Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(642 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.002 produtos)
- BACE(37 produtos)
- Beta Amilóide(220 produtos)
- CaMK(73 produtos)
- COX(598 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(370 produtos)
- Gama-secretase(60 produtos)
- GluR(266 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(43 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(41 produtos)
- Receptor opioide(325 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5474 produtos de "Neurociência"
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JH-II-127
CAS:JH-II-127 is an oral LRRK2 inhibitor with IC50s: 6.6 nM (WT), 2.2 nM (G2019S), 47.7 nM (A2016T).Fórmula:C19H21ClN6O3Pureza:98.32%Cor e Forma:SolidPeso molecular:416.86Ref: TM-T7155
2mg43,00€5mg66,00€10mg96,00€25mg166,00€50mg259,00€100mg366,00€200mg520,00€1mL*10mM (DMSO)73,00€3-AQC
CAS:3-AQC is a competitive antagonist of 5-HT3.Fórmula:C20H21N5O4Pureza:99.45%Cor e Forma:SolidPeso molecular:395.41PHA 568487
CAS:PHA 568487: α-7 nAChR agonist, rapid brain uptake, lessens oxidative stress & neuroinflammation.Fórmula:C20H24N2O7Cor e Forma:SolidPeso molecular:404.419CGP52432
CAS:CGP52432 is a very potent antagonist of GABAB receptors (IC50 = 85 nM).Fórmula:C15H24Cl2NO4PPureza:98.75%Cor e Forma:SolidPeso molecular:384.245-Benzyloxygramine
CAS:5-Benzyloxygramine blocks the Dopamin receptors and antagonizes the effects of 5-HT on the rat uterus and the rabbit ear.Fórmula:C18H20N2OPureza:99.13%Cor e Forma:SolidPeso molecular:280.36PFE-360
CAS:PFE-360 (PF-06685360) is a potent and selective inhibitor of LRRK2 kinase (IC50: 2.3 nM in vivo).
Fórmula:C16H16N6OPureza:98.14% - 99.73%Cor e Forma:SolidPeso molecular:308.34SB-334867 free base
CAS:SB-334867 free base (SB334867A free base) is a selective orexin-1 (OX1) receptor antagonist.Fórmula:C17H13N5O2Pureza:99.67% - >99.99%Cor e Forma:SolidPeso molecular:319.32Ref: TM-T6140
2mg39,00€5mg66,00€10mg94,00€25mg152,00€50mg215,00€100mg319,00€200mg475,00€1mL*10mM (DMSO)73,00€KN-92
CAS:KN-92 is an inactive analog of the CaM kinase II inhibitor KN 93.Fórmula:C24H25ClN2O3SCor e Forma:SolidPeso molecular:456.98Semagacestat
CAS:Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM).Fórmula:C19H27N3O4Pureza:97.1% - 99.9%Cor e Forma:SolidPeso molecular:361.44SCH-23390 hydrochloride
CAS:SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).Fórmula:C17H19Cl2NOPureza:98% - 99.83%Cor e Forma:SolidPeso molecular:324.24Ref: TM-T4369
1mg39,00€2mg50,00€5mg78,00€10mg97,00€25mg195,00€50mg369,00€100mg550,00€1mL*10mM (DMSO)78,00€AMN082 free base
CAS:AMN082 free base is a metabotropic glutamate receptor 7 allosteric agonist.Fórmula:C28H28N2Pureza:97.75% - 97.79%Cor e Forma:SolidPeso molecular:392.54Ref: TM-T21935L
5mg50,00€10mg74,00€25mg135,00€50mg212,00€100mg340,00€200mg475,00€1mL*10mM (DMSO)52,00€Verubecestat TFA
CAS:Verubecestat (MK-8931/SCH 900931), a potent BACE1 inhibitor, shows promise for Alzheimer's, cuts Aβ CSF levels by 92%.Fórmula:C19H18F5N5O5SCor e Forma:SolidPeso molecular:523.435Tasimelteon
CAS:Tasimelteon (BMS-214778) is a melatonin receptor agonist that is used for the treatment of non-24 hour sleep-wake disorder in blind individuals.Fórmula:C15H19NO2Pureza:98.93% - 99.93%Cor e Forma:SolidPeso molecular:245.32Myristicin
CAS:Myristicin is a natural spice extract with antibacterial, anti-inflammatory, and hepatoprotective properties, and can induce apoptosis.
