Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(642 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(2.998 produtos)
- BACE(37 produtos)
- Beta Amilóide(217 produtos)
- CaMK(73 produtos)
- COX(598 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(370 produtos)
- Gama-secretase(57 produtos)
- GluR(265 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(43 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(325 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5446 produtos de "Neurociência"
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Amperozide
CAS:Amperozide (FG 5606), an atypical antipsychotic, antagonizes 5-HT2A and modulates dopamine activity for schizophrenia treatment.Fórmula:C23H29F2N3OPureza:99.68%Cor e Forma:SolidPeso molecular:401.49Ref: TM-T23733
1mg87,00€5mg178,00€10mg295,00€25mg497,00€50mg708,00€100mg964,00€500mg1.918,00€1mL*10mM (DMSO)321,00€Indophagolin
CAS:Indophagolin: autophagy inhibitor, IC50 140 nM; blocks P2X4, P2X1, P2X3 receptors, IC50s 2.71, 2.40, 3.49 μM.Fórmula:C19H15BrClF3N2O3SPureza:99.76%Cor e Forma:SolidPeso molecular:523.75Ref: TM-T8946
1mg42,00€5mg82,00€10mg116,00€25mg188,00€50mg260,00€100mg366,00€200mg497,00€1mL*10mM (DMSO)95,00€Eltoprazine hydrochloride
CAS:Eltoprazine hydrochloride (DU 28853 hydrochloride) is a partial agonist at serotonin 5-HT1A, 5-HT1B, and 5-HT2B receptors (Ki value of 40, 52, and 81 nM,Fórmula:C12H17ClN2O2Pureza:99.35%Cor e Forma:SolidPeso molecular:256.73VU-1545
CAS:VU-1545 is mGlu5 positive allosteric modulator.Fórmula:C22H15FN4O3Pureza:98.8%Cor e Forma:SolidPeso molecular:402.38Bicuculline
CAS:Bicuculline, a plant-derived GABAA receptor antagonist, identified in 1932, reacts to light.Fórmula:C20H17NO6Pureza:98% - 99.99%Cor e Forma:Light Yellow PowderPeso molecular:367.35Loreclezole
CAS:Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors.Fórmula:C10H6Cl3N3Pureza:99.78%Cor e Forma:SolidPeso molecular:274.53Afloqualone
CAS:Afloqualone (HQ-495) is a GABA Receptor agonist with sedative and muscle-relaxant properties.Fórmula:C16H14FN3OPureza:99.72%Cor e Forma:SolidPeso molecular:283.3Pozanicline dihydrochloride
CAS:Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable agonist of nicotinic acetylcholine receptor (nAChR) (Ki = 16.7 nM)Fórmula:C11H18Cl2N2OPureza:98%Cor e Forma:SolidPeso molecular:265.18Azaphen dihydrochloride monohydrate
CAS:Azaphen dihydrochloride monohydrate is a 5-hydroxytryptamine reabsorption inhibitor with antidepressant activity and can be used to study neurological diseases.Fórmula:C16H23Cl2N5O2Pureza:99.85%Cor e Forma:SolidPeso molecular:388.29(-)-(S)-B-973B
CAS:(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.Fórmula:C24H26F2N6OPureza:99.52%Cor e Forma:SolidPeso molecular:452.5Umibecestat HCl
CAS:Umibecestat HCl (CNP520 HCl) is an efficient β-secretase (BACE1/BACE2) inhibitor that reduces Aβ levels in mice and rats.Fórmula:C19H16Cl2F7N5O2Pureza:99.92%Cor e Forma:SolidPeso molecular:550.26RS-67333
CAS:RS-67333 is a partial agonist of 5-HT4R with neuroprotective effects.Fórmula:C19H29ClN2O2Pureza:99.24%Cor e Forma:SolidPeso molecular:352.9Avagacestat
CAS:Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM,Fórmula:C20H17ClF4N4O4SPureza:98.87% - 99.73%Cor e Forma:SolidPeso molecular:520.89Ref: TM-T6249
