Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(647 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.027 produtos)
- BACE(37 produtos)
- Beta Amilóide(230 produtos)
- CaMK(73 produtos)
- COX(602 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(373 produtos)
- Gama-secretase(62 produtos)
- GluR(265 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(43 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(41 produtos)
- Receptor opioide(327 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5639 produtos de "Neurociência"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Afacifenacin
CAS:Afacifenacin (SMP-986) fumarate is an M3-selective antagonist for ischemic heart disease and urinary disorders.Fórmula:C27H26F3N3O2Pureza:99.83%Cor e Forma:SolidPeso molecular:481.51Obidoxime dichloride
CAS:Obidoxime dichloride is an antidote for organophosphate poisoning that enhances the positive inotropic effect of phosphamidon on isolated working rat hearts.Fórmula:C14H16Cl2N4O3Pureza:98%Cor e Forma:SolidPeso molecular:359.21SB-269970
CAS:SB-269970 is a antagonist of 5-HT7 receptor(pKi of 8.3).Fórmula:C18H28N2O3SPureza:98%Cor e Forma:SolidPeso molecular:352.49Bitopertin (R enantiomer)
CAS:Bitopertin R enantiomer (RG1678 R enantiomer) is the R-enantiomer of Bitopertin.Fórmula:C21H20F7N3O4SPureza:98%Cor e Forma:SolidPeso molecular:543.46MAO-B-IN-23
CAS:MAO-B-IN-23, also known as Compound 11f, is a reversible and competitive monoamine oxidase B (MAO-B) inhibitor with an IC50 value of 1.44 μM and a Ki of 0.51 μMFórmula:C19H18BrNOPureza:98%Cor e Forma:SolidPeso molecular:356.26GlyT1 Inhibitor 1
CAS:GlyT1 Inhibitor 1 is a selective and potent GlyT1 inhibitor, inhibiting rGlyT1, used in research on neurological disorders.Fórmula:C22H21N5O2Cor e Forma:SolidPeso molecular:387.43ETAP
CAS:ETAP, a dual inhibitor of both monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B), exhibits antidepressant-like effects and is utilized in the researchFórmula:C18H17N3OPureza:98%Cor e Forma:SolidPeso molecular:291.35VU0155041 sodium
CAS:VU0155041 sodium is a positive allosteric modulator of mGluR4 that promotes extinction in male rats.Fórmula:C14H14Cl2NNaO3Pureza:98%Cor e Forma:SolidPeso molecular:338.16Usmarapride free base
CAS:Usmarapride free base (SUVN-D4010 free base) is a partial agonist of 5-HT4 receptors, used in Alzheimer's disease research.Fórmula:C21H29N5O2Pureza:99.91% - 99.91%Cor e Forma:SolidPeso molecular:383.49MHP 133
CAS:MHP 133 is a drug with multiple CNS targets(AChE with Ki of 69 μM).Fórmula:C17H20ClN5O3Pureza:98%Cor e Forma:SolidPeso molecular:377.83Lintopride
CAS:Lintopride is an antagonist of 5HT4. It has moderate 5HT3 antagonist properties.Fórmula:C14H19ClN4O2Pureza:98%Cor e Forma:SolidPeso molecular:310.78PCS1055 dihydrochloride
CAS:PCS1055 is a selective M4 antagonist (IC50: 18.1 nM, Ki: 6.5 nM) and potent AChE inhibitor with >100-fold M1/M3/M5 selectivity.Fórmula:C27H34Cl2N4Pureza:98%Cor e Forma:SolidPeso molecular:485.49OPC-14523 hydrochloride
CAS:OPC-14523 hydrochloride, an oral sigma/5-HT1A agonist, shows potent antidepressant activity with strong receptor affinity.Fórmula:C23H29Cl2N3O2Pureza:99.60%Cor e Forma:SolidPeso molecular:450.4SLV-310
CAS:SLV-310 is a D2 receptor antagonist and 5-HT reuptake receptor inhibitor for the study of neurological disorders such as bipolar disorder and schizophrenia.Fórmula:C25H24FN3O2Pureza:99.39%Cor e Forma:SolidPeso molecular:417.48PF-03463275
