Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(647 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.025 produtos)
- BACE(37 produtos)
- Beta Amilóide(230 produtos)
- CaMK(73 produtos)
- COX(602 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(373 produtos)
- Gama-secretase(62 produtos)
- GluR(265 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(43 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(41 produtos)
- Receptor opioide(327 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5639 produtos de "Neurociência"
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VU0409106
CAS:VU0409106 is a potent, mGlu5-selective inhibitor.Fórmula:C15H11FN4O2SPureza:98%Cor e Forma:SolidPeso molecular:330.34Deramciclane fumarate
CAS:Deramciclane fumarate is a 5-HT(2A/C) antagonist with putative anxiolytic activity.Fórmula:C24H35NO5Cor e Forma:SolidPeso molecular:417.54J-104129 fumarate
CAS:J-104129 fumarate is a potent M3 muscarinic receptor antagonist.Fórmula:C28H40N2O6Cor e Forma:SolidPeso molecular:500.63Pridefine
CAS:Pridefine: antidepressant, balances serotonin, dopamine, norepinephrine reuptake, weakly releases them.Fórmula:C19H21NPureza:99.15% - 99.66%Cor e Forma:SolidPeso molecular:263.38mGluR2 modulator 4
CAS:Compound 47 is a potent mGluR2 enhancer with an EC50 of 0.8 μM, potentially useful for antipsychotic research.Fórmula:C18H18BrN3Cor e Forma:SolidPeso molecular:356.26DMeOB
CAS:DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and is used in the study of neurological disorders.Fórmula:C16H16N2O2Pureza:98.34%Cor e Forma:SolidPeso molecular:268.31VU0400195
CAS:VU0400195 is a oral effective, positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu(4)).Fórmula:C21H16ClN3O3Pureza:98%Cor e Forma:SolidPeso molecular:393.82E-3620
CAS:E-3620 is a potent antagonist of the 5-HT3 receptor and can be used to study dyskinesia and gastrointestinal dysfunction.Fórmula:C20H27Cl2N3O2Pureza:98.88% - 98.88%Cor e Forma:SolidPeso molecular:412.35VU6010572
CAS:VU6010572: potent, selective mGlu3 modulator, IC50 245 nM, high CNS penetration.Fórmula:C20H18FNO3Cor e Forma:SolidPeso molecular:339.36MS 245 oxalate
CAS:MS 245 oxalate is a 5-HT6 antagonist.Fórmula:C21H24N2O7SPureza:98%Cor e Forma:SolidPeso molecular:448.49AChE-IN-21
CAS:AChE-IN-21 (I-8), potent, selective AChE inhibitor, IC50: 2.66 nM, good BBB permeability.Fórmula:C24H29NO4Cor e Forma:SolidPeso molecular:395.49AChE-IN-12
CAS:AChE-IN-12 inhibited rat/eel AChE, crossed BBB, prevented Aβ1-42 aggregation, and has potential for Alzheimer's research.Fórmula:C33H41NO7Cor e Forma:SolidPeso molecular:563.68ST1936
CAS:ST1936 (ST 1936 oxalate) is a 5-HT6 receptor agonist that stimulates cAMP, Ca2+, ERK1/2, and Fyn kinases by fully activating cloned human 5-HT6 receptors.Fórmula:C13H17ClN2Pureza:98%Cor e Forma:SolidPeso molecular:236.74Ref: TM-T23396
1mg44,00€5mg111,00€1mL*10mM (DMSO)123,00€10mg178,00€25mg316,00€50mg470,00€100mg682,00€200mg954,00€Melatonin receptor agonist 1
CAS:Melatonin receptor agonist 1 (compound 20c) is a potent agonist of melatonin receptor (MT) with Ki values of 108 nM for MT2 and 1140 nM for MT 1 [1].Fórmula:C15H19N3O2Cor e Forma:SolidPeso molecular:273.338-M-PDOT
CAS:8-M-PDOT (AH-002) is an MT2 receptor agonist that inhibits MT1.8-M-PDOT has anxiolytic activity and may be used in the study of neuropathic pain.Fórmula:C14H19NO2Pureza:99.54% - 99.54%Cor e Forma:SolidPeso molecular:233.31Glemanserin
CAS:Glemanserin (MDL11939) is a specific 5-HT2A antagonist with Ki values of 0.54 nM, 2.5 nM and 2.89 nM for rabbit, human and rat 5-HT2A.Fórmula:C20H25NOPureza:99.93%Cor e Forma:SolidPeso molecular:295.42Ref: TM-T22964