Fórmula:C11H12O3Pureza:99.828%Cor e Forma:LiquidPeso molecular:192.21Cyclopentolate Hydrochloride
CAS:Cyclopentolate Hydrochloride is a muscarinic acetylcholine receptors antagonist with Kis of 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively.Fórmula:C17H26ClNO3Pureza:99.91%Cor e Forma:SolidPeso molecular:327.858-Hydroxy-DPAT hydrobromide
CAS:8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) (8-OH-DPAT hydrobromide) is a potent and selective 5-HT1A agonist with a pIC50 of 8.19.Fórmula:C16H26BrNOPureza:98.90% - 99.96%Cor e Forma:SolidPeso molecular:328.292'MeO6MF
CAS:2'MeO6MF is a brain-penetrant positive allosteric modulator at α2β1γ2L and all α1-containing GABAA receptors.It offers neuroprotection and improved functionalFórmula:C17H14O3Pureza:99.28% - 99.63%Cor e Forma:SolidPeso molecular:266.29Ref: TM-T8887
1mg49,00€5mg102,00€10mg152,00€25mg243,00€50mg340,00€100mg460,00€200mg627,00€1mL*10mM (DMSO)96,00€Encenicline
CAS:Encenicline (EVP-6124), a selective α7 nAChRs agonist, targets cognitive impairment in schizophrenia and Alzheimer's.Fórmula:C16H17ClN2OSPureza:99.20%Cor e Forma:SolidPeso molecular:320.84Ref: TM-T7193
1mg70,00€5mg133,00€10mg207,00€25mg349,00€50mg495,00€100mg675,00€200mg888,00€1mL*10mM (DMSO)144,00€SSD114 HCl
CAS:SSD114 is a novel GABAB receptor positive allosteric modulator.Fórmula:C18H21ClF3N3OPureza:99.03% - 99.95%Cor e Forma:SolidPeso molecular:387.83Ref: TM-T4522
2mg34,00€5mg50,00€10mg75,00€25mg111,00€50mg172,00€100mg290,00€200mg419,00€1mL*10mM (DMSO)46,00€Pipequaline hydrochloride
CAS:Pipequaline hydrochloride (PK-8165 hydrochloride) is an anticonflict & anticonvulsant quinoline derivative.Fórmula:C22H25ClN2Pureza:99.46%Cor e Forma:SolidPeso molecular:352.9Amyloid β-Protein 10-20 acetate
Amyloid β-Protein 10-20 acetate (Amyloid β-Protein 10-20 acetate (152286-31-2 free base)) is a fragment of Amyloid-β peptide, maybe used in the research ofFórmula:C73H103N17O18Pureza:97.23%Cor e Forma:SolidPeso molecular:1506.65LRRK2-IN-1
CAS:LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.Fórmula:C31H38N8O3Pureza:98% - 98.82%Cor e Forma:SolidPeso molecular:570.69γ-Mangostin
CAS:Gamma-Mangostin (Normangostin) has free radical scavenging activity, and antiproliferative and apoptotic activity. Gamma-Mangostin is an antihypertensive agent.Fórmula:C23H24O6Pureza:98.55% - 99.08%Cor e Forma:SolidPeso molecular:396.43SKF-83566
CAS:SKF-83566: Blood-brain permeable, orally active D1 dopamine antagonist; weaker 5-HT2 antagonist, Ki=11 nM.Fórmula:C17H18BrNOPureza:95.00% - 99.82%Cor e Forma:SolidPeso molecular:332.23IGS-1.76
CAS:IGS-1.76 binds strongly to hNCS-1, modulates its Ric8a interaction, and inhibits the hNCS-1/Ric8a complex.Fórmula:C22H18N2OSPureza:98.18% - 98.56%Cor e Forma:SolidPeso molecular:358.46Cromoglicic acid
CAS:Cromoglicic acid prevents the release of inflammatory chemicals such as histamine from mast cells.
