Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(647 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.027 produtos)
- BACE(37 produtos)
- Beta Amilóide(230 produtos)
- CaMK(73 produtos)
- COX(602 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(373 produtos)
- Gama-secretase(62 produtos)
- GluR(265 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(43 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(41 produtos)
- Receptor opioide(327 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5639 produtos de "Neurociência"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Lu AE51090
CAS:Lu AE51090 is a selective muscarinic M1 receptor agonist with minimal off-target effects, receptor function and selective pharmacological modulation.Fórmula:C24H29N3O3Pureza:99.57%Cor e Forma:SolidPeso molecular:407.51TC-2559 difumarate
CAS:TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.Fórmula:C20H26N2O9Cor e Forma:SolidPeso molecular:438.43VU0483605
CAS:VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.
Fórmula:C20H10Cl3N3O3Pureza:99.61%Cor e Forma:SolidPeso molecular:446.675-MeO-pyr-T
CAS:5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.Fórmula:C15H20N2OCor e Forma:SolidPeso molecular:244.33TIP 39, Tuberoinfundibular Neuropeptide
CAS:TIP39 is a synthetic neuropeptide agonist for human and rat PTH2 receptors from the hypothalamus.Fórmula:C202H325N61O54SPureza:98%Cor e Forma:SolidPeso molecular:4504.2Calmodulin Binding Peptide 1
CAS:Calmodulin Binding Peptide 1, a high-affinity MLCK-derived inhibitor, blocks IP3-induced Ca2+ release.Fórmula:C231H373N69O70S2Pureza:98%Cor e Forma:SolidPeso molecular:5301.1JH-XII-03-02
CAS:JH-XII-03-02 is a potent and selective leucine-rich repeat kinase 2 (LRRK2) proteolysis targeting chimera (PROTAC) degrader, utilized in Parkinson's Disease (PDFórmula:C43H51N9O10Pureza:98%Cor e Forma:SolidPeso molecular:853.92(-)-Coclaurine hydrochloride
CAS:(-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum.Fórmula:C17H20ClNO3Pureza:99.07%Cor e Forma:SoildPeso molecular:321.8Ref: TM-TN1519L
1mg109,00€5mg235,00€1mL*10mM (DMSO)235,00€10mg349,00€25mg532,00€50mg745,00€100mg999,00€200mg1.333,00€Tampramine
CAS:Tampramine: a TCA and selective norepinephrine inhibitor, with low affinity for other receptors, potential treatment for FST depression.
Fórmula:C23H24N4Pureza:99.87%Cor e Forma:SolidPeso molecular:356.46Alosetron-d3
CAS:Alosetron D3 (GR 68755 D3) is a deuterium-labeled Alosetron. Alosetron is an antagonist of 5HT3-receptor.Fórmula:C17H18N4OPureza:98%Cor e Forma:SolidPeso molecular:297.37β-Secretase Inhibitor II
CAS:β-Secretase Inhibitor II is a tripeptide aldehyde compound that acts as an inhibitor of β-Secretase.Fórmula:C25H39N3O5Cor e Forma:SolidPeso molecular:461.59Isobutyryl-L-carnitine
CAS:Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.Fórmula:C11H21NO4Pureza:98%Cor e Forma:SolidPeso molecular:231.29R-(+)-Cotinine
CAS:R-(+)-Cotinine, an inactive nicotine metabolite, boosts Ach-induced current in human α7 nAChRs.Fórmula:C10H12N2OCor e Forma:SolidPeso molecular:176.22(Iso)-Landipirdine
CAS:(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.Fórmula:C18H19FN2O3SPureza:98.94%Cor e Forma:SoildPeso molecular:362.42Epiboxidine hydrochloride
CAS:Epiboxidine HCl: potent α4β2 nAChR agonist; Ki 0.46 nM (rat), 1.2 nM (human); Epibatidine analog.Fórmula:C10H15ClN2OCor e Forma:SolidPeso molecular:214.69Epiboxidine
CAS:Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.Fórmula:C10H14N2OCor e Forma:SolidPeso molecular:178.23CHF-5022
CAS:CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).Fórmula:C17H12F4O2Cor e Forma:SolidPeso molecular:324.27CGP 35348
