Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(942 produtos)
- ACK(1 produtos)
- AChR(575 produtos)
- ATP Citrato Liase(16 produtos)
- Receptor adrenérgico(2.948 produtos)
- BACE(36 produtos)
- Beta Amilóide(205 produtos)
- CaMK(69 produtos)
- COX(565 produtos)
- Receptor de Dopamina(409 produtos)
- Receptor GABA(336 produtos)
- Gama-secretase(59 produtos)
- GluR(255 produtos)
- GlyT(24 produtos)
- Receptor de Histamina(359 produtos)
- LRRK2(33 produtos)
- Receptor de Melatonina(24 produtos)
- NMDAR(27 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5390 produtos de "Neurociência"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
sEH/AChE-IN-2
CAS:<p>sEH/AChE-IN-2 targets sEH & AChE, may reduce neuroinflammation & memory loss, potential in Alzheimer's research.</p>Fórmula:C30H33ClF3N5O3Cor e Forma:SolidPeso molecular:604.06W-13 hydrochloride
CAS:<p>W-13 hydrochloride (W-13 HCl) is a calmodulin antagonist.</p>Fórmula:C14H18Cl2N2O2SPureza:98.51%Cor e Forma:White PowderPeso molecular:349.28Eplivanserin
CAS:<p>Eplivanserin (SR-46349) is an effective and selective antagonist of 5-HT2A receptor with a Kd of 1.14 nM and an IC50 value of 5.8 nM in rat cortical membrane.</p>Fórmula:C19H21FN2O2Pureza:97.04%Cor e Forma:SolidPeso molecular:328.38PGP-4008
CAS:<p>PGP-4008 is a selective and potent P-glycoprotein (Pgp) inhibitor that inhibits tumor growth by co-administration with Doxorubicin.</p>Fórmula:C26H23N3OPureza:98.07% - 98.95%Cor e Forma:SolidPeso molecular:393.48CP94253 hydrochloride
CAS:<p>CP94253 hydrochloride: selective 5-HT1B agonist, Ki=2 nM; less active on 5-HT1A/D/C/2 (Ki=89/49/860/1600 nM).</p>Fórmula:C15H20ClN3OPureza:99.78%Cor e Forma:SolidPeso molecular:293.79(R)-Baclofen hydrochloride
CAS:<p>Arbaclofen HCl, a GABA-B agonist, treats spasticity from spinal injury by reducing excitatory transmission.</p>Fórmula:C10H13Cl2NO2Pureza:98%Cor e Forma:SolidPeso molecular:250.12Enciprazine
CAS:<p>Enciprazine (D-3112) shows anxiolytic activity, is used to treat anxiety disorders, and can be used to study depression.</p>Fórmula:C23H32N2O6Pureza:98.63%Cor e Forma:SolidPeso molecular:432.51Org-13011 fumarate
CAS:<p>Org-13011 fumarate1 is an agonist of the 5-HT1A receptor and can be used to study neurological disorders.</p>Fórmula:C22H29F3N4O5Pureza:98.92%Cor e Forma:SolidPeso molecular:486.48LP44 hydrochloride
CAS:<p>LP44 hydrochloride is a 5-HT7 agonist with analgesic effects on formalin-induced orofacial pain in mice and can be used to study neuroinflammation.</p>Fórmula:C27H38ClN3OSPureza:98.06%Cor e Forma:SolidPeso molecular:488.13LY 334370 hydrochloride
CAS:5-HT1F receptor agonistFórmula:C21H23ClFN3OPureza:98%Cor e Forma:SolidPeso molecular:387.88Lesogaberan
CAS:<p>Lesogaberan: selective GABAB agonist, EC50 8.6 nM, Ki 5.1 nM in rats, weak GABAA affinity (Ki 1.4 μM).</p>Fórmula:C3H9FNO2PPureza:98%Cor e Forma:SolidPeso molecular:141.08BChE-IN-7
CAS:<p>BChE-IN-7 inhibits AChE/BChE selectively and reversibly; IC50 for BChE: 0.06 μM; crosses blood-brain barrier, protects neurons from Aβ toxicity.</p>Fórmula:C21H24N2O2Cor e Forma:SolidPeso molecular:336.43Tracazolate hydrochloride
CAS:<p>Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity.</p>Fórmula:C16H25ClN4O2Pureza:99.52%Cor e Forma:SolidPeso molecular:340.85BuChE-IN-6