Fórmula:C23H16O11Pureza:99.55% - >99.99%Cor e Forma:Colorless Crystals From Ethanol + Ether Physical Description Solid (Ntp 1992)Peso molecular:468.37Coluracetam
CAS:Coluracetam (MKC-231)(MKC-231) is a Choline Uptake Enhancer.Fórmula:C19H23N3O3Pureza:99.96%Cor e Forma:SolidPeso molecular:341.4Miridesap
CAS:Miridesap (GSK2315698) rapidly depletes SAP in blood, cerebrospinal fluid, and amyloid deposits via liver clearance.Fórmula:C16H24N2O6Pureza:≥95%Cor e Forma:SolidPeso molecular:340.37MDL 100009
CAS:MDL 100009, the S-enantiomer of MDL 100151 and the opposite enantiomer of MDL 100907, is a selective antagonist of 5-HT2A.Fórmula:C22H28FNO3Pureza:98.96%Cor e Forma:SolidPeso molecular:373.46Ref: TM-T22359
1mg99,00€5mg187,00€10mg280,00€25mg434,00€50mg585,00€100mg775,00€200mg1.054,00€1mL*10mM (DMSO)222,00€Vortioxetine
CAS:Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders.Fórmula:C18H22N2SPureza:99.34% - 99.34%Cor e Forma:SolidPeso molecular:298.45Ref: TM-T2395
1g477,00€10mg48,00€25mg65,00€50mg90,00€100mg117,00€200mg203,00€500mg333,00€1mL*10mM (DMSO)46,00€SKF89976A HCl
CAS:SKF89976A: GABA uptake inhibitor, selective for GAT-1, passes blood-brain barrier, active in vivo (IC50: 0.13 μM hGAT-1).Fórmula:C22H25NO2Cor e Forma:SolidPeso molecular:335.44Pempidine
CAS:Pempidine (1,2,2,6,6-Pentamethylpiperidine) is a nicotinic antagonist, has been used as a ganglionic blocker in the treatment of hypertension.Fórmula:C10H21NPureza:98.18% - 99.28%Cor e Forma:Colorless - Light Yellow Clear LiquidPeso molecular:155.28Eptapirone
CAS:Eptapirone (F 11440) is a highly effective and selective 5-HT1A receptor agonist with marked antidepressant and anxiolytic potential.Fórmula:C16H23N7O2Pureza:99.39% - 99.65%Cor e Forma:SolidPeso molecular:345.4LP-211
CAS:LP-211 is a brain penetrant selective agonist for a 5-HT7 receptor (Ki: 0.58 nM), and >300-fold selectivity over the 5-HT1A receptor.Fórmula:C30H34N4OPureza:98.65%Cor e Forma:SolidPeso molecular:466.62Ref: TM-T5387
2mg44,00€5mg66,00€10mg90,00€25mg170,00€50mg289,00€100mg462,00€200mg658,00€1mL*10mM (DMSO)73,00€Metoclopramide
CAS:Metoclopramide: dopamine D2 antagonist, treats nausea, vomiting, gastroparesis, GERD; safe for pregnancy.Fórmula:C14H22ClN3O2Pureza:99.75%Cor e Forma:SolidPeso molecular:299.80RU 24969 free base
CAS:RU 24969 (5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole) is a selective agonist of 5-HT1A and 5-HT1B receptors.Fórmula:C14H16N2OPureza:97.38%Cor e Forma:SolidPeso molecular:228.29Acotiamide hydrochloride
CAS:Acotiamide hydrochloride, an oral AChE inhibitor (IC50: 1.79 μM), boosts gastric movement and treats functional dyspepsia.Fórmula:C21H31ClN4O5SCor e Forma:SolidPeso molecular:487.01Perospirone hydrochloride