CAS:CGP 35348 是 GABAB 受体的选择性拮抗剂 (EC50 = 34 μM)。 CGP 35348 可用于研究白化新生小鼠脑损伤后的神经肌肉协调和空间学习。Fórmula:C8H20NO4PPureza:≥98%Cor e Forma:SolidPeso molecular:225.22Perlapine
CAS:Perlapine is an effective and selective HM3DQ DREADD agonist (EC50 = 2.8 nM).Fórmula:C19H21N3Cor e Forma:SolidPeso molecular:291.39BChE-IN-40
BChE-IN-40 (compound D40) is a potent butyrylcholinesterase inhibitor with an IC50 of 0.59 μM. It demonstrates significant anti-inflammatory effects, with an IC50 of 4.55 μM in inhibiting nitric oxide production. Additionally, BChE-IN-40 exhibits excellent permeability across the blood-brain barrier.Fórmula:C28H30N2O7Cor e Forma:SolidPeso molecular:506.2053nAChR agonist CMPI hydrochloride
CAS:CMPI hydrochloride: Potent α4:α4 nAChR PAM; EC50 0.26 μM for (α4)3(β2)2 response to ACh; may aid nicotine dependence, neuropsychiatric research.Fórmula:C18H20Cl2N4OCor e Forma:SolidPeso molecular:379.29γ-Secretase modulator 10
CAS:γ-Secretase modulator 10 is a novel γ-secretase modulator.Fórmula:C25H23F3N4O2Cor e Forma:SolidPeso molecular:468.484-P-PDOT
CAS:4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.Fórmula:C19H21NOPureza:99.91%Cor e Forma:SolidPeso molecular:279.38ACHE Inhibitor 12
CAS:ACHE Inhibitor 12 inhibited acetylcholinesterase with an IC50 value of 0.38 µM.Fórmula:C11H12OPureza:97.07%Cor e Forma:SolidPeso molecular:160.21Org 24598 lithium salt
CAS:Org 24598 lithium salt is a GlyT-1 inhibitor of glycine transporter 1.Fórmula:C19H19F3LiNO3Cor e Forma:SolidPeso molecular:373.3Doxacurium Chloride
CAS:Doxacurium Chloride is a muscarinic acetylcholine receptor M2 antagonist.Fórmula:C56H78ClN2O16Pureza:98%Cor e Forma:SolidPeso molecular:1070.69Atracurium
CAS:Atracurium (BW-33A) is a competitive AChR antagonist and non-depolarizing muscle relaxant that may cause bronchoconstriction.Fórmula:C53H72N2O122Cor e Forma:SolidPeso molecular:929.14AChE-IN-45
AChE-IN-45 (Compound 14) is an acetylcholinesterase (AChE) inhibitor exhibiting an IC50 value of 11.57±0.45 nM, and it demonstrates both antioxidant andCor e Forma:Odour SolidRN277
RN277 is an inhibitor of LRRK2 type II kinase (LRRK2type II kinase). It serves as a cellular tool targeting the inactive state of LRRK2. In vitro, RN277 inhibits LRRK1 kinase activity and the kinase activity of LRRK2, with an IC50 of 70 nM. Additionally, it reduces Rab8a phosphorylation in a dose-dependent manner. RN277 is useful for Parkinson's disease research.Cor e Forma:Odour Solidβ-Amyloid (1-17)
CAS:This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.Fórmula:C90H130N28O29Pureza:98%Cor e Forma:SolidPeso molecular:2068.2Multitarget AD inhibitor-1
CAS:Multitarget AD inhibitor-1: reversible, selective BuChE blocker, inhibits β-secretase and amyloid/tau aggregation, promising for Alzheimer's research.Fórmula:C29H38N2OCor e Forma:SolidPeso molecular:430.636β-Amyloid (12-20)
CAS:β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad hasFórmula:C57H83N15O11Pureza:98%Cor e Forma:SolidPeso molecular:1154.36Flupyradifurone
CAS:Flupyradifurone (flupyradifurone) is a systemic insecticide and nicotinic acetylcholine receptor (nAChR) agonist interfer nervous system of insects.Fórmula:C12H11ClF2N2O2Pureza:99.83%Cor e Forma:SolidPeso molecular:288.68AChE/BChE-IN-14
AChE/BChE-IN-14 (compound 13), a benzylisoquinoline alkaloid extracted from Fissistigma polyanthum roots, demonstrates inhibitory effects on bothFórmula:C19H23NO3Cor e Forma:SolidPeso molecular:313.39Cevimeline hydrochloride hemihydrate
CAS:Cevimeline hydrochloride hemihydrate is a novel muscarinic receptor agonist, used as a candidate therapeutic drug for xerostomia in Sjogren's syndrome.