1mg38,00€5mg77,00€10mg116,00€25mg215,00€50mg310,00€100mg450,00€200mg605,00€1mL*10mM (DMSO)88,00€γ-Mangostin
CAS:Gamma-Mangostin (Normangostin) has free radical scavenging activity, and antiproliferative and apoptotic activity. Gamma-Mangostin is an antihypertensive agent.Fórmula:C23H24O6Pureza:98.55% - 99.08%Cor e Forma:SolidPeso molecular:396.43SR 57227 hydrochloride
CAS:SR 57227A (SR 57227 hydrochloride) is a potent, orally active and selective 5-HT3 receptor agonist. It with ability to cross the blood brain barrier.Fórmula:C10H14ClN3·HClPureza:99.89%Cor e Forma:SolidPeso molecular:248.15Pergolide mesylate
CAS:Pergolide mesylate (LY127809), a dopamine agonist for Parkinson's and hyperprolactinemia, was withdrawn for heart valve risk.Fórmula:C20H30N2O3S2Pureza:99.70%Cor e Forma:White To Off-White SolidPeso molecular:410.59Chlorprothixene
CAS:Chlorprothixene (Truxal) is a typical antipsychotic drug of the thioxanthene class, which was the first of the series to be synthesized.Fórmula:C18H18ClNSPureza:98.77% - 99.756%Cor e Forma:Pale Yellow Crystals SolidPeso molecular:315.86NGB 2904
CAS:NGB 2904 is a potent and selective antagonist of dopamine D3 receptor. NGB2904 potently antagonizes mitogenesis stimulated by quinpirole (IC50 = 6.8 nM).Fórmula:C28H29Cl2N3OPureza:98.79%Cor e Forma:SolidPeso molecular:494.46Ref: TM-T28167
2mg38,00€5mg55,00€10mg86,00€25mg155,00€50mg264,00€100mg374,00€500mgA consultar1mL*10mM (DMSO)72,00€Piperacetazine
CAS:Piperacetazine (Piperacetazinum), an antipsychotic prodrug, is used forschizophrenia.Fórmula:C24H30N2O2SPureza:99.9% - 99.92%Cor e Forma:SolidPeso molecular:410.57S 14506 HCl
CAS:S 14506 HCl: Strong 5-HT1A agonist; pKi - 9.0 (5-HT1A), 6.6 (5-HT1B/C), <6.0 (5-HT3).Fórmula:C24H26FN3O2Cor e Forma:SolidPeso molecular:407.48Succinylcholine Chloride Dihydrate
CAS:Succinylcholine Chloride Dihydrate (Succinyldicholine dichloride) is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.
Fórmula:C14H30N2O4·2Cl·2H2OPureza:99.87%Cor e Forma:White SolidPeso molecular:397.34Metoclopramide
CAS:Metoclopramide: dopamine D2 antagonist, treats nausea, vomiting, gastroparesis, GERD; safe for pregnancy.Fórmula:C14H22ClN3O2Pureza:99.75%Cor e Forma:SolidPeso molecular:299.80MCI-225
CAS:MCI-225 is a selective inhibitor of NA reuptake with 5-HT3 receptor antagonism.Fórmula:C17H17FN4SPureza:99.32%Cor e Forma:SolidPeso molecular:328.4Arecaidine hydrochloride
CAS:Arecaidine hydrochloride may have carcinogenesis.Fórmula:C7H12ClNO2Pureza:99.69% - ≥95%Cor e Forma:SolidPeso molecular:177.63Ref: TM-T5799
2mg34,00€5mg48,00€10mg67,00€25mg100,00€50mg149,00€100mg213,00€200mg316,00€1mL*10mM (DMSO)49,00€Tasimelteon
CAS:Tasimelteon (BMS-214778) is a melatonin receptor agonist that is used for the treatment of non-24 hour sleep-wake disorder in blind individuals.Fórmula:C15H19NO2Pureza:98.93% - 99.93%Cor e Forma:SolidPeso molecular:245.32ARN2966
CAS:ARN2966 is an inhibitor of amyloid precursor protein (APP)and amyloid-β (Aβ) secretion.Fórmula:C12H12N2OPureza:99.52% - 99.86%Cor e Forma:SolidPeso molecular:200.24Ref: TM-T7490
1mg37,00€5mg79,00€10mg119,00€25mg235,00€50mg378,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)87,00€QNZ46
CAS:QNZ46 is a NR2C/NR2D-selective NMDA receptor non-competitive antagonist.
