Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(647 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.025 produtos)
- BACE(37 produtos)
- Beta Amilóide(230 produtos)
- CaMK(73 produtos)
- COX(602 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(373 produtos)
- Gama-secretase(62 produtos)
- GluR(265 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(43 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(41 produtos)
- Receptor opioide(327 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5639 produtos de "Neurociência"
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(R,R)-Palonosetron Hydrochloride
CAS:(R,R)-Palonosetron Hydrochloride is the active enantiomer of PalonosetronFórmula:C19H25ClN2OPureza:98%Cor e Forma:SolidPeso molecular:332.87Donitriptan hydrochloride
CAS:Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectivelyFórmula:C23H26ClN5O2Pureza:99.8% - 99.86%Cor e Forma:SolidPeso molecular:439.94Ref: TM-T21666
500mgA consultar2mg40,00€5mg49,00€10mg64,00€25mg135,00€50mg240,00€100mg339,00€200mg439,00€Rovalpituzumab MMAE
Rovalpituzumab-MMAE (Anti-DLL3 Reference Antibody), produced in CHO cells, consists of a huIgG1 heavy chain and a hukappa light chain. The molecular weight of this antibody is predicted to be 145.02 kDa.Cor e Forma:LiquidPeso molecular:145 kDaBACE1-IN-6
CAS:BACE1-IN-6 is a BACE1 inhibitor with an IC 50 value of 1.5 nM.Fórmula:C25H23F2N5O2SCor e Forma:SolidPeso molecular:495.55RBPJ Inhibitor-1
CAS:RBPJ Inhibitor-1 (RIN1), a compound that impedes the functional interaction between RBPJ and SHARP, effectively inhibits NOTCH-dependent tumor cellFórmula:C17H14FN3O2Pureza:99.79%Cor e Forma:SoildPeso molecular:311.31Ref: TM-T35566
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg130,00€25mg215,00€50mg371,00€100mg537,00€5-MeO-pyr-T
CAS:5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.Fórmula:C15H20N2OCor e Forma:SolidPeso molecular:244.33DAA-1106
CAS:DAA-1106 is a potent and selective ligand for PBR, acting as a potent and selective agonist at the peripheral benzodiazepine receptor.Fórmula:C23H22FNO4Pureza:99.54%Cor e Forma:SolidPeso molecular:395.422,6-DMA hydrochloride
CAS:2,6-DMA hydrochloride is a phenethylamine and acts as an agonist of the serotonin 5-HT2 receptor, with a pA2 value of 5.09.Fórmula:C11H18ClNO2Cor e Forma:SolidPeso molecular:231.72AChE-IN-42
Compound AChE-IN-42, also known as Compound 28, is an acetylcholinesterase (AChE) inhibitor with an inhibition constant (K i) of 0.44 μM [1].Cor e Forma:Odour SolidSoclenicant
CAS:Soclenicant is a negative-altering modulator of α 7 -nAChR for anxiety, depression, and PTSD, due to its high selectivity, oral availabilityFórmula:C24H26N4O3Pureza:99.57%Cor e Forma:SoildPeso molecular:418.49Anisatin
Anisatin is a useful organic compound for research related to life sciences and the catalog number is T124719.Fórmula:C15H20O8Cor e Forma:SolidPeso molecular:328.317β-Amyloid (10-20)
CAS:Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-Fórmula:C71H99N17O16Pureza:98%Cor e Forma:Lyophilized PowderPeso molecular:1446.652-(2-(1-Benzylpiperidin-4-yl)ethyl)isoindoline-1,3-dione
CAS:2-(2-(1-Benzylpiperidin-4-yl)ethyl)isoindoline-1,3-dione exhibits acetylcholinesterase inhibitory activity with an IC50 of 0.08 µM.Fórmula:C22H24N2O2Pureza:99.41%Peso molecular:348.44AChE/BChE-IN-13
AChE/BChE-IN-13 (compound 5j) serves as a potent dual inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting half-maximalFórmula:C21H18N8O7Cor e Forma:SolidPeso molecular:494.42Exosome Compound Library
76 exosome-related compounds that can be used for high-throughput and high-content screening.
