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Neurociência

Neurociência

Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.

Subcategorias de "Neurociência"

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Foram encontrados 5389 produtos de "Neurociência"

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  • CPPHA

    CAS:
    <p>CPPHA, a positive allosteric modulator of glutamate receptors mGluR5 and mGluR1, is commonly used in development for central nervous system diseases.</p>
    Fórmula:C22H15ClN2O4
    Pureza:98.07%
    Cor e Forma:Solid
    Peso molecular:406.82
  • Ethybenztropine

    CAS:
    <p>Ethybenztropine is an anticholinergic used as an antiparkinsonian agent and may also act as a dopamine reuptake inhibitor.</p>
    Fórmula:C22H27NO
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:321.46
  • Zicronapine

    CAS:
    <p>Zicronapine (LU 31-130), an atypical antipsychotic with monoaminergic action, targets dopamine D1/D2 and serotonin 5HT2A.</p>
    Fórmula:C22H27ClN2
    Cor e Forma:Solid
    Peso molecular:354.92
  • 5-HT7 agonist 2

    CAS:
    <p>Potent 5-HT7 agonist with 28.7 nM IC50; promising for CNS disorder research.</p>
    Fórmula:C23H29N3O
    Cor e Forma:Solid
    Peso molecular:363.5
  • ML375

    CAS:
    <p>ML375 is a potent, selective and CNS penetrant M5 negative allosteric modulator (NAM).</p>
    Fórmula:C23H15ClF2N2O2
    Cor e Forma:Solid
    Peso molecular:424.83
  • Memoquin

    CAS:
    <p>Memoquin is a multi-target-directed ligand for the therapy of Alzheimer's disease.</p>
    Fórmula:C38H56N4O4
    Cor e Forma:Solid
    Peso molecular:632.88
  • T 82

    CAS:
    <p>T 82 is an antagonist of 5-HT3 and inhibitor of acetylcholinesterase (AChE) and used for the treatment of Alzheimer's Disease.</p>
    Fórmula:C56H62N6O8
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:947.146
  • CGP 36216 hydrochloride

    CAS:
    <p>CGP 36216 hydrochloride is a potent and selective antagonist of GABAB receptors (IC50: 43 μM).</p>
    Fórmula:C5H14NO2P
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:151.14
  • β-CCB

    CAS:
    <p>benzodiazepine receptor ligand</p>
    Fórmula:C16H16N2O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:268.31
  • IEM 1925 dihydrobromide

    CAS:
    <p>AMPA receptor antagonist</p>
    Fórmula:C17H30Br2N2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:422.24
  • Bibn 99

    CAS:
    <p>Bibn 99, a lipophilic and selective muscarinic M2 receptor antagonist, has applications in cognitive performance and Alzheimer's Disease.</p>
    Fórmula:C31H42ClN5O3
    Cor e Forma:Solid
    Peso molecular:568.15
  • BChE-IN-7

    CAS:
    <p>BChE-IN-7 inhibits AChE/BChE selectively and reversibly; IC50 for BChE: 0.06 μM; crosses blood-brain barrier, protects neurons from Aβ toxicity.</p>
    Fórmula:C21H24N2O2
    Cor e Forma:Solid
    Peso molecular:336.43
  • Ambutonium bromide

    CAS:
    <p>Ambutonium bromide is an antagonist of acetylcholine.</p>
    Fórmula:C20H27BrN2O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:391.35
  • Caroxazone

    CAS:
    <p>Caroxazone is an antidepressant drug, monoamine oxidase inhibitor (MAOI) that is irreversible and nonselective meanwhile.</p>
    Fórmula:C10H10N2O3
    Cor e Forma:Solid
    Peso molecular:206.2
  • Dizocilpine

    CAS:
    <p>MK-801 (Dizocilpine (MK-801)) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM.</p>
    Fórmula:C16H15N
    Pureza:99.85% - 99.97%
    Cor e Forma:Solid
    Peso molecular:221.3
  • GR 113808

    CAS:
    <p>GR 113808 is a 5-HT4 receptor antagonist that inhibits 5-HT1B and 5-HT3 receptors and attenuates morphine-stimulated dopamine release in the rat striatum.</p>
    Fórmula:C19H27N3O4S
    Pureza:98.16%
    Cor e Forma:Solid
    Peso molecular:393.5
  • Foliglurax

    CAS:
    Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) (EC50: 79 nM).
    Fórmula:C23H23N3O3S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:421.51
  • CPP-115

