Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(647 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.027 produtos)
- BACE(37 produtos)
- Beta Amilóide(230 produtos)
- CaMK(73 produtos)
- COX(602 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(373 produtos)
- Gama-secretase(62 produtos)
- GluR(265 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(43 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(41 produtos)
- Receptor opioide(327 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5639 produtos de "Neurociência"
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hMAO-B-IN-6
CAS:Compound 17d (hMAO-B-IN-6) is an effective and selective hMAO-B inhibitor, demonstrating an IC 50 of 67.02 nM. It significantly ameliorates cognitive deficits induced by Scopolamine in Alzheimer's disease (AD) mice [1].Fórmula:C19H20N2O5Cor e Forma:SolidPeso molecular:356.37AChE/BChE-IN-9
CAS:Compound 7a inhibits AChE/BChE (IC50: 5.74/14.05 μM), has antioxidant effects (IC50: 57.35 μM), chelates iron, and affects amyloid β 1-42 aggregation.Fórmula:C20H19N3O4Cor e Forma:SolidPeso molecular:365.38LY 393558
CAS:Dual 5-HT1B/1D receptor antagonistFórmula:C26H31FN4O4S2Pureza:98%Cor e Forma:SolidPeso molecular:546.68AChE-IN-15
CAS:AChE-IN-15 is a reversible inhibitor of huAChE and huBChE (IC50: 6.8 μM, 16.1 μM), with antioxidant activity, used in Alzheimer's research.Fórmula:C23H24N2O7Cor e Forma:SolidPeso molecular:440.45CGP 7930
CAS:Positive allosteric modulator of GABAB receptorsFórmula:C19H32O2Pureza:98%Cor e Forma:SolidPeso molecular:292.46BuChE-IN-6
CAS:BuChE-IN-6 inhibits BuChE (IC50: 0.46 μM eqBuChE, 0.51 μM hBuChE) and prevents Aβ 42 self-aggregation.Fórmula:C21H26N4O2Cor e Forma:SolidPeso molecular:366.46AChE/BChE-IN-3
CAS:AChE/BChE-IN-3 (BMC-1) dual inhibitor: IC50 of 6.08 μM for elAChE, 0.383 μM for eqBChE.Fórmula:C15H24N2O3Cor e Forma:SolidPeso molecular:280.36Phenoxypropazine
CAS:Phenoxypropazine, a potent monoamine oxidase (MAO) inhibitor, is utilized in depression research.Fórmula:C9H14N2OCor e Forma:SolidPeso molecular:166.22SCH-50910 free base
CAS:SCH-50910 is an antagonist of GABAB receptor.Fórmula:C8H15NO3Cor e Forma:SolidPeso molecular:173.21Ziprasidone mesylate trihydrate
CAS:Ziprasidone mesylate hydrate is an oral 5-HT/D2 antagonist with Ki: D2=4.8nM, 5-HT2A=0.42nM, 5-HT1A=3.4nM in rats.Fórmula:C22H31ClN4O7S2Cor e Forma:SolidPeso molecular:563.08(-)-Donepezil
CAS:(-)-Donepezil is an isomer of Donepezil -- a nootropic acting as an inhibitor of acetylcholinesterase.Fórmula:C24H29NO3Cor e Forma:SolidPeso molecular:379.49SDZ 21009
CAS:β-adrenoceptor and 5-HT1A/1B receptor antagonistFórmula:C19H28N2O4Pureza:98%Cor e Forma:SolidPeso molecular:348.44Nexopamil racemate
CAS:Nexopamil racemate（(Rac)-Nexopamil） is a racemate of Nexopamil. The Nexopamil racemate has potential anti-asthmatic and anti-ulcer activity.Fórmula:C24H40N2O3Pureza:98.61%Cor e Forma:SolidPeso molecular:404.59PNU-96391
CAS:PNU-96391 (OSU-6162) is an antagonist of dopamine D2 and a partial agonist of 5-HT2A. PNU-96391 can be used in research on the treatment of chronic diseases.Fórmula:C15H23NO2SPureza:99.53%Cor e Forma:SolidPeso molecular:281.41Ref: TM-T28435