Cor e Forma:Odour SolidSLAFVDVLN
SLAFVDVLN is a peptide molecule that functions as a BACE-1 inhibitor, exhibiting a Ki value of 94 nM. Additionally, SLAFVDVLN is capable of reducing the production of Aβ42.Fórmula:C45H72N10O14Cor e Forma:SolidPeso molecular:977.11Quetiapine-d4 fumarate
CAS:Deuterium-labeled Quetiapine fumarate; an antidepressant and anxiolytic 5-HT agonist, dopamine antagonist.Fórmula:C25H29N3O6SPureza:98%Cor e Forma:SolidPeso molecular:503.61β-Secretase Inhibitor I
CAS:β-Secretase Inhibitor I is a highly potent inhibitor of the β-secretase enzyme.Fórmula:C18H18F3N5O2SCor e Forma:SolidPeso molecular:425.43Orexin A (human, rat, mouse) acetate
Orexin A (human, rat, mouse) acetate (Hypocretin-1 (human, rat, mouse) acetate) is an excitatory neuropeptide with analgesic properties.Fórmula:C154H247N47O46S4Cor e Forma:SolidPeso molecular:3621.15PF-03382792
CAS:PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.Fórmula:C23H32FN3O4Pureza:99.64%Cor e Forma:SolidPeso molecular:433.52α-Conotoxin AuIB
CAS:Selective antagonist of α3β4 nicotinic acetylcholine receptors.Fórmula:C65H89N17O21S4Pureza:98%Cor e Forma:SolidPeso molecular:1572.765-HT2A receptor agonist-6
CAS:5-HT2A receptor agonist-6 (compound 47) is a selective agonist of the 5-HT2A receptor with a pEC50 value of 6.58.Fórmula:C18H19N3O3Cor e Forma:SolidPeso molecular:325.36Vanutide cridificar
CAS:Vanutide cridificar (ACC-001) is an aminoterminal Aβ1-7 peptide conjugate, employed in Alzheimer’s disease (AD) research [1].Cor e Forma:LiquidPotassium Channel Targeted Library
A unique collection of xnum potassium channel blockers and agonists for high throughput and high content screening;Cor e Forma:Odour SolidRef: TM-L7300
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultar3-Chloroamphetamine hydrochloride
CAS:3-Chloroamphetamine hydrochloride is a derivative of amphetamine that acts as a central nervous system stimulant by releasing serotonin and dopamine.Fórmula:C9H13Cl2NCor e Forma:SolidPeso molecular:206.11Calmodulin-Dependent Protein Kinase II (281-309)
CAS:Calmodulin-Dependent Protein Kinase II (281-309) is a synthetic peptide that can be phosphorylated at Thr286 by PKC and inhibits CaM kinase II (IC50 = 80 nM).Fórmula:C146H254N46O39S3Pureza:98%Cor e Forma:SolidPeso molecular:3374.06Fezolamine
CAS:Fezolamine: a new, non-tricyclic, oral antidepressant, selectively inhibits norepinephrine uptake over serotonin or dopamine.Fórmula:C20H23N3Pureza:99.86%Cor e Forma:SolidPeso molecular:305.42BACE1-IN-15
BACE1-IN-15 (Compound 72) is a selective β-secretase 1 (BACE-1) inhibitor with oral bioavailability and blood-brain barrier permeability, exhibiting an IC50 value of 121.65 nM, and an IC50 of 480.92 nM for BACE-2. BACE1-IN-15 is applicable for research in the field of Alzheimer's disease.Cor e Forma:Odour SolidFemoxetine
CAS:Femoxetine: antidepressant, enhances morphine, inhibits MAO-A/B, boosts mice's exercise capacity.Fórmula:C20H25NO2Pureza:99.1% - 99.35%Cor e Forma:SolidPeso molecular:311.421-Ethyl-1H-indole
CAS:1-Ethyl-1H-indole exhibits inhibitory activity against AChE (IC₅₀ = 101 µM) and can be used in related research in the field of life sciences.Fórmula:C10H11NPureza:98.80%Cor e Forma:SolidPeso molecular:145.2Histamine & Melatonin Receptor-Targeted Compound Library
A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS
Cor e Forma:Odour SolidCinazepam
CAS:Cinazepam is a GABAA receptor partial agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders.Fórmula:C19H14BrClN2O5Cor e Forma:SolidPeso molecular:465.68Neurotransmitter Receptor Compound Library
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；
Cor e Forma:Odour Solidα-Bungarotoxin
CAS:Neurotoxin that blocks neuromuscular transmission via irreversible inhibition of nicotinic ACh receptors (nAChRs).Fórmula:C338H529N97O105S11Pureza:98%Cor e Forma:SolidPeso molecular:7984.14rac-Desethyl Oxybutynin (hydrochloride)
