Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(639 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(2.994 produtos)
- BACE(37 produtos)
- Beta Amilóide(221 produtos)
- CaMK(73 produtos)
- COX(600 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(369 produtos)
- Gama-secretase(57 produtos)
- GluR(265 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(43 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(41 produtos)
- Receptor opioide(325 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5467 produtos de "Neurociência"
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Zacopride hydrochloride
CAS:Zacopride is a highly potent 5-HT3 receptor antagonist (Kd = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). It also is a selective IK1 channel agonist.Fórmula:C15H20ClN3O2·HClPureza:98.32%Cor e Forma:SolidPeso molecular:346.26Ref: TM-T5336
1mg34,00€5mg71,00€10mg99,00€25mg212,00€50mg385,00€100mg618,00€200mg859,00€1mL*10mM (DMSO)79,00€Quipazine maleate
CAS:Quipazine maleate is a 5-HT agonist affecting L-02 hepatocytes and raphe neurons, causing smooth muscle contracture and bronchospasm.Fórmula:C17H19N3O4Cor e Forma:SolidPeso molecular:329.356Semagacestat
CAS:Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM).Fórmula:C19H27N3O4Pureza:97.1% - 99.9%Cor e Forma:SolidPeso molecular:361.44(E)-3,4,5-Trimethoxycinnamic acid
CAS:(E)-3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) is a natural product from the roots and rhizomes of Notopterygium incisum.Fórmula:C12H14O5Pureza:99.83%Cor e Forma:SolidPeso molecular:238.24CNQX disodium
CAS:CNQX disodium is a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures.Fórmula:C9H2N4Na2O4Pureza:97.77%Cor e Forma:SolidPeso molecular:276.12Ref: TM-T8458
5mg47,00€10mg60,00€25mg119,00€50mg187,00€100mg298,00€200mg439,00€500mg715,00€1mL*10mM (DMSO)50,00€Ansofaxine
CAS:Ansofaxine, an SNRI compound, is commonly utilized in depression research as a serotonin-norepinephrine reuptake inhibitor.Fórmula:C24H31NO3Cor e Forma:SolidPeso molecular:381.516Niaprazine
CAS:Niaprazine is a histamine H1-receptor antagonist with marked sedative properties.Fórmula:C20H25FN4OPureza:99.56%Cor e Forma:SolidPeso molecular:356.44Isopropamide Iodide
CAS:Isopropamide iodide: long-acting anticholinergic, treats peptic ulcers, GI disorders, Alzheimer's.
Fórmula:C23H33IN2OPureza:99.67%Cor e Forma:SolidPeso molecular:480.43Naratriptan hydrochloride
CAS:Naratriptan Hydrochloride, a selective 5-HT1 receptor agonist with anti-migraine effect, induces vasoconstriction and reduces inflammation in migraines.Fórmula:C17H25N3O2S·HClPureza:99.17% - 99.93%Cor e Forma:Beige SolidPeso molecular:371.93Ref: TM-T6602
10mg50,00€25mg88,00€50mg133,00€100mg188,00€200mg283,00€500mg467,00€1mL*10mM (DMSO)52,00€Tiagabine hydrochloride hydrate
CAS:Tiagabine HCl hydrate, IC50: 67-446 nM, selectively inhibits GABA uptake, acts as an anticonvulsant.Fórmula:C20H28ClNO3S2Cor e Forma:SolidPeso molecular:430.02Rivanicline hemioxalate
Rivanicline hemioxalate is a selective α4β2 nicotinic receptor agonist (K i =26 nM), over 1,000x preference to α7 (K i =3.6 μM), with limited side effects.Fórmula:C12H16N2O4Pureza:98%Cor e Forma:SolidPeso molecular:207.23JI130
CAS:JI130 hinders Hes1 transcription repression; notably shrinks pancreatic tumor volume in mice.Fórmula:C23H24N2O3Pureza:99.61%Cor e Forma:SolidPeso molecular:376.45(S)-UFR2709
CAS:(S)-UFR2709, a nAChR competitive antagonist, favors α4β2 over α7, reduces anxiety and alcohol use in rats.Fórmula:C13H17NO2Cor e Forma:SolidPeso molecular:219.284Gefapixant
CAS:Gefapixant (AF219) is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptorsFórmula:C14H19N5O4SPureza:99.28% - 99.50%Cor e Forma:SolidPeso molecular:353.4CRANAD 2
