Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(648 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.029 produtos)
- BACE(37 produtos)
- Beta Amilóide(231 produtos)
- CaMK(73 produtos)
- COX(602 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(372 produtos)
- Gama-secretase(63 produtos)
- GluR(265 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(42 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(42 produtos)
- Receptor opioide(327 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5636 produtos de "Neurociência"
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Fasciculic acid A
CAS:Fasciculic acid A is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.Fórmula:C36H60O8Cor e Forma:SolidPeso molecular:620.868CPN-219
CAS:CPN-219 is a next-generation hexapeptidic NMUR2 agonist that selectively and dose-dependently activates NMUR2, exhibiting an EC50 value of 2.2 nM [1].Fórmula:C40H72N12O8Peso molecular:849.08Pseudocoptisine acetate
CAS:Pseudocoptisine acetate is a quaternary alkaloid isolated from the tubers of Corydalis turtschaninovii,with anti-inflammatory properties.Fórmula:C21H17NO6Pureza:98%Cor e Forma:SolidPeso molecular:379.36DD205-291
CAS:DD205-291 is an orally active PROTAC HPK1 degrader with a DC50 of 5.3 nM. It inhibits SLP-76 phosphorylation and induces IL-2 and IFN-γ.Fórmula:C38H38ClF3N10O3Cor e Forma:SolidPeso molecular:775.22Tampramine
CAS:Tampramine: a TCA and selective norepinephrine inhibitor, with low affinity for other receptors, potential treatment for FST depression.
Fórmula:C23H24N4Pureza:99.87%Cor e Forma:SolidPeso molecular:356.46Fluphenazine-N-2-chloroethane (hydrochloride)
CAS:Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.Fórmula:C22H27Cl3F3N3SCor e Forma:SolidPeso molecular:528.89α-Casozepine
CAS:α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.Fórmula:C60H94N14O16Cor e Forma:SolidPeso molecular:1267.47Asenapine citrate
CAS:Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).Fórmula:C23H24ClNO8Cor e Forma:SolidPeso molecular:477.89Lesogaberan napadisylate
CAS:Lesogaberan (AZD-3355) is a selective GABAB agonist with EC50 of 8.6 nM, Ki of 5.1 nM in rats, and acts peripherally on the esophageal sphincter.Fórmula:C13H17FNO5PSCor e Forma:SolidPeso molecular:349.31Lupanine hydrochloride
CAS:Lupanine hydrochloride, a Sparteine derivative, binds to nAChR with a Ki of 500 nM and has ganglioplegic properties.Fórmula:C15H25ClN2OCor e Forma:SolidPeso molecular:284.83TAT-CN21
TatCN21, with an IC 50 of 77 nM, serves as a potent and selective inhibitor peptide of the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase. It is particularly useful in research pertaining to ischemia and neurodegenerative diseases.Fórmula:C169H303N69O43Cor e Forma:SolidPeso molecular:3989.65α-Conotoxin EI
CAS:Selective antagonist of neuromuscular nicotinic receptors α1β1γδFórmula:C83H125N27O27S5Pureza:98%Cor e Forma:SolidPeso molecular:2093.37β-Amyloid (35-42)
CAS:β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.Fórmula:C33H60N8O9SPureza:98%Cor e Forma:SolidPeso molecular:744.94Brexpiprazole S-oxide D8
CAS:Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.Fórmula:C25H19D8N3O3SPureza:98%Cor e Forma:SolidPeso molecular:457.61Vortioxetine D8
CAS:Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).Fórmula:C18H22N2SPureza:98%Cor e Forma:SolidPeso molecular:306.5SB236057
CAS:SB236057: potent selective inverse agonist at 5-HT autoreceptors; increases brain 5-HT; teratogen causing musculoskeletal defects in rodents.Fórmula:C33H34N4O3Pureza:98%Cor e Forma:SolidPeso molecular:534.65Cevimeline hydrochloride hemihydrate
CAS:Cevimeline hydrochloride hemihydrate is a novel muscarinic receptor agonist, used as a candidate therapeutic drug for xerostomia in Sjogren's syndrome.
