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Neurociência

Neurociência

Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.

Subcategorias de "Neurociência"

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Foram encontrados 5400 produtos de "Neurociência"

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  • Lesogaberan napadisylate

    CAS:
    <p>Lesogaberan (AZD-3355) is a selective GABAB agonist with EC50 of 8.6 nM, Ki of 5.1 nM in rats, and acts peripherally on the esophageal sphincter.</p>
    Fórmula:C13H17FNO5PS
    Cor e Forma:Solid
    Peso molecular:349.31
  • DCCCyb

    CAS:
    <p>DCCCyb: oral GlyT1 inhibitor with high in vivo occupancy in rhesus monkeys, confirmed by PET tracer displacement.</p>
    Fórmula:C22H29Cl2NO3S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:458.44
  • TMPH

    CAS:
    <p>TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.</p>
    Fórmula:C16H31NO2
    Pureza:99.78%
    Cor e Forma:Soild
    Peso molecular:269.42
  • Endosulfan I

    CAS:
    <p>Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complex</p>
    Fórmula:C9H6Cl6O3S
    Pureza:99.86%
    Cor e Forma:Solid
    Peso molecular:406.93
  • Vortioxetine D8

    CAS:
    <p>Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors &amp; SERT (Ki: 15-1.6 nM).</p>
    Fórmula:C18H22N2S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:306.5
  • 8-hydroxy Amoxapine

    CAS:
    <p>8-hydroxy Amoxapine is a metabolite of the tetracyclic antidepressant amoxapine .1,2</p>
    Fórmula:C17H16ClN3O2
    Cor e Forma:Solid
    Peso molecular:329.78
  • β-Amyloid (35-42)

    CAS:
    <p>β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.</p>
    Fórmula:C33H60N8O9S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:744.94
  • β-Amyloid (13-27)

    CAS:
    <p>β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein.</p>
    Fórmula:C84H126N24O24
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1856.05
  • Antidepressant agent 5

    CAS:
    <p>Antidepressant agent 5 is a 7-substituted tetrahydroisoquinoline derivative with antidepressant activity.Antidepressant agent 5 acts similarly to magnoflorine</p>
    Fórmula:C20H25NO3
    Pureza:99.34%
    Cor e Forma:Soild
    Peso molecular:327.42
  • Calmodulin-Dependent Protein Kinase II 290-309 acetate


    <p>Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).</p>
    Fórmula:C105H189N31O26S
    Pureza:96.7%
    Cor e Forma:Solid
    Peso molecular:2333.88
  • (R)-Citalopram oxalate

    CAS:
    <p>(R)-Citalopram oxalate is a weak selective serotonin reuptake inhibitor (SSRI) that antagonises its S-isomer (escitalopram), anticonvulsant and antidepressant</p>
    Fórmula:C22H23FN2O5
    Pureza:99.76%
    Cor e Forma:White Solid
    Peso molecular:414.43
  • AChE-IN-35


    <p>AChE-IN-35 (compound 5g) serves as an acetylcholinesterase inhibitor, exhibiting an inhibitory concentration 50 (IC50) value of 5.88 μM [1].</p>
    Fórmula:C20H16N8O5
    Cor e Forma:Solid
    Peso molecular:448.39
  • SSAO inhibitor-1

    CAS:
    <p>SSAO Inhibitor-1 blocks SSAO, has anti-inflammatory effects, used in liver disease research.</p>
    Fórmula:C17H24FN5O2
    Cor e Forma:Solid
    Peso molecular:349.41
  • Muscarine

    CAS:
    <p>Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.</p>
    Fórmula:C9H20NO2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:174.26
  • Imagabalin

    CAS:
    <p>Imagabalin is an active compound used in the study of neurological diseases.</p>
    Fórmula:C9H19NO2
    Cor e Forma:Solid
    Peso molecular:173.25
  • Flufiprole

    CAS:
    <p>Flufiprole is used as a phenylpyrazole pesticide. It has enantioselective metabolism in human and rat liver microsomes.</p>
    Fórmula:C16H10Cl2F6N4OS
    Cor e Forma:Solid
    Peso molecular:491.24
  • Isonaringin

    CAS:
    <p>Isonaringin shows anti-Alzheimer’s activity by inhibiting AChE.</p>
    Fórmula:C27H32O14
    Cor e Forma:Solid
    Peso molecular:580.53
  • Lycoramine hydrobromide