Fórmula:C24H17N3O6Pureza:99.65%Cor e Forma:SolidPeso molecular:443.41Syn-Ake acetate
CAS:Syn-Ake acetate (Dipeptide diaminobutyroyl benzylamide) is a muscarinic acetylcholine receptor antagonist.Fórmula:C19H29N5O3·2(C2H4O2)Pureza:99.60%Cor e Forma:SolidPeso molecular:495.58Elenbecestat free base
CAS:Elenbecestat (E2609) is a BACE1 inhibitor that reduces Aβ peptide formation, potentially preventing amyloid plaques in the brain.Fórmula:C19H15F6N5O2SCor e Forma:SolidPeso molecular:491.41Donitriptan Mesylate
CAS:Donitriptan Mesylate, a 5-HT1B/1D agonist, is used potentially for the treatment of migraines.Fórmula:C24H29N5O5SCor e Forma:SolidPeso molecular:499.58Melitracen
CAS:Melitracen is a tricyclic antidepressant.Fórmula:C21H25NCor e Forma:SolidPeso molecular:291.43Dihydroergotoxine mesylate
CAS:Dihydroergotoxine mesylate (Ergoloid mesylates) is mainly used to improve symptoms and physical symptoms of mental degeneration related to aging.Fórmula:C20H29N3O5SPureza:99.39% - ≥95%Cor e Forma:SolidPeso molecular:423.53Basmisanil
CAS:Basmisanil (RG1662) is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for theFórmula:C21H20FN3O5SPureza:99.21% - 99.42%Cor e Forma:SolidPeso molecular:445.46Ref: TM-T7165
2mg35,00€5mg52,00€10mg74,00€25mg116,00€50mg187,00€100mg356,00€500mg802,00€1mL*10mM (DMSO)49,00€Lerisetron
CAS:Lerisetron is an antagonist of serotonin type 3 (5-HT3) receptor, with antiemetic activity.Fórmula:C18H20N4Pureza:99.15% - 99.82%Cor e Forma:SolidPeso molecular:292.38(RS)-MCPG
CAS:(RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist.Fórmula:C10H11NO4Pureza:99.96%Cor e Forma:SolidPeso molecular:209.2Isoflurane
CAS:Isoflurane (Forane) is a stable, non-explosive inhalation anesthetic that has been reported to induce caspase-3 activation.Fórmula:C3H2ClF5OPureza:98%Cor e Forma:Clear Colorless Liquid LiquidPeso molecular:184.49PSEM 89S TFA
CAS:PSEM 89S TFA is a brain-penetrant and selective ion channels agonist, and is orthogonally selective for Q79G and L141F, respectively.Fórmula:C18H23F3N2O5Pureza:99.9%Cor e Forma:SolidPeso molecular:404.38IGS-1.76
CAS:IGS-1.76 binds strongly to hNCS-1, modulates its Ric8a interaction, and inhibits the hNCS-1/Ric8a complex.Fórmula:C22H18N2OSPureza:98.18% - 98.56%Cor e Forma:SolidPeso molecular:358.46SKF-83566
CAS:SKF-83566: Blood-brain permeable, orally active D1 dopamine antagonist; weaker 5-HT2 antagonist, Ki=11 nM.Fórmula:C17H18BrNOPureza:95.00% - 99.82%Cor e Forma:SolidPeso molecular:332.23Lorediplon
CAS:Lorediplon is a novel hypnotic drug acting as a GABAA receptor modulator, differentially active at the α1-subunit, associated with promoting sleep.Fórmula:C20H15FN4O2SPureza:99.12% - 99.19%Cor e Forma:SolidPeso molecular:394.42VU0155094
CAS:VU0155094 (ML 397) is a positive allosteric modulator with differential activity at the various group III mGluRs.
