Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(642 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(2.998 produtos)
- BACE(37 produtos)
- Beta Amilóide(217 produtos)
- CaMK(73 produtos)
- COX(598 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(370 produtos)
- Gama-secretase(57 produtos)
- GluR(265 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(43 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(325 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5446 produtos de "Neurociência"
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SKF89976A HCl
CAS:SKF89976A: GABA uptake inhibitor, selective for GAT-1, passes blood-brain barrier, active in vivo (IC50: 0.13 μM hGAT-1).Fórmula:C22H25NO2Cor e Forma:SolidPeso molecular:335.44Hemicholinium 3
CAS:Hemicholinium 3 is a potent and selective choline uptake blocker.Fórmula:C24H34Br2N2O4Pureza:98% - 99.95%Cor e Forma:SolidPeso molecular:574.35MDL 100009
CAS:MDL 100009, the S-enantiomer of MDL 100151 and the opposite enantiomer of MDL 100907, is a selective antagonist of 5-HT2A.Fórmula:C22H28FNO3Pureza:98.96%Cor e Forma:SolidPeso molecular:373.46Ref: TM-T22359
1mg99,00€5mg187,00€10mg280,00€25mg434,00€50mg585,00€100mg775,00€200mg1.054,00€1mL*10mM (DMSO)222,00€Escitalopram Oxalate
CAS:Escitalopram Oxalate ((S)-(+)Citalopram oxalate) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.Fórmula:C22H23FN2O5Pureza:97.39% - 99.73%Cor e Forma:White SolidPeso molecular:414.43Ref: TM-T6493
1g268,00€10mg37,00€25mg52,00€50mg63,00€100mg86,00€200mg118,00€500mg187,00€1mL*10mM (DMSO)42,00€Sumatriptan hydrochloride
CAS:Sumatriptan hydrochloride (GR 43175), an oral 5-HT1 receptor agonist, treats migraines; Ki: 5-HT1D - 17 nM, 5-HT1B - 27 nM, 5-HT1A - 100 nM.Fórmula:C14H22ClN3O2SCor e Forma:SolidPeso molecular:331.86Guvacine hydrochloride
CAS:Guvacine hydrochloride is an inhibits of GABA uptake (IC50 : 10 μM)Fórmula:C6H10ClNO2Pureza:98.42%Cor e Forma:SolidPeso molecular:163.602Gabazine
CAS:Gabazine (SR95531) is an antagonist of GABAA receptors (Ki : 74-150 nM)Fórmula:C15H18BrN3O3Pureza:98.51% - 99.24%Cor e Forma:SolidPeso molecular:368.23Revefenacin
CAS:Revefenacin (TD-4208) is a mAChR antagonist has a high affinity on M3 receptor( Ki : 0.18 nM),and potentially useful for the treatment of respiratory disease.Fórmula:C35H43N5O4Pureza:98.12%Cor e Forma:SolidPeso molecular:597.751-[10-(pyridin-1-ium-1-yl)decyl]pyridin-1-ium dibromide
CAS:1-[10-(pyridin-1-ium-1-yl)decyl]pyridin-1-ium dibromide is the inhibitor of human erythrocyte AChE.
