Substance P(1-4) Acetate is a neurokinin receptor (NK-R) antagonist, inhibiting the formation of PV EEC.</p>Fórmula:C24H44N8O7Pureza:99.84%Cor e Forma:SolidPeso molecular:556.668-hydroxy Amoxapine
CAS:<p>8-hydroxy Amoxapine is a metabolite of the tetracyclic antidepressant amoxapine .1,2</p>Fórmula:C17H16ClN3O2Cor e Forma:SolidPeso molecular:329.78Furosemide
CAS:<p>Furosemide is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used for edema and chronic renal insufficiency.</p>Fórmula:C12H11ClN2O5SPureza:99.32% - 99.89%Cor e Forma:Crystals From Aqueous Ethanol Tasteless (Ntp 1992)Peso molecular:330.744hAChE-IN-5
<p>hAChE-IN-5 (compound 49) is a dual inhibitor of human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBuChE), exhibiting inhibitory potency with</p>Pureza:98%Cor e Forma:Odour SolidAChE-IN-35
<p>AChE-IN-35 (compound 5g) serves as an acetylcholinesterase inhibitor, exhibiting an inhibitory concentration 50 (IC50) value of 5.88 μM [1].</p>Fórmula:C20H16N8O5Cor e Forma:SolidPeso molecular:448.39Orexin B, rat, mouse
CAS:<p>Orexin B, rat, mouse is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.</p>Fórmula:C126H215N45O34SPureza:98%Cor e Forma:SolidPeso molecular:2936.45Malaoxon
CAS:<p>Malaoxon is used as an insecticide.</p>Fórmula:C10H19O7PSCor e Forma:SolidPeso molecular:314.29Flufiprole
CAS:<p>Flufiprole is used as a phenylpyrazole pesticide. It has enantioselective metabolism in human and rat liver microsomes.</p>Fórmula:C16H10Cl2F6N4OSCor e Forma:SolidPeso molecular:491.24RuBi-Nicotine
CAS:<p>Nicotinic receptor agonist</p>Fórmula:C40H44Cl2N8RuPureza:98%Cor e Forma:SolidPeso molecular:808.81STX-107
CAS:<p>STX-107 is a potent and selective mGluR5 agonist for the study of Fragile X Syndrome.</p>Fórmula:C18H10FN3SPureza:99.17%Cor e Forma:SolidPeso molecular:319.36Paecilomide
CAS:<p>Paecilomide is a pyridone alkaloid and acetylcholinesterase inhibitor [1] .</p>Fórmula:C12H15NO4Cor e Forma:SolidPeso molecular:237.25
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