CAS:<p>BuChE-IN-6 inhibits BuChE (IC50: 0.46 μM eqBuChE, 0.51 μM hBuChE) and prevents Aβ 42 self-aggregation.</p>Fórmula:C21H26N4O2Cor e Forma:SolidPeso molecular:366.46Phenoxypropazine
CAS:<p>Phenoxypropazine, a potent monoamine oxidase (MAO) inhibitor, is utilized in depression research.</p>Fórmula:C9H14N2OCor e Forma:SolidPeso molecular:166.22GR 113808
CAS:<p>GR 113808 is a 5-HT4 receptor antagonist that inhibits 5-HT1B and 5-HT3 receptors and attenuates morphine-stimulated dopamine release in the rat striatum.</p>Fórmula:C19H27N3O4SPureza:98.16%Cor e Forma:SolidPeso molecular:393.5Foliglurax
CAS:<p>Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) (EC50: 79 nM).</p>Fórmula:C23H23N3O3SPureza:98%Cor e Forma:SolidPeso molecular:421.51Ziprasidone mesylate trihydrate
CAS:<p>Ziprasidone mesylate hydrate is an oral 5-HT/D2 antagonist with Ki: D2=4.8nM, 5-HT2A=0.42nM, 5-HT1A=3.4nM in rats.</p>Fórmula:C22H31ClN4O7S2Cor e Forma:SolidPeso molecular:563.08SSAO inhibitor-3
CAS:<p>SSAO inhibitor-3 targets human AOC1/SSAO in atherosclerosis, diabetes, obesity, CKD, and more, with IC50s of 0.1-10 μM/<10 nM.</p>Fórmula:C15H23FN4O3Cor e Forma:SolidPeso molecular:326.37VU0652835
CAS:<p>VU0652835 is a negative allosteric modulator of metabotropic glutamate receptor subtype 5 (mGlu5) (IC50: 81 nM).</p>Fórmula:C16H19N3O3SPureza:98%Cor e Forma:SolidPeso molecular:333.41Quifenadine
CAS:<p>Quifenadine, an H1-histamine receptor blocker, has antiarrhythmic properties.</p>Fórmula:C20H23NOPureza:98%Cor e Forma:SolidPeso molecular:293.4Naronapride
CAS:<p>Naronapride (ATI-7505) is a potent agonist of the prokinetic 5-HT4receptor and can be used to study gastrointestinal disorders.</p>Fórmula:C27H41ClN4O5Cor e Forma:SolidPeso molecular:537.09Deramciclane
CAS:Deramciclane has high affinity for 5-HT2A and 5-HT2C receptors.Fórmula:C20H31NOCor e Forma:SolidPeso molecular:301.47JI051
CAS:JI051 has anti-tumor effects and can interact with PHB2 to inhibit the proliferation of HEK293 cells and pancreatic cancer cells.Fórmula:C22H24N2O3Pureza:≥98% - ≥98.0%Cor e Forma:SolidPeso molecular:364.44RU-505
CAS:<p>RU-505 is an interaction inhibitor of Aβ-fibrinogen that acts by rescuing altered thrombosis and cognitive decline in Alzheimer's disease mice.</p>Fórmula:C28H32FN5OPureza:98%Cor e Forma:SolidPeso molecular:473.58A-794282
CAS:<p>A-794282 is a selective antagonist of mGluR1.</p>Fórmula:C19H18N4OSPureza:99.87%Cor e Forma:SolidPeso molecular:350.44ML381
CAS:<p>ML381 is a M5-orthosteric antagonist with a high selectivity of muscarinic subtype.</p>Fórmula:C21H21N3O4Cor e Forma:SolidPeso molecular:379.41(RS)-PPG
CAS:<p>(RS)-PPG: Potent, selective III mGluRs agonist; EC50s: hmGluR4a 5.2μM, hmGluR6 4.7μM, hmGluR7b 185μM, hmGluR8a 0.2μM; neuroprotective, anticonvulsive.</p>Fórmula:C8H10NO5PPureza:98%Cor e Forma:SolidPeso molecular:231.14GR 196429
CAS:<p>GR 196429: MT1-selective melatonin receptor agonist; induces sleep, alters circadian rhythm, stimulates melatonin in mice.</p>Fórmula:C14H18N2O2Pureza:98%Cor e Forma:SolidPeso molecular:246.3HTL14242
CAS:<p>HTL14242 is a mGlu5 Negative Allosteric Modulator.</p>Fórmula:C16H8ClFN4Cor e Forma:SolidPeso molecular:310.71BACE-IN-1
CAS:<p>BACE-IN-1 is an imidazo[1,2-a]pyridine derivative that inhibits the β-site amyloid precursor protein cleavage enzyme (BACE) sentence.BACE-IN-1 has the potential</p>Fórmula:C22H16ClN5O2Pureza:98%Cor e Forma:SolidPeso molecular:417.85BChE-IN-8