Fórmula:C20H30Br2N2Pureza:98.17%Cor e Forma:SolidPeso molecular:458.27Mosapride Citrate
CAS:Mosapride Citrate (TAK-370 citrate), a gastroprokinetic agent, utilizes as a selective 5HT4 agonist.Fórmula:C21H25ClFN3O3·C6H8O7Pureza:99.70%Cor e Forma:White PowderPeso molecular:614.02Acotiamide monohydrochloride trihydrate
CAS:Acotiamide monohydrochloride trihydrate (Z-338 HCl) is the hydrochloride salt form of acotiamide, a prokinetic agent with GI motility-enhancing activity.Fórmula:C21H37ClN4O8SPureza:98% - 99.54%Cor e Forma:SolidPeso molecular:541.06PNU-282987 S enantiomer free base
CAS:PNU-282987 S enantiomer free base is an agonist of α7 nicotinic acetylcholine receptor (α7 nAChR).Fórmula:C14H17ClN2OPureza:99.74%Cor e Forma:SolidPeso molecular:264.75Ref: TM-T7695
1mg71,00€5mg161,00€10mg219,00€25mg338,00€50mg460,00€100mg623,00€200mg837,00€1mL*10mM (DMSO)180,00€Org 25543 hydrochloride
CAS:Org 25543 hydrochloride is a potent and selective glycine transporter type 2 (GlyT2) inhibitor (IC50 = 16 nM for hGlyT2).Fórmula:C24H33ClN2O4Pureza:99.26%Cor e Forma:SolidPeso molecular:448.983Prucalopride Succinate
CAS:Prucalopride Succinate is a 5-HT4 receptor agonist with Ki 2.5 nM (5-HT4a) and 8 nM (5-HT4b).Fórmula:C18H26ClN3O3·C4H6O4Pureza:99.24%Cor e Forma:SolidPeso molecular:485.96JNJ-40411813
CAS:JNJ-40411813 (ADX-71149) (ADX-71149) is a new positive allosteric modulator of the metabotropic glutamate 2 receptor (mGlu2R, EC50: 147 nM).
Fórmula:C20H25ClN2OPureza:99.74%Cor e Forma:SolidPeso molecular:344.88Intepirdine
CAS:Intepirdine (GSK-742457) is a highly selective 5-HT6 receptor antagonist, used in trials studying the treatment of Alzheimer's Disease.Fórmula:C19H19N3O2SPureza:98% - 98.63%Cor e Forma:SolidPeso molecular:353.44GR 125743
CAS:GR 125743 is a novel antagonist of 5-HT1B/1D receptor.Fórmula:C25H28N4O2Pureza:99.76%Cor e Forma:SolidPeso molecular:416.52Ref: TM-T8737
1mg40,00€2mg52,00€5mg84,00€10mg113,00€25mg222,00€50mg333,00€100mg495,00€1mL*10mM (DMSO)93,00€N-ACETYLTRYPTAMINE
CAS:N-ACETYLTRYPTAMINE is a partial agonist for melatonin receptors in the retina. Also used for determination of serotonin N-acetyl transferase.Fórmula:C12H14N2OPureza:98.79%Cor e Forma:PowderPeso molecular:202.25Flibanserin
CAS:Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder.
Fórmula:C20H21F3N4OPureza:99.37% - 99.93%Cor e Forma:White PowderPeso molecular:390.4MPEP hydrochloride
CAS:MPEP hydrochloride is an effective and highly specific non-competitive antagonist at the mGlu5 receptor subtype (IC50: 36 nM).