CAS:rac-Desethyl oxybutynin, active oxybutynin metabolite, binds to mAChRs; K_i values 3.12-16 nM; lowers rat micturition pressure.Fórmula:C20H28ClNO3Cor e Forma:SolidPeso molecular:365.89(-)-2-Phenylpropylamine
CAS:(-)-2-Phenylpropylamine ((S)-2-Phenylpropylamine) (compound 3b) functions as an inhibitor for both MAO-A and MAO-B, with Ki values of 584 μM and 156 μM, respectively.Fórmula:C9H13NCor e Forma:SolidPeso molecular:135.21AChE-IN-41
AChE-IN-41 (Compound 2), a Galantamine-Memantine hybrid, possesses cholinesterase inhibitory capabilities.Cor e Forma:Odour SolidBChE-IN-19
BChE-IN-19 (Compound 7b), a para-substituted indone derivative, exhibits potent inhibitory activity against butyryl cholinesterase (BChE) with an IC50 value ofFórmula:C25H31NO5Cor e Forma:SolidPeso molecular:425.52Serotonin Receptor-Targeted Compound Library
A unique collection of xnum compounds targeting serotonin receptors for high throughput screening and high content screening;Cor e Forma:Odour SolidRef: TM-L2800
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarPSEM 308 hydrochloride
PSAM agonist targeting PSAML141F-GlyR and related ion channels in mice; ideal concentration ≤5 mg/kg; plasmids at Addgene.Cor e Forma:SolidHeliosupine N-oxide
Heliosupine N-oxide is a useful organic compound for research related to life sciences and the catalog number is T125058.Fórmula:C20H31NO8Cor e Forma:SolidPeso molecular:413.467Inaperisone
CAS:Inaperisone: a novel muscle relaxant that indirectly inhibits voiding reflex via brainstem GABAB receptors.Fórmula:C16H23NOPureza:98.83%Cor e Forma:SolidPeso molecular:245.36Notch 1
CAS:Notch1 (Notchhomolog 1, translocation-associated) encodes a protein that is a member of the NOTCH family. This type I transmembrane protein family is characterized by common structural features, including an extracellular domain made up of multiple epidermal growth factor-like (EGF) repeats and an intracellular domain composed of various types of domains.Fórmula:C62H97N15O22S3Cor e Forma:SolidPeso molecular:1500.725-HT6 inverse agonist 1
CAS:5-HT6 inverse agonist 1 (Compound 33) is an antagonist of the 5-HT6 receptor with a Ki of 23 nM and a Kb of 6.62 nM. This compound can inhibit 5-HT6R-mediated Cdk5 and mTOR signaling pathways and reduce tactile allodynia induced by spinal nerve ligation (SNL) in rat models.Fórmula:C22H22Cl2FN3O3SCor e Forma:SolidPeso molecular:498.4(+)-Cinchonaminone
CAS:(+)-Cinchonaminone shows monoamine oxidase (MAO) inhibitory activity.Fórmula:C19H24N2O2Cor e Forma:SolidPeso molecular:312.413AAK1-IN-9
AAK1-IN-9 (Compound 3) is an inhibitor of AAK1 (adaptor associated kinase 1) with an IC50 value of 10.92 nM, and it is applicable in the study of neurodegenerative diseases.Cor e Forma:Odour Solid4-Hydroxy MPT
CAS:4-Hydroxy MPT (4-OH-MPT) is a serotonin-active compound that acts as an agonist for 5-HT2A and 5-HT2B receptors, with EC50 values of 3.82 nM and 3.4 nM, respectively.Fórmula:C14H20N2OCor e Forma:SolidPeso molecular:232.32p-Xylene bis(pyridinium bromide)
CAS:p-Xylene bis(pyridinium bromide) (compound 21) is a cationic quenching agent and acts as a weak bis-quaternary ammonium salt inhibitor for AChE and BChE, with IC50 values of 1540 μM and 529 μM, respectively.Fórmula:C18H18Br2N2Cor e Forma:SolidPeso molecular:422.16TET-13
TET-13 is a positive allosteric modulator of the GABAA receptor with an EC50 of 5.65 μM, which is more potent than Etomidate (EC50: 9.29 μM). It exhibits strong anesthetic effects in both mice and rats, with an ED50 of 0.48 mg/kg in mice and 0.69 mg/kg in rats.Fórmula:C15H16N2O3SCor e Forma:SolidPeso molecular:304.36GABAA receptor modulator-3
GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.Fórmula:C18H22O2Cor e Forma:SolidPeso molecular:270.37