CAS:CRANAD-2, a near-infrared probe, detects amyloid-beta in vivo, increasing fluorescence 70x and shifting blue 90 nm upon binding.Fórmula:C23H25BF2N2O2Pureza:99.44%Cor e Forma:Dark Blue To Black PowderPeso molecular:410.27Piboserod hydrochloride
CAS:Piboserod HCl is a selective antagonist of 5-HT4 and muscarinic receptor.Fórmula:C22H32ClN3O2Cor e Forma:SolidPeso molecular:405.96Pipequaline hydrochloride
CAS:Pipequaline hydrochloride (PK-8165 hydrochloride) is an anticonflict & anticonvulsant quinoline derivative.Fórmula:C22H25ClN2Pureza:99.46%Cor e Forma:SolidPeso molecular:352.9Cyclopiazonic acid
CAS:Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite (SM) made by A.Fórmula:C20H20N2O3Pureza:99.27% - 99.80%Cor e Forma:SolidPeso molecular:336.38Bestim
CAS:Bestim is an immunomodulatory dipeptide that is synthetic.Fórmula:C16H19N3O5Pureza:99.76%Cor e Forma:SolidPeso molecular:333.34Ref: TM-T25146
1mg88,00€5mg172,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)182,00€LY 2886721 Hydrochloride
CAS:Potent, selective BACE inhibitor; IC50 of 10.2 nM (BACE2) & 20.3 nM (BACE1). >5000x selectivity vs. other proteases. Lowers Aβ & sAPPβ in Alzheimer's mice.Fórmula:C18H17ClF2N4O2SCor e Forma:SolidPeso molecular:426.87Isocorynoxeine
CAS:Isocorynoxeine reduces blood pressure, dilates vessels, and guards neurons against ischemia and glutamate toxicity.Fórmula:C22H26N2O4Pureza:98% - 99.9%Cor e Forma:SolidPeso molecular:382.45Ref: TM-T6S0654
1mg62,00€2mg89,00€5mg132,00€10mg226,00€25mg384,00€50mg557,00€100mg785,00€200mg1.054,00€1mL*10mM (DMSO)146,00€Propantheline
CAS:Propantheline: oral muscarinic receptor blocker for smooth muscle issues, hyperhidrosis, and bladder control.Fórmula:C23H30NO3Cor e Forma:SolidPeso molecular:368.49Eltoprazine
CAS:Eltoprazine(DU28853) is a serenic or antiaggressive agent which as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor.Fórmula:C12H16N2O2Cor e Forma:SolidPeso molecular:220.27Mosapride Citrate
CAS:Mosapride Citrate (TAK-370 citrate), a gastroprokinetic agent, utilizes as a selective 5HT4 agonist.Fórmula:C21H25ClFN3O3·C6H8O7Pureza:99.70%Cor e Forma:White PowderPeso molecular:614.02Ritanserin
CAS:Ritanserin (R 55667) is a long-acting, highly potent, relatively selective, orally bioavailable 5-HT2 receptor antagonist.Cost-effective and quality-assured.Fórmula:C27H25F2N3OSPureza:99.77% - 99.89%Cor e Forma:SolidPeso molecular:477.57LP-922761 hydrate
LP-922761 hydrate: selective AAK1 inhibitor; IC50: 4.8 nM (enzyme), 7.6 nM (cellular); also inhibits BIKE (IC50: 24 nM); inert to GAK, opioids, α2, GABAa.Fórmula:C21H28N6O4Cor e Forma:SolidPeso molecular:414.98Flibanserin
CAS:Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder.
Fórmula:C20H21F3N4OPureza:99.37% - 99.93%Cor e Forma:White PowderPeso molecular:390.4ARC-239
CAS:ARC-239 is an agonist of α2-adrenergic receptor.Fórmula:C24H29N3O3Cor e Forma:SolidPeso molecular:407.51SAX-187 hydrochloride
CAS:WAY-181187 is a potent, selective 5-HT6 agonist with high affinity (2.2-4.8 nM), and increases GABA in rat cortex at 3-30 mg/kg s.c.Fórmula:C15H14Cl2N4O2S2Cor e Forma:SolidPeso molecular:417.33VU0357017 hydrochloride
CAS:VU0357017 hydrochloride (ML071 hydrochloride) is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ± 172 nM; Pec50: 6.Fórmula:C18H28ClN3O3Pureza:99% - 99.97%Cor e Forma:SolidPeso molecular:369.89PHA 543613 hydrochloride
CAS:PHA-543613 hydrochloride, a potent α7 nicotinic receptor agonist, may treat schizophrenia-related cognitive deficits.Fórmula:C15H18ClN3O2Cor e Forma:SolidPeso molecular:307.78CCMI
CAS:CCMI (AVL-3288) is a potent and selective modulator of α7 nAChR-positive allosteric.Fórmula:C19H15Cl2N3O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:388.25Propiverine
