Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(993 produtos)
- ACK(1 produtos)
- AChR(612 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.004 produtos)
- BACE(36 produtos)
- Beta Amilóide(216 produtos)
- CaMK(71 produtos)
- COX(592 produtos)
- Receptor de Dopamina(433 produtos)
- Receptor GABA(355 produtos)
- Gama-secretase(63 produtos)
- GluR(261 produtos)
- GlyT(24 produtos)
- Receptor de Histamina(381 produtos)
- LRRK2(41 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(15 produtos)
- Receptor OX(41 produtos)
- Receptor opioide(310 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5516 produtos de "Neurociência"
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Tedatioxetine hydrobromide
CAS:Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) is a serotonin-norepinephrine-dopamine reuptake inhibitor and 5-HT2A receptor antagonist.Fórmula:C18H22BrNSPureza:99.65%Cor e Forma:SolidPeso molecular:364.34Belaperidone
CAS:Belaperidone, an antipsychotic, resembles clozapine, binds D(4) and 5-HT(2A) receptors, minimally extends Q-T without causing arrhythmias.Fórmula:C22H22FN3O2Cor e Forma:SolidPeso molecular:379.43Adenylyl cyclase type 2 agonist-1
CAS:<p>Potent AC2 agonist with an EC50 of 90 nM, potential for respiratory disease treatment.</p>Fórmula:C27H17BrClNO5Cor e Forma:SolidPeso molecular:550.78RO5488608
CAS:RO5488608 is a new type of high-efficiency mGlu2/3 NAM.Fórmula:C23H17F3N2O4SCor e Forma:SolidPeso molecular:474.455-HT7 agonist 1
CAS:<p>5-HT7 agonist 1 (4-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-1H-indole) is a selective agonist of 5-HT7 (IC50 = 222.93 nM).</p>Fórmula:C19H20ClN3Pureza:98.61%Cor e Forma:SolidPeso molecular:325.84Aβ-IN-5
CAS:Aβ-IN-5 (Compound e12) is an orally active Aβ aggregation inhibitor that also inhibits AChE and BuChE with IC50 values of 21.29 μM and 1.32 μM, respectively.Fórmula:C21H20N2O3Cor e Forma:SolidPeso molecular:348.4A 841720
CAS:Potent, selective mGlu1 antagonist A-841720; IC50: 10 nM; 34x selectivity vs mGlu5; analgesic potential.Fórmula:C17H21N5OSCor e Forma:SolidPeso molecular:343.45BChE-IN-11
CAS:BChE-IN-11: potent, selective, non-competitive BChE inhibitor; IC50=2.1μM; used in AD research.Fórmula:C22H18O4Cor e Forma:SolidPeso molecular:346.38NPEC-caged-LY379268
CAS:<p>NPEC-caged-LY379268 is a type II mGluR agonist [1].</p>Fórmula:C16H16N2O9Cor e Forma:SolidPeso molecular:380.31Anabasine hydrochloride
CAS:neuronal nicotinic ACh receptor partial agonistFórmula:C10H15ClN2Pureza:98%Cor e Forma:White To Off-White SolidPeso molecular:198.693Pheniprazine
CAS:<p>Pheniprazine, a potent and long-acting monoamine oxidase inhibitor, shows promise for depression research.</p>Fórmula:C9H14N2Cor e Forma:SolidPeso molecular:150.22(Rac)-WAY-161503
CAS:(Rac)-WAY-161503 is a selective and high-affinity agonist of the 5-HT2C receptor (Ki: 4 nM; EC50: 12 nM), with anti-obesity and antidepressant effects.Fórmula:C11H11Cl2N3OPureza:99.51%Cor e Forma:SolidPeso molecular:272.13PD-102807
CAS:PD-102807 is a selective and competitive M4 muscarinic receptor antagonist for Parkinson's disease research, inhibit airway smooth muscle (ASM) contraction.Fórmula:C23H24N2O4Pureza:98.90%Cor e Forma:SolidPeso molecular:392.45Ethybenztropine
CAS:<p>Ethybenztropine is an anticholinergic used as an antiparkinsonian agent and may also act as a dopamine reuptake inhibitor.</p>Fórmula:C22H27NOPureza:98%Cor e Forma:SolidPeso molecular:321.46Zicronapine
