Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(647 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.028 produtos)
- BACE(37 produtos)
- Beta Amilóide(231 produtos)
- CaMK(73 produtos)
- COX(602 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(373 produtos)
- Gama-secretase(62 produtos)
- GluR(265 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(42 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(41 produtos)
- Receptor opioide(327 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5638 produtos de "Neurociência"
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Calmodulin Kinase IINtide, Myristoylated
Myristoylated Calmodulin Kinase IINtide (Myr-CaMKIINtide) serves as a selective and noncompetitive inhibitor of CaMKII [1].Fórmula:C156H275N47O43Pureza:98%Cor e Forma:SolidPeso molecular:3497.14COX-2-IN-33
COX-2-IN-33 (compound 5f) is a selective COX-2 inhibitor with an IC50 value of 45.5 nM and exhibits potential as an anti-inflammatory agent.Fórmula:C20H13ClF3N5O4Pureza:98%Cor e Forma:SolidPeso molecular:479.8Guvacine hydrobromide
CAS:Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake.Fórmula:C6H10BrNO2Pureza:98%Cor e Forma:SolidPeso molecular:208.05Methyllycaconitine citrate
CAS:Methyllycaconitine citrate (MLA) is an α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist that crosses the blood-brain barrier.Fórmula:C43H58N2O17Pureza:98.03% - 98.91%Cor e Forma:SolidPeso molecular:874.92Hydroxytacrine maleate
CAS:Hydroxytacrine maleate (Velnacrine maleate) is a cholinesterase inhibitor used in the study of Alzheimer's type dementia (SDAT).Fórmula:C17H18N2O5Pureza:98.84%Cor e Forma:SolidPeso molecular:330.34Binospirone
CAS:Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of movement disorders associated with neurologic dysfunction.Fórmula:C20H26N2O4Pureza:97.57% - 98.96%Cor e Forma:SoildPeso molecular:358.43Ref: TM-T71138L
1mL*10mM (DMSO)33,00€1mg109,00€5mg261,00€10mg374,00€25mg583,00€50mg803,00€100mg1.063,00€200mg1.459,00€Org 13011
CAS:Org 13011 has CNS activity and induces conditioned taste aversion by mediating 5-HT 1A receptors.Fórmula:C18H25F3N4OPureza:98.02%Cor e Forma:SoildPeso molecular:370.41Ref: TM-T28258L
1mg109,00€5mg261,00€1mL*10mM (DMSO)266,00€10mg374,00€25mg583,00€50mg803,00€100mg1.063,00€200mg1.431,00€SIB 1553A
CAS:SIB 1553A is an agonist of nAChRs, a cognitive enhancer that can be used to study diseases associated with neurodegeneration.Fórmula:C13H19NOSPureza:99.79%Cor e Forma:SoildPeso molecular:237.36RS 56812
CAS:RS 56812 is a 5-HT3 receptor antagonist and agonist used in the study of cognitive disorders.Fórmula:C18H21N3O2Pureza:99.38%Cor e Forma:SoildPeso molecular:311.38AL 34662
CAS:AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also aFórmula:C10H13N3OPureza:99.97%Cor e Forma:SolidPeso molecular:191.23Methoxy-X04
CAS:Methoxy-X04, a derivative of Congo red and Chrysamine-G, is a brain-permeable fluorescent probe for amyloid-β (Aβ).
Fórmula:C23H20O3Pureza:98.96%Cor e Forma:SolidPeso molecular:344.4Profenofos
CAS:Profenofos is an organophosphate insecticide used in cotton and vegetables. that causes neurotoxicity through the inhibition of AChE activity.Fórmula:C11H15BrClO3PSPureza:97.04% - 97.24%Cor e Forma:SolidPeso molecular:373.63Encecalinol
CAS:Encecalinol, a compound isolated from the aerial parts of Ageratina grandifolia, acts as a potent inhibitor of calmodulin [1].Fórmula:C14H18O3Cor e Forma:SolidPeso molecular:234.29Arotinolol hydrochloride
CAS:Arotinolol HCl is a non-selective α/β-blocker, anti-hypertensive, anti-obesity, and improves aortic stiffness.Fórmula:C15H22ClN3O2S3Pureza:99.82%Cor e Forma:SolidPeso molecular:408SB 699551
CAS:SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.Fórmula:C34H45N3OPureza:99.83%Cor e Forma:SoildPeso molecular:511.74Ref: TM-T23325L
1mg190,00€5mg471,00€10mg662,00€25mg1.036,00€50mg1.429,00€100mg1.821,00€200mg2.489,00€NMDA receptor antagonist 6
NMDA Receptor Antagonist 6 (Compound 13b) functions as an antagonist at the glycine-binding site of the NMDA receptor and demonstrates cytoneuroprotectiveFórmula:C25H23NO2Pureza:98%Cor e Forma:SolidPeso molecular:369.46Sandaracopimaric acid
CAS:Sandaracopimaric acid, an anti-inflammatory diterpene, relaxes pulmonary arteries with an EC50 of 43.93 μM.Fórmula:C20H30O2Cor e Forma:SolidPeso molecular:302.45MR33317
MR33317 is an inhibitor of acetylcholinesterase with an IC50 value of 41 nM. Additionally, it acts as an agonist for brain 5-HT4 receptors.Fórmula:C22H28ClN3O2Peso molecular:401.187β-Amyloid (22-40)
CAS:This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein.Fórmula:C78H135N21O26SPureza:98%Cor e Forma:SolidPeso molecular:1815.1I2-IRs ligand-1
I2-IRs ligand-1 (Compound 12d) is an orally active compound capable of crossing the blood-brain barrier. It exhibits high affinity for imidazoline I2 receptors (I2-IRs) with a pKi of 9.98. This compound can enhance cognitive deficits in aging mice and possesses analgesic, anti-inflammatory, and neuroprotective properties. I2-IRs ligand-1 is applicable for research in Alzheimer's disease and related pain disorders.Fórmula:C21H23ClFN2O4PCor e Forma:SolidPeso molecular:452.845-HT5AR/5-HT6R ligand-1
5-HT5AR/5-HT6R ligand-1 (Compound PP10) is a ligand for serotonin receptors, exhibiting high affinity for the 5-HT5A and 5-HT6 receptors with Ki values of 59 nM and 96 nM, respectively. It possesses some antiproliferative activity against tumor cells and can be utilized in cancer research.Fórmula:C25H30N4O2SCor e Forma:SolidPeso molecular:450.6MGS0274
CAS:MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.Fórmula:C21H32FNO7Cor e Forma:SolidPeso molecular:429.485(Iso)-Atagabalin HCl
CAS:(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.Fórmula:C10H20ClNO2Pureza:99.88% - >99.99%Cor e Forma:SoildPeso molecular:221.72AChE/BChE-IN-20
AChE/BChE-IN-20 (compound 3m) serves as an inhibitor for both acetylcholinesterase (AChE, IC50=34.81 µM) and butyrylcholinesterase (BChE, IC50=20.66 µM). The affinity for the critical enzyme pockets and the favorable interaction profiles were established through molecular docking and kinetics simulation, making it relevant for the study of Alzheimer's disease.Cor e Forma:Odour SolidNictide
CAS:Nictide, a peptide substrate for LRRK2 (leucine-rich repeat protein kinase-2), undergoes phosphorylation by the activated form of LRRK2[G2019S], exhibiting a Km value of 10 μM.Fórmula:C123H193N45O28Cor e Forma:SolidPeso molecular:2750.13Lysyl hydroxylase 2-IN-2
Lysyl Hydroxylase 2-IN-2 (compound 13) is a potent inhibitor of Lysyl Hydroxylase 2 (LH2), exhibiting an IC50 of approximately 500 nM.Fórmula:C19H21N3O2Pureza:98%Cor e Forma:SolidPeso molecular:323.39MmTx2 toxin
MmTx2 toxin, extracted from the venom of the coral snake, serves as a modulator of the GABA A receptor, increasing its responsiveness to agonists.Fórmula:C295H450N94O97S10Pureza:98%Cor e Forma:SolidPeso molecular:7185.95PZ-1922
PZ-1922 (Compound 16), able to cross the blood-brain barrier, is a dual antagonist for 5-HT6R and 5-HT3R with K i values of 17 nM and 0.45 nM, respectively.Pureza:98%Cor e Forma:Odour SolidSCH-900229