CAS:Propiverine reduces muscle spasms by limiting calcium influx, targeting bladder smooth muscles, aiding OAB research.Fórmula:C23H29NO3Cor e Forma:SolidPeso molecular:367.48Solifenacin hydrochloride
CAS:Solifenacin Hcl is a muscarinic receptor antagonist.Fórmula:C23H27ClN2O2Pureza:98%Cor e Forma:SolidPeso molecular:398.93LY2886721
CAS:LY2886721, a BACE inhibitor, is used for the therapy of Alzheimer's Disease.Fórmula:C18H16F2N4O2SPureza:99% - 99.75%Cor e Forma:SolidPeso molecular:390.41CaM kinase II inhibitor TFA salt
CaM kinase II inhibitor TFA salt (Autocamtide-2-related inhibitory peptide (TFA)) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
Fórmula:C66H117F3N22O21Pureza:>99.99%Cor e Forma:SolidPeso molecular:1611.77TA-03
CAS:TA-03 (7-Meota) is a potent inhibitor of AChE in treatment of cognitive manifestation of AD.Fórmula:C14H16N2OPureza:99.22%Cor e Forma:SolidPeso molecular:228.29Ref: TM-T8585
1mg58,00€5mg116,00€10mg172,00€25mg281,00€50mg396,00€100mg537,00€200mg712,00€1mL*10mM (DMSO)104,00€Zacopride
CAS:Zacopride is a selective agonist of inward rectifier potassium current (I K1) channel, inhibiting ventricular arrhythmias without affecting atrial arrhythmias.Fórmula:C15H20ClN3O2Pureza:98%Cor e Forma:SolidPeso molecular:309.79Flutriafol
CAS:Flutriafol is a pesticide, demethylation inhibitor, and NMDA receptor agonist
Fórmula:C16H13F2N3OPureza:98.75%Cor e Forma:SolidPeso molecular:301.29Verubecestat tosylate
CAS:Verubecestat (MK-8931/SCH 900931) is a potent BACE1 inhibitor, promising for Alzheimer’s, reducing Aβ in CSF by up to 92%.Fórmula:C25H26N4O4S2Cor e Forma:SolidPeso molecular:510.627GSK163090
CAS:GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).Fórmula:C25H29N5OPureza:99.2%Cor e Forma:SolidPeso molecular:415.53Ref: TM-TQ0311
1mg34,00€2mg49,00€5mg75,00€10mg118,00€25mgA consultar50mgA consultar1mL*10mM (DMSO)82,00€1,1'-Methylenedi-2-naphthol
CAS:1,1'-Methylenedi-2-naphthol target CYP2C19 - cytochrome P450 family 2 subfamily C member 19 (human).Fórmula:C21H16O2Pureza:98.91%Cor e Forma:Light Pink To Light Brown Crystalline PowderPeso molecular:300.35Quipazine
CAS:Quipazine: 5-HT agonist, Ki 1.4 nM at 5-HT3R, anti-SARS-CoV-2 (EC50 31.64 μM), for neurological research.Fórmula:C13H15N3Cor e Forma:SolidPeso molecular:213.28CL 218872
CAS:CL 218872: selective α1 GABAA receptor agonist, anxiolytic, and anticonvulsant; Ki=130 nM for α1, less potent for α2-α6.Fórmula:C13H9F3N4Pureza:99.92%Cor e Forma:SolidPeso molecular:278.235-Benzyloxygramine
CAS:5-Benzyloxygramine blocks the Dopamin receptors and antagonizes the effects of 5-HT on the rat uterus and the rabbit ear.Fórmula:C18H20N2OPureza:99.13%Cor e Forma:SolidPeso molecular:280.36Pipamperone HCl
CAS:Pipamperone blocks 5-HT2A/B/C, D2/D3/D4, α1/α2 receptors; favors 5-HT2A/D4 over D2; negligible affinity for H1, mACh. Highly selective at low doses.Fórmula:C21H31ClFN3O2Cor e Forma:SolidPeso molecular:411.95idalopirdine
CAS:Idalopirdine (Lu AE58054), a selective 5-HT6 receptor antagonist( Ki : 0.83 nM),as a treatment for Alzheimer's disease.Fórmula:C20H19F5N2OPureza:99.73%Cor e Forma:SolidPeso molecular:398.37Ref: TM-T7103
1mg88,00€2mg118,00€5mg188,00€10mg254,00€25mg429,00€50mg630,00€100mg898,00€1mL*10mM (DMSO)187,00€Loreclezole hydrochloride
CAS:Loreclezole hydrochloride is an antiepileptic, enhancing GABA A receptors with β2/β3 subunits.Fórmula:C10H7Cl4N3Cor e Forma:SolidPeso molecular:310.99Renzapride hydrochloride
CAS:Renzapride is a 5-HT3 antagonist and 5-HT4 agonist. Renzapride also functions as a 5-HT2B antagonist and has some affinity for the 5-HT2A and 5-HT2C receptors.Fórmula:C16H23Cl2N3O2Cor e Forma:SolidPeso molecular:360.28BRL-15572 hydrochloride
CAS:BRL-15572 hydrochloride: selective h5-HT1D antagonist with high affinity; useful for studying h5-HT1D responses.Fórmula:C25H28Cl2N2OCor e Forma:SolidPeso molecular:443.41