CAS:Zicronapine (LU 31-130), an atypical antipsychotic with monoaminergic action, targets dopamine D1/D2 and serotonin 5HT2A.Fórmula:C22H27ClN2Cor e Forma:SolidPeso molecular:354.925-HT7 agonist 2
CAS:Potent 5-HT7 agonist with 28.7 nM IC50; promising for CNS disorder research.Fórmula:C23H29N3OCor e Forma:SolidPeso molecular:363.5Memoquin
CAS:Memoquin is a multi-target-directed ligand for the therapy of Alzheimer's disease.Fórmula:C38H56N4O4Cor e Forma:SolidPeso molecular:632.88PHCCC(4Me)
CAS:THCCC, a PHCCC analog, is a dual metabotropic glutamate receptor 2/3 negative/positive allosteric modulator.Fórmula:C18H16N2O3Cor e Forma:SolidPeso molecular:308.33mHTT-IN-2
CAS:mHTT-IN-2 (compound 27) is a potent inhibitor of mutant huntingtin protein (mHTT), with an EC50 value of 0.066 μM.Fórmula:C20H22FN7OPureza:98%Cor e Forma:SolidPeso molecular:395.43E2730
CAS:E2730 is a non-competitive GABA transporter 1 (GAT1) inhibitor with anti-epileptic activity, useful in studying neurological disorders.Fórmula:C9H8F4N2O2SPureza:98.22% - 98.54%Cor e Forma:SolidPeso molecular:284.23AMPA receptor modulator-4
CAS:AMPA Receptor Modulator-4, a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (BTD), serves as an orally active positive allosteric modulator of the AMPAFórmula:C11H12ClFN2O2SPureza:98%Cor e Forma:SolidPeso molecular:290.74BChE-IN-7
CAS:BChE-IN-7 inhibits AChE/BChE selectively and reversibly; IC50 for BChE: 0.06 μM; crosses blood-brain barrier, protects neurons from Aβ toxicity.Fórmula:C21H24N2O2Cor e Forma:SolidPeso molecular:336.43MAO-B-IN-22
CAS:MAO-B-IN-22 (compound 6h) represents a powerful MAO-B inhibitor, boasting an IC50 value of 0.014 μM, and exhibits high antioxidant activity alongside effectiveFórmula:C20H18FNO2Pureza:98%Cor e Forma:SolidPeso molecular:323.36MAO-B-IN-23
CAS:<p>MAO-B-IN-23, also known as Compound 11f, is a reversible and competitive monoamine oxidase B (MAO-B) inhibitor with an IC50 value of 1.44 μM and a Ki of 0.51 μM</p>Fórmula:C19H18BrNOPureza:98%Cor e Forma:SolidPeso molecular:356.26Anti-inflammatory agent 56
CAS:Anti-inflammatory agent 56 (Compound 9), a selective COX-2 inhibitor with an IC50 of 0.54 μM, exhibits anti-oxidant and anti-inflammatory properties byFórmula:C21H15F3N4O4SPureza:98%Cor e Forma:SolidPeso molecular:476.43Ambutonium bromide
CAS:Ambutonium bromide is an antagonist of acetylcholine.Fórmula:C20H27BrN2OPureza:98%Cor e Forma:SolidPeso molecular:391.35SB 207710
CAS:SB 207710 is a selective and high affinity antagonist of 5-HT4 receptor.Fórmula:C19H27IN2O4Cor e Forma:SolidPeso molecular:474.33Bornaprine
CAS:Bornaprine is an anticholinergic drug used to treat Parkinson's disease due to inhibition of muscarinic or nicotinic transmission.Fórmula:C21H31NO2Cor e Forma:SolidPeso molecular:329.48CP-809101
CAS:CP-809101 is an effective and selective 5-HT2C receptor agonist (pEC50: 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors).Fórmula:C15H17ClN4OPureza:98%Cor e Forma:SolidPeso molecular:304.77Caroxazone
CAS:Caroxazone is an antidepressant drug, monoamine oxidase inhibitor (MAOI) that is irreversible and nonselective meanwhile.Fórmula:C10H10N2O3Cor e Forma:SolidPeso molecular:206.2Bitopertin (R enantiomer)
CAS:Bitopertin R enantiomer (RG1678 R enantiomer) is the R-enantiomer of Bitopertin.Fórmula:C21H20F7N3O4SPureza:98%Cor e Forma:SolidPeso molecular:543.46SB-269970