1mg38,00€5mg84,00€1mL*10mM (DMSO)84,00€10mg119,00€25mg259,00€50mg409,00€100mg605,00€500mg1.288,00€Dual AChE-MAO B-IN-2
CAS:Potent Dual AChE-MAO B-IN-2 inhibits AChE (0.12 μM) & MAO B (0.01 μM); promising for Alzheimer's research.Fórmula:C26H25NO4Cor e Forma:SolidPeso molecular:415.48Tracazolate hydrochloride
CAS:Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity.Fórmula:C16H25ClN4O2Pureza:99.52%Cor e Forma:SolidPeso molecular:340.85NW-1772
CAS:NW-1772 is a highly potent and orally active inhibitor of monoamine oxidase B.Fórmula:C19H20ClNO6SPureza:98%Cor e Forma:SolidPeso molecular:425.882-Iodomelatonin
CAS:2-Iodomelatonin, Ki 28 pM, is an MT1 agonist, >5x selective over MT2, used to map melatonin sites in brain/tissues.Fórmula:C13H15IN2O2Pureza:99.7%Cor e Forma:SolidPeso molecular:358.17Ref: TM-T10073
500mgA consultar1mL*10mM (DMSO)34,00€10mg43,00€25mg79,00€50mg118,00€100mg178,00€200mg268,00€p-MPPF dihydrochloride
CAS:p-MPPF dihydrochloride is a 5-HT antagonist that can be used to study neurological diseases.Fórmula:C25H29Cl2FN4O2Pureza:99.55%Cor e Forma:SolidPeso molecular:507.43Nerispirdine HCl
CAS:Nerispirdine enhances acetylcholine, blocks Na+ channels (IC50 11.9µM) and K(v) 1.1/1.2 channels (IC50 3.6/3.7µM).Fórmula:C17H19ClFN3Pureza:98%Cor e Forma:SolidPeso molecular:319.8ASP2535
CAS:ASP2535 is a potent, selective, orally bioavailable, brain permeable and centrally-active glycine transporter-1 (GlyT1) inhibitor.ASP2535 can improve cognitiveFórmula:C22H18N6OPureza:98%Cor e Forma:SolidPeso molecular:382.42MAO-IN-M30 dihydrochloride
CAS:MAO-IN-M30 dihydrochloride: potent, brain-specific MAO-A/B inhibitor, iron chelator with antioxidant effects, counters Parkinson's in mice.Fórmula:C14H16Cl2N2OPureza:99.83%Cor e Forma:SolidPeso molecular:299.2Ref: TM-T38034
500mgA consultar1mg34,00€2mg43,00€5mg65,00€10mg90,00€25mg161,00€50mg230,00€100mg319,00€VU0155041 sodium
CAS:VU0155041 sodium is a positive allosteric modulator of mGluR4 that promotes extinction in male rats.Fórmula:C14H14Cl2NNaO3Pureza:98%Cor e Forma:SolidPeso molecular:338.16Ampreloxetine
CAS:Ampreloxetine (TD-9855) is a norepinephrine reuptake inhibitor used to study neurological diseases.Fórmula:C18H18F3NOPureza:98%Cor e Forma:SolidPeso molecular:321.34ML289
CAS:ML289 is a potent CNS-penetrant mGlu3 modulator with IC50 of 0.66 μM, >15-fold selectivity over mGlu2, and inactive against mGlu5.Fórmula:C22H23NO3Pureza:99.54%Cor e Forma:SolidPeso molecular:349.42Ref: TM-T23000
5mg48,00€1mL*10mM (DMSO)49,00€10mg75,00€25mg138,00€50mg212,00€100mg320,00€200mg445,00€LY487379 hydrochloride
CAS:Positive allosteric modulator of mGlu2 receptorsFórmula:C21H20ClF3N2O4SPureza:98%Cor e Forma:SolidPeso molecular:488.91AC260584
CAS:AC260584 is an M1 muscarinic receptor allosteric agonist (pEC50: 7.6).Fórmula:C20H29FN2O2Cor e Forma:SolidPeso molecular:348.45F13714 fumarate
CAS:F13714 fumarate is a 5-HT1A receptor-biased agonist.Fórmula:C25H29ClF2N4O5Pureza:98.86%Cor e Forma:SolidPeso molecular:538.97NB001
CAS:NB001 (HTS 09836) is an inhibitor of adenyl cyclase 1 exhibiting effects on neural and non-neural pain.Fórmula:C12H20N6OPureza:99.69%Cor e Forma:Off-White To Pale Pink SolidPeso molecular:264.33Ref: TM-T16275
1mg74,00€1mL*10mM (DMSO)173,00€5mg200,00€10mg295,00€25mg497,00€50mg710,00€100mg964,00€500mg1.935,00€Valiglurax
CAS:Valiglurax (VU2957), potent mGlu4 PAM, crosses blood-brain barrier, orally available; promising for Parkinson's treatment.Fórmula:C16H10F3N5Pureza:98.29%Cor e Forma:SolidPeso molecular:329.28Perphenazine dihydrochloride
CAS:Perphenazine dihydrochloride: Oral dopamine, histamine-1 antagonist; targets D2, D3, 5-HT2A, Alpha-1A; may treat psychiatric disorders, cancer.Fórmula:C21H28Cl3N3OSPureza:99.67%Cor e Forma:SolidPeso molecular:476.89Otenzepad