CAS:PF-03463275 is an orally active and selective reversible inhibitor of competitive glycine transporter protein-1 (GlyT1) with a Ki of 11.6 nM.PF-03463275 has CNS
Fórmula:C19H22ClFN4OPureza:99.86%Cor e Forma:SolidPeso molecular:376.86CDD0102
CAS:CDD0102 is a potent agonist of M1 Muscarinic receptor.Fórmula:C8H12N4OPureza:98%Cor e Forma:SolidPeso molecular:180.21PNU-96391
CAS:PNU-96391 (OSU-6162) is an antagonist of dopamine D2 and a partial agonist of 5-HT2A. PNU-96391 can be used in research on the treatment of chronic diseases.Fórmula:C15H23NO2SPureza:99.53%Cor e Forma:SolidPeso molecular:281.41Ref: TM-T28435
1mg73,00€1mL*10mM (DMSO)138,00€5mg146,00€10mg210,00€25mg319,00€50mg447,00€100mg600,00€200mg800,00€BTA-1
CAS:BTA-1 is an uncharged derivative of thioflavin-T that has high affinity for Aβ fibrils and shows very good brain entry and clearance [1].Fórmula:C14H12N2SCor e Forma:SolidPeso molecular:240.32SB 714786
CAS:SB 714786 is a selective antagonist of 5-HT1D.Fórmula:C26H28N4OPureza:98%Cor e Forma:SolidPeso molecular:412.53R-PSOP
CAS:R-PSOP, a selective NMUR2 antagonist, binds human/rat receptors with 52/32 nM affinity, useful for CNS-related disorders.Fórmula:C20H22N4O2Cor e Forma:SolidPeso molecular:350.41PQCA
CAS:PQCA is a selective M1 receptor modulator with EC50s of 49 nM (monkey) and 135 nM (human), potential for Alzheimer's treatment.Fórmula:C22H20N4O3Pureza:99.88%Cor e Forma:SolidPeso molecular:388.42Isamoltane
CAS:Isamoltane is a serotonin 5-HT1 Receptor AntagonistFórmula:C16H23ClN2O2Cor e Forma:SolidPeso molecular:310.82Ro 15-1310
CAS:Ro 15-3505, a benzodiazepine receptor partial inverse agonist, has shown the ability to improve impaired recent memory of aged mice.Fórmula:C15H14ClN3O3Cor e Forma:SolidPeso molecular:319.74Alaproclate
CAS:Alaproclate is a non-competitive NMDA receptor antagonist and a new selective 5-HT uptake inhibitor for the study of depression and dementia.Fórmula:C13H18ClNO2Pureza:98.29% - 98.64%Cor e Forma:SolidPeso molecular:255.74AZD 3043
CAS:AZD 3043 (THRX 918661) is a modulator of the gamma-aminobutyric acid type A receptor, a novel sedative-hypnotic, and a potential short-acting anesthetic.Fórmula:C19H29NO5Pureza:98.19% - 99.55%Cor e Forma:SolidPeso molecular:351.44PNU-142633
CAS:PNU-142633: anti-migraine, selective 5-HT1D agonist, Ki=6 nM; >18,000 nM for 5-HT1B.Fórmula:C24H30N4O3Pureza:98%Cor e Forma:SolidPeso molecular:422.52(R)-Duloxetine Hydrochloride
CAS:(R)-Duloxetine Hydrochloride, naphthalenyloxy amine, binds human serum albumin, less effective than (S)-enantiomer as SNRI.Fórmula:C18H20ClNOSCor e Forma:SolidPeso molecular:333.87Glutaminyl Cyclase Inhibitor 5
Glutaminyl Cyclase Inhibitor 5 is a potent, selective inhibitor of human glutaminyl cyclase (hQC), demonstrating an inhibition concentration half-max (IC 50) ofFórmula:C22H30N6OCor e Forma:SolidPeso molecular:394.51Elzasonan
CAS:Elzasonan is a selective 5-hydroxytryptamine 1B receptor antagonist used to treat patients with major depressive disorder and obsessive compulsive disorder.Fórmula:C22H23Cl2N3OSCor e Forma:SolidPeso molecular:448.41YM-58790
CAS:YM-58790 is a potent mAChR blocker with Ki values of 28 nM (M1), 260 nM (M2), 15 nM (M3), and reduces bladder contractions in rats.Fórmula:C27H31N3O2Pureza:99.87%Cor e Forma:SoildPeso molecular:429.55TC-1698 dihydrochloride
CAS:TC-1698 dihydrochloride: selective α7 nicotinic agonist, with some β-receptor activity; neuroprotectant.Fórmula:C13H20Cl2N2Cor e Forma:SolidPeso molecular:275.22AZD-9164 bromide