CAS:<p>BChE-IN-8, compound 20, is a potent oral BChE inhibitor effective on eqBChE and hBChE, crosses blood-brain barrier, and may help in Alzheimer's research.</p>Fórmula:C18H12BrN7O2Cor e Forma:SolidPeso molecular:438.24γ-Secretase modulator 4
CAS:<p>γ-Secretase modulator 4 is a potent γ-secretase modulator, reduces the Aβ42 level with IC50s of 0.017 μM and 0.014 μM in mouse and human, respectively.</p>Fórmula:C23H19FN4O2Pureza:98%Cor e Forma:SolidPeso molecular:402.42Ro 04-6790
CAS:<p>Ro 04-6790 is a 5-HT6 receptor antagonist.</p>Fórmula:C12H16N6O2SPureza:98%Cor e Forma:SolidPeso molecular:308.36PNU-107484A
CAS:<p>PNU-107484A is a unique GABA(A) receptor ligand.</p>Fórmula:C18H23ClN6Pureza:98%Cor e Forma:SolidPeso molecular:358.87(S)-3,5-DHPG
CAS:<p>group I mGlu receptor agonist</p>Fórmula:C8H9NO4Pureza:98%Cor e Forma:SolidPeso molecular:183.16Alniditan dihydrochloride
CAS:<p>Alniditan dihydrochloride is a potent 5-HT1D agonist and migraine-abortive agent.</p>Fórmula:C17H28Cl2N4OCor e Forma:SolidPeso molecular:375.34SB 272183
CAS:<p>SB 272183 is a highly potent dual 5-HT1A and 5-HT1B antagonists as potential antidepressant drug.</p>Fórmula:C29H28ClN5OPureza:98%Cor e Forma:SolidPeso molecular:498.02SUN-C5174
CAS:<p>"SUN-C5174 is a selective 5-HT2 antagonist with pA2=8.98; inhibits platelet aggregation and reduces thromboembolic death in mice at ≥0.3 mg/kg."</p>Fórmula:C22H29FN4O2Pureza:98%Cor e Forma:SolidPeso molecular:400.49GABAA receptor agent 8
CAS:<p>Compound 5e, a GABAA receptor modulator, shows potent anticonvulsant effects with low neurotoxicity for epilepsy research.</p>Fórmula:C19H16N4OCor e Forma:SolidPeso molecular:316.36JN403
CAS:<p>JN403 is a selective agonist of nicotinic acetylcholine receptor alpha7.</p>Fórmula:C16H21FN2O2Cor e Forma:SolidPeso molecular:292.35(S)-3-Carboxy-4-hydroxyphenylglycine
CAS:<p>group I metabotropic glutamate receptor antagonist and group II mGlu agonist</p>Fórmula:C9H9NO5Pureza:98%Cor e Forma:SolidPeso molecular:211.17Tertatolol
CAS:<p>Tertatolol is an effective antagonist of beta-adrenoceptor and 5-HT receptors.</p>Fórmula:C16H25NO2SPureza:98%Cor e Forma:SolidPeso molecular:295.44DAA-1097
CAS:<p>DAA-1097 is a novel ligand of peripheral benzodiazepine receptor.</p>Fórmula:C24H24ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:409.91HIE-124
CAS:<p>HIE-124 is a central cervous system active anticonvulsant and ultra-short acting hypnotic.</p>Fórmula:C10H12N2O3SPureza:98%Cor e Forma:SolidPeso molecular:240.28ABP-700
CAS:<p>ABP-700 is a positive allosteric modulator of the GABAA receptor.</p>Fórmula:C17H18N2O4Pureza:98%Cor e Forma:SolidPeso molecular:314.34Suclofenide
CAS:<p>Suclofenide: a benzenesulfonamide anticonvulsant, effective in mouse seizure models, with side effects like lethargy and diarrhea.</p>Fórmula:C16H13ClN2O4SPureza:98%Cor e Forma:SolidPeso molecular:364.8RS-0466
CAS:<p>RS-0466 is an β-amyloid-induced cytotoxicity inhibitor.</p>Fórmula:C17H17N5O2Pureza:98%Cor e Forma:SolidPeso molecular:323.35Fluoroclorgyline
CAS:Fluoroclorgyline is a specific inhibitor of monoamine oxidase A (MAO-A).Fórmula:C13H15ClFNOPureza:98%Cor e Forma:SolidPeso molecular:255.72Aganodine
CAS:<p>Aganodine, a guanidine, activates imidazoline receptors to inhibit norepinephrine release.</p>Fórmula:C9H10Cl2N4Pureza:98%Cor e Forma:SolidPeso molecular:245.11