    CAS:
    <p>CPP-115 is a GABA-aminotransferase inhibitor and a high-affinity vigabatrin analogue.</p>
    Fórmula:C7H9F2NO2
    Cor e Forma:Solid
    Peso molecular:177.15
  • NPEC-caged-LY379268

    CAS:
    <p>NPEC-caged-LY379268 is a type II mGluR agonist [1].</p>
    Fórmula:C16H16N2O9
    Cor e Forma:Solid
    Peso molecular:380.31
  • MDL 73005EF hydrochloride

    CAS:
    5-HT1A receptor antagonist
    Fórmula:C20H27ClN2O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:394.89
  • sEH inhibitor-5

    CAS:
    <p>sEH inhibitor-5 is a potent inhibitor of sEH (soluble epoxide hydrolase) (IC50: 0.1 nM).</p>
    Fórmula:C27H26Cl2N6O3S
    Cor e Forma:Solid
    Peso molecular:585.5
  • LY 302148

    CAS:
    <p>LY 302148 , a 5-HT1F receptor agonist, inhibits neurogenic dural inflammation in guinea pigs. It has potential for migraine therapeutics.</p>
    Fórmula:C19H23FN4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:326.41
  • VU0155041 sodium

    CAS:
    VU0155041 sodium is a positive allosteric modulator of mGluR4 that promotes extinction in male rats.
    Fórmula:C14H14Cl2NNaO3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:338.16
  • Bornaprine

    CAS:
    <p>Bornaprine is an anticholinergic drug used to treat Parkinson's disease due to inhibition of muscarinic or nicotinic transmission.</p>
    Fórmula:C21H31NO2
    Cor e Forma:Solid
    Peso molecular:329.48
  • Yhhu-3792

    CAS:
    <p>Yhhu-3792 activates Notch, boosts Hes3/Hes5, enhances NSC renewal, expands NSC pool, and may improve memory.</p>
    Fórmula:C24H24N4O2
    Cor e Forma:Solid
    Peso molecular:400.47
  • Indisetron Dihydrochloride

    CAS:
    <p>Indisetron Dihydrochloride is a 5-HT(3) and 5-HT(4) receptor antagonist. Indisetron reduces 2-methyl-5-serotonin (HT)-induced bradycardia.</p>
    Fórmula:C17H24ClN5O
    Cor e Forma:Solid
    Peso molecular:349.86
  • Btm 1042

    CAS:
    <p>Btm 1042 is an antispasmodic drug. It has been found to depress twitch responses in the ileum of guinea pigs.</p>
    Fórmula:C21H26ClN3OS
    Cor e Forma:Solid
    Peso molecular:403.97
  • E-3620

    CAS:
    E-3620 is a potent antagonist of the 5-HT3 receptor and can be used to study dyskinesia and gastrointestinal dysfunction.
    Fórmula:C20H27Cl2N3O2
    Pureza:98.88% - 98.88%
    Cor e Forma:Solid
    Peso molecular:412.35
  • GABAA receptor agent 7

    CAS:
    <p>Compound 5c, a GABAA receptor modulator with anticonvulsant properties and low neurotoxicity, is promising for epilepsy research.</p>
    Fórmula:C18H13ClN4O
    Cor e Forma:Solid
    Peso molecular:336.77
  • M1 ligand 1

    CAS:
    <p>Compound 3b-b: N-desmethyl arecoline derivative, muscarinic M1 ligand, potential PET radiotracer.</p>
    Fórmula:C20H21NO2
    Cor e Forma:Solid
    Peso molecular:307.39
  • sEH/AChE-IN-1

    CAS:
    <p>Compound 12a is a dual sEH/AChE inhibitor with potential for treating Alzheimer's-related neuroinflammation and memory loss.</p>
    Fórmula:C29H31ClF3N5O3
    Cor e Forma:Solid
    Peso molecular:590.04
  • SDZ 205-557 hydrochloride

    CAS:
    <p>5-HT3/5-HT4 receptor antagonist</p>
    Fórmula:C14H22Cl2N2O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:337.24
  • YM 114

    CAS:
    <p>YM 114 is an anatagonist of 5-HT(3) receptor.</p>
    Fórmula:C16H18ClN3O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:303.79
  • AChE/BChE/MAO-B-IN-2


    <p>AChE/BChE/MAO-B-IN-2 inhibits AChE (48.2 nM), BChE (83.9 nM), MAO-B (31.2 nM), has antioxidant activity, and aids Parkinson's research.</p>
    Fórmula:C25H31N3O3
    Cor e Forma:Solid
    Peso molecular:421.53
  • MMPIP