Fórmula:C20H38Cl2N2O3S2Pureza:97.00%Cor e Forma:SolidPeso molecular:489.55nAChR modulator-1
CAS:nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .Fórmula:C12H8ClN3O2Cor e Forma:SolidPeso molecular:261.66Chrysophanol-1-O-β-gentiobioside
CAS:Chrysophanol-1-O-β-gentiobioside, an anthraquinone glycoside obtained from the seeds of Cassia obtusifolia, exhibits targeted inhibition of hMAO-A isozymeFórmula:C27H30O14Cor e Forma:SolidPeso molecular:578.52Lupanine perchlorate
CAS:Lupanine perchlorate is a bioactive chemical.Fórmula:C15H25ClN2O5Cor e Forma:SolidPeso molecular:348.82Amyloid-β-IN-1
Amyloid-β-IN-1 (compound 13), a synthetic peptide featuring the hydrophobic C-terminal segment "VVIA-NH2" and its reversed sequence "AIVV-NH2" derived from Aβ 42, acts as an Aβ inhibitor. It effectively inhibits Aβ aggregation and exhibits neuroprotective effects.Fórmula:C18H35N5O4Peso molecular:385.5(±)-Coniine
CAS:(±)-Coniine, a piperidine alkaloid, is a toxin found in poison hemlock.Fórmula:C8H17NCor e Forma:SolidPeso molecular:127.23CALP2
CAS:CALP2 is a CaM antagonist blocking EF-hand/Ca2+ site; inhibits CaM phosphodiesterase, raises Ca2+, and activates alveolar macrophages.Fórmula:C68H104N14O13SPureza:98%Cor e Forma:SolidPeso molecular:1357.72VVZ-149
VVZ-149 is an antagonist of both serotonin receptor 2A (5HT2A) and glycine transporter type 2 (GlyT2), with potential anti-nociceptive activity.Cor e Forma:SolidMRS8209
MRS8209 is an antagonist of the serotonin receptor (serotonin receptor), with a Ki value of 4.27 nM specifically for 5-HT2BR. It provides protective effects on pulmonary airway opening pressure (PAO) and is applicable in pulmonary fibrosis studies.Fórmula:C17H19IN6O2Cor e Forma:SolidPeso molecular:466.276BChE-IN-10
CAS:BChE-IN-10, a strong mixed BChE inhibitor (IC50=6.4 μM), comes from Bletilla striata for AD research.Fórmula:C23H20O5Cor e Forma:SolidPeso molecular:376.4MGS0274
CAS:MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.Fórmula:C21H32FNO7Cor e Forma:SolidPeso molecular:429.485Echimidine N-oxide
CAS:Echimidine N-oxide, a pyrrolizidine alkaloid, exhibits significant inhibitory activity against acetylcholinesterase (AChE) with an IC50 value of 0.347 mM.Fórmula:C20H31NO8Cor e Forma:SolidPeso molecular:413.47Riluzole-13C,15N2
CAS:Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.Fórmula:CC7H5F3OS15N2Cor e Forma:SolidPeso molecular:237.18Crenezumab
CAS:Crenezumab (MABT 5102A) is a fully humanized anti-amyloid-beta antibody that binds to multiple forms of amyloid-beta (Aβ) for the study of Alzheimer's disease.Pureza:97.5% (SDS-PAGE); 95.3% (SEC-HPLC) - 97.5% (SDS-PAGE); 95.3% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:143.32 kDaAntidepressant agent 10
CAS:Compound PDK0386, with CAS No. 87691-87-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0386 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C11H13N3SPeso molecular:219.306Methylatropine (nitrate)
CAS:Methylatropine: Muscarinic antagonist, <0.1 nM IC50, atropine derivative, lowers ACh's effect on BP, affects salivation, pupil dilation, heart rate.Fórmula:C18H26N2O6Cor e Forma:SolidPeso molecular:366.414