Fórmula:C20H38Cl2N2O3S2Pureza:97.00%Cor e Forma:SolidPeso molecular:489.55Triazolomethylindole-3-acetic acid
CAS:Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.Fórmula:C13H12N4O2Cor e Forma:SolidPeso molecular:256.26SSAO inhibitor-1
CAS:SSAO Inhibitor-1 blocks SSAO, has anti-inflammatory effects, used in liver disease research.Fórmula:C17H24FN5O2Cor e Forma:SolidPeso molecular:349.41KGP-25
KGP-25 is an inhibitor of the voltage-gated sodium channel 1.8 (Nav1.8), utilized for analgesia by targeting the peripheral nervous system (PNS). Additionally, it targets the γ-aminobutyric acid subtype A receptor (GABAA) in the central nervous system (CNS) for use as a general anesthetic.Cor e Forma:Odour Solidβ-Amyloid (29-40)
CAS:β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical propertiesFórmula:C49H88N12O13SPureza:98%Cor e Forma:SolidPeso molecular:1085.36epi-Aszonalenin A
CAS:epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.Fórmula:C25H25N3O3Cor e Forma:SolidPeso molecular:415.48SB656104
CAS:SB656104 is a bioactive chemical.Fórmula:C25H30ClN3O3SCor e Forma:SolidPeso molecular:488.04hAChE/hBuChE-IN-1
hAChE/hBuChE-IN-1 (compound C2) acts as a dual inhibitor of cholinesterases, exhibiting IC50 values of 514 nM for hAChE and 358 nM for hBuChE. It is orally active and capable of enhancing cognitive function and spatial memory.Fórmula:C30H31FN2O3Cor e Forma:SolidPeso molecular:486.577Nardoguaianone J
CAS:Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].Fórmula:C15H22O2Cor e Forma:SolidPeso molecular:234.33Blestrin D
CAS:Blestrin D: BChE mixed-type inhibitor, IC50=8.1μM, from Bletilla striata, for AD research.Fórmula:C30H24O6Cor e Forma:SolidPeso molecular:480.51Fentonium bromide
CAS:Fentonium bromide is a biochemical.Fórmula:C31H34BrNO4Cor e Forma:SolidPeso molecular:564.51Zicronapine fumarate
CAS:Zicronapine fumarate, an antipsychotic, targets D1/D2 & 5-HT2A receptors; may treat neuropsychiatric conditions.Fórmula:C26H31ClN2O4Cor e Forma:SolidPeso molecular:470.994-Methylamphetamine hydrochloride
CAS:4-Methylamphetamine hydrochloride is a 5-HT1A receptor agonist that induces a decrease in body temperature in rats by binding to the 5-HT1A receptor. Additionally, it increases the extracellular levels of neurotransmitters norepinephrine (NE), dopamine (DA), and serotonin (5-HT) by affecting their transporters. 4-Methylamphetamine hydrochloride is applicable in the study of neurological disorders.Fórmula:C10H16ClNCor e Forma:SolidPeso molecular:185.69AChE/BuChE-IN-6
AChE/BuChE-IN-6 (Compound 11f) is an inhibitor of AChE and BuChE, with IC50 values of 1.24 and 1.85 μg/mL, respectively. It exhibits strong DPPH radical scavenging activity (IC50 = 3.15 μg/mL). In vivo toxicity studies demonstrate that AChE/BuChE-IN-6 is safe, showing no significant differences in blood and biochemical parameters compared to controls, and no abnormalities in liver and kidney tissues. This compound shows potential for Alzheimer's disease research.Fórmula:C24H20ClN3O3Cor e Forma:SolidPeso molecular:433.887LY 293284
CAS:LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.Fórmula:C19H26N2OCor e Forma:SolidPeso molecular:298.42Oxatomide
CAS:Oxatomide: Dual H1/P2X7 antagonist, antihistamine, anti-allergic, treats immune diseases, IC50: 0.95 μM (P2X7), 0.43 μM (5-HT).Fórmula:C27H30N4OPureza:99.28% - 99.72%Cor e Forma:White PowderPeso molecular:426.55Ref: TM-T19839
1mg35,00€5mg75,00€1mL*10mM (DMSO)84,00€10mg114,00€25mg222,00€50mg356,00€100mg557,00€500mg1.153,00€JF-NP-26
Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.Cor e Forma:SolidVU6028418