Fórmula:C14H12ClNPureza:99.87% - >99.99%Cor e Forma:SolidPeso molecular:229.7LY2886721
CAS:LY2886721, a BACE inhibitor, is used for the therapy of Alzheimer's Disease.Fórmula:C18H16F2N4O2SPureza:99% - 99.75%Cor e Forma:SolidPeso molecular:390.41SB-200646
CAS:SB-200646 is a selective and potent antagonist of 5-HT2B/5-HT2C receptorFórmula:C15H14N4OPureza:99.61%Cor e Forma:SolidPeso molecular:266.3PNU 22394 hydrochloride
CAS:PNU 22394 hydrochloride is a 5-HT2C agonist and partial 5-HT2A/5-HT2B agonistFórmula:C13H17ClN2Pureza:97.83%Cor e Forma:SolidPeso molecular:236.74Jagged-1 (188-204) TFA(219127-21-6 free base)
Jagged-1 (188-204) TFA, a JAG-1 skin protein fragment, induces epidermal maturation and keratinocyte stratification.Fórmula:C95H128F3N25O28S3Pureza:99.48%Cor e Forma:SolidPeso molecular:2221.37GALANTHAMINONE
CAS:Galanthaminone ((-)-Narwedine) is a cholinesterase (AChE) inhibitor, used for the treatment of mild to moderate Alzheimer's disease and other memory impairments
Fórmula:C17H19NO3Pureza:99.93%Cor e Forma:White To Off-White ChemicalPeso molecular:285.34W-84 dibromide
CAS:W-84 dibromide (HDMPPA) is a M2-receptor selective modulator.Fórmula:C32H44Br2N4O4Pureza:95.56%Cor e Forma:SolidPeso molecular:708.52Opiranserin hydrochloride
CAS:Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μMFórmula:C21H35ClN2O5Pureza:99.33%Cor e Forma:SolidPeso molecular:430.97Ref: TM-T9833
1mg90,00€5mg215,00€10mg340,00€25mg618,00€50mg879,00€100mg1.224,00€500mg2.457,00€1mL*10mM (DMSO)236,00€AC-90179 HCl
CAS:AC-90179 HCl: selective 5-HT2A inverse agonist, atypical antipsychotic, reduces hallucinogen-induced vasoconstriction.Fórmula:C23H31ClN2O2Pureza:99.71%Cor e Forma:SolidPeso molecular:402.96AVN-492
CAS:AVN-49 is a potent and selective 5-HT6R Antagonist (Ki: 91 pM).Fórmula:C17H21N5O2SPureza:99.81%Cor e Forma:SolidPeso molecular:359.45Ref: TM-T5179
1mg37,00€2mg50,00€5mg77,00€10mg114,00€25mg225,00€50mg335,00€100mg484,00€1mL*10mM (DMSO)85,00€CFMTI
CAS:CFMTI: potent mGluR1 allosteric antagonist, 2000x selectivity over mGluR5, IC50: 2.6 nM.Fórmula:C19H16FN5OPureza:97.23%Cor e Forma:SolidPeso molecular:349.36Ref: TM-T3482
1mg57,00€2mg82,00€5mg120,00€10mg170,00€25mg304,00€50mg432,00€100mg602,00€1mL*10mM (DMSO)133,00€γ-Mangostin
CAS:Gamma-Mangostin (Normangostin) has free radical scavenging activity, and antiproliferative and apoptotic activity. Gamma-Mangostin is an antihypertensive agent.Fórmula:C23H24O6Pureza:98.55% - 99.08%Cor e Forma:SolidPeso molecular:396.434-Acetamidobutanoic acid
CAS:4-Acetamidobutanoic acid, a GABA derivative in eukaryotes, found in blood, feces, urine, and human prostate.Fórmula:C6H11NO3Pureza:98.51%Cor e Forma:SolidPeso molecular:145.16VUF 10166
CAS:VUF10166 is a novel, potent and competitive antagonist for 5-HT3A receptor with Ki of 0.04 nM, its affinity at 5-HT3AB receptor is significantly lower.Fórmula:C13H15ClN4Pureza:99.66%Cor e Forma:SolidPeso molecular:262.74NS9283
CAS:NS9283, a positive allosteric modulator selective for the α4β2 form, reduces ethanol consumption.
Fórmula:C14H8N4OPureza:99.12%Cor e Forma:SolidPeso molecular:248.24SR 57227 hydrochloride
CAS:SR 57227A (SR 57227 hydrochloride) is a potent, orally active and selective 5-HT3 receptor agonist. It with ability to cross the blood brain barrier.Fórmula:C10H14ClN3·HClPureza:99.89%Cor e Forma:SolidPeso molecular:248.15Amyloid β-Protein 10-20 acetate
Amyloid β-Protein 10-20 acetate (Amyloid β-Protein 10-20 acetate (152286-31-2 free base)) is a fragment of Amyloid-β peptide, maybe used in the research ofFórmula:C73H103N17O18Pureza:97.23%Cor e Forma:SolidPeso molecular:1506.65Lu AF21934
CAS:Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human).