1mg73,00€1mL*10mM (DMSO)138,00€5mg146,00€10mg210,00€25mg319,00€50mg447,00€100mg600,00€200mg800,00€SSAO inhibitor-3
CAS:SSAO inhibitor-3 targets human AOC1/SSAO in atherosclerosis, diabetes, obesity, CKD, and more, with IC50s of 0.1-10 μM/<10 nM.Fórmula:C15H23FN4O3Cor e Forma:SolidPeso molecular:326.37SL-25.1188
CAS:SL-25.1188: Reversible MAO-B inhibitor with high brain uptake & slow plasma metabolism.Fórmula:C16H17F3N2O5Cor e Forma:SolidPeso molecular:374.31BuChE-IN-2
CAS:BuChE-IN-2 inhibits BuChE (IC50: 1.28 μM), NO (0.67 μM), Aβ, ROS, chelates Cu2+, penetrates BBB, used in Alzheimer's research.Fórmula:C28H20F4N6O3Cor e Forma:SolidPeso molecular:564.49Radequinil
CAS:Radequinil is a benzodiazepine receptor partial inverse agonist. Rade quinil binds to GABA(-) and GABA(+) ligand (Kis: 5.15 and 6.11 nM, respectively).Fórmula:C18H14N4O3Pureza:98%Cor e Forma:SolidPeso molecular:334.33Naronapride
CAS:Naronapride (ATI-7505) is a potent agonist of the prokinetic 5-HT4receptor and can be used to study gastrointestinal disorders.Fórmula:C27H41ClN4O5Cor e Forma:SolidPeso molecular:537.09(R)-Duloxetine Hydrochloride
CAS:(R)-Duloxetine Hydrochloride, naphthalenyloxy amine, binds human serum albumin, less effective than (S)-enantiomer as SNRI.Fórmula:C18H20ClNOSCor e Forma:SolidPeso molecular:333.87(S)-Rasagiline mesylate
CAS:(S)-Rasagiline mesylate is rasagiline S-isomer, and is an agent of anti-Parkinson.Fórmula:C13H17NO3SPureza:98%Cor e Forma:SolidPeso molecular:267.34BChE-IN-9
CAS:BChE-IN-9 (Azepano-11-deoxo-glycyrrhetol) is a hybrid BChE inhibitor (Ki: 0.21 μM).Fórmula:C30H51NOCor e Forma:SolidPeso molecular:441.73BTM-1086
CAS:BTM-1086 is a potent gastric secretory inhibitor and an anti-ulcer agent.Fórmula:C21H25N3OSPureza:98%Cor e Forma:SolidPeso molecular:367.51AP-521 (Free base)
CAS:AP-521, a 5-HT1A receptor antagonist, is used potentially for the treatment of anxiety.Fórmula:C20H18N2O3SCor e Forma:SolidPeso molecular:366.43Nelonicline citrate
CAS:Nelonicline citrate (ABT-126) is a selective α7 nAChR agonist with a Ki of 12.3 nM, studied for schizophrenia and Alzheimer's.Fórmula:C23H27N3O8SCor e Forma:SolidPeso molecular:505.54Glutaminyl Cyclase Inhibitor 5
Glutaminyl Cyclase Inhibitor 5 is a potent, selective inhibitor of human glutaminyl cyclase (hQC), demonstrating an inhibition concentration half-max (IC 50) ofFórmula:C22H30N6OCor e Forma:SolidPeso molecular:394.51TC299423
CAS:TC299423 is a novel agonist for nicotinic acetylcholine receptors (nAChRs). TC299423 modestly selectively targets α6β2 subtype.Fórmula:C11H15N3Cor e Forma:SolidPeso molecular:189.265-HT2A receptor agonist-2
CAS:Potent 5-HT2A receptor agonist-2 targets 5-HT2A/B/C with EC50 1.7, 0.58, 0.50 nM.Fórmula:C20H21ClN2O3Cor e Forma:SolidPeso molecular:372.85AVN-101 free base
CAS:AVN-101: potent 5-HT7 antagonist, also targets 5-HT6, 5-HT2A, 5-HT2C. Aims to treat CNS disorders.Fórmula:C21H24N2Cor e Forma:SolidPeso molecular:304.43RLH 033
CAS:RLH 033 is a selective ligand for the sigma 1 recognition site.Fórmula:C25H31ClN2O4Pureza:98%Cor e Forma:SolidPeso molecular:458.98TPA-023B