Fórmula:C24H24N2O4SPureza:97.21%Cor e Forma:SolidPeso molecular:436.52Orexin 2 Receptor Agonist
CAS:Orexin 2 Receptor Agonist (OX2R) is an effective (EC50: 23 nM) and OX2R-selective (OX1R/OX2R EC50 ratio: 70) agonist.Fórmula:C32H34N4O5SPureza:98.26% - 99.43%Cor e Forma:SolidPeso molecular:586.7Ref: TM-T3177
2mg39,00€5mg60,00€10mg75,00€25mg130,00€50mg220,00€100mg323,00€200mg447,00€1mL*10mM (DMSO)77,00€Suritozole
CAS:Suritozole (MDL-26479) is a negative modulator at the gamma-aminobutyric acidA (GABAA) receptorFórmula:C10H10FN3SPureza:99.25%Cor e Forma:SolidPeso molecular:223.27Ref: TM-T8568
1mg58,00€5mg116,00€10mg172,00€25mg281,00€50mg396,00€100mg537,00€200mg712,00€1mL*10mM (DMSO)104,00€VU 0357121
CAS:VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.Fórmula:C17H17F2NO2Pureza:99% - >99.99%Cor e Forma:SolidPeso molecular:305.32Cerlapirdine
CAS:Cerlapirdine (PF-05212365), a 5-HT6 receptor antagonist, is in trials for Alzheimer's and schizophrenia cognition issues.Fórmula:C22H23N3O3SPureza:98.77%Cor e Forma:SolidPeso molecular:409.5Ref: TM-T30798
1mg81,00€5mg170,00€10mg274,00€25mg543,00€50mg780,00€100mg1.074,00€1mL*10mM (DMSO)198,00€Pempidine HCl
CAS:Pempidine HCl, a nicotinic antagonist and former hypertension treatment, now mainly serves as a lab tool.Fórmula:C10H22ClNCor e Forma:SolidPeso molecular:191.74SIB-1757
CAS:SIB-1757 (6-methyl-2-[(E)-phenyldiazenyl]pyridin-3) is a selective antagonist of mGlu5 metabotropic glutamate receptor subtype (hmGlu5, IC50 : 0.4 μM)Fórmula:C12H11N3OPureza:97.37%Cor e Forma:SolidPeso molecular:213.24Vilazodone Hydrochloride
CAS:Vilazodone Hydrochloride (EMD 68843) , a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of theFórmula:C26H27N5O2·HClPureza:99.56% - >99.99%Cor e Forma:SolidPeso molecular:477.99VU0155041
CAS:VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).Fórmula:C14H15Cl2NO3Pureza:99.52% - 99.56%Cor e Forma:SolidPeso molecular:316.18Ref: TM-T3565
2mg38,00€5mg55,00€10mg80,00€25mg138,00€50mg178,00€100mg285,00€200mg413,00€1mL*10mM (DMSO)60,00€Metoclopramide hydrochloride hydrate
CAS:Metoclopramide hydrochloride hydrate (Metoclopramide monohydrochloride monohydrate) is a dopamine D2 antagonist that is a drug used for digestive dysfunction.Fórmula:C14H25Cl2N3O3Pureza:99.33%Cor e Forma:SolidPeso molecular:354.27