    CAS:
    <p>Lycoramine is a natural alkaloid isolated from Lycoris chinensis.</p>
    Fórmula:C17H24BrNO3
    Cor e Forma:Solid
    Peso molecular:370.28
  • Nardoguaianone J

    CAS:
    <p>Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].</p>
    Fórmula:C15H22O2
    Cor e Forma:Solid
    Peso molecular:234.33
  • Blestrin D

    CAS:
    <p>Blestrin D: BChE mixed-type inhibitor, IC50=8.1μM, from Bletilla striata, for AD research.</p>
    Fórmula:C30H24O6
    Cor e Forma:Solid
    Peso molecular:480.51
  • PD25


    <p>PD25, an inhibitor of both AChE and BuChE, demonstrates inhibitory constants of hAChE IC50: 1.58 μM, eeAChE IC50: 1.63 μM, and eqBuChE IC50: 2.39 μM.</p>
    Fórmula:C25H24N2O4
    Cor e Forma:Solid
    Peso molecular:416.47
  • Heliosupine


    <p>Heliosupine is a useful organic compound for research related to life sciences and the catalog number is T125038.</p>
    Fórmula:C20H31NO7
    Cor e Forma:Solid
    Peso molecular:397.468
  • SB656104

    CAS:
    <p>SB656104 is a bioactive chemical.</p>
    Fórmula:C25H30ClN3O3S
    Cor e Forma:Solid
    Peso molecular:488.04
  • Binospirone

    CAS:
    <p>Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of movement disorders associated with neurologic dysfunction.</p>
    Fórmula:C20H26N2O4
    Pureza:97.57% - 98.96%
    Cor e Forma:Soild
    Peso molecular:358.43
  • (+)-Coclaurine hydrochloride

    CAS:
    <p>(+)-Coclaurine hydrochloride, also known as (+)-(R)-Coclaurine, is a benzyltetrahydroisoquinoline alkaloid extracted from multiple plant species.</p>
    Fórmula:C17H20ClNO3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:321.8
  • Lisuride maleate

    CAS:
    <p>Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.</p>
    Fórmula:C24H30N4O5
    Pureza:99.85%
    Cor e Forma:Solid
    Peso molecular:454.52
  • BI 1181181 MZ


    <p>BI 1181181 MZ is a potent and selective BACE1 inhibitor. BI 1181181 MZ is applicable to Alzheimer's disease research.</p>
    Fórmula:C31H37FN4O5
    Cor e Forma:Solid
    Peso molecular:564.2748
  • Lupanine hydrochloride

    CAS:
    <p>Lupanine hydrochloride, a Sparteine derivative, binds to nAChR with a Ki of 500 nM and has ganglioplegic properties.</p>
    Fórmula:C15H25ClN2O
    Cor e Forma:Solid
    Peso molecular:284.83
  • Proadrenomedullin (1-20), human

    CAS:
    <p>Endogenous peptide; agonist of MRGPRX2 (EC50=251 nM); noncompetitive inhibitor of nicotinic receptors; reduces catecholamine secretion; antihypertensive.</p>
    Fórmula:C112H178N36O27
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:2460.84
  • Crenezumab

    CAS:
    <p>Crenezumab (MABT 5102A) is a fully humanized anti-amyloid-beta antibody that binds to multiple forms of amyloid-beta (Aβ) for the study of Alzheimer's disease.</p>
    Pureza:97.5% (SDS-PAGE); 95.3% (SEC-HPLC) - 97.5% (SDS-PAGE); 95.3% (SEC-HPLC)
    Cor e Forma:Liquid
  • epi-Aszonalenin A

    CAS:
    <p>epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.</p>
    Fórmula:C25H25N3O3
    Cor e Forma:Solid
    Peso molecular:415.48
  • DSP-1053

    CAS:
    <p>Dsp-1053 is a powerful SERT (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonizing activity.</p>
    Fórmula:C26H32BrNO4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:502.44
  • ANQ-9040

    CAS:
    <p>ANQ-9040 is a nondepolarizing neuromuscular relaxant of the steroid class.</p>
    Fórmula:C36H58N2O5S
    Cor e Forma:Solid
    Peso molecular:630.92
  • Cytidine 5′-diphosphoethanolamine

    CAS:
    <p>Cytidine 5′-diphosphoethanolamine, a key intermediate in phosphatidylethanolamine synthesis, also serves as a stimulant of Ach synthesis [1].</p>
    Fórmula:C11H20N4O11P2
    Cor e Forma:Solid
    Peso molecular:446.24
  • Peptide 401

