Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(942 produtos)
- ACK(1 produtos)
- AChR(575 produtos)
- ATP Citrato Liase(16 produtos)
- Receptor adrenérgico(2.948 produtos)
- BACE(36 produtos)
- Beta Amilóide(205 produtos)
- CaMK(69 produtos)
- COX(565 produtos)
- Receptor de Dopamina(409 produtos)
- Receptor GABA(336 produtos)
- Gama-secretase(59 produtos)
- GluR(255 produtos)
- GlyT(24 produtos)
- Receptor de Histamina(359 produtos)
- LRRK2(33 produtos)
- Receptor de Melatonina(24 produtos)
- NMDAR(27 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5390 produtos de "Neurociência"
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PF-3246799
CAS:<p>PF-3246799 is an effective and selective agonist of the 5-HT2C receptor.</p>Fórmula:C15H17N3Pureza:98%Cor e Forma:SolidPeso molecular:239.32Protriptyline
CAS:<p>Protriptyline: Antidepressant, AChE inhibitor (IC50 0.06 mM), prevents Aβ aggregation; potential for depression and Alzheimer's.</p>Fórmula:C19H21NCor e Forma:SolidPeso molecular:263.38TMPPAA
CAS:<p>TMPPAA is an allosteric agonist of 5-HT3 receptor.</p>Fórmula:C15H21NO2Pureza:98%Cor e Forma:SolidPeso molecular:247.33CGP 46381
CAS:<p>CGP 46381 is a GABAB receptor antagonist.</p>Fórmula:C10H22NO2PPureza:98%Cor e Forma:White SolidPeso molecular:219.26Sofiniclin
CAS:<p>Sofiniclin (ABT 894) is an agonist of nicotinic acetylcholine receptor (nAChR). It is used for the research for attention-deficit/hyperactivity disorder (ADHD).</p>Fórmula:C10H11Cl2N3Pureza:98%Cor e Forma:SolidPeso molecular:244.12ONT-093
CAS:<p>ONT-093 (OC-144-093) is an oral P-glycoprotein (P-gp) inhibitor with potential anti-cancer activity, used in the study of myelodysplastic syndromes.</p>Fórmula:C32H38N4OPureza:98.86%Cor e Forma:SolidPeso molecular:494.67ML337
CAS:ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.Fórmula:C21H20FNO3Pureza:99.83%Cor e Forma:SolidPeso molecular:353.39(+)-Donepezil
CAS:<p>(+)-Donepezil is an isomer of Donepezil -- a nootropic acting as an inhibitor of acetylcholinesterase.</p>Fórmula:C24H29NO3Cor e Forma:SolidPeso molecular:379.49LY 302148
CAS:<p>LY 302148 , a 5-HT1F receptor agonist, inhibits neurogenic dural inflammation in guinea pigs. It has potential for migraine therapeutics.</p>Fórmula:C19H23FN4Pureza:98%Cor e Forma:SolidPeso molecular:326.41SV5
CAS:<p>SV5: potent anti-Alzheimer's, protects SHSY-5Y from Aβ1-42 death, stable with optimal pharmacology in plasma, antioxidant, neuroprotective.</p>Fórmula:C21H30N2O4S2Cor e Forma:SolidPeso molecular:438.6GR 196429
CAS:<p>GR 196429: MT1-selective melatonin receptor agonist; induces sleep, alters circadian rhythm, stimulates melatonin in mice.</p>Fórmula:C14H18N2O2Pureza:98%Cor e Forma:SolidPeso molecular:246.3CP-409092 hydrochloride
CAS:<p>CP-409092 hydrochloride is a partial agonist of the GABAA receptor with anti-anxiety activity.</p>Fórmula:C17H20ClN3O2Cor e Forma:SolidPeso molecular:333.81J-104129 fumarate
CAS:<p>J-104129 fumarate is a potent M3 muscarinic receptor antagonist.</p>Fórmula:C28H40N2O6Cor e Forma:SolidPeso molecular:500.63CK59
CAS:<p>CK59 inhibits CaMKII and several voltage-gated calcium channels, with an IC50 of ~50 μM.</p>Fórmula:C21H37N7O3Pureza:98%Cor e Forma:SolidPeso molecular:435.56VU0364289