CAS:Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia.Fórmula:C23H31ClN4O2SPureza:99.37%Cor e Forma:White SolidPeso molecular:463Gaboxadol hydrochloride
CAS:Gaboxadol (hydrochloride) is a GABAA receptor agonist.Fórmula:C6H9ClN2O2Pureza:99.39%Peso molecular:176.601FPS-ZM1
CAS:FPS-ZM1 is a high-affinity RAGE specific inhibitor that blocks Aβ binding to the V domain of RAGE.Fórmula:C20H22ClNOPureza:99.32% - 99.52%Cor e Forma:SolidPeso molecular:327.85Ref: TM-T3259
5mg48,00€10mg54,00€25mg96,00€50mg140,00€100mg207,00€200mg333,00€500mg560,00€1mL*10mM (DMSO)50,00€RAGE antagonist peptide acetate
RAGE antagonist peptide acetate blocks RAGE-ligands like HMGB-1, has anti-tumor, and anti-inflammatory effects.Fórmula:C59H105N13O19SPureza:97.17%Cor e Forma:SolidPeso molecular:1332.61Mivacurium dichloride
CAS:Mivacurium dichloride: non-depolarizing, quick-acting muscle relaxant for minor surgeries and tracheal intubation.Fórmula:C58H80Cl2N2O14Pureza:99.2% - 99.48%Cor e Forma:Off-White SolidPeso molecular:1100.17Ref: TM-T22371
2mg46,00€5mg65,00€10mg94,00€25mg123,00€50mg188,00€100mg286,00€200mg434,00€1mL*10mM (DMSO)90,00€6-fluoro-DL-Tryptophan
CAS:6-fluoro-DL-Tryptophan is an inhibitor of serotonin (5-HT) synthesis.Fórmula:C11H11FN2O2Pureza:99.25%Cor e Forma:Off-White PowderPeso molecular:222.22Pirenperone
CAS:Pirenperone is a putative 5-HT2 receptor antagonist with the central antiserotonergic and antidopaminergic action.Fórmula:C23H24FN3O2Pureza:99.2%Cor e Forma:SolidPeso molecular:393.45Pitofenone
CAS:Pitofenone is an inhibitor of the acetylcholinesterase activity from bovine erythrocytes and electric eel.Fórmula:C22H25NO4Cor e Forma:SolidPeso molecular:367.44FTIDC
CAS:FTIDC: potent, selective mGluR1 allosteric antagonist, weak on mGluR5. IC50: human 5.8 nM, mouse 3.1 nM. Noncompetitive.Fórmula:C18H23FN6OPureza:94.58%Cor e Forma:SolidPeso molecular:358.41Ref: TM-T3483
1mg100,00€2mg145,00€5mg215,00€10mg340,00€25mg565,00€50mg797,00€100mg1.071,00€1mL*10mM (DMSO)236,00€Isonipecotic acid
CAS:Isonipecotic acid (4-Piperidinecarboxylic acid) is a heterocyclic compound. Isonipecotic acid mainly characterized as a GABAA receptor partial agonist.Fórmula:C6H11NO2Pureza:99.82%Cor e Forma:White To Faint Pink-Beige PowderPeso molecular:129.16Piperidolate hydrochloride
CAS:Piperidolate hydrochloride, an antimuscarinic, reduces acetylcholine-induced intestinal spasms in rats and dogs.Fórmula:C21H26ClNO2Pureza:99.5%Cor e Forma:SolidPeso molecular:359.89Dasotraline hydrochloride
CAS:Dasotraline hydrochloride, a dopamine, norepinephrine, and serotonin reuptake inhibitor with IC50s: 4, 6, 11 nM.Fórmula:C16H16Cl3NPureza:98.92% - 99.6%Cor e Forma:SolidPeso molecular:328.66Adiphenine
CAS:Adiphenine is an inhibitor of nicotinic receptors.Fórmula:C20H25NO2Cor e Forma:SolidPeso molecular:311.42