    CAS:
    <p>allosteric mGlu7-selective receptor antagonist</p>
    Fórmula:C19H15N3O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:333.34
  • MFZ 10-7 hydrochloride

    CAS:
    MFZ 10-7 hydrochloride is a highly potent and selective negative allosteric modulator of mGluR5 NAM
    Fórmula:C15H10ClFN2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:272.71
  • UMB68 sodium

    CAS:
    <p>UMB-68 is a GHB receptor ligand with no affinity (IC(50) &gt;100 microM) at GABA(A) or GABA(B) receptors.</p>
    Fórmula:C6H12NaO3
    Cor e Forma:Solid
    Peso molecular:155.149
  • RU-505

    CAS:
    <p>RU-505 is an interaction inhibitor of Aβ-fibrinogen that acts by rescuing altered thrombosis and cognitive decline in Alzheimer's disease mice.</p>
    Fórmula:C28H32FN5O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:473.58
  • PD-102807

    CAS:
    <p>PD-102807 is a selective and competitive M4 muscarinic receptor antagonist for Parkinson's disease research, inhibit airway smooth muscle (ASM) contraction.</p>
    Fórmula:C23H24N2O4
    Pureza:98.90%
    Cor e Forma:Solid
    Peso molecular:392.45
  • Palonosetron

    CAS:
    <p>Palonosetron, a 5-HT3 antagonist with Ki of 0.17 nM, is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).</p>
    Fórmula:C19H24N2O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:296.41
  • MK-0343

    CAS:
    <p>MK0343 is an orally bioavailable GABAA receptor subtype-selective partial agonist and is a non-sedating anxiolytic.</p>
    Fórmula:C19H17F2N7O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:397.38
  • AF-DX 384 free base

    CAS:
    <p>AF-DX 384 free base is an M2 mAChR and M4 mAChR antagonist, useful in research on neurodivisions and diseases such as Parkinson's.</p>
    Fórmula:C27H38N6O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:478.63
  • E2730

    CAS:
    <p>E2730 is a non-competitive GABA transporter 1 (GAT1) inhibitor with anti-epileptic activity, useful in studying neurological disorders.</p>
    Fórmula:C9H8F4N2O2S
    Pureza:98.22% - 98.54%
    Cor e Forma:Solid
    Peso molecular:284.23
  • MAO-B-IN-21

    CAS:
    <p>MAO-B-IN-21: MAO-B inhibitor with antioxidant, anti-amyloid aggregation, neuroprotective properties, BBB permeable, improves memory in Alzheimer's mice.</p>
    Fórmula:C24H25ClN2O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:440.92
  • (S)-SNAP5114

    CAS:
    <p>(S)-SNAP5114 is a selective inhibitor of GABA transport with IC50s of 5 μM for hGAT-3 and 21 μM for rGAT-2. (S)-SNAP5114 has anticonvulsant properties.</p>
    Fórmula:C30H35NO6
    Pureza:97%
    Cor e Forma:Solid
    Peso molecular:505.6
  • CJ 033466

    CAS:
    <p>CJ 033466 is a selective partial agonist of 5-HT4 receptor (EC50 = 9 nM) with gastroprokinetic effect.</p>
    Fórmula:C19H28ClN5O
    Pureza:99.72%
    Cor e Forma:Solid
    Peso molecular:377.91
  • Quifenadine

    CAS:
    <p>Quifenadine, an H1-histamine receptor blocker, has antiarrhythmic properties.</p>
    Fórmula:C20H23NO
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:293.4
  • Mirisetron

    CAS:
    <p>Mirisetron (WAY-100579, SEC-579) is a 5-HT3 receptor antagonist, cognitive-enhancing effects. counteracts learning deficits.</p>
    Fórmula:C24H31N3O2
    Pureza:99.88%
    Cor e Forma:Solid
    Peso molecular:393.52
  • Nitroflurbiprofen

    CAS:
    <p>Nitroflurbiprofen (Nitroxybutyl flurbiprofen) is a NO-releasing COX inhibitor and modulates the increased intrahepatic vascular tone in portal hypertensive</p>
    Fórmula:C19H20FNO5
    Pureza:99.88%
    Cor e Forma:Solid
    Peso molecular:361.36
  • (RS)-4-Carboxy-3-hydroxyphenylglycine

    CAS:
    <p>broad spectrum EAA agonist/antagonist</p>
    Fórmula:C9H9NO5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:211.17