CAS:VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).Fórmula:C23H27F3N4OCor e Forma:SolidPeso molecular:432.491Bencycloquidium Bromide
CAS:Bencycloquidium bromide is an M3 muscarinic antagonist that reduces nasal secretion in allergic rhinitis and has high affinity for M3 receptors.Fórmula:C21H32BrNO2Cor e Forma:SolidPeso molecular:410.39TRV-7019
CAS:TRV-7019: BBB-permeable radioligand for brain imaging, used in diagnosing amyloid diseases, MS, and brain tumors.Fórmula:C14H12INO3Cor e Forma:SolidPeso molecular:369.15(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS:(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.Fórmula:C6H11NO2Cor e Forma:SolidPeso molecular:129.16Fasciculic acid B
CAS:Fasciculic acid B: ester of fasciculol B, 3-hydroxy-methylglutaric acid; a calmodulin antagonist from Naematoloma fasciculare.Fórmula:C36H60O9Pureza:98%Cor e Forma:SolidPeso molecular:636.86[Ala11,D-Leu15]-Orexin B(human)
CAS:OX2 receptor agonist with 400x selectivity vs OX1. EC50: 0.13 nM (OX2), 52 nM (OX1).Fórmula:C120H206N44O35SPureza:98%Cor e Forma:SolidPeso molecular:2857.28Imidafenacin Metabolite M4
CAS:Imidafenacin M4 is a CYP3A4-formed metabolite of the muscarinic antagonist imidafenacin.Fórmula:C18H19N3O3Cor e Forma:SolidPeso molecular:325.368(R)-(+)-Anatabine
CAS:(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent agonist of α4β2 nAChR.Fórmula:C10H12N2Pureza:98%Cor e Forma:SolidPeso molecular:160.22Dehydrodiscretamine chloride
CAS:Dehydrodiscretamine chloride, a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibits IC50 values of 17.8 μM and 118.8 μM,Fórmula:C19H18ClNO4Cor e Forma:SolidPeso molecular:359.8N-desmethyl Zolmitriptan
CAS:DZT, an active metabolite of zolmitriptan, agonizes 5-HT1B/D receptors; contracts human cerebral arteries (EC50=100nM).Fórmula:C15H19N3O2Cor e Forma:SolidPeso molecular:273.33Heliosupine
Heliosupine is a useful organic compound for research related to life sciences and the catalog number is T125038.Fórmula:C20H31NO7Cor e Forma:SolidPeso molecular:397.468Monoamine oxidase
CAS:Enzyme that breaks down amines in the brain and body, affecting mood and brain function.Cor e Forma:SolidSPL-707
CAS:SPL-707 is an effective and selective signal peptide peptidase-like 2a inhibitor (IC50: 80 nM).Fórmula:C27H28FN5O4Pureza:98%Cor e Forma:SolidPeso molecular:505.54LP 12 hydrochloride
CAS:LP 12 hydrochloride is a selective 5-HT7 receptor agonist (Ki=0.13 nM).Fórmula:C32H40ClN3OCor e Forma:SolidPeso molecular:518.144-Methoxyphenyl isothiocyanate
CAS:4-Methoxyphenyl isothiocyanate (4-Methylphenyl ITC) is recognized as an antioxidant demonstrating an IC50 of 1.25 mM for scavenging DPPH free radicals. Its antioxidant capacity, as shown by the ORAC test, is 11.7 mM TE, equivalent to the efficacy of 11.7 mmol Trolox under similar conditions. Additionally, it extends the oxidation process in the Briggs–Rauscher reaction by approximately 9180 seconds. The compound also exhibits moderate cholinesterase inhibitory activity, with an inhibition rate of 30.4% for acetylcholinesterase (AChE) and 17.9% for butyrylcholinesterase (BChE). Research suggests 4-Methoxyphenyl isothiocyanate holds promise for applications in antioxidant and neurological disorder studies.Fórmula:C8H7NOSCor e Forma:SolidPeso molecular:165.21AMI-193
CAS:AMI-193 (Spiramide) is a selective 5-HT2 & D2 receptor antagonist with antipsychotic properties.Fórmula:C22H26FN3O2Pureza:99.65%Cor e Forma:SolidPeso molecular:383.46RuBi-GABA
CAS:Ruthenium-bipyridine-triphenylphosphine caged GABAFórmula:C42H39F6N5O2P2RuPureza:98%Cor e Forma:SolidPeso molecular:922.8
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