Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(648 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.028 produtos)
- BACE(37 produtos)
- Beta Amilóide(231 produtos)
- CaMK(73 produtos)
- COX(602 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(372 produtos)
- Gama-secretase(63 produtos)
- GluR(265 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(42 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(42 produtos)
- Receptor opioide(327 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5637 produtos de "Neurociência"
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α-Conotoxin EI
CAS:Selective antagonist of neuromuscular nicotinic receptors α1β1γδFórmula:C83H125N27O27S5Pureza:98%Cor e Forma:SolidPeso molecular:2093.37CPN-219
CAS:CPN-219 is a next-generation hexapeptidic NMUR2 agonist that selectively and dose-dependently activates NMUR2, exhibiting an EC50 value of 2.2 nM [1].Fórmula:C40H72N12O8Peso molecular:849.08Asenapine citrate
CAS:Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).Fórmula:C23H24ClNO8Cor e Forma:SolidPeso molecular:477.89Glycerophosphorylethanolamine (sodium salt)
CAS:Glycerophosphorylethanolamine, a phosphatidylethanolamine metabolite, elevates in Alzheimer's and promotes Aβ40 aggregation.Fórmula:C5H13NNaO6PCor e Forma:SolidPeso molecular:237.12TIM-098a
TIM-098a is a selective AAK1 inhibitor with an IC50 of 0.24 µM. It does not inhibit CaMKK isoforms. By inhibiting AAK1 kinase activity, TIM-098a disrupts AAK1-regulated endocytosis.
Fórmula:C18H11N3O2Peso molecular:301.08513Pseudocoptisine acetate
CAS:Pseudocoptisine acetate is a quaternary alkaloid isolated from the tubers of Corydalis turtschaninovii,with anti-inflammatory properties.Fórmula:C21H17NO6Pureza:98%Cor e Forma:SolidPeso molecular:379.36Fasciculic acid A
CAS:Fasciculic acid A is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.Fórmula:C36H60O8Cor e Forma:SolidPeso molecular:620.868AChE-IN-37
AChE-IN-37 (compound A2) is an acetylcholinesterase inhibitor with an inhibitory concentration (IC50) of 0.23 µM.Fórmula:C21H12ClNO7SCor e Forma:SolidPeso molecular:457.84AC 253
CAS:Amylin (AMY3) receptor antagonist; blocks cAMP, Ca2+, PKA, MAPK, Akt, and cFOS activity; prevents Aβ-induced neuronal death. Cyclic AC 253 variant exists.Fórmula:C122H196N40O39Pureza:98%Cor e Forma:SolidPeso molecular:2847.11Dihydrochalcone
CAS:Compound PDK0018, with CAS No. 1083-30-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0018 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C15H14OCor e Forma:SolidPeso molecular:210.27Amyloid β Peptide (42-1)(human) acetate
Amyloid β Peptide (42-1)(human) acetate is the inactive form of Amyloid β Peptide (1-42).Pureza:95.20%Cor e Forma:SoildGuluronic acid
CAS:Guluronic acid (G2013) is in hyaluronic acid; a nonsteroidal anti-inflammatory with benefits.Fórmula:C6H10O7Pureza:98%Cor e Forma:SolidPeso molecular:194.139Fentonium bromide
CAS:Fentonium bromide is a biochemical.Fórmula:C31H34BrNO4Cor e Forma:SolidPeso molecular:564.51AChE-IN-49
AChE-IN-49 (Compd (S)-7g) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 0.0003 μM.Fórmula:C31H28BrClN2O3Peso molecular:590.09718Br-PBTC
CAS:Br-PBTC modulates nAChRs; targets α2/β2,4 subtypes; potent with 0.1-0.6 μM EC50; binds α subunit c-tail.Fórmula:C14H15BrN2OSCor e Forma:SolidPeso molecular:339.251-(2-Methoxyphenyl)piperazine hydrochloride
CAS:Compound PDK0265, with CAS No. 5464-78-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0265 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C11H16N2OPeso molecular:192.25Orexin B, human
CAS:Orexin B, human agonizes Orexin receptors (OX1 Ki=420 nM, OX2 Ki=36 nM), promotes feeding in rats, and is a neuropeptide.Fórmula:C123H212N44O35SPureza:98%Cor e Forma:SolidPeso molecular:2899.34AChE-IN-60
AChE-IN-60 (compound 6k) is a potent inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 values of 27 nM and 43 nM, respectively. It also inhibits monoamine oxidase MAO-A and MAO-B, with IC50 values of 353 nM and 716 nM, respectively.Fórmula:C24H29N3O4S3Peso molecular:519.13202Orexin A (human, rat, mouse)
CAS:Orexin A, a 33 AA neuropeptide in humans, rats, mice, influences various processes, studied in pancreatic function and as an OX1R antagonist.Fórmula:C152H243N47O44S4Pureza:98%Cor e Forma:SolidPeso molecular:3561.1PD24
PD24 serves as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), with inhibitory concentrations (IC50) of 1.72 μM for humanFórmula:C24H22N2O6Cor e Forma:SolidPeso molecular:434.44K1833
K1833 is an inhibitor and reactivator of human acetylcholinesterase (hrAChE), exhibiting an inhibition concentration (IC50) of 58$.Cor e Forma:Odour SolidNaratriptan D3 Hydrochloride
CAS:Naratriptan D3 Hydrochloride is the deuterium labeled Naratriptan, is a selective agonist of 5-HT1 receptor subtype.Fórmula:C17H26ClN3O2SPureza:98%Cor e Forma:SolidPeso molecular:374.94Mirtazapine N-oxide
CAS:Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.Fórmula:C17H19N3OCor e Forma:SolidPeso molecular:281.359(-)-Coclaurine hydrochloride
CAS:(-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum.Fórmula:C17H20ClNO3Pureza:99.07%Cor e Forma:SoildPeso molecular:321.8Ref: TM-TN1519L
1mg109,00€5mg235,00€1mL*10mM (DMSO)235,00€10mg349,00€25mg532,00€50mg745,00€100mg999,00€200mg1.333,00€PSEN1-IN-1
PSEN1-IN-1 (Compound (+)-13b) functions as an inhibitor of PSEN1, displaying potent inhibition of the PSEN1-APH1A and PSEN1-APH1B complexes with respective IC50Fórmula:C20H19ClF3NO3SCor e Forma:SolidPeso molecular:445.88Metixene
CAS:Metixene is an anticholinergic drug. It was developed as a treatment against Parkinson's disease.Fórmula:C20H23NSCor e Forma:LiquidPeso molecular:309.47Perlapine
CAS:Perlapine is an effective and selective HM3DQ DREADD agonist (EC50 = 2.8 nM).Fórmula:C19H21N3Cor e Forma:SolidPeso molecular:291.39mHTT-IN-1
CAS:mHTT-IN-1 is a potent inhibitor of toxic mHTT, linked to Huntington's disease, with an EC50 of 46 nM.Fórmula:C18H19N7OSCor e Forma:SolidPeso molecular:381.45Proadrenomedullin (1-20), human
CAS:Endogenous peptide; agonist of MRGPRX2 (EC50=251 nM); noncompetitive inhibitor of nicotinic receptors; reduces catecholamine secretion; antihypertensive.Fórmula:C112H178N36O27Pureza:98%Cor e Forma:SolidPeso molecular:2460.84JNJ-67569762
CAS:JNJ-67569762 is a selective BACE1 inhibitor targeting the S3 pocket ( IC 50 = 2.7 nM).Fórmula:C22H22F4N4O5SCor e Forma:SolidPeso molecular:530.49β-Amyloid (35-25)
CAS:β-Amyloid (35-25) is the reverse sequence of β-Amyloid (25-35).Fórmula:C45H81N13O14SPeso molecular:1060.27Palonosetron N-oxide
CAS:Palonosetron N-oxide: metabolite and potential impurity of 5-HT3 antagonist palonosetron; forms under oxidative stress.Fórmula:C19H24N2O2Cor e Forma:SolidPeso molecular:312.413nAChR modulator-1
CAS:nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .Fórmula:C12H8ClN3O2Cor e Forma:SolidPeso molecular:261.664,4-Difluorobenzhydrol
CAS:Compound PDK0200, with CAS No. 365-24-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0200 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C13H10F2OCor e Forma:Off-White CrystalsPeso molecular:220.21BChE-IN-10
CAS:BChE-IN-10, a strong mixed BChE inhibitor (IC50=6.4 μM), comes from Bletilla striata for AD research.Fórmula:C23H20O5Cor e Forma:SolidPeso molecular:376.4MGS0274
CAS:MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.Fórmula:C21H32FNO7Cor e Forma:SolidPeso molecular:429.485LU-32-176B
CAS:LU32-176B is a bioactive chemical.Fórmula:C23H24F2N2O2Cor e Forma:SolidPeso molecular:398.45Feralolide
CAS:Feralolide, a dihydroisocoumarin from the methanolic extract of aloe vera resin, functions as a dual inhibitor of acetylcholinesterase (AChE) andFórmula:C18H16O7Cor e Forma:SolidPeso molecular:344.32AChE-IN-36
AChE-IN-36 (compound A4) is an acetylcholinesterase inhibitor with an IC50 of 0.04 μM, influencing ROS levels and modulating the gene expression of NRF2 [1].Fórmula:C25H21ClO5SCor e Forma:SolidPeso molecular:468.95Tabernanthalog
CAS:TBG is a 5-HT2A agonist reducing alcohol/heroin cravings and promoting neuroplasticity with antidepressant effects in rodents.Fórmula:C14H18N2OPureza:99.82% - 99.89%Cor e Forma:SoildPeso molecular:230.31Ref: TM-T60221
1mg175,00€2mg264,00€1mL*10mM (DMSO)344,00€5mg404,00€10mg592,00€25mg888,00€50mg1.243,00€100mg1.701,00€500mg3.402,00€MR33317
MR33317 is an inhibitor of acetylcholinesterase with an IC50 value of 41 nM. Additionally, it acts as an agonist for brain 5-HT4 receptors.Fórmula:C22H28ClN3O2Peso molecular:401.1873-Aminopropylphosphinic acid
CAS:3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).
Fórmula:C3H10NO2PCor e Forma:SolidPeso molecular:123.092Echimidine N-oxide
CAS:Echimidine N-oxide, a pyrrolizidine alkaloid, exhibits significant inhibitory activity against acetylcholinesterase (AChE) with an IC50 value of 0.347 mM.Fórmula:C20H31NO8Cor e Forma:SolidPeso molecular:413.47Cyclodrine
CAS:Cyclodrine (Cyclopent) is a cholinergic (muscarinic, nicotinic) (mAChR and nAChR) receptor antagonist.Fórmula:C19H29NO3Pureza:97.62%Cor e Forma:SoildPeso molecular:319.44Ref: TM-T10914L
1mg73,00€1mL*10mM (DMSO)148,00€5mg149,00€10mg212,00€25mg319,00€50mg447,00€100mg610,00€200mg822,00€4-Chloromethamphetamine hydrochloride
CAS:4-Chloromethamphetamine hydrochloride is a novel psychoactive substance belonging to the amphetamine class.Fórmula:C10H15Cl2NCor e Forma:SolidPeso molecular:220.14Antidepressant agent 5
CAS:Antidepressant agent 5 is a 7-substituted tetrahydroisoquinoline derivative with antidepressant activity.Antidepressant agent 5 acts similarly to magnoflorine
Fórmula:C20H25NO3Pureza:99.34%Cor e Forma:SoildPeso molecular:327.42AChE/BChE-IN-11
CAS:AChE/BChE-IN-11, natural from artichoke leaves, inhibits AChE and BChE (IC50: 70/71 μM) for Alzheimer's research.Fórmula:C21H22O12Cor e Forma:SolidPeso molecular:466.39SC-53116
CAS:SC-53116 HCl can increase the production of serotonin in central nervous system tissues and is a psychoactive agent.Fórmula:C16H22ClN3O2Cor e Forma:SolidPeso molecular:323.82β-Amyloid (18-28)
CAS:Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice.Fórmula:C55H81N13O18Pureza:98%Cor e Forma:SolidPeso molecular:1212.31XL01126
XL01126 degrades LRRK2 (DC50: 14 nM G2019S, 32 nM WT), crosses the blood-brain barrier, aiding Parkinson's studies.Fórmula:C50H64ClFN10O6S2Cor e Forma:SolidPeso molecular:1019.69