CAS:TPA-023B: oral GABAA α2/α3 agonist (Kis: 0.73/2 nM), α1 antagonist (Ki: 1.8 nM), non-sedating anxiolytic.Fórmula:C21H15F2N5OPureza:98%Cor e Forma:SolidPeso molecular:391.37J-104129 fumarate
CAS:J-104129 fumarate is a potent M3 muscarinic receptor antagonist.Fórmula:C28H40N2O6Cor e Forma:SolidPeso molecular:500.63mGluR2 modulator 4
CAS:Compound 47 is a potent mGluR2 enhancer with an EC50 of 0.8 μM, potentially useful for antipsychotic research.Fórmula:C18H18BrN3Cor e Forma:SolidPeso molecular:356.26SGC-AAK1-1N
CAS:SGC-AAK1-1N is a potent and selective inhibitor of AAK1 (AP2 associated kinase 1) with an IC 50 of 1.8 μM [1].Fórmula:C20H22N4O3SCor e Forma:SolidPeso molecular:398.482-PAT
CAS:2-PAT: reversible MAO-A inhib., IC50=0.721 µM; MAO-B inactivator, IC50=14.6 µM; potential in Parkinson's/depression study.Fórmula:C13H15NCor e Forma:SolidPeso molecular:185.26(S)-VQW-765
(S)-VQW-765, oral α7 nAChR partial agonist, may improve cognition in Alzheimer's and schizophrenia.Fórmula:C19H22N2OCor e Forma:SolidPeso molecular:294.39Ph-HTBA
CAS:Ph-HTBA: high-affinity CaMKIIα modulator, brain-penetrant, Kd 757 nM, used in ischemia/neurodegeneration research.Fórmula:C19H18O3Cor e Forma:SolidPeso molecular:294.34U-101017
CAS:U-101017 is a partial benzodiazepine receptor and GABAA receptor agonist.Fórmula:C23H27ClN4O3Pureza:98%Cor e Forma:SolidPeso molecular:442.94VU 0360172 hydrochloride
CAS:positive allosteric modulator of mGlu5 receptorsFórmula:C18H16ClFN2OPureza:98%Cor e Forma:SolidPeso molecular:330.78VU0463841
CAS:VU0463841 is a mGlu5 negative allosteric modulators.
Fórmula:C13H8ClFN4OCor e Forma:SolidPeso molecular:290.68Flupyrimin
CAS:Flupyrimin is the insect nicotinic acetylcholine receptor (nAChR) antagonist [1].Fórmula:C13H9ClF3N3OCor e Forma:SolidPeso molecular:315.68mCPBG
CAS:mCPBG is a potent high affinity agonist of 5-HT3 receptor.Fórmula:C8H10ClN5Cor e Forma:SolidPeso molecular:211.65BuChE-IN-7
BuChE-IN-7: selective hBuChe & eqBuChe inhibitor, IC50s 40/80 nM, boosts cognition & memory, and penetrates blood-brain barrier.Fórmula:C25H34N2O2Cor e Forma:SolidPeso molecular:394.55MAO-B-IN-14
CAS:MAO-B-IN-14 (Compound 9) is a potent and selective inhibitor of monoamine oxidase-B (MAO-B) with an IC 50 of 0.95 μM and a Ki of 0.55 μM for human MAO-B.Fórmula:C17H14O3SCor e Forma:SolidPeso molecular:298.36ZK93423
CAS:ZK93423: potent benzodiazepine agonist, IC50=1nM, non-selective, Ki=4.1-6nM for α1-α5 GABAA subunits.Fórmula:C23H22N2O4Cor e Forma:SolidPeso molecular:390.43CP 135807
CAS:CP 135807 is a 5-HT1D receptor agonist.Fórmula:C19H21N5O2Pureza:98%Cor e Forma:SolidPeso molecular:351.4Opiranserin
CAS:Opiranserin is a development as an injectable agent for the treatment of postoperative pain.Fórmula:C21H34N2O5Pureza:98%Cor e Forma:SolidPeso molecular:394.51VU6001966
CAS:VU6001966: potent, selective mGlu2 inhibitor (IC50=78 nM), negative modulator, with good CNS penetration.Fórmula:C17H15FN4O2Pureza:98%Cor e Forma:SolidPeso molecular:326.33Aβ Fibrillization modulator 1
CAS:Aβ Fibrillization Modulator 1 stabilizes amyloid-beta (Aβ) monomers, preventing their aggregation into fibrils.Fórmula:C17H12N4O3SSeCor e Forma:SolidPeso molecular:431.33