    CAS:
    <p>Peptide 401: AMP from bee/wasp venom, triggers histamine release, reduces paw swelling.</p>
    Fórmula:C110H192N40O24S4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:2587.22
  • Glycerophosphorylethanolamine (sodium salt)

    CAS:
    <p>Glycerophosphorylethanolamine, a phosphatidylethanolamine metabolite, elevates in Alzheimer's and promotes Aβ40 aggregation.</p>
    Fórmula:C5H13NNaO6P
    Cor e Forma:Solid
    Peso molecular:237.12
  • 5-methoxy-α-Ethyltryptamine

    CAS:
    <p>5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects. </p>
    Fórmula:C13H18N2O
    Pureza:98.25%
    Cor e Forma:Solid
    Peso molecular:218.29
  • VU6028418

    CAS:
    <p>VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).</p>
    Cor e Forma:Solid
  • JF-NP-26


    <p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>
    Cor e Forma:Solid
  • TRV-7019

    CAS:
    <p>TRV-7019: BBB-permeable radioligand for brain imaging, used in diagnosing amyloid diseases, MS, and brain tumors.</p>
    Fórmula:C14H12INO3
    Cor e Forma:Solid
    Peso molecular:369.15
  • LY 293284

    CAS:
    <p>LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.</p>
    Fórmula:C19H26N2O
    Cor e Forma:Solid
    Peso molecular:298.42
  • LOX-IN-4

    CAS:
    <p>LOX-IN-4 (Compound 112) is an inhibitor of lysyl oxidase (LOX). It holds potential for use in cancer research.</p>
    Fórmula:C20H24Cl2FN3O2S
    Cor e Forma:Solid
    Peso molecular:460.39
  • (Rac)-Sclerone

    CAS:
    <p>(Rac)-Sclerone, a natural product isolated from the green husk of Carya illinoinensis, exhibits significant AChE inhibition activity with an IC50 value of 192.</p>
    Fórmula:C10H10O3
    Cor e Forma:Solid
    Peso molecular:178.18
  • Camlipixant

    CAS:
    <p>Camlipixant (BLU-5937) is an orally active purine P2X3 receptor antagonist that is potent, selective and competitive.</p>
    Fórmula:C23H24F2N4O4
    Pureza:99.37%
    Cor e Forma:Soild
    Peso molecular:458.46
  • Mosapride citrate dihydrate

    CAS:
    <p>Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.</p>
    Fórmula:C27H35ClFN3O11
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:632.04
  • TAT-CN21 (scrambled)


    <p>TAT-CN21(scrambled) is a control peptide lacking specific targeting activity and serves as a negative control for TatCN21. TatCN21 is an effective and selective inhibitory peptide for calcium/calmodulin-dependent protein kinase II (CaMKII).</p>
    Cor e Forma:Odour Solid
  • STX-107

    CAS:
    <p>STX-107 is a potent and selective mGluR5 agonist for the study of Fragile X Syndrome.</p>
    Fórmula:C18H10FN3S
    Pureza:99.17%
    Cor e Forma:Solid
    Peso molecular:319.36
  • Oxotremorine

    CAS:
    <p>Oxotremorine acts as an agonist of mAChR, specifically activating the M1 and M3 acetylcholine receptors. In drug discrimination experiments with macaques, it exhibits effects similar to nicotine.</p>
    Fórmula:C12H18N2O
    Cor e Forma:Solid
    Peso molecular:206.28
  • MAO-IN-6


    <p>MAO-IN-6 (Compound 3f) is a reversible MAO-B inhibitor that can cross the blood-brain barrier, with an IC50 value of 0.09 μM. It also shows inhibitory activity against AChE and BChE, with IC50 values of 4.48 μM and 17.03 μM, respectively. MAO-IN-6 exhibits low cytotoxicity and is applicable in Alzheimer's disease research.</p>
    Fórmula:C22H14F3NO2
    Cor e Forma:Solid
    Peso molecular:381.35
  • BTMPS

    CAS:
    <p>BTMPS is a usage-dependent nicotinic antagonist capable of reducing acute withdrawal symptoms associated with morphine use.</p>
    Fórmula:C28H52N2O4
    Pureza:98.1%
    Cor e Forma:Solid
    Peso molecular:480.72