Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(942 produtos)
- ACK(1 produtos)
- AChR(575 produtos)
- ATP Citrato Liase(16 produtos)
- Receptor adrenérgico(2.946 produtos)
- BACE(36 produtos)
- Beta Amilóide(205 produtos)
- CaMK(69 produtos)
- COX(562 produtos)
- Receptor de Dopamina(408 produtos)
- Receptor GABA(336 produtos)
- Gama-secretase(59 produtos)
- GluR(255 produtos)
- GlyT(24 produtos)
- Receptor de Histamina(359 produtos)
- LRRK2(33 produtos)
- Receptor de Melatonina(24 produtos)
- NMDAR(28 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5400 produtos de "Neurociência"
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GNE-7915
CAS:<p>GNE-7915 is a highly potent, selective and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor.</p>Fórmula:C19H21F4N5O3Pureza:98% - ≥95%Cor e Forma:SolidPeso molecular:443.4TA-03
CAS:<p>TA-03 (7-Meota) is a potent inhibitor of AChE in treatment of cognitive manifestation of AD.</p>Fórmula:C14H16N2OPureza:99.22%Cor e Forma:SolidPeso molecular:228.29Xaliproden hydrochloride
CAS:<p>Xaliproden is a compound that mimics the effects of nerve growth factor and is also a serotonin 5-HT1A receptor agonist.</p>Fórmula:C24H23ClF3NPureza:99.99%Cor e Forma:SolidPeso molecular:417.89Nemifitide acetate(173240-15-8 free base)
<p>Nemifitide acetate, synthetic 5-amino acid antidepressant, has quick effect, mimics MIF.</p>Fórmula:C35H47FN10O8Pureza:97.97%Cor e Forma:SolidPeso molecular:754.85(RS)-3-Hydroxyphenylglycine
CAS:<p>(RS)-3-Hydroxyphenylglycine is a PI-linked metabotropic glutamate receptors agonist.</p>Fórmula:C8H9NO3Pureza:99.29%Cor e Forma:SolidPeso molecular:167.16FR 122047
CAS:<p>FR 122047 (1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride) is a potent and selective inhibitor of COX-1 with IC50 of 28 nM</p>Fórmula:C23H26ClN3O3SPureza:99.93%Cor e Forma:SolidPeso molecular:459.99SQ22536
CAS:<p>SQ22536, a tetrahydrofuryl adenosine analogue, inhibits adenylate cyclase in catfish and rat hepatocytes non-competitively.</p>Fórmula:C9H11N5OPureza:99.18%Cor e Forma:Off-White SolidPeso molecular:205.22Cyclopentolate Hydrochloride
CAS:<p>Cyclopentolate Hydrochloride is a muscarinic acetylcholine receptors antagonist with Kis of 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively.</p>Fórmula:C17H26ClNO3Pureza:99.91%Cor e Forma:SolidPeso molecular:327.85Autocamtide 2 TFA(129198-88-5 free base)
<p>Autocamtide 2 TFA, selective CaMKII peptide substrate, used in its activity assay.</p>Fórmula:C67H119F3N22O22Pureza:98%Cor e Forma:SolidPeso molecular:1641.79SAX-187
CAS:<p>SAX-187 (SAX-187) has high-affinity binding at the human 5-HT6 receptor.</p>Fórmula:C15H13ClN4O2S2Pureza:97.82% - 98%Cor e Forma:SolidPeso molecular:380.87U93631
CAS:<p>GABAA antagonist; binds picrotoxin site, stabilizes inactive channel. Speeds GABA-induced Cl- decay, minor peak effect. Inhibits 5-HT3A receptors.</p>Fórmula:C17H21N3O2Pureza:99.65% - 99.76%Cor e Forma:SolidPeso molecular:299.37Pimavanserin
CAS:<p>Pimavanserin is a potent 5-HT2A inverse agonist, used to treat Parkinson's psychosis.</p>Fórmula:C25H34FN3O2Pureza:97.84% - 99.69%Cor e Forma:Pale Yellow To Pale Orange SolidPeso molecular:427.55Bestim
CAS:<p>Bestim is an immunomodulatory dipeptide that is synthetic.</p>Fórmula:C16H19N3O5Pureza:99.76%Cor e Forma:SolidPeso molecular:333.34MK-3697
CAS:<p>MK-3697, an isonicotinamide small molecule, acts as a potent and selective Orexin 2 receptor antagonist (Ki: 0.95 nM).</p>Fórmula:C23H21N5O3SPureza:97.69% - 98.15%Cor e Forma:SolidPeso molecular:447.51LY2119620