Fórmula:C14H16Cl2N2O2Pureza:99.79%Cor e Forma:SolidPeso molecular:315.2Nemifitide acetate(173240-15-8 free base)
Nemifitide acetate, synthetic 5-amino acid antidepressant, has quick effect, mimics MIF.Fórmula:C35H47FN10O8Pureza:97.97%Cor e Forma:SolidPeso molecular:754.855-Benzyloxygramine
CAS:5-Benzyloxygramine blocks the Dopamin receptors and antagonizes the effects of 5-HT on the rat uterus and the rabbit ear.Fórmula:C18H20N2OPureza:99.13%Cor e Forma:SolidPeso molecular:280.36SSR504734
CAS:SSR504734 is a novel potent glycine transporter 1 (GlyT1) inhibitor.Fórmula:C20H20ClF3N2OCor e Forma:SolidPeso molecular:396.83CGP52432
CAS:CGP52432 is a very potent antagonist of GABAB receptors (IC50 = 85 nM).Fórmula:C15H24Cl2NO4PPureza:98.75%Cor e Forma:SolidPeso molecular:384.24Dasotraline hydrochloride
CAS:Dasotraline hydrochloride, a dopamine, norepinephrine, and serotonin reuptake inhibitor with IC50s: 4, 6, 11 nM.Fórmula:C16H16Cl3NPureza:98.92% - 99.6%Cor e Forma:SolidPeso molecular:328.66Clozapine N-Oxide
CAS:View and buy CLOZAPINE N-OXIDE from TargetMol.Clozapine N-oxide is a major metabolite of clozapine also known as DREADDs, technology to modulate synthetic receptors in vivo.Cited in 2 publications.Fórmula:C18H19ClN4OPureza:98.65% - 99.94%Cor e Forma:SolidPeso molecular:342.82Pergolide mesylate
CAS:Pergolide mesylate (LY127809), a dopamine agonist for Parkinson's and hyperprolactinemia, was withdrawn for heart valve risk.Fórmula:C20H30N2O3S2Pureza:99.70%Cor e Forma:White To Off-White SolidPeso molecular:410.596-fluoro-DL-Tryptophan
CAS:6-fluoro-DL-Tryptophan is an inhibitor of serotonin (5-HT) synthesis.Fórmula:C11H11FN2O2Pureza:99.25%Cor e Forma:Off-White PowderPeso molecular:222.22β-Amyloid 15-21 acetate
β-Amyloid 15-21 acetate (Beta-Amyloid (15-21) acetate) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Fórmula:C45H69N9O11Pureza:99.62%Cor e Forma:SolidPeso molecular:912.1N-Desmethylclozapine
CAS:N-Desmethylclozapine: 5-HT2C antagonist (IC50: 7.1 nM), dopamine D4 antagonist, δ-opioid agonist.Fórmula:C17H17ClN4Pureza:97.25% - 99.83%Cor e Forma:Yellow Crystalline SolidPeso molecular:312.8Ref: TM-T5158
2mg34,00€5mg48,00€10mg79,00€25mg152,00€50mg235,00€100mg344,00€200mg490,00€1mL*10mM (DMSO)58,00€TBPB
CAS:TBPB is an allosteric M1 mAChR agonist.
Fórmula:C25H32N4OPureza:97.87% - 99.9%Cor e Forma:SolidPeso molecular:404.55L-745870 trihydrochloride
CAS:L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist.
Fórmula:C18H22Cl4N4Pureza:97.52%Cor e Forma:SolidPeso molecular:436.21pyridostigmine
CAS:Pyridostigmine(Regonol) is an acetylcholinesterase inhibitor that can treat myasthenia gravis by increasing acetylcholine at the postsynaptic motor endplate.Fórmula:C9H13N2O2Pureza:98.10%Cor e Forma:SolidPeso molecular:181.21Ref: TM-T8631
1mg88,00€5mg170,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)167,00€
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