CAS:<p>VU0364289 is a positive allosteric modulator of mGlu5.</p>Fórmula:C20H21N3O2Cor e Forma:SolidPeso molecular:335.4Revatropate
CAS:<p>Revatropate, a selective muscarinic antagonist, is an antimuscarinic drug.</p>Fórmula:C19H27NO4SCor e Forma:SolidPeso molecular:365.49Y 23684
CAS:<p>Y-23684 is an anxiolytic drug with a novel chemical structure. It has similar effects to benzodiazepine drugs and is classed as a nonbenzodiazepine anxiolytic.</p>Fórmula:C18H13ClN2O2SPureza:98%Cor e Forma:SolidPeso molecular:356.83mGluR2 modulator 4
CAS:<p>Compound 47 is a potent mGluR2 enhancer with an EC50 of 0.8 μM, potentially useful for antipsychotic research.</p>Fórmula:C18H18BrN3Cor e Forma:SolidPeso molecular:356.26Cyprodenate
CAS:<p>Cyprodenate (Actebral) is a potent orally active brain-activating agent with appetite-suppressing properties, useful in studying metabolic.</p>Fórmula:C13H25NO2Cor e Forma:SolidPeso molecular:227.34Pralidoxime
CAS:<p>Pralidoxime reactivates AChE blocked by nerve agents, aiding as an organophosphate poisoning antidote.</p>Fórmula:C7H9N2OCor e Forma:SolidPeso molecular:137.16PXS-4787
CAS:<p>PXS-4787 selectively inhibits LOX with IC50 values: 2 μM (Bovine), 3.2 μM (LOXL1), 0.6 μM (LOXL2), 1.4 μM (LOXL3), 0.2 μM (LOXL4).</p>Fórmula:C10H12FNO2SCor e Forma:SolidPeso molecular:229.27Mebanazine
CAS:<p>Mebanazine, a potent monoamine oxidase (MAO) inhibitor, is utilized in depression research.</p>Fórmula:C8H12N2Cor e Forma:SolidPeso molecular:136.19DS1
CAS:<p>DS1 is a GABAA receptor agonist which can stimulate gonadotropin subunit gene expression in mouse.</p>Fórmula:C18H10Br2ClN3OSCor e Forma:SolidPeso molecular:511.62CPPHA
CAS:<p>CPPHA, a positive allosteric modulator of glutamate receptors mGluR5 and mGluR1, is commonly used in development for central nervous system diseases.</p>Fórmula:C22H15ClN2O4Pureza:98.07%Cor e Forma:SolidPeso molecular:406.825-HT7 receptor ligand 1
CAS:<p>Compound 5c: 5-HT7 receptor ligand, K i = 8 nM, not hepatotoxic, moderate CYP3A4/CYP2D6 interaction.</p>Fórmula:C21H23N7Cor e Forma:SolidPeso molecular:373.45NFPS
CAS:<p>NFPS exerts neuroprotection via glyR alpha1 subunit in the rat model of transient focal cerebral ischaemia and reperfusion.</p>Fórmula:C24H24FNO3Pureza:98%Cor e Forma:SolidPeso molecular:393.45Phenglutarimid
CAS:<p>Phenglutarimid is an anticholinergic. It is used as an antiparkinsonian agent.</p>Fórmula:C17H24N2O2Pureza:98%Cor e Forma:SolidPeso molecular:288.38sEH/AChE-IN-1
CAS:<p>Compound 12a is a dual sEH/AChE inhibitor with potential for treating Alzheimer's-related neuroinflammation and memory loss.</p>Fórmula:C29H31ClF3N5O3Cor e Forma:SolidPeso molecular:590.04(RS)-4-Carboxy-3-hydroxyphenylglycine
CAS:<p>broad spectrum EAA agonist/antagonist</p>Fórmula:C9H9NO5Pureza:98%Cor e Forma:SolidPeso molecular:211.17Donitriptan
CAS:<p>Donitriptan 是一种 5-HT 受体激动剂，对 5-HT1B 和 5-HT1D 的 pKi 分别为 9.4 和 9.3。</p>Fórmula:C23H25N5O2Pureza:98.76%Cor e Forma:SolidPeso molecular:403.48LRE1
CAS:<p>LRE1 is a specific and allosteric soluble adenylyl cyclase inhibitor.</p>Fórmula:C12H13ClN4SPureza:>99.99%Cor e Forma:SolidPeso molecular:280.78JNJ1930942
CAS:<p>JNJ1930942 is a novel positive allosteric modulator of the α7 nicotinic acetylcholine receptor.</p>Fórmula:C16H11F4N3OSCor e Forma:SolidPeso molecular:369.34CP-601932