CAS:<p>LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors.</p>Fórmula:C19H24ClN5O3SPureza:99.7%Cor e Forma:SolidPeso molecular:437.94Brexpiprazole
CAS:<p>Brexpiprazole (OPC-34712) is a partial agonist of human 5-hydroxytryptamine (5-HT) 5-HT1A and dopamine D2 receptors.</p>Fórmula:C25H27N3O2SPureza:99.06% - 99.96%Cor e Forma:SolidPeso molecular:433.57Oxyphenonium bromide
CAS:<p>Oxyphenonium bromide is an anticholinergic used to study and treat ulcers and relieve visceral spasms.</p>Fórmula:C21H34BrNO3Pureza:98.96%Cor e Forma:SolidPeso molecular:428.404Eliprodil
CAS:<p>Eliprodil (SL-820715), NR2B-NMDA receptor blocker (IC50: 1 uM), less potent on NR2A/NR2C (IC50>100 uM), explored for Parkinson's and movement issues.</p>Fórmula:C20H23ClFNOPureza:99.53% - 99.77%Cor e Forma:SolidPeso molecular:347.85Zotepine
CAS:<p>Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM,</p>Fórmula:C18H18ClNOSPureza:99.78%Cor e Forma:SolidPeso molecular:331.86CFMTI
CAS:<p>CFMTI: potent mGluR1 allosteric antagonist, 2000x selectivity over mGluR5, IC50: 2.6 nM.</p>Fórmula:C19H16FN5OPureza:97.23%Cor e Forma:SolidPeso molecular:349.36Propyphenazone
CAS:<p>Propyphenazone: an anti-inflammatory, analgesic, antipyretic pyrazolone; prodrug; COX-2 inhibitor.</p>Fórmula:C14H18N2OPureza:99.64%Cor e Forma:SolidPeso molecular:230.31Cariprazine
CAS:<p>Cariprazine (RGH-188) is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate</p>Fórmula:C21H32Cl2N4OPureza:99.68% - 99.87%Cor e Forma:SolidPeso molecular:427.41Donitriptan Mesylate
CAS:<p>Donitriptan Mesylate, a 5-HT1B/1D agonist, is used potentially for the treatment of migraines.</p>Fórmula:C24H29N5O5SCor e Forma:SolidPeso molecular:499.58SB-203186 hydrochloride
CAS:<p>SB 203186 hydrochloride is a potent 5-HT4 receptor antagonist</p>Fórmula:C16H20N2O2·HClPureza:99.64%Cor e Forma:SolidPeso molecular:308.81Zaltoprofen
CAS:<p>Zaltoprofen (Soleton) is a Cox-1 and Cox-2 inhibitor, which is used for the treatment of arthritis.</p>Fórmula:C17H14O3SPureza:99.72%Cor e Forma:Off-White To Pale Yellow Crystalline SolidPeso molecular:298.36Homocarnosine acetate
<p>Homocarnosine acetate is a dipeptide unique to brain consisting of γ-aminobutyric acid (GABA) and histidine.</p>Fórmula:C12H20N4O5Pureza:99.52%Cor e Forma:SolidPeso molecular:300.31MTEP
CAS:<p>MTEP: potent, selective mGluR5 antagonist; IC50=5 nM, Ki=16 nM; may have antidepressant/anxiolytic effects; useful in Parkinson's research.</p>Fórmula:C11H8N2SCor e Forma:SolidPeso molecular:200.26Ocaperidone
CAS:<p>Ocaperidona (Ocaperidone (Ocaperidona)), a very high affinity dopamine D2 antagonist.</p>Fórmula:C24H25FN4O2Pureza:99.33%Cor e Forma:SolidPeso molecular:420.48SCH-23390 hydrochloride
CAS:<p>SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).</p>Fórmula:C17H19Cl2NOPureza:98% - 99.83%Cor e Forma:SolidPeso molecular:324.24Ipratropium Bromide
CAS:<p>Ipratropium Bromide (Sch 1000) is an antagonist of muscarinic receptors and is used in COPD and asthma studies.</p>Fórmula:C20H30BrNO3Pureza:99.92%Cor e Forma:SolidPeso molecular:412.37Aripiprazole monohydrate
CAS:<p>Aripiprazole (OPC-14597) is a potent D2 partial agonist and inverse agonist of 5-HT2 receptors, used for schizophrenia and COVID-19 studies.</p>Fórmula:C23H29Cl2N3O3Cor e Forma:SolidPeso molecular:466.4KN-62
CAS:<p>KN-62 is a potent and specific Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with Ki of 0.9 μM.</p>Fórmula:C38H35N5O6S2Pureza:99.80% - >99.99%Cor e Forma:White SolidPeso molecular:721.84VU 0238429
CAS:<p>VU 0238429 (SCR-1481B1) is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).</p>Fórmula:C17H12F3NO4Pureza:>99.99%Cor e Forma:SolidPeso molecular:351.28RS-127445
CAS:<p>RS-127445 (MT500) is a selective 5-HT2B receptor antagonist with pKi of 9.5 and pIC50 of 10.4, exhibits >1000-fold selectivity against other 5-HT receptors.</p>Fórmula:C17H16FN3Pureza:99.32%Cor e Forma:SolidPeso molecular:281.33JH-II-127
CAS:<p>JH-II-127 is an oral LRRK2 inhibitor with IC50s: 6.6 nM (WT), 2.2 nM (G2019S), 47.7 nM (A2016T).</p>Fórmula:C19H21ClN6O3Pureza:98.32%Cor e Forma:SolidPeso molecular:416.86Melitracen
CAS:<p>Melitracen is a tricyclic antidepressant.</p>Fórmula:C21H25NCor e Forma:SolidPeso molecular:291.43Tiagabine hydrochloride hydrate
CAS:<p>Tiagabine HCl hydrate, IC50: 67-446 nM, selectively inhibits GABA uptake, acts as an anticonvulsant.</p>Fórmula:C20H28ClNO3S2Cor e Forma:SolidPeso molecular:430.02Medetomidine hydrochloride
CAS:<p>Medetomidine hydrochloride (MPV785) is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.</p>Fórmula:C13H16N2·HClPureza:99.96%Cor e Forma:White Or Off White Crystalline PowderPeso molecular:236.74NAN-190 hydrobromide
CAS:<p>NAN-190 hydrobromide is an antagonist of serotonin receptor 5-HT.</p>Fórmula:C23H28BrN3O3Pureza:95.20%Cor e Forma:SolidPeso molecular:474.39Eliapixant
CAS:<p>Eliapixant (BAY 1817080) is a selective P2X3 antagonist with an 8 nM IC50, used for refractory chronic cough research.</p>Fórmula:C22H21F3N4O3SPureza:99.86%Cor e Forma:SolidPeso molecular:478.49VU 0364439
CAS:<p>VU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM).</p>Fórmula:C18H13Cl2N3O3SPureza:97.9%Cor e Forma:SolidPeso molecular:422.29Pimavanserin tartrate
CAS:<p>Pimavanserin tartrate is a potent 5-HT 2A receptor inverse agonist used to treat Parkinson's disease-related psychosis.Cost-effective and quality-assured.</p>Fórmula:C50H68F2N6O4·C4H6O6Pureza:99.24% - 99.98%Cor e Forma:SolidPeso molecular:1005.2ML380
CAS:<p>ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).</p>Fórmula:C23H25F3N4O3SPureza:99.69%Cor e Forma:SolidPeso molecular:494.53LRRK2-IN-1
CAS:<p>LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.</p>Fórmula:C31H38N8O3Pureza:98% - 98.82%Cor e Forma:SolidPeso molecular:570.692'MeO6MF
CAS:<p>2'MeO6MF is a brain-penetrant positive allosteric modulator at α2β1γ2L and all α1-containing GABAA receptors.It offers neuroprotection and improved functional</p>Fórmula:C17H14O3Pureza:99.28% - 99.63%Cor e Forma:SolidPeso molecular:266.29Autocamtide-2-related inhibitory peptide
CAS:<p>Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.</p>Fórmula:C64H116N22O19Pureza:>99.99%Cor e Forma:SolidPeso molecular:1497.74FTIDC
CAS:<p>FTIDC: potent, selective mGluR1 allosteric antagonist, weak on mGluR5. IC50: human 5.8 nM, mouse 3.1 nM. Noncompetitive.</p>Fórmula:C18H23FN6OPureza:94.58%Cor e Forma:SolidPeso molecular:358.41RAGE antagonist peptide acetate
<p>RAGE antagonist peptide acetate blocks RAGE-ligands like HMGB-1, has anti-tumor, and anti-inflammatory effects.</p>Fórmula:C59H105N13O19SPureza:97.17%Cor e Forma:SolidPeso molecular:1332.61Tandospirone hydrochloride
CAS:<p>Tandospirone (SM-3997) HCl: potent 5-HT1A partial agonist; Ki: 27 nM; anxiolytic, antidepressant, for CNS disorder research.</p>Fórmula:C21H30ClN5O2Cor e Forma:SolidPeso molecular:419.95Perospirone hydrochloride
CAS:<p>Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia.</p>Fórmula:C23H31ClN4O2SPureza:99.37%Cor e Forma:White SolidPeso molecular:463