CAS:SCH-900229, a potent presenilin 1 selective γ-secretase inhibitor, used to treat Alzheimer’s Disease.Fórmula:C21H21ClF2O6S2Cor e Forma:SolidPeso molecular:506.97Isobutyryl-L-carnitine
CAS:Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.Fórmula:C11H21NO4Pureza:98%Cor e Forma:SolidPeso molecular:231.29N-desmethyl Zolmitriptan
CAS:DZT, an active metabolite of zolmitriptan, agonizes 5-HT1B/D receptors; contracts human cerebral arteries (EC50=100nM).Fórmula:C15H19N3O2Cor e Forma:SolidPeso molecular:273.33FGIN-1-43
CAS:FGIN-1-43 is a potent and specific ligand for the mitochondrial DBI receptor.Fórmula:C28H36Cl2N2OPureza:99.57%Cor e Forma:SolidPeso molecular:487.5(+)-Coclaurine hydrochloride
CAS:(+)-Coclaurine hydrochloride, also known as (+)-(R)-Coclaurine, is a benzyltetrahydroisoquinoline alkaloid extracted from multiple plant species.Fórmula:C17H20ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:321.8FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)
FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium) is a FITC-labeled amyloid beta monomer, Alzheimer’s research, drug screening, and biomolecular studies.Fórmula:C227H330N58O66S2Cor e Forma:SolidPeso molecular:4991.53Methyl piperate
CAS:Methylpiperic acid, a piperine alkaloid, exhibits potent inhibitory activity on monoamine oxidase (MAO), with differing efficacy on isoforms: greater inhibitionFórmula:C13H12O4Pureza:98%Cor e Forma:SolidPeso molecular:232.23CPN-267 TFA
CPN-267 (compound 7b) TFA is a selective agonist of neuromedin U receptor 1 (NMUR1) with an EC50 of 0.25 nM. This compound inhibits weight gain in mice and is applicable in obesity research.Fórmula:C54H68F6N16O12SCor e Forma:SolidPeso molecular:1279.27(Glu20)-Amyloid β-Protein (1-42)
CAS:(Glu20)-Amyloid β-Protein (1-42) represents a variant of amyloid β-protein (Aβ) that fibrillizes more slowly.Fórmula:C199H309N55O62SCor e Forma:SolidPeso molecular:4495.98β-Amyloid (25-35) acetate
β-Amyloid (25-35) acetate is the Aβ(25-35) fragment of amyloid beta peptide, neurotoxicity, construct Alzheimer's disease cell and animal models.Pureza:98.26%GABAA receptor modulator-3
GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.Fórmula:C18H22O2Cor e Forma:SolidPeso molecular:270.37Lysyl hydroxylase 2-IN-1
"Lysyl Hydroxylase 2-IN-1 (compound 12) is a selective inhibitor of lysyl hydroxylase 2 (LH2) with an IC50 of approximately 300 nM and demonstrates specificityFórmula:C18H18N2O3Pureza:98%Cor e Forma:SolidPeso molecular:310.35PSEM 308 hydrochloride
PSAM agonist targeting PSAML141F-GlyR and related ion channels in mice; ideal concentration ≤5 mg/kg; plasmids at Addgene.Cor e Forma:SolidLesogaberan napadisylate
CAS:Lesogaberan (AZD-3355) is a selective GABAB agonist with EC50 of 8.6 nM, Ki of 5.1 nM in rats, and acts peripherally on the esophageal sphincter.Fórmula:C13H17FNO5PSCor e Forma:SolidPeso molecular:349.31meta-Fluoxetine (hydrochloride)
CAS:meta-Fluoxetine (hydrochloride) can be used in related research in the field of life sciences. Its product number is T37474 and CAS number is 79088-29-2.Fórmula:C17H19ClF3NOCor e Forma:SolidPeso molecular:345.79MAO-B-IN-4
MAO-B-IN-4 (Compound 26) is a reversible monoamine oxidase B (MAO-B) inhibitor with potent in vitro activity, characterized by an IC50 value of 9 nM.Fórmula:C23H20ClF2N3Pureza:98%Cor e Forma:SolidPeso molecular:411.87AChE-IN-40
AChE-IN-40 (Compound 5C), with an inhibitory concentration 50 (IC50) of 120 nM, is an acetylcholinesterase (AChE) inhibitor suitable for Alzheimer's diseaseFórmula:C23H27NO4Cor e Forma:SolidPeso molecular:381.46Vortioxetine D8
CAS:Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).Fórmula:C18H22N2SPureza:98%Cor e Forma:SolidPeso molecular:306.5AC3-I, myristoylated
Myristoylated AC3-I is a biologically active peptide and a myristoylated variant of the Autocamtide-3-Derived Inhibitory Peptide (AC3-I).
Fórmula:C78H137N21O20Pureza:98%Cor e Forma:SolidPeso molecular:1689.05Nardoguaianone J
CAS:Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].Fórmula:C15H22O2Cor e Forma:SolidPeso molecular:234.335-methoxy-α-Ethyltryptamine
CAS:5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects.
Fórmula:C13H18N2OPureza:98.25%Cor e Forma:SolidPeso molecular:218.29