CAS:Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung.Fórmula:C24H31N5O2Pureza:99.79%Cor e Forma:SolidPeso molecular:421.54Ref: TM-T16411
1mg44,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg114,00€25mg222,00€50mg356,00€100mg572,00€200mg803,00€MAO-B-IN-9
CAS:MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence.Fórmula:C18H24N2O2Pureza:99.93%Cor e Forma:SolidPeso molecular:300.4Ref: TM-T60671
2mg39,00€5mg58,00€1mL*10mM (DMSO)66,00€10mg93,00€25mg167,00€50mg260,00€100mg378,00€200mg552,00€Goxalapladib
CAS:Goxalapladib（GSK 677116） is a small molecule compound that can be used to treat cardiovascular risks associated with atherosclerosis.Fórmula:C40H39F5N4O3Pureza:99.64% - 99.93%Cor e Forma:SolidPeso molecular:718.75CP-810123
CAS:CP-810123 is an α7 nAChR agonist used to treat cognitive deficits associated with psychiatric or neurological disorders such as schizophrenia.Fórmula:C14H18N4OPureza:98.63% - 99.60%Cor e Forma:SolidPeso molecular:258.32NNC 05-2090 hydrochloride
CAS:NNC 05-2090 HCl: BGT-1 inhibitor, IC50 = 10.6 μM, potential for epilepsy, neurological research.Fórmula:C27H31ClN2O2Pureza:99.11%Cor e Forma:SolidPeso molecular:451SB-215505
CAS:SB215505: potent 5-HT2B/2C blocker, enhances rat wakefulness/motor activity. (pKi: 5-HT2B - 8.3, 5-HT2C - 7.66, 5-HT2A - 6.77).Fórmula:C19H16ClN3OPureza:98.33%Cor e Forma:SolidPeso molecular:337.8Viloxazine
CAS:Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activityFórmula:C13H19NO3Pureza:99.65%Cor e Forma:SolidPeso molecular:237.29PNU-282987 free base
CAS:PNU-282987 is an α7 nAChR agonist (EC50=154 nM) and a 5-HT3 antagonist (IC50=4541 nM) for nervous system research.
Fórmula:C14H17ClN2OPureza:99.64%Cor e Forma:SolidPeso molecular:264.75PHA 543613
CAS:PHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia.Fórmula:C15H17N3O2Pureza:99.43% - 99.96%Cor e Forma:SolidPeso molecular:271.31Ref: TM-T23145
1mg52,00€1mL*10mM (DMSO)100,00€5mg102,00€10mg166,00€25mg358,00€50mg610,00€100mg895,00€500mg1.945,00€ADR-851 free base
CAS:ADR-851 free base is an antagonist of the HT3 receptor.Fórmula:C14H18ClN3O2Pureza:97.88% - 98.39%Cor e Forma:SolidPeso molecular:295.77Sarizotan HCl
CAS:Sarizotan HCl (EMD 128130 HCl) is a 5-HT1A receptor and dopamine receptor agonist and an hERG channel inhibitor used in Parkinson;s disease research.Fórmula:C22H22ClFN2OPureza:96%Cor e Forma:SolidPeso molecular:384.87amyloid P-IN-1
CAS:amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer's disease, amyloidosis, osteoarthritis, andFórmula:C30H44N2O14Pureza:99.76%Cor e Forma:SolidPeso molecular:656.68DSP-0565
CAS:DSP-0565 is a broad-spectrum anti-epileptic with a high safety margin and effectiveness in several convulsant models.Fórmula:C14H12FNOPureza:99.51% - 99.56%Cor e Forma:SolidPeso molecular:229.25Ref: TM-T11106
1mg109,00€2mg163,00€1mL*10mM (DMSO)208,00€5mg241,00€10mg354,00€25mg532,00€50mg745,00€100mg1.018,00€500mg2.035,00€RWJ-51204
CAS:RWJ-51204: potent adenosine A2A blocker, GABA(A) partial agonist (IC50: 0.2-2 nM), neuroprotective, may treat Parkinson's.
Fórmula:C21H19F2N3O3Pureza:99.57% - 99.95%Cor e Forma:SolidPeso molecular:399.39Ref: TM-T16811
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€MNI 137
CAS:MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat.Fórmula:C15H9BrN4OPureza:97.49%Cor e Forma:SolidPeso molecular:341.16LY 272015 hydrochloride
CAS:LY 272015 hydrochloride is a 5-HT2B receptor antagonist.Fórmula:C21H25ClN2O2Pureza:99.47%Cor e Forma:SolidPeso molecular:372.89H-9 dihydrochloride
CAS:H-9 dihydrochloride: Strong PKA inhibitor, curbs 5-HT response and EGF signaling, affects pharyngeal function.Fórmula:C11H15Cl2N3O2SPureza:97.3%Cor e Forma:SolidPeso molecular:324.23