CAS:SB-269970 is a antagonist of 5-HT7 receptor(pKi of 8.3).Fórmula:C18H28N2O3SPureza:98%Cor e Forma:SolidPeso molecular:352.49Phenoxyacetone
CAS:Phenoxyacetone (NSC-1876) is an inhibitor of acetylcholinesterase.Fórmula:C9H10O2Pureza:98.21%Cor e Forma:Clear Light Yellow LiquidPeso molecular:150.17(R)-Oxybutynin
CAS:<p>(R)-Oxybutynin: oral muscarinic blocker with antispasmodic effects, used in neurogenic bladder research.</p>Fórmula:C22H31NO3Cor e Forma:SolidPeso molecular:357.49Elucaine
CAS:Elucaine is an antagonist of the muscarinic acetylcholine receptor. It has anti-ulcerative activity.Fórmula:C19H23NO2Pureza:98%Cor e Forma:SolidPeso molecular:297.39MAO-B-IN-12
CAS:MAO-B-IN-12 (16c) is a potent MAO-B inhibitor with an IC50 of 1.3 μM and has neuroprotective properties.Fórmula:C22H30O4Cor e Forma:SolidPeso molecular:358.47Antioxidant agent-2
CAS:Antioxidant agent-2 (3c), BBB-permeable, selectively chelates metals; shows neuroprotection, fights liver damage in Alzheimer's research.Fórmula:C23H26N2O7Cor e Forma:SolidPeso molecular:442.46VU0455691
CAS:VU0455691 is a selective M1 Muscarinic Receptor Allosteric Modulators.Fórmula:C24H25N5O3SPureza:98%Cor e Forma:SolidPeso molecular:463.55LY314228
CAS:<p>LY314228 is an antagonist of 5-HT2A receptor.</p>Fórmula:C20H24N4O3Cor e Forma:SolidPeso molecular:368.43Remeglurant
CAS:Remeglurant is used as a selective antagonist of the mGlu5 receptor.Fórmula:C17H15BrN4OCor e Forma:SolidPeso molecular:371.23Dihydro Donepezil
CAS:Dihydro Donepezil (Dihydro E2020), a Donepezil metabolite, is a potent AChE inhibitor (IC50: hAChE 11.6 nM, bAChE 8.12 nM).Fórmula:C24H31NO3Cor e Forma:SolidPeso molecular:381.51SERT-IN-2
SERT-IN-2, a potent SERT inhibitor (IC 50 = 0.58 nM), exhibits promising efficacy as an anti-depressant.Cor e Forma:SolidNAP-1
CAS:<p>NAP-1 is an anesthetic that enhances CA1 brain inhibition in rats and causes tadpole sedation (EC50 = 0.53 μM).</p>Fórmula:C20H18ClNO2Cor e Forma:SolidPeso molecular:339.82RU-505
CAS:RU-505 is an interaction inhibitor of Aβ-fibrinogen that acts by rescuing altered thrombosis and cognitive decline in Alzheimer's disease mice.Fórmula:C28H32FN5OPureza:98%Cor e Forma:SolidPeso molecular:473.58FG-5893
CAS:FG-5893 is a 5-HT1A agonist and 5-HT2 antagonist with potential anxiolytic activity.Fórmula:C27H29F2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:465.53BACE2-IN-1
CAS:<p>BACE2-IN-1, a potent BACE2 inhibitor characterized by its exceptional selectivity and a Ki value of 1.6 nM, is utilized in the investigation of Type 2 Diabetes.</p>Fórmula:C36H38F3N3O3Cor e Forma:SolidPeso molecular:617.7LSP4-2022
CAS:LSP4-2022, a mGlu4 selective agonist, increases behavioral despair in mouse models of antidepressant action.Fórmula:C13H18NO8PPureza:100%Cor e Forma:SolidPeso molecular:347.26AChE/BuChE-IN-2
CAS:Compound 5f, an oral AChE/BuChE inhibitor, crosses BBB; IC50: 0.72 μM (AChE), 0.16 μM (BuChE), 62.52 μM (Aβ aggregation).Fórmula:C20H18N2O2Cor e Forma:SolidPeso molecular:318.37Trimedoxime bromide
CAS:Trimedoxime bromide is a cholinesterase reactivator used as an antidote in alkyl phosphate poisoning.Fórmula:C15H18Br2N4O2Cor e Forma:SolidPeso molecular:446.14Lidanserin
CAS:Lidanserin is an antagonist of the 5-HT2A and α1-adrenergic receptor.Fórmula:C26H31FN2O4Pureza:98%Cor e Forma:SolidPeso molecular:454.53