CAS:<p>CP-601932 (free base) is a selective base α( 4) β( 2) Nicotinic acetylcholine receptor agonist.</p>Fórmula:C12H12F3NCor e Forma:SolidPeso molecular:227.235-HT6/5-HT2A receptor ligand-2
CAS:<p>Compound 42: brain-penetrant, dual 5-HT6/5-HT2A antagonist, Ki of 25 nM/32 nM, pro-cognitive.</p>Fórmula:C20H18FN3O2Cor e Forma:SolidPeso molecular:351.37DR4485 hydrochloride
CAS:<p>5-HT7 antagonist</p>Fórmula:C26H29Cl3N2OPureza:98%Cor e Forma:SolidPeso molecular:491.88(±)-Duloxetine hydrochloride
CAS:<p>(±)-Duloxetine ((Rac)-Duloxetine) hydrochloride is the Duloxetine hydrochloride racemate.</p>Fórmula:C18H20ClNOSCor e Forma:SolidPeso molecular:333.88Ambenonium chloride tetrahydrate
CAS:<p>Ambenonium chloride, a salt with cholinesterase inhibiting properties, treats myasthenia gravis by enhancing acetylcholine activity.</p>Fórmula:C28H50Cl4N4O6Cor e Forma:SolidPeso molecular:680.53AChE/BChE/MAO-B-IN-2
<p>AChE/BChE/MAO-B-IN-2 inhibits AChE (48.2 nM), BChE (83.9 nM), MAO-B (31.2 nM), has antioxidant activity, and aids Parkinson's research.</p>Fórmula:C25H31N3O3Cor e Forma:SolidPeso molecular:421.53Ampreloxetine
CAS:<p>Ampreloxetine (TD-9855) is a norepinephrine reuptake inhibitor used to study neurological diseases.</p>Fórmula:C18H18F3NOPureza:98%Cor e Forma:SolidPeso molecular:321.34RG-12915
CAS:<p>RG-12915 is a selective antagonist of 5-HT3(IC50 value of 0.16 nM).</p>Fórmula:C20H25ClN2O2Pureza:98%Cor e Forma:SolidPeso molecular:360.88MMPIP
CAS:<p>allosteric mGlu7-selective receptor antagonist</p>Fórmula:C19H15N3O3Pureza:98%Cor e Forma:SolidPeso molecular:333.34T761-0184
CAS:<p>T761-0184 is a potent antagonist of α7 nicotinic receptor (nAChR) [1].</p>Fórmula:C16H20FN3OCor e Forma:SolidPeso molecular:289.35AP521
CAS:<p>AP521 is an agonist of the human 5-HT1A receptor (IC50: 94 nM).</p>Fórmula:C20H19ClN2O3SPureza:98%Cor e Forma:SolidPeso molecular:402.89WAY208466 dihydrochloride
CAS:<p>WAY208466 dihydrochloride is a 5-HT6 receptor agonist (EC50=7.3 nM) with antidepressant and anxiolytic activity.</p>Fórmula:C17H20Cl2FN3O2SPureza:98.43%Cor e Forma:SolidPeso molecular:420.33Clovoxamine
CAS:<p>Clovoxamine fumarate (DU 23811 fumarate) is a 5-HT reuptake, serotonin and norepinephrine inhibitor with antidepressant and anticonvulsant activity.</p>Fórmula:C14H21ClN2O2Pureza:99.44% - 99.75%Cor e Forma:SolidPeso molecular:284.78Lidanserin
CAS:<p>Lidanserin is an antagonist of the 5-HT2A and α1-adrenergic receptor.</p>Fórmula:C26H31FN2O4Pureza:98%Cor e Forma:SolidPeso molecular:454.53Trimedoxime bromide
CAS:<p>Trimedoxime bromide is a cholinesterase reactivator used as an antidote in alkyl phosphate poisoning.</p>Fórmula:C15H18Br2N4O2Cor e Forma:SolidPeso molecular:446.14GR 113808
CAS:<p>GR 113808 is a 5-HT4 receptor antagonist that inhibits 5-HT1B and 5-HT3 receptors and attenuates morphine-stimulated dopamine release in the rat striatum.</p>Fórmula:C19H27N3O4SPureza:98.16%Cor e Forma:SolidPeso molecular:393.5Foliglurax
CAS:<p>Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) (EC50: 79 nM).</p>Fórmula:C23H23N3O3SPureza:98%Cor e Forma:SolidPeso molecular:421.51Bifenazate
CAS:<p>Bifenazate is a positive allosteric modulator of GABA receptor. Bifenazate is an acaricide that controls 100% of mites at a concentration of 25 ppm.</p>Fórmula:C17H20N2O3Pureza:99.62%Cor e Forma:Solid CrystallinePeso molecular:300.35