CAS:AMG-221, a selective 11β-HSD1 inhibitor, suppresses enzyme activity, lowers glucose/insulin, and reduces weight in obese mice.Fórmula:C29H38BrFN2O2Cor e Forma:SolidPeso molecular:545.53Metanicotine
CAS:Metanicotine is a selective nicotinic agonist with antinociceptive properties.Fórmula:C10H14N2Cor e Forma:SolidPeso molecular:162.23Fonazine mesylate
CAS:Fonazine mesylate is a phenothiazine drug used for the treatment of migraine. It is a serotonin antagonist and histamine antagonist.Fórmula:C20H29N3O5S3Cor e Forma:SolidPeso molecular:487.65VER-3323
CAS:VER-3323 is a selective agonist for the 5-HT2B and 5-HT2C serotonin receptor with potent anorectic effects in animal studies.Fórmula:C11H15BrN2Pureza:98%Cor e Forma:SolidPeso molecular:255.15Echothiophate chloride
CAS:Echothiophate: long-lasting cholinesterase inhibitor for chronic glaucoma treatment; binds irreversibly, inactivating the enzyme.Fórmula:C9H23ClNO3PSCor e Forma:SolidPeso molecular:291.7708Pridefine
CAS:Pridefine: antidepressant, balances serotonin, dopamine, norepinephrine reuptake, weakly releases them.Fórmula:C19H21NPureza:99.15% - 99.66%Cor e Forma:SolidPeso molecular:263.38Methacholine iodide
CAS:Methacholine iodide is a muscarinic acetylcholine receptor agonist.Fórmula:C8H18INO2Cor e Forma:SolidPeso molecular:287.14VU0486321
CAS:VU0486321: potent mGlu1 PAM, rat PK CLp 13.3 mL/min/kg, t1/2 54 min, human fu 0.05, rat fu 0.03, great CNS penetration Kp 1.02.Fórmula:C20H12ClFN2O4Cor e Forma:SolidPeso molecular:398.77MD 780236
CAS:MD 780236 is a monoamine oxidase-B inhibitor.Fórmula:C18H19ClN2O3Cor e Forma:SolidPeso molecular:346.81Neostigmine hydroxide
CAS:Neostigmine hydroxide, a cholinesterase inhibitor, treats myasthenia gravis and reverses muscle relaxants; doesn't cross the blood-brain barrier.Fórmula:C12H20N2O3Cor e Forma:SolidPeso molecular:240.3Ciclotizolam
CAS:Ciclotizolam, a thienotriazolodiazepine derivative and partial GABAA receptor agonist, has low efficacy but similar affinity as brotizolam.Fórmula:C20H18BrClN4SCor e Forma:SolidPeso molecular:461.81Dexetimide HCl
CAS:Dexetimide HCl is a muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide.Fórmula:C23H27ClN2O2Cor e Forma:SolidPeso molecular:398.93SC 53116 Hydrochloride
CAS:SC 53116 Hydrochloride is selective agonist of the newly identified serotonin 5-HT4 receptor subtype.Fórmula:C16H23Cl2N3O2Cor e Forma:SolidPeso molecular:360.284-Chloro Trazodone hydrochloride
CAS:4-Chloro Trazodone HCl is a Trazodone isomer, an antidepressant for anxiety disorders.Fórmula:C19H23Cl2N5OCor e Forma:SolidPeso molecular:408.32Eptapirone fumarate
CAS:Eptapirone (F11440) is a strong 5HT1A agonist with high anxiolytic and antidepressant effects, more potent than buspirone and flesinoxan.Fórmula:C20H27N7O6Cor e Forma:SolidPeso molecular:461.479SZV558
CAS:SZV558: Strong MAO-B inhibitor, non-mutagenic, hERG-safe, high-dose tolerant, neuroprotective in PD model.Fórmula:C13H16ClNPureza:98%Cor e Forma:SolidPeso molecular:221.73mAChr-in-1
CAS:mAChR-IN-1 is muscarinic cholinergic receptor(mAChR) antagonist (IC50=17 nM).Fórmula:C23H25IN2O2Pureza:98%Cor e Forma:SolidPeso molecular:488.36CHF5407
CAS:CHF5407（SVT-47060） is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect onFórmula:C27H25BrF4N2O3SPureza:99.54% - >99.99%Cor e Forma:SolidPeso molecular:613.46YM-46303
CAS:YM-46303 is a selective and potent muscarinic receptor antagonist that exhibits high affinity for the M3 receptor.YM-46303 can be used to study bradycardia inFórmula:C20H23ClN2O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:358